메뉴 건너뛰기




Volumn 38, Issue C, 1998, Pages 185-218

5 DNA Breakage and Repair

Author keywords

[No Author keywords available]

Indexed keywords

DNA BINDING PROTEIN; DNA DEPENDENT PROTEIN KINASE; NUCLEAR PROTEIN; PRKDC PROTEIN, HUMAN; PROTEIN SERINE THREONINE KINASE; XRCC4 PROTEIN, HUMAN;

EID: 0031607707     PISSN: 00652660     EISSN: None     Source Type: Book Series    
DOI: 10.1016/S0065-2660(08)60144-3     Document Type: Article
Times cited : (317)

References (152)
  • 2
    • 0027490279 scopus 로고
    • DNA damage and the DNA-activated protein kinase
    • Anderson C.W. DNA damage and the DNA-activated protein kinase. Trends Biochem. Sci. 18 (1993) 433-437
    • (1993) Trends Biochem. Sci. , vol.18 , pp. 433-437
    • Anderson, C.W.1
  • 4
    • 0021306021 scopus 로고
    • Deficient recovery from potentially lethal damage in some gamma-irradiated human fibroblast cell strains
    • Arlett C., and Priestley A.F. Deficient recovery from potentially lethal damage in some gamma-irradiated human fibroblast cell strains. Brt. J. Cancer 49 Suppl. VI (1984) 227-232
    • (1984) Brt. J. Cancer , vol.49 , Issue.SUPPL. VI , pp. 227-232
    • Arlett, C.1    Priestley, A.F.2
  • 5
    • 0029945097 scopus 로고    scopus 로고
    • A double-strand break within a yeast artificial chromosome (YAC) containing human DNA can result in YAC loss, deletion, or cell lethality
    • Bennett C.B., Westmoreland T.J., Snipe J.R., and Resnick M.A. A double-strand break within a yeast artificial chromosome (YAC) containing human DNA can result in YAC loss, deletion, or cell lethality. Mol. Cell. Biol. 16 (1996) 4414-4425
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 4414-4425
    • Bennett, C.B.1    Westmoreland, T.J.2    Snipe, J.R.3    Resnick, M.A.4
  • 7
    • 0026071588 scopus 로고
    • Scid mutation in mice confers hypersensitivity to ionizing radiation and a deficiency in DNA double-strand break repair
    • Biedermann K.A., Sun J., Giaccia A.J., Tosto L.M., and Brown J.M. Scid mutation in mice confers hypersensitivity to ionizing radiation and a deficiency in DNA double-strand break repair. Proc. Natl. Acad. Sci. USA 88 (1991) 1394-1397
    • (1991) Proc. Natl. Acad. Sci. USA , vol.88 , pp. 1394-1397
    • Biedermann, K.A.1    Sun, J.2    Giaccia, A.J.3    Tosto, L.M.4    Brown, J.M.5
  • 8
    • 0027468265 scopus 로고
    • Binding of Ku protein to DNA. Measurement of affinity for ends and demonstration of binding to nicks
    • Blier P.R., Griffith A.J., Craft J., and Hardin J.A. Binding of Ku protein to DNA. Measurement of affinity for ends and demonstration of binding to nicks. J. Biol. Chem. 268 (1993) 7594-7601
    • (1993) J. Biol. Chem. , vol.268 , pp. 7594-7601
    • Blier, P.R.1    Griffith, A.J.2    Craft, J.3    Hardin, J.A.4
  • 10
    • 0029788520 scopus 로고    scopus 로고
    • Identification of a nonsense mutation in the carboxy-terminal region of DNA-dependent protein kinase catalytic subunit in the scid mouse
    • Blunt T., Gell D., Fox M., Taccioli G.E., Jackson S.P., Lehmann A.R., and Jeggo P.A. Identification of a nonsense mutation in the carboxy-terminal region of DNA-dependent protein kinase catalytic subunit in the scid mouse. Proc. Natl. Acad. Sci. USA 93 (1996) 10285-10290
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 10285-10290
    • Blunt, T.1    Gell, D.2    Fox, M.3    Taccioli, G.E.4    Jackson, S.P.5    Lehmann, A.R.6    Jeggo, P.A.7
  • 11
    • 0020663062 scopus 로고
    • A severe combined immunodeficiency mutation in the mouse
    • Bosma G.C., Custer R.P., and Bosma M.J. A severe combined immunodeficiency mutation in the mouse. Nature 301 (1983) 527-530
    • (1983) Nature , vol.301 , pp. 527-530
    • Bosma, G.C.1    Custer, R.P.2    Bosma, M.J.3
  • 12
    • 0025811882 scopus 로고
    • The SCID mouse mutant: Definition, characterization and potential uses
    • Bosma M.J., and Carroll A.M. The SCID mouse mutant: Definition, characterization and potential uses. Annu. Rev. Immunol. 9 (1991) 323-350
    • (1991) Annu. Rev. Immunol. , vol.9 , pp. 323-350
    • Bosma, M.J.1    Carroll, A.M.2
  • 14
    • 0029843408 scopus 로고    scopus 로고
    • Identification of a Saccharomyces cerevisiae homologue: Roles in DNA double-strand break repair and telometic maintenance
    • Boulton S.J., and Jackson S.P. Identification of a Saccharomyces cerevisiae homologue: Roles in DNA double-strand break repair and telometic maintenance. Nucleic Acids Res. 24 (1996) 4639-4648
    • (1996) Nucleic Acids Res. , vol.24 , pp. 4639-4648
    • Boulton, S.J.1    Jackson, S.P.2
  • 17
    • 0023635562 scopus 로고
    • High chromosomal sensitivity of Chinese hamster xrs5 cells to restriction endonuclease induced DNA double-strand breaks
    • Bryant P.E., Birch D.A., and Jeggo P.A. High chromosomal sensitivity of Chinese hamster xrs5 cells to restriction endonuclease induced DNA double-strand breaks. Int. J. Radiat. Biol 52 (1987) 537-554
    • (1987) Int. J. Radiat. Biol , vol.52 , pp. 537-554
    • Bryant, P.E.1    Birch, D.A.2    Jeggo, P.A.3
  • 18
    • 0028158320 scopus 로고
    • Chromosomal location and expression of the genes coding for Ku p70 and p80 in human cell lines and normal tissues
    • Cai Q.-Q., Plet III A., Lafage-Pochitaloff J.M., Cerdan, and Blanchard J.-M. Chromosomal location and expression of the genes coding for Ku p70 and p80 in human cell lines and normal tissues. Cytogenet. Cell Genet. 65 (1994) 221-227
    • (1994) Cytogenet. Cell Genet. , vol.65 , pp. 221-227
    • Cai, Q.-Q.1    Plet III, A.2    Lafage-Pochitaloff, J.M.3    Cerdan4    Blanchard, J.-M.5
  • 19
    • 0031031787 scopus 로고    scopus 로고
    • From BRCA1 to RAP1: A widespread BRCT module closely associated with DNA repair
    • Callebaut I Mornon J.P. From BRCA1 to RAP1: A widespread BRCT module closely associated with DNA repair. FEBS Lett. 400 (1997) 25-30
    • (1997) FEBS Lett. , vol.400 , pp. 25-30
    • Callebaut I Mornon, J.P.1
  • 20
    • 0028141785 scopus 로고
    • Dna-dependent ATPase from He La-cells is related to human Ku autoantigen
    • Cao Q.P., Pitt S., Leszyk J., and Baril E.F. Dna-dependent ATPase from He La-cells is related to human Ku autoantigen. Biochemistry 33 (1994) 8548-8557
    • (1994) Biochemistry , vol.33 , pp. 8548-8557
    • Cao, Q.P.1    Pitt, S.2    Leszyk, J.3    Baril, E.F.4
  • 21
    • 0027404942 scopus 로고
    • Increased radiosensitivity of granulocyte macrophage colony-forming units and skin fibroblasts in human autosomal recessive severe combined immunodeficiency
