-
1
-
-
0024328536
-
Altering the genome by homologous recombination
-
Capecchi MR. Altering the genome by homologous recombination. Science. 1989; 244: 1288-92.
-
(1989)
Science.
, vol.244
, pp. 1288-1292
-
-
Capecchi, M.R.1
-
2
-
-
0030032063
-
Hybrid restriction enzymes: Zinc finger fusions to Fok i cleavage domain
-
Kim YG, Cha J, Chandrasegaran S. Hybrid restriction enzymes: zinc finger fusions to Fok I cleavage domain. Proc Natl Acad Sci USA. 1996; 93: 1156-60.
-
(1996)
Proc Natl Acad Sci USA.
, vol.93
, pp. 1156-1160
-
-
Kim, Y.G.1
Cha, J.2
Chandrasegaran, S.3
-
3
-
-
78951479577
-
Targeting DNA double-strand breaks with TAL effector nucleases
-
Christian M, Cermak T, Doyle EL, Schmidt C, Zhang F, Hummel A, et al. Targeting DNA double-strand breaks with TAL effector nucleases. Genetics. 2010; 186: 757-61.
-
(2010)
Genetics.
, vol.186
, pp. 757-761
-
-
Christian, M.1
Cermak, T.2
Doyle, E.L.3
Schmidt, C.4
Zhang, F.5
Hummel, A.6
-
4
-
-
84873729095
-
Multiplex genome engineering using CRISPR/Cas systems
-
Cong L, Ran FA, Cox D, Lin S, Barretto R. Multiplex genome engineering using CRISPR/Cas systems. Science. 2013; 339: 819-23.
-
(2013)
Science.
, vol.339
, pp. 819-823
-
-
Cong, L.1
Ran, F.A.2
Cox, D.3
Lin, S.4
Barretto, R.5
-
5
-
-
84873734105
-
RNA-guided human genome engineering via Cas9
-
Mali P, Yang L, Esvelt KM, Aach J, Guell M, DiCarlo JE, et al. RNA-guided human genome engineering via Cas9. Science. 2013; 339: 823-6.
-
(2013)
Science.
, vol.339
, pp. 823-826
-
-
Mali, P.1
Yang, L.2
Esvelt, K.M.3
Aach, J.4
Guell, M.5
DiCarlo, J.E.6
-
6
-
-
84865070369
-
A programmable dual-RNA-guided DNA endonuclease in adaptive bacterial immunity
-
Jinek M, Chylinski K, Fonfara I, Hauer M, Doudna JA, Charpentier E. A programmable dual-RNA-guided DNA endonuclease in adaptive bacterial immunity. Science. 2012; 337: 816-21.
-
(2012)
Science.
, vol.337
, pp. 816-821
-
-
Jinek, M.1
Chylinski, K.2
Fonfara, I.3
Hauer, M.4
Doudna, J.A.5
Charpentier, E.6
-
7
-
-
84877103949
-
Generation of gene-modified mice via Cas9/RNA-mediated gene targeting
-
Shen B, Zhang J, Wu H, Wang J, Ma K, Li Z, et al. Generation of gene-modified mice via Cas9/RNA-mediated gene targeting. Cell Res. 2013; 23: 720-3.
-
(2013)
Cell Res.
, vol.23
, pp. 720-723
-
-
Shen, B.1
Zhang, J.2
Wu, H.3
Wang, J.4
Ma, K.5
Li, Z.6
-
8
-
-
84877707375
-
One-step generation of mice carrying mutations in multiple genes by CRISPR/Cas-mediated genome engineering
-
Wang H, Yang H, Shivalila CS, Dawlaty MM, Cheng AW, Zhang F, Jaenisch R. One-step generation of mice carrying mutations in multiple genes by CRISPR/Cas-mediated genome engineering. Cell. 2013; 153: 910-8.
-
(2013)
Cell.
, vol.153
, pp. 910-918
-
-
Wang, H.1
Yang, H.2
Shivalila, C.S.3
Dawlaty, M.M.4
Cheng, A.W.5
Zhang, F.6
Jaenisch, R.7
-
9
-
-
84903185106
-
Rapid generation of mouse models with defined point mutations by the CRISPR/Cas9 system
-
Inui M, Miyado M, Igarashi M, Tamano M, Kubo A, Yamashita S, et al. Rapid generation of mouse models with defined point mutations by the CRISPR/Cas9 system. Sci Rep. 2014; 4: 823.
