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Volumn 8, Issue 3, 2015, Pages 284-295

The genetic basis of the fitness costs of antimicrobial resistance: A meta-analysis approach

Author keywords

Adaptation; Antibiotic resistance; Antimicrobial resistance; Fitness cost; Microbes; Mutation; Plasmid

Indexed keywords


EID: 84925296085     PISSN: 17524563     EISSN: 17524571     Source Type: Journal    
DOI: 10.1111/eva.12202     Document Type: Article
Times cited : (281)

References (76)
  • 1
    • 79956023809 scopus 로고    scopus 로고
    • Effect of multidrug resistance-conferring mutations on the fitness and virulence of Pseudomonas aeruginosa
    • Abdelraouf, K., S. Kabbara, K. R. Ledesma, K. Poole, and V. H. Tam 2011. Effect of multidrug resistance-conferring mutations on the fitness and virulence of Pseudomonas aeruginosa. Journal of Antimicrobial Chemotherapy 66:1311-1317.
    • (2011) Journal of Antimicrobial Chemotherapy , vol.66 , pp. 1311-1317
    • Abdelraouf, K.1    Kabbara, S.2    Ledesma, K.R.3    Poole, K.4    Tam, V.H.5
  • 3
    • 33947260230 scopus 로고    scopus 로고
    • Molecular mechanisms of antibacterial multidrug resistance
    • Alekshun, M. N., and S. B. Levy 2007. Molecular mechanisms of antibacterial multidrug resistance. Cell 128:1037-1050.
    • (2007) Cell , vol.128 , pp. 1037-1050
    • Alekshun, M.N.1    Levy, S.B.2
  • 4
    • 33748693294 scopus 로고    scopus 로고
    • The biological cost of mutational antibiotic resistance: any practical conclusions?
    • Andersson, D. I. 2006. The biological cost of mutational antibiotic resistance: any practical conclusions? Current Opinion in Microbiology 9:461-465.
    • (2006) Current Opinion in Microbiology , vol.9 , pp. 461-465
    • Andersson, D.I.1
  • 5
    • 77949569493 scopus 로고    scopus 로고
    • Antibiotic resistance and its cost: is it possible to reverse resistance?
    • Andersson, D. I., and D. Hughes 2010. Antibiotic resistance and its cost: is it possible to reverse resistance? Nature Reviews Microbiology 8:260-271.
    • (2010) Nature Reviews Microbiology , vol.8 , pp. 260-271
    • Andersson, D.I.1    Hughes, D.2
  • 7
    • 0030831888 scopus 로고    scopus 로고
    • The transmission dynamics of antibiotic-resistant bacteria: the relationship between resistance in commensal organisms and antibiotic consumption
    • Austin, D. J., M. Kakehashi, and R. M. Anderson 1997. The transmission dynamics of antibiotic-resistant bacteria: the relationship between resistance in commensal organisms and antibiotic consumption. Proceedings of the Royal Society of London. Series B: Biological Sciences 264:1629-1638.
    • (1997) Proceedings of the Royal Society of London. Series B: Biological Sciences , vol.264 , pp. 1629-1638
    • Austin, D.J.1    Kakehashi, M.2    Anderson, R.M.3
  • 8
    • 0033514493 scopus 로고    scopus 로고
    • The relationship between the volume of antimicrobial consumption in human communities and the frequency of resistance
    • Austin, D. J., K. G. Kristinsson, and R. M. Anderson 1999. The relationship between the volume of antimicrobial consumption in human communities and the frequency of resistance. Proceedings of the National Academy of Sciences 96:1152-1156.
    • (1999) Proceedings of the National Academy of Sciences , vol.96 , pp. 1152-1156
    • Austin, D.J.1    Kristinsson, K.G.2    Anderson, R.M.3
  • 9
    • 84880712059 scopus 로고    scopus 로고
    • Exploring the costs of horizontal gene transfer
    • Baltrus, D. A. 2013. Exploring the costs of horizontal gene transfer. Trends in Ecology & Evolution 28:489-495.
    • (2013) Trends in Ecology & Evolution , vol.28 , pp. 489-495
    • Baltrus, D.A.1
  • 10
    • 65549165914 scopus 로고    scopus 로고
    • What antimicrobial resistance has taught us about horizontal gene transfer
    • M. Gogarten, J. Gogarten, and L. Olendzenski, eds. Humana Press, New York.
