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Volumn 30, Issue , 2017, Pages 12-27

Murine models for mucosal tolerance in allergy

Author keywords

Allergy; Animal models; BALT; Commensals; GALT; Mucosal tolerance; NALT; Regulatory T cells

Indexed keywords

AEROALLERGEN; ALLERGEN; BACTERIAL TOXIN; CHITIN; CHITOSAN; CHOLERA TOXIN B SUBUNIT; CPG OLIGODEOXYNUCLEOTIDE; LYMPHOTOXIN; PROBIOTIC AGENT; RECOMBINANT ALLERGEN; UNCLASSIFIED DRUG;

EID: 85028332947     PISSN: 10445323     EISSN: 10963618     Source Type: Journal    
DOI: 10.1016/j.smim.2017.07.007     Document Type: Review
Times cited : (12)

References (278)
  • 1
    • 84892454635 scopus 로고    scopus 로고
    • Immunity at the barriers
    • Belkaid, Y., Artis, D., Immunity at the barriers. Eur. J. Immunol. 43:12 (2013), 3096–3097.
    • (2013) Eur. J. Immunol. , vol.43 , Issue.12 , pp. 3096-3097
    • Belkaid, Y.1    Artis, D.2
  • 2
    • 84877299772 scopus 로고    scopus 로고
    • Mucosal immunology of food allergy
    • Berin, M.C., Sampson, H.A., Mucosal immunology of food allergy. Curr. Biol. 23:9 (2013), R389–400.
    • (2013) Curr. Biol. , vol.23 , Issue.9 , pp. R389-400
    • Berin, M.C.1    Sampson, H.A.2
  • 3
    • 84937690389 scopus 로고    scopus 로고
    • Barrier epithelial cells and the control of type 2 immunity
    • Hammad, H., Lambrecht, B.N., Barrier epithelial cells and the control of type 2 immunity. Immunity 43:1 (2015), 29–40.
    • (2015) Immunity , vol.43 , Issue.1 , pp. 29-40
    • Hammad, H.1    Lambrecht, B.N.2
  • 4
    • 33646175590 scopus 로고    scopus 로고
    • Intestinal and pulmonary mucosal T cells: local heroes fight to maintain the status quo
    • Lefrancois, L., Puddington, L., Intestinal and pulmonary mucosal T cells: local heroes fight to maintain the status quo. Annu. Rev. Immunol. 24 (2006), 681–704.
    • (2006) Annu. Rev. Immunol. , vol.24 , pp. 681-704
    • Lefrancois, L.1    Puddington, L.2
  • 5
    • 84908631984 scopus 로고    scopus 로고
    • Mechanisms of immune tolerance to allergens: role of IL-10 and Tregs
    • Akdis, C.A., Akdis, M., Mechanisms of immune tolerance to allergens: role of IL-10 and Tregs. J. Clin. Invest. 124:11 (2014), 4678–4680.
    • (2014) J. Clin. Invest. , vol.124 , Issue.11 , pp. 4678-4680
    • Akdis, C.A.1    Akdis, M.2
  • 6
    • 84947983135 scopus 로고    scopus 로고
    • Mechanisms underlying induction of tolerance to foods
    • Berin, M.C., Shreffler, W.G., Mechanisms underlying induction of tolerance to foods. Immunol. Allergy Clin. North. Am. 36:1 (2016), 87–102.
    • (2016) Immunol. Allergy Clin. North. Am. , vol.36 , Issue.1 , pp. 87-102
    • Berin, M.C.1    Shreffler, W.G.2
  • 8
    • 84906841721 scopus 로고    scopus 로고
    • Allergens and the airway epithelium response: gateway to allergic sensitization
    • Lambrecht, B.N., Hammad, H., Allergens and the airway epithelium response: gateway to allergic sensitization. J. Allergy Clin. Immunol. 134:3 (2014), 499–507.
    • (2014) J. Allergy Clin. Immunol. , vol.134 , Issue.3 , pp. 499-507
    • Lambrecht, B.N.1    Hammad, H.2
  • 11
    • 84866130874 scopus 로고    scopus 로고
    • Interleukin-1alpha controls allergic sensitization to inhaled house dust mite via the epithelial release of GM-CSF and IL-33
    • Willart, M.A., Deswarte, K., Pouliot, P., Braun, H., Beyaert, R., Lambrecht, B.N., Hammad, H., Interleukin-1alpha controls allergic sensitization to inhaled house dust mite via the epithelial release of GM-CSF and IL-33. J. Exp. Med. 209:8 (2012), 1505–1517.
    • (2012) J. Exp. Med. , vol.209 , Issue.8 , pp. 1505-1517
    • Willart, M.A.1    Deswarte, K.2    Pouliot, P.3    Braun, H.4    Beyaert, R.5    Lambrecht, B.N.6    Hammad, H.7
  • 12
    • 68549115370 scopus 로고    scopus 로고
    • Immunotherapy in the treatment of food allergy: focus on oral tolerance
    • Vickery, B.P., Burks, A.W., Immunotherapy in the treatment of food allergy: focus on oral tolerance. Curr. Opin. Allergy Clin. Immunol. 9:4 (2009), 364–370.
    • (2009) Curr. Opin. Allergy Clin. Immunol. , vol.9 , Issue.4 , pp. 364-370
    • Vickery, B.P.1    Burks, A.W.2
  • 13
    • 0002428852 scopus 로고
    • Remarks on a cutaneous affection, produced by certain poisonous vegetables
    • Dakin, R., Remarks on a cutaneous affection, produced by certain poisonous vegetables. Am. J. Med. Sci. 4 (1829), 98–100.
    • (1829) Am. J. Med. Sci. , vol.4 , pp. 98-100
    • Dakin, R.1
  • 14
    • 84951657129 scopus 로고
    • Studies on the chemistry of anaphylaxis (III). Experiments with isolated proteins, especially those of the hen's egg
    • Wells, H.G., Studies on the chemistry of anaphylaxis (III). Experiments with isolated proteins, especially those of the hen's egg. J. Infect. Dis. 9:2 (1911), 147–171.
    • (1911) J. Infect. Dis. , vol.9 , Issue.2 , pp. 147-171
    • Wells, H.G.1
  • 15
    • 84960586762 scopus 로고
    • The biological reactions of the vegetable proteins. I. Anaphylaxis
    • Wells, H.G., Osborne, T.B., The biological reactions of the vegetable proteins. I. Anaphylaxis. J. Infect Dis. 8:1 (1911), 66–124.
    • (1911) J. Infect Dis. , vol.8 , Issue.1 , pp. 66-124
    • Wells, H.G.1    Osborne, T.B.2
  • 16
    • 0019311674 scopus 로고
    • Mucosal immunology
    • Bienenstock, J., Befus, A.D., Mucosal immunology. Immunology 41:2 (1980), 249–270.
    • (1980) Immunology , vol.41 , Issue.2 , pp. 249-270
    • Bienenstock, J.1    Befus, A.D.2
  • 17
    • 0018745032 scopus 로고
    • Evidence for a common mucosal immunologic system. I. Migration of B immunoblasts into intestinal, respiratory, and genital tissues
    • McDermott, M.R., Bienenstock, J., Evidence for a common mucosal immunologic system. I. Migration of B immunoblasts into intestinal, respiratory, and genital tissues. J. Immunol. 122:5 (1979), 1892–1898.
    • (1979) J. Immunol. , vol.122 , Issue.5 , pp. 1892-1898
    • McDermott, M.R.1    Bienenstock, J.2
  • 18
    • 84859808080 scopus 로고    scopus 로고
    • Oral tolerance to food protein
    • Pabst, O., Mowat, A.M., Oral tolerance to food protein. Mucosal Immunol. 5:3 (2012), 232–239.
    • (2012) Mucosal Immunol. , vol.5 , Issue.3 , pp. 232-239
    • Pabst, O.1    Mowat, A.M.2
  • 20
    • 84961635283 scopus 로고    scopus 로고
    • Lung-gut cross-talk: evidence, mechanisms and implications for the mucosal inflammatory diseases
    • Tulic, M.K., Piche, T., Verhasselt, V., Lung-gut cross-talk: evidence, mechanisms and implications for the mucosal inflammatory diseases. Clin. Exp. Allergy 46:4 (2016), 519–528.
    • (2016) Clin. Exp. Allergy , vol.46 , Issue.4 , pp. 519-528
    • Tulic, M.K.1    Piche, T.2    Verhasselt, V.3
  • 21
    • 46749126890 scopus 로고    scopus 로고
    • Adaptive Foxp3+ regulatory T cell-dependent and -independent control of allergic inflammation
    • Curotto de Lafaille, M.A., Kutchukhidze, N., Shen, S., Ding, Y., Yee, H., Lafaille, J.J., Adaptive Foxp3+ regulatory T cell-dependent and -independent control of allergic inflammation. Immunity 29:1 (2008), 114–126.
    • (2008) Immunity , vol.29 , Issue.1 , pp. 114-126
    • Curotto de Lafaille, M.A.1    Kutchukhidze, N.2    Shen, S.3    Ding, Y.4    Yee, H.5    Lafaille, J.J.6
  • 22
    • 78049309522 scopus 로고    scopus 로고
    • Mechanisms of tolerance and allergic sensitization in the airways and the lungs
    • Curotto de Lafaille, M.A., Lafaille, J.J., Graca, L., Mechanisms of tolerance and allergic sensitization in the airways and the lungs. Curr. Opin. Immunol. 22:5 (2010), 616–622.
    • (2010) Curr. Opin. Immunol. , vol.22 , Issue.5 , pp. 616-622
    • Curotto de Lafaille, M.A.1    Lafaille, J.J.2    Graca, L.3
  • 24
    • 0037902480 scopus 로고    scopus 로고
    • T cell anergy and costimulation
    • Appleman, L.J., Boussiotis, V.A., T cell anergy and costimulation. Immunol. Rev. 192 (2003), 161–180.
    • (2003) Immunol. Rev. , vol.192 , pp. 161-180
    • Appleman, L.J.1    Boussiotis, V.A.2
  • 25
    • 0029031681 scopus 로고
    • Peripheral deletion of antigen-reactive T cells in oral tolerance
    • Chen, Y., Inobe, J., Marks, R., Gonnella, P., Kuchroo, V.K., Weiner, H.L., Peripheral deletion of antigen-reactive T cells in oral tolerance. Nature 376:6536 (1995), 177–180.
    • (1995) Nature , vol.376 , Issue.6536 , pp. 177-180
    • Chen, Y.1    Inobe, J.2    Marks, R.3    Gonnella, P.4    Kuchroo, V.K.5    Weiner, H.L.6
  • 27
    • 2942620546 scopus 로고    scopus 로고
    • Therapeutic potential of oral tolerance
    • Mayer, L., Shao, L., Therapeutic potential of oral tolerance. Nat. Rev. Immunol. 4:6 (2004), 407–419.
    • (2004) Nat. Rev. Immunol. , vol.4 , Issue.6 , pp. 407-419
    • Mayer, L.1    Shao, L.2
  • 28
    • 0027538442 scopus 로고
    • Direct evidence for anergy in T lymphocytes tolerized by oral administration of ovalbumin
    • Melamed, D., Friedman, A., Direct evidence for anergy in T lymphocytes tolerized by oral administration of ovalbumin. Eur. J. Immunol. 23:4 (1993), 935–942.
    • (1993) Eur. J. Immunol. , vol.23 , Issue.4 , pp. 935-942
    • Melamed, D.1    Friedman, A.2
  • 29
    • 0028358048 scopus 로고
    • Induction of anergy or active suppression following oral tolerance is determined by antigen dosage
    • Friedman, A., Weiner, H.L., Induction of anergy or active suppression following oral tolerance is determined by antigen dosage. Proc. Natl. Acad. Sci. U. S. A. 91:14 (1994), 6688–6692.
    • (1994) Proc. Natl. Acad. Sci. U. S. A. , vol.91 , Issue.14 , pp. 6688-6692
    • Friedman, A.1    Weiner, H.L.2
  • 30
    • 0031105347 scopus 로고    scopus 로고
    • The oral administration of low-dose antigen induces activation followed by tolerization, while high-dose antigen induces tolerance without activation
    • Yoshida, T., Hachimura, S., Kaminogawa, S., The oral administration of low-dose antigen induces activation followed by tolerization, while high-dose antigen induces tolerance without activation. Clin. Immunol. Immunopathol. 82:3 (1997), 207–215.
    • (1997) Clin. Immunol. Immunopathol. , vol.82 , Issue.3 , pp. 207-215
    • Yoshida, T.1    Hachimura, S.2    Kaminogawa, S.3
  • 31
    • 0030043855 scopus 로고    scopus 로고
    • Oral tolerance in myelin basic protein T-cell receptor transgenic mice: suppression of autoimmune encephalomyelitis and dose-dependent induction of regulatory cells
    • Chen, Y., Inobe, J., Kuchroo, V.K., Baron, J.L., Janeway, C.A. Jr., Weiner, H.L., Oral tolerance in myelin basic protein T-cell receptor transgenic mice: suppression of autoimmune encephalomyelitis and dose-dependent induction of regulatory cells. Proc. Natl. Acad. Sci. U. S. A. 93:1 (1996), 388–391.
    • (1996) Proc. Natl. Acad. Sci. U. S. A. , vol.93 , Issue.1 , pp. 388-391
    • Chen, Y.1    Inobe, J.2    Kuchroo, V.K.3    Baron, J.L.4    Janeway, C.A.5    Weiner, H.L.6
  • 32
    • 0022005411 scopus 로고
    • The role of antigen recognition and suppressor cells in mice with oral tolerance to ovalbumin
    • Mowat, A.M., The role of antigen recognition and suppressor cells in mice with oral tolerance to ovalbumin. Immunology 56:2 (1985), 253–260.
    • (1985) Immunology , vol.56 , Issue.2 , pp. 253-260
    • Mowat, A.M.1
  • 33
    • 0022501454 scopus 로고
    • Divergent effects of bacterial lipopolysaccharide on immunity to orally administered protein and particulate antigens in mice
    • Mowat, A.M., Thomas, M.J., MacKenzie, S., Parrott, D.M., Divergent effects of bacterial lipopolysaccharide on immunity to orally administered protein and particulate antigens in mice. Immunology 58:4 (1986), 677–683.
    • (1986) Immunology , vol.58 , Issue.4 , pp. 677-683
    • Mowat, A.M.1    Thomas, M.J.2    MacKenzie, S.3    Parrott, D.M.4
  • 36
    • 84983087330 scopus 로고    scopus 로고
    • Is clinical tolerance possible after allergen immunotherapy?
    • Moran, T.P., Burks, A.W., Is clinical tolerance possible after allergen immunotherapy?. Curr. Allergy Asthma Rep., 15(5), 2015, 23.