    • Cavazzana Calvo M., Le Deist E., De Saint Basile G., Papadopoulo D., De Villartay J.P., and Fischer A. Increased radiosensitivity of granulocyte macrophage colony-forming units and skin fibroblasts in human autosomal recessive severe combined immunodeficiency. J Clin. Invest. 91 (1993) 1214-1218
    • (1993) J Clin. Invest. , vol.91 , pp. 1214-1218
    • Cavazzana Calvo, M.1    Le Deist, E.2    De Saint Basile, G.3    Papadopoulo, D.4    De Villartay, J.P.5    Fischer, A.6
  • 22
    • 0030009738 scopus 로고    scopus 로고
    • The DNA-dependent protein kinase is inactivated by autophosphorylation of the catalytic subnit. J
    • Chan D.W., and Lees-Miller S.P. The DNA-dependent protein kinase is inactivated by autophosphorylation of the catalytic subnit. J. Biol. Chem. 271 (1996) 8936-8941
    • (1996) Biol. Chem. , vol.271 , pp. 8936-8941
    • Chan, D.W.1    Lees-Miller, S.P.2
  • 23
    • 0027512522 scopus 로고
    • Characterization of the DNA double strand break repair defect in scid mice
    • Chang C., Biedermann K.A., Mezzina M., and Brown J.M. Characterization of the DNA double strand break repair defect in scid mice. Cancer Res. 53 (1993) 1244-1248
    • (1993) Cancer Res. , vol.53 , pp. 1244-1248
    • Chang, C.1    Biedermann, K.A.2    Mezzina, M.3    Brown, J.M.4
  • 24
    • 0030041564 scopus 로고    scopus 로고
    • Disruption of DNA-PK in Ku80 mutant xrs-6 and the implication in DNA double-strand break repair
    • Chen F., Peterson III S.R., and Chen M.D.J.D. Disruption of DNA-PK in Ku80 mutant xrs-6 and the implication in DNA double-strand break repair. Mutat. Res. 362 (1996) 9-19
    • (1996) Mutat. Res. , vol.362 , pp. 9-19
    • Chen, F.1    Peterson III, S.R.2    Chen, M.D.J.D.3
  • 25
    • 0028366253 scopus 로고
    • Loss of S-phase-dependent radioresistance in irs-1 cells exposed to X-rays
    • Cheong N., Wang X., Wang Y., and Iliakis G. Loss of S-phase-dependent radioresistance in irs-1 cells exposed to X-rays. Mutat. Res. DNA Rep. 314 (1994) 77-85
    • (1994) Mutat. Res. DNA Rep. , vol.314 , pp. 77-85
    • Cheong, N.1    Wang, X.2    Wang, Y.3    Iliakis, G.4
  • 26
    • 0022729893 scopus 로고
    • Ataxia-telangiectasia-A human mutation giving high frequency misrepair of DNA double-stranded scissions
    • Cox R., Debenham III P.G., and Webb W.K.M.B.T. Ataxia-telangiectasia-A human mutation giving high frequency misrepair of DNA double-stranded scissions. Mol. Biol. Med. 3 (1986) 229-244
    • (1986) Mol. Biol. Med. , vol.3 , pp. 229-244
    • Cox, R.1    Debenham III, P.G.2    Webb, W.K.M.B.T.3
  • 27
    • 0031214080 scopus 로고    scopus 로고
    • Mammalian DNA double-strand break repair protein XRCC4 interacts with DNA ligase IV
    • Critchlow S.E., Bowater R.P., and Jackson S.P. Mammalian DNA double-strand break repair protein XRCC4 interacts with DNA ligase IV. Curr. Biol. 7 (1997) 588-598
    • (1997) Curr. Biol. , vol.7 , pp. 588-598
    • Critchlow, S.E.1    Bowater, R.P.2    Jackson, S.P.3
  • 28
    • 0022257878 scopus 로고
    • Severe combined immunodeficiency (SCID) in the mouse: Pathology, reconstitution, neoplasms
    • Custer III R.P., and Bosma G.M.J.C. Severe combined immunodeficiency (SCID) in the mouse: Pathology, reconstitution, neoplasms. Am. J. Pathol. 120 (1985) 464-477
    • (1985) Am. J. Pathol. , vol.120 , pp. 464-477
    • Custer III, R.P.1    Bosma, G.M.J.C.2
  • 29
    • 0029791450 scopus 로고    scopus 로고
    • Biochemical and genetic defects in the DNA-dependent protein kinase in murine scid lymphocytes
    • Danska J.S., Holland D.P., Mariathasan S., Williams K.M., and Guidos C.J. Biochemical and genetic defects in the DNA-dependent protein kinase in murine scid lymphocytes. Mol. Cell. Biol. 16 (1996) 5507-5517
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 5507-5517
    • Danska, J.S.1    Holland, D.P.2    Mariathasan, S.3    Williams, K.M.4    Guidos, C.J.5
  • 30
    • 0023946191 scopus 로고
    • Examination of vectors with two dominant, selectable genes for DNA repair and mutation studies in mammalian cells
    • Debenham P.G., Webb M.B., Stretch T.A., and Thacker J. Examination of vectors with two dominant, selectable genes for DNA repair and mutation studies in mammalian cells. Mutat. Res. 199 (1988) 145-158
    • (1988) Mutat. Res. , vol.199 , pp. 145-158
    • Debenham, P.G.1    Webb, M.B.2    Stretch, T.A.3    Thacker, J.4
  • 31
    • 0027048773 scopus 로고
    • Ku autoantigen is the regulatory component of a template-associated protein kinase that phosphorylates RNA polymerase II
    • Dvir A., Peterson III S.R., Lu M.W.H., and Dynan W.S. Ku autoantigen is the regulatory component of a template-associated protein kinase that phosphorylates RNA polymerase II. Proc. Natl. Acad. Sci. USA 89 (1992) 11920-11924
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 11920-11924
    • Dvir, A.1    Peterson III, S.R.2    Lu, M.W.H.3    Dynan, W.S.4
  • 33
    • 0029928176 scopus 로고    scopus 로고
    • Ku86 defines the genetic defect and restores X-ray resistance and V(D)J recombination to complementation group 5 hamster cell mutants
    • Errami III A., Rathmeli V.W.K., He D.M., Hendrickson E.A., Zdzienicka M.Z., and Chu G. Ku86 defines the genetic defect and restores X-ray resistance and V(D)J recombination to complementation group 5 hamster cell mutants. Mol. Cell. Biol. 16 (1996) 1519-1526
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 1519-1526
    • Errami III, A.1    Rathmeli, V.W.K.2    He, D.M.3    Hendrickson, E.A.4    Zdzienicka, M.Z.5    Chu, G.6
  • 35
    • 0027156140 scopus 로고
    • EBP-80, a transcription factor closely resembling the human autoantigen Ku, recognizes single- to double-strand transitions in DNA
    • Falzon M., Fewell J.W., and Kuff E.L. EBP-80, a transcription factor closely resembling the human autoantigen Ku, recognizes single- to double-strand transitions in DNA. J. Biol. Chem. 268 (1993) 10546-10552
    • (1993) J. Biol. Chem. , vol.268 , pp. 10546-10552
    • Falzon, M.1    Fewell, J.W.2    Kuff, E.L.3
  • 36
    • 0027288231 scopus 로고
    • A putative homologue of the human autoantigen Ku from Saccharomyces cerevisiae
    • Feldmann H., and Winnacker E.L. A putative homologue of the human autoantigen Ku from Saccharomyces cerevisiae. J. Biol. Chem. 268 (1993) 12895-12900
    • (1993) J. Biol. Chem. , vol.268 , pp. 12895-12900
    • Feldmann, H.1    Winnacker, E.L.2
  • 37
    • 0028897304 scopus 로고