    • Barlow, M. 2009, What antimicrobial resistance has taught us about horizontal gene transfer. In M. Gogarten, J. Gogarten, and L. Olendzenski, eds. Horizontal Gene Transfer, pp. 397-411. Humana Press, New York.
    • (2009) Horizontal Gene Transfer , pp. 397-411
    • Barlow, M.1
  • 11
    • 27644586215 scopus 로고    scopus 로고
    • Fitness cost due to mutations in the 16S rRNA associated with spectinomycin resistance in Chlamydia psittaci 6BC
    • Binet, R., and A. T. Maurelli 2005. Fitness cost due to mutations in the 16S rRNA associated with spectinomycin resistance in Chlamydia psittaci 6BC. Antimicrobial Agents and Chemotheraphy 49:4455-4464.
    • (2005) Antimicrobial Agents and Chemotheraphy , vol.49 , pp. 4455-4464
    • Binet, R.1    Maurelli, A.T.2
  • 12
    • 33747625237 scopus 로고    scopus 로고
    • Mechanisms of multidrug resistance in Acenitobacter species and Pseudomonas aeruginosa
    • Bonomo, R. A., and D. Szabo 2006. Mechanisms of multidrug resistance in Acenitobacter species and Pseudomonas aeruginosa. Clinical Infectious Disease 43:S49-S56.
    • (2006) Clinical Infectious Disease , vol.43 , pp. S49-S56
    • Bonomo, R.A.1    Szabo, D.2
  • 13
    • 0023694037 scopus 로고
    • Evolution of a bacteria/plasmid association
    • Bouma, J. E., and R. E. Lenski 1988. Evolution of a bacteria/plasmid association. Nature 335:351-352.
    • (1988) Nature , vol.335 , pp. 351-352
    • Bouma, J.E.1    Lenski, R.E.2
  • 14
    • 84874027222 scopus 로고    scopus 로고
    • Quantitative contributions of targeration and decreased drug accumulation to Pseudomonas aeruginosa fluoroquinolone resistance
    • Bruchmann, S., A. Dötsch, B. Nouri, I. F. Chaberny, and S. Häussler 2013. Quantitative contributions of target alteration and decreased drug accumulation to Pseudomonas aeruginosa fluoroquinolone resistance. Antimicrobial Agents and Chemotherapy 57:1361-1368.
    • (2013) Antimicrobial Agents and Chemotherapy , vol.57 , pp. 1361-1368
    • Bruchmann, S.1    Dötsch, A.2    Nouri, B.3    Chaberny, I.F.4    Häussler, S.5
  • 15
    • 70350457941 scopus 로고    scopus 로고
    • The glycerol-3-phosphate permease glpt is the only fosfomycin transporter in Pseudomonas aeruginosa
    • Castaneda-Garcia, A., A. Rodriguez-Rojas, J. R. Guelfo, and J. Blazquez 2009. The glycerol-3-phosphate permease glpt is the only fosfomycin transporter in Pseudomonas aeruginosa. Journal of Bacteriology 191:6968-6974.
    • (2009) Journal of Bacteriology , vol.191 , pp. 6968-6974
    • Castaneda-Garcia, A.1    Rodriguez-Rojas, A.2    Guelfo, J.R.3    Blazquez, J.4
  • 16
    • 77956569701 scopus 로고    scopus 로고
    • Metallo-beta-lactamase expression confers an advantage to Pseudomonas aeruginosa isolates compared with other beta-lactam resistance mechanisms, favoring the prevalence of metallo-beta-lactamase producers in a clinical environment
    • Corich, L., L. Dolzani, E. A. Tonin, L. A. Vitali, and C. Lagatolla 2010. Metallo-beta-lactamase expression confers an advantage to Pseudomonas aeruginosa isolates compared with other beta-lactam resistance mechanisms, favoring the prevalence of metallo-beta-lactamase producers in a clinical environment. Microbial Drug Resistance 16:223-230.
    • (2010) Microbial Drug Resistance , vol.16 , pp. 223-230
    • Corich, L.1    Dolzani, L.2    Tonin, E.A.3    Vitali, L.A.4    Lagatolla, C.5
  • 17
    • 0347992016 scopus 로고    scopus 로고
    • Amelioration of the cost of conjugative plasmid carriage in Eschericha coli K12
    • Dahlberg, C., and L. Chao 2003. Amelioration of the cost of conjugative plasmid carriage in Eschericha coli K12. Genetics 165:1641-1649.
