Siglec-F is a novel intestinal M cell marker

Biochemical and Biophysical Research Communications

Volumn 479, Issue 1, 2016, Pages 1-4

  Gicheva, Nadezhda ^a   Macauley, Matthew S ^b   Arlian, Britni M ^b   Paulson, James C ^b   Kawasaki, Norihito ^a,b  

^a INSTITUTE OF FOOD RESEARCH   (United Kingdom)

^b SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

M cell; Oral vaccine; Peyer's patch; Siglec

Indexed keywords

MONOCLONAL ANTIBODY; PROTEIN ANTIBODY; SIALIC ACID BINDING IMMUNOGLOBULIN LIKE LECTIN; SIALIC ACID BINDING IMMUNOGLOBULIN LIKE LECTIN F; UNCLASSIFIED DRUG; BIOLOGICAL MARKER; DIFFERENTIATION ANTIGEN; PROTEIN BINDING; SIGLEC5 PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; IMMUNOHISTOCHEMISTRY; INTESTINAL MICROFOLD CELL; INTESTINE CELL; INTESTINE MUCOSA; MOUSE; NONHUMAN; PEYER PATCH; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; RAT; ANIMAL; ANTIBODY AFFINITY; BAGG ALBINO MOUSE; C57BL MOUSE; CELL MEMBRANE; CHO CELL LINE; CRICETULUS; CYTOLOGY; FLOW CYTOMETRY; GENETICS; HAMSTER; HEK293 CELL LINE; HUMAN; IMMUNOLOGY; KNOCKOUT MOUSE; LEWIS RAT; METABOLISM;

ANIMALS; ANTIBODIES, MONOCLONAL; ANTIBODY AFFINITY; ANTIGENS, DIFFERENTIATION, MYELOMONOCYTIC; BIOMARKERS; CELL MEMBRANE; CHO CELLS; CRICETINAE; CRICETULUS; FLOW CYTOMETRY; HEK293 CELLS; HUMANS; IMMUNOHISTOCHEMISTRY; INTESTINAL MUCOSA; MICE, INBRED BALB C; MICE, INBRED C57BL; MICE, KNOCKOUT; PEYER'S PATCHES; PROTEIN BINDING; RATS, INBRED LEW;

EID: 84988432368     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2016.08.055     Document Type: Article

References (19)

