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Volumn 11, Issue 3, 2015, Pages 182-188

Collective antibiotic tolerance: Mechanisms, dynamics and intervention

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTIC AGENT; ANTIINFECTIVE AGENT;

EID: 84923353801     PISSN: 15524450     EISSN: 15524469     Source Type: Journal    
DOI: 10.1038/nchembio.1754     Document Type: Review
Times cited : (119)

References (93)
  • 1
    • 10944272743 scopus 로고    scopus 로고
    • Antibacterial resistance worldwide: Causes, challenges and responses
    • Levy, S.B. & Marshall, B. Antibacterial resistance worldwide: causes, challenges and responses. Nat. Med. 10, S122-S129 (2004).
    • (2004) Nat. Med. , vol.10 , pp. S122-S129
    • Levy, S.B.1    Marshall, B.2
  • 2
    • 0242291985 scopus 로고    scopus 로고
    • Why is big Pharma getting out of antibacterial drug discovery?
    • Projan, S.J. Why is big Pharma getting out of antibacterial drug discovery? Curr. Opin. Microbiol. 6, 427-430 (2003).
    • (2003) Curr. Opin. Microbiol. , vol.6 , pp. 427-430
    • Projan, S.J.1
  • 3
    • 33745238716 scopus 로고    scopus 로고
    • Antimicrobial stewardship
    • Fishman, N. Antimicrobial stewardship. Am. J. Infect. Control 34, S55-S63 (2006).
    • (2006) Am. J. Infect. Control , vol.34 , pp. S55-S63
    • Fishman, N.1
  • 4
    • 77957980707 scopus 로고    scopus 로고
    • Origins and evolution of antibiotic resistance
    • Davies, J. & Davies, D. Origins and evolution of antibiotic resistance. Microbiol. Mol. Biol. Rev. 74, 417-433 (2010).
    • (2010) Microbiol. Mol. Biol. Rev. , vol.74 , pp. 417-433
    • Davies, J.1    Davies, D.2
  • 5
  • 6
    • 33845607284 scopus 로고    scopus 로고
    • Persister cells, dormancy and infectious disease
    • Lewis, K. Persister cells, dormancy and infectious disease. Nat. Rev. Microbiol. 5, 48-56 (2007).
    • (2007) Nat. Rev. Microbiol. , vol.5 , pp. 48-56
    • Lewis, K.1
  • 7
    • 84873485631 scopus 로고    scopus 로고
    • Pharmacodynamics, population dynamics, and the evolution of persistence in Staphylococcus aureus
    • Johnson, P.J. & Levin, B.R. Pharmacodynamics, population dynamics, and the evolution of persistence in Staphylococcus aureus. PLoS Genet. 9, e1003123 (2013).
    • (2013) PLoS Genet. , vol.9
    • Johnson, P.J.1    Levin, B.R.2
  • 10
    • 84868282596 scopus 로고    scopus 로고
    • The inoculum effect and band-pass bacterial response to periodic antibiotic treatment
    • Tan, C. et al. The inoculum effect and band-pass bacterial response to periodic antibiotic treatment. Mol. Syst. Biol. 8, 617 (2012).
    • (2012) Mol. Syst. Biol. , vol.8 , pp. 617
    • Tan, C.1
  • 11
    • 77953206694 scopus 로고    scopus 로고
    • Indole as an intercellular signal in microbial communities
    • Lee, J.H. & Lee, J. Indole as an intercellular signal in microbial communities. FEMS Microbiol. Rev. 34, 426-444 (2010).
    • (2010) FEMS Microbiol. Rev. , vol.34 , pp. 426-444
    • Lee, J.H.1    Lee, J.2
  • 12
    • 77956280046 scopus 로고    scopus 로고
    • An environment-sensitive synthetic microbial ecosystem
    • Hu, B., Du, J., Zou, R.-y. & Yuan, Y.-j. An environment-sensitive synthetic microbial ecosystem. PLoS ONE 5, e10619 (2010).
    • (2010) PLoS ONE , vol.5
    • Hu, B.1    Du, J.2    Zou, R.-Y.3    Yuan, Y.-J.4
  • 13
    • 84878457598 scopus 로고    scopus 로고
    • Programmed cell death in bacteria and implications for antibiotic therapy
    • Tanouchi, Y., Lee, A.J., Meredith, H. & You, L. Programmed cell death in bacteria and implications for antibiotic therapy. Trends Microbiol. 21, 265-270 (2013).
    • (2013) Trends Microbiol. , vol.21 , pp. 265-270
    • Tanouchi, Y.1    Lee, A.J.2    Meredith, H.3    You, L.4
  • 15
    • 0035189967 scopus 로고    scopus 로고
    • Cefepime, piperacillin-tazobactam, and the inoculum effect in tests with extended-spectrum β-lactamase-producing Enterobacteriaceae
    • Thomson, K.S. & Moland, E.S. Cefepime, piperacillin-tazobactam, and the inoculum effect in tests with extended-spectrum β-lactamase-producing Enterobacteriaceae. Antimicrob. Agents Chemother. 45, 3548-3554 (2001).