    • (2003) Genetics , vol.165 , pp. 1641-1649
    • Dahlberg, C.1    Chao, L.2
  • 18
    • 25444496227 scopus 로고    scopus 로고
    • The evolution of a conjugative plasmid and its ability to increase bacterial fitness
    • Dionisio, F., I. C. Conceição, A. C. R. Marques, L. Fernandes, and I. Gordo 2005. The evolution of a conjugative plasmid and its ability to increase bacterial fitness. Biology Letters 1:250-252.
    • (2005) Biology Letters , vol.1 , pp. 250-252
    • Dionisio, F.1    Conceição, I.C.2    Marques, A.C.R.3    Fernandes, L.4    Gordo, I.5
  • 19
    • 24644435909 scopus 로고    scopus 로고
    • Assessment of the fitness impacts on Escherichia coli of acquisition of antibiotic resistance genes encoded by different types of genetic element
    • Enne, V. I., A. A. Delsol, G. R. Davis, S. L. Hayward, J. M. Roe, and P. M. Bennett 2005. Assessment of the fitness impacts on Escherichia coli of acquisition of antibiotic resistance genes encoded by different types of genetic element. Journal of Antimicrobial Chemotherapy 56:544-551.
    • (2005) Journal of Antimicrobial Chemotherapy , vol.56 , pp. 544-551
    • Enne, V.I.1    Delsol, A.A.2    Davis, G.R.3    Hayward, S.L.4    Roe, J.M.5    Bennett, P.M.6
  • 20
    • 84884992001 scopus 로고    scopus 로고
    • Genomic analysis identifies targets of convergent positive selection in drug-resistant Mycobacterium tuberculosis
    • Farhat, M. R., B. J. Shapiro, K. J. Kieser, R. Sultana, K. R. Jacobson, T. C. Victor, R. M. Warren et al. 2013. Genomic analysis identifies targets of convergent positive selection in drug-resistant Mycobacterium tuberculosis. Nature Genetics 45:1183-1189.
    • (2013) Nature Genetics , vol.45 , pp. 1183-1189
    • Farhat, M.R.1    Shapiro, B.J.2    Kieser, K.J.3    Sultana, R.4    Jacobson, K.R.5    Victor, T.C.6    Warren, R.M.7
  • 21
    • 67049086956 scopus 로고    scopus 로고
    • Fitness cost of vana-type vancomycin resistance in methicillin-resistant Staphylococcus aureus
    • Foucault, M.-L., P. Courvalin, and C. Grillot-Courvalin 2009. Fitness cost of vana-type vancomycin resistance in methicillin-resistant Staphylococcus aureus. Antimicrobial Agents and Chemotheraphy 53:2354-2359.
    • (2009) Antimicrobial Agents and Chemotheraphy , vol.53 , pp. 2354-2359
    • Foucault, M.-L.1    Courvalin, P.2    Grillot-Courvalin, C.3
  • 23
    • 33947537711 scopus 로고    scopus 로고
    • Comparison of outpatient systemic antibacterial use in 2004 in the United States and 27 European countries
    • Goossens, H., M. Ferech, S. Coenen, and P. Stephens, Group E.S.o.A.C.P. 2007, Comparison of outpatient systemic antibacterial use in 2004 in the United States and 27 European countries. Clinical Infectious Diseases 44, 1091-1095.
    • (2007) Clinical Infectious Diseases , vol.44 , pp. 1091-1095
    • Goossens, H.1    Ferech, M.2    Coenen, S.3    Stephens, P.4
  • 25
    • 0033040602 scopus 로고    scopus 로고
    • Statistical issues in ecological meta-analyses
    • Gurevitch, J., and L. V. Hedges 1999. Statistical issues in ecological meta-analyses. Ecology 80:1142-1149.
    • (1999) Ecology , vol.80 , pp. 1142-1149
    • Gurevitch, J.1    Hedges, L.V.2
  • 27
    • 0041527013 scopus 로고    scopus 로고
    • Fitness of antibiotic resistant Staphylococcus epidermidis assessed by competition on the skin of human volunteers
    • Gustafsson, I., O. Cars, and D. I. Andersson 2003. Fitness of antibiotic resistant Staphylococcus epidermidis assessed by competition on the skin of human volunteers. Journal of Antimicrobial Chemotherapy 52:258-263.
    • (2003) Journal of Antimicrobial Chemotherapy , vol.52 , pp. 258-263
    • Gustafsson, I.1    Cars, O.2    Andersson, D.I.3
  • 28
    • 79960836520 scopus 로고    scopus 로고
    • epistasis buffers the fitness effects of rifampicin- resistance mutations in Pseudomonas aeruginosa
    • Hall, A. R., and R. C. MacLean 2011. epistasis buffers the fitness effects of rifampicin- resistance mutations in Pseudomonas aeruginosa. Evolution 65:2370-2379.
