메뉴 건너뛰기




Volumn 13, Issue 2, 2018, Pages 383-388

Editing the Genome Without Double-Stranded DNA Breaks

Author keywords

[No Author keywords available]

Indexed keywords

MESSENGER RNA; OLIGONUCLEOTIDE; TRANSCRIPTOME; CRISPR ASSOCIATED PROTEIN; CYTIDINE DEAMINASE; DNA; ENDONUCLEASE; GUIDE RNA; URACIL DNA GLYCOSIDASE;

EID: 85042225660     PISSN: 15548929     EISSN: 15548937     Source Type: Journal    
DOI: 10.1021/acschembio.7b00710     Document Type: Review
Times cited : (84)

References (79)
  • 1
    • 0029899891 scopus 로고    scopus 로고
    • Genetic manipulation of genomes with rare-cutting endonucleases
    • Jasin, M. (1996) Genetic manipulation of genomes with rare-cutting endonucleases Trends Genet. 12, 224-228 10.1016/0168-9525(96)10019-6
    • (1996) Trends Genet. , vol.12 , pp. 224-228
    • Jasin, M.1
  • 2
    • 54849404458 scopus 로고    scopus 로고
    • MMEJ repair of double-strand breaks (director's cut): Deleted sequences and alternative endings
    • McVey, M. and Lee, S. E. (2008) MMEJ repair of double-strand breaks (director's cut): deleted sequences and alternative endings Trends Genet. 24, 529-538 10.1016/j.tig.2008.08.007
    • (2008) Trends Genet. , vol.24 , pp. 529-538
    • McVey, M.1    Lee, S.E.2
  • 3
    • 0031607707 scopus 로고    scopus 로고
    • 5 DNA Breakage and Repair
    • Jeggo, P. A. (1998) 5 DNA Breakage and Repair Adv. Genet. 38, 185-218 10.1016/S0065-2660(08)60144-3
    • (1998) Adv. Genet. , vol.38 , pp. 185-218
    • Jeggo, P.A.1
  • 4
    • 0026583875 scopus 로고
    • Two alternative pathways of double-strand break repair that are kinetically separable and independently modulated
    • Fishman-Lobell, J., Rudin, N., and Haber, J. E. (1992) Two alternative pathways of double-strand break repair that are kinetically separable and independently modulated Mol. Cell. Biol. 12, 1292-1303 10.1128/MCB.12.3.1292
    • (1992) Mol. Cell. Biol. , vol.12 , pp. 1292-1303
    • Fishman-Lobell, J.1    Rudin, N.2    Haber, J.E.3
  • 5
    • 0023813873 scopus 로고
    • Efficient repair of HO-induced chromosomal breaks in Saccharomyces cerevisiae by recombination between flanking homologous sequences
    • Rudin, N. and Haber, J. E. (1988) Efficient repair of HO-induced chromosomal breaks in Saccharomyces cerevisiae by recombination between flanking homologous sequences Mol. Cell. Biol. 8, 3918-3928 10.1128/MCB.8.9.3918
    • (1988) Mol. Cell. Biol. , vol.8 , pp. 3918-3928
    • Rudin, N.1    Haber, J.E.2
  • 6
    • 85019742802 scopus 로고    scopus 로고
    • CRISPR-Cas9 Structures and Mechanisms
    • Jiang, F. and Doudna, J. A. (2017) CRISPR-Cas9 Structures and Mechanisms Annu. Rev. Biophys. 46, 505-529 10.1146/annurev-biophys-062215-010822
    • (2017) Annu. Rev. Biophys. , vol.46 , pp. 505-529
    • Jiang, F.1    Doudna, J.A.2
  • 8
    • 84865070369 scopus 로고    scopus 로고
    • A Programmable Dual-RNA-Guided DNA Endonuclease in Adaptive Bacterial Immunity
    • Jinek, M., Chylinski, K., Fonfara, I., Hauer, M., Doudna, J. A., and Charpentier, E. (2012) A Programmable Dual-RNA-Guided DNA Endonuclease in Adaptive Bacterial Immunity Science 337, 816-821 10.1126/science.1225829
    • (2012) Science , vol.337 , pp. 816-821
    • Jinek, M.1    Chylinski, K.2    Fonfara, I.3    Hauer, M.4    Doudna, J.A.5    Charpentier, E.6
  • 9
    • 84876567971 scopus 로고    scopus 로고
    • RNA-programmed genome editing in human cells