-
(2014)
Sci Rep.
, vol.4
, pp. 823
-
-
Inui, M.1
Miyado, M.2
Igarashi, M.3
Tamano, M.4
Kubo, A.5
Yamashita, S.6
-
10
-
-
84938945636
-
Cloning-free CRISPR/Cas system facilitates functional cassette knock-in in mice
-
Aida T, Chiyo K, Usami T, Ishikubo H, Imahashi R, Wada Y, et al. Cloning-free CRISPR/Cas system facilitates functional cassette knock-in in mice. Genome Biol. 2015; 16: 507.
-
(2015)
Genome Biol.
, vol.16
, pp. 507
-
-
Aida, T.1
Chiyo, K.2
Usami, T.3
Ishikubo, H.4
Imahashi, R.5
Wada, Y.6
-
11
-
-
84929147435
-
Increasing the efficiency of homology-directed repair for CRISPR-Cas9-induced precise gene editing in mammalian cells
-
Chu VT, Weber T, Wefers B, Wurst W, Sander S. Increasing the efficiency of homology-directed repair for CRISPR-Cas9-induced precise gene editing in mammalian cells. Nature. 2015; 33: 543-8.
-
(2015)
Nature.
, vol.33
, pp. 543-548
-
-
Chu, V.T.1
Weber, T.2
Wefers, B.3
Wurst, W.4
Sander, S.5
-
12
-
-
0037130170
-
Adenovirus oncoproteins inactivate the Mre11-Rad50-NBS1 DNA repair complex
-
Stracker TH, Carson CT, Weitzman MD. Adenovirus oncoproteins inactivate the Mre11-Rad50-NBS1 DNA repair complex. Nature. 2002; 418: 348-52.
-
(2002)
Nature.
, vol.418
, pp. 348-352
-
-
Stracker, T.H.1
Carson, C.T.2
Weitzman, M.D.3
-
13
-
-
68249146431
-
Role of mammalian Mre11 in classical and alternative nonhomologous end joining
-
Xie A, Kwok A, Scully R. Role of mammalian Mre11 in classical and alternative nonhomologous end joining. Nat Struct Mol Biol. 2009; 16: 814-8.
-
(2009)
Nat Struct Mol Biol.
, vol.16
, pp. 814-818
-
-
Xie, A.1
Kwok, A.2
Scully, R.3
-
14
-
-
84929166074
-
Increasing the efficiency of precise genome editing with CRISPR-Cas9 by inhibition of nonhomologous end joining
-
Maruyama T, Dougan SK, Truttmann MC, Bilate AM, Ingram JR, Ploegh HL. Increasing the efficiency of precise genome editing with CRISPR-Cas9 by inhibition of nonhomologous end joining. Nat Biotechnol. 2015; 33: 538-42.
-
(2015)
Nat Biotechnol.
, vol.33
, pp. 538-542
-
-
Maruyama, T.1
Dougan, S.K.2
Truttmann, M.C.3
Bilate, A.M.4
Ingram, J.R.5
Ploegh, H.L.6
-
15
-
-
84871550828
-
An inhibitor of nonhomologous end-joining abrogates double-strand break repair and impedes cancer progression
-
Srivastava M, Nambiar M, Sharma S, Karki SS, Goldsmith G, Hegde M, et al. An inhibitor of nonhomologous end-joining abrogates double-strand break repair and impedes cancer progression. Cell. 2012; 151: 1474-87.
-
(2012)
Cell.
, vol.151
, pp. 1474-1487
-
-
Srivastava, M.1
Nambiar, M.2
Sharma, S.3
Karki, S.S.4
Goldsmith, G.5
Hegde, M.6
-
16
-
-
84961334208
-
RS-1 enhances CRISPR/Cas9-and TALEN-mediated knock-in efficiency
-
Song J, Yang D, Xu J, Zhu T, Chen YE, Zhang J. RS-1 enhances CRISPR/Cas9-and TALEN-mediated knock-in efficiency. Nat Commun. 2016; 7: 10548.