    • (2011) Evolution , vol.65 , pp. 2370-2379
    • Hall, A.R.1    MacLean, R.C.2
  • 29
    • 0033037138 scopus 로고    scopus 로고
    • The meta-analysis of response ratios in experimental ecology
    • Hedges, L. V., J. Gurevitch, and P. S. Curtis 1999. The meta-analysis of response ratios in experimental ecology. Ecology 80:1150-1156.
    • (1999) Ecology , vol.80 , pp. 1150-1156
    • Hedges, L.V.1    Gurevitch, J.2    Curtis, P.S.3
  • 30
    • 0020645470 scopus 로고
    • Conjugative plasmids in bacteria of the /'pre-antibiotic/' era
    • Hughes, V. M., and N. Datta 1983. Conjugative plasmids in bacteria of the /'pre-antibiotic/' era. Nature 302:725-726.
    • (1983) Nature , vol.302 , pp. 725-726
    • Hughes, V.M.1    Datta, N.2
  • 31
    • 0033999155 scopus 로고    scopus 로고
    • Molecular mechanisms of fluoroquinolone resistance in Pseudomonas aeruginosa isolates from cystic fibrosis patients
    • Jalal, S., O. Ciofu, N. Høiby, N. Gotoh, and B. Wretlind 2000. Molecular mechanisms of fluoroquinolone resistance in Pseudomonas aeruginosa isolates from cystic fibrosis patients. Antimicrobial Agents and Chemotheraphy 44:710-712.
    • (2000) Antimicrobial Agents and Chemotheraphy , vol.44 , pp. 710-712
    • Jalal, S.1    Ciofu, O.2    Høiby, N.3    Gotoh, N.4    Wretlind, B.5
  • 32
    • 84881238984 scopus 로고    scopus 로고
    • Large mobile genetic elements carrying resistance genes that do not confer a fitness burden in healthcare-associated meticillin-resistant Staphylococcus aureus
    • Knight, G. M., E. L. Budd, and J. A. Lindsay 2013. Large mobile genetic elements carrying resistance genes that do not confer a fitness burden in healthcare-associated meticillin-resistant Staphylococcus aureus. Microbiology 159:1661-1672.
    • (2013) Microbiology , vol.159 , pp. 1661-1672
    • Knight, G.M.1    Budd, E.L.2    Lindsay, J.A.3
  • 33
    • 84861553437 scopus 로고    scopus 로고
    • Impact of fluoroquinolone resistance mutations on gonococcal fitness and in vivo selection for compensatory mutations
    • Kunz, A. N., A. A. Begum, H. Wu, J. A. D'Ambrozio, J. M. Robinson, W. M. Shafer, M. C. Bash et al. 2012. Impact of fluoroquinolone resistance mutations on gonococcal fitness and in vivo selection for compensatory mutations. Journal of Infectious Diseases, 205:1821-1829.
    • (2012) Journal of Infectious Diseases , vol.205 , pp. 1821-1829
    • Kunz, A.N.1    Begum, A.A.2    Wu, H.3    D'Ambrozio, J.A.4    Robinson, J.M.5    Shafer, W.M.6    Bash, M.C.7
  • 34
    • 33846623697 scopus 로고    scopus 로고
    • Lysostaphin-resistant variants of staphylococcus aureus demonstrate reduced fitness in vitro and in vivo
    • Kusuma, C., A. Jadanova, T. Chanturiya, and J. F. Kokai-Kun 2007. Lysostaphin-resistant variants of staphylococcus aureus demonstrate reduced fitness in vitro and in vivo. Antimicrobial Agents and Chemotheraphy 51:475-482.
    • (2007) Antimicrobial Agents and Chemotheraphy , vol.51 , pp. 475-482
    • Kusuma, C.1    Jadanova, A.2    Chanturiya, T.3    Kokai-Kun, J.F.4
  • 35
    • 10944272743 scopus 로고    scopus 로고
    • Antibacterial resistance worldwide: causes, challenges and responses
    • Levy, S. B., and B. Marshall 2004. Antibacterial resistance worldwide: causes, challenges and responses. Nature Medicine, 10:S122-S129.
