메뉴 건너뛰기




Volumn 30, Issue 7, 2000, Pages 1024-1032

Prolonged oral treatment with low doses of allergen conjugated to cholera toxin B subunit suppresses immunoglobulin E antibody responses in sensitized mice

Author keywords

Allergy; Cholera toxin B subunit; Immunoglobulin E; Immunotherapy; Oral tolerance; Ovalbumin

Indexed keywords

ALLERGEN; CHOLERA TOXIN B SUBUNIT; IMMUNOGLOBULIN E ANTIBODY; IMMUNOGLOBULIN G ANTIBODY; OVALBUMIN;

EID: 0043129198     PISSN: 09547894     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2222.2000.00849.x     Document Type: Article
Times cited : (61)

References (56)
  • 1
    • 84951657129 scopus 로고
    • Studies on the chemistry of anaphylaxis III. Experiments with isolated proteins, especially those of hen's egg
    • 1 Wells H. Studies on the chemistry of anaphylaxis III. Experiments with isolated proteins, especially those of hen's egg. J Infect Dis 1911; 9:147-71.
    • (1911) J Infect Dis , vol.9 , pp. 147-171
    • Wells, H.1
  • 2
    • 84939314060 scopus 로고
    • Inhibition of experimental drug allergy by prior feeding of the sensitizing agent
    • 2 Chase MW. Inhibition of experimental drug allergy by prior feeding of the sensitizing agent. Proc Soc Exp Biol 1946; 61:257-9.
    • (1946) Proc Soc Exp Biol , vol.61 , pp. 257-259
    • Chase, M.W.1
  • 3
    • 0019958195 scopus 로고
    • Clinical and immunological responses to oral and subcutaneous immunotherapy with grass pollen extracts
    • 3 Rebien W, Puttonen E, Maasch HJ, Stix E, Wahn U. Clinical and immunological responses to oral and subcutaneous immunotherapy with grass pollen extracts. Eur J Pediatr 1982; 138:341-4.
    • (1982) Eur J Pediatr , vol.138 , pp. 341-344
    • Rebien, W.1    Puttonen, E.2    Maasch, H.J.3    Stix, E.4    Wahn, U.5
  • 4
    • 0017656968 scopus 로고
    • Oral hyposensitization of children with pollinosis or house dust asthma
    • 4 Wortmann F. Oral hyposensitization of children with pollinosis or house dust asthma. Allergol Immunopathol 1977; 5:15-26.
    • (1977) Allergol Immunopathol , vol.5 , pp. 15-26
    • Wortmann, F.1
  • 5
    • 0031571738 scopus 로고    scopus 로고
    • Regulation of antigen-specific IgE, IgG1, and mast cell responses to ingested allergen by mucosal tolerance induction
    • 5 van Halteren AG, van der Cammen MJ, Cooper D, Savelkoul DF, Kraal G, Holt PG. Regulation of antigen-specific IgE, IgG1, and mast cell responses to ingested allergen by mucosal tolerance induction. J Immunol 1997; 159:3009-15.
    • (1997) J Immunol , vol.159 , pp. 3009-3015
    • Van Halteren, A.G.1    Van Der Cammen, M.J.2    Cooper, D.3    Savelkoul, D.F.4    Kraal, G.5    Holt, P.G.6
  • 7
    • 0024524088 scopus 로고
    • Suppression of experimental autoimmune encephalomyelitis by oral administration of myelin basic protein
    • 7 Lider D, Santos LLMB, Lee CSY, Higgins PJ, Weiner HL. Suppression of experimental autoimmune encephalomyelitis by oral administration of myelin basic protein. J Immunol 1989; 142:748-52.
    • (1989) J Immunol , vol.142 , pp. 748-752
    • Lider, D.1    Santos, L.L.M.B.2    Lee, C.S.Y.3    Higgins, P.J.4    Weiner, H.L.5
  • 8
    • 0025347507 scopus 로고
    • Inhibition of S-antigen induced experimental autoimmune uveoretinitis by oral induction of tolerance with S-antigen
    • 8 Nussenblatt RB, Caspi RR, Mahdi R, Chan CC, Roberge F, Lider O, Weiner HL. Inhibition of S-antigen induced experimental autoimmune uveoretinitis by oral induction of tolerance with S-antigen. J Immunol 1990; 144:1689-95.
