Quantitative trait loci controlling allergen-induced airway hyperresponsiveness in inbred mice

American Journal of Respiratory Cell and Molecular Biology

Volumn 23, Issue 4, 2000, Pages 537-545

  Ewart, S L ^a   Kuperman, D ^a   Schadt, E ^a   Tankersley, C ^a   Grupe, A ^a   Shubitowski, D M ^a   Peltz, G ^a   Wills Karp, M ^a  

^a CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 0033791849     PISSN: 10441549     EISSN: None     Source Type: Journal    
DOI: 10.1165/ajrcmb.23.4.4199     Document Type: Article

References (41)

1. Changing patterns of asthma hospitalization among children: 1979 to 1987
2. Genetic analysis of allergic disease in twins
3. Genetic factors in nonspecific bronchial hyperreactivity: An epidemiologic study
4. A genome-wide search for linkage to asthma. German Asthma Genetics Group
5. A genome-wide search for asthma susceptibility loci in ethnically diverse populations
6. Genome-wide search for asthma susceptibility loci in a founder population: The Collaborative Study on the Genetics of Asthma
7. A genome-wide search for quantitative trait loci underlying asthma
8. Airway hyperresponsiveness to acetylcholine: Segregation analysis and evidence for linkage to murine chromosome 6
9. Quantitative locus analysis of airway hyperresponsiveness in A/J and C57BL/6J mice
10. Quantitative trait locus mapping of airway responsiveness to chromosomes 6 and 7 in inbred mice
11. A genome-wide screen for asthma-associated quantitative trait loci in a mouse model of allergic asthma
12. Expression of airway hyperreactivity to acetylcholine as a simple autosomal recessive trait in mice
13. Resistance to antigen-induced airway hyperresponsiveness requires endogenous production of IL-12
14. Interleukin-13: Central mediator of allergic asthma
15. Genetic dissection of complex traits: Guidelines for interpreting and reporting linkage results
16. Permutation tests for multiple loci affecting a quantitative character
17. Empirical threshold values for quantitative trait mapping
18. Zmap: A QTL cartographer
19. Cyclosporin A attenuates genetic airway hyperresponsiveness in mice but not through inhibition of CD4+ or CD8+ T cells
20. Allergic eosinophil-rich inflammation develops in lungs and airways of B cell-deficient mice
21. Allergen-induced bronchial hyperreactivity and eosinophilic inflammation occur in the absence of IgE in a mouse model of asthma
22. Etiology of intrinsic asthma
23. Genetic regulation of Dermatophagoides pteronyssinus-specific IgE responsiveness: A genome-wide multipoint linkage analysis in families recruited through 2 asthmatic sibs. Collaborative Study on the Genetics of Asthma (CSGA)
24. Linkage between immunoglobulin E responses underlying asthma and rhinitis and chromosome 11q
25. Linkage analysis of IL4 and other chromosome 5q31.1 markers and total serum immunoglobulin E concentrations
26. Evidence for a locus regulating total serum IgE levels mapping to chromosome 5
27. Genetic susceptibility to asthma: Bronchial hyperresponsiveness coinherited with a major gene for atopy
28. Interleukin 4, but not interleukin 5 or eosinophils, is required in a murine model of acute airway hyperreactivity
29. Depletion of murine CD4+ T lymphocytes prevents antigen-induced airway hyperreactivity and pulmonary eosinophilia
30. QTL analysis: Further uses of 'marker regression'
31. On the mapping of QTL by regression of phenotypes on marker type
32. Mapping of body weight loci in mouse chromosome X
33. Transcription factor GATA-3 is differentially expressed in murine Th1 and Th2 cells and controls Th2-specific expression of the interleukin-5 gene
34. The transcription factor GATA-3 is necessary and sufficient for Th2 cytokine gene expression in CD4 T cells
35. Inhibition of allergic inflammation in a routine model of asthma by expression of a dominant-negative mutant of GATA-3