    • (2001) Antimicrob. Agents Chemother. , vol.45 , pp. 3548-3554
    • Thomson, K.S.1    Moland, E.S.2
  • 16
    • 0017208308 scopus 로고
    • The β-lactamases of gram-negative bacteria and their role in resistance to β-lactam antibiotics
    • Sykes, R.B. & Matthew, M. The β-lactamases of gram-negative bacteria and their role in resistance to β-lactam antibiotics. J. Antimicrob. Chemother. 2, 115-157 (1976).
    • (1976) J. Antimicrob. Chemother. , vol.2 , pp. 115-157
    • Sykes, R.B.1    Matthew, M.2
  • 17
    • 58149151397 scopus 로고    scopus 로고
    • The communication factor EDF and the toxin-antitoxin module mazEF determine the mode of action of antibiotics
    • Kolodkin-Gal, I., Sat, B., Keshet, A. & Engelberg-Kulka, H. The communication factor EDF and the toxin-antitoxin module mazEF determine the mode of action of antibiotics. PLoS Biol. 6, e319 (2008).
    • (2008) PLoS Biol. , vol.6 , pp. e319
    • Kolodkin-Gal, I.1    Sat, B.2    Keshet, A.3    Engelberg-Kulka, H.4
  • 19
    • 77955786950 scopus 로고    scopus 로고
    • Different classes of antibiotics differentially influence Shiga toxin production
    • McGannon, C.M., Fuller, C.A. & Weiss, A.A. Different classes of antibiotics differentially influence Shiga toxin production. Antimicrob. Agents Chemother. 54, 3790-3798 (2010).
    • (2010) Antimicrob. Agents Chemother. , vol.54 , pp. 3790-3798
    • McGannon, C.M.1    Fuller, C.A.2    Weiss, A.A.3
  • 20
    • 0033056680 scopus 로고    scopus 로고
    • Sequence of Shiga toxin 2 phage 933W from Escherichia coli O157: H7: Shiga toxin as a phage late-gene product
    • Plunkett, G., Rose, D.J., Durfee, T.J. & Blattner, F.R. Sequence of Shiga toxin 2 phage 933W from Escherichia coli O157: H7: Shiga toxin as a phage late-gene product. J. Bacteriol. 181, 1767-1778 (1999).
    • (1999) J. Bacteriol. , vol.181 , pp. 1767-1778
    • Plunkett, G.1    Rose, D.J.2    Durfee, T.J.3    Blattner, F.R.4
  • 21
    • 67749090881 scopus 로고    scopus 로고
    • Shiga toxin as a bacterial defense against a eukaryotic predator, Tetrahymena thermophila
    • Lainhart, W., Stolfa, G. & Koudelka, G.B. Shiga toxin as a bacterial defense against a eukaryotic predator, Tetrahymena thermophila. J. Bacteriol. 191, 5116-5122 (2009).
    • (2009) J. Bacteriol. , vol.191 , pp. 5116-5122
    • Lainhart, W.1    Stolfa, G.2    Koudelka, G.B.3
  • 23
    • 0141707658 scopus 로고    scopus 로고
    • Quorum sensing controls biofilm formation in Vibrio cholerae
    • Hammer, B.K. & Bassler, B.L. Quorum sensing controls biofilm formation in Vibrio cholerae. Mol. Microbiol. 50, 101-104 (2003).
    • (2003) Mol. Microbiol. , vol.50 , pp. 101-104
    • Hammer, B.K.1    Bassler, B.L.2
  • 24
    • 84870372913 scopus 로고    scopus 로고
    • Optimality and robustness in quorum sensing (QS)-mediated regulation of a costly public good enzyme
    • Pai, A., Tanouchi, Y. & You, L. Optimality and robustness in quorum sensing (QS)-mediated regulation of a costly public good enzyme. Proc. Natl. Acad. Sci. USA 109, 19810-19815 (2012).
    • (2012) Proc. Natl. Acad. Sci. USA , vol.109 , pp. 19810-19815
    • Pai, A.1    Tanouchi, Y.2    You, L.3
  • 25
    • 30044445411 scopus 로고    scopus 로고
    • Fluoroquinolone-modifying enzyme: A new adaptation of a common aminoglycoside acetyltransferase
    • Robicsek, A. et al. Fluoroquinolone-modifying enzyme: a new adaptation of a common aminoglycoside acetyltransferase. Nat. Med. 12, 83-88 (2006).
    • (2006) Nat. Med. , vol.12 , pp. 83-88
    • Robicsek, A.1
  • 26
    • 0035282402 scopus 로고    scopus 로고
    • Role of SspA in the density-dependent expression of the transcriptional activator AarP in Providencia stuartii
    • Ding, X., Baca-DeLancey, R.R. & Rather, P.N. Role of SspA in the density-dependent expression of the transcriptional activator AarP in Providencia stuartii. FEMS Microbiol. Lett. 196, 25-29 (2001).