    • (1990) J Immunol , vol.144 , pp. 1689-1695
    • Nussenblatt, R.B.1    Caspi, R.R.2    Mahdi, R.3    Chan, C.C.4    Roberge, F.5    Lider, O.6    Weiner, H.L.7
  • 9
    • 0027271837 scopus 로고
    • Suppression of experimental autoimmune myasthenia gravis by oral administration of acetylcholine receptor
    • 9 Wang ZY, Qiao J, Link H. Suppression of experimental autoimmune myasthenia gravis by oral administration of acetylcholine receptor. J Neuroimmunol 1993; 44:209-14.
    • (1993) J Neuroimmunol , vol.44 , pp. 209-214
    • Wang, Z.Y.1    Qiao, J.2    Link, H.3
  • 10
    • 0023927111 scopus 로고
    • Suppression of experimental autoimmune encephalomyelitis by the oral administration of myelin basic protein
    • 10 Bitar DM, Whitacre CC. Suppression of experimental autoimmune encephalomyelitis by the oral administration of myelin basic protein. Cell Immunol 1988; 112:364-70.
    • (1988) Cell Immunol , vol.112 , pp. 364-370
    • Bitar, D.M.1    Whitacre, C.C.2
  • 11
  • 12
    • 0028358048 scopus 로고
    • Induction of anergy or active suppression following oral tolerance is determined by antigen dosage
    • 12 Friedman A, Weiner HL. Induction of anergy or active suppression following oral tolerance is determined by antigen dosage. Proc Natl Acad Sci USA 1994; 91:6688-92.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 6688-6692
    • Friedman, A.1    Weiner, H.L.2
  • 13
    • 0030043855 scopus 로고    scopus 로고
    • Oral tolerance in myelin basic protein T-cell receptor transgenic mice: Suppression of autoimmune encephalomyelitis and dose-dependent induction of regulatory cells
    • 13 Chen Y, Inobe JI, Kuchroo VK, Baron JL, Janeway CA, Jr Weiner HL. Oral tolerance in myelin basic protein T-cell receptor transgenic mice: Suppression of autoimmune encephalomyelitis and dose-dependent induction of regulatory cells. Proc Natl Acad Sci USA 1996; 93:388-91.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 388-391
    • Chen, Y.1    Inobe, J.I.2    Kuchroo, V.K.3    Baron, J.L.4    Janeway, C.A.5    Weiner H.L., Jr.6
  • 14
    • 0031716664 scopus 로고    scopus 로고
    • IL-4 is a differentiation factor for transforming growth factor-β secreting Th3 cells and oral administration of IL-4 enhances oral tolerance in experimental allergic encephalomyelitis
    • 14 Inobr JI, Slavin AJ, Komagata Y, Chen Y, Liu L, Weiner HL. IL-4 is a differentiation factor for transforming growth factor-β secreting Th3 cells and oral administration of IL-4 enhances oral tolerance in experimental allergic encephalomyelitis. Eur J Immunol 1998; 28:2780-90.
    • (1998) Eur J Immunol , vol.28 , pp. 2780-2790
    • Inobr, J.I.1    Slavin, A.J.2    Komagata, Y.3    Chen, Y.4    Liu, L.5    Weiner, H.L.6
  • 15
    • 0021165561 scopus 로고
    • Cholera toxin B subunit as a carrier protein to stimulate a mucosal immune response
    • 15 McKenzie SJ, Halsey JF. Cholera toxin B subunit as a carrier protein to stimulate a mucosal immune response. J Immunol 1984; 133:1818-24.
    • (1984) J Immunol , vol.133 , pp. 1818-1824
    • McKenzie, S.J.1    Halsey, J.F.2
  • 16
    • 0023854852 scopus 로고
    • Oral vaccination: Identification of classes of proteins that provoke immune response upon oral feeding
    • 16 de Aizpura HJ, Russel-Jones GJ. Oral vaccination: Identification of classes of proteins that provoke immune response upon oral feeding. J Exp Med 1988; 167:440-51.
    • (1988) J Exp Med , vol.167 , pp. 440-451
    • De Aizpura, H.J.1    Russel-Jones, G.J.2
  • 17
    • 0024565465 scopus 로고
    • Oral administration of a streptococcal antigen coupled to cholera toxin B subunit evokes strong antibody responses in salivary glands and extramucosal tissues
    • 17 Czerkinsky C, Russel MW, Lycke N, Lindblad M, Holmgren J. Oral administration of a streptococcal antigen coupled to cholera toxin B subunit evokes strong antibody responses in salivary glands and extramucosal tissues. Inf Imm 1989; 57:1072-7.
