Ribosomal mutations promote the evolution of antibiotic resistance in a multidrug environment

eLife

Volumn 6, Issue , 2017, Pages

  Gomez, James E ^a   Kaufmann Malaga, Benjamin B ^a,b,c   Wivagg, Carl N ^a,b   Kim, Peter B ^a   Silvis, Melanie R ^a   Renedo, Nikolai ^a   Ioerger, Thomas R ^d   Ahmad, Rushdy ^a   Livny, Jonathan ^a   Fishbein, Skye ^e   Sacchettini, James C ^d   Carr, Steven A ^a   Hung, Deborah T ^a,b,c  

^a BROAD INSTITUTE OF MIT AND HARVARD   (United States)

^b MASSACHUSETTS GENERAL HOSPITAL   (United States)

^c HARVARD MEDICAL SCHOOL   (United States)

^d TEXAS A AND M UNIVERSITY   (United States)

^e HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANHYDROTETRACYCLINE; CHLORAMPHENICOL; CIPROFLOXACIN; DNA TOPOISOMERASE (ATP HYDROLYSING); ERYTHROMYCIN; GENTAMICIN; ISONIAZID; KATG PROTEIN; MEROPENEM; NOVOBIOCIN; OFLOXACIN; PUROMYCIN; STREPTOMYCIN; TETRACYCLINE; BACTERIAL PROTEIN; PROTEOME;

ANTIBIOTIC RESISTANCE; ARTICLE; BACTERIAL VIABILITY; HEAT SHOCK; IC50; MINIMUM INHIBITORY CONCENTRATION; MOST PROBABLE NUMBER; MULTIDRUG RESISTANCE; MUTATION; MYCOBACTERIUM SMEGMATIS; NONHUMAN; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA SEQUENCE; SURVIVAL TIME; WESTERN BLOTTING; WHOLE GENOME SEQUENCING; BIOSYNTHESIS; DRUG EFFECTS; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENETICS; RIBOSOME;

BACTERIAL PROTEINS; DRUG RESISTANCE, BACTERIAL; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, BACTERIAL; MUTATION; MYCOBACTERIUM SMEGMATIS; PROTEOME; RIBOSOMES;

EID: 85013753478     PISSN: None     EISSN: 2050084X     Source Type: Journal    
DOI: 10.7554/eLife.20420     Document Type: Article

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