Gene2Function: An integrated online resource for gene function discovery

G3: Genes, Genomes, Genetics

Volumn 7, Issue 8, 2017, Pages 2855-2858

  Hu, Yanhui ^a   Comjean, Aram ^a   Mohr, Stephanie E ^a   Perrimon, Norbert ^a,b,f   Agapite, Julie ^b   Broll, Kris ^b   Crosby, Madeline ^b   Dos Santos, Gilberto ^b   Emmert, David ^b   Falls, Kathleen ^b   Gelbart, Susan Russo ^b   Gramates, L Sian ^b   Matthews, Beverley ^b   Sutherland, Carol ^b   Tabone, Chris ^b   Zhou, Pinglei ^b   Zytkovicz, Mark ^b   Antonazzo, Giulia ^c   Attrill, Helen ^c   Brown, Nicholas ^c   Fexova, Silvie ^c   Garapati, Phani ^c   Jones, Tamsin ^c   Larkin, Aoife ^c   Marigold, Steven ^c   Millburn, Gillian ^c   Rey, Alix ^c   Trovisco, Vitor ^c   Urbano, Jose Maria ^c   Czoch, Brian ^d   Goodman, Josh ^d   Grumbling, Gary ^d   Kaufman, Thomas ^d   Strelets, Victor ^d   Thurmond, James ^d   Baker, Phillip ^e   Cripps, Richard ^e   Werner Washburne, Margaret ^e   more..

^a HARVARD MEDICAL SCHOOL   (United States)

^b HARVARD UNIVERSITY   (United States)

^c UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^d INDIANA UNIVERSITY   (United States)

^e UNIVERSITY OF NEW MEXICO   (United States)

^f HOWARD HUGHES MEDICAL INSTITUTE   (United States)

Author keywords

Data mining; functional genomics; Human genetic disease; Model organism databases; Orthologs

Indexed keywords

ARTICLE; DATA MINING; FUNCTIONAL GENOMICS; GENE FUNCTION; GENE SEQUENCE; GENETIC ANALYSIS; GENETIC DATABASE; ONLINE SYSTEM; DISEASES; GENE; GENETICS; INTERNET;

DATABASES, GENETIC; DISEASE; GENES; INTERNET;

EID: 85027251911     PISSN: None     EISSN: 21601836     Source Type: Journal    
DOI: 10.1534/g3.117.043885     Document Type: Article

References (23)