    • (1989) Inf Imm , vol.57 , pp. 1072-1077
    • Czerkinsky, C.1    Russel, M.W.2    Lycke, N.3    Lindblad, M.4    Holmgren, J.5
  • 18
    • 0027486404 scopus 로고
    • Cholera toxin and cholera B subunit as oral - Mucosal adjuvant and antigen vector systems
    • 18 Holmgren J, Lycke N, Czerkinsky C. Cholera toxin and cholera B subunit as oral - mucosal adjuvant and antigen vector systems. Vaccine 1993; 11:1179-84.
    • (1993) Vaccine , vol.11 , pp. 1179-1184
    • Holmgren, J.1    Lycke, N.2    Czerkinsky, C.3
  • 19
    • 0028927443 scopus 로고
    • Local and systemic antibody responses to dextran-cholera toxin B subunit conjugates
    • 19 Bergquist C, Lagergård T, Lindblad M, Holmgren J. Local and systemic antibody responses to dextran-cholera toxin B subunit conjugates. Inf Imm 1995; 63:2021-5.
    • (1995) Inf Imm , vol.63 , pp. 2021-2025
    • Bergquist, C.1    Lagergård, T.2    Lindblad, M.3    Holmgren, J.4
  • 20
    • 0028007467 scopus 로고
    • Cholera toxin B subunit: An efficient transmucosal carrier-delivery system for induction of peripheral immunological tolerance
    • 20 Sun JB, Holmgren J, Czerkinsky C. Cholera toxin B subunit: an efficient transmucosal carrier-delivery system for induction of peripheral immunological tolerance. Proc Natl Acad Sci USA 1994; 91:10795-9.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 10795-10799
    • Sun, J.B.1    Holmgren, J.2    Czerkinsky, C.3
  • 21
    • 0029900868 scopus 로고    scopus 로고
    • Treatment of experimental autoimmune encephalomyelitis by feeding myelin basic protein conjugated to cholera toxin B subunit
    • 21 Sun JB, Rask C, Olsson T, Holmgren J, Czerkinsky C. Treatment of experimental autoimmune encephalomyelitis by feeding myelin basic protein conjugated to cholera toxin B subunit. Proc Natl Acad Sci USA 1996; 93:7196-201.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 7196-7201
    • Sun, J.B.1    Rask, C.2    Olsson, T.3    Holmgren, J.4    Czerkinsky, C.5
  • 23
    • 0019161541 scopus 로고
    • Systemic tolerance and secretory immunity after oral immunization
    • 23 Challacombe SJ, Tomasi TB. Systemic tolerance and secretory immunity after oral immunization. J Exp Med 1980; 152:1459-72.
    • (1980) J Exp Med , vol.152 , pp. 1459-1472
    • Challacombe, S.J.1    Tomasi, T.B.2
  • 24
    • 0027420419 scopus 로고
    • Large-scale production of Vibrio cholera toxin B subunit for use in oral vaccines
    • 24 Lebens M, Johansson S, Osek J, Lindblad M, Holmgren J. Large-scale production of Vibrio cholera toxin B subunit for use in oral vaccines. Biotechn 1993; 11:1574-8.
    • (1993) Biotechn , vol.11 , pp. 1574-1578
    • Lebens, M.1    Johansson, S.2    Osek, J.3    Lindblad, M.4    Holmgren, J.5
  • 25
    • 0040172243 scopus 로고
    • Recombinant system for overproduction of cholera toxin B subunit in Vibrio cholera as a basis for vaccine development
    • 25 Sanchez J, Holmgren J. Recombinant system for overproduction of cholera toxin B subunit in Vibrio cholera as a basis for vaccine development. Proc Natl Acad Sci USA 1989; 86:481-5.
    • (1989) Proc Natl Acad Sci USA , vol.86 , pp. 481-485
    • Sanchez, J.1    Holmgren, J.2
  • 26
    • 0018221811 scopus 로고
    • Identification of Escherichia coli heat-labile enterotoxin by means of a ganglioside immunosorbant assay (GM1-ELISA) procedure
    • 26 Svennerholm AM, Holmgren J. Identification of Escherichia coli heat-labile enterotoxin by means of a ganglioside immunosorbant assay (GM1-ELISA) procedure. Curr Microbiol 1978; 1:19-23.