    • Jinek, M., East, A., Cheng, A., Lin, S., Ma, E., and Doudna, J. (2013) RNA-programmed genome editing in human cells eLife 2, e00471 10.7554/eLife.00471
    • (2013) ELife , vol.2 , pp. e00471
    • Jinek, M.1    East, A.2    Cheng, A.3    Lin, S.4    Ma, E.5    Doudna, J.6
  • 12
    • 85006705751 scopus 로고    scopus 로고
    • CRISPR-Based Technologies for the Manipulation of Eukaryotic Genomes
    • Komor, A. C., Badran, A. H., and Liu, D. R. (2017) CRISPR-Based Technologies for the Manipulation of Eukaryotic Genomes Cell 168, 20-36 10.1016/j.cell.2016.10.044
    • (2017) Cell , vol.168 , pp. 20-36
    • Komor, A.C.1    Badran, A.H.2    Liu, D.R.3
  • 13
    • 85010953630 scopus 로고    scopus 로고
    • Precise and efficient scarless genome editing in stem cells using CORRECT
    • Kwart, D., Paquet, D., Teo, S., and Tessier-Lavigne, M. (2017) Precise and efficient scarless genome editing in stem cells using CORRECT Nat. Protoc. 12, 329-354 10.1038/nprot.2016.171
    • (2017) Nat. Protoc. , vol.12 , pp. 329-354
    • Kwart, D.1    Paquet, D.2    Teo, S.3    Tessier-Lavigne, M.4
  • 14
    • 84929166074 scopus 로고    scopus 로고
    • Increasing the efficiency of precise genome editing with CRISPR-Cas9 by inhibition of nonhomologous end joining
    • Maruyama, T., Dougan, S. K., Truttmann, M. C., Bilate, A. M., Ingram, J. R., and Ploegh, H. L. (2015) Increasing the efficiency of precise genome editing with CRISPR-Cas9 by inhibition of nonhomologous end joining Nat. Biotechnol. 33, 538-542 10.1038/nbt.3190
    • (2015) Nat. Biotechnol. , vol.33 , pp. 538-542
    • Maruyama, T.1    Dougan, S.K.2    Truttmann, M.C.3    Bilate, A.M.4    Ingram, J.R.5    Ploegh, H.L.6
  • 15
    • 84929147435 scopus 로고    scopus 로고
    • Increasing the efficiency of homology-directed repair for CRISPR-Cas9-induced precise gene editing in mammalian cells
    • Chu, V. T., Weber, T., Wefers, B., Wurst, W., Sander, S., Rajewsky, K., and Kuhn, R. (2015) Increasing the efficiency of homology-directed repair for CRISPR-Cas9-induced precise gene editing in mammalian cells Nat. Biotechnol. 33, 543-548 10.1038/nbt.3198
    • (2015) Nat. Biotechnol. , vol.33 , pp. 543-548
    • Chu, V.T.1    Weber, T.2    Wefers, B.3    Wurst, W.4    Sander, S.5    Rajewsky, K.6    Kuhn, R.7
  • 16
    • 84983792922 scopus 로고    scopus 로고
    • Enhanced homology-directed human genome engineering by controlled timing of CRISPR/Cas9 delivery
    • Lin, S., Staahl, B. T., Alla, R. K., and Doudna, J. A. (2014) Enhanced homology-directed human genome engineering by controlled timing of CRISPR/Cas9 delivery eLife 3, e04766 10.7554/eLife.04766
    • (2014) ELife , vol.3 , pp. e04766
    • Lin, S.1    Staahl, B.T.2    Alla, R.K.3    Doudna, J.A.4
  • 17
    • 84960911917 scopus 로고    scopus 로고
    • Enhancing homology-directed genome editing by catalytically active and inactive CRISPR-Cas9 using asymmetric donor DNA
    • Richardson, C. D., Ray, G. J., DeWitt, M. A., Curie, G. L., and Corn, J. E. (2016) Enhancing homology-directed genome editing by catalytically active and inactive CRISPR-Cas9 using asymmetric donor DNA Nat. Biotechnol. 34, 339-344 10.1038/nbt.3481
    • (2016) Nat. Biotechnol. , vol.34 , pp. 339-344
    • Richardson, C.D.1    Ray, G.J.2    DeWitt, M.A.3    Curie, G.L.4    Corn, J.E.5
  • 18
    • 84971006562 scopus 로고    scopus 로고
    • Programmable editing of a target base in genomic DNA without double-stranded DNA cleavage