    • (2004) Nature Medicine , vol.10 , pp. S122-S129
    • Levy, S.B.1    Marshall, B.2
  • 36
    • 19544393748 scopus 로고    scopus 로고
    • Biological cost of single and multiple norfloxacin resistance mutations in Escherichia coli implicated in urinary tract infections
    • Lindgren, P. K., L. L. Marcusson, D. Sandvang, N. Frimodt-Møller, and D. Hughes 2005. Biological cost of single and multiple norfloxacin resistance mutations in Escherichia coli implicated in urinary tract infections. Antimicrobial Agents and Chemotheraphy 49:2343-2351.
    • (2005) Antimicrobial Agents and Chemotheraphy , vol.49 , pp. 2343-2351
    • Lindgren, P.K.1    Marcusson, L.L.2    Sandvang, D.3    Frimodt-Møller, N.4    Hughes, D.5
  • 38
    • 70449124604 scopus 로고    scopus 로고
    • Antibacterial-resistant Pseudomonas aeruginosa: clinical impact and complex regulation of chromosomally encoded resistance mechanisms
    • Lister, P. D., D. J. Wolter, and N. D. Hanson 2009. Antibacterial-resistant Pseudomonas aeruginosa: clinical impact and complex regulation of chromosomally encoded resistance mechanisms. Clinical Microbiology Reviews 22:582-610.
    • (2009) Clinical Microbiology Reviews , vol.22 , pp. 582-610
    • Lister, P.D.1    Wolter, D.J.2    Hanson, N.D.3
  • 39
    • 0036498656 scopus 로고    scopus 로고
    • Multiple mechanisms of antimicrobial resistance in Pseudomonas aeruginosa: our worst nightmare?
    • Livermore, D. M. 2002. Multiple mechanisms of antimicrobial resistance in Pseudomonas aeruginosa: our worst nightmare? Clinical Infectious Diseases 34:634-640.
    • (2002) Clinical Infectious Diseases , vol.34 , pp. 634-640
    • Livermore, D.M.1
  • 40
    • 77952556349 scopus 로고    scopus 로고
    • The population genetics of antibiotic resistance: integrating molecular mechanisms and treatment contexts
    • MacLean, R. C., A. R. Hall, G. G. Perron, and A. Buckling 2010. The population genetics of antibiotic resistance: integrating molecular mechanisms and treatment contexts. Nature Reviews Genetics 11:405-414.
    • (2010) Nature Reviews Genetics , vol.11 , pp. 405-414
    • MacLean, R.C.1    Hall, A.R.2    Perron, G.G.3    Buckling, A.4
  • 42
    • 34548407803 scopus 로고    scopus 로고
    • A fitness cost associated with the antibiotic resistance enzyme SME-1 beta-lactamase
    • Marciano, D. C., O. Y. Karkouti, and T. Palzkill 2007. A fitness cost associated with the antibiotic resistance enzyme SME-1 beta-lactamase. Genetics 176:2381-2392.
    • (2007) Genetics , vol.176 , pp. 2381-2392
    • Marciano, D.C.1    Karkouti, O.Y.2    Palzkill, T.3
  • 43
    • 70049100936 scopus 로고    scopus 로고
    • Interplay in the selection of fluoroquinolone resistance and bacterial fitness
    • Marcusson, L. L., N. Frimodt-Møller, and D. Hughes 2009. Interplay in the selection of fluoroquinolone resistance and bacterial fitness. PLoS Pathogens 5:e1000541.
    • (2009) PLoS Pathogens , vol.5
    • Marcusson, L.L.1    Frimodt-Møller, N.2    Hughes, D.3
  • 45
    • 84860182466 scopus 로고    scopus 로고
    • The evolution of conflict resolution between plasmids and their bacterial hosts
    • Mc Ginty, S. É., and D. J. Rankin 2012. The evolution of conflict resolution between plasmids and their bacterial hosts. Evolution 66:1662-1670.
    • (2012) Evolution , vol.66 , pp. 1662-1670
    • Mc Ginty, S.E.1    Rankin, D.J.2
  • 46
    • 78650931883 scopus 로고    scopus 로고
    • Horizontal gene transfer and the evolution of bacterial cooperation
    • Mc Ginty, S. E., D. J. Rankin, and S. P. Brown 2011. Horizontal gene transfer and the evolution of bacterial cooperation. Evolution 65:21-32.
