Cost of antibiotic resistance and the geometry of adaptation

Molecular Biology and Evolution

Volumn 29, Issue 5, 2012, Pages 1417-1428

  Sousa, Ana ^a   Magalhaes, Sara ^b   Gordo, Isabel ^a  

^a INSTITUTO GULBENKIAN DE CIÊNCIA   (Portugal)

^b UNIVERSITY OF LISBON   (Portugal)

Author keywords

Antibiotic resistance; Compensatory adaptation; Distribution of fitness effects; Escherichia coli; Fisher's geometrical model of adaptation; Selection coefficients

Indexed keywords

ANTIBIOTIC RESISTANCE; ARTICLE; BACTERIAL GENETICS; CONTROLLED STUDY; ESCHERICHIA COLI; EVOLUTIONARY ADAPTATION; GENE FREQUENCY; GENE MUTATION; HUMAN; MATHEMATICAL MODEL; NONHUMAN; REVERTANT;

ANTI-BACTERIAL AGENTS; DRUG RESISTANCE, BACTERIAL; ESCHERICHIA COLI; EVOLUTION, MOLECULAR; GENETIC FITNESS; GENOME, BACTERIAL; MICROSATELLITE REPEATS; MODELS, GENETIC; MUTATION; PHENOTYPE; SELECTION, GENETIC; STREPTOMYCIN;

ESCHERICHIA COLI;

EID: 84862840054     PISSN: 07374038     EISSN: 15371719     Source Type: Journal    
DOI: 10.1093/molbev/msr302     Document Type: Article

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