    • Komor, A. C., Kim, Y. B., Packer, M. S., Zuris, J. A., and Liu, D. R. (2016) Programmable editing of a target base in genomic DNA without double-stranded DNA cleavage Nature 533, 420-424 10.1038/nature17946
    • (2016) Nature , vol.533 , pp. 420-424
    • Komor, A.C.1    Kim, Y.B.2    Packer, M.S.3    Zuris, J.A.4    Liu, D.R.5
  • 20
    • 84990898361 scopus 로고    scopus 로고
    • Targeted AID-mediated mutagenesis (TAM) enables efficient genomic diversification in mammalian cells
    • Ma, Y., Zhang, J., Yin, W., Zhang, Z., Song, Y., and Chang, X. (2016) Targeted AID-mediated mutagenesis (TAM) enables efficient genomic diversification in mammalian cells Nat. Methods 13, 1029-1035 10.1038/nmeth.4027
    • (2016) Nat. Methods , vol.13 , pp. 1029-1035
    • Ma, Y.1    Zhang, J.2    Yin, W.3    Zhang, Z.4    Song, Y.5    Chang, X.6
  • 24
    • 0026704096 scopus 로고
    • Strand-Specificity in the Transformation of Yeast with Synthetic Oligonucleotides
    • Yamamoto, T., Moerschell, R. P., Wakem, L. P., Komar-Panicucci, S., and Sherman, F. (1992) Strand-Specificity in the Transformation of Yeast with Synthetic Oligonucleotides Genetics 131, 811-819
    • (1992) Genetics , vol.131 , pp. 811-819
    • Yamamoto, T.1    Moerschell, R.P.2    Wakem, L.P.3    Komar-Panicucci, S.4    Sherman, F.5
  • 25
    • 0027958570 scopus 로고
    • The frequency of gene targeting in yeast depends on the number of target copies
    • Wilson, J. H., Leung, W. Y., Bosco, G., Dieu, D., and Haber, J. E. (1994) The frequency of gene targeting in yeast depends on the number of target copies Proc. Natl. Acad. Sci. U. S. A. 91, 177-181 10.1073/pnas.91.1.177
    • (1994) Proc. Natl. Acad. Sci. U. S. A. , vol.91 , pp. 177-181
    • Wilson, J.H.1    Leung, W.Y.2    Bosco, G.3    Dieu, D.4    Haber, J.E.5
  • 26
    • 0029892249 scopus 로고    scopus 로고
    • Targeted gene correction of episomal DNA in mammalian cells mediated by a chimeric RNA.DNA oligonucleotide
    • Yoon, K., Cole-Strauss, A., and Kmiec, E. B. (1996) Targeted gene correction of episomal DNA in mammalian cells mediated by a chimeric RNA.DNA oligonucleotide Proc. Natl. Acad. Sci. U. S. A. 93, 2071-2076 10.1073/pnas.93.5.2071
    • (1996) Proc. Natl. Acad. Sci. U. S. A. , vol.93 , pp. 2071-2076
    • Yoon, K.1    Cole-Strauss, A.2    Kmiec, E.B.3
  • 27
    • 0028104850 scopus 로고
    • The REC2 gene encodes the homologous pairing protein of Ustilago maydis
    • Kmiec, E. B., Cole, A., and Holloman, W. K. (1994) The REC2 gene encodes the homologous pairing protein of Ustilago maydis Mol. Cell. Biol. 14, 7163-7172 10.1128/MCB.14.11.7163
    • (1994) Mol. Cell. Biol. , vol.14 , pp. 7163-7172
    • Kmiec, E.B.1    Cole, A.2    Holloman, W.K.3
  • 29
    • 0029817766 scopus 로고    scopus 로고
    • Correction of the Mutation Responsible for Sickle Cell Anemia by an RNA-DNA Oligonucleotide
    • Cole-Strauss, A., Yoon, K., Xiang, Y., Byrne, B. C., Rice, M. C., Gryn, J., Holloman, W. K., and Kmiec, E. B. (1996) Correction of the Mutation Responsible for Sickle Cell Anemia by an RNA-DNA Oligonucleotide Science 273, 1386-1389 10.1126/science.273.5280.1386
    • (1996) Science , vol.273 , pp. 1386-1389
    • Cole-Strauss, A.1    Yoon, K.2    Xiang, Y.3    Byrne, B.C.4    Rice, M.C.5    Gryn, J.6    Holloman, W.K.7    Kmiec, E.B.8
  • 30
    • 0030913556 scopus 로고    scopus 로고
    • Targeted nucleotide exchange in the alkaline phosphatase gene of HuH-7 cells mediated by a chimeric RNA/DNA oligonucleotide