    • (2015) Curr. Allergy Asthma Rep. , vol.15 , Issue.5 , pp. 23
    • Moran, T.P.1    Burks, A.W.2
  • 37
    • 84965002935 scopus 로고    scopus 로고
    • How colonization by microbiota in early life shapes the immune system
    • Gensollen, T., Iyer, S.S., Kasper, D.L., Blumberg, R.S., How colonization by microbiota in early life shapes the immune system. Science 352:6285 (2016), 539–544.
    • (2016) Science , vol.352 , Issue.6285 , pp. 539-544
    • Gensollen, T.1    Iyer, S.S.2    Kasper, D.L.3    Blumberg, R.S.4
  • 40
    • 84964394166 scopus 로고    scopus 로고
    • The microbiome, timing, and barrier function in the context of allergic disease
    • Wesemann, D.R., Nagler, C.R., The microbiome, timing, and barrier function in the context of allergic disease. Immunity 44:4 (2016), 728–738.
    • (2016) Immunity , vol.44 , Issue.4 , pp. 728-738
    • Wesemann, D.R.1    Nagler, C.R.2
  • 41
    • 84921786777 scopus 로고    scopus 로고
    • Regional specialization within the intestinal immune system
    • Mowat, A.M., Agace, W.W., Regional specialization within the intestinal immune system. Nat. Rev. Immunol. 14:10 (2014), 667–685.
    • (2014) Nat. Rev. Immunol. , vol.14 , Issue.10 , pp. 667-685
    • Mowat, A.M.1    Agace, W.W.2
  • 42
    • 0030297089 scopus 로고    scopus 로고
    • The indigenous gastrointestinal microflora
    • Berg, R.D., The indigenous gastrointestinal microflora. Trends Microbiol. 4:11 (1996), 430–435.
    • (1996) Trends Microbiol. , vol.4 , Issue.11 , pp. 430-435
    • Berg, R.D.1
  • 43
    • 25444518195 scopus 로고    scopus 로고
    • Cutting edge: bacterial modulation of epithelial signaling via changes in neddylation of cullin-1
    • Collier-Hyams, L.S., Sloane, V., Batten, B.C., Neish, A.S., Cutting edge: bacterial modulation of epithelial signaling via changes in neddylation of cullin-1. J. Immunol. 175:7 (2005), 4194–4198.
    • (2005) J. Immunol. , vol.175 , Issue.7 , pp. 4194-4198
    • Collier-Hyams, L.S.1    Sloane, V.2    Batten, B.C.3    Neish, A.S.4
  • 44
    • 20744453487 scopus 로고    scopus 로고
    • Innate immune relationship between commensal flora and the mammalian intestinal epithelium
    • Collier-Hyams, L.S., Neish, A.S., Innate immune relationship between commensal flora and the mammalian intestinal epithelium. Cell. Mol. Life Sci. 62:12 (2005), 1339–1348.
    • (2005) Cell. Mol. Life Sci. , vol.62 , Issue.12 , pp. 1339-1348
    • Collier-Hyams, L.S.1    Neish, A.S.2
  • 45
    • 84903641902 scopus 로고    scopus 로고
    • Gut commensal flora: tolerance and homeostasis
    • Rescigno, M., Gut commensal flora: tolerance and homeostasis. F1000 Biol. Rep., 1, 2009, 9.
    • (2009) F1000 Biol. Rep. , vol.1 , pp. 9
    • Rescigno, M.1
  • 46
    • 37849032964 scopus 로고    scopus 로고
    • Epithelial cells prime the immune response to an array of gut-derived commensals towards a tolerogenic phenotype through distinct actions of thymic stromal lymphopoietin and transforming growth factor-beta
    • Zeuthen, L.H., Fink, L.N., Frokiaer, H., Epithelial cells prime the immune response to an array of gut-derived commensals towards a tolerogenic phenotype through distinct actions of thymic stromal lymphopoietin and transforming growth factor-beta. Immunology 123:2 (2008), 197–208.
    • (2008) Immunology , vol.123 , Issue.2 , pp. 197-208
    • Zeuthen, L.H.1    Fink, L.N.2    Frokiaer, H.3
  • 49
    • 84977480198 scopus 로고    scopus 로고
    • Microbiome and its impact on gastrointestinal atopy
    • Muir, A.B., Benitez, A.J., Dods, K., Spergel, J.M., Fillon, S.A., Microbiome and its impact on gastrointestinal atopy. Allergy 71:9 (2016), 1256–1263.
    • (2016) Allergy , vol.71 , Issue.9 , pp. 1256-1263
    • Muir, A.B.1    Benitez, A.J.2    Dods, K.3    Spergel, J.M.4    Fillon, S.A.5
  • 50
    • 2442660296 scopus 로고    scopus 로고
    • Toll-like receptor 4 signaling by intestinal microbes influences susceptibility to food allergy
    • Bashir, M.E., Louie, S., Shi, H.N., Nagler-Anderson, C., Toll-like receptor 4 signaling by intestinal microbes influences susceptibility to food allergy. J. Immunol. 172:11 (2004), 6978–6987.
    • (2004) J. Immunol. , vol.172 , Issue.11 , pp. 6978-6987
    • Bashir, M.E.1    Louie, S.2    Shi, H.N.3    Nagler-Anderson, C.4
  • 52
    • 84958910139 scopus 로고    scopus 로고
    • Dietary antigens limit mucosal immunity by inducing regulatory T cells in the small intestine
    • Kim, K.S., Hong, S.W., Han, D., Yi, J., Jung, J., Yang, B.G., Lee, J.Y., Lee, M., Surh, C.D., Dietary antigens limit mucosal immunity by inducing regulatory T cells in the small intestine. Science 351:6275 (2016), 858–863.
    • (2016) Science , vol.351 , Issue.6275 , pp. 858-863
    • Kim, K.S.1    Hong, S.W.2    Han, D.3    Yi, J.4    Jung, J.5    Yang, B.G.6    Lee, J.Y.7    Lee, M.8    Surh, C.D.9
  • 53
    • 84940841484 scopus 로고    scopus 로고
    • Induction of immune tolerance to dietary antigens
    • Kim, K.S., Surh, C.D., Induction of immune tolerance to dietary antigens. Adv. Exp. Med. Biol. 850 (2015), 93–118.
    • (2015) Adv. Exp. Med. Biol. , vol.850 , pp. 93-118
    • Kim, K.S.1    Surh, C.D.2
  • 54
    • 83655210632 scopus 로고    scopus 로고
    • Homeostatic impact of indigenous microbiota and secretory immunity
    • Brandtzaeg, P., Homeostatic impact of indigenous microbiota and secretory immunity. Beneficial Microbes 1:3 (2010), 211–227.
    • (2010) Beneficial Microbes , vol.1 , Issue.3 , pp. 211-227
    • Brandtzaeg, P.1
  • 55
    • 77955013395 scopus 로고    scopus 로고
    • Intestinal commensal bacteria promote T cell hyporesponsiveness and down-regulate the serum antibody responses induced by dietary antigen
    • Tsuda, M., Hosono, A., Yanagibashi, T., Kihara-Fujioka, M., Hachimura, S., Itoh, K., Hirayama, K., Takahashi, K., Kaminogawa, S., Intestinal commensal bacteria promote T cell hyporesponsiveness and down-regulate the serum antibody responses induced by dietary antigen. Immunol. Lett. 132:1–2 (2010), 45–52.
    • (2010) Immunol. Lett. , vol.132 , Issue.1-2 , pp. 45-52
    • Tsuda, M.1    Hosono, A.2    Yanagibashi, T.3    Kihara-Fujioka, M.4    Hachimura, S.5    Itoh, K.6    Hirayama, K.7    Takahashi, K.8    Kaminogawa, S.9
  • 56
    • 40649095873 scopus 로고    scopus 로고
    • Susceptibility to nasal and oral tolerance induction to the major birch pollen allergen Bet v 1 is not dependent on the presence of the microflora
    • Repa, A., Kozakova, H., Hudcovic, T., Stepankova, R., Hrncir, T., Tlaskalova-Hogenova, H., Pollak, A., Wiedermann, U., Susceptibility to nasal and oral tolerance induction to the major birch pollen allergen Bet v 1 is not dependent on the presence of the microflora. Immunol. Lett. 117:1 (2008), 50–56.
    • (2008) Immunol. Lett. , vol.117 , Issue.1 , pp. 50-56
    • Repa, A.1    Kozakova, H.2    Hudcovic, T.3    Stepankova, R.4    Hrncir, T.5    Tlaskalova-Hogenova, H.6    Pollak, A.7    Wiedermann, U.8
  • 59
    • 0027521572 scopus 로고
    • Interleukin-10-deficient mice develop chronic enterocolitis
    • Kuhn, R., Lohler, J., Rennick, D., Rajewsky, K., Muller, W., Interleukin-10-deficient mice develop chronic enterocolitis. Cell 75:2 (1993), 263–274.
    • (1993) Cell , vol.75 , Issue.2 , pp. 263-274
    • Kuhn, R.1    Lohler, J.2    Rennick, D.3    Rajewsky, K.4    Muller, W.5
  • 60
    • 0032412057 scopus 로고    scopus 로고
    • Resident enteric bacteria are necessary for development of spontaneous colitis and immune system activation in interleukin-10-deficient mice
    • Sellon, R.K., Tonkonogy, S., Schultz, M., Dieleman, L.A., Grenther, W., Balish, E., Rennick, D.M., Sartor, R.B., Resident enteric bacteria are necessary for development of spontaneous colitis and immune system activation in interleukin-10-deficient mice. Infect. Immun. 66:11 (1998), 5224–5231.
    • (1998) Infect. Immun. , vol.66 , Issue.11 , pp. 5224-5231
    • Sellon, R.K.1    Tonkonogy, S.2    Schultz, M.3    Dieleman, L.A.4    Grenther, W.5    Balish, E.6    Rennick, D.M.7    Sartor, R.B.8
  • 62
    • 84879336857 scopus 로고    scopus 로고
    • Microfold (M) cells: important immunosurveillance posts in the intestinal epithelium
    • Mabbott, N.A., Donaldson, D.S., Ohno, H., Williams, I.R., Mahajan, A., Microfold (M) cells: important immunosurveillance posts in the intestinal epithelium. Mucosal Immunol. 6:4 (2013), 666–677.
    • (2013) Mucosal Immunol. , vol.6 , Issue.4 , pp. 666-677
    • Mabbott, N.A.1    Donaldson, D.S.2    Ohno, H.3    Williams, I.R.4    Mahajan, A.5
  • 67
    • 73949107838 scopus 로고    scopus 로고
    • Intestinal CD103+, but not CX3CR1+, antigen sampling cells migrate in lymph and serve classical dendritic cell functions
    • Schulz, O., Jaensson, E., Persson, E.K., Liu, X., Worbs, T., Agace, W.W., Pabst, O., Intestinal CD103+, but not CX3CR1+, antigen sampling cells migrate in lymph and serve classical dendritic cell functions. J. Exp. Med. 206:13 (2009), 3101–3114.
    • (2009) J. Exp. Med. , vol.206 , Issue.13 , pp. 3101-3114
    • Schulz, O.1    Jaensson, E.2    Persson, E.K.3    Liu, X.4    Worbs, T.5    Agace, W.W.6    Pabst, O.7
  • 69
    • 34547788180 scopus 로고    scopus 로고
    • A functionally specialized population of mucosal CD103+ DCs induces Foxp3+ regulatory T cells via a TGF-beta and retinoic acid-dependent mechanism
    • Coombes, J.L., Siddiqui, K.R., Arancibia-Carcamo, C.V., Hall, J., Sun, C.M., Belkaid, Y., Powrie, F., A functionally specialized population of mucosal CD103+ DCs induces Foxp3+ regulatory T cells via a TGF-beta and retinoic acid-dependent mechanism. J. Exp. Med. 204:8 (2007), 1757–1764.
    • (2007) J. Exp. Med. , vol.204 , Issue.8 , pp. 1757-1764
    • Coombes, J.L.1    Siddiqui, K.R.2    Arancibia-Carcamo, C.V.3    Hall, J.4    Sun, C.M.5    Belkaid, Y.6    Powrie, F.7
  • 71
    • 34848902284 scopus 로고    scopus 로고
    • The impact of cell-bound antigen transport on mucosal tolerance induction
    • Pabst, O., Bernhardt, G., Forster, R., The impact of cell-bound antigen transport on mucosal tolerance induction. J. Leukoc. Biol. 82:4 (2007), 795–800.
    • (2007) J. Leukoc. Biol. , vol.82 , Issue.4 , pp. 795-800
    • Pabst, O.1    Bernhardt, G.2    Forster, R.3
  • 72
    • 33645054315 scopus 로고    scopus 로고
    • Oral tolerance originates in the intestinal immune system and relies on antigen carriage by dendritic cells
    • Worbs, T., Bode, U., Yan, S., Hoffmann, M.W., Hintzen, G., Bernhardt, G., Forster, R., Pabst, O., Oral tolerance originates in the intestinal immune system and relies on antigen carriage by dendritic cells. J. Exp. Med. 203:3 (2006), 519–527.
    • (2006) J. Exp. Med. , vol.203 , Issue.3 , pp. 519-527
    • Worbs, T.1    Bode, U.2    Yan, S.3    Hoffmann, M.W.4    Hintzen, G.5    Bernhardt, G.6    Forster, R.7    Pabst, O.8
  • 73
    • 14544293467 scopus 로고    scopus 로고
    • Compartmentalization of the mucosal immune responses to commensal intestinal bacteria
    • Macpherson, A.J., Uhr, T., Compartmentalization of the mucosal immune responses to commensal intestinal bacteria. Ann. N. Y. Acad. Sci. 1029 (2004), 36–43.
    • (2004) Ann. N. Y. Acad. Sci. , vol.1029 , pp. 36-43
    • Macpherson, A.J.1    Uhr, T.2
  • 77
    • 58149145656 scopus 로고    scopus 로고
    • Stromal mesenteric lymph node cells are essential for the generation of gut-homing T cells in vivo
    • Hammerschmidt, S.I., Ahrendt, M., Bode, U., Wahl, B., Kremmer, E., Forster, R., Pabst, O., Stromal mesenteric lymph node cells are essential for the generation of gut-homing T cells in vivo. J. Exp. Med. 205:11 (2008), 2483–2490.
    • (2008) J. Exp. Med. , vol.205 , Issue.11 , pp. 2483-2490
    • Hammerschmidt, S.I.1    Ahrendt, M.2    Bode, U.3    Wahl, B.4    Kremmer, E.5    Forster, R.6    Pabst, O.7
  • 79
    • 0036237353 scopus 로고    scopus 로고
    • Mesenteric lymph nodes are critical for the induction of high-dose oral tolerance in the absence of Peyer's patches
    • Spahn, T.W., Weiner, H.L., Rennert, P.D., Lugering, N., Fontana, A., Domschke, W., Kucharzik, T., Mesenteric lymph nodes are critical for the induction of high-dose oral tolerance in the absence of Peyer's patches. Eur. J. Immunol. 32:4 (2002), 1109–1113.