-
(2016)
Nat Commun.
, vol.7
, pp. 10548
-
-
Song, J.1
Yang, D.2
Xu, J.3
Zhu, T.4
Chen, Y.E.5
Zhang, J.6
-
17
-
-
57349128865
-
A chemical compound that stimulates the human homologous recombination protein RAD51
-
Jayathilaka K, Sheridan SD, Bold TD, Bochenska K, Logan HL, Weichselbaum RR, et al. A chemical compound that stimulates the human homologous recombination protein RAD51. Proc Natl Acad Sci USA. 2008; 105: 15848-53.
-
(2008)
Proc Natl Acad Sci USA.
, vol.105
, pp. 15848-15853
-
-
Jayathilaka, K.1
Sheridan, S.D.2
Bold, T.D.3
Bochenska, K.4
Logan, H.L.5
Weichselbaum, R.R.6
-
18
-
-
84940191254
-
The genetics of human infertility by functional interrogation of SNPs in mice
-
Singh P, Schimenti JC. The genetics of human infertility by functional interrogation of SNPs in mice. Proc Natl Acad Sci USA. 2015; 112: 10431-6.
-
(2015)
Proc Natl Acad Sci USA.
, vol.112
, pp. 10431-10436
-
-
Singh, P.1
Schimenti, J.C.2
-
19
-
-
84982705733
-
Loss of function mutation in LOX causes thoracic aortic aneurysm and dissection in humans
-
Lee VS, Halabi CM, Hoffman EP, Carmichael N, Leshchiner I, Lian CG, et al. Loss of function mutation in LOX causes thoracic aortic aneurysm and dissection in humans. Proc Natl Acad Sci USA. 2016; 113: 8759-64.
-
(2016)
Proc Natl Acad Sci USA.
, vol.113
, pp. 8759-8764
-
-
Lee, V.S.1
Halabi, C.M.2
Hoffman, E.P.3
Carmichael, N.4
Leshchiner, I.5
Lian, C.G.6
-
20
-
-
84994589522
-
The p. R92W variant of NR5A1/Nr5a1 induces testicular development of 46, XX gonads in humans, but not in mice: Phenotypic comparison of human patients and mutationinduced mice
-
Miyado M, Inui M, Igarashi M, Katoh-Fukui Y, Takasawa K, Hakoda A, et al. The p. R92W variant of NR5A1/Nr5a1 induces testicular development of 46, XX gonads in humans, but not in mice: phenotypic comparison of human patients and mutationinduced mice. Biol Sex Differ. 2016; 7: 56.
-
(2016)
Biol Sex Differ.
, vol.7
, pp. 56
-
-
Miyado, M.1
Inui, M.2
Igarashi, M.3
Katoh-Fukui, Y.4
Takasawa, K.5
Hakoda, A.6
-
21
-
-
85003706947
-
Identical NR5A1 missense mutations in two unrelated 46, XX individuals with testicular tissues
-
Igarashi M, Takasawa K, Hakoda A, Kanno J, Takada S, Miyado M, et al. Identical NR5A1 missense mutations in two unrelated 46, XX individuals with testicular tissues. Hum Mutat. 2016; 38: 39-42.
-
(2016)
Hum Mutat.
, vol.38
, pp. 39-42
-
-
Igarashi, M.1
Takasawa, K.2
Hakoda, A.3
Kanno, J.4
Takada, S.5
Miyado, M.6
-
23
-
-
0024353559
-
The molecular basis of muscular dystrophy in the mdx mouse: A point mutation
-
Sicinski P, Geng Y, Ryder-Cook A, Barnard E, Darlison M, Barnard P. The molecular basis of muscular dystrophy in the mdx mouse: a point mutation. Science. 1989; 244: 1578-80.
-
(1989)
Science.