    • Kren, B. T., Cole-Strauss, A., Kmiec, E. B., and Steer, C. J. (1997) Targeted nucleotide exchange in the alkaline phosphatase gene of HuH-7 cells mediated by a chimeric RNA/DNA oligonucleotide Hepatology 25, 1462-1468 10.1002/hep.510250626
    • (1997) Hepatology , vol.25 , pp. 1462-1468
    • Kren, B.T.1    Cole-Strauss, A.2    Kmiec, E.B.3    Steer, C.J.4
  • 31
    • 0031734471 scopus 로고    scopus 로고
    • Stable and inheritable changes in genotype and phenotype of albino melanocytes induced by an RNA-DNA oligonucleotide
    • Alexeev, V. and Yoon, K. (1998) Stable and inheritable changes in genotype and phenotype of albino melanocytes induced by an RNA-DNA oligonucleotide Nat. Biotechnol. 16, 1343-1346 10.1038/4322
    • (1998) Nat. Biotechnol. , vol.16 , pp. 1343-1346
    • Alexeev, V.1    Yoon, K.2
  • 32
    • 0033989521 scopus 로고    scopus 로고
    • Localized in vivo genotypic and phenotypic correction of the albino mutation in skin by RNA-DNA oligonucleotide
    • Alexeev, V., Igoucheva, O., Domashenko, A., Cotsarelis, G., and Yoon, K. (2000) Localized in vivo genotypic and phenotypic correction of the albino mutation in skin by RNA-DNA oligonucleotide Nat. Biotechnol. 18, 43-47 10.1038/71901
    • (2000) Nat. Biotechnol. , vol.18 , pp. 43-47
    • Alexeev, V.1    Igoucheva, O.2    Domashenko, A.3    Cotsarelis, G.4    Yoon, K.5
  • 34
    • 0037705453 scopus 로고    scopus 로고
    • Transcription affects formation and processing of intermediates in oligonucleotide-mediated gene alteration
    • Igoucheva, O., Alexeev, V., Pryce, M., and Yoon, K. (2003) Transcription affects formation and processing of intermediates in oligonucleotide-mediated gene alteration Nucleic Acids Res. 31, 2659-2670 10.1093/nar/gkg360
    • (2003) Nucleic Acids Res. , vol.31 , pp. 2659-2670
    • Igoucheva, O.1    Alexeev, V.2    Pryce, M.3    Yoon, K.4
  • 35
    • 0036097061 scopus 로고    scopus 로고
    • Strand Bias in Targeted Gene Repair Is Influenced by Transcriptional Activity
    • Liu, L., Rice, M. C., Drury, M., Cheng, S., Gamper, H., and Kmiec, E. B. (2002) Strand Bias in Targeted Gene Repair Is Influenced by Transcriptional Activity Mol. Cell. Biol. 22, 3852-3863 10.1128/MCB.22.11.3852-3863.2002
    • (2002) Mol. Cell. Biol. , vol.22 , pp. 3852-3863
    • Liu, L.1    Rice, M.C.2    Drury, M.3    Cheng, S.4    Gamper, H.5    Kmiec, E.B.6
  • 36
    • 4444335574 scopus 로고    scopus 로고
    • DNA replication and transcription direct a DNA strand bias in the process of targeted gene repair in mammalian cells
    • Brachman, E. E. and Kmiec, E. B. (2004) DNA replication and transcription direct a DNA strand bias in the process of targeted gene repair in mammalian cells J. Cell Sci. 117, 3867 10.1242/jcs.01250
    • (2004) J. Cell Sci. , vol.117 , pp. 3867
    • Brachman, E.E.1    Kmiec, E.B.2
  • 37
    • 3242730327 scopus 로고    scopus 로고
    • Oligonucleotide-Directed Mutagenesis and Targeted Gene Correction: A Mechanistic Point of View
    • Igoucheva, O., Alexeev, V., and Yoon, K. (2004) Oligonucleotide-Directed Mutagenesis and Targeted Gene Correction: A Mechanistic Point of View Curr. Mol. Med. 4, 445-463 10.2174/1566524043360465
    • (2004) Curr. Mol. Med. , vol.4 , pp. 445-463
    • Igoucheva, O.1    Alexeev, V.2    Yoon, K.3
  • 39
    • 0033587679 scopus 로고    scopus 로고
    • A tool for functional plant genomics: Chimeric RNA/DNA oligonucleotides cause in vivo gene-specific mutations