    • (2002) Eur. J. Immunol. , vol.32 , Issue.4 , pp. 1109-1113
    • Spahn, T.W.1    Weiner, H.L.2    Rennert, P.D.3    Lugering, N.4    Fontana, A.5    Domschke, W.6    Kucharzik, T.7
  • 80
    • 26844538936 scopus 로고    scopus 로고
    • Functional specialization of gut CD103+ dendritic cells in the regulation of tissue-selective T cell homing
    • Johansson-Lindbom, B., Svensson, M., Pabst, O., Palmqvist, C., Marquez, G., Forster, R., Agace, W.W., Functional specialization of gut CD103+ dendritic cells in the regulation of tissue-selective T cell homing. J. Exp. Med. 202:8 (2005), 1063–1073.
    • (2005) J. Exp. Med. , vol.202 , Issue.8 , pp. 1063-1073
    • Johansson-Lindbom, B.1    Svensson, M.2    Pabst, O.3    Palmqvist, C.4    Marquez, G.5    Forster, R.6    Agace, W.W.7
  • 84
    • 34547769253 scopus 로고    scopus 로고
    • All-trans retinoic acid mediates enhanced T reg cell growth, differentiation, and gut homing in the face of high levels of co-stimulation
    • Benson, M.J., Pino-Lagos, K., Rosemblatt, M., Noelle, R.J., All-trans retinoic acid mediates enhanced T reg cell growth, differentiation, and gut homing in the face of high levels of co-stimulation. J. Exp. Med. 204:8 (2007), 1765–1774.
    • (2007) J. Exp. Med. , vol.204 , Issue.8 , pp. 1765-1774
    • Benson, M.J.1    Pino-Lagos, K.2    Rosemblatt, M.3    Noelle, R.J.4
  • 85
    • 79951790272 scopus 로고    scopus 로고
    • CX3CR1 defines functionally distinct intestinal mononuclear phagocyte subsets which maintain their respective functions during homeostatic and inflammatory conditions
    • Weber, B., Saurer, L., Schenk, M., Dickgreber, N., Mueller, C., CX3CR1 defines functionally distinct intestinal mononuclear phagocyte subsets which maintain their respective functions during homeostatic and inflammatory conditions. Eur. J. Immunol. 41:3 (2011), 773–779.
    • (2011) Eur. J. Immunol. , vol.41 , Issue.3 , pp. 773-779
    • Weber, B.1    Saurer, L.2    Schenk, M.3    Dickgreber, N.4    Mueller, C.5
  • 86
    • 69349093381 scopus 로고    scopus 로고
    • Sequential role of plasmacytoid dendritic cells and regulatory T cells in oral tolerance
    • Dubois, B., Joubert, G., Gomez de Aguero, M., Gouanvic, M., Goubier, A., Kaiserlian, D., Sequential role of plasmacytoid dendritic cells and regulatory T cells in oral tolerance. Gastroenterology 137:3 (2009), 1019–1028.
    • (2009) Gastroenterology , vol.137 , Issue.3 , pp. 1019-1028
    • Dubois, B.1    Joubert, G.2    Gomez de Aguero, M.3    Gouanvic, M.4    Goubier, A.5    Kaiserlian, D.6
  • 88
    • 0030456670 scopus 로고    scopus 로고
    • Aerosol insulin induces regulatory CD8 gamma delta T cells that prevent murine insulin-dependent diabetes
    • Harrison, L.C., Dempsey-Collier, M., Kramer, D.R., Takahashi, K., Aerosol insulin induces regulatory CD8 gamma delta T cells that prevent murine insulin-dependent diabetes. J. Exp. Med. 184:6 (1996), 2167–2174.
    • (1996) J. Exp. Med. , vol.184 , Issue.6 , pp. 2167-2174
    • Harrison, L.C.1    Dempsey-Collier, M.2    Kramer, D.R.3    Takahashi, K.4
  • 89
    • 0029923430 scopus 로고    scopus 로고
    • Nasal administration of glutamate decarboxylase (GAD65) peptides induces Th2 responses and prevents murine insulin-dependent diabetes
    • Tian, J., Atkinson, M.A., Clare-Salzler, M., Herschenfeld, A., Forsthuber, T., Lehmann, P.V., Kaufman, D.L., Nasal administration of glutamate decarboxylase (GAD65) peptides induces Th2 responses and prevents murine insulin-dependent diabetes. J. Exp. Med. 183:4 (1996), 1561–1567.
    • (1996) J. Exp. Med. , vol.183 , Issue.4 , pp. 1561-1567
    • Tian, J.1    Atkinson, M.A.2    Clare-Salzler, M.3    Herschenfeld, A.4    Forsthuber, T.5    Lehmann, P.V.6    Kaufman, D.L.7
  • 90
    • 0033563161 scopus 로고    scopus 로고
    • Mechanisms of nasal tolerance induction in experimental autoimmune myasthenia gravis: identification of regulatory cells
    • Shi, F.D., Li, H., Wang, H., Bai, X., van der Meide, P.H., Link, H., Ljunggren, H.G., Mechanisms of nasal tolerance induction in experimental autoimmune myasthenia gravis: identification of regulatory cells. J. Immunol. 162:10 (1999), 5757–5763.
    • (1999) J. Immunol. , vol.162 , Issue.10 , pp. 5757-5763
    • Shi, F.D.1    Li, H.2    Wang, H.3    Bai, X.4    van der Meide, P.H.5    Link, H.6    Ljunggren, H.G.7
  • 91
    • 84879627201 scopus 로고    scopus 로고
    • Cutting edge: inhaled antigen upregulates retinaldehyde dehydrogenase in lung CD103+ but not plasmacytoid dendritic cells to induce Foxp3 de novo in CD4+ T cells and promote airway tolerance
    • Khare, A., Krishnamoorthy, N., Oriss, T.B., Fei, M., Ray, P., Ray, A., Cutting edge: inhaled antigen upregulates retinaldehyde dehydrogenase in lung CD103+ but not plasmacytoid dendritic cells to induce Foxp3 de novo in CD4+ T cells and promote airway tolerance. J. Immunol. 191:1 (2013), 25–29.
    • (2013) J. Immunol. , vol.191 , Issue.1 , pp. 25-29
    • Khare, A.1    Krishnamoorthy, N.2    Oriss, T.B.3    Fei, M.4    Ray, P.5    Ray, A.6
  • 92
    • 0037836974 scopus 로고    scopus 로고
    • Evaluation of novel aerosol formulations designed for mucosal vaccination against influenza virus
    • Smith, D.J., Bot, S., Dellamary, L., Bot, A., Evaluation of novel aerosol formulations designed for mucosal vaccination against influenza virus. Vaccine 21:21–22 (2003), 2805–2812.
    • (2003) Vaccine , vol.21 , Issue.21-22 , pp. 2805-2812
    • Smith, D.J.1    Bot, S.2    Dellamary, L.3    Bot, A.4
  • 93
    • 80051568013 scopus 로고    scopus 로고
    • Potential of nasopharynx-associated lymphoid tissue for vaccine responses in the airways
    • Brandtzaeg, P., Potential of nasopharynx-associated lymphoid tissue for vaccine responses in the airways. Am. J. Respir. Crit. Care Med. 183:12 (2011), 1595–1604.
    • (2011) Am. J. Respir. Crit. Care Med. , vol.183 , Issue.12 , pp. 1595-1604
    • Brandtzaeg, P.1
  • 96
    • 84939568357 scopus 로고    scopus 로고
    • Mucosal vaccination by the intranasal route. Nose-associated lymphoid tissue (NALT)-Structure, function and species differences
    • Pabst, R., Mucosal vaccination by the intranasal route. Nose-associated lymphoid tissue (NALT)-Structure, function and species differences. Vaccine 33:36 (2015), 4406–4413.
    • (2015) Vaccine , vol.33 , Issue.36 , pp. 4406-4413
    • Pabst, R.1
  • 98
    • 0033557738 scopus 로고    scopus 로고
    • Intranasally induced immunological tolerance is determined by characteristics of the draining lymph nodes: studies with OVA and human cartilage gp-39
    • Wolvers, D.A., Coenen-de Roo, C.J., Mebius, R.E., van der Cammen, M.J., Tirion, F., Miltenburg, A.M., Kraal, G., Intranasally induced immunological tolerance is determined by characteristics of the draining lymph nodes: studies with OVA and human cartilage gp-39. J. Immunol. 162:4 (1999), 1994–1998.
    • (1999) J. Immunol. , vol.162 , Issue.4 , pp. 1994-1998
    • Wolvers, D.A.1    Coenen-de Roo, C.J.2    Mebius, R.E.3    van der Cammen, M.J.4    Tirion, F.5    Miltenburg, A.M.6    Kraal, G.7
  • 99
    • 23344438931 scopus 로고    scopus 로고
    • Bronchus- and nasal-associated lymphoid tissues
    • Bienenstock, J., McDermott, M.R., Bronchus- and nasal-associated lymphoid tissues. Immunol. Rev. 206 (2005), 22–31.
    • (2005) Immunol. Rev. , vol.206 , pp. 22-31
    • Bienenstock, J.1    McDermott, M.R.2
  • 101
    • 0025469569 scopus 로고
    • Is the bronchus-associated lymphoid tissue (BALT) an integral structure of the lung in normal mammals, including humans?
    • Pabst, R., Gehrke, I., Is the bronchus-associated lymphoid tissue (BALT) an integral structure of the lung in normal mammals, including humans?. Am. J. Respir. Cell Mol. Biol. 3:2 (1990), 131–135.
    • (1990) Am. J. Respir. Cell Mol. Biol. , vol.3 , Issue.2 , pp. 131-135
    • Pabst, R.1    Gehrke, I.2
  • 102
    • 0027530535 scopus 로고
    • Bronchus-associated lymphoid tissue (BALT) in human fetal and infant lung
    • Gould, S.J., Isaacson, P.G., Bronchus-associated lymphoid tissue (BALT) in human fetal and infant lung. J. Pathol. 169:2 (1993), 229–234.
    • (1993) J. Pathol. , vol.169 , Issue.2 , pp. 229-234
    • Gould, S.J.1    Isaacson, P.G.2
  • 103
    • 0031889355 scopus 로고    scopus 로고
    • Bronchus-associated lymphoid tissue (BALT) and larynx-associated lymphoid tissue (LALT) are found at different frequencies in children, adolescents and adults
    • Hiller, A.S., Tschernig, T., Kleemann, W.J., Pabst, R., Bronchus-associated lymphoid tissue (BALT) and larynx-associated lymphoid tissue (LALT) are found at different frequencies in children, adolescents and adults. Scand. J. Immunol. 47:2 (1998), 159–162.
    • (1998) Scand. J. Immunol. , vol.47 , Issue.2 , pp. 159-162
    • Hiller, A.S.1    Tschernig, T.2    Kleemann, W.J.3    Pabst, R.4
  • 104
    • 0033935484 scopus 로고    scopus 로고
    • Bronchus-associated lymphoid tissue (BALT) is not present in the normal adult lung but in different diseases
    • Tschernig, T., Pabst, R., Bronchus-associated lymphoid tissue (BALT) is not present in the normal adult lung but in different diseases. Pathobiology 68:1 (2000), 1–8.
    • (2000) Pathobiology , vol.68 , Issue.1 , pp. 1-8
    • Tschernig, T.1    Pabst, R.2
  • 106
    • 80054919389 scopus 로고    scopus 로고
    • Secretory IgA's complex roles in immunity and mucosal homeostasis in the gut
    • Mantis, N.J., Rol, N., Corthesy, B., Secretory IgA's complex roles in immunity and mucosal homeostasis in the gut. Mucosal Immunol. 4:6 (2011), 603–611.
    • (2011) Mucosal Immunol. , vol.4 , Issue.6 , pp. 603-611
    • Mantis, N.J.1    Rol, N.2    Corthesy, B.3
  • 107
    • 0015106394 scopus 로고
    • Cell-mediated immunity and antibody responses in the respiratory tract after local and systemic immunization
    • Waldman, R.H., Henney, C.S., Cell-mediated immunity and antibody responses in the respiratory tract after local and systemic immunization. J. Exp. Med. 134:2 (1971), 482–494.
    • (1971) J. Exp. Med. , vol.134 , Issue.2 , pp. 482-494
    • Waldman, R.H.1    Henney, C.S.2
  • 108
    • 3142720367 scopus 로고    scopus 로고
    • Essential role of lung plasmacytoid dendritic cells in preventing asthmatic reactions to harmless inhaled antigen
    • de Heer, H.J., Hammad, H., Soullie, T., Hijdra, D., Vos, N., Willart, M.A., Hoogsteden, H.C., Lambrecht, B.N., Essential role of lung plasmacytoid dendritic cells in preventing asthmatic reactions to harmless inhaled antigen. J. Exp. Med. 200:1 (2004), 89–98.
    • (2004) J. Exp. Med. , vol.200 , Issue.1 , pp. 89-98
    • de Heer, H.J.1    Hammad, H.2    Soullie, T.3    Hijdra, D.4    Vos, N.5    Willart, M.A.6    Hoogsteden, H.C.7    Lambrecht, B.N.8
  • 109
    • 77950408684 scopus 로고    scopus 로고
    • Skin-draining lymph nodes contain dermis-derived CD103(−) dendritic cells that constitutively produce retinoic acid and induce Foxp3(+) regulatory T cells
    • Guilliams, M., Crozat, K., Henri, S., Tamoutounour, S., Grenot, P., Devilard, E., de Bovis, B., Alexopoulou, L., Dalod, M., Malissen, B., Skin-draining lymph nodes contain dermis-derived CD103(−) dendritic cells that constitutively produce retinoic acid and induce Foxp3(+) regulatory T cells. Blood 115:10 (2010), 1958–1968.
    • (2010) Blood , vol.115 , Issue.10 , pp. 1958-1968
    • Guilliams, M.1    Crozat, K.2    Henri, S.3    Tamoutounour, S.4    Grenot, P.5    Devilard, E.6    de Bovis, B.7    Alexopoulou, L.8    Dalod, M.9    Malissen, B.10
  • 110
    • 84864857933 scopus 로고    scopus 로고
    • CD8alpha(+)beta(−) and CD8alpha(+)beta(+) plasmacytoid dendritic cells induce Foxp3(+) regulatory T cells and prevent the induction of airway hyper-reactivity
    • Lombardi, V., Speak, A.O., Kerzerho, J., Szely, N., Akbari, O., CD8alpha(+)beta(−) and CD8alpha(+)beta(+) plasmacytoid dendritic cells induce Foxp3(+) regulatory T cells and prevent the induction of airway hyper-reactivity. Mucosal Immunol. 5:4 (2012), 432–443.
    • (2012) Mucosal Immunol. , vol.5 , Issue.4 , pp. 432-443
    • Lombardi, V.1    Speak, A.O.2    Kerzerho, J.3    Szely, N.4    Akbari, O.5
  • 112
    • 0029063115 scopus 로고
    • Gamma delta T cells down-regulate primary IgE responses in rats to inhaled soluble protein antigens
    • McMenamin, C., McKersey, M., Kuhnlein, P., Hunig, T., Holt, P.G., Gamma delta T cells down-regulate primary IgE responses in rats to inhaled soluble protein antigens. J. Immunol. 154:9 (1995), 4390–4394.