    • (1978) Curr Microbiol , vol.1 , pp. 19-23
    • Svennerholm, A.M.1    Holmgren, J.2
  • 27
    • 0002953226 scopus 로고
    • Passive cutaneous anaphylaxis
    • Ackroyd JF. eds. Oxford: Blackwell Scientific Publications
    • 27 Ovary Z. Passive cutaneous anaphylaxis. In: Ackroyd JF. eds. Immunological Methods. Oxford: Blackwell Scientific Publications, 1964; 259-84.
    • (1964) Immunological Methods , pp. 259-284
    • Ovary, Z.1
  • 28
    • 0017357525 scopus 로고
    • Antigen and antibody detection by in vivo methods; A re-evaluation of passive cutaneous anaphylactic reactions
    • 28 Watanabe N, Ovary Z. Antigen and antibody detection by in vivo methods; A re-evaluation of passive cutaneous anaphylactic reactions. J Immunol Meth 1977; 14:381-90.
    • (1977) J Immunol Meth , vol.14 , pp. 381-390
    • Watanabe, N.1    Ovary, Z.2
  • 29
    • 0020061501 scopus 로고
    • Immunological responses to fed protein antigens in mice. I. Reversal of tolerance to ovalbumin by cyclophosphamide
    • 29 Mowat AM, Strobel S, Drummond HE, Ferguson A. Immunological responses to fed protein antigens in mice. I. Reversal of tolerance to ovalbumin by cyclophosphamide. Immunology 1982; 45:105-13.
    • (1982) Immunology , vol.45 , pp. 105-113
    • Mowat, A.M.1    Strobel, S.2    Drummond, H.E.3    Ferguson, A.4
  • 30
    • 0027512515 scopus 로고
    • Allergen-specific modulation of cytokine synthesis patterns and IgE responses in vivo with chemically modified allergens
    • 30 Gieni RS, Yang X, Hayglass KT. Allergen-specific modulation of cytokine synthesis patterns and IgE responses in vivo with chemically modified allergens. J Immunol 1993; 150:302-10.
    • (1993) J Immunol , vol.150 , pp. 302-310
    • Gieni, R.S.1    Yang, X.2    Hayglass, K.T.3
  • 31
    • 0031081395 scopus 로고    scopus 로고
    • Suppression of a delayed-type hypersensitivity and IgE antibody responses to ovalbumin by intranasal administration of Escerichia coli heat-labile enterotoxin B subunit-conjugated ovalbumin
    • 31 Tamura SI, Hatori E, Tsuruhara T, Aizawa C, Kurata T. Suppression of a delayed-type hypersensitivity and IgE antibody responses to ovalbumin by intranasal administration of Escerichia coli heat-labile enterotoxin B subunit-conjugated ovalbumin. Vaccine 1997; 15:225-9.
    • (1997) Vaccine , vol.15 , pp. 225-229
    • Tamura, S.I.1    Hatori, E.2    Tsuruhara, T.3    Aizawa, C.4    Kurata, T.5
  • 32
    • 0032007191 scopus 로고    scopus 로고
    • Immunological consequences of intervention in established immune responses by feeding protein antigens
    • 32 Leishman AJ, Garside P, Mowat AM. Immunological consequences of intervention in established immune responses by feeding protein antigens. Cell Immunol 1998; 183 (2):137-48.
    • (1998) Cell Immunol , vol.183 , Issue.2 , pp. 137-148
    • Leishman, A.J.1    Garside, P.2    Mowat, A.M.3
  • 33
    • 0030853601 scopus 로고    scopus 로고
    • Glucocorticoids inhibit human antigen-specific and enhance total IgE and IgG4 production due to differential effects on T and B cells in vitro
    • 33 Akdis GA, Blesken T, Akdis M, Alkan SS, Heusser CH, Blaser K. Glucocorticoids inhibit human antigen-specific and enhance total IgE and IgG4 production due to differential effects on T and B cells in vitro. Eur J Immunol 1997; 27:2351-7.