    • (2011) Evolution , vol.65 , pp. 21-32
    • Mc Ginty, S.E.1    Rankin, D.J.2    Brown, S.P.3
  • 47
    • 54049144292 scopus 로고    scopus 로고
    • Benefit of having multiple ampd genes for acquiring β-lactam resistance without losing fitness and virulence in pseudomonas aeruginosa
    • Moya, B., C. Juan, S. Albertí, J. L. Pérez, and A. Oliver 2008. Benefit of having multiple ampd genes for acquiring β-lactam resistance without losing fitness and virulence in pseudomonas aeruginosa. Antimicrobial Agents and Chemotheraphy 52:3694-3700.
    • (2008) Antimicrobial Agents and Chemotheraphy , vol.52 , pp. 3694-3700
    • Moya, B.1    Juan, C.2    Albertí, S.3    Pérez, J.L.4    Oliver, A.5
  • 48
    • 84875264261 scopus 로고    scopus 로고
    • The heterogeneous evolution of multidrug-resistant Mycobacterium tuberculosis
    • Muller, B., S. Borrell, G. Rose, and S. Gagneux 2013. The heterogeneous evolution of multidrug-resistant Mycobacterium tuberculosis. Trends in Genetics 29:160-169.
    • (2013) Trends in Genetics , vol.29 , pp. 160-169
    • Muller, B.1    Borrell, S.2    Rose, G.3    Gagneux, S.4
  • 49
    • 70350488795 scopus 로고    scopus 로고
    • Horizontal gene transfer of the secretome drives the evolution of bacterial cooperation and virulence
    • Nogueira, T., D. J. Rankin, M. Touchon, F. Taddei, S. P. Brown, and E. P. C. Rocha 2009. Horizontal gene transfer of the secretome drives the evolution of bacterial cooperation and virulence. Current Biology 19:1683-1691.
    • (2009) Current Biology , vol.19 , pp. 1683-1691
    • Nogueira, T.1    Rankin, D.J.2    Touchon, M.3    Taddei, F.4    Brown, S.P.5    Rocha, E.P.C.6
  • 50
    • 36749058900 scopus 로고    scopus 로고
    • Genetic and phenotypic identification of fusidic acid-resistant mutants with the small-colony-variant phenotype in Staphylococcus aureus
    • Norström, T., J. Lannergård, and D. Hughes 2007. Genetic and phenotypic identification of fusidic acid-resistant mutants with the small-colony-variant phenotype in Staphylococcus aureus. Antimicrobial Agents and Chemotheraphy 51:4438-4446.
    • (2007) Antimicrobial Agents and Chemotheraphy , vol.51 , pp. 4438-4446
    • Norström, T.1    Lannergård, J.2    Hughes, D.3
  • 51
    • 84864386394 scopus 로고    scopus 로고
    • Overproduction of the multidrug efflux pump MexEF-OprN does not impair Pseudomonas aeruginosa fitness in competition tests, but produces specific changes in bacterial regulatory networks
    • Olivares, J., C. Alvarez-Ortega, J. F. Linares, F. Rojo, T. Köhler, and J. L. Martínez 2012. Overproduction of the multidrug efflux pump MexEF-OprN does not impair Pseudomonas aeruginosa fitness in competition tests, but produces specific changes in bacterial regulatory networks. Environmental Microbiology 14:1968-1981.
    • (2012) Environmental Microbiology , vol.14 , pp. 1968-1981
    • Olivares, J.1    Alvarez-Ortega, C.2    Linares, J.F.3    Rojo, F.4    Köhler, T.5    Martínez, J.L.6
  • 52
    • 33846584956 scopus 로고    scopus 로고
    • Caenorhabditis elegans as a model to determine fitness of antibiotic-resistant Salmonella enterica serovar typhimurium
    • Paulander, W., A. Pennhag, D. I. Andersson, and S. Maisnier-Patin 2007. Caenorhabditis elegans as a model to determine fitness of antibiotic-resistant Salmonella enterica serovar typhimurium. Antimicrobial Agents and Chemotheraphy 51:766-769.
    • (2007) Antimicrobial Agents and Chemotheraphy , vol.51 , pp. 766-769
    • Paulander, W.1    Pennhag, A.2    Andersson, D.I.3    Maisnier-Patin, S.4
  • 53
    • 70649114603 scopus 로고    scopus 로고
    • The fitness cost of streptomycin resistance depends on rpsl mutation, carbon source and RpoS (σS)
    • Paulander, W., S. Maisnier-Patin, and D. I. Andersson 2009. The fitness cost of streptomycin resistance depends on rpsl mutation, carbon source and RpoS (σS). Genetics 183:539-546.