    • Beetham, P. R., Kipp, P. B., Sawycky, X. L., Arntzen, C. J., and May, G. D. (1999) A tool for functional plant genomics: Chimeric RNA/DNA oligonucleotides cause in vivo gene-specific mutations Proc. Natl. Acad. Sci. U. S. A. 96, 8774-8778 10.1073/pnas.96.15.8774
    • (1999) Proc. Natl. Acad. Sci. U. S. A. , vol.96 , pp. 8774-8778
    • Beetham, P.R.1    Kipp, P.B.2    Sawycky, X.L.3    Arntzen, C.J.4    May, G.D.5
  • 40
    • 0037648962 scopus 로고    scopus 로고
    • Chimeric RNA/DNA Oligonucleotide-Based Site-Specific Modification of the Tobacco Acetolactate Syntase Gene
    • Kochevenko, A. and Willmitzer, L. (2003) Chimeric RNA/DNA Oligonucleotide-Based Site-Specific Modification of the Tobacco Acetolactate Syntase Gene Plant Physiol. 132, 174-184 10.1104/pp.102.016857
    • (2003) Plant Physiol. , vol.132 , pp. 174-184
    • Kochevenko, A.1    Willmitzer, L.2
  • 42
    • 0034122866 scopus 로고    scopus 로고
    • Engineering herbicide-resistant maize using chimeric RNA/DNA oligonucleotides
    • Zhu, T., Mettenburg, K., Peterson, D. J., Tagliani, L., and Baszczynski, C. L. (2000) Engineering herbicide-resistant maize using chimeric RNA/DNA oligonucleotides Nat. Biotechnol. 18, 555-558 10.1038/75435
    • (2000) Nat. Biotechnol. , vol.18 , pp. 555-558
    • Zhu, T.1    Mettenburg, K.2    Peterson, D.J.3    Tagliani, L.4    Baszczynski, C.L.5
  • 43
    • 1242298958 scopus 로고    scopus 로고
    • Chimeric RNA/DNA oligonucleotide-directed gene targeting in rice
    • Okuzaki, A. and Toriyama, K. (2004) Chimeric RNA/DNA oligonucleotide-directed gene targeting in rice Plant Cell Rep. 22, 509-512 10.1007/s00299-003-0698-2
    • (2004) Plant Cell Rep. , vol.22 , pp. 509-512
    • Okuzaki, A.1    Toriyama, K.2
  • 44
    • 33645957355 scopus 로고    scopus 로고
    • Oligonucleotide-directed gene repair in wheat using a transient plasmid gene repair assay system
    • Dong, C., Beetham, P., Vincent, K., and Sharp, P. (2006) Oligonucleotide-directed gene repair in wheat using a transient plasmid gene repair assay system Plant Cell Rep. 25, 457-465 10.1007/s00299-005-0098-x
    • (2006) Plant Cell Rep. , vol.25 , pp. 457-465
    • Dong, C.1    Beetham, P.2    Vincent, K.3    Sharp, P.4
  • 46
    • 84955342519 scopus 로고    scopus 로고
    • New Technologies for Insect-Resistant and Herbicide-Tolerant Plants
    • Lombardo, L., Coppola, G., and Zelasco, S. (2016) New Technologies for Insect-Resistant and Herbicide-Tolerant Plants Trends Biotechnol. 34, 49-57 10.1016/j.tibtech.2015.10.006
    • (2016) Trends Biotechnol. , vol.34 , pp. 49-57
    • Lombardo, L.1    Coppola, G.2    Zelasco, S.3
  • 47
    • 0034903337 scopus 로고    scopus 로고
    • In vivo site-directed mutagenesis using oligonucleotides
    • Storici, F., Lewis, L. K., and Resnick, M. A. (2001) In vivo site-directed mutagenesis using oligonucleotides Nat. Biotechnol. 19, 773-776 10.1038/90837
    • (2001) Nat. Biotechnol. , vol.19 , pp. 773-776
    • Storici, F.1    Lewis, L.K.2    Resnick, M.A.3
  • 48
    • 33745225170 scopus 로고    scopus 로고
    • The Delitto Perfetto Approach to in Vivo Site-Directed Mutagenesis and Chromosome Rearrangements with Synthetic Oligonucleotides in Yeast
    • Academic Press
    • Storici, F. and Resnick, M. A. (2006) The Delitto Perfetto Approach to In Vivo Site-Directed Mutagenesis and Chromosome Rearrangements with Synthetic Oligonucleotides in Yeast, In Methods in Enzymology, pp 329-345, Academic Press.