    • (1997) Eur J Immunol , vol.27 , pp. 2351-2357
    • Akdis, G.A.1    Blesken, T.2    Akdis, M.3    Alkan, S.S.4    Heusser, C.H.5    Blaser, K.6
  • 35
    • 0029097974 scopus 로고
    • Hydrocortisone enhances total IgE levels - But not the synthesis of allergen-specific IgE - In a monocyte-dependent manner
    • 35 Bohle B, Willheim M, Baier K, Stadler B, Sitzauer S, Scheiner O, Kraft D, Ebner C. Hydrocortisone enhances total IgE levels - but not the synthesis of allergen-specific IgE - in a monocyte-dependent manner. Clin Exp Immunol 1995; 101:474-9.
    • (1995) Clin Exp Immunol , vol.101 , pp. 474-479
    • Bohle, B.1    Willheim, M.2    Baier, K.3    Stadler, B.4    Sitzauer, S.5    Scheiner, O.6    Kraft, D.7    Ebner, C.8
  • 36
    • 0026051430 scopus 로고
    • Relation between airway responsiveness and serum IgE in children with asthma and in apparently normal children
    • 36 Sears MR, Burrows B, Flannery EM, Herbison GP, Hewitt CJ, Holdaway MD. Relation between airway responsiveness and serum IgE in children with asthma and in apparently normal children. N Engl J Med 1991; 101:1067-71.
    • (1991) N Engl J Med , vol.101 , pp. 1067-1071
    • Sears, M.R.1    Burrows, B.2    Flannery, E.M.3    Herbison, G.P.4    Hewitt, C.J.5    Holdaway, M.D.6
  • 37
    • 0002123367 scopus 로고
    • The immunizing cure of hay fever
    • 37 Curtis H. The immunizing cure of hay fever. Med News 1900; 74:16-8.
    • (1900) Med News , vol.74 , pp. 16-18
    • Curtis, H.1
  • 38
    • 50249230114 scopus 로고
    • Prophylactic inoculation against hay fever
    • 38 Noon L. Prophylactic inoculation against hay fever. Lancet 1911; 1:1572-3.
    • (1911) Lancet , vol.1 , pp. 1572-1573
    • Noon, L.1
  • 42
    • 0028302017 scopus 로고
    • A 3-year double-blind placebo-controlled study with specific oral immunotherapy to Dermatophagoides: Evidence of safety and efficacy in paediatric patients
    • 42 Giovane AL, Bardare M, Passalacqua G, Ruffoni S, Scordamaglia A, Ghezzi E, Canonica GW. A 3-year double-blind placebo-controlled study with specific oral immunotherapy to Dermatophagoides: evidence of safety and efficacy in paediatric patients. Clin Exp Allergy 1994; 24:53-9.
    • (1994) Clin Exp Allergy , vol.24 , pp. 53-59
    • Giovane, A.L.1    Bardare, M.2    Passalacqua, G.3    Ruffoni, S.4    Scordamaglia, A.5    Ghezzi, E.6    Canonica, G.W.7
  • 43
    • 0028232715 scopus 로고
    • A double-blind, placebo-controlled trial by the sublingual route of immunotherapy with a standardized grass pollen extract
    • 43 Sabbah A, Hassoun S, Le Sellin J, André C, Sicard H. A double-blind, placebo-controlled trial by the sublingual route of immunotherapy with a standardized grass pollen extract. Allergy 1994; 49:309-13.
    • (1994) Allergy , vol.49 , pp. 309-313
    • Sabbah, A.1    Hassoun, S.2    Le Sellin, J.3    André, C.4    Sicard, H.5
  • 46
    • 0031933625 scopus 로고    scopus 로고
    • Selective tolerization of Th-like cells after nasal administration of a cholera toxoid-LACK conjugate
    • 46 McSorley SJ, Rask C, Pichot R, Julia V, Czerkinsky C, Gleichenhaus N. Selective tolerization of Th-like cells after nasal administration of a cholera toxoid-LACK conjugate. Eur J Immunol 1998; 28:424-32.
    • (1998) Eur J Immunol , vol.28 , pp. 424-432
    • McSorley, S.J.1    Rask, C.2    Pichot, R.3    Julia, V.4    Czerkinsky, C.5    Gleichenhaus, N.6
  • 47
    • 0033495868 scopus 로고    scopus 로고
    • Treatment of experimental autoimmune arthritis by nasal administration of a type II collagen-cholera toxoid conjugate vaccine
    • 47 Tarkowski A, Sun J-B, Holmdahl R, Holmgren J, Czerkinsky C. Treatment of experimental autoimmune arthritis by nasal administration of a type II collagen-cholera toxoid conjugate vaccine. Arthritis Rheum 1999; 42:1628-34.