    • (2009) Genetics , vol.183 , pp. 539-546
    • Paulander, W.1    Maisnier-Patin, S.2    Andersson, D.I.3
  • 54
    • 78651088019 scopus 로고    scopus 로고
    • Escape from growth restriction in small colony variants of Salmonella typhimurium by gene amplification and mutation
    • Pränting, M., and D. I. Andersson 2011. Escape from growth restriction in small colony variants of Salmonella typhimurium by gene amplification and mutation. Molecular Microbiology 79:305-315.
    • (2011) Molecular Microbiology , vol.79 , pp. 305-315
    • Pränting, M.1    Andersson, D.I.2
  • 55
    • 48749128095 scopus 로고    scopus 로고
    • Mechanism and fitness costs of PR-39 resistance in Salmonella enterica serovar typhimurium LT2
    • Pränting, M., A. Negrea, M. Rhen, and D. I. Andersson 2008. Mechanism and fitness costs of PR-39 resistance in Salmonella enterica serovar typhimurium LT2. Antimicrobial Agents and Chemotheraphy 52:2734-2741.
    • (2008) Antimicrobial Agents and Chemotheraphy , vol.52 , pp. 2734-2741
    • Pränting, M.1    Negrea, A.2    Rhen, M.3    Andersson, D.I.4
  • 56
    • 78650305634 scopus 로고    scopus 로고
    • What traits are carried on mobile genetic elements, and why[quest]
    • Rankin, D. J., E. P. C. Rocha, and S. P. Brown 2011. What traits are carried on mobile genetic elements, and why[quest]. Heredity 106:1-10.
    • (2011) Heredity , vol.106 , pp. 1-10
    • Rankin, D.J.1    Rocha, E.P.C.2    Brown, S.P.3
  • 59
    • 84859170554 scopus 로고    scopus 로고
    • Transfer of an Escherichia coli ST131 multiresistance cassette has created a Klebsiella pneumoniae-specific plasmid associated with a major nosocomial outbreak
    • Sandegren, L., M. Linkevicius, B. Lytsy, A. Melhus, and D. I. Andersson 2012. Transfer of an Escherichia coli ST131 multiresistance cassette has created a Klebsiella pneumoniae-specific plasmid associated with a major nosocomial outbreak. Journal of Antimicrobial Chemotherapy 67:74-83.
    • (2012) Journal of Antimicrobial Chemotherapy , vol.67 , pp. 74-83
    • Sandegren, L.1    Linkevicius, M.2    Lytsy, B.3    Melhus, A.4    Andersson, D.I.5
  • 61
    • 0029921764 scopus 로고    scopus 로고
    • Reducing antibiotic resistance
    • Schrag, S. J., and V. Perrot 1996. Reducing antibiotic resistance. Nature 381:120-121.
    • (1996) Nature , vol.381 , pp. 120-121
    • Schrag, S.J.1    Perrot, V.2
  • 62
    • 33845904111 scopus 로고    scopus 로고
    • Small-colony variants: a novel mechanism for triclosan resistance in methicillin-resistant Staphylococcus aureus
    • Seaman, P. F., D. Ochs, and M. J. Day 2007. Small-colony variants: a novel mechanism for triclosan resistance in methicillin-resistant Staphylococcus aureus. Journal of Antimicrobial Chemotherapy 59:43-50.
    • (2007) Journal of Antimicrobial Chemotherapy , vol.59 , pp. 43-50
    • Seaman, P.F.1    Ochs, D.2    Day, M.J.3
  • 63
    • 0035721741 scopus 로고    scopus 로고
    • The molecular basis of resistance to isoniazid, rifampin, and pyrazinamide in Mycobacterium tuberculosis
    • Somoskovi, A., L. Parsons, and M. Salfinger 2001. The molecular basis of resistance to isoniazid, rifampin, and pyrazinamide in Mycobacterium tuberculosis. Respiratory Research 2:164-168.
    • (2001) Respiratory Research , vol.2 , pp. 164-168
    • Somoskovi, A.1    Parsons, L.2    Salfinger, M.3
  • 68
    • 0035038579 scopus 로고    scopus 로고
    • Genetic characterization of highly fluoroquinolone-resistant clinical Escherichia coli strains from China: role ofacrR mutations
    • Wang, H., J. L. Dzink-Fox, M. Chen, and S. B. Levy 2001. Genetic characterization of highly fluoroquinolone-resistant clinical Escherichia coli strains from China: role ofacrR mutations. Antimicrobial Agents and Chemotheraphy 45:1515-1521.
