The role of innate immunity activation in house dust mite allergy

Trends in Molecular Medicine

Volumn 17, Issue 10, 2011, Pages 604-611

  Jacquet, Alain ^a  

^a CHULALONGKORN UNIVERSITY   (Thailand)

Author keywords

[No Author keywords available]

Indexed keywords

BETA GLUCAN; C TYPE LECTIN RECEPTOR; CELL SURFACE RECEPTOR; DECTIN 2; HOUSE DUST ALLERGEN; IMMUNOGLOBULIN E; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INFLAMMASOME; INTERFERON; INTERLEUKIN 1BETA; INTERLEUKIN 4; INTERLEUKIN 5; INTERLEUKIN 6; INTERLEUKIN 8; LECTIN RECEPTOR; LIPOPOLYSACCHARIDE; LUNG SURFACTANT; MITOGEN ACTIVATED PROTEIN KINASE; NUCLEOTIDE BINDING OLIGOMERIZATION DOMAIN LIKE RECEPTOR; PATHOGEN RECOGNITION RECEPTOR; PATTERN RECOGNITION RECEPTOR; PROTEIN ZO1; PROTEINASE ACTIVATED RECEPTOR; RECEPTOR; RECOMBINANT INTERLEUKIN 10; RETINOIC ACID; RETINOIC ACID INDUCIBLE PROTEIN I; TOLL LIKE RECEPTOR; TOLL LIKE RECEPTOR 4; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG;

ALLERGIC ASTHMA; ANTIGEN PRESENTING CELL; ATOPIC DERMATITIS; BASOPHIL; CELL ACTIVATION; CELL MIGRATION; CYTOKINE PRODUCTION; CYTOKINE RELEASE; DENDRITIC CELL; DERMATOPHAGOIDES; DOWN REGULATION; ENDOTHELIUM CELL; ENZYME ACTIVATION; EOSINOPHIL; EPITHELIUM CELL; FIBROBLAST; GENE OVEREXPRESSION; GLYCOSYLATION; GRANULOCYTE; HOUSE DUST ALLERGY; HUMAN; IMMUNOGLOBULIN PRODUCTION; INFLAMMATORY CELL; INNATE IMMUNITY; MACROPHAGE; NONHUMAN; PATTERN RECOGNITION; PERENNIAL RHINITIS; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; RECEPTOR UPREGULATION; REVIEW; SIGNAL TRANSDUCTION; TH2 CELL;

ANIMALS; ANTIGENS, DERMATOPHAGOIDES; HUMANS; HYPERSENSITIVITY; IMMUNITY, INNATE; INFLAMMATION; LECTINS, C-TYPE; PYROGLYPHIDAE; RECEPTORS, PROTEINASE-ACTIVATED; TOLL-LIKE RECEPTORS;

ACARI; PYROGLYPHIDAE;

EID: 80053562644     PISSN: 14714914     EISSN: 1471499X     Source Type: Journal    
DOI: 10.1016/j.molmed.2011.05.014     Document Type: Review

References (70)