    • (1999) Arthritis Rheum , vol.42 , pp. 1628-1634
    • Tarkowski, A.1    Sun, J.-B.2    Holmdahl, R.3    Holmgren, J.4    Czerkinsky, C.5
  • 48
    • 0027538442 scopus 로고
    • Direct evidence for anergy in T lymphocytes tolerized by oral administration of ovalbumin
    • 48 Melamed D, Friedman A. Direct evidence for anergy in T lymphocytes tolerized by oral administration of ovalbumin. Eur J Immunol 1993; 23:935-42.
    • (1993) Eur J Immunol , vol.23 , pp. 935-942
    • Melamed, D.1    Friedman, A.2
  • 49
    • 0028040873 scopus 로고
    • In vivo tolerization of Th1 lymphocytes following a single feeding with ovalbumin: Anergy in the absence of suppression
    • 49 Melamed D, Friedman A. In vivo tolerization of Th1 lymphocytes following a single feeding with ovalbumin: anergy in the absence of suppression. Eur J Immunol 1994; 24:1974-81.
    • (1994) Eur J Immunol , vol.24 , pp. 1974-1981
    • Melamed, D.1    Friedman, A.2
  • 50
    • 0028845021 scopus 로고
    • Immunosuppressive and anti-inflammatory properties of interleukin 10
    • 50 de Vries JE. Immunosuppressive and anti-inflammatory properties of interleukin 10. Ann Med 1995; 27:537-41.
    • (1995) Ann Med , vol.27 , pp. 537-541
    • De Vries, J.E.1
  • 51
    • 0033209824 scopus 로고    scopus 로고
    • Suppressive versus stimulatory effects of allergen/cholera toxoid (CTB) conjugates depending on the nature of the allergen in a murine model of type I allergy
    • 51 Wiedermann U, Jahn-Schmid B, Lindblad M, Rask C, Holmgren J, Kraft D, Ebner C. Suppressive versus stimulatory effects of allergen/cholera toxoid (CTB) conjugates depending on the nature of the allergen in a murine model of type I allergy. Int Immunol 1999; 11:1717-24.
    • (1999) Int Immunol , vol.11 , pp. 1717-1724
    • Wiedermann, U.1    Jahn-Schmid, B.2    Lindblad, M.3    Rask, C.4    Holmgren, J.5    Kraft, D.6    Ebner, C.7
  • 52
    • 0027993367 scopus 로고
    • Regulation of IgE responses to inhaled antigen in mice by antigen-specific γδ T cells
    • 52 McMenamin C, Pimm C, McKersey M, Holt PG. Regulation of IgE responses to inhaled antigen in mice by antigen-specific γδ T cells. Science 1994; 265:1869-71.
    • (1994) Science , vol.265 , pp. 1869-1871
    • McMenamin, C.1    Pimm, C.2    McKersey, M.3    Holt, P.G.4
  • 53
    • 0026046280 scopus 로고
    • Antigen-driven bystander suppression after oral administration of antigens
    • 53 Miller A, Lider O, Weiner HL. Antigen-driven bystander suppression after oral administration of antigens. J Exp Med 1991; 174:791-8.
    • (1991) J Exp Med , vol.174 , pp. 791-798
    • Miller, A.1    Lider, O.2    Weiner, H.L.3
  • 54
    • 0024474813 scopus 로고
    • Defence against allergic sensitization in the healthy lung: The role of inhalation tolerance
    • 54 Holt PG, McMenamin C. Defence against allergic sensitization in the healthy lung: the role of inhalation tolerance. Clin Exp Allergy 1989; 19:255-62.
    • (1989) Clin Exp Allergy , vol.19 , pp. 255-262
    • Holt, P.G.1    McMenamin, C.2
  • 55
    • 0032030636 scopus 로고    scopus 로고
    • A mucosal intranet: Intestinal epithelial cells down-regulate intraepithelial, but not peripheral, T cell lymphocytes
    • 55 Yamamoto M, Fujihashi K, Kawabata K, McGhee J, Kiyono H. A mucosal intranet: Intestinal epithelial cells down-regulate intraepithelial, but not peripheral, T cell lymphocytes. J Immunol 1998; 160:2188-96.
    • (1998) J Immunol , vol.160 , pp. 2188-2196
    • Yamamoto, M.1    Fujihashi, K.2    Kawabata, K.3    McGhee, J.4    Kiyono, H.5
  • 56


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.