    • (2001) Antimicrobial Agents and Chemotheraphy , vol.45 , pp. 1515-1521
    • Wang, H.1    Dzink-Fox, J.L.2    Chen, M.3    Levy, S.B.4
  • 69
    • 65249103440 scopus 로고    scopus 로고
    • The cost of multiple drug resistance in Pseudomonas aeruginosa
    • Ward, H., G. G. Perron, and R. C. Maclean 2009. The cost of multiple drug resistance in Pseudomonas aeruginosa. Journal of Evolutionary Biology 22:997-1003.
    • (2009) Journal of Evolutionary Biology , vol.22 , pp. 997-1003
    • Ward, H.1    Perron, G.G.2    Maclean, R.C.3
  • 70
    • 0020791848 scopus 로고
    • Rifampin: mechanisms of action and resistance
    • Wehrli, W. 1983. Rifampin: mechanisms of action and resistance. Reviews of Infectious Diseases 5:S407-S411.
    • (1983) Reviews of Infectious Diseases , vol.5 , pp. S407-S411
    • Wehrli, W.1
  • 71
    • 0035183855 scopus 로고    scopus 로고
    • Genetic analyses of mutations contributing to fluoroquinolone resistance in clinical isolates of Streptococcus pneumoniae
    • Weigel, L. M., G. J. Anderson, R. R. Facklam, and F. C. Tenover 2001. Genetic analyses of mutations contributing to fluoroquinolone resistance in clinical isolates of Streptococcus pneumoniae. Antimicrobial Agents and Chemotheraphy 45:3517-3523.
    • (2001) Antimicrobial Agents and Chemotheraphy , vol.45 , pp. 3517-3523
    • Weigel, L.M.1    Anderson, G.J.2    Facklam, R.R.3    Tenover, F.C.4
  • 72
    • 33645666942 scopus 로고    scopus 로고
    • Darwinian evolution can follow only very few mutational paths to fitter proteins
    • Weinreich, D. M., N. F. Delaney, M. A. DePristo, and D. L. Hartl 2006. Darwinian evolution can follow only very few mutational paths to fitter proteins. Science 312:111-114.
    • (2006) Science , vol.312 , pp. 111-114
    • Weinreich, D.M.1    Delaney, N.F.2    DePristo, M.A.3    Hartl, D.L.4
  • 74
    • 84885009252 scopus 로고    scopus 로고
    • Genome sequencing of 161 Mycobacterium tuberculosis isolates from China identifies genes and intergenic regions associated with drug resistance
    • Zhang, H., D. Li, L. Zhao, J. Fleming, N. Lin, T. Wang, Z. Liu et al. 2013. Genome sequencing of 161 Mycobacterium tuberculosis isolates from China identifies genes and intergenic regions associated with drug resistance. Nature Genetics 45:1255-1260.
    • (2013) Nature Genetics , vol.45 , pp. 1255-1260
    • Zhang, H.1    Li, D.2    Zhao, L.3    Fleming, J.4    Lin, N.5    Wang, T.6    Liu, Z.7
  • 75
    • 77349090260 scopus 로고    scopus 로고
    • Error-prone initiation factor 2 mutations reduce the fitness cost of antibiotic resistance
    • Zorzet, A., M. Y. Pavlov, A. I. Nilsson, M. Ehrenberg, and D. I. Andersson 2010. Error-prone initiation factor 2 mutations reduce the fitness cost of antibiotic resistance. Molecular Microbiology 75:1299-1313.
    • (2010) Molecular Microbiology , vol.75 , pp. 1299-1313
    • Zorzet, A.1    Pavlov, M.Y.2    Nilsson, A.I.3    Ehrenberg, M.4    Andersson, D.I.5
  • 76
    • 84864520020 scopus 로고    scopus 로고
    • Compensatory mutations in agrC partly restore fitness in vitro to peptide deformylase inhibitor-resistant Staphylococcus aureus
    • Zorzet, A., J. M. Andersen, A. I. Nilsson, N. F. Møller, and D. I. Andersson 2012. Compensatory mutations in agrC partly restore fitness in vitro to peptide deformylase inhibitor-resistant Staphylococcus aureus. Journal of Antimicrobial Chemotherapy 67:1835-1842.
    • (2012) Journal of Antimicrobial Chemotherapy , vol.67 , pp. 1835-1842
    • Zorzet, A.1    Andersen, J.M.2    Nilsson, A.I.3    Møller, N.F.4    Andersson, D.I.5


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