    • (1995) J. Immunol. , vol.154 , Issue.9 , pp. 4390-4394
    • McMenamin, C.1    McKersey, M.2    Kuhnlein, P.3    Hunig, T.4    Holt, P.G.5
  • 113
    • 0027993367 scopus 로고
    • Regulation of IgE responses to inhaled antigen in mice by antigen-specific gamma delta T cells
    • McMenamin, C., Pimm, C., McKersey, M., Holt, P.G., Regulation of IgE responses to inhaled antigen in mice by antigen-specific gamma delta T cells. Science 265:5180 (1994), 1869–1871.
    • (1994) Science , vol.265 , Issue.5180 , pp. 1869-1871
    • McMenamin, C.1    Pimm, C.2    McKersey, M.3    Holt, P.G.4
  • 114
    • 0342858883 scopus 로고    scopus 로고
    • Ultrastructural study on the follicle-associated epithelium of nasal-associated lymphoid tissue in specific pathogen-free (SPF) and conventional environment-adapted (SPF-CV) rats
    • Jeong, K.I., Suzuki, H., Nakayama, H., Doi, K., Ultrastructural study on the follicle-associated epithelium of nasal-associated lymphoid tissue in specific pathogen-free (SPF) and conventional environment-adapted (SPF-CV) rats. J. Anat. 196:Pt 3 (2000), 443–451.
    • (2000) J. Anat. , vol.196 , pp. 443-451
    • Jeong, K.I.1    Suzuki, H.2    Nakayama, H.3    Doi, K.4
  • 115
    • 0029883626 scopus 로고    scopus 로고
    • History of oral tolerance and mucosal immunity
    • Brandtzaeg, P., History of oral tolerance and mucosal immunity. Ann. N. Y. Acad. Sci. 778 (1996), 1–27.
    • (1996) Ann. N. Y. Acad. Sci. , vol.778 , pp. 1-27
    • Brandtzaeg, P.1
  • 117
    • 0021850386 scopus 로고
    • Induction of IgE-secreting cells and IgE isotype-specific suppressor T cells in the respiratory lymph nodes of rats in response to antigen inhalation
    • Sedgwick, J.D., Holt, P.G., Induction of IgE-secreting cells and IgE isotype-specific suppressor T cells in the respiratory lymph nodes of rats in response to antigen inhalation. Cell. Immunol. 94:1 (1985), 182–194.
    • (1985) Cell. Immunol. , vol.94 , Issue.1 , pp. 182-194
    • Sedgwick, J.D.1    Holt, P.G.2
  • 119
    • 80051904734 scopus 로고    scopus 로고
    • Thymic stromal lymphopoetin-induced expression of the endogenous inhibitory enzyme SLPI mediates recovery from colonic inflammation
    • Reardon, C., Lechmann, M., Brustle, A., Gareau, M.G., Shuman, N., Philpott, D., Ziegler, S.F., Mak, T.W., Thymic stromal lymphopoetin-induced expression of the endogenous inhibitory enzyme SLPI mediates recovery from colonic inflammation. Immunity 35:2 (2011), 223–235.
    • (2011) Immunity , vol.35 , Issue.2 , pp. 223-235
    • Reardon, C.1    Lechmann, M.2    Brustle, A.3    Gareau, M.G.4    Shuman, N.5    Philpott, D.6    Ziegler, S.F.7    Mak, T.W.8
  • 120
    • 0033003599 scopus 로고    scopus 로고
    • Oral tolerance in disease
    • Garside, P., Mowat, A.M., Khoruts, A., Oral tolerance in disease. Gut 44:1 (1999), 137–142.
    • (1999) Gut , vol.44 , Issue.1 , pp. 137-142
    • Garside, P.1    Mowat, A.M.2    Khoruts, A.3
  • 121
    • 0023858086 scopus 로고
    • Suppression of experimental autoimmune encephalomyelitis by oral administration of myelin basic protein and its fragments
    • Higgins, P.J., Weiner, H.L., Suppression of experimental autoimmune encephalomyelitis by oral administration of myelin basic protein and its fragments. J. Immunol. 140:2 (1988), 440–445.
    • (1988) J. Immunol. , vol.140 , Issue.2 , pp. 440-445
    • Higgins, P.J.1    Weiner, H.L.2
  • 122
    • 0000253355 scopus 로고
    • Suppression of type II collagen-induced arthritis by intragastric administration of soluble type II collagen
    • Nagler-Anderson, C., Bober, L.A., Robinson, M.E., Siskind, G.W., Thorbecke, G.J., Suppression of type II collagen-induced arthritis by intragastric administration of soluble type II collagen. Proc. Natl. Acad. Sci. U. S. A. 83:19 (1986), 7443–7446.
    • (1986) Proc. Natl. Acad. Sci. U. S. A. , vol.83 , Issue.19 , pp. 7443-7446
    • Nagler-Anderson, C.1    Bober, L.A.2    Robinson, M.E.3    Siskind, G.W.4    Thorbecke, G.J.5
  • 123
    • 84995609114 scopus 로고    scopus 로고
    • IgE-associated allergic disorders: recent advances in etiology, diagnosis, and treatment
    • Zellweger, F., Eggel, A., IgE-associated allergic disorders: recent advances in etiology, diagnosis, and treatment. Allergy 71:12 (2016), 1652–1661.
    • (2016) Allergy , vol.71 , Issue.12 , pp. 1652-1661
    • Zellweger, F.1    Eggel, A.2
  • 124
    • 0019505760 scopus 로고
    • Inhibition of specific IgE responses in mice by pre-exposure to inhaled antigen
    • Holt, P.G., Batty, J.E., Turner, K.J., Inhibition of specific IgE responses in mice by pre-exposure to inhaled antigen. Immunology 42:3 (1981), 409–417.
    • (1981) Immunology , vol.42 , Issue.3 , pp. 409-417
    • Holt, P.G.1    Batty, J.E.2    Turner, K.J.3
  • 126
    • 17944365808 scopus 로고    scopus 로고
    • Intranasal treatment with a recombinant hypoallergenic derivative of the major birch pollen allergen Bet v 1 prevents allergic sensitization and airway inflammation in mice
    • Wiedermann, U., Herz, U., Baier, K., Vrtala, S., Neuhaus-Steinmetz, U., Bohle, B., Dekan, G., Renz, H., Ebner, C., Valenta, R., Kraft, D., Intranasal treatment with a recombinant hypoallergenic derivative of the major birch pollen allergen Bet v 1 prevents allergic sensitization and airway inflammation in mice. Int. Arch. Allergy Immunol. 126:1 (2001), 68–77.
    • (2001) Int. Arch. Allergy Immunol. , vol.126 , Issue.1 , pp. 68-77
    • Wiedermann, U.1    Herz, U.2    Baier, K.3    Vrtala, S.4    Neuhaus-Steinmetz, U.5    Bohle, B.6    Dekan, G.7    Renz, H.8    Ebner, C.9    Valenta, R.10    Kraft, D.11
  • 127
    • 0032836876 scopus 로고    scopus 로고
    • Suppression of antigen-specific T- and B-cell responses by intranasal or oral administration of recombinant bet v 1, the major birch pollen allergen, in a murine model of type I allergy
    • Wiedermann, U., Jahn-Schmid, B., Bohle, B., Repa, A., Renz, H., Kraft, D., Ebner, C., Suppression of antigen-specific T- and B-cell responses by intranasal or oral administration of recombinant bet v 1, the major birch pollen allergen, in a murine model of type I allergy. J. Allergy Clin. Immunol. 103:6 (1999), 1202–1210.
    • (1999) J. Allergy Clin. Immunol. , vol.103 , Issue.6 , pp. 1202-1210
    • Wiedermann, U.1    Jahn-Schmid, B.2    Bohle, B.3    Repa, A.4    Renz, H.5    Kraft, D.6    Ebner, C.7
  • 128
    • 54449093890 scopus 로고    scopus 로고
    • Airway inflammation induced after allergic poly-sensitization can be prevented by mucosal but not by systemic administration of poly-peptides
    • Hufnagl, K., Focke, M., Gruber, F., Hufnagl, P., Loupal, G., Scheiner, O., Wiedermann, U., Airway inflammation induced after allergic poly-sensitization can be prevented by mucosal but not by systemic administration of poly-peptides. Clin. Exp. Allergy 38:7 (2008), 1192–1202.
    • (2008) Clin. Exp. Allergy , vol.38 , Issue.7 , pp. 1192-1202
    • Hufnagl, K.1    Focke, M.2    Gruber, F.3    Hufnagl, P.4    Loupal, G.5    Scheiner, O.6    Wiedermann, U.7
  • 132
    • 34447308554 scopus 로고    scopus 로고
    • Sublingual ‘oral tolerance’ induction with antigen conjugated to cholera toxin B subunit generates regulatory T cells that induce apoptosis and depletion of effector T cells
    • Sun, J.B., Czerkinsky, C., Holmgren, J., Sublingual ‘oral tolerance’ induction with antigen conjugated to cholera toxin B subunit generates regulatory T cells that induce apoptosis and depletion of effector T cells. Scand. J. Immunol. 66:2-3 (2007), 278–286.
    • (2007) Scand. J. Immunol. , vol.66 , Issue.2-3 , pp. 278-286
    • Sun, J.B.1    Czerkinsky, C.2    Holmgren, J.3
  • 133
    • 72349096793 scopus 로고    scopus 로고
    • Mucosally induced immunological tolerance, regulatory T cells and the adjuvant effect by cholera toxin B subunit
    • Sun, J.B., Czerkinsky, C., Holmgren, J., Mucosally induced immunological tolerance, regulatory T cells and the adjuvant effect by cholera toxin B subunit. Scand. J. Immunol. 71:1 (2010), 1–11.
    • (2010) Scand. J. Immunol. , vol.71 , Issue.1 , pp. 1-11
    • Sun, J.B.1    Czerkinsky, C.2    Holmgren, J.3
  • 134
    • 84957941850 scopus 로고    scopus 로고
    • Vaccine development for allergen-specific immunotherapy based on recombinant allergens and synthetic allergen peptides: lessons from the past and novel mechanisms of action for the future
    • Valenta, R., Campana, R., Focke-Tejkl, M., Niederberger, V., Vaccine development for allergen-specific immunotherapy based on recombinant allergens and synthetic allergen peptides: lessons from the past and novel mechanisms of action for the future. J. Allergy Clin. Immunol. 137:2 (2016), 351–357.
    • (2016) J. Allergy Clin. Immunol. , vol.137 , Issue.2 , pp. 351-357
    • Valenta, R.1    Campana, R.2    Focke-Tejkl, M.3    Niederberger, V.4
  • 137
    • 84861963114 scopus 로고    scopus 로고
    • Mechanisms underlying allergy vaccination with recombinant hypoallergenic allergen derivatives
    • Linhart, B., Valenta, R., Mechanisms underlying allergy vaccination with recombinant hypoallergenic allergen derivatives. Vaccine 30:29 (2012), 4328–4335.
    • (2012) Vaccine , vol.30 , Issue.29 , pp. 4328-4335
    • Linhart, B.1    Valenta, R.2
  • 139
    • 1042274839 scopus 로고    scopus 로고
    • Animal models of type I allergy using recombinant allergens
    • Herz, U., Renz, H., Wiedermann, U., Animal models of type I allergy using recombinant allergens. Methods 32:3 (2004), 271–280.
    • (2004) Methods , vol.32 , Issue.3 , pp. 271-280
    • Herz, U.1    Renz, H.2    Wiedermann, U.3
  • 140
    • 84990205375 scopus 로고    scopus 로고
    • Review of mouse models applied to the study of asthma
    • Marques-Garcia, F., Marcos-Vadillo, E., Review of mouse models applied to the study of asthma. Methods Mol. Biol. 1434 (2016), 213–222.
    • (2016) Methods Mol. Biol. , vol.1434 , pp. 213-222
    • Marques-Garcia, F.1    Marcos-Vadillo, E.2
  • 141
    • 1642372399 scopus 로고    scopus 로고
    • Prolonged allergen challenge in mice leads to persistent airway remodelling
    • McMillan, S.J., Lloyd, C.M., Prolonged allergen challenge in mice leads to persistent airway remodelling. Clin. Exp. Allergy 34:3 (2004), 497–507.
    • (2004) Clin. Exp. Allergy , vol.34 , Issue.3 , pp. 497-507
    • McMillan, S.J.1    Lloyd, C.M.2
  • 143
    • 0028278872 scopus 로고
    • Animal models of occupational asthma
    • Karol, M.H., Animal models of occupational asthma. Eur. Respir. J. 7:3 (1994), 555–568.
    • (1994) Eur. Respir. J. , vol.7 , Issue.3 , pp. 555-568
    • Karol, M.H.1
  • 144
    • 47749116885 scopus 로고    scopus 로고
    • The classical ovalbumin challenge model of asthma in mice
    • Kumar, R.K., Herbert, C., Foster, P.S., The classical ovalbumin challenge model of asthma in mice. Curr. Drug Targets 9:6 (2008), 485–494.
    • (2008) Curr. Drug Targets , vol.9 , Issue.6 , pp. 485-494
    • Kumar, R.K.1    Herbert, C.2    Foster, P.S.3
  • 145
    • 0034529318 scopus 로고    scopus 로고
    • Antigen-induced mucosal T cell activation is followed by Th1 T cell suppression in continuously fed ovalbumin TCR-transgenic mice
    • Marth, T., Ring, S., Schulte, D., Klensch, N., Strober, W., Kelsall, B.L., Stallmach, A., Zeitz, M., Antigen-induced mucosal T cell activation is followed by Th1 T cell suppression in continuously fed ovalbumin TCR-transgenic mice. Eur. J. Immunol. 30:12 (2000), 3478–3486.
    • (2000) Eur. J. Immunol. , vol.30 , Issue.12 , pp. 3478-3486
    • Marth, T.1    Ring, S.2    Schulte, D.3    Klensch, N.4    Strober, W.5    Kelsall, B.L.6    Stallmach, A.7    Zeitz, M.8
  • 146
    • 80053562644 scopus 로고    scopus 로고
    • The role of innate immunity activation in house dust mite allergy
    • Jacquet, A., The role of innate immunity activation in house dust mite allergy. Trends Mol. Med. 17:10 (2011), 604–611.
    • (2011) Trends Mol. Med. , vol.17 , Issue.10 , pp. 604-611
    • Jacquet, A.1
  • 147
    • 0032768515 scopus 로고    scopus 로고
    • Suppressive versus stimulatory effects of allergen/cholera toxoid (CTB) conjugates depending on the nature of the allergen in a murine model of type I allergy
    • Wiedermann, U., Jahn-Schmid, B., Lindblad, M., Rask, C., Holmgren, J., Kraft, D., Ebner, C., Suppressive versus stimulatory effects of allergen/cholera toxoid (CTB) conjugates depending on the nature of the allergen in a murine model of type I allergy. Int. Immunol. 11:7 (1999), 1131–1138.