    • DNA-dependent protein-kinase activity is absent in xrs-6 cells implications for site-specific recombination and dna double-strand break repair
    • Finnie N.J., Gottlieb T.M., Blunt T., Jeggo P.A., and Jackson S.P. DNA-dependent protein-kinase activity is absent in xrs-6 cells implications for site-specific recombination and dna double-strand break repair. Proc. Natl. Acad. Sci. USA 92 (1995) 320-324
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 320-324
    • Finnie, N.J.1    Gottlieb, T.M.2    Blunt, T.3    Jeggo, P.A.4    Jackson, S.P.5
  • 38
    • 0026498944 scopus 로고
    • Removal of nonhomologous DNA ends in double-strand break recombination: The role of the yeast ultraviolet repair gene RAD1
    • Fishman-Lobell J., and Haber J.E. Removal of nonhomologous DNA ends in double-strand break recombination: The role of the yeast ultraviolet repair gene RAD1. Science 258 (1992) 480-484
    • (1992) Science , vol.258 , pp. 480-484
    • Fishman-Lobell, J.1    Haber, J.E.2
  • 39
    • 0026583875 scopus 로고
    • Two alternative pathways of double-strand beak repair that are kinetically separable and independently modulated
    • Fishman-Lobell J., Rudin N., and Haber J. Two alternative pathways of double-strand beak repair that are kinetically separable and independently modulated. Mol. Cell. Biol. 12 (1992) 1292-1303
    • (1992) Mol. Cell. Biol. , vol.12 , pp. 1292-1303
    • Fishman-Lobell, J.1    Rudin, N.2    Haber, J.3
  • 40
    • 0029559791 scopus 로고
    • Dose-rate effect on induction and repair rate of radiation-induced DNA double-strand breaks in a normal and an ataxia-telangiectasia human fibroblast cell-line
    • Foray III N., and Malaise C.E.P.F. Dose-rate effect on induction and repair rate of radiation-induced DNA double-strand breaks in a normal and an ataxia-telangiectasia human fibroblast cell-line. Biochmie 77 (1995) 900-905
    • (1995) Biochmie , vol.77 , pp. 900-905
    • Foray III, N.1    Malaise, C.E.P.F.2
  • 41
    • 0030750923 scopus 로고    scopus 로고
    • Hypersensitivity of Ataxia-telangiectasia fibroblasts to ionizing radiation is associated with a repair deficiency of DNA double-strand breaks
    • Foray N., Priestley A., Alsbeih G., Badie C., Capulas III E.P., and Malaise C.E.P.F. Hypersensitivity of Ataxia-telangiectasia fibroblasts to ionizing radiation is associated with a repair deficiency of DNA double-strand breaks. Int. J. Radiat. Biol. 72 (1997) 271-283
    • (1997) Int. J. Radiat. Biol. , vol.72 , pp. 271-283
    • Foray, N.1    Priestley, A.2    Alsbeih, G.3    Badie, C.4    Capulas III, E.P.5    Malaise, C.E.P.F.6
  • 42
    • 0019784701 scopus 로고
    • Evidence for DNA double strand breaks as the critical lesions in yeast cells irradiated with sparsely or densely ionizing radiations under oxic and anoxic conditions
    • Frankenberg D., Frankenberg-Schwager M., Blocher D., and Harbich R. Evidence for DNA double strand breaks as the critical lesions in yeast cells irradiated with sparsely or densely ionizing radiations under oxic and anoxic conditions. Radiat. Res. 88 (1981) 524-532
    • (1981) Radiat. Res. , vol.88 , pp. 524-532
    • Frankenberg, D.1    Frankenberg-Schwager, M.2    Blocher, D.3    Harbich, R.4
  • 44
    • 0027476890 scopus 로고
    • Repair and misrepair of site-specific DNA double-strand breaks by human cell extracts
    • Ganesh A., North P., and Thacker J. Repair and misrepair of site-specific DNA double-strand breaks by human cell extracts. Mutat. Res. 299 (1993) 251-259
    • (1993) Mutat. Res. , vol.299 , pp. 251-259
    • Ganesh, A.1    North, P.2    Thacker, J.3
  • 45
    • 0030966099 scopus 로고    scopus 로고
    • Recent advances in understanding V(D)J recombination
    • Gellert M. Recent advances in understanding V(D)J recombination. Adv. Immunol. 64 (1997) 39-64
    • (1997) Adv. Immunol. , vol.64 , pp. 39-64
    • Gellert, M.1
  • 47
    • 0027397867 scopus 로고
    • The DNA-dependent protein kinase: Requirement of DNA ends and association with Ku Antigen
    • Gottlieb T.M., and Jackson S.P. The DNA-dependent protein kinase: Requirement of DNA ends and association with Ku Antigen. Cell 72 (1993) 131-142
    • (1993) Cell , vol.72 , pp. 131-142
    • Gottlieb, T.M.1    Jackson, S.P.2
  • 48
    • 0030743386 scopus 로고    scopus 로고
    • Activity of DNA ligase IV stimulated by complex formation with XRCC4 protein in mammalian cells
    • Grawunder U., Wilm M., Wu X., Kulesza P., Wilson T.E., Mann M., and Lieber M.R. Activity of DNA ligase IV stimulated by complex formation with XRCC4 protein in mammalian cells. Nature 388 (1997) 492-495
    • (1997) Nature , vol.388 , pp. 492-495
    • Grawunder, U.1    Wilm, M.2    Wu, X.3    Kulesza, P.4    Wilson, T.E.5    Mann, M.6    Lieber, M.R.7
  • 50
    • 0026570651 scopus 로고
    • Ku polypeptides synthesized in vitro assemble into complexes withich recognize ends of double-stranded DNA
    • Griffith A.J., Blier III P.R., and Hardin J.A.T. Ku polypeptides synthesized in vitro assemble into complexes withich recognize ends of double-stranded DNA. J. Biol. Chem. 267 (1992) 331-338
    • (1992) J. Biol. Chem. , vol.267 , pp. 331-338
    • Griffith, A.J.1    Blier III, P.R.2    Hardin, J.A.T.3
  • 51
    • 0030858967 scopus 로고    scopus 로고
    • Ku70-deficient ES cells have increased ionizing radiosensitivity, defective DNA end binding activity and inability to support V(D)J recombination
    • Gu Y., Jin S., Gao III Y., and Alt D.F.W.T. Ku70-deficient ES cells have increased ionizing radiosensitivity, defective DNA end binding activity and inability to support V(D)J recombination. Proc. Natl. Acad. Sci. USA 94 (1997) 8076-8081
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 8076-8081
    • Gu, Y.1    Jin, S.2    Gao III, Y.3    Alt, D.F.W.T.4
  • 53
    • 0023117774 scopus 로고
    • Gene recombination in X-ray sensitive hamster cells
    • Hamilton A.A., and Thacker J. Gene recombination in X-ray sensitive hamster cells. Mol. Cell. Biol. 7 (1987) 1409-1414
    • (1987) Mol. Cell. Biol. , vol.7 , pp. 1409-1414
    • Hamilton, A.A.1    Thacker, J.2
  • 54
    • 0029089618 scopus 로고
    • The mei 41 gene of D. melanogaster is a structural and functional homolog of the human ataxia telangiectasia gene
    • Hari K.L., Santerre A., Sekelsky J.J., McKim K.S., Boyd J.B., and Hawley R.S. The mei 41 gene of D. melanogaster is a structural and functional homolog of the human ataxia telangiectasia gene. Cell 82 (1995) 815-821
    • (1995) Cell , vol.82 , pp. 815-821