, vol.244
, pp. 1578-1580
-
-
Sicinski, P.1
Geng, Y.2
Ryder-Cook, A.3
Barnard, E.4
Darlison, M.5
Barnard, P.6
-
24
-
-
84907200149
-
Prevention of muscular dystrophy in mice by CRISPR/Cas9-mediated editing of germline DNA
-
Long C, McAnally JR, Shelton JM, Mireault AA, Bassel-Duby R, Olson EN. Prevention of muscular dystrophy in mice by CRISPR/Cas9-mediated editing of germline DNA. Science. 2014; 345: 1184-8.
-
(2014)
Science.
, vol.345
, pp. 1184-1188
-
-
Long, C.1
McAnally, J.R.2
Shelton, J.M.3
Mireault, A.A.4
Bassel-Duby, R.5
Olson, E.N.6
-
25
-
-
0027137419
-
Loss of fumarylacetoacetate hydrolase is responsible for the neonatal hepatic dysfunction phenotype of lethal albino mice
-
Grompe M, al-Dhalimy M, Finegold M, Ou CN, Burlingame T, Kennaway NG, Soriano P. Loss of fumarylacetoacetate hydrolase is responsible for the neonatal hepatic dysfunction phenotype of lethal albino mice. Genes Dev. 1993; 7: 2298-307.
-
(1993)
Genes Dev.
, vol.7
, pp. 2298-2307
-
-
Grompe, M.1
Al-Dhalimy, M.2
Finegold, M.3
Ou, C.N.4
Burlingame, T.5
Kennaway, N.G.6
Soriano, P.7
-
26
-
-
0035895242
-
Point mutations in the murine fumarylacetoacetate hydrolase gene: Animal models for the human genetic disorder hereditary tyrosinemia type 1
-
Aponte JL, Sega GA, Hauser LJ, Dhar MS, Withrow CM, Carpenter DA, et al. Point mutations in the murine fumarylacetoacetate hydrolase gene: Animal models for the human genetic disorder hereditary tyrosinemia type 1. Proc Natl Acad Sci USA. 2001; 98: 641-5.
-
(2001)
Proc Natl Acad Sci USA.
, vol.98
, pp. 641-645
-
-
Aponte, J.L.1
Sega, G.A.2
Hauser, L.J.3
Dhar, M.S.4
Withrow, C.M.5
Carpenter, D.A.6
-
27
-
-
84960882884
-
Therapeutic genome editing by combined viral and non-viral delivery of CRISPR system components in vivo
-
Yin H, Song C-Q, Dorkin JR, Zhu LJ, Li Y, Wu Q, et al. Therapeutic genome editing by combined viral and non-viral delivery of CRISPR system components in vivo. Nat Biotechnol. 2016; 34: 328-33.
-
(2016)
Nat Biotechnol.
, vol.34
, pp. 328-333
-
-
Yin, H.1
Song, C.-Q.2
Dorkin, J.R.3
Zhu, L.J.4
Li, Y.5
Wu, Q.6
-
28
-
-
84984815990
-
Genome editing with CRISPR/Cas9 in postnatal mice corrects PRKAG2 cardiac syndrome
-
Xie C, Zhang Y-P, Song L, Luo J, Qi W, Hu J, et al. Genome editing with CRISPR/Cas9 in postnatal mice corrects PRKAG2 cardiac syndrome. Cell Res. 2016; 26: 1099-111.
-
(2016)
Cell Res.
, vol.26
, pp. 1099-1111
-
-
Xie, C.1
Zhang, Y.-P.2
Song, L.3
Luo, J.4
Qi, W.5
Hu, J.6
-
29
-
-
85013028996
-
Efficient in vivo gene editing using ribonucleoproteins in skin stem cells of recessive dystrophic epidermolysis bullosa mouse model
-
Wu W, Lu Z, Li F, Wang W, Qian N, Duan J, et al. Efficient in vivo gene editing using ribonucleoproteins in skin stem cells of recessive dystrophic epidermolysis bullosa mouse model. Proc Natl Acad Sci USA. 2017; 114: 1660-5.
-
(2017)
Proc Natl Acad Sci USA.
, vol.114
, pp. 1660-1665
-
-
Wu, W.1
Lu, Z.2
Li, F.3
Wang, W.4
Qian, N.5
Duan, J.6
-
30
-
-
84949211352
-
Large genomic fragment deletion and functional gene cassette knock-in via Cas9 protein mediated genome editing in one-cell rodent embryos
-
Wang L, Shao Y, Guan Y, Li L, Wu L, Chen F, et al. Large genomic fragment deletion and functional gene cassette knock-in via Cas9 protein mediated genome editing in one-cell rodent embryos. Sci Rep. 2015; 5: 17517.