    • (2006) Methods in Enzymology , pp. 329-345
    • Storici, F.1    Resnick, M.A.2
  • 49
    • 84898985341 scopus 로고    scopus 로고
    • Aptamer-guided gene targeting in yeast and human cells
    • Ruff, P., Koh, K. D., Keskin, H., Pai, R. B., and Storici, F. (2014) Aptamer-guided gene targeting in yeast and human cells Nucleic Acids Res. 42, e61-e61 10.1093/nar/gku101
    • (2014) Nucleic Acids Res. , vol.42 , pp. e61-e61
    • Ruff, P.1    Koh, K.D.2    Keskin, H.3    Pai, R.B.4    Storici, F.5
  • 50
    • 84895897031 scopus 로고    scopus 로고
    • To Nick or Not to Nick: Comparison of I-SceI Single- and Double-Strand Break-Induced Recombination in Yeast and Human Cells
    • Katz, S. S., Gimble, F. S., and Storici, F. (2014) To Nick or Not to Nick: Comparison of I-SceI Single- and Double-Strand Break-Induced Recombination in Yeast and Human Cells PLoS One 9, e88840 10.1371/journal.pone.0088840
    • (2014) PLoS One , vol.9 , pp. e88840
    • Katz, S.S.1    Gimble, F.S.2    Storici, F.3
  • 52
    • 38049125557 scopus 로고    scopus 로고
    • Mechanisms and functions of DNA mismatch repair
    • Li, G.-M. (2008) Mechanisms and functions of DNA mismatch repair Cell Res. 18, 85-98 10.1038/cr.2007.115
    • (2008) Cell Res. , vol.18 , pp. 85-98
    • Li, G.-M.1
  • 53
    • 85018935232 scopus 로고    scopus 로고
    • Genome-wide target specificities of CRISPR RNA-guided programmable deaminases
    • Kim, D., Lim, K., Kim, S.-T., Yoon, S.-h., Kim, K., Ryu, S.-M., and Kim, J.-S. (2017) Genome-wide target specificities of CRISPR RNA-guided programmable deaminases Nat. Biotechnol. 35, 475-480 10.1038/nbt.3852
    • (2017) Nat. Biotechnol. , vol.35 , pp. 475-480
    • Kim, D.1    Lim, K.2    Kim, S.-T.3    Yoon, S.-H.4    Kim, K.5    Ryu, S.-M.6    Kim, J.-S.7
  • 54
    • 85020458044 scopus 로고    scopus 로고
    • Improving the DNA specificity and applicability of base editing through protein engineering and protein delivery
    • Rees, H. A., Komor, A. C., Yeh, W.-H., Caetano-Lopes, J., Warman, M., Edge, A. S. B., and Liu, D. R. (2017) Improving the DNA specificity and applicability of base editing through protein engineering and protein delivery Nat. Commun. 8, 15790 10.1038/ncomms15790
    • (2017) Nat. Commun. , vol.8 , pp. 15790
    • Rees, H.A.1    Komor, A.C.2    Yeh, W.-H.3    Caetano-Lopes, J.4    Warman, M.5    Edge, A.S.B.6    Liu, D.R.7
  • 56
    • 85025611746 scopus 로고    scopus 로고
    • Programmable base editing of zebrafish genome using a modified CRISPR-Cas9 system
    • Zhang, Y., Qin, W., Lu, X., Xu, J., Huang, H., Bai, H., Li, S., and Lin, S. (2017) Programmable base editing of zebrafish genome using a modified CRISPR-Cas9 system Nat. Commun. 8, 118 10.1038/s41467-017-00175-6
    • (2017) Nat. Commun. , vol.8 , pp. 118
    • Zhang, Y.1    Qin, W.2    Lu, X.3    Xu, J.4    Huang, H.5    Bai, H.6    Li, S.7    Lin, S.8
  • 57
    • 85030701188 scopus 로고    scopus 로고
    • Improved Base Excision Repair Inhibition and Bacteriophage Mu Gam Protein Yields C:G-to-T:A Base Editors with Higher Efficiency and Product Purity
    • Komor, A. C., Zhao, K. T., Packer, M. S., Gaudelli, N. M., Waterbury, A. L., Koblan, L. W., Kim, Y. B., Badran, A. H., and Liu, D. R. (2017) Improved Base Excision Repair Inhibition and Bacteriophage Mu Gam Protein Yields C:G-to-T:A Base Editors with Higher Efficiency and Product Purity Science Advances 3, eaao4774 10.1126/sciadv.aao4774
    • (2017) Science Advances , vol.3 , pp. eaao4774
    • Komor, A.C.1    Zhao, K.T.2    Packer, M.S.3    Gaudelli, N.M.4    Waterbury, A.L.5    Koblan, L.W.6    Kim, Y.B.7    Badran, A.H.8    Liu, D.R.9