1. [1] Mabbott, N.A., Donaldson, D.S., Ohno, H., Williams, I.R., Mahajan, A., Microfold (M) cells: important immunosurveillance posts in the intestinal epithelium. Mucosal Immunol. 6 (2013), 666–677.
2. [2] Schulz, O., Pabst, O., Antigen sampling in the small intestine. Trends Immunol. 34 (2013), 155–161.
3. [3] Kim, S.-H., Jang, Y.-S., Antigen targeting to M cells for enhancing the efficacy of mucosal vaccines. Exp. Mol. Med., 46, 2014, e85.
4. [4] Nochi, T., Yuki, Y., Matsumura, A., Mejima, M., Terahara, K., Kim, D.Y., Fukuyama, S., Iwatsuki-Horimoto, K., Kawaoka, Y., Kohda, T., Kozaki, S., Igarashi, O., Kiyono, H., A novel M cell-specific carbohydrate-targeted mucosal vaccine effectively induces antigen-specific immune responses. J. Exp. Med. 204 (2007), 2789–2796.
5. [5] Shima, H., Watanabe, T., Fukuda, S., Fukuoka, S.-I., Ohara, O., Ohno, H., A novel mucosal vaccine targeting Peyer's patch M cells induces protective antigen-specific IgA responses. Int. Immunol. 26 (2014), 619–625.
6. [6] Hase, K., Kawano, K., Nochi, T., Pontes, G.S., Fukuda, S., Ebisawa, M., Kadokura, K., Tobe, T., Fujimura, Y., Kawano, S., Yabashi, A., Waguri, S., Nakato, G., Kimura, S., Murakami, T., Iimura, M., Hamura, K., Fukuoka, S., Lowe, A.W., Itoh, K., Kiyono, H., Ohno, H., Uptake through glycoprotein 2 of FimH(+) bacteria by M cells initiates mucosal immune response. Nature 462 (2009), 226–230.
7. [7] Macauley, M.S., Crocker, P.R., Paulson, J.C., Siglec-mediated regulation of immune cell function in disease. Nat. Rev. Immunol. 14 (2014), 653–666.
8. [8] Brinkman-Van der Linden, E.C., Hurtado-Ziola, N., Hayakawa, T., Wiggleton, L., Benirschke, K., Varki, A., Varki, N., Human-specific expression of Siglec-6 in the placenta. Glycobiology 17 (2007), 922–931.
9. [9] Mitra, N., Banda, K., Altheide, T.K., Schaffer, L., Johnson-Pais, T.L., Beuten, J., Leach, R.J., Angata, T., Varki, N., Varki, A., SIGLEC12, a human-specific segregating (pseudo)gene, encodes a signaling molecule expressed in prostate carcinomas. J. Biol. Chem. 286 (2011), 23003–23011.
10. [10] Ali, S.R., Fong, J.J., Carlin, A.F., Busch, T.D., Linden, R., Angata, T., Areschoug, T., Parast, M., Varki, N., Murray, J., Nizet, V., Varki, A., Siglec-5 and Siglec-14 are polymorphic paired receptors that modulate neutrophil and amnion signaling responses to group B Streptococcus. J. Exp. Med. 211 (2014), 1231–1242.
11. [11] Rochereau, N., Drocourt, D., Perouzel, E., Pavot, V., Redelinghuys, P., Brown, G.D., Tiraby, G., Roblin, X., Verrier, B., Genin, C., Corthésy, B., Paul, S., Dectin-1 is essential for reverse transcytosis of glycosylated SIgA-antigen complexes by intestinal M cells. PLoS Biol., 11, 2013, e1001658.
12. [12] Angata, T., Nycholat, C.M., Macauley, M.S., Therapeutic targeting of Siglecs using antibody- and glycan-based approaches. Trends Pharmacol. Sci. 36 (2015), 645–660.
13. [13] Tateno, H., Crocker, P.R., Paulson, J.C., Mouse Siglec-F and human Siglec-8 are functionally convergent paralogs that are selectively expressed on eosinophils and recognize 6'-sulfo-sialyl Lewis X as a preferred glycan ligand. Glycobiology 15 (2005), 1125–1135.
14. [14] Kiwamoto, T., Katoh, T., Evans, C.M., Janssen, W.J., Brummet, M.E., Hudson, S.A., Zhu, Z., Tiemeyer, M., Bochner, B.S., Endogenous airway mucins carry glycans that bind Siglec-F and induce eosinophil apoptosis. J. Allergy Clin. Immunol. 135 (2015), 1329–1340.
15. [15] Zhang, M., Angata, T., Cho, J.Y., Miller, M., Broide, D.H., Varki, A., Defining the in vivo function of Siglec-F, a CD33-related Siglec expressed on mouse eosinophils. Blood 109 (2007), 4280–4287.
16. [16] Kirby, A.C., Coles, M.C., Kaye, P.M., Alveolar macrophages transport pathogens to lung draining lymph nodes. J. Immunol. 183 (2009), 1983–1989.
17. [17] Terahara, K., Yoshida, M., Igarashi, O., Nochi, T., Pontes, G.S., Hase, K., Ohno, H., Kurokawa, S., Mejima, M., Takayama, N., Yuki, Y., Lowe, A.W., Kiyono, H., Comprehensive gene expression profiling of Peyer's patch M cells, villous M-like cells, and intestinal epithelial cells. J. Immunol. 180 (2008), 7840–7846.
18. [18] Pfrengle, F., Macauley, M.S., Kawasaki, N., Paulson, J.C., Copresentation of antigen and ligands of siglec-G induces B cell tolerance independent of CD22. J. Immunol. 191 (2013), 1724–1731.
19. [19] Tateno, H., Li, H., Schur, M.J., Bovin, N., Crocker, P.R., Wakarchuk, W.W., Paulson, J.C., Distinct endocytic mechanisms of CD22 (Siglec-2) and Siglec-F reflect roles in cell signaling and innate immunity. Mol. Cell. Biol. 27 (2007), 5699–5710.