Nasal administration of glutamate decarboxylase (GAD65) peptides induces Th2 responses and prevents murine insulin-dependent diabetes

Journal of Experimental Medicine

Volumn 183, Issue 4, 1996, Pages 1561-1567

  Tian, Jide ^a   Atkinson, Mark A ^b   Clare Salzler, Michael ^b   Herschenfeld, Alan ^a   Forsthuber, Thomas ^c   Lehmann, Paul V ^c   Kaufman, Daniel L ^a,d  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF FLORIDA   (United States)

^c CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AUTOANTIBODY; CD4 ANTIGEN; CD8 ANTIGEN; CYTOKINE; GAMMA INTERFERON; GLUTAMATE DECARBOXYLASE; IMMUNOGLOBULIN G ANTIBODY; IMMUNOGLOBULIN M ANTIBODY; INTERLEUKIN 5; RECOMBINANT GAMMA INTERFERON; RECOMBINANT INTERLEUKIN 5; SYNTHETIC PEPTIDE; THY 1 ANTIGEN;

ADOPTIVE TRANSFER; ANIMAL CELL; ANIMAL MODEL; ARTICLE; AUTOIMMUNITY; COMBINED IMMUNODEFICIENCY; CONTROLLED STUDY; FEMALE; GLUCOSE BLOOD LEVEL; IMMUNOLOGICAL TOLERANCE; IMMUNOTHERAPY; INSULIN DEPENDENT DIABETES MELLITUS; INTRANASAL DRUG ADMINISTRATION; LYMPHOCYTE PROLIFERATION; MOUSE; NONHUMAN; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; T LYMPHOCYTE SUBPOPULATION;

ADMINISTRATION, INTRANASAL; ANIMALS; AUTOANTIBODIES; DIABETES MELLITUS, TYPE 1; FEMALE; GLUTAMATE DECARBOXYLASE; IMMUNE TOLERANCE; IMMUNOGLOBULIN G; IMMUNOGLOBULIN ISOTYPES; IMMUNOTHERAPY, ADOPTIVE; INCIDENCE; INTERFERON TYPE II; INTERLEUKIN-5; ISLETS OF LANGERHANS; MICE; MICE, INBRED NOD; MICE, SCID; PEPTIDE FRAGMENTS; TH1 CELLS; TH2 CELLS;

EID: 0029923430     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.183.4.1561     Document Type: Article

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