    • (2001) FEMS Microbiol. Lett. , vol.196 , pp. 25-29
    • Ding, X.1    Baca-Delancey, R.R.2    Rather, P.N.3
  • 27
    • 15944414231 scopus 로고    scopus 로고
    • Quorum sensing: The power of cooperation in the world of Pseudomonas
    • Juhas, M., Eberl, L. & Tümmler, B. Quorum sensing: the power of cooperation in the world of Pseudomonas. Environ. Microbiol. 7, 459-471 (2005).
    • (2005) Environ. Microbiol. , vol.7 , pp. 459-471
    • Juhas, M.1    Eberl, L.2    Tümmler, B.3
  • 28
    • 0032502811 scopus 로고    scopus 로고
    • The involvement of cell-to-cell signals in the development of a bacterial biofilm
    • Davies, D.G. et al. The involvement of cell-to-cell signals in the development of a bacterial biofilm. Science 280, 295-298 (1998).
    • (1998) Science , vol.280 , pp. 295-298
    • Davies, D.G.1
  • 29
    • 0031861798 scopus 로고    scopus 로고
    • In vitro and in vivo activities of levofloxacin against biofilm-producing Pseudomonas aeruginosa
    • Ishida, H. et al. In vitro and in vivo activities of levofloxacin against biofilm-producing Pseudomonas aeruginosa. Antimicrob. Agents Chemother. 42, 1641-1645 (1998).
    • (1998) Antimicrob. Agents Chemother. , vol.42 , pp. 1641-1645
    • Ishida, H.1
  • 30
    • 77955593345 scopus 로고    scopus 로고
    • Penetration of antibiotics through Staphylococcus aureus and Staphylococcus epidermidis biofilms
    • Singh, R., Ray, P., Das, A. & Sharma, M. Penetration of antibiotics through Staphylococcus aureus and Staphylococcus epidermidis biofilms. J. Antimicrob. Chemother. 65, 1955-1958 (2010).
    • (2010) J. Antimicrob. Chemother. , vol.65 , pp. 1955-1958
    • Singh, R.1    Ray, P.2    Das, A.3    Sharma, M.4
  • 31
    • 0033930831 scopus 로고    scopus 로고
    • Role of antibiotic penetration limitation in Klebsiella pneumoniae biofilm resistance to ampicillin and ciprofloxacin
    • Anderl, J.N., Franklin, M.J. & Stewart, P.S. Role of antibiotic penetration limitation in Klebsiella pneumoniae biofilm resistance to ampicillin and ciprofloxacin. Antimicrob. Agents Chemother. 44, 1818-1824 (2000).
    • (2000) Antimicrob. Agents Chemother. , vol.44 , pp. 1818-1824
    • Anderl, J.N.1    Franklin, M.J.2    Stewart, P.S.3
  • 33
    • 0033591467 scopus 로고    scopus 로고
    • Bacterial biofilms: A common cause of persistent infections
    • Costerton, J.W., Stewart, P.S. & Greenberg, E. Bacterial biofilms: a common cause of persistent infections. Science 284, 1318-1322 (1999).
    • (1999) Science , vol.284 , pp. 1318-1322
    • Costerton, J.W.1    Stewart, P.S.2    Greenberg, E.3
  • 35
    • 62549089300 scopus 로고    scopus 로고
    • Functional relationship between bacterial cell density and the efficacy of antibiotics
    • Udekwu, K.I., Parrish, N., Ankomah, P., Baquero, F. & Levin, B.R. Functional relationship between bacterial cell density and the efficacy of antibiotics. J. Antimicrob. Chemother. 63, 745-757 (2009).
    • (2009) J. Antimicrob. Chemother. , vol.63 , pp. 745-757
    • Udekwu, K.I.1    Parrish, N.2    Ankomah, P.3    Baquero, F.4    Levin, B.R.5
  • 36
    • 44949162900 scopus 로고    scopus 로고
    • A coarse-grained biophysical model of E. Coli and its application to perturbation of the rRNA operon copy number
    • Tadmor, A.D. & Tlusty, T. A coarse-grained biophysical model of E. coli and its application to perturbation of the rRNA operon copy number. PLoS Comput. Biol. 4, e1000038 (2008).
    • (2008) PLoS Comput. Biol. , vol.4
    • Tadmor, A.D.1    Tlusty, T.2
  • 37
    • 0030767422 scopus 로고    scopus 로고
    • Bistable biochemical switching and the control of the events of the cell cycle
    • Thron, C. Bistable biochemical switching and the control of the events of the cell cycle. Oncogene 15, 317-325 (1997).
    • (1997) Oncogene , vol.15 , pp. 317-325
    • Thron, C.1
  • 38
    • 0025328743 scopus 로고
    • Ribosomes as sensors of heat and cold shock in Escherichia coli
    • VanBogelen, R.A. & Neidhardt, F.C. Ribosomes as sensors of heat and cold shock in Escherichia coli. Proc. Natl. Acad. Sci. USA 87, 5589-5593 (1990).
    • (1990) Proc. Natl. Acad. Sci. USA , vol.87 , pp. 5589-5593
    • Vanbogelen, R.A.1    Neidhardt, F.C.2
  • 39
    • 77957754593 scopus 로고    scopus 로고
    • Quantitative proteomic analysis of ribosome assembly and turnover in vivo
    • Sykes, M.T., Shajani, Z., Sperling, E., Beck, A.H. & Williamson, J.R. Quantitative proteomic analysis of ribosome assembly and turnover in vivo. J. Mol. Biol. 403, 331-345 (2010).