    • Hari, K.L.1    Santerre, A.2    Sekelsky, J.J.3    McKim, K.S.4    Boyd, J.B.5    Hawley, R.S.6
  • 57
    • 0023659483 scopus 로고
    • Extrachromosomal DNA substrates in pre-B cells undergo inversion or deletion at immunoglobulin V-(D)-J joining signals
    • Hesse J.E., Lieber M.R., Gellert M., and Mizuuchi K. Extrachromosomal DNA substrates in pre-B cells undergo inversion or deletion at immunoglobulin V-(D)-J joining signals. Cell 49 (1987) 775-783
    • (1987) Cell , vol.49 , pp. 775-783
    • Hesse, J.E.1    Lieber, M.R.2    Gellert, M.3    Mizuuchi, K.4
  • 58
    • 0028856331 scopus 로고
    • When is a lipid kinase not a lipid kinase? When it is a protein kinase
    • Hunter T. When is a lipid kinase not a lipid kinase? When it is a protein kinase. Cell 83 (1995) 1-4
    • (1995) Cell , vol.83 , pp. 1-4
    • Hunter, T.1
  • 59
    • 0025284768 scopus 로고
    • Radiosensitivity throughout the cell cycle and repair of potentially lethal damage and DNA double-strand breaks in an X-ray-sensitive CHO mutant
    • Iliakis G., and Okayasu R. Radiosensitivity throughout the cell cycle and repair of potentially lethal damage and DNA double-strand breaks in an X-ray-sensitive CHO mutant. Int. J. Radiat. Biol. 57 (1990) 1195-1211
    • (1990) Int. J. Radiat. Biol. , vol.57 , pp. 1195-1211
    • Iliakis, G.1    Okayasu, R.2
  • 60
    • 0021923379 scopus 로고
    • X-ray sensitive mutants of Chinese hamster ovary cell line: Radiosensitivity of DNA synthesis
    • Jeggo P.A. X-ray sensitive mutants of Chinese hamster ovary cell line: Radiosensitivity of DNA synthesis. Mutat. Res. 145 (1985) 171-176
    • (1985) Mutat. Res. , vol.145 , pp. 171-176
    • Jeggo, P.A.1
  • 61
    • 0025368957 scopus 로고
    • Studies on mammalian mutants defective in rejoining double-strand breaks in DNA
    • Jeggo P.A. Studies on mammalian mutants defective in rejoining double-strand breaks in DNA. Mutat. Res. 239 (1990) 1-16
    • (1990) Mutat. Res. , vol.239 , pp. 1-16
    • Jeggo, P.A.1
  • 62
    • 0030922250 scopus 로고    scopus 로고
    • DNA-PK: At the cross-roads of biochemistry and genetics
    • Jeggo P.A. DNA-PK: At the cross-roads of biochemistry and genetics. Mutat. Res. 384 (1997) 1-14
    • (1997) Mutat. Res. , vol.384 , pp. 1-14
    • Jeggo, P.A.1
  • 64
    • 0024441217 scopus 로고
    • Decreased stable transfection frequences of six X-ray-sensitive CHO strains, all members of the xrs complementation group
    • Jeggo P.A., and Smith-Ravin J. Decreased stable transfection frequences of six X-ray-sensitive CHO strains, all members of the xrs complementation group. Mutat. Res. 218 (1989) 75-86
    • (1989) Mutat. Res. , vol.218 , pp. 75-86
    • Jeggo, P.A.1    Smith-Ravin, J.2
  • 65
    • 0025971104 scopus 로고
    • Genetic analysis of ionising radiation sensitive mutants of cultured mammalian cell lines
    • Jeggo P.A., Tesmer J., and Chen D.J. Genetic analysis of ionising radiation sensitive mutants of cultured mammalian cell lines. Mutat. Res. 254 (1991) 125-133
    • (1991) Mutat. Res. , vol.254 , pp. 125-133
    • Jeggo, P.A.1    Tesmer, J.2    Chen, D.J.3
  • 66
    • 0028914077 scopus 로고
    • Interaction of Mrel 1 and Rad50: Two proteins required for DNA repair and meiosis-specific double-strand break formation in Saccharomyces cerevisiae
    • Johzuka K., and Ogawa H. Interaction of Mrel 1 and Rad50: Two proteins required for DNA repair and meiosis-specific double-strand break formation in Saccharomyces cerevisiae. Genetics 139 (1995) 1521-1532
    • (1995) Genetics , vol.139 , pp. 1521-1532
    • Johzuka, K.1    Ogawa, H.2
  • 69
    • 0030893115 scopus 로고    scopus 로고
    • Meiosis-specific DNA double-strand breaks are catalyzed by Spol 1, a member of a widely conserved protein family
    • Keeney S., and Giroux C.N. Meiosis-specific DNA double-strand breaks are catalyzed by Spol 1, a member of a widely conserved protein family. Cell 88 (1997) 375-384
    • (1997) Cell , vol.88 , pp. 375-384
    • Keeney, S.1    Giroux, C.N.2
  • 70
    • 0028800996 scopus 로고
    • PIK-related kinases: DNA repair, recombination and cell cycle checkpoints
    • Keith C., and Schreiber S.L.T. PIK-related kinases: DNA repair, recombination and cell cycle checkpoints. Science 270 (1995) 50-51
    • (1995) Science , vol.270 , pp. 50-51
    • Keith, C.1    Schreiber, S.L.T.2
  • 73
    • 0028048275 scopus 로고
    • The mechanism of V(D)J joining: Lessons from molecular, immunological and comparative analyses
    • Lewis S.M. The mechanism of V(D)J joining: Lessons from molecular, immunological and comparative analyses. Adv. Immunol. 56 (1994) 27-150
    • (1994) Adv. Immunol. , vol.56 , pp. 27-150
    • Lewis, S.M.1
  • 74
    • 0029585872 scopus 로고
    • The XRCC4 gene encodes a novel protein involved in DNA double-strand break repair and V(D)J recombination
    • Li Z., Otevrel T., Gao Y., Cheng H.-L., Seed B., Stamato T.D., Taccioli G.E., and Alt F.W. The XRCC4 gene encodes a novel protein involved in DNA double-strand break repair and V(D)J recombination. Cell 83 (1995) 1079-1089
    • (1995) Cell , vol.83 , pp. 1079-1089
    • Li, Z.1    Otevrel, T.2    Gao, Y.3    Cheng, H.-L.4    Seed, B.5    Stamato, T.D.6    Taccioli, G.E.7    Alt, F.W.8
  • 75
    • 15844385545 scopus 로고    scopus 로고
    • Ku80-deficient cells exhibit excess degradation of extrachromosomal DNA
    • Liang F Jasin M. Ku80-deficient cells exhibit excess degradation of extrachromosomal DNA. J. Biol. Chem. 271 (1996) 14405-14411
    • (1996) J. Biol. Chem. , vol.271 , pp. 14405-14411
    • Liang F Jasin, M.1
  • 77
    • 0021123453 scopus 로고
    • Model for homologous recombination during transfer of DNA into mouse L cells: role for DNA ends in the recombination process
    • Lin F.-L., Sperle K., and Sternberg N. Model for homologous recombination during transfer of DNA into mouse L cells: role for DNA ends in the recombination process. Mol. Cell. Biol. 4 (1984) 1020-1034
    • (1984) Mol. Cell. Biol. , vol.4 , pp. 1020-1034
    • Lin, F.-L.1    Sperle, K.2    Sternberg, N.3
  • 78
    • 0025176986 scopus 로고
    • Intermolecular recombination between DNAs introduced into mouse L cells is mediated by a non-conservative pathway that leads to crossover products
    • Lin F.-L., Sperle K., and Sternberg N. Intermolecular recombination between DNAs introduced into mouse L cells is mediated by a non-conservative pathway that leads to crossover products. Mol. Cell. Biol. 10 (1990) 103-112
    • (1990) Mol. Cell. Biol. , vol.10 , pp. 103-112
