Evolutionary Mechanisms Shaping the Maintenance of Antibiotic Resistance

Trends in Microbiology

Volumn 26, Issue 8, 2018, Pages 677-691

  Durão, Paulo ^a   Balbontín, Roberto ^a   Gordo, Isabel ^a  

^a INSTITUTO GULBENKIAN DE CIÊNCIA   (Portugal)

Author keywords

antibiotic; compensation; epistasis; evolution; fitness costs; multidrug resistance

Indexed keywords

AMINOGLYCOSIDE ANTIBIOTIC AGENT; CARBAPENEM; CEPHALOSPORIN; DNA TOPOISOMERASE (ATP HYDROLYSING) A; FOSFOMYCIN; OFLOXACIN; QUINOLINE DERIVED ANTIINFECTIVE AGENT; RIFAMPICIN; RNA POLYMERASE BETA SUBUNIT; STREPTOMYCIN; TETRACYCLINE; VANCOMYCIN; ANTIINFECTIVE AGENT;

ANTIBIOTIC RESISTANCE; ANTIBIOTIC SENSITIVITY; BACTERIAL GROWTH; BACTERIAL SURVIVAL; BACTERIAL VIRULENCE; CHROMOSOME MUTATION; EPISTASIS; ESCHERICHIA COLI; EVOLUTION; GENE DELETION; GENE DUPLICATION; GENE INSERTION; GENE REARRANGEMENT; GENETIC VARIATION; GENOTYPE ENVIRONMENT INTERACTION; GYRA GENE; HORIZONTAL GENE TRANSFER; MINIMUM INHIBITORY CONCENTRATION; MUTATION RATE; MYCOBACTERIUM SMEGMATIS; MYCOBACTERIUM TUBERCULOSIS; NATURAL SELECTION; NONHUMAN; NUSG GENE; PLEIOTROPY; PRIORITY JOURNAL; PSEUDOMONAS AERUGINOSA; REVIEW; RPOB GENE; RPSL GENE; SALMONELLA ENTERICA; STAPHYLOCOCCUS AUREUS; STREPTOCOCCUS PNEUMONIAE; THERMOSTABILITY; DRUG EFFECT; GENETICS; GROWTH, DEVELOPMENT AND AGING; MICROBIAL SENSITIVITY TEST; MULTIDRUG RESISTANCE; MUTATION; PHENOTYPE; REPRODUCTIVE FITNESS;

ANTI-BACTERIAL AGENTS; DRUG RESISTANCE, MULTIPLE, BACTERIAL; EPISTASIS, GENETIC; ESCHERICHIA COLI; GENETIC FITNESS; MICROBIAL SENSITIVITY TESTS; MUTATION; PHENOTYPE;

EID: 85044768181     PISSN: 0966842X     EISSN: 18784380     Source Type: Journal    
DOI: 10.1016/j.tim.2018.01.005     Document Type: Review

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