    • (2010) J. Mol. Biol. , vol.403 , pp. 331-345
    • Sykes, M.T.1    Shajani, Z.2    Sperling, E.3    Beck, A.H.4    Williamson, J.R.5
  • 40
    • 0037386391 scopus 로고    scopus 로고
    • The Staphylococcus aureus cidAB operon: Evaluation of its role in regulation of murein hydrolase activity and penicillin tolerance
    • Rice, K.C. et al. The Staphylococcus aureus cidAB operon: evaluation of its role in regulation of murein hydrolase activity and penicillin tolerance. J. Bacteriol. 185, 2635-2643 (2003).
    • (2003) J. Bacteriol. , vol.185 , pp. 2635-2643
    • Rice, K.C.1
  • 41
    • 34249950498 scopus 로고    scopus 로고
    • The cidA murein hydrolase regulator contributes to DNA release and biofilm development in Staphylococcus aureus
    • Rice, K.C. et al. The cidA murein hydrolase regulator contributes to DNA release and biofilm development in Staphylococcus aureus. Proc. Natl. Acad. Sci. USA 104, 8113-8118 (2007).
    • (2007) Proc. Natl. Acad. Sci. USA , vol.104 , pp. 8113-8118
    • Rice, K.C.1
  • 42
    • 34548008613 scopus 로고    scopus 로고
    • The biological role of death and lysis in biofilm development
    • Bayles, K.W. The biological role of death and lysis in biofilm development. Nat. Rev. Microbiol. 5, 721-726 (2007).
    • (2007) Nat. Rev. Microbiol. , vol.5 , pp. 721-726
    • Bayles, K.W.1
  • 43
    • 0034065895 scopus 로고    scopus 로고
    • The Staphylococcus aureus lrgAB operon modulates murein hydrolase activity and penicillin tolerance
    • Groicher, K.H., Firek, B.A., Fujimoto, D.F. & Bayles, K.W. The Staphylococcus aureus lrgAB operon modulates murein hydrolase activity and penicillin tolerance. J. Bacteriol. 182, 1794-1801 (2000).
    • (2000) J. Bacteriol. , vol.182 , pp. 1794-1801
    • Groicher, K.H.1    Firek, B.A.2    Fujimoto, D.F.3    Bayles, K.W.4
  • 44
    • 0033758742 scopus 로고    scopus 로고
    • Swarming of Pseudomonas aeruginosa is dependent on cell-to-cell signaling and requires flagella and pili
    • Köhler, T., Curty, L.K., Barja, F., van Delden, C. & Pechère, J.-C. Swarming of Pseudomonas aeruginosa is dependent on cell-to-cell signaling and requires flagella and pili. J. Bacteriol. 182, 5990-5996 (2000).
    • (2000) J. Bacteriol. , vol.182 , pp. 5990-5996
    • Köhler, T.1    Curty, L.K.2    Barja, F.3    Van Delden, C.4    Pechère, J.-C.5
  • 45
    • 77649268551 scopus 로고    scopus 로고
    • Cell density and mobility protect swarming bacteria against antibiotics
    • Butler, M.T., Wang, Q. & Harshey, R.M. Cell density and mobility protect swarming bacteria against antibiotics. Proc. Natl. Acad. Sci. USA 107, 3776-3781 (2010).
    • (2010) Proc. Natl. Acad. Sci. USA , vol.107 , pp. 3776-3781
    • Butler, M.T.1    Wang, Q.2    Harshey, R.M.3
  • 46
    • 0038643291 scopus 로고    scopus 로고
    • Swarm-cell differentiation in Salmonella enterica serovar Typhimurium results in elevated resistance to multiple antibiotics
    • Kim, W., Killam, T., Sood, V. & Surette, M.G. Swarm-cell differentiation in Salmonella enterica serovar Typhimurium results in elevated resistance to multiple antibiotics. J. Bacteriol. 185, 3111-3117 (2003).
    • (2003) J. Bacteriol. , vol.185 , pp. 3111-3117
    • Kim, W.1    Killam, T.2    Sood, V.3    Surette, M.G.4
  • 47
    • 53049084283 scopus 로고    scopus 로고
    • Living on a surface: Swarming and biofilm formation
    • Verstraeten, N. et al. Living on a surface: swarming and biofilm formation. Trends Microbiol. 16, 496-506 (2008).
    • (2008) Trends Microbiol. , vol.16 , pp. 496-506
    • Verstraeten, N.1
  • 48
    • 84883269888 scopus 로고    scopus 로고
    • Convergent evolution of hyperswarming leads to impaired biofilm formation in pathogenic bacteria
    • van Ditmarsch, D. et al. Convergent evolution of hyperswarming leads to impaired biofilm formation in pathogenic bacteria. Cell Reports 4, 697-708 (2013).