  • 58
    • 85027502168 scopus 로고    scopus 로고
    • CRISPR-STOP: Gene silencing through base-editing-induced nonsense mutations
    • Kuscu, C., Parlak, M., Tufan, T., Yang, J., Szlachta, K., Wei, X., Mammadov, R., and Adli, M. (2017) CRISPR-STOP: gene silencing through base-editing-induced nonsense mutations Nat. Methods 14, 710-712 10.1038/nmeth.4327
    • (2017) Nat. Methods , vol.14 , pp. 710-712
    • Kuscu, C.1    Parlak, M.2    Tufan, T.3    Yang, J.4    Szlachta, K.5    Wei, X.6    Mammadov, R.7    Adli, M.8
  • 59
    • 85030254880 scopus 로고    scopus 로고
    • CRISPR-Mediated Base Editing Enables Efficient Disruption of Eukaryotic Genes Through Induction of Stop Codons (iSTOP)
    • Billon, P., Bryant, E. E., Joseph, S. A., Nambiar, T. S., Hayward, S. B., Rothstein, R., and Ciccia, A. (2017) CRISPR-Mediated Base Editing Enables Efficient Disruption of Eukaryotic Genes Through Induction of Stop Codons (iSTOP) Mol. Cell 67, 1068 10.1016/j.molcel.2017.08.008
    • (2017) Mol. Cell , vol.67 , pp. 1068
    • Billon, P.1    Bryant, E.E.2    Joseph, S.A.3    Nambiar, T.S.4    Hayward, S.B.5    Rothstein, R.6    Ciccia, A.7
  • 60
    • 85021648932 scopus 로고    scopus 로고
    • Aptazyme-embedded guide RNAs enable ligand-responsive genome editing and transcriptional activation
    • Tang, W., Hu, J. H., and Liu, D. R. (2017) Aptazyme-embedded guide RNAs enable ligand-responsive genome editing and transcriptional activation Nat. Commun. 8, 15939 10.1038/ncomms15939
    • (2017) Nat. Commun. , vol.8 , pp. 15939
    • Tang, W.1    Hu, J.H.2    Liu, D.R.3
  • 61
    • 85017397628 scopus 로고    scopus 로고
    • Increasing the genome-targeting scope and precision of base editing with engineered Cas9-cytidine deaminase fusions
    • Kim, Y. B., Komor, A. C., Levy, J. M., Packer, M. S., Zhao, K. T., and Liu, D. R. (2017) Increasing the genome-targeting scope and precision of base editing with engineered Cas9-cytidine deaminase fusions Nat. Biotechnol. 35, 371-376 10.1038/nbt.3803
    • (2017) Nat. Biotechnol. , vol.35 , pp. 371-376
    • Kim, Y.B.1    Komor, A.C.2    Levy, J.M.3    Packer, M.S.4    Zhao, K.T.5    Liu, D.R.6
  • 62
    • 85009355218 scopus 로고    scopus 로고
    • Precise Editing of a Target Base in the Rice Genome Using a Modified CRISPR/Cas9 System
    • Lu, Y. and Zhu, J.-K. (2017) Precise Editing of a Target Base in the Rice Genome Using a Modified CRISPR/Cas9 System Mol. Plant 10, 523-525 10.1016/j.molp.2016.11.013
    • (2017) Mol. Plant , vol.10 , pp. 523-525
    • Lu, Y.1    Zhu, J.-K.2
  • 63
    • 85009243700 scopus 로고    scopus 로고
    • Generation of Targeted Point Mutations in Rice by a Modified CRISPR/Cas9 System
    • Li, J., Sun, Y., Du, J., Zhao, Y., and Xia, L. (2017) Generation of Targeted Point Mutations in Rice by a Modified CRISPR/Cas9 System Mol. Plant 10, 526-529 10.1016/j.molp.2016.12.001
    • (2017) Mol. Plant , vol.10 , pp. 526-529
    • Li, J.1    Sun, Y.2    Du, J.3    Zhao, Y.4    Xia, L.5
  • 64
    • 85018618268 scopus 로고    scopus 로고
    • Precise base editing in rice, wheat and maize with a Cas9-cytidine deaminase fusion
    • Zong, Y., Wang, Y., Li, C., Zhang, R., Chen, K., Ran, Y., Qiu, J.-L., Wang, D., and Gao, C. (2017) Precise base editing in rice, wheat and maize with a Cas9-cytidine deaminase fusion Nat. Biotechnol. 35, 438-440 10.1038/nbt.3811
    • (2017) Nat. Biotechnol. , vol.35 , pp. 438-440
    • Zong, Y.1    Wang, Y.2    Li, C.3    Zhang, R.4    Chen, K.5    Ran, Y.6    Qiu, J.-L.7    Wang, D.8    Gao, C.9
  • 69
    • 84976869384 scopus 로고    scopus 로고