1. Blake, J. A., J. T. Eppig, J. A. Kadin, J. E. Richardson, C. L. Smith et al., 2017 Mouse genome database (MGD)-2017: community knowledge resource for the laboratory mouse. Nucleic Acids Res. 45: D723-D729
2. Cherry, J. M., E. L. Hong, C. Amundsen, R. Balakrishnan, G. Binkley et al., 2012 Saccharomyces genome database: the genomics resource of budding yeast. Nucleic Acids Res. 40: D700-D705
3. Eeles, R. A., A. A. Olama, S. Benlloch, E. J. Saunders, D. A. Leongamornlert et al., 2013 Identification of 23 new prostate cancer susceptibility loci using the iCOGS custom genotyping array. Nat Genet. 45: 385-391, 391e381-391e382
4. Gramates, L. S., S. J.Marygold, G. D. Santos, J.M. Urbano, G. Antonazzo et al., 2017 FlyBase at 25: looking to the future. Nucleic Acids Res. 45: D663-D671
5. Howe, D. G., Y. M. Bradford, A. Eagle, D. Fashena, K. Frazer et al., 2017 The Zebrafish model organism database: new support for human disease models, mutation details, gene expression phenotypes and searching. Nucleic Acids Res. 45: D758-D768
6. Howe, K. L., B. J. Bolt, S. Cain, J. Chan, W. J. Chen et al., 2016 WormBase 2016: expanding to enable helminth genomic research. Nucleic Acids Res. 44: D774-D780
7. Hu, Y., A. Rolfs, B. Bhullar, T. V. Murthy, C. Zhu et al., 2007 Approaching a complete repository of sequence-verified protein-encoding clones for Saccharomyces cerevisiae. Genome Res. 17: 536-543
8. Hu, Y., I. Flockhart, A. Vinayagam, C. Bergwitz, B. Berger et al., 2011 An integrative approach to ortholog prediction for disease-focused and other functional studies. BMC Bioinformatics 12: 357
9. Hu, Y., A. Comjean, N. Perrimon, and S. E. Mohr, 2017 The Drosophila Gene Expression Tool (DGET) for expression analyses. BMC Bioinformatics 18: 98
10. Karpinka, J. B., J. D. Fortriede, K. A. Burns, C. James-Zorn, V. G. Ponferrada et al., 2015 Xenbase, the Xenopus model organism database; new virtualized system, data types and genomes. Nucleic Acids Res. 43: D756-D763
11. Lamesch, P., S. Milstein, T. Hao, J. Rosenberg, N. Li et al., 2004 C. elegans ORFeome version 3.1: increasing the coverage of ORFeome resources with improved gene predictions. Genome Res. 14: 2064-2069
12. MacArthur, J., E. Bowler, M. Cerezo, L. Gil, P. Hall et al., 2017 The new NHGRI-EBI Catalog of published genome-wide association studies (GWAS Catalog). Nucleic Acids Res. 45: D896-D901
13. McDowall, M. D., M. A. Harris, A. Lock, K. Rutherford, D. M. Staines et al., 2015 PomBase 2015: updates to the fission yeast database. Nucleic Acids Res. 43: D656-D661
14. Mungall, C. J., J. A. McMurry, S. Kohler, J. P. Balhoff, C. Borromeo et al., 2017 The Monarch Initiative: an integrative data and analytic platform connecting phenotypes to genotypes across species. Nucleic Acids Res. 45: D712-D722
15. ORFeome Collaboration, 2016 The ORFeome Collaboration: a genomescale human ORF-clone resource. Nat. Methods 13: 191-192
16. Ripke, S., C. O'Dushlaine, K. Chambert, J. L. Moran, A. K. Kahler et al., 2013 Genome-wide association analysis identifies 13 new risk loci for schizophrenia. Nat. Genet. 45: 1150-1159
17. Rose, P. W., A. Prlic, A. Altunkaya, C. Bi, A. R. Bradley et al., 2017 The RCSB protein data bank: integrative view of protein, gene and 3D structural information. Nucleic Acids Res. 45: D271-D281
18. Schizophrenia Working Group of the Psychiatric Genomics Consortium, 2014 Biological insights from 108 schizophrenia-associated genetic loci. Nature 511: 421-427
19. Shimoyama, M., J. De Pons, G. T. Hayman, S. J. Laulederkind, W. Liu et al., 2015 The rat genome database 2015: genomic, phenotypic and environmental variations and disease. Nucleic Acids Res. 43: D743-D750
20. Smith, R. N., J. Aleksic, D. Butano, A. Carr, S. Contrino et al., 2012 InterMine: a flexible data warehouse system for the integration and analysis of heterogeneous biological data. Bioinformatics 28: 3163-3165
21. Wang, J., R. Al-Ouran, Y. Hu, S. Y. Kim, Y.W. Wan et al., 2017 MARRVEL: integration of human and model organism genetic resources to facilitate functional annotation of the human genome. Am. J. Hum. Genet. 100: 843-853
22. Wangler, M. F., Y. Hu, and J. M. Shulman, 2017 Drosophila and genomewide association studies: a review and resource for the functional dissection of human complex traits. Dis. Model. Mech. 10: 77-88
23. Zuo, D., S. E. Mohr, Y. Hu, E. Taycher, A. Rolfs et al., 2007 PlasmID: a centralized repository for plasmid clone information and distribution. Nucleic Acids Res. 35: D680-D684