    • (2013) Cell Reports , vol.4 , pp. 697-708
    • Van Ditmarsch, D.1
  • 49
    • 41949114474 scopus 로고    scopus 로고
    • Swarming of Pseudomonas aeruginosa is a complex adaptation leading to increased production of virulence factors and antibiotic resistance
    • Overhage, J., Bains, M., Brazas, M.D. & Hancock, R.E. Swarming of Pseudomonas aeruginosa is a complex adaptation leading to increased production of virulence factors and antibiotic resistance. J. Bacteriol. 190, 2671-2679 (2008).
    • (2008) J. Bacteriol. , vol.190 , pp. 2671-2679
    • Overhage, J.1    Bains, M.2    Brazas, M.D.3    Hancock, R.E.4
  • 50
    • 0034985868 scopus 로고    scopus 로고
    • Bacterial modification of LPS and resistance to antimicrobial peptides
    • Gunn, J.S. Bacterial modification of LPS and resistance to antimicrobial peptides. J. Endotoxin Res. 7, 57-62 (2001).
    • (2001) J. Endotoxin Res. , vol.7 , pp. 57-62
    • Gunn, J.S.1
  • 51
    • 77956328000 scopus 로고    scopus 로고
    • Bacterial charity work leads to population-wide resistance
    • Lee, H.H., Molla, M.N., Cantor, C.R. & Collins, J.J. Bacterial charity work leads to population-wide resistance. Nature 467, 82-85 (2010).
    • (2010) Nature , vol.467 , pp. 82-85
    • Lee, H.H.1    Molla, M.N.2    Cantor, C.R.3    Collins, J.J.4
  • 52
    • 0035140586 scopus 로고    scopus 로고
    • Gfp-based N-acyl homoserine-lactone sensor systems for detection of bacterial communication
    • Andersen, J.B. et al. gfp-based N-acyl homoserine-lactone sensor systems for detection of bacterial communication. Appl. Environ. Microbiol. 67, 575-585 (2001).
    • (2001) Appl. Environ. Microbiol. , vol.67 , pp. 575-585
    • Andersen, J.B.1
  • 54
    • 0026440223 scopus 로고
    • Effect of polysaccharide interactions on antibiotic susceptibility of Pseudomonas aeruginosa
    • Allison, D.G. & Matthews, M. Effect of polysaccharide interactions on antibiotic susceptibility of Pseudomonas aeruginosa. J. Appl. Bacteriol. 73, 484-488 (1992).
    • (1992) J. Appl. Bacteriol. , vol.73 , pp. 484-488
    • Allison, D.G.1    Matthews, M.2
  • 55
    • 0032737310 scopus 로고    scopus 로고
    • Efficacy of antibiotic therapy for infection with Shiga-like toxin-producing Escherichia coli O157: H7 in mice with protein-calorie malnutrition
    • Kurioka, T., Yunou, Y., Harada, H. & Kita, E. Efficacy of antibiotic therapy for infection with Shiga-like toxin-producing Escherichia coli O157: H7 in mice with protein-calorie malnutrition. Eur. J. Clin. Microbiol. Infect. Dis. 18, 561-571 (1999).
    • (1999) Eur. J. Clin. Microbiol. Infect. Dis. , vol.18 , pp. 561-571
    • Kurioka, T.1    Yunou, Y.2    Harada, H.3    Kita, E.4
  • 56
    • 0029017723 scopus 로고
    • Combination effect of fosfomycin and ofloxacin against Pseudomonas aeruginosa growing in a biofilm
    • Kumon, H., Ono, N., Iida, M. & Nickel, J.C. Combination effect of fosfomycin and ofloxacin against Pseudomonas aeruginosa growing in a biofilm. Antimicrob. Agents Chemother. 39, 1038-1044 (1995).
    • (1995) Antimicrob. Agents Chemother. , vol.39 , pp. 1038-1044
    • Kumon, H.1    Ono, N.2    Iida, M.3    Nickel, J.C.4
  • 57
    • 77958021478 scopus 로고    scopus 로고
    • Biofilm maturity studies indicate sharp debridement opens a time-dependent therapeutic window
    • Wolcott, R.D. et al. Biofilm maturity studies indicate sharp debridement opens a time-dependent therapeutic window. J. Wound Care 19, 320-328 (2010).
    • (2010) J. Wound Care , vol.19 , pp. 320-328
    • Wolcott, R.D.1
  • 58
  • 59
    • 74249108028 scopus 로고    scopus 로고
    • Three decades of β-lactamase inhibitors
    • Drawz, S.M. & Bonomo, R.A. Three decades of β-lactamase inhibitors. Clin. Microbiol. Rev. 23, 160-201 (2010).
    • (2010) Clin. Microbiol. Rev. , vol.23 , pp. 160-201
    • Drawz, S.M.1    Bonomo, R.A.2
  • 60
    • 0343686104 scopus 로고    scopus 로고
    • Inhibitor-resistant TEM β-lactamases: Phenotypic, genetic and biochemical characteristics
    • Chaïbi, E.B., Sirot, D., Paul, G. & Labia, R. Inhibitor-resistant TEM β-lactamases: phenotypic, genetic and biochemical characteristics. J. Antimicrob. Chemother. 43, 447-458 (1999).