    • RMBase: A resource for decoding the landscape of RNA modifications from high-throughput sequencing data
    • Sun, W.-J., Li, J.-H., Liu, S., Wu, J., Zhou, H., Qu, L.-H., and Yang, J.-H. (2016) RMBase: a resource for decoding the landscape of RNA modifications from high-throughput sequencing data Nucleic Acids Res. 44, D259-D265 10.1093/nar/gkv1036
    • (2016) Nucleic Acids Res. , vol.44 , pp. D259-D265
    • Sun, W.-J.1    Li, J.-H.2    Liu, S.3    Wu, J.4    Zhou, H.5    Qu, L.-H.6    Yang, J.-H.7
  • 73
    • 85011392399 scopus 로고    scopus 로고
    • Construction of a guide-RNA for site-directed RNA mutagenesis utilising intracellular A-to-I RNA editing
    • Fukuda, M., Umeno, H., Nose, K., Nishitarumizu, A., Noguchi, R., and Nakagawa, H. (2017) Construction of a guide-RNA for site-directed RNA mutagenesis utilising intracellular A-to-I RNA editing Sci. Rep. 7, 41478 10.1038/srep41478
    • (2017) Sci. Rep. , vol.7 , pp. 41478
    • Fukuda, M.1    Umeno, H.2    Nose, K.3    Nishitarumizu, A.4    Noguchi, R.5    Nakagawa, H.6
  • 74
    • 84887300101 scopus 로고    scopus 로고
    • Correction of mutations within the cystic fibrosis transmembrane conductance regulator by site-directed RNA editing
    • Montiel-Gonzalez, M. F., Vallecillo-Viejo, I., Yudowski, G. A., and Rosenthal, J. J. C. (2013) Correction of mutations within the cystic fibrosis transmembrane conductance regulator by site-directed RNA editing Proc. Natl. Acad. Sci. U. S. A. 110, 18285-18290 10.1073/pnas.1306243110
    • (2013) Proc. Natl. Acad. Sci. U. S. A. , vol.110 , pp. 18285-18290
    • Montiel-Gonzalez, M.F.1    Vallecillo-Viejo, I.2    Yudowski, G.A.3    Rosenthal, J.J.C.4
  • 75
    • 84867835332 scopus 로고    scopus 로고
    • An RNA-Deaminase Conjugate Selectively Repairs Point Mutations
    • Stafforst, T. and Schneider, M. F. (2012) An RNA-Deaminase Conjugate Selectively Repairs Point Mutations Angew. Chem., Int. Ed. 51, 11166-11169 10.1002/anie.201206489
    • (2012) Angew. Chem., Int. Ed. , vol.51 , pp. 11166-11169
    • Stafforst, T.1    Schneider, M.F.2
  • 76
    • 85016148680 scopus 로고    scopus 로고
    • An efficient system for selectively altering genetic information within mRNAs
    • Montiel-González, M. F., Vallecillo-Viejo, I. C., and Rosenthal, J. J. C. (2016) An efficient system for selectively altering genetic information within mRNAs Nucleic Acids Res. 44, gkw738 10.1093/nar/gkw738
    • (2016) Nucleic Acids Res. , vol.44 , pp. gkw738
    • Montiel-González, M.F.1    Vallecillo-Viejo, I.C.2    Rosenthal, J.J.C.3
  • 77
    • 84903209128 scopus 로고    scopus 로고
    • Optimal guideRNAs for re-directing deaminase activity of hADAR1 and hADAR2 in trans
    • Schneider, M. F., Wettengel, J., Hoffmann, P. C., and Stafforst, T. (2014) Optimal guideRNAs for re-directing deaminase activity of hADAR1 and hADAR2 in trans Nucleic Acids Res. 42, e87-e87 10.1093/nar/gku272
    • (2014) Nucleic Acids Res. , vol.42 , pp. e87-e87
    • Schneider, M.F.1    Wettengel, J.2    Hoffmann, P.C.3    Stafforst, T.4
  • 78
    • 84902201236 scopus 로고    scopus 로고
    • Improving Site-Directed RNA Editing in Vitro and in Cell Culture by Chemical Modification of the GuideRNA
    • Vogel, P., Schneider, M. F., Wettengel, J., and Stafforst, T. (2014) Improving Site-Directed RNA Editing In Vitro and in Cell Culture by Chemical Modification of the GuideRNA Angew. Chem., Int. Ed. 53, 6267-6271 10.1002/anie.201402634
    • (2014) Angew. Chem., Int. Ed. , vol.53 , pp. 6267-6271
    • Vogel, P.1    Schneider, M.F.2    Wettengel, J.3    Stafforst, T.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.