    • Lin, F.-L.1    Sperle, K.2    Sternberg, N.3
  • 79
    • 0025058136 scopus 로고
    • Repair of double stranded DNA breaks by homologous DNA fragments during transfer o F DNA into mouse L cells
    • Lin F.-L., Sperle K., and Sternberg N. Repair of double stranded DNA breaks by homologous DNA fragments during transfer o F DNA into mouse L cells. Mol. Cell. Biol. 10 (1990) 113-119
    • (1990) Mol. Cell. Biol. , vol.10 , pp. 113-119
    • Lin, F.-L.1    Sperle, K.2    Sternberg, N.3
  • 80
    • 0024986341 scopus 로고
    • The RAD50 gene, a member of the double strand break repair epistasis group, is not required for spontaneous mitotic recombination in yeast
    • Malone R.E., Ward T., Lin S., and Waring J. The RAD50 gene, a member of the double strand break repair epistasis group, is not required for spontaneous mitotic recombination in yeast. Curr. Genet. 18 (1990) 111-116
    • (1990) Curr. Genet. , vol.18 , pp. 111-116
    • Malone, R.E.1    Ward, T.2    Lin, S.3    Waring, J.4
  • 81
    • 0029954821 scopus 로고    scopus 로고
    • Mutations in two Ku homologs define a DNA end-joining repair pathway in Saccharomyces cerevisiae
    • Milne G.T., Jin S., Shannon K.B., and Weaver D.T. Mutations in two Ku homologs define a DNA end-joining repair pathway in Saccharomyces cerevisiae. Mol. Cell. Biol. 16 (1996) 4189-4198
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 4189-4198
    • Milne, G.T.1    Jin, S.2    Shannon, K.B.3    Weaver, D.T.4
  • 82
    • 0019374013 scopus 로고
    • Characterization of a high molecular weight acidic nuclear protein recognized by autoantibodies in sera from patients with polymyositis-scleroderma overlap syndrome
    • Mimori T., Akizuki M., Yamagata H., Inatla S., Yoshida S., and Homma M. Characterization of a high molecular weight acidic nuclear protein recognized by autoantibodies in sera from patients with polymyositis-scleroderma overlap syndrome. J. Clin, Invest 68 (1981) 611-620
    • (1981) J. Clin, Invest , vol.68 , pp. 611-620
    • Mimori, T.1    Akizuki, M.2    Yamagata, H.3    Inatla, S.4    Yoshida, S.5    Homma, M.6
  • 83
    • 0029813249 scopus 로고    scopus 로고
    • The V(D)J recombination defect in the xrs-6 cell line results from a point mutation in the Ku80 gene
    • Mizuta R., Taccioli G.E., and Alt F.W. The V(D)J recombination defect in the xrs-6 cell line results from a point mutation in the Ku80 gene. Int. Immunol. 8 (1996) 1467-1471
    • (1996) Int. Immunol. , vol.8 , pp. 1467-1471
    • Mizuta, R.1    Taccioli, G.E.2    Alt, F.W.3
  • 84
    • 0029976325 scopus 로고    scopus 로고
    • Cell cycle and genetic requirements of two pathways of nonhomologous end-joining repair of double-strand breaks in Saccharomyces cerevisiae
    • Moore J.K., and Haber J.E. Cell cycle and genetic requirements of two pathways of nonhomologous end-joining repair of double-strand breaks in Saccharomyces cerevisiae. Mol. Cell. Biol. 16 (1996) 2164-2173
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 2164-2173
    • Moore, J.K.1    Haber, J.E.2
  • 86
    • 0028286463 scopus 로고
    • DNA-dependent protein kinase is activated by nicks and larger single-stranded gaps
    • Morozov V.E., Falzon III M., and Kuff C.E.L.W. DNA-dependent protein kinase is activated by nicks and larger single-stranded gaps. J. Biol. Chem. 269 (1994) 16684-16688
    • (1994) J. Biol. Chem. , vol.269 , pp. 16684-16688
    • Morozov, V.E.1    Falzon III, M.2    Kuff, C.E.L.W.3
  • 87
    • 0027404612 scopus 로고
    • Formation of large deletions by illegitimate recombination in the HPRTgene of primary human fibroblasts
    • Morris T Thacker J. Formation of large deletions by illegitimate recombination in the HPRTgene of primary human fibroblasts. Proc. Natl. Acad. Sci. USA 90 (1993) 1392-1396
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 1392-1396
    • Morris T Thacker, J.1
  • 89
    • 0030925492 scopus 로고    scopus 로고
    • A novel leucine zipper protein expressed from the Ku86 autoantigen locus is implicated in the control of DNA-dependent protein kinase activity
    • Myung K., He D.M., Lee S.E., and Hendrickson E.A. A novel leucine zipper protein expressed from the Ku86 autoantigen locus is implicated in the control of DNA-dependent protein kinase activity. EMBO J. 16 (1997) 3172-3184
    • (1997) EMBO J. , vol.16 , pp. 3172-3184
    • Myung, K.1    He, D.M.2    Lee, S.E.3    Hendrickson, E.A.4
  • 90
    • 0029971123 scopus 로고    scopus 로고
    • Lack of detectable defect in DNA double-strand break repair and DNA-dependent protein kinase activity in radiosensitivity human severe combined immunodeficiency fibroblasts
    • Nicolas N., Finnie N.J., Cavazzana-Calvo M., Papadopoulo III D., Deist F., Fischer A., Jackson S.P., and de Villartay J.-P. Lack of detectable defect in DNA double-strand break repair and DNA-dependent protein kinase activity in radiosensitivity human severe combined immunodeficiency fibroblasts. Eur. J. Immunol. 26 (1996) 1118-1122
    • (1996) Eur. J. Immunol. , vol.26 , pp. 1118-1122
    • Nicolas, N.1    Finnie, N.J.2    Cavazzana-Calvo, M.3    Papadopoulo III, D.4    Deist, F.5    Fischer, A.6    Jackson, S.P.7    de Villartay, J.-P.8
  • 92
    • 0028147898 scopus 로고
    • Production and characterisation of recombinant human Ku antigen
    • Ono M.P., Tucker P.W., and Capra J.D. Production and characterisation of recombinant human Ku antigen. Nucleic Acids Res. 22 (1994) 3918-3924
    • (1994) Nucleic Acids Res. , vol.22 , pp. 3918-3924
    • Ono, M.P.1    Tucker, P.W.2    Capra, J.D.3
  • 94
    • 0026030088 scopus 로고
    • A unique pathway of double-strand break repair operates in tandemly repeated genes
    • Ozenberger B.A., and Roeder G.S. A unique pathway of double-strand break repair operates in tandemly repeated genes. Mol. Cell. Biol. 11 (1991) 1222-1231
    • (1991) Mol. Cell. Biol. , vol.11 , pp. 1222-1231
    • Ozenberger, B.A.1    Roeder, G.S.2
  • 95
    • 0027245559 scopus 로고
    • V(D)J recombination in mammalian cell mutants defective in DNA double strand break repair
    • Pergola F., Zdzienicka M.Z., and Lieber M.R. V(D)J recombination in mammalian cell mutants defective in DNA double strand break repair. Mol. Cell. Biol. 13 (1993) 3464-3471
    • (1993) Mol. Cell. Biol. , vol.13 , pp. 3464-3471
    • Pergola, F.1    Zdzienicka, M.Z.2    Lieber, M.R.3
  • 96
    • 0028902932 scopus 로고
    • Loss of the catalytic subunit of the DNA-dependent protein kinase in DNA double-strand-break-repair mutant mammalian cells