    • (1999) J. Antimicrob. Chemother. , vol.43 , pp. 447-458
    • Chaïbi, E.B.1    Sirot, D.2    Paul, G.3    Labia, R.4
  • 61
    • 84655169530 scopus 로고    scopus 로고
    • E/ systems: Their role in resistance, virulence, and their potential for antibiotic development
    • Mutschler, H. & Meinhart, A. e/ systems: their role in resistance, virulence, and their potential for antibiotic development. J. Mol. Med. 89, 1183-1194 (2011).
    • (2011) J. Mol. Med. , vol.89 , pp. 1183-1194
    • Mutschler, H.1    Meinhart, A.2
  • 62
    • 73049085016 scopus 로고    scopus 로고
    • A toxin-antitoxin module as a target for antimicrobial development
    • Lioy, V.S., Rey, O., Balsa, D., Pellicer, T. & Alonso, J.C. A toxin-antitoxin module as a target for antimicrobial development. Plasmid 63, 31-39 (2010).
    • (2010) Plasmid , vol.63 , pp. 31-39
    • Lioy, V.S.1    Rey, O.2    Balsa, D.3    Pellicer, T.4    Alonso, J.C.5
  • 63
    • 0024322485 scopus 로고
    • Contribution of autolysin to virulence of Streptococcus pneumoniae
    • Berry, A.M., Lock, R.A., Hansman, D. & Paton, J.C. Contribution of autolysin to virulence of Streptococcus pneumoniae. Infect. Immun. 57, 2324-2330 (1989).
    • (1989) Infect. Immun. , vol.57 , pp. 2324-2330
    • Berry, A.M.1    Lock, R.A.2    Hansman, D.3    Paton, J.C.4
  • 64
    • 84870835870 scopus 로고    scopus 로고
    • Programming stress-induced altruistic death in engineered bacteria
    • Tanouchi, Y., Pai, A., Buchler, N.E. & You, L. Programming stress-induced altruistic death in engineered bacteria. Mol. Syst. Biol. 8, 626 (2012).
    • (2012) Mol. Syst. Biol. , vol.8 , pp. 626
    • Tanouchi, Y.1    Pai, A.2    Buchler, N.E.3    You, L.4
  • 65
    • 0035007794 scopus 로고    scopus 로고
    • Azithromycin inhibits quorum sensing in Pseudomonas aeruginosa
    • Tateda, K. et al. Azithromycin inhibits quorum sensing in Pseudomonas aeruginosa. Antimicrob. Agents Chemother. 45, 1930-1933 (2001).
    • (2001) Antimicrob. Agents Chemother. , vol.45 , pp. 1930-1933
    • Tateda, K.1
  • 66
    • 84862641805 scopus 로고    scopus 로고
    • Azithromycin to prevent Pseudomonas aeruginosa ventilator-associated pneumonia by inhibition of quorum sensing: A randomized controlled trial
    • van Delden, C. et al. Azithromycin to prevent Pseudomonas aeruginosa ventilator-associated pneumonia by inhibition of quorum sensing: a randomized controlled trial. Intensive Care Med. 38, 1118-1125 (2012).
    • (2012) Intensive Care Med. , vol.38 , pp. 1118-1125
    • Van Delden, C.1
  • 67
    • 0034724191 scopus 로고    scopus 로고
    • AiiA, an enzyme that inactivates the acylhomoserine lactone quorum-sensing signal and attenuates the virulence of Erwinia carotovora
    • Dong, Y.-H., Xu, J.-L., Li, X.-Z. & Zhang, L.-H. AiiA, an enzyme that inactivates the acylhomoserine lactone quorum-sensing signal and attenuates the virulence of Erwinia carotovora. Proc. Natl. Acad. Sci. USA 97, 3526-3531 (2000).
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , pp. 3526-3531
    • Dong, Y.-H.1    Xu, J.-L.2    Li, X.-Z.3    Zhang, L.-H.4
  • 68
    • 84887034499 scopus 로고    scopus 로고
    • A quorum-sensing inhibitor blocks Pseudomonas aeruginosa virulence and biofilm formation
    • O'Loughlin, C.T. et al. A quorum-sensing inhibitor blocks Pseudomonas aeruginosa virulence and biofilm formation. Proc. Natl. Acad. Sci. USA 110, 17981-17986 (2013).
    • (2013) Proc. Natl. Acad. Sci. USA , vol.110 , pp. 17981-17986
    • O'loughlin, C.T.1
  • 69
    • 79956311555 scopus 로고    scopus 로고
    • Quorum sensing inhibitors increase the susceptibility of bacterial biofilms to antibiotics in vitro and in vivo
    • Brackman, G., Cos, P., Maes, L., Nelis, H.J. & Coenye, T. Quorum sensing inhibitors increase the susceptibility of bacterial biofilms to antibiotics in vitro and in vivo. Antimicrob. Agents Chemother. 55, 2655-2661 (2011).
    • (2011) Antimicrob. Agents Chemother. , vol.55 , pp. 2655-2661
    • Brackman, G.1    Cos, P.2    Maes, L.3    Nelis, H.J.4    Coenye, T.5
  • 70
    • 33746692516 scopus 로고    scopus 로고
    • Bacterial neuraminidase facilitates mucosal infection by participating in biofilm production
    • Soong, G. et al. Bacterial neuraminidase facilitates mucosal infection by participating in biofilm production. J. Clin. Invest. 116, 2297-2305 (2006).