1. Arshad S.H. Does exposure to indoor allergens contribute to the development of asthma and allergy?. Curr. Allergy Asthma Rep. 2010, 10:49-55.
2. Willart M.A., Lambrecht B.N. The danger within: endogenous danger signals, atopy and asthma. Clin. Exp. Allergy 2009, 39:12-19.
3. Thomas W.R., et al. House dust mite allergens in asthma and allergy. Trends Mol. Med. 2010, 16:321-328.
4. Douwes J., et al. (1→3)-β-d-glucan and endotoxin in house dust and peak flow variability in children. Am. J. Respir. Crit. Care Med. 2000, 162:1348-1354.
5. Valerio C.R., et al. Bacterial 16S ribosomal DNA in house dust mite cultures. J. Allergy Clin. Immunol. 2005, 116:1296-1300.
6. Takeuchi O., Akira S. Pattern recognition receptors and inflammation. Cell 2010, 140:805-820.
7. Grainger J.R., et al. Microbe-dendritic cell dialog controls regulatory T-cell fate. Immunol. Rev. 2010, 234:305-316.
8. Chen G.Y., Nuñez G. Sterile inflammation: sensing and reacting to damage. Nat. Rev. Immunol. 2010, 10:826-837.
9. Eisenbarth S.C., et al. Lipopolysaccharide-enhanced, toll-like receptor 4-dependent T helper cell type 2 responses to inhaled antigen. J. Exp. Med. 2002, 196:1645-1651.
10. Phipps S., et al. Toll/IL-1 signaling is critical for house dust mite-specific Th1 and Th2 responses. Am. J. Respir. Crit. Care Med. 2009, 179:883-893.
11. Marichal T., et al. Interferon response factor 3 is essential for house dust mite-induced airway allergy. J. Allergy Clin. Immunol. 2010, 126:836-844.
12. Hammad H., et al. House dust mite allergen induces asthma via Toll-like receptor 4 triggering of airway structural cells. Nat. Med. 2009, 15:410-416.
13. Trompette A., et al. Allergenicity resulting from functional mimicry of a Toll-like receptor complex protein. Nature 2009, 457:585-588.
14. Ichikawa S., et al. Lipopolysaccharide binding of the mite allergen Der f 2. Genes Cells 2009, 14:1055-1065.
15. Chiou Y.L., Lin C.Y. Der p2 activates airway smooth muscle cells in a TLR2/MyD88-dependent manner to induce an inflammatory response. J. Cell Physiol. 2009, 220:311-318.
16. Mueller G.A., et al. Der p 5 crystal structure provides insight into the group 5 dust mite allergens. J. Biol. Chem. 2010, 285:25394-25401.
17. Kauffman H.F., et al. House dust mite major allergens Der p 1 and Der p 5 activate human airway-derived epithelial cells by protease-dependent and protease-independent mechanisms. Clin. Mol. Allergy 2006, 4:5.
18. Mueller G.A., et al. The structure of the dust mite allergen Der p 7 reveals similarities to innate immune proteins. J. Allergy Clin. Immunol. 2010, 125:909-917.
19. Nathan A.T., et al. Innate immune responses of airway epithelium to house dust mite are mediated through beta-glucan-dependent pathways. J. Allergy Clin. Immunol. 2009, 123:612-618.
20. Barrett N.A., et al. Dectin-2 recognition of house dust mite triggers cysteinyl leukotriene generation by DCs. J. Immunol. 2009, 182:1119-1128.
21. Barrett N.A., et al. Dectin-2 mediates Th2 immunity through the generation of cysteinyl leukotrienes. J. Exp. Med. 2011, 208:593-604.
22. Royer P.J., et al. The mannose receptor mediates the uptake of diverse native allergens by dendritic cells and determines allergen-induced T cell polarization through modulation of IDO activity. J. Immunol. 2010, 185:1522-1531.
23. Hsu S.C., et al. Functional interaction of common allergens and a C-type lectin receptor, DC-specific ICAM3-grabbing non-integrin (DC-sign), on human DCs. J. Biol. Chem. 2010, 285:7903-7910.
24. Lee C.G., et al. Role of chitin and chitinase/chitinase-like proteins in inflammation, tissue remodeling, and injury. Annu. Rev. Physiol. 2011, 73:479-501.
25. de Koning H.D., et al. A comprehensive analysis of pattern recognition receptors in normal and inflamed human epidermis: up-regulation of dectin-1 in psoriasis. J. Invest. Dermatol. 2010, 130:2611-2620.
26. Dai X., et al. Mite allergen is a danger signal for the skin via activation of inflammasome in keratinocytes. J. Allergy Clin. Immunol. 2011, 127:806-814.