-
(2015)
Sci Rep.
, vol.5
, pp. 17517
-
-
Wang, L.1
Shao, Y.2
Guan, Y.3
Li, L.4
Wu, L.5
Chen, F.6
-
31
-
-
84991764274
-
Microinjection-based generation of mutant mice with a double mutation and a 0. 5 Mb deletion in their genome by the CRISPR/Cas9 system
-
Hara S, Kato T, Goto Y, Kubota S, Tamano M, Terao M, Takada S. Microinjection-based generation of mutant mice with a double mutation and a 0. 5 Mb deletion in their genome by the CRISPR/Cas9 system. J Reprod Dev. 2016; 62: 531-6.
-
(2016)
J Reprod Dev.
, vol.62
, pp. 531-536
-
-
Hara, S.1
Kato, T.2
Goto, Y.3
Kubota, S.4
Tamano, M.5
Terao, M.6
Takada, S.7
-
32
-
-
85038959265
-
Creation of mutant mice with megabase-sized deletions containing custom-designed breakpoints by means of the CRISPR/Cas9 system
-
Kato T, Hara S, Goto Y, Ogawa Y, Okayasu H, Kubota S, et al. Creation of mutant mice with megabase-sized deletions containing custom-designed breakpoints by means of the CRISPR/Cas9 system. Sci Rep. 2017; 7: 1156.
-
(2017)
Sci Rep.
, vol.7
, pp. 1156
-
-
Kato, T.1
Hara, S.2
Goto, Y.3
Ogawa, Y.4
Okayasu, H.5
Kubota, S.6
-
33
-
-
84959375643
-
Chromosome engineering in zygotes with CRISPR/Cas9
-
Boroviak K, Doe B, Banerjee R, Yang F, Bradley A. Chromosome engineering in zygotes with CRISPR/Cas9. Genesis. 2016; 54: 78-85.
-
(2016)
Genesis.
, vol.54
, pp. 78-85
-
-
Boroviak, K.1
Doe, B.2
Banerjee, R.3
Yang, F.4
Bradley, A.5
-
34
-
-
85014746979
-
Efficient and rapid generation of large genomic variants in rats and mice using CRISMERE
-
Birling M-C, Schaeffer L, Andr P, Lindner L, Mar chal D, Ayadi A, et al. Efficient and rapid generation of large genomic variants in rats and mice using CRISMERE. Sci Rep. 2017; 7: 43331.
-
(2017)
Sci Rep.
, vol.7
, pp. 43331
-
-
Birling, M.-C.1
Schaeffer, L.2
Andr, P.3
Lindner, L.4
Mar chal, D.5
Ayadi, A.6
-
35
-
-
84923384373
-
Deletions, inversions, duplications: Engineering of structural variants using CRISPR/Cas in mice
-
Kraft K, Geuer S, Will AJ, Chan WL, Paliou C, Borschiwer M, et al. Deletions, inversions, duplications: engineering of structural variants using CRISPR/Cas in mice. Cell Rep. 2015; 10: 833-9.
-
(2015)
Cell Rep.
, vol.10
, pp. 833-839
-
-
Kraft, K.1
Geuer, S.2
Will, A.J.3
Chan, W.L.4
Paliou, C.5
Borschiwer, M.6
-
36
-
-
84955569113
-
SsODN-mediated knock-in with CRISPR-Cas for large genomic regions in zygotes
-
Yoshimi K, Kunihiro Y, Kaneko T, Nagahora H, Voigt B, Mashimo T. ssODN-mediated knock-in with CRISPR-Cas for large genomic regions in zygotes. Nat Commun. 2016; 7: 10431.
-
(2016)
Nat Commun.
, vol.7
, pp. 10431
-
-
Yoshimi, K.1
Kunihiro, Y.2
Kaneko, T.3
Nagahora, H.4
Voigt, B.5
Mashimo, T.6
|