    • Peterson S.R., Kurimasa A., Oshimura M., Dynan W.S., Bradbury E.M., and Chen D.J. Loss of the catalytic subunit of the DNA-dependent protein kinase in DNA double-strand-break-repair mutant mammalian cells. Proc. Natl. Acad. Sci. USA 92 (1995) 3171-3174
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 3171-3174
    • Peterson, S.R.1    Kurimasa, A.2    Oshimura, M.3    Dynan, W.S.4    Bradbury, E.M.5    Chen, D.J.6
  • 97
    • 0028078579 scopus 로고
    • Mechanisms of overlap formation in nonhomologous DNA end joining
    • Pfeiffer P., Thode S., Hancke J., and Vielmetter W. Mechanisms of overlap formation in nonhomologous DNA end joining. Mol. Cell. Biol. 14 (1994) 888-895
    • (1994) Mol. Cell. Biol. , vol.14 , pp. 888-895
    • Pfeiffer, P.1    Thode, S.2    Hancke, J.3    Vielmetter, W.4
  • 98
    • 0029919650 scopus 로고    scopus 로고
    • The DNA-binding protein Hdflp (a putative Ku homologue) is required for maintaining normal telomere length in Saccha-romyces cerevisiae
    • Porter S.E., Greenwell P.W., Ritchie K.B., and Petes T.D. The DNA-binding protein Hdflp (a putative Ku homologue) is required for maintaining normal telomere length in Saccha-romyces cerevisiae. Nucleic Acids Res. 24 (1996) 582-585
    • (1996) Nucleic Acids Res. , vol.24 , pp. 582-585
    • Porter, S.E.1    Greenwell, P.W.2    Ritchie, K.B.3    Petes, T.D.4
  • 99
    • 0028342645 scopus 로고
    • A DNA end-binding factor involved in double-strand break repair and V(D)J recombination
    • Rathmell W.K., and Chu G. A DNA end-binding factor involved in double-strand break repair and V(D)J recombination. Mol. Cell. Biol. 14 (1994) 4741-4748
    • (1994) Mol. Cell. Biol. , vol.14 , pp. 4741-4748
    • Rathmell, W.K.1    Chu, G.2
  • 100
    • 0031025079 scopus 로고    scopus 로고
    • DNA-dependent protein kinase is not required for accumulation of p53 or cell cycle arrest after DNA damage
    • Rathmell W.K., Kaufmann W.K., Hurt J.C., Byrd L., and Chu G.L. DNA-dependent protein kinase is not required for accumulation of p53 or cell cycle arrest after DNA damage. Cancer Res. 57 (1997) 68-74
    • (1997) Cancer Res. , vol.57 , pp. 68-74
    • Rathmell, W.K.1    Kaufmann, W.K.2    Hurt, J.C.3    Byrd, L.4    Chu, G.L.5
  • 101
    • 0024524581 scopus 로고
    • Molecular cloning of c DNA encoding the p70 (Ku) lupus autoantigen
    • Reeves W.H., and Sthoeger Z.M. Molecular cloning of c DNA encoding the p70 (Ku) lupus autoantigen. J. Biol. Chem. 264 (1989) 5047-5052
    • (1989) J. Biol. Chem. , vol.264 , pp. 5047-5052
    • Reeves, W.H.1    Sthoeger, Z.M.2
  • 102
    • 0017119079 scopus 로고
    • The repair of double strand breaks in DNA: A model involving recombination. J
    • Resnick M.A., and Martin P. The repair of double strand breaks in DNA: A model involving recombination. J. Theoret. Biol. 59 (1976) 97-106
    • (1976) Theoret. Biol. , vol.59 , pp. 97-106
    • Resnick, M.A.1    Martin, P.2
  • 103
    • 0018125129 scopus 로고
    • Separation of linked markers in Chinese hamster cell hybrids: Mitotic recombination is not involved
    • Rosenstauss M.J., and Chasin L.A. Separation of linked markers in Chinese hamster cell hybrids: Mitotic recombination is not involved. Genetics 90 (1978) 735-760
    • (1978) Genetics , vol.90 , pp. 735-760
    • Rosenstauss, M.J.1    Chasin, L.A.2
  • 105
    • 0022256461 scopus 로고
    • Mechanisms of nonhomologous recombination in mammalian cells
    • Roth D.B., Porter T.N., and Wilson J.H. Mechanisms of nonhomologous recombination in mammalian cells. Mol. Cell. Biol. 5 (1985) 2599-2607
    • (1985) Mol. Cell. Biol. , vol.5 , pp. 2599-2607
    • Roth, D.B.1    Porter, T.N.2    Wilson, J.H.3
  • 106
    • 0021827069 scopus 로고
    • Relative rates of homologous and nonhomologous recombination in transfected DNA
    • Roth D.B., and Wilson J.H. Relative rates of homologous and nonhomologous recombination in transfected DNA. Proc. Natl. Acad. Sci. USA 82 (1985) 3355-3359
    • (1985) Proc. Natl. Acad. Sci. USA , vol.82 , pp. 3355-3359
    • Roth, D.B.1    Wilson, J.H.2
  • 107
    • 0022976432 scopus 로고
    • Nonhomologous recombination in mammalian cells: role for short sequence homologies in the joining reaction
    • Roth D.B., and Wilson J.H. Nonhomologous recombination in mammalian cells: role for short sequence homologies in the joining reaction. Mol. Cell. Biol. 6 (1986) 4295-4304
    • (1986) Mol. Cell. Biol. , vol.6 , pp. 4295-4304
    • Roth, D.B.1    Wilson, J.H.2
  • 108
    • 0019172203 scopus 로고
    • Genetic control of diploid recovery after gamma-irradiation in the yeast Saccharomyces cerevisiae
    • Saeki T., Machida I., and Nakai S. Genetic control of diploid recovery after gamma-irradiation in the yeast Saccharomyces cerevisiae. Mutat. Res. 73 (1980) 251-265
    • (1980) Mutat. Res. , vol.73 , pp. 251-265
    • Saeki, T.1    Machida, I.2    Nakai, S.3
  • 110
    • 0030749258 scopus 로고    scopus 로고
    • A newly identified DNA ligase of Saccharomyces cerevisiae involved in RAD52-independent repair of DNA double-strand breaks
    • Schar P., Herrmann G., Daly G., and Lindahl T. A newly identified DNA ligase of Saccharomyces cerevisiae involved in RAD52-independent repair of DNA double-strand breaks. Genes Dev. 11 (1997) 1912-1924
    • (1997) Genes Dev. , vol.11 , pp. 1912-1924
    • Schar, P.1    Herrmann, G.2    Daly, G.3    Lindahl, T.4
  • 111
    • 0028246091 scopus 로고
    • Effect of mutations in genes affecting homologous recombination on restriction enzyme-mediated and illegitimate recombination in Saccharomyces cerevisiae
    • Schiestl R.H., Zhu J., and Petes T.D. Effect of mutations in genes affecting homologous recombination on restriction enzyme-mediated and illegitimate recombination in Saccharomyces cerevisiae. Mol. Cell. Biol. 14 (1994) 4493-4500
    • (1994) Mol. Cell. Biol. , vol.14 , pp. 4493-4500
    • Schiestl, R.H.1    Zhu, J.2    Petes, T.D.3
  • 112
    • 0031569608 scopus 로고    scopus 로고
    • A kinase-negative mutation of DNA-PK(CS) in equine SCID results in defective coding and signal joint formation
    • Shin E.K., Perryman L.E., and Meek K. A kinase-negative mutation of DNA-PK(CS) in equine SCID results in defective coding and signal joint formation. J. Immunol. 158 (1997) 3565-3569
    • (1997) J. Immunol. , vol.158 , pp. 3565-3569
    • Shin, E.K.1    Perryman, L.E.2    Meek, K.3
  • 113
    • 0026751113 scopus 로고
    • RAD51 protein involved in repair and recombination in S. cerevisiae is a Rec A-like protein