    • (1999) Int. Immunol. , vol.11 , Issue.7 , pp. 1131-1138
    • Wiedermann, U.1    Jahn-Schmid, B.2    Lindblad, M.3    Rask, C.4    Holmgren, J.5    Kraft, D.6    Ebner, C.7
  • 148
    • 64149087970 scopus 로고    scopus 로고
    • House dust mite allergen induces asthma via Toll-like receptor 4 triggering of airway structural cells
    • Hammad, H., Chieppa, M., Perros, F., Willart, M.A., Germain, R.N., Lambrecht, B.N., House dust mite allergen induces asthma via Toll-like receptor 4 triggering of airway structural cells. Nat. Med. 15:4 (2009), 410–416.
    • (2009) Nat. Med. , vol.15 , Issue.4 , pp. 410-416
    • Hammad, H.1    Chieppa, M.2    Perros, F.3    Willart, M.A.4    Germain, R.N.5    Lambrecht, B.N.6
  • 151
    • 0033863165 scopus 로고    scopus 로고
    • Chronic allergen challenge as an experimental model: necessary, significant or useful?
    • Leckie, M.J., Chronic allergen challenge as an experimental model: necessary, significant or useful?. Clin. Exp. Allergy 30:9 (2000), 1191–1193.
    • (2000) Clin. Exp. Allergy , vol.30 , Issue.9 , pp. 1191-1193
    • Leckie, M.J.1
  • 152
    • 33644910900 scopus 로고    scopus 로고
    • The role of Foxp3+ T cells in long-term efficacy of prophylactic and therapeutic mucosal tolerance induction in mice
    • Winkler, B., Hufnagl, K., Spittler, A., Ploder, M., Kallay, E., Vrtala, S., Valenta, R., Kundi, M., Renz, H., Wiedermann, U., The role of Foxp3+ T cells in long-term efficacy of prophylactic and therapeutic mucosal tolerance induction in mice. Allergy 61:2 (2006), 173–180.
    • (2006) Allergy , vol.61 , Issue.2 , pp. 173-180
    • Winkler, B.1    Hufnagl, K.2    Spittler, A.3    Ploder, M.4    Kallay, E.5    Vrtala, S.6    Valenta, R.7    Kundi, M.8    Renz, H.9    Wiedermann, U.10
  • 154
    • 23244456566 scopus 로고    scopus 로고
    • Intranasal tolerance induction with polypeptides derived from 3 noncross-reactive major aeroallergens prevents allergic polysensitization in mice
    • Hufnagl, K., Winkler, B., Focke, M., Valenta, R., Scheiner, O., Renz, H., Wiedermann, U., Intranasal tolerance induction with polypeptides derived from 3 noncross-reactive major aeroallergens prevents allergic polysensitization in mice. J. Allergy Clin. Immunol. 116:2 (2005), 370–376.
    • (2005) J. Allergy Clin. Immunol. , vol.116 , Issue.2 , pp. 370-376
    • Hufnagl, K.1    Winkler, B.2    Focke, M.3    Valenta, R.4    Scheiner, O.5    Renz, H.6    Wiedermann, U.7
  • 155
    • 34548242742 scopus 로고    scopus 로고
    • Intranasal immunization with a dominant T-cell epitope peptide of a major allergen of olive pollen prevents mice from sensitization to the whole allergen
    • Marazuela, E.G., Rodriguez, R., Fernandez-Garcia, H., Garcia, M.S., Villalba, M., Batanero, E., Intranasal immunization with a dominant T-cell epitope peptide of a major allergen of olive pollen prevents mice from sensitization to the whole allergen. Mol. Immunol. 45:2 (2008), 438–445.
    • (2008) Mol. Immunol. , vol.45 , Issue.2 , pp. 438-445
    • Marazuela, E.G.1    Rodriguez, R.2    Fernandez-Garcia, H.3    Garcia, M.S.4    Villalba, M.5    Batanero, E.6
  • 156
    • 33344457434 scopus 로고    scopus 로고
    • Prophylactic intranasal treatment with fragments of 1,3-beta-glucanase olive pollen allergen prevents airway inflammation in a murine model of type I allergy
    • Palomares, O., Batanero, E., Canamero, M., Villalba, M., Rodriguez, R., Prophylactic intranasal treatment with fragments of 1,3-beta-glucanase olive pollen allergen prevents airway inflammation in a murine model of type I allergy. Int. Arch. Allergy Immunol. 139:3 (2006), 175–180.
    • (2006) Int. Arch. Allergy Immunol. , vol.139 , Issue.3 , pp. 175-180
    • Palomares, O.1    Batanero, E.2    Canamero, M.3    Villalba, M.4    Rodriguez, R.5
  • 157
    • 84896695214 scopus 로고    scopus 로고
    • The spectrum of olive pollen allergens. From structures to diagnosis and treatment
    • Villalba, M., Rodriguez, R., Batanero, E., The spectrum of olive pollen allergens. From structures to diagnosis and treatment. Methods 66:1 (2014), 44–54.
    • (2014) Methods , vol.66 , Issue.1 , pp. 44-54
    • Villalba, M.1    Rodriguez, R.2    Batanero, E.3
  • 159
    • 0027451437 scopus 로고
    • Inhibition of T cell and antibody responses to house dust mite allergen by inhalation of the dominant T cell epitope in naive and sensitized mice
    • Hoyne, G.F., O'Hehir, R.E., Wraith, D.C., Thomas, W.R., Lamb, J.R., Inhibition of T cell and antibody responses to house dust mite allergen by inhalation of the dominant T cell epitope in naive and sensitized mice. J. Exp. Med. 178:5 (1993), 1783–1788.
    • (1993) J. Exp. Med. , vol.178 , Issue.5 , pp. 1783-1788
    • Hoyne, G.F.1    O'Hehir, R.E.2    Wraith, D.C.3    Thomas, W.R.4    Lamb, J.R.5
  • 160
    • 0034776179 scopus 로고    scopus 로고
    • Inhibition of mucosal and systemic T(h)2-type immune responses by intranasal peptides containing a dominant T cell epitope of the allergen Der p 1
    • Jarnicki, A.G., Tsuji, T., Thomas, W.R., Inhibition of mucosal and systemic T(h)2-type immune responses by intranasal peptides containing a dominant T cell epitope of the allergen Der p 1. Int. Immunol. 13:10 (2001), 1223–1231.
    • (2001) Int. Immunol. , vol.13 , Issue.10 , pp. 1223-1231
    • Jarnicki, A.G.1    Tsuji, T.2    Thomas, W.R.3
  • 162
    • 68249141397 scopus 로고    scopus 로고
    • Suppression of allergic airway inflammation in a mouse model by Der p2 recombined BCG
    • Ou-Yang, H.F., Hu, X.B., Ti, X.Y., Shi, J.R., Li, S.J., Qi, H.W., Wu, C.G., Suppression of allergic airway inflammation in a mouse model by Der p2 recombined BCG. Immunology 128:1 Suppl (2009), e343–352.
    • (2009) Immunology , vol.128 , Issue.1 , pp. e343-352
    • Ou-Yang, H.F.1    Hu, X.B.2    Ti, X.Y.3    Shi, J.R.4    Li, S.J.5    Qi, H.W.6    Wu, C.G.7
  • 164
    • 85006827248 scopus 로고    scopus 로고
    • House dust mite-driven asthma and allergen-specific T cells depend on B cells when the amount of inhaled allergen is limiting
    • Dullaers, M., Schuijs, M.J., Willart, M., Fierens, K., Van Moorleghem, J., Hammad, H., Lambrecht, B.N., House dust mite-driven asthma and allergen-specific T cells depend on B cells when the amount of inhaled allergen is limiting. J. Allergy Clin. Immunol. 140:1 (2017), 76–88.
    • (2017) J. Allergy Clin. Immunol. , vol.140 , Issue.1 , pp. 76-88
    • Dullaers, M.1    Schuijs, M.J.2    Willart, M.3    Fierens, K.4    Van Moorleghem, J.5    Hammad, H.6    Lambrecht, B.N.7
  • 166
    • 85003874428 scopus 로고    scopus 로고
    • Development of eosinophilic inflammation is independent of B-T cell interaction in a chronic house dust mite-driven asthma model
    • Vroman, H., Bergen, I.M., Li, B.W., van Hulst, J.A., Lukkes, M., van Uden, D., Hendriks, R.W., Kool, M., Development of eosinophilic inflammation is independent of B-T cell interaction in a chronic house dust mite-driven asthma model. Clin. Exp. Allergy 47:4 (2017), 551–564.
    • (2017) Clin. Exp. Allergy , vol.47 , Issue.4 , pp. 551-564
    • Vroman, H.1    Bergen, I.M.2    Li, B.W.3    van Hulst, J.A.4    Lukkes, M.5    van Uden, D.6    Hendriks, R.W.7    Kool, M.8
  • 167
    • 0027323846 scopus 로고
    • Peripheral T-cell tolerance induced in naive and primed mice by subcutaneous injection of peptides from the major cat allergen Fel d I
    • Briner, T.J., Kuo, M.C., Keating, K.M., Rogers, B.L., Greenstein, J.L., Peripheral T-cell tolerance induced in naive and primed mice by subcutaneous injection of peptides from the major cat allergen Fel d I. Proc. Natl. Acad. Sci. U. S. A. 90:16 (1993), 7608–7612.
    • (1993) Proc. Natl. Acad. Sci. U. S. A. , vol.90 , Issue.16 , pp. 7608-7612
    • Briner, T.J.1    Kuo, M.C.2    Keating, K.M.3    Rogers, B.L.4    Greenstein, J.L.5
  • 169
    • 84929309946 scopus 로고    scopus 로고
    • Immunoregulatory T cell epitope peptides: the new frontier in allergy therapy
    • Prickett, S.R., Rolland, J.M., O'Hehir, R.E., Immunoregulatory T cell epitope peptides: the new frontier in allergy therapy. Clin. Exp. Allergy 45:6 (2015), 1015–1026.
    • (2015) Clin. Exp. Allergy , vol.45 , Issue.6 , pp. 1015-1026
    • Prickett, S.R.1    Rolland, J.M.2    O'Hehir, R.E.3
  • 170
    • 0031054483 scopus 로고    scopus 로고
    • Modulation of the allergic immune response in BALB/c mice by subcutaneous injection of high doses of the dominant T cell epitope from the major birch pollen allergen Bet v 1
    • Bauer, L., Bohle, B., Jahn-Schmid, B., Wiedermann, U., Daser, A., Renz, H., Kraft, D., Ebner, C., Modulation of the allergic immune response in BALB/c mice by subcutaneous injection of high doses of the dominant T cell epitope from the major birch pollen allergen Bet v 1. Clin. Exp. Immunol. 107:3 (1997), 536–541.
    • (1997) Clin. Exp. Immunol. , vol.107 , Issue.3 , pp. 536-541
    • Bauer, L.1    Bohle, B.2    Jahn-Schmid, B.3    Wiedermann, U.4    Daser, A.5    Renz, H.6    Kraft, D.7    Ebner, C.8
  • 171
    • 0032747878 scopus 로고    scopus 로고
    • Age-dependent tendency to become sensitized to other classes of aeroallergens in atopic asthmatic children
    • Silvestri, M., Rossi, G.A., Cozzani, S., Pulvirenti, G., Fasce, L., Age-dependent tendency to become sensitized to other classes of aeroallergens in atopic asthmatic children. Ann. Allergy Asthma Immunol. 83:4 (1999), 335–340.
    • (1999) Ann. Allergy Asthma Immunol. , vol.83 , Issue.4 , pp. 335-340
    • Silvestri, M.1    Rossi, G.A.2    Cozzani, S.3    Pulvirenti, G.4    Fasce, L.5
  • 172
    • 84867541432 scopus 로고    scopus 로고
    • House dust mite allergic airway inflammation facilitates neosensitization to inhaled allergen in mice
    • van Rijt, L.S., Logiantara, A., Utsch, L., Canbaz, D., Boon, L., van Ree, R., House dust mite allergic airway inflammation facilitates neosensitization to inhaled allergen in mice. Allergy 67:11 (2012), 1383–1391.
    • (2012) Allergy , vol.67 , Issue.11 , pp. 1383-1391
    • van Rijt, L.S.1    Logiantara, A.2    Utsch, L.3    Canbaz, D.4    Boon, L.5    van Ree, R.6
  • 173
    • 33845430391 scopus 로고    scopus 로고
    • The impact of pollen-related food allergens on pollen allergy
    • Bohle, B., The impact of pollen-related food allergens on pollen allergy. Allergy 62:1 (2007), 3–10.
    • (2007) Allergy , vol.62 , Issue.1 , pp. 3-10
    • Bohle, B.1
  • 176
    • 26844540412 scopus 로고    scopus 로고
    • Prophylaxis and therapy of allergy by mucosal tolerance induction with recombinant allergens or allergen constructs
    • Wiedermann, U., Prophylaxis and therapy of allergy by mucosal tolerance induction with recombinant allergens or allergen constructs. Curr. Drug Targets Inflamm. Allergy 4:5 (2005), 577–583.
    • (2005) Curr. Drug Targets Inflamm. Allergy , vol.4 , Issue.5 , pp. 577-583
    • Wiedermann, U.1
  • 178
    • 0037449504 scopus 로고    scopus 로고
    • Suppression of allergen reactive Th2 mediated responses and pulmonary eosinophilia by intranasal administration of an immunodominant peptide is linked to IL-10 production
    • 5495–5461
    • Hall, G., Houghton, C.G., Rahbek, J.U., Lamb, J.R., Jarman, E.R., Suppression of allergen reactive Th2 mediated responses and pulmonary eosinophilia by intranasal administration of an immunodominant peptide is linked to IL-10 production. Vaccine, 21(5–6), 2003 5495–5461.
    • (2003) Vaccine , vol.21 , Issue.5-6
    • Hall, G.1    Houghton, C.G.2    Rahbek, J.U.3    Lamb, J.R.4    Jarman, E.R.5
  • 180
    • 0031871157 scopus 로고    scopus 로고
    • Hyposensitization to allergic reaction in rDer f 2-sensitized mice by the intranasal administration of a mutant of rDer f 2, C8/119S
    • Yasue, M., Yokota, T., Fukada, M., Takai, T., Suko, M., Okudaira, H., Okumura, Y., Hyposensitization to allergic reaction in rDer f 2-sensitized mice by the intranasal administration of a mutant of rDer f 2, C8/119S. Clin. Exp. Immunol. 113:1 (1998), 1–9.
    • (1998) Clin. Exp. Immunol. , vol.113 , Issue.1 , pp. 1-9
    • Yasue, M.1    Yokota, T.2    Fukada, M.3    Takai, T.4    Suko, M.5    Okudaira, H.6    Okumura, Y.7
  • 181
    • 0034665515 scopus 로고    scopus 로고
    • Inducing tolerance by intranasal administration of long peptides in naive and primed CBA/J mice
    • Astori, M., von Garnier, C., Kettner, A., Dufour, N., Corradin, G., Spertini, F., Inducing tolerance by intranasal administration of long peptides in naive and primed CBA/J mice. J. Immunol. 165:6 (2000), 3497–3505.
