Programmable base editing of zebrafish genome using a modified CRISPR-Cas9 system

Nature Communications

Volumn 8, Issue 1, 2017, Pages

  Zhang, Yihan ^a,b   Qin, Wei ^a   Lu, Xiaochan ^a   Xu, Jason ^b   Huang, Haigen ^b   Bai, Haipeng ^a   Li, Song ^a   Lin, Shuo ^a,b  

^a PEKING UNIVERSITY   (China)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYTIDINE DEAMINASE; GENOMIC DNA; GROWTH DIFFERENTIATION FACTOR 6; LEUCINE; MESSENGER RNA; PROLINE; BRACHYURY PROTEIN; FETOPROTEIN; GDF6A PROTEIN, ZEBRAFISH; T BOX TRANSCRIPTION FACTOR; ZEBRAFISH PROTEIN;

CYPRINID; GENE; GENETIC ENGINEERING; GENOME; MUTATION; RNA;

AMINO ACID SUBSTITUTION; ANIMAL EXPERIMENT; ARTICLE; CRISPR CAS SYSTEM; EMBRYO; GENE EDITING; GENE LOCUS; GENOME; IN VITRO STUDY; INDEL MUTATION; NONHUMAN; NUCLEIC ACID BASE SUBSTITUTION; PHENOTYPE; POINT MUTATION; PROGRAMMABLE BASE EDITING; ZEBRA FISH; AMINO ACID SEQUENCE; ANIMAL; GENETIC ENGINEERING; GENETICS; NUCLEOTIDE SEQUENCE; PROCEDURES; REPRODUCIBILITY; SEQUENCE HOMOLOGY; SITE DIRECTED MUTAGENESIS;

ANIMALIA; DANIO RERIO;

AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; CRISPR-CAS SYSTEMS; FETAL PROTEINS; GENE EDITING; GENETIC ENGINEERING; GROWTH DIFFERENTIATION FACTOR 6; MUTAGENESIS, SITE-DIRECTED; POINT MUTATION; REPRODUCIBILITY OF RESULTS; SEQUENCE HOMOLOGY, AMINO ACID; SEQUENCE HOMOLOGY, NUCLEIC ACID; T-BOX DOMAIN PROTEINS; ZEBRAFISH; ZEBRAFISH PROTEINS;

EID: 85025611746     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/s41467-017-00175-6     Document Type: Article

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