27. Dale C., Vergnolle N. Protease signaling to G protein-coupled receptors: implications for inflammation and pain. J. Recept. Signal Transduct. Res. 2008, 28:29-37.
28. Rallabhandi P., et al. Analysis of proteinase-activated receptor 2 and TLR4 signal transduction: a novel paradigm for receptor cooperativity. J. Biol. Chem. 2008, 283:24314-24325.
29. Cho H.J., et al. House dust mite extract activates apical Cl(-) channels through protease-activated receptor 2 in human airway epithelia. J. Cell Biochem. 2010, 109:1254-1263.
30. Asokananthan N., et al. House dust mite allergens induce proinflammatory cytokines from respiratory epithelial cells: the cysteine protease allergen, Der p 1, activates protease-activated receptor (PAR)-2 and inactivates PAR-1. J. Immunol. 2002, 169:4572-4578.
31. Adam E., et al. The house dust mite allergen Der p 1, unlike Der p 3, stimulates the expression of interleukin-8 in human airway epithelial cells via a proteinase-activated receptor-2-independent mechanism. J. Biol. Chem. 2006, 281:6910-6923.
32. Shi J., et al. Induction of IL-6 and IL-8 by house dust mite allergen Der p1 in cultured human nasal epithelial cells is associated with PAR/PI3K/NFkappaB signaling. ORL J. Otorhinolaryngol. Relat. Spec. 2010, 72:256-265.
33. King C., et al. Dust mite proteolytic allergens induce cytokine release from cultured airway epithelium. J. Immunol. 1998, 161:3645-3651.
34. Sun G., et al. Interaction of mite allergens Der p3 and Der p9 with protease-activated receptor-2 expressed by lung epithelial cells. J. Immunol. 2001, 167:1014-1021.
35. Kato T., et al. Mite serine protease activates protease-activated receptor-2 and induces cytokine release in human keratinocytes. Allergy 2009, 64:1366-1374.
36. Roelandt T., et al. Proteolytically active allergens cause barrier breakdown. J. Invest. Dermatol. 2008, 128:1878-1880.
37. Heijink I.H., et al. House dust mite-promoted epithelial-to-mesenchymal transition in human bronchial epithelium. Am. J. Respir. Cell. Mol. Biol. 2010, 42:69-79.
38. Heijink I.H., et al. EGFR signaling contributes to house dust mite-induced epithelial barrier dysfunction. Eur. Respir. J. 2010, 36:1016-1026.
39. Kalsheker N.A., et al. The house dust mite allergen Der p1 catalytically inactivates alpha 1-antitrypsin by specific reactive centre loop cleavage: a mechanism that promotes airway inflammation and asthma. Biochem. Biophys. Res. Commun. 1996, 221:59-61.
40. Deb R., et al. Major house dust mite allergens Dermatophagoides pteronyssinus 1 and Dermatophagoides farinae 1 degrade and inactivate lung surfactant proteins A and D. J. Biol. Chem. 2007, 282:36808-36819.
41. Wan H., et al. Quantitative structural and biochemical analyses of tight junction dynamics following exposure of epithelial cells to house dust mite allergen Der p 1. Clin. Exp. Allergy 2000, 30:685-698.
42. Wan H., et al. The transmembrane protein occludin of epithelial tight junctions is a functional target for serine peptidases from faecal pellets of Dermatophagoides pteronyssinus. Clin. Exp. Allergy 2001, 31:279-294.
43. Ghaemmaghami A.M., et al. The proteolytic activity of the major dust mite allergen Der p 1 conditions dendritic cells to produce less interleukin-12: allergen-induced Th2 bias determined at the dendritic cell level. Clin. Exp. Allergy 2002, 32:1468-1475.
44. Furmonaviciene R., et al. The protease allergen Der p 1 cleaves cell surface DC-SIGN and DC-SIGNR: experimental analysis of in silico substrate identification and implications in allergic responses. Clin. Exp. Allergy 2007, 37:231-242.
45. Maneechotesuwan K., et al. Der p 1 suppresses indoleamine 2, 3-dioxygenase in dendritic cells from house dust mite-sensitive patients with asthma. J. Allergy Clin. Immunol. 2009, 123:239-248.
46. Nakamura Y., et al. House dust mite allergen Der f 1 can induce the activation of latent TGF-beta via its protease activity. FEBS Lett. 2009, 583:2088-2092.
47. Chen C.L., et al. House dust mite Dermatophagoides farinae augments proinflammatory mediator productions and accessory function of alveolar macrophages: implications for allergic sensitization and inflammation. J. Immunol. 2003, 170:528-536.