    • (2000) J. Immunol. , vol.165 , Issue.6 , pp. 3497-3505
    • Astori, M.1    von Garnier, C.2    Kettner, A.3    Dufour, N.4    Corradin, G.5    Spertini, F.6
  • 182
    • 84929484583 scopus 로고    scopus 로고
    • The role of alveolar epithelial type II-like cells in uptake of structurally different antigens and in polarisation of local immune responses
    • Akgun, J., Schabussova, I., Schwarzer, M., Kozakova, H., Kundi, M., Wiedermann, U., The role of alveolar epithelial type II-like cells in uptake of structurally different antigens and in polarisation of local immune responses. PLoS One, 10(4), 2015, e0124777.
    • (2015) PLoS One , vol.10 , Issue.4
    • Akgun, J.1    Schabussova, I.2    Schwarzer, M.3    Kozakova, H.4    Kundi, M.5    Wiedermann, U.6
  • 183
    • 0026046280 scopus 로고
    • Antigen-driven bystander suppression after oral administration of antigens
    • Miller, A., Lider, O., Weiner, H.L., Antigen-driven bystander suppression after oral administration of antigens. J. Exp. Med. 174:4 (1991), 791–798.
    • (1991) J. Exp. Med. , vol.174 , Issue.4 , pp. 791-798
    • Miller, A.1    Lider, O.2    Weiner, H.L.3
  • 184
    • 84919682478 scopus 로고    scopus 로고
    • Mechanisms of peptide immunotherapy in allergic airways disease
    • Larche, M., Mechanisms of peptide immunotherapy in allergic airways disease. Ann. Am. Thorac. Soc. 11:Suppl. 5 (2014), S292–296.
    • (2014) Ann. Am. Thorac. Soc. , vol.11 , pp. S292-296
    • Larche, M.1
  • 185
    • 84884241859 scopus 로고    scopus 로고
    • Cat peptide antigen desensitisation for treating cat allergic rhinoconjunctivitis
    • Worm, M., Patel, D., Creticos, P.S., Cat peptide antigen desensitisation for treating cat allergic rhinoconjunctivitis. Exp. Opin. Invest. Drugs 22:10 (2013), 1347–1357.
    • (2013) Exp. Opin. Invest. Drugs , vol.22 , Issue.10 , pp. 1347-1357
    • Worm, M.1    Patel, D.2    Creticos, P.S.3
  • 187
    • 0019161541 scopus 로고
    • Systemic tolerance and secretory immunity after oral immunization
    • Challacombe, S.J., Tomasi, T.B. Jr., Systemic tolerance and secretory immunity after oral immunization. J. Exp. Med. 152:6 (1980), 1459–1472.
    • (1980) J. Exp. Med. , vol.152 , Issue.6 , pp. 1459-1472
    • Challacombe, S.J.1    Tomasi, T.B.2
  • 190
    • 3142696286 scopus 로고    scopus 로고
    • Cholera toxin prevents Th1-mediated autoimmune disease by inducing immune deviation
    • Su, S.B., Silver, P.B., Wang, P., Chan, C.C., Caspi, R.R., Cholera toxin prevents Th1-mediated autoimmune disease by inducing immune deviation. J. Immunol. 173:2 (2004), 755–761.
    • (2004) J. Immunol. , vol.173 , Issue.2 , pp. 755-761
    • Su, S.B.1    Silver, P.B.2    Wang, P.3    Chan, C.C.4    Caspi, R.R.5
  • 191
    • 79956191499 scopus 로고    scopus 로고
    • An adjuvant free mouse model of oral allergenic sensitization to rice seeds protein
    • Chen, X.W., Lau, K.W., Yang, F., Sun, S.S., Fung, M.C., An adjuvant free mouse model of oral allergenic sensitization to rice seeds protein. BMC Gastroenterol., 11, 2011, 62.
    • (2011) BMC Gastroenterol. , vol.11 , pp. 62
    • Chen, X.W.1    Lau, K.W.2    Yang, F.3    Sun, S.S.4    Fung, M.C.5
  • 194
    • 70349929352 scopus 로고    scopus 로고
    • An adjuvant-free mouse model to evaluate the allergenicity of milk whey protein
    • Gonipeta, B., Parvataneni, S., Tempelman, R.J., Gangur, V., An adjuvant-free mouse model to evaluate the allergenicity of milk whey protein. J. Dairy Sci. 92:10 (2009), 4738–4744.
    • (2009) J. Dairy Sci. , vol.92 , Issue.10 , pp. 4738-4744
    • Gonipeta, B.1    Parvataneni, S.2    Tempelman, R.J.3    Gangur, V.4
  • 195
    • 76049095345 scopus 로고    scopus 로고
    • Long-term characteristics of hazelnut allergy in an adjuvant-free mouse model
    • Gonipeta, B., Parvataneni, S., Paruchuri, P., Gangur, V., Long-term characteristics of hazelnut allergy in an adjuvant-free mouse model. Int. Arch. Allergy Immunol. 152:3 (2010), 219–225.
    • (2010) Int. Arch. Allergy Immunol. , vol.152 , Issue.3 , pp. 219-225
    • Gonipeta, B.1    Parvataneni, S.2    Paruchuri, P.3    Gangur, V.4
  • 197
    • 84952646290 scopus 로고    scopus 로고
    • Current advances of murine models for food allergy
    • Liu, T., Navarro, S., Lopata, A.L., Current advances of murine models for food allergy. Mol. Immunol. 70 (2016), 104–117.
    • (2016) Mol. Immunol. , vol.70 , pp. 104-117
    • Liu, T.1    Navarro, S.2    Lopata, A.L.3
  • 198
    • 0038743007 scopus 로고    scopus 로고
    • Genetic susceptibility to food allergy is linked to differential TH2-TH1 responses in C3H/HeJ and BALB/c mice
    • Morafo, V., Srivastava, K., Huang, C.K., Kleiner, G., Lee, S.Y., Sampson, H.A., Li, A.M., Genetic susceptibility to food allergy is linked to differential TH2-TH1 responses in C3H/HeJ and BALB/c mice. J. Allergy Clin. Immunol. 111:5 (2003), 1122–1128.
    • (2003) J. Allergy Clin. Immunol. , vol.111 , Issue.5 , pp. 1122-1128
    • Morafo, V.1    Srivastava, K.2    Huang, C.K.3    Kleiner, G.4    Lee, S.Y.5    Sampson, H.A.6    Li, A.M.7
  • 199
    • 0032958073 scopus 로고    scopus 로고
    • Oral gene delivery with chitosan–DNA nanoparticles generates immunologic protection in a murine model of peanut allergy
    • Roy, K., Mao, H.Q., Huang, S.K., Leong, K.W., Oral gene delivery with chitosan–DNA nanoparticles generates immunologic protection in a murine model of peanut allergy. Nat. Med. 5:4 (1999), 387–391.
    • (1999) Nat. Med. , vol.5 , Issue.4 , pp. 387-391
    • Roy, K.1    Mao, H.Q.2    Huang, S.K.3    Leong, K.W.4
  • 201
    • 0033007557 scopus 로고    scopus 로고
    • Oral tolerance by a high dose OVA in BALB/c mice is more pronounced and persistent in Th2-mediated immune responses than in Th1 responses
    • Kang, B., Kim, K.M., Kang, C.Y., Oral tolerance by a high dose OVA in BALB/c mice is more pronounced and persistent in Th2-mediated immune responses than in Th1 responses. Immunobiology 200:2 (1999), 264–276.
    • (1999) Immunobiology , vol.200 , Issue.2 , pp. 264-276
    • Kang, B.1    Kim, K.M.2    Kang, C.Y.3
  • 202
    • 8144229304 scopus 로고    scopus 로고
    • A novel model of sensitization and oral tolerance to peanut protein
    • Strid, J., Thomson, M., Hourihane, J., Kimber, I., Strobel, S., A novel model of sensitization and oral tolerance to peanut protein. Immunology 113:3 (2004), 293–303.
    • (2004) Immunology , vol.113 , Issue.3 , pp. 293-303
    • Strid, J.1    Thomson, M.2    Hourihane, J.3    Kimber, I.4    Strobel, S.5
  • 204
    • 84907545938 scopus 로고    scopus 로고
    • Attenuation of allergic immune response phenotype by mannosylated egg white in orally induced allergy in BALB/c mice
    • Rupa, P., Nakamura, S., Katayama, S., Mine, Y., Attenuation of allergic immune response phenotype by mannosylated egg white in orally induced allergy in BALB/c mice. J. Agric. Food Chem. 62:39 (2014), 9479–9487.
    • (2014) J. Agric. Food Chem. , vol.62 , Issue.39 , pp. 9479-9487
    • Rupa, P.1    Nakamura, S.2    Katayama, S.3    Mine, Y.4
  • 206
    • 84959049763 scopus 로고    scopus 로고
    • T cell epitope immunotherapy ameliorates allergic responses in a murine model of shrimp allergy
    • Wai, C.Y., Leung, N.Y., Leung, P.S., Chu, K.H., T cell epitope immunotherapy ameliorates allergic responses in a murine model of shrimp allergy. Clin. Exp. Allergy 46:3 (2016), 491–503.
    • (2016) Clin. Exp. Allergy , vol.46 , Issue.3 , pp. 491-503
    • Wai, C.Y.1    Leung, N.Y.2    Leung, P.S.3    Chu, K.H.4
  • 207
    • 77949366819 scopus 로고    scopus 로고
    • Multiple T cell epitope peptides suppress allergic responses in an egg allergy mouse model by the elicitation of forkhead box transcription factor 3- and transforming growth factor-beta-associated mechanisms
    • Yang, M., Yang, C., Mine, Y., Multiple T cell epitope peptides suppress allergic responses in an egg allergy mouse model by the elicitation of forkhead box transcription factor 3- and transforming growth factor-beta-associated mechanisms. Clin. Exp. Allergy 40:4 (2010), 668–678.
    • (2010) Clin. Exp. Allergy , vol.40 , Issue.4 , pp. 668-678
    • Yang, M.1    Yang, C.2    Mine, Y.3
  • 208
    • 83555161730 scopus 로고    scopus 로고
    • Oral immunotherapy with immunodominant T-cell epitope peptides alleviates allergic reactions in a Balb/c mouse model of egg allergy
    • Rupa, P., Mine, Y., Oral immunotherapy with immunodominant T-cell epitope peptides alleviates allergic reactions in a Balb/c mouse model of egg allergy. Allergy 67:1 (2012), 74–82.
    • (2012) Allergy , vol.67 , Issue.1 , pp. 74-82
    • Rupa, P.1    Mine, Y.2
  • 210
    • 84997283005 scopus 로고    scopus 로고
    • Differences in phenotype, homing properties and suppressive activities of regulatory T cells induced by epicutaneous, oral or sublingual immunotherapy in mice sensitized to peanut
    • Dioszeghy, V., Mondoulet, L., Puteaux, E., Dhelft, V., Ligouis, M., Plaquet, C., Dupont, C., Benhamou, P.H., Differences in phenotype, homing properties and suppressive activities of regulatory T cells induced by epicutaneous, oral or sublingual immunotherapy in mice sensitized to peanut. Cell. Mol. Immunol. 13 (2016), 1–13.
    • (2016) Cell. Mol. Immunol. , vol.13 , pp. 1-13
    • Dioszeghy, V.1    Mondoulet, L.2    Puteaux, E.3    Dhelft, V.4    Ligouis, M.5    Plaquet, C.6    Dupont, C.7    Benhamou, P.H.8
  • 213
    • 84927646951 scopus 로고    scopus 로고
    • Cholera toxin, and the related nontoxic adjuvants mmCT and dmLT, promote human Th17 responses via cyclic AMP-protein kinase A and inflammasome-dependent IL-1 signaling
    • Larena, M., Holmgren, J., Lebens, M., Terrinoni, M., Lundgren, A., Cholera toxin, and the related nontoxic adjuvants mmCT and dmLT, promote human Th17 responses via cyclic AMP-protein kinase A and inflammasome-dependent IL-1 signaling. J. Immunol. 194:8 (2015), 3829–3839.
    • (2015) J. Immunol. , vol.194 , Issue.8 , pp. 3829-3839
    • Larena, M.1    Holmgren, J.2    Lebens, M.3    Terrinoni, M.4    Lundgren, A.5
  • 214
    • 77958195796 scopus 로고    scopus 로고
    • Mucosal adjuvants and long-term memory development with special focus on CTA1-DD and other ADP-ribosylating toxins
    • Lycke, N., Bemark, M., Mucosal adjuvants and long-term memory development with special focus on CTA1-DD and other ADP-ribosylating toxins. Mucosal Immunol. 3:6 (2010), 556–566.
    • (2010) Mucosal Immunol. , vol.3 , Issue.6 , pp. 556-566
    • Lycke, N.1    Bemark, M.2
  • 215
    • 79954535010 scopus 로고    scopus 로고
    • Characterization of a mutant Escherichia coli heat-labile toxin, LT(R192G/L211A), as a safe and effective oral adjuvant
    • Norton, E.B., Lawson, L.B., Freytag, L.C., Clements, J.D., Characterization of a mutant Escherichia coli heat-labile toxin, LT(R192G/L211A), as a safe and effective oral adjuvant. Clin. Vaccine Immunol. 18:4 (2011), 546–551.
    • (2011) Clin. Vaccine Immunol. , vol.18 , Issue.4 , pp. 546-551
    • Norton, E.B.1    Lawson, L.B.2    Freytag, L.C.3    Clements, J.D.4
  • 216
    • 0028007467 scopus 로고
    • Cholera toxin B subunit: an efficient transmucosal carrier-delivery system for induction of peripheral immunological tolerance
    • Sun, J.B., Holmgren, J., Czerkinsky, C., Cholera toxin B subunit: an efficient transmucosal carrier-delivery system for induction of peripheral immunological tolerance. Proc. Natl. Acad. Sci. U. S. A. 91:23 (1994), 10795–10799.
    • (1994) Proc. Natl. Acad. Sci. U. S. A. , vol.91 , Issue.23 , pp. 10795-10799
    • Sun, J.B.1    Holmgren, J.2    Czerkinsky, C.3
  • 217
    • 0043129198 scopus 로고    scopus 로고
    • Prolonged oral treatment with low doses of allergen conjugated to cholera toxin B subunit suppresses immunoglobulin E antibody responses in sensitized mice
    • Rask, C., Holmgren, J., Fredriksson, M., Lindblad, M., Nordström, I., Sun, J.B., Czerkinsky, C., Prolonged oral treatment with low doses of allergen conjugated to cholera toxin B subunit suppresses immunoglobulin E antibody responses in sensitized mice. Clin. Exp. Allergy 30:7 (2000), 1024–1032.