    • Shinohara A., Ogawa H., and Ogawa T. RAD51 protein involved in repair and recombination in S. cerevisiae is a Rec A-like protein. Cell 69 (1992) 457-470
    • (1992) Cell , vol.69 , pp. 457-470
    • Shinohara, A.1    Ogawa, H.2    Ogawa, T.3
  • 114
    • 0029822784 scopus 로고    scopus 로고
    • The Saccharomyces cerevisiae MEC1 gene, which encodes a homolog of the human ATM gene product, is required for G1 arrest following radiation treatment
    • Siede W., Allen J.B., Elledge S.J., and Friedberg E.C. The Saccharomyces cerevisiae MEC1 gene, which encodes a homolog of the human ATM gene product, is required for G1 arrest following radiation treatment. J Bacteriol. 178 (1996) 5841-5843
    • (1996) J Bacteriol. , vol.178 , pp. 5841-5843
    • Siede, W.1    Allen, J.B.2    Elledge, S.J.3    Friedberg, E.C.4
  • 115
    • 0030033061 scopus 로고    scopus 로고
    • The Saccha-romyces cerevisiae Ku autoantigen homologue affects radiosensitivity only in the absence of homologous recombination
    • Siede W., Friedl A.A., Dianova-Schupp III I., and Friedberg E.C.F. The Saccha-romyces cerevisiae Ku autoantigen homologue affects radiosensitivity only in the absence of homologous recombination. Genetics 142 (1996) 91-102
    • (1996) Genetics , vol.142 , pp. 91-102
    • Siede, W.1    Friedl, A.A.2    Dianova-Schupp III, I.3    Friedberg, E.C.F.4
  • 118
    • 0028112944 scopus 로고
    • Restoration of X-ray resistance and V(D)J recombination in mutant-cells by Ku c DNA
    • Smider V., Rathmell W.K., Lieber M.R., and Chu G. Restoration of X-ray resistance and V(D)J recombination in mutant-cells by Ku c DNA. Science 266 (1994) 288-291
    • (1994) Science , vol.266 , pp. 288-291
    • Smider, V.1    Rathmell, W.K.2    Lieber, M.R.3    Chu, G.4
  • 119
    • 0024842080 scopus 로고
    • Use of damaged plasmid to study DNA repair in X-ray sensitive (xrs) strians of chinese hamster ovary (CHO) cells
    • Smith-Ravin J., and Jeggo P.A. Use of damaged plasmid to study DNA repair in X-ray sensitive (xrs) strians of chinese hamster ovary (CHO) cells. Int. J. Radiat. Biol. 56 (1989) 951-961
    • (1989) Int. J. Radiat. Biol. , vol.56 , pp. 951-961
    • Smith-Ravin, J.1    Jeggo, P.A.2
  • 120
    • 0031057975 scopus 로고    scopus 로고
    • Cellular radiosensitivity in human severe-combined-immunodeficiency (SCID) syndromes
    • Sproston A.R.M., West C.M., and Hendry J.H.L. Cellular radiosensitivity in human severe-combined-immunodeficiency (SCID) syndromes. Radiother. Oncol. 42 (1997) 53-57
    • (1997) Radiother. Oncol. , vol.42 , pp. 53-57
    • Sproston, A.R.M.1    West, C.M.2    Hendry, J.H.L.3
  • 121
  • 122
    • 0028364447 scopus 로고
    • A DNA repair defect in Chinese hamster ovary cells affects V(D)] recombination similarly to the murine scid mutation
    • Taccioli G.E., Cheng H.-L., Varghese A.J., Whitmore G., and Alt F.W. A DNA repair defect in Chinese hamster ovary cells affects V(D)] recombination similarly to the murine scid mutation. J. Biol. Chem. 269 (1994) 7439-7442
    • (1994) J. Biol. Chem. , vol.269 , pp. 7439-7442
    • Taccioli, G.E.1    Cheng, H.-L.2    Varghese, A.J.3    Whitmore, G.4    Alt, F.W.5
  • 124
    • 0027156278 scopus 로고
    • Impairment of V(D)J recombination in double-strand break repair mutants
    • Taccioli G.E., Rathbun G., Oltz III E., Jeggo T.P.A., and Alt F.W. Impairment of V(D)J recombination in double-strand break repair mutants. Science 260 (1993) 207-210
    • (1993) Science , vol.260 , pp. 207-210
    • Taccioli, G.E.1    Rathbun, G.2    Oltz III, E.3    Jeggo, T.P.A.4    Alt, F.W.5
  • 125
    • 0017695509 scopus 로고
    • A search for allelic recombination in Chinese hamster cell hybrids
    • Tarrant G.M., and Holliday R. A search for allelic recombination in Chinese hamster cell hybrids. Mol. Gen. Genet. 156 (1977) 273-279
    • (1977) Mol. Gen. Genet. , vol.156 , pp. 273-279
    • Tarrant, G.M.1    Holliday, R.2
  • 126
    • 0030051855 scopus 로고    scopus 로고
    • Leukemia and lymphoma in ataxia telangiectasia
    • Taylor A.M.R., Metcalfe J.A., Thick J., and Mak Y.F. Leukemia and lymphoma in ataxia telangiectasia. Blood 87 (1996) 423-438
    • (1996) Blood , vol.87 , pp. 423-438
    • Taylor, A.M.R.1    Metcalfe, J.A.2    Thick, J.3    Mak, Y.F.4
  • 127
    • 0030849085 scopus 로고    scopus 로고
    • Identification of Saccharomyces cerevisiae DNA ligase IV: Involvement in DNA double-strand break repair
    • Teo S.-H., and Jackson S.P. Identification of Saccharomyces cerevisiae DNA ligase IV: Involvement in DNA double-strand break repair. EMBO J. 16 (1997) 4788-4795
    • (1997) EMBO J. , vol.16 , pp. 4788-4795
    • Teo, S.-H.1    Jackson, S.P.2
  • 128
    • 0028593976 scopus 로고
    • Cellular radiosensitivity in ataxia-telangiectasia
    • Thacker J. Cellular radiosensitivity in ataxia-telangiectasia. Int. J. Radiat. Biol. 66 (1994) S87-S96
    • (1994) Int. J. Radiat. Biol. , vol.66
    • Thacker, J.1
  • 130
    • 0021879398 scopus 로고
    • Responses of 4 X-ray-sensitive CHO cell mutants to different radiation and to irrradiation conditions promoting cellular recovery
    • Thacker J., and Stretch A. Responses of 4 X-ray-sensitive CHO cell mutants to different radiation and to irrradiation conditions promoting cellular recovery. Mutat. Res. 146 (1985) 99-108
    • (1985) Mutat. Res. , vol.146 , pp. 99-108
    • Thacker, J.1    Stretch, A.2
  • 131
    • 0026081668 scopus 로고
    • The genetic basis of resistance to ionising radiation damage in cultured mammalian cells
    • Thacker J., and Wilkinson R.E. The genetic basis of resistance to ionising radiation damage in cultured mammalian cells. Mutat. Res. 254 (1991) 135-142
    • (1991) Mutat. Res. , vol.254 , pp. 135-142
    • Thacker, J.1    Wilkinson, R.E.2
  • 132
    • 0025274315 scopus 로고
    • A novel pathway of DNA end-to-end joining
    • Thode S., Schafer A., Pfeiffer P., and Vielmetter W. A novel pathway of DNA end-to-end joining. Cell 60 (1990) 921-928
    • (1990) Cell , vol.60 , pp. 921-928
    • Thode, S.1    Schafer, A.2    Pfeiffer, P.3    Vielmetter, W.4
  • 133
    • 0030580940 scopus 로고    scopus 로고
    • Evidence that mammalian cells possess homologous recombinational repair pathways
    • Thompson L.H. Evidence that mammalian cells possess homologous recombinational repair pathways. Mutat. Res. DNA Rep. 363 (1996) 77-88
    • (1996) Mutat. Res. DNA Rep. , vol.363 , pp. 77-88
    • Thompson, L.H.1
  • 134