    • (2006) J. Clin. Invest. , vol.116 , pp. 2297-2305
    • Soong, G.1
  • 71
    • 0036233697 scopus 로고    scopus 로고
    • 30S ribosomal subunit assembly is a target for inhibition by aminoglycosides in Escherichia coli
    • Mehta, R. & Champney, W.S. 30S ribosomal subunit assembly is a target for inhibition by aminoglycosides in Escherichia coli. Antimicrob. Agents Chemother. 46, 1546-1549 (2002).
    • (2002) Antimicrob. Agents Chemother. , vol.46 , pp. 1546-1549
    • Mehta, R.1    Champney, W.S.2
  • 72
    • 84899505083 scopus 로고    scopus 로고
    • Molecular mechanisms underlying bacterial persisters
    • Maisonneuve, E. & Gerdes, K. Molecular mechanisms underlying bacterial persisters. Cell 157, 539-548 (2014).
    • (2014) Cell , vol.157 , pp. 539-548
    • Maisonneuve, E.1    Gerdes, K.2
  • 74
    • 34548213103 scopus 로고    scopus 로고
    • A common mechanism of cellular death induced by bactericidal antibiotics
    • Kohanski, M.A., Dwyer, D.J., Hayete, B., Lawrence, C.A. & Collins, J.J. A common mechanism of cellular death induced by bactericidal antibiotics. Cell 130, 797-810 (2007).
    • (2007) Cell , vol.130 , pp. 797-810
    • Kohanski, M.A.1    Dwyer, D.J.2    Hayete, B.3    Lawrence, C.A.4    Collins, J.J.5
  • 75
    • 0033754263 scopus 로고    scopus 로고
    • Genetics of swarming motility in Salmonella enterica serovar Typhimurium: Critical role for lipopolysaccharide
    • Toguchi, A., Siano, M., Burkart, M. & Harshey, R.M. Genetics of swarming motility in Salmonella enterica serovar Typhimurium: critical role for lipopolysaccharide. J. Bacteriol. 182, 6308-6321 (2000).
    • (2000) J. Bacteriol. , vol.182 , pp. 6308-6321
    • Toguchi, A.1    Siano, M.2    Burkart, M.3    Harshey, R.M.4
  • 76
    • 0034816471 scopus 로고    scopus 로고
    • Salmonella enterica serovar typhimurium swarming mutants with altered biofilm-forming abilities: Surfactin inhibits biofilm formation
    • Mireles, J.R., Toguchi, A. & Harshey, R.M. Salmonella enterica serovar typhimurium swarming mutants with altered biofilm-forming abilities: surfactin inhibits biofilm formation. J. Bacteriol. 183, 5848-5854 (2001).
    • (2001) J. Bacteriol. , vol.183 , pp. 5848-5854
    • Mireles, J.R.1    Toguchi, A.2    Harshey, R.M.3
  • 77
    • 0021068344 scopus 로고
    • In-vivo protection of group A β-haemolytic streptococci from penicillin by β-lactamase-producing Bacteroides species
    • Brook, I., Pazzaglia, G., Coolbaugh, J.C. & Walker, R.I. In-vivo protection of group A β-haemolytic streptococci from penicillin by β-lactamase-producing Bacteroides species. J. Antimicrob. Chemother. 12, 599-606 (1983).
    • (1983) J. Antimicrob. Chemother. , vol.12 , pp. 599-606
    • Brook, I.1    Pazzaglia, G.2    Coolbaugh, J.C.3    Walker, R.I.4
  • 78
    • 84983208863 scopus 로고    scopus 로고
    • Sequence-specific antimicrobials using efficiently delivered RNA-guided nucleases
    • Citorik, R.J., Mimee, M. & Lu, T.K. Sequence-specific antimicrobials using efficiently delivered RNA-guided nucleases. Nat. Biotechnol. 32, 1141-1145 (2014).
    • (2014) Nat. Biotechnol. , vol.32 , pp. 1141-1145
    • Citorik, R.J.1    Mimee, M.2    Lu, T.K.3
  • 79
    • 84983142945 scopus 로고    scopus 로고
    • Exploiting CRISPR-Cas nucleases to produce sequence-specific antimicrobials
    • Bikard, D. et al. Exploiting CRISPR-Cas nucleases to produce sequence-specific antimicrobials. Nat. Biotechnol. 32, 1146-1150 (2014).
    • (2014) Nat. Biotechnol. , vol.32 , pp. 1146-1150
    • Bikard, D.1
  • 80
    • 0002753264 scopus 로고
    • The rate of bactericidal action of penicillin in vitro as a function of its concentration, and its paradoxically reduced activity at high concentrations against certain organisms
    • Eagle, H. & Musselman, A.D. The rate of bactericidal action of penicillin in vitro as a function of its concentration, and its paradoxically reduced activity at high concentrations against certain organisms. J. Exp. Med. 88, 99-131 (1948).