    • (2000) Clin. Exp. Allergy , vol.30 , Issue.7 , pp. 1024-1032
    • Rask, C.1    Holmgren, J.2    Fredriksson, M.3    Lindblad, M.4    Nordström, I.5    Sun, J.B.6    Czerkinsky, C.7
  • 218
    • 33747055056 scopus 로고    scopus 로고
    • Sublingual tolerance induction with antigen conjugated to cholera toxin B subunit induces foxp3 + CD25 + CD4+ regulatory T cells and suppresses delayed-type hypersensitivity reactions
    • Sun, J.B., Cuburu, N., Blomquist, M., Li, B.L., Czerkinsky, C., Holmgren, J., Sublingual tolerance induction with antigen conjugated to cholera toxin B subunit induces foxp3 + CD25 + CD4+ regulatory T cells and suppresses delayed-type hypersensitivity reactions. Scand. J. Immunol. 64:3 (2006), 251–259.
    • (2006) Scand. J. Immunol. , vol.64 , Issue.3 , pp. 251-259
    • Sun, J.B.1    Cuburu, N.2    Blomquist, M.3    Li, B.L.4    Czerkinsky, C.5    Holmgren, J.6
  • 219
    • 36248964723 scopus 로고    scopus 로고
    • Use of a genetic cholera toxin B subunit/allergen fusion molecule as mucosal delivery system with immunosuppressive activity against Th2 immune responses
    • Bublin, M., Hoflehner, E., Wagner, B., Radauer, C., Wagner, S., Hufnagl, K., Allwardt, D., Kundi, M., Scheiner, O., Wiedermann, U., Breiteneder, H., Use of a genetic cholera toxin B subunit/allergen fusion molecule as mucosal delivery system with immunosuppressive activity against Th2 immune responses. Vaccine 25:50 (2007), 8395–8404.
    • (2007) Vaccine , vol.25 , Issue.50 , pp. 8395-8404
    • Bublin, M.1    Hoflehner, E.2    Wagner, B.3    Radauer, C.4    Wagner, S.5    Hufnagl, K.6    Allwardt, D.7    Kundi, M.8    Scheiner, O.9    Wiedermann, U.10    Breiteneder, H.11
  • 220
    • 55049113863 scopus 로고    scopus 로고
    • Efficient induction of oral tolerance by fusing cholera toxin B subunit with allergen-specific T-cell epitopes accumulated in rice seed
    • Takagi, H., Hiroi, T., Yang, L., Takamura, K., Ishimitsu, R., Kawauchi, H., Takaiwa, F., Efficient induction of oral tolerance by fusing cholera toxin B subunit with allergen-specific T-cell epitopes accumulated in rice seed. Vaccine 26:48 (2008), 6027–6030.
    • (2008) Vaccine , vol.26 , Issue.48 , pp. 6027-6030
    • Takagi, H.1    Hiroi, T.2    Yang, L.3    Takamura, K.4    Ishimitsu, R.5    Kawauchi, H.6    Takaiwa, F.7
  • 221
    • 84942198700 scopus 로고    scopus 로고
    • Rice seed for delivery of vaccines to gut mucosal immune tissues
    • Takaiwa, F., Wakasa, Y., Takagi, H., Hiroi, T., Rice seed for delivery of vaccines to gut mucosal immune tissues. Plant Biotechnol. J. 13:8 (2015), 1041–1055.
    • (2015) Plant Biotechnol. J. , vol.13 , Issue.8 , pp. 1041-1055
    • Takaiwa, F.1    Wakasa, Y.2    Takagi, H.3    Hiroi, T.4
  • 223
    • 0031081395 scopus 로고    scopus 로고
    • Suppression of delayed-type hypersensitivity and IgE antibody responses to ovalbumin by intranasal administration of Escherichia coli heat-labile enterotoxin B subunit-conjugated ovalbumin
    • Tamura, S., Hatori, E., Tsuruhara, T., Aizawa, C., Kurata, T., Suppression of delayed-type hypersensitivity and IgE antibody responses to ovalbumin by intranasal administration of Escherichia coli heat-labile enterotoxin B subunit-conjugated ovalbumin. Vaccine 15:2 (1997), 225–229.
    • (1997) Vaccine , vol.15 , Issue.2 , pp. 225-229
    • Tamura, S.1    Hatori, E.2    Tsuruhara, T.3    Aizawa, C.4    Kurata, T.5
  • 224
    • 84898651732 scopus 로고    scopus 로고
    • Escherichia coli heat-labile detoxified enterotoxin modulates dendritic cell function and attenuates allergic airway inflammation
    • Lin, I.P., Hsu, Y.S., Kang, S.W., Hsieh, M.H., Wang, J.Y., Escherichia coli heat-labile detoxified enterotoxin modulates dendritic cell function and attenuates allergic airway inflammation. PLoS One, 9(3), 2014, e90293.
    • (2014) PLoS One , vol.9 , Issue.3 , pp. e90293
    • Lin, I.P.1    Hsu, Y.S.2    Kang, S.W.3    Hsieh, M.H.4    Wang, J.Y.5
  • 225
    • 9244246298 scopus 로고    scopus 로고
    • Toll-like receptor 9 can be expressed at the cell surface of distinct populations of tonsils and human peripheral blood mononuclear cells
    • Eaton-Bassiri, A., Dillon, S.B., Cunningham, M., Rycyzyn, M.A., Mills, J., Sarisky, R.T., Mbow, M.L., Toll-like receptor 9 can be expressed at the cell surface of distinct populations of tonsils and human peripheral blood mononuclear cells. Infect. Immun. 72:12 (2004), 7202–7211.
    • (2004) Infect. Immun. , vol.72 , Issue.12 , pp. 7202-7211
    • Eaton-Bassiri, A.1    Dillon, S.B.2    Cunningham, M.3    Rycyzyn, M.A.4    Mills, J.5    Sarisky, R.T.6    Mbow, M.L.7
  • 226
    • 36049014372 scopus 로고    scopus 로고
    • Effect of sublingual administration with a native or denatured protein allergen and adjuvant CpG oligodeoxynucleotides or cholera toxin on systemic T(H)2 immune responses and mucosal immunity in mice
    • Huang, C.F., Wang, C.C., Wu, T.C., Chu, C.H., Peng, H.J., Effect of sublingual administration with a native or denatured protein allergen and adjuvant CpG oligodeoxynucleotides or cholera toxin on systemic T(H)2 immune responses and mucosal immunity in mice. Ann. Allergy Asthma Immunol. 99:5 (2007), 443–452.
    • (2007) Ann. Allergy Asthma Immunol. , vol.99 , Issue.5 , pp. 443-452
    • Huang, C.F.1    Wang, C.C.2    Wu, T.C.3    Chu, C.H.4    Peng, H.J.5
  • 227
    • 53549101308 scopus 로고    scopus 로고
    • Effect of neonatal sublingual vaccination with native or denatured ovalbumin and adjuvant CpG or cholera toxin on systemic and mucosal immunity in mice
    • Huang, C.F., Wu, T.C., Chu, Y.H., Hwang, K.S., Wang, C.C., Peng, H.J., Effect of neonatal sublingual vaccination with native or denatured ovalbumin and adjuvant CpG or cholera toxin on systemic and mucosal immunity in mice. Scand. J. Immunol. 68:5 (2008), 502–510.
    • (2008) Scand. J. Immunol. , vol.68 , Issue.5 , pp. 502-510
    • Huang, C.F.1    Wu, T.C.2    Chu, Y.H.3    Hwang, K.S.4    Wang, C.C.5    Peng, H.J.6
  • 228
    • 33644856095 scopus 로고    scopus 로고
    • Oral administration of CpG-ODNs suppresses antigen-induced asthma in mice
    • Kitagaki, K., Businga, T.R., Kline, J.N., Oral administration of CpG-ODNs suppresses antigen-induced asthma in mice. Clin. Exp. Immunol. 143:2 (2006), 249–259.
    • (2006) Clin. Exp. Immunol. , vol.143 , Issue.2 , pp. 249-259
    • Kitagaki, K.1    Businga, T.R.2    Kline, J.N.3
  • 231
    • 0033563211 scopus 로고    scopus 로고
    • Long term prevention of allergic lung inflammation in a mouse model of asthma by CpG oligodeoxynucleotides
    • Sur, S., Wild, J.S., Choudhury, B.K., Sur, N., Alam, R., Klinman, D.M., Long term prevention of allergic lung inflammation in a mouse model of asthma by CpG oligodeoxynucleotides. J. Immunol. 162:10 (1999), 6284–6293.
    • (1999) J. Immunol. , vol.162 , Issue.10 , pp. 6284-6293
    • Sur, S.1    Wild, J.S.2    Choudhury, B.K.3    Sur, N.4    Alam, R.5    Klinman, D.M.6
  • 232
    • 84901243043 scopus 로고    scopus 로고
    • A limited CpG-containing oligodeoxynucleotide therapy regimen induces sustained suppression of allergic airway inflammation in mice
    • Campbell, J.D., Kell, S.A., Kozy, H.M., Lum, J.A., A limited CpG-containing oligodeoxynucleotide therapy regimen induces sustained suppression of allergic airway inflammation in mice. Thorax 69:6 (2015), 565–573.
    • (2015) Thorax , vol.69 , Issue.6 , pp. 565-573
    • Campbell, J.D.1    Kell, S.A.2    Kozy, H.M.3    Lum, J.A.4
  • 233
    • 33748920925 scopus 로고    scopus 로고
    • The structure and synthesis of the fungal cell wall
    • Bowman, S.M., Free, S.J., The structure and synthesis of the fungal cell wall. Bioessays 28:8 (2006), 799–808.
    • (2006) Bioessays , vol.28 , Issue.8 , pp. 799-808
    • Bowman, S.M.1    Free, S.J.2
  • 234
    • 84875071074 scopus 로고    scopus 로고
    • Innate sensing of chitin and chitosan
    • Bueter, C.L., Specht, C.A., Levitz, S.M., Innate sensing of chitin and chitosan. PLoS Pathog., 9(1), 2013, e1003080.
    • (2013) PLoS Pathog. , vol.9 , Issue.1 , pp. e1003080
    • Bueter, C.L.1    Specht, C.A.2    Levitz, S.M.3
  • 235
    • 0034142181 scopus 로고    scopus 로고
    • Oral administration of chitin down-regulates serum IgE levels and lung eosinophilia in the allergic mouse
    • Shibata, Y., Foster, L.A., Bradfield, J.F., Myrvik, Q.N., Oral administration of chitin down-regulates serum IgE levels and lung eosinophilia in the allergic mouse. J. Immunol. 164:3 (2000), 1314–1321.
    • (2000) J. Immunol. , vol.164 , Issue.3 , pp. 1314-1321
    • Shibata, Y.1    Foster, L.A.2    Bradfield, J.F.3    Myrvik, Q.N.4
  • 236
    • 0036456464 scopus 로고    scopus 로고
    • Intranasal application of chitin microparticles down-regulates symptoms of allergic hypersensitivity to Dermatophagoides pteronyssinus and Aspergillus fumigatus in murine models of allergy
    • Strong, P., Clark, H., Reid, K., Intranasal application of chitin microparticles down-regulates symptoms of allergic hypersensitivity to Dermatophagoides pteronyssinus and Aspergillus fumigatus in murine models of allergy. Clin. Exp. Allergy 32:12 (2002), 1794–1800.
    • (2002) Clin. Exp. Allergy , vol.32 , Issue.12 , pp. 1794-1800
    • Strong, P.1    Clark, H.2    Reid, K.3
  • 238
    • 62749191275 scopus 로고    scopus 로고
    • Chitin, chitinases and chitinase-like proteins in allergic inflammation and tissue remodeling
    • Lee, C.G., Chitin, chitinases and chitinase-like proteins in allergic inflammation and tissue remodeling. Yonsei Med. J. 50:1 (2009), 22–30.
    • (2009) Yonsei Med. J. , vol.50 , Issue.1 , pp. 22-30
    • Lee, C.G.1
  • 239
    • 84959045203 scopus 로고    scopus 로고
    • Polymer-lipid hybrid systems: merging the benefits of polymeric and lipid-based nanocarriers to improve oral drug delivery
    • Rao, S., Prestidge, C.A., Polymer-lipid hybrid systems: merging the benefits of polymeric and lipid-based nanocarriers to improve oral drug delivery. Exp. Opin. Drug Deliv. 13:5 (2016), 691–707.
    • (2016) Exp. Opin. Drug Deliv. , vol.13 , Issue.5 , pp. 691-707
    • Rao, S.1    Prestidge, C.A.2
  • 240
    • 84957588039 scopus 로고    scopus 로고
    • Preparation characterization, and potential application of chitosan, chitosan derivatives, and chitosan metal nanoparticles in pharmaceutical drug delivery
    • Ahmed, T.A., Aljaeid, B.M., Preparation characterization, and potential application of chitosan, chitosan derivatives, and chitosan metal nanoparticles in pharmaceutical drug delivery. Drug Des. Dev. Ther. 10 (2016), 483–507.
    • (2016) Drug Des. Dev. Ther. , vol.10 , pp. 483-507
    • Ahmed, T.A.1    Aljaeid, B.M.2
  • 241
    • 40149105232 scopus 로고    scopus 로고
    • The effect of water-soluble chitosan on macrophage activation and the attenuation of mite allergen-induced airway inflammation
    • Chen, C.L., Wang, Y.M., Liu, C.F., Wang, J.Y., The effect of water-soluble chitosan on macrophage activation and the attenuation of mite allergen-induced airway inflammation. Biomaterials 29:14 (2008), 2173–2182.
    • (2008) Biomaterials , vol.29 , Issue.14 , pp. 2173-2182
    • Chen, C.L.1    Wang, Y.M.2    Liu, C.F.3    Wang, J.Y.4
  • 242
    • 66149103652 scopus 로고    scopus 로고
    • Local nasal immunotherapy: efficacy of dermatophagoides farinae-chitosan vaccine in murine asthma
    • Liu, Z., Guo, H., Wu, Y., Yu, H., Yang, H., Li, J., Local nasal immunotherapy: efficacy of dermatophagoides farinae-chitosan vaccine in murine asthma. Int. Arch. Allergy Immunol. 150:3 (2009), 221–228.
    • (2009) Int. Arch. Allergy Immunol. , vol.150 , Issue.3 , pp. 221-228
    • Liu, Z.1    Guo, H.2    Wu, Y.3    Yu, H.4    Yang, H.5    Li, J.6
  • 244
    • 0038513487 scopus 로고    scopus 로고
    • Chitosan nanoparticles containing plasmid DNA encoding house dust mite allergen, Der p 1 for oral vaccination in mice
    • Chew, J., Wolfowicz, C., Mao, H., Leong, K., Chua, K., Chitosan nanoparticles containing plasmid DNA encoding house dust mite allergen, Der p 1 for oral vaccination in mice. Vaccine 21:21–22 (2003), 2720–2729.
