To nick or not to nick: Comparison of I-SceI single- And double-strand break-induced recombination in yeast and human cells

PLoS ONE

Volumn 9, Issue 2, 2014, Pages

  Katz, Samantha S ^a   Gimble, Frederick S ^b   Storici, Francesca ^a  

^a GEORGIA INSTITUTE OF TECHNOLOGY   (United States)

^b PURDUE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; ENDONUCLEASE; I SCEL ENDONUCLEASE; I SCEL NICKASE; UNCLASSIFIED DRUG; DEOXYRIBONUCLEASE I; RAD51 PROTEIN;

ARTICLE; BIOTECHNOLOGY; CELL STIMULATION; CELL STRAIN HEK293; CONTROLLED STUDY; DOUBLE STRANDED DNA BREAK; ENZYME ACTIVITY; G1 PHASE CELL CYCLE CHECKPOINT; GENE TARGETING; GENE THERAPY; GENETIC RECOMBINATION; GENETIC VARIABILITY; HUMAN; HUMAN CELL; MOLECULAR BIOLOGY; NONHUMAN; SACCHAROMYCES CEREVISIAE; SINGLE STRANDED DNA BREAK; TARGETED GENE REPAIR; WILD TYPE; YEAST CELL; COMPARATIVE STUDY; CYTOLOGY; DNA CLEAVAGE; GENE LOCUS; GENETICS; HEK293 CELL LINE; HOMOLOGOUS RECOMBINATION; METABOLISM; MUTATION; NUCLEOTIDE SEQUENCE; PROCEDURES;

BASE SEQUENCE; DEOXYRIBONUCLEASE I; DNA BREAKS, DOUBLE-STRANDED; DNA BREAKS, SINGLE-STRANDED; DNA CLEAVAGE; G1 PHASE CELL CYCLE CHECKPOINTS; GENE TARGETING; GENETIC LOCI; HEK293 CELLS; HOMOLOGOUS RECOMBINATION; HUMANS; MUTATION; RAD51 RECOMBINASE; SACCHAROMYCES CEREVISIAE;

EID: 84895897031     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0088840     Document Type: Article

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