    • (1948) J. Exp. Med. , vol.88 , pp. 99-131
    • Eagle, H.1    Musselman, A.D.2
  • 81
    • 0041989633 scopus 로고    scopus 로고
    • Attenuation of Pseudomonas aeruginosa virulence by quorum sensing inhibitors
    • Hentzer, M. et al. Attenuation of Pseudomonas aeruginosa virulence by quorum sensing inhibitors. EMBO J. 22, 3803-3815 (2003).
    • (2003) EMBO J. , vol.22 , pp. 3803-3815
    • Hentzer, M.1
  • 82
    • 0348230962 scopus 로고    scopus 로고
    • Pharmacological inhibition of quorum sensing for the treatment of chronic bacterial infections
    • Hentzer, M. & Givskov, M. Pharmacological inhibition of quorum sensing for the treatment of chronic bacterial infections. J. Clin. Invest. 112, 1300-1307 (2003).
    • (2003) J. Clin. Invest. , vol.112 , pp. 1300-1307
    • Hentzer, M.1    Givskov, M.2
  • 83
    • 77954053982 scopus 로고    scopus 로고
    • Quorum sensing inhibition selects for virulence and cooperation in Pseudomonas aeruginosa
    • Köhler, T., Perron, G.G., Buckling, A. & Van Delden, C. Quorum sensing inhibition selects for virulence and cooperation in Pseudomonas aeruginosa. PLoS Pathog. 6, e1000883 (2010).
    • (2010) PLoS Pathog. , vol.6
    • Köhler, T.1    Perron, G.G.2    Buckling, A.3    Van Delden, C.4
  • 84
    • 33646452555 scopus 로고    scopus 로고
    • Quorum-sensing antagonistic activities of azithromycin in Pseudomonas aeruginosa PAO1: A global approach
    • Nalca, Y. et al. Quorum-sensing antagonistic activities of azithromycin in Pseudomonas aeruginosa PAO1: a global approach. Antimicrob. Agents Chemother. 50, 1680-1688 (2006).
    • (2006) Antimicrob. Agents Chemother. , vol.50 , pp. 1680-1688
    • Nalca, Y.1
  • 87
    • 22544468106 scopus 로고    scopus 로고
    • Multicellular organization in bacteria as a target for drug therapy
    • André, J.B. & Godelle, B. Multicellular organization in bacteria as a target for drug therapy. Ecol. Lett. 8, 800-810 (2005).
    • (2005) Ecol. Lett. , vol.8 , pp. 800-810
    • André, J.B.1    Godelle, B.2
  • 88
    • 84867298894 scopus 로고    scopus 로고
    • Bacterial quorum sensing and metabolic incentives to cooperate
    • Dandekar, A.A., Chugani, S. & Greenberg, E.P. Bacterial quorum sensing and metabolic incentives to cooperate. Science 338, 264-266 (2012).
    • (2012) Science , vol.338 , pp. 264-266
    • Dandekar, A.A.1    Chugani, S.2    Greenberg, E.P.3
  • 89
    • 58149392486 scopus 로고    scopus 로고
    • Simpson's paradox in a synthetic microbial system
    • Chuang, J.S., Rivoire, O. & Leibler, S. Simpson's paradox in a synthetic microbial system. Science 323, 272-275 (2009).
    • (2009) Science , vol.323 , pp. 272-275
    • Chuang, J.S.1    Rivoire, O.2    Leibler, S.3
  • 90
    • 84867200131 scopus 로고    scopus 로고
    • Engineering microbial systems to explore ecological and evolutionary dynamics
    • Tanouchi, Y., Smith, R.P. & You, L. Engineering microbial systems to explore ecological and evolutionary dynamics. Curr. Opin. Biotechnol. 23, 791-797 (2012).
    • (2012) Curr. Opin. Biotechnol. , vol.23 , pp. 791-797
    • Tanouchi, Y.1    Smith, R.P.2    You, L.3
  • 91
    • 84861439294 scopus 로고    scopus 로고
    • Density-dependent fitness benefits in quorum-sensing bacterial populations
    • Darch, S.E., West, S.A., Winzer, K. & Diggle, S.P. Density-dependent fitness benefits in quorum-sensing bacterial populations. Proc. Natl. Acad. Sci. USA 109, 8259-8263 (2012).
    • (2012) Proc. Natl. Acad. Sci. USA , vol.109 , pp. 8259-8263
    • Darch, S.E.1    West, S.A.2    Winzer, K.3    Diggle, S.P.4
  • 92
    • 84882274148 scopus 로고    scopus 로고
    • Bacterial cheating drives the population dynamics of cooperative antibiotic resistance plasmids
    • Yurtsev, E.A., Chao, H.X., Datta, M.S., Artemova, T. & Gore, J. Bacterial cheating drives the population dynamics of cooperative antibiotic resistance plasmids. Mol. Syst. Biol. 9, 300-308 (2013).
    • (2013) Mol. Syst. Biol. , vol.9 , pp. 300-308
    • Yurtsev, E.A.1    Chao, H.X.2    Datta, M.S.3    Artemova, T.4    Gore, J.5


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