48. Coward W.R., et al. Allergen activates peripheral blood eosinophil nuclear factor-kappaB to generate granulocyte macrophage-colony stimulating factor, tumour necrosis factor-alpha and interleukin-8. Clin. Exp. Allergy 2004, 34:1071-1078.
49. Fujisawa T., et al. House dust mite extract induces interleukin-9 expression in human eosinophils. Allergol. Int. 2008, 57:141-146.
50. Pichavant M., et al. Asthmatic bronchial epithelium activated by the proteolytic allergen Der p 1 increases selective dendritic cell recruitment. J. Allergy Clin. Immunol. 2005, 115:771-778.
51. Hammad H., et al. Monocyte-derived dendritic cells exposed to Der p 1 allergen enhance the recruitment of Th2 cells: major involvement of the chemokines TARC/CCL17 and MDC/CCL22. Eur. Cytokine Netw. 2003, 14:219-228.
52. Miike S., Kita H. Human eosinophils are activated by cysteine proteases and release inflammatory mediators. J. Allergy Clin. Immunol. 2003, 111:704-713.
53. Phillips C., et al. Basophils express a type 2 cytokine profile on exposure to proteases from helminths and house dust mites. J. Leukoc. Biol. 2003, 73:165-171.
54. Yu H.S., et al. Protease allergens induce the expression of IL-25 via Erk and p38 MAPK pathway. J. Korean Med. Sci. 2010, 25:829-834.
55. Kouzaki H., et al. Proteases induce production of thymic stromal lymphopoietin by airway epithelial cells through protease-activated receptor-2. J. Immunol. 2009, 183:1427-1434.
56. Osterlund C., et al. The non-proteolytic house dust mite allergen Der p 2 induce NF-kappaB and MAPK dependent activation of bronchial epithelial cells. Clin. Exp. Allergy 2009, 39:1199-1208.
57. Park S.Y., et al. House dust mite allergen Der f 2-induced phospholipase D1 activation is critical for the production of interleukin-13 through activating transcription factor-2 activation in human bronchial epithelial cells. J. Biol. Chem. 2009, 284:20099-20110.
58. Krishnamoorthy N., et al. Activation of c-Kit in DCs regulates T helper cell differentiation and allergic asthma. Nat. Med. 2008, 14:565-573.
59. O'Neil S.E., et al. The chitinase allergens Der p 15 and Der p 18 from Dermatophagoides pteronyssinus. Clin. Exp. Allergy 2006, 36:831-839.
60. Möller G.M., et al. Increased numbers of DCs in the bronchial mucosa of atopic asthmatic patients: down-regulation by inhaled corticosteroids. Clin. Exp. Allergy 1996, 26:517-524.
61. Ying S., et al. Thymic stromal lymphopoietin expression is increased in asthmatic airways and correlates with expression of Th2-attracting chemokines and disease severity. J. Immunol. 2005, 174:8183-8190.
62. Yerkovich S.T., et al. Allergen-enhanced thrombomodulin (blood dendritic cell antigen 3, CD141) expression on DCs is associated with a TH2-skewed immune response. J. Allergy Clin. Immunol. 2009, 123:209-216.
63. Liu Y.J. Thymic stromal lymphopoietin: master switch for allergic inflammation. J. Exp. Med. 2006, 203:269-273.
64. Harada M., et al. TSLP promoter polymorphisms are associated with susceptibility to bronchial asthma. Am. J. Respir. Cell Mol. Biol. 2011, 44:787-793.
65. Knight D.A., et al. Protease-activated receptors in human airways: up-regulation of PAR-2 in respiratory epithelium from patients with asthma. J. Allergy Clin. Immunol. 2001, 108:797-803.
66. Wright J.G., Christman J.W. The role of nuclear factor kappa B in the pathogenesis of pulmonary diseases: implications for therapy. Am. J. Respir. Med. 2003, 2:211-219.
67. Umetsu D.T., et al. Regulatory T cells control the development of allergic disease and asthma. J. Allergy Clin. Immunol. 2003, 112:480-487.
68. Verhagen J., et al. Absence of T-regulatory cell expression and function in atopic dermatitis skin. J. Allergy Clin. Immunol. 2006, 117:176-183.
69. Tesse R., et al. Genetic variations in toll-like receptor pathway genes influence asthma and atopy. Allergy 2011, 66:307-316.
70. Chapman M.D., et al. Nomenclature and structural biology of allergens. J. Allergy Clin. Immunol. 2007, 119:414-420.