    • (2003) Vaccine , vol.21 , Issue.21-22 , pp. 2720-2729
    • Chew, J.1    Wolfowicz, C.2    Mao, H.3    Leong, K.4    Chua, K.5
  • 245
    • 65549110410 scopus 로고    scopus 로고
    • Induction of Th1-type immune response by chitosan nanoparticles containing plasmid DNA encoding house dust mite allergen Der p 2 for oral vaccination in mice
    • Li, G.P., Liu, Z.G., Liao, B., Zhong, N.S., Induction of Th1-type immune response by chitosan nanoparticles containing plasmid DNA encoding house dust mite allergen Der p 2 for oral vaccination in mice. Cell. Mol. Immunol. 6:1 (2009), 45–50.
    • (2009) Cell. Mol. Immunol. , vol.6 , Issue.1 , pp. 45-50
    • Li, G.P.1    Liu, Z.G.2    Liao, B.3    Zhong, N.S.4
  • 246
    • 84871750316 scopus 로고    scopus 로고
    • The influence of commensal bacteria-derived signals on basophil-associated allergic inflammation
    • Hill, D.A., Artis, D., The influence of commensal bacteria-derived signals on basophil-associated allergic inflammation. Gut Microbes 4:1 (2013), 76–83.
    • (2013) Gut Microbes , vol.4 , Issue.1 , pp. 76-83
    • Hill, D.A.1    Artis, D.2
  • 247
    • 0031571230 scopus 로고    scopus 로고
    • The requirement of intestinal bacterial flora for the development of an IgE production system fully susceptible to oral tolerance induction
    • Sudo, N., Sawamura, S., Tanaka, K., Aiba, Y., Kubo, C., Koga, Y., The requirement of intestinal bacterial flora for the development of an IgE production system fully susceptible to oral tolerance induction. J. Immunol. 159:4 (1997), 1739–1745.
    • (1997) J. Immunol. , vol.159 , Issue.4 , pp. 1739-1745
    • Sudo, N.1    Sawamura, S.2    Tanaka, K.3    Aiba, Y.4    Kubo, C.5    Koga, Y.6
  • 248
    • 0035987318 scopus 로고    scopus 로고
    • An oral introduction of intestinal bacteria prevents the development of a long-term Th2-skewed immunological memory induced by neonatal antibiotic treatment in mice
    • Sudo, N., Yu, X.N., Aiba, Y., Oyama, N., Sonoda, J., Koga, Y., Kubo, C., An oral introduction of intestinal bacteria prevents the development of a long-term Th2-skewed immunological memory induced by neonatal antibiotic treatment in mice. Clin. Exp. Allergy 32:7 (2002), 1112–1116.
    • (2002) Clin. Exp. Allergy , vol.32 , Issue.7 , pp. 1112-1116
    • Sudo, N.1    Yu, X.N.2    Aiba, Y.3    Oyama, N.4    Sonoda, J.5    Koga, Y.6    Kubo, C.7
  • 249
    • 0035141642 scopus 로고    scopus 로고
    • Antibiotic use during infancy promotes a shift in the T(H)1/T(H)2 balance toward T(H)2-dominant immunity in mice
    • Oyama, N., Sudo, N., Sogawa, H., Kubo, C., Antibiotic use during infancy promotes a shift in the T(H)1/T(H)2 balance toward T(H)2-dominant immunity in mice. J. Allergy Clin. Immunol. 107:1 (2001), 153–159.
    • (2001) J. Allergy Clin. Immunol. , vol.107 , Issue.1 , pp. 153-159
    • Oyama, N.1    Sudo, N.2    Sogawa, H.3    Kubo, C.4
  • 252
    • 85012060415 scopus 로고    scopus 로고
    • Post-sensitization administration of non-digestible oligosaccharides and Bifidobacterium breve M-16V reduces allergic symptoms in mice
    • van Esch, B.C.A.M., Abbring, S., Diks, M.A.P., Dingjan, G.M., Harthoorn, L.F., Vos, A.P., Garssen, J., Post-sensitization administration of non-digestible oligosaccharides and Bifidobacterium breve M-16V reduces allergic symptoms in mice. Immun. Inflamm. Dis. 4:2 (2016), 155–165.
    • (2016) Immun. Inflamm. Dis. , vol.4 , Issue.2 , pp. 155-165
    • van Esch, B.C.A.M.1    Abbring, S.2    Diks, M.A.P.3    Dingjan, G.M.4    Harthoorn, L.F.5    Vos, A.P.6    Garssen, J.7
  • 254
    • 84886099820 scopus 로고    scopus 로고
    • Neonatal colonization of germ-free mice with Bifidobacterium longum prevents allergic sensitization to major birch pollen allergen Bet v 1
    • Schwarzer, M., Srutkova, D., Schabussova, I., Hudcovic, T., Akgün, J., Wiedermann, U., Kozakova, H., Neonatal colonization of germ-free mice with Bifidobacterium longum prevents allergic sensitization to major birch pollen allergen Bet v 1. Vaccine 31:46 (2013), 5405–5412.
    • (2013) Vaccine , vol.31 , Issue.46 , pp. 5405-5412
    • Schwarzer, M.1    Srutkova, D.2    Schabussova, I.3    Hudcovic, T.4    Akgün, J.5    Wiedermann, U.6    Kozakova, H.7
  • 257
    • 79951723669 scopus 로고    scopus 로고
    • Distinctive anti-allergy properties of two probiotic bacterial strains in a mouse model of allergic poly-sensitization
    • Schabussova, I., Hufnagl, K., Wild, C., Nutten, S., Zuercher, A.W., Mercenier, A., Wiedermann, U., Distinctive anti-allergy properties of two probiotic bacterial strains in a mouse model of allergic poly-sensitization. Vaccine 29:10 (2011), 1981–1990.
    • (2011) Vaccine , vol.29 , Issue.10 , pp. 1981-1990
    • Schabussova, I.1    Hufnagl, K.2    Wild, C.3    Nutten, S.4    Zuercher, A.W.5    Mercenier, A.6    Wiedermann, U.7
  • 258
    • 33745139808 scopus 로고    scopus 로고
    • Modulation of allergic immune responses by mucosal application of recombinant lactic acid bacteria producing the major birch pollen allergen Bet v 1
    • Daniel, C., Repa, A., Wild, C., Pollak, A., Pot, B., Breiteneder, H., Wiedermann, U., Mercenier, A., Modulation of allergic immune responses by mucosal application of recombinant lactic acid bacteria producing the major birch pollen allergen Bet v 1. Allergy 61:7 (2006), 812–819.
    • (2006) Allergy , vol.61 , Issue.7 , pp. 812-819
    • Daniel, C.1    Repa, A.2    Wild, C.3    Pollak, A.4    Pot, B.5    Breiteneder, H.6    Wiedermann, U.7    Mercenier, A.8
  • 260
    • 35148876533 scopus 로고    scopus 로고
    • The European LABDEL project and its relevance to the prevention and treatment of allergies
    • Daniel, C., Repa, A., Mercenier, A., Wiedermann, U., Wells, J., The European LABDEL project and its relevance to the prevention and treatment of allergies. Allergy 62:11 (2007), 1237–1242.
    • (2007) Allergy , vol.62 , Issue.11 , pp. 1237-1242
    • Daniel, C.1    Repa, A.2    Mercenier, A.3    Wiedermann, U.4    Wells, J.5
  • 262
    • 34047124665 scopus 로고    scopus 로고
    • Oral administration of an IL-10-secreting Lactococcus lactis strain prevents food-induced IgE sensitization
    • Frossard, C.P., Steidler, L., Eigenmann, P.A., Oral administration of an IL-10-secreting Lactococcus lactis strain prevents food-induced IgE sensitization. J. Allergy Clin. Immunol. 119:4 (2007), 952–959.
    • (2007) J. Allergy Clin. Immunol. , vol.119 , Issue.4 , pp. 952-959
    • Frossard, C.P.1    Steidler, L.2    Eigenmann, P.A.3
  • 264
    • 84994499806 scopus 로고    scopus 로고
    • Balancing tolerance or allergy to food proteins
    • Bryce, P.J., Balancing tolerance or allergy to food proteins. Trends Immunol. 37:10 (2016), 659–667.
    • (2016) Trends Immunol. , vol.37 , Issue.10 , pp. 659-667
    • Bryce, P.J.1
  • 265
    • 84973438720 scopus 로고    scopus 로고
    • Parasitic helminth infections and the control of human allergic and autoimmune disorders
    • Maizels, R.M., Parasitic helminth infections and the control of human allergic and autoimmune disorders. Clin. Microbiol. Infect. 22:6 (2016), 481–486.
    • (2016) Clin. Microbiol. Infect. , vol.22 , Issue.6 , pp. 481-486
    • Maizels, R.M.1
  • 266
    • 0037105415 scopus 로고    scopus 로고
    • An enteric helminth infection protects against an allergic response to dietary antigen
    • Bashir, M.E.H., Andersen, P., Fuss, I.J., Shi, H.N., Nagler-Anderson, C., An enteric helminth infection protects against an allergic response to dietary antigen. J. Immunol. 169:6 (2002), 3284–3292.
    • (2002) J. Immunol. , vol.169 , Issue.6 , pp. 3284-3292
    • Bashir, M.E.H.1    Andersen, P.2    Fuss, I.J.3    Shi, H.N.4    Nagler-Anderson, C.5
  • 267
    • 0035725696 scopus 로고    scopus 로고
    • Infection of mice with the helminth Strongyloides stercoralis suppresses pulmonary allergic responses to ovalbumin
    • Wang, C.C., Nolan, T.J., Schad, G.A., Abraham, D., Infection of mice with the helminth Strongyloides stercoralis suppresses pulmonary allergic responses to ovalbumin. Clin. Exp. Allergy 31:3 (2001), 495–503.
    • (2001) Clin. Exp. Allergy , vol.31 , Issue.3 , pp. 495-503
    • Wang, C.C.1    Nolan, T.J.2    Schad, G.A.3    Abraham, D.4
  • 268
    • 1842843826 scopus 로고    scopus 로고
    • Helminth infection modulates the development of allergen-induced airway inflammation
    • Wohlleben, G., Trujillo, C., Muller, J., Ritze, Y., Grunewald, S., Tatsch, U., Erb, K.J., Helminth infection modulates the development of allergen-induced airway inflammation. Int. Immunol. 16:4 (2004), 585–596.
    • (2004) Int. Immunol. , vol.16 , Issue.4 , pp. 585-596
    • Wohlleben, G.1    Trujillo, C.2    Muller, J.3    Ritze, Y.4    Grunewald, S.5    Tatsch, U.6    Erb, K.J.7
  • 270
    • 85013941725 scopus 로고    scopus 로고
    • Oocyst-derived extract of Toxoplasma gondii serves as potent immunomodulator in a mouse model of birch pollen allergy
    • Wagner, A., Schabussova, I., Drinic, M., Akgun, J., Loupal, G., Kundi, M., Joachim, A., Wiedermann, U., Oocyst-derived extract of Toxoplasma gondii serves as potent immunomodulator in a mouse model of birch pollen allergy. PLoS One, 11(5), 2016, e0155081.
    • (2016) PLoS One , vol.11 , Issue.5 , pp. e0155081
    • Wagner, A.1    Schabussova, I.2    Drinic, M.3    Akgun, J.4    Loupal, G.5    Kundi, M.6    Joachim, A.7    Wiedermann, U.8
  • 271
    • 84879774160 scopus 로고    scopus 로고
    • Oesophagostomum dentatum extract modulates T cell-dependent immune responses to bystander antigens and prevents the development of allergy in mice
    • Schabussova, I., Ul-Haq, O., Hoflehner, E., Akgun, J., Wagner, A., Loupal, G., Joachim, A., Ruttkowski, B., Maizels, R.M., Wiedermann, U., Oesophagostomum dentatum extract modulates T cell-dependent immune responses to bystander antigens and prevents the development of allergy in mice. PLoS One, 8(7), 2013, e67544.
    • (2013) PLoS One , vol.8 , Issue.7 , pp. e67544
    • Schabussova, I.1    Ul-Haq, O.2    Hoflehner, E.3    Akgun, J.4    Wagner, A.5    Loupal, G.6    Joachim, A.7    Ruttkowski, B.8    Maizels, R.M.9    Wiedermann, U.10
  • 274
    • 84865425687 scopus 로고    scopus 로고
    • Heligmosomoides polygyrus bakeri induces tolerogenic dendritic cells that block colitis and prevent antigen-specific gut T cell responses
    • Blum, A.M., Hang, L., Setiawan, T., Urban, J.P., Stoyanoff, K.M., Leung, J., Weinstock, J.V., Heligmosomoides polygyrus bakeri induces tolerogenic dendritic cells that block colitis and prevent antigen-specific gut T cell responses. J. Immunol. 189:5 (2012), 2512–2520.
    • (2012) J. Immunol. , vol.189 , Issue.5 , pp. 2512-2520
    • Blum, A.M.1    Hang, L.2    Setiawan, T.3    Urban, J.P.4    Stoyanoff, K.M.5    Leung, J.6    Weinstock, J.V.7
  • 275
    • 84957612502 scopus 로고    scopus 로고
    • Low-dose intestinal Trichuris muris infection alters the lung immune microenvironment and can suppress allergic airway inflammation
    • Chenery, A.L., Antignano, F., Burrows, K., Scheer, S., Perona-Wright, G., Zaph, C., Low-dose intestinal Trichuris muris infection alters the lung immune microenvironment and can suppress allergic airway inflammation. Infect. Immun. 84:2 (2015), 491–501.
    • (2015) Infect. Immun. , vol.84 , Issue.2 , pp. 491-501
    • Chenery, A.L.1    Antignano, F.2    Burrows, K.3    Scheer, S.4    Perona-Wright, G.5    Zaph, C.6
  • 276
    • 84904241397 scopus 로고    scopus 로고
    • Blockade of IL-33 release and suppression of type 2 innate lymphoid cell responses by helminth secreted products in airway allergy
    • McSorley, H.J., Blair, N.F., Smith, K.A., McKenzie, A.N., Maizels, R.M., Blockade of IL-33 release and suppression of type 2 innate lymphoid cell responses by helminth secreted products in airway allergy. Mucosal Immunol. 7:5 (2014), 1068–1078.
    • (2014) Mucosal Immunol. , vol.7 , Issue.5 , pp. 1068-1078
    • McSorley, H.J.1    Blair, N.F.2    Smith, K.A.3    McKenzie, A.N.4    Maizels, R.M.5
  • 277
    • 84920587175 scopus 로고    scopus 로고
    • Gut microbiota and allergy: the importance of the pregnancy period
    • Abrahamsson, T.R., Wu, R.Y., Jenmalm, M.C., Gut microbiota and allergy: the importance of the pregnancy period. Pediatr. Res. 77:1–2 (2015), 214–219.
    • (2015) Pediatr. Res. , vol.77 , Issue.1-2 , pp. 214-219
    • Abrahamsson, T.R.1    Wu, R.Y.2    Jenmalm, M.C.3


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