    • 0029121551 scopus 로고
    • Nomenclature of human genes involved in ionizing radiation sensitivity
    • Thompson L.H., and Jeggo P.A. Nomenclature of human genes involved in ionizing radiation sensitivity. Mutat. Res. 337 (1995) 131-134
    • (1995) Mutat. Res. , vol.337 , pp. 131-134
    • Thompson, L.H.1    Jeggo, P.A.2
  • 135
    • 0030031522 scopus 로고    scopus 로고
    • Effects of mutations of RAD50, RAD51, RAD52 and related genes on illegitimate recombination in Saccharomyces cerevisiae
    • Tsukamoto Y., Kato J., and Ikeda H. Effects of mutations of RAD50, RAD51, RAD52 and related genes on illegitimate recombination in Saccharomyces cerevisiae. Genetics 142 (1996) 383-391
    • (1996) Genetics , vol.142 , pp. 383-391
    • Tsukamoto, Y.1    Kato, J.2    Ikeda, H.3
  • 136
    • 0030964526 scopus 로고    scopus 로고
    • Silencing factors participate in DNA repair and recombination in Saccharomyces cerevisiae
    • Tsukamoto Y., Kato J., and Ikeda H. Silencing factors participate in DNA repair and recombination in Saccharomyces cerevisiae. Nature 388 (1997) 900-903
    • (1997) Nature , vol.388 , pp. 900-903
    • Tsukamoto, Y.1    Kato, J.2    Ikeda, H.3
  • 137
    • 0029971906 scopus 로고    scopus 로고
    • Hdfl, a yeast Ku-protein homologue, is involved in illegitimate recombination, but not in homologous recombination
    • Tsukamoto Y., Kato J.I., and Ikeda H. Hdfl, a yeast Ku-protein homologue, is involved in illegitimate recombination, but not in homologous recombination. Nucleic Acids Res. 24 (1996) 2067-2072
    • (1996) Nucleic Acids Res. , vol.24 , pp. 2067-2072
    • Tsukamoto, Y.1    Kato, J.I.2    Ikeda, H.3
  • 140
    • 0022534749 scopus 로고
    • Molecular characterization of the human excision repair gene ERCC-1: c DNA cloning and amino acid homology with the yeast DNA repair gene RADIO
    • van Duin M., de Wit J., Odijk H., Westerveld A., Yasui A., Koken M.H.M., Hoijmakers J.H.J., and Bootsma D. Molecular characterization of the human excision repair gene ERCC-1: c DNA cloning and amino acid homology with the yeast DNA repair gene RADIO. Cell 44 (1986) 913-923
    • (1986) Cell , vol.44 , pp. 913-923
    • van Duin, M.1    de Wit, J.2    Odijk, H.3    Westerveld, A.4    Yasui, A.5    Koken, M.H.M.6    Hoijmakers, J.H.J.7    Bootsma, D.8
  • 141
    • 0029967722 scopus 로고    scopus 로고
    • Similarities between initiation of V(D)J recombination and retroviral integration
    • van Gent D., Mizuuchi K., and Gellert M. Similarities between initiation of V(D)J recombination and retroviral integration. Science 271 (1996) 1592-1594
    • (1996) Science , vol.271 , pp. 1592-1594
    • van Gent, D.1    Mizuuchi, K.2    Gellert, M.3
  • 144
    • 0021979299 scopus 로고
    • Double strand break repair and G2 block in Chinese hamster ovary cells and their radiosensitive mutants
    • Weibezahn K.F., Lohrer H., and Herrlich P. Double strand break repair and G2 block in Chinese hamster ovary cells and their radiosensitive mutants. Mutat. Res. 145 (1985) 177-183
    • (1985) Mutat. Res. , vol.145 , pp. 177-183
    • Weibezahn, K.F.1    Lohrer, H.2    Herrlich, P.3
  • 145
    • 0024368474 scopus 로고
    • Cell cycle responses of two X-ray sensitive mutants defective in DNA repair
    • Whitmore G.F., Varghese A.J., and Gulyas S. Cell cycle responses of two X-ray sensitive mutants defective in DNA repair. Int. J. Radiat. Biol. 56 (1989) 657-665
    • (1989) Int. J. Radiat. Biol. , vol.56 , pp. 657-665
    • Whitmore, G.F.1    Varghese, A.J.2    Gulyas, S.3
  • 146
    • 0029582791 scopus 로고
    • Equine severe combined immunodeficiency-A defect in V(D)J recombination and DNA-dependent proteinkinase activity
    • Wiler R., Leber R., Moore III B.B., Perryman L.F.L.E., and Meek K. Equine severe combined immunodeficiency-A defect in V(D)J recombination and DNA-dependent proteinkinase activity. Proc. Natl. Acad. Sci. UAS 92 (1995) 11485-11489
    • (1995) Proc. Natl. Acad. Sci. UAS , vol.92 , pp. 11485-11489
    • Wiler, R.1    Leber, R.2    Moore III, B.B.3    Perryman, L.F.L.E.4    Meek, K.5
  • 147
    • 0030811523 scopus 로고    scopus 로고
    • Yeast DNA ligase IV mediates non-homologous DNA end joining
    • Wilson T.E., Grawunder U., and Lieber M.R. Yeast DNA ligase IV mediates non-homologous DNA end joining. Nature 388 (1997) 495-498
    • (1997) Nature , vol.388 , pp. 495-498
    • Wilson, T.E.1    Grawunder, U.2    Lieber, M.R.3
  • 148
    • 0029740571 scopus 로고    scopus 로고
    • Protein-protein and protein-DNA interaction regions within the DNA end-binding protein Ku70-Ku86
    • Wu X., and Lieber M.R. Protein-protein and protein-DNA interaction regions within the DNA end-binding protein Ku70-Ku86. J. Mol. Cell. Biol. 16 (1996) 5186-5193
    • (1996) J. Mol. Cell. Biol. , vol.16 , pp. 5186-5193
    • Wu, X.1    Lieber, M.R.2
  • 149
    • 0024374896 scopus 로고
    • c DNA-derived amino acid sequence of the 86-k Da subunit of the Ku antigen
    • Yaneva M., Wen J., Ayala A., and Cook R. c DNA-derived amino acid sequence of the 86-k Da subunit of the Ku antigen. J. Biol. Chem. 264 (1989) 13407-13411
    • (1989) J. Biol. Chem. , vol.264 , pp. 13407-13411
    • Yaneva, M.1    Wen, J.2    Ayala, A.3    Cook, R.4
  • 150
    • 0026698728 scopus 로고
    • On the mechanisms of Ku protein binding to DNA
    • Zhang W.-W., and Yaneva M. On the mechanisms of Ku protein binding to DNA. Biochem. Biophys. Res. 186 (1992) 574-579
    • (1992) Biochem. Biophys. Res. , vol.186 , pp. 574-579
    • Zhang, W.-W.1    Yaneva, M.2
  • 151
    • 0030848286 scopus 로고    scopus 로고
    • Identification of a member of a DNA-dependent ATPase family that causes interference with silencing
    • Zhang Z., and Buchman A.R. Identification of a member of a DNA-dependent ATPase family that causes interference with silencing. Mol. Cell. Biol. 17 (1997) 5461-5472
    • (1997) Mol. Cell. Biol. , vol.17 , pp. 5461-5472
    • Zhang, Z.1    Buchman, A.R.2
  • 152
    • 0030576534 scopus 로고    scopus 로고
    • Ku86-deficient mice exhibit severe combined immunodeficiency and defective processing of V(D)J recombination intermediates
    • Zhu C.M., Bogue M.A., Lim D.S., Hasty P., and Roth D.B. Ku86-deficient mice exhibit severe combined immunodeficiency and defective processing of V(D)J recombination intermediates. Cell 86 (1996) 379-389
    • (1996) Cell , vol.86 , pp. 379-389
    • Zhu, C.M.1    Bogue, M.A.2    Lim, D.S.3    Hasty, P.4    Roth, D.B.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.