Patterns of epistasis between beneficial mutations in an antibiotic resistance gene

Molecular Biology and Evolution

Volumn 30, Issue 8, 2013, Pages 1779-1787

  Schenk, Martijn F ^a   Szendro, Ivan G ^a   Salverda, Merijn L M ^b   Krug, Joachim ^a   De Visser, J Arjan G M ^b  

^a UNIVERSITY OF COLOGNE   (Germany)

^b WAGENINGEN UNIVERSITY   (Netherlands)

Author keywords

Antibiotic resistance; Beneficial mutations; Epistasis; Fitness landscape; lactamase

Indexed keywords

ANTIINFECTIVE AGENT; BETA LACTAMASE; BETA LACTAMASE TEM 1; BETA-LACTAMASE TEM-1; CEFOTAXIME;

Β-LACTAMASE; ANTIBIOTIC RESISTANCE; ARTICLE; BENEFICIAL MUTATIONS; DRUG EFFECT; EPISTASIS; ESCHERICHIA COLI; EVOLUTION; FITNESS LANDSCAPE; GENETICS; GENOTYPE; MUTATION; PHENOTYPE; REPRODUCTIVE FITNESS; DRUG EFFECTS;

Β-LACTAMASE; ANTIBIOTIC RESISTANCE; BENEFICIAL MUTATIONS; EPISTASIS; FITNESS LANDSCAPE;

ANTI-BACTERIAL AGENTS; BETA-LACTAMASES; BIOLOGICAL EVOLUTION; CEFOTAXIME; DRUG RESISTANCE, BACTERIAL; EPISTASIS, GENETIC; ESCHERICHIA COLI; GENETIC FITNESS; GENOTYPE; MUTATION; PHENOTYPE;

EID: 84887613917     PISSN: 07374038     EISSN: 15371719     Source Type: Journal    
DOI: 10.1093/molbev/mst096     Document Type: Article

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