Chitin induces accumulation in tissue of innate immune cells associated with allergy

Nature

Volumn 447, Issue 7140, 2007, Pages 92-96

  Reese, Tiffany A ^a   Liang, Hong Erh ^a   Tager, Andrew M ^b   Luster, Andrew D ^b   Van Rooijen, Nico ^c   Voehringer, David ^a,d   Locksley, Richard M ^a  

^a HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^b MASSACHUSETTS GENERAL HOSPITAL   (United States)

^c VU UNIVERSITY AMSTERDAM   (Netherlands)

^d UNIVERSITY OF MUNICH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CHITIN; CHITINASE; INTERLEUKIN 13; INTERLEUKIN 4; LEUKOTRIENE B4; LIPOPOLYSACCHARIDE; TOLL LIKE RECEPTOR;

CHITIN; IMMUNE RESPONSE; IMMUNE SYSTEM; IMMUNITY; TRIGGER MECHANISM;

ALLERGY; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIGEN RECOGNITION; ARTICLE; BASOPHIL; CELL INFILTRATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; EOSINOPHIL; HELMINTH; INNATE IMMUNITY; MACROPHAGE ACTIVATION; MOUSE; NONHUMAN; PARASITE IMMUNITY; PRIORITY JOURNAL; PROTEIN FUNCTION; REGULATORY MECHANISM;

CRUSTACEA; FUNGI; HEXAPODA; MAMMALIA; MUS; VERMES; VERTEBRATA;

EID: 34247626970     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature05746     Document Type: Article

References (31)

1. Ramalingam, T. R., Reiman, R. M. & Wynn, T. A. Exploiting worm and allergy models to understand Th2 cytokine biology. Curr. Opin. Allergy Clin. Immunol. 5, 392-398 (2005).
2. Gordon, S. Alternative activation of macrophages. Nature Rev. Immunol. 3, 23-35 (2003).
3. Bowman, S. M. & Free, S. J. The structure and synthesis of the fungal cell wall. Bioessays 28, 799-808 (2006).
4. Zhu, Z. et al. Acidic mammalian chitinase in asthmatic Th2 inflammation and IL-13 pathway activation. Science 304, 1678-1682 (2004).
5. Nair, M. G., Guild, K. J. & Artis, D. Novel effector molecules in type 2 inflammation: lessons drawn from helminth infection and allergy. J. Immunol. 177, 1393-1399 (2006).
6. Finkelman, F. D. et al. Interleukin-4- and interleukin-13-mediated host protection against intestinal nematode parasites. Immunol. Rev. 201, 139-155 (2004).
7. Zhang, Y., Foster, J. M., Nelson, L. S., Ma, D. & Carlow, C. K. The chitin synthase genes chs-1 and chs-2 are essential for C. elegans development and responsible for chitin deposition in the eggshell and pharynx, respectively. Dev. Biol. 285, 330-339 (2005).
8. Mohrs, M., Shinkai, K., Mohrs, K. & Locksley, R. M. Analysis of type 2 immunity in vivo with a bicistronic IL-4 reporter. Immunity 15, 303-311 (2001).
9. Boot, R. G. et al. Identification of a novel acidic mammalian chitinase distinct from chitotriosidase. J. Biol. Chem. 276, 6770-6778 (2001).
10. Boot, R. G., Renkema, G. H., Strijland, A., van Zonneveld, A. J. & Aerts, J. M. Cloning of a cDNA encoding chitotriosidase, a human chitinase produced by macrophages. J. Biol. Chem. 270, 26252-26256 (1995).
11. Jin, H.M. et al. Genetic characterization of the murine Ym1 gene and identification of a cluster of highly homologous genes. Genomics 54, 316-322 (1998).
12. 4 receptor expressed on eosinophils. J. Exp. Med. 188, 1063-1074 (1998).
13. 4 and prostaglandin E2. J. Biomed. Mater. Res. 42, 517-522 (1998).
14. 4 receptor BLT1 mediates early effector T cell recruitment. Nature Immunol. 4, 982-990 (2003).
15. W-sh sash mice. Clin. Exp. Allergy 35, 82-88 (2005).
16. Machado, E. R. et al. Leukotrienes play a role in the control of parasite burden in murine strongyloidiasis. J. Immunol. 175, 3892-3899 (2005).
17. Phillips, C., Coward, W. R., Pritchard, D. I. & Hewitt, C. R. Basophils express a type 2 cytokine profile on exposure to proteases from helminths and house dust mites. J. Leukoc. Biol. 73, 165-171 (2003).
18. Shibata, Y., Foster, L. A., Bradfield, J. F. & Myrvik, Q. N. Oral administration of chitin down-regulates serum IgE levels and lung eosinophilia in the allergic mouse. J. Immunol. 164, 1314-1321 (2000).
19. Keyhani, N. O. & Roseman, S. Physiological aspects of chitin catabolism in marine bacteria. Biochim. Biophys. Acta 1473, 108-122 (1999).
20. Merzendorfer, H. & Zimoch, L. Chitin metabolism in insects: structure, function and regulation of chitin synthases and chitinases. J. Exp. Biol. 206, 4393-4412 (2003).
21. Kaku, H. et al. Plant cells recognize chitin fragments for defense signaling through a plasma membrane receptor. Proc. Natl Acad. Sci. USA 103, 11086-11091 (2006).
22. Hernandez Prada, J. A. et al. Ancient evolutionary origin of diversified variable regions demonstrated by crystal structures of an immune-type receptor in amphioxus. Nature Immunol. 7, 875-882 (2006).
23. Voehringer, D., Reese, T. A., Huang, X., Shinkai, K. & Locksley, R. M. Type 2 immunity is controlled by IL-4/IL-13 expression in hematopoietic non-eosinophil cells of the innate immune system. J. Exp. Med. 203, 1435-1446 (2006).
24. Cartier, A. et al. Prevalence of crab asthma in crab plant workers in Newfoundland and Labrador. Int. J. Circumpolar Health 63 (Suppl. 2), 333-336 (2004).
25. Adachi, O. et al. Targeted disruption of the MyD88 gene results in loss of IL-1- and IL-18-mediated function. Immunity 9, 143-150 (1998).
26. 4-induced chemotaxis and adhesion and plays a dominant role in eosinophil accumulation in a murine model of peritonitis. J. Exp. Med. 192, 439-446 (2000).
27. Voehringer, D., Shinkai, K. & Locksley, R. M. Type 2 immunity reflects orchestrated recruitment of cells committed to IL-4 production. Immunity 20, 267-277 (2004).
28. Reinhardt, R. L., Hong, S., Kang, S. J., Wang, Z. E. & Locksley, R. M. Visualization of IL-12/23p40 in vivo reveals immunostimulatory dendritic cell migrants that promote Th1 differentiation. J. Immunol. 177, 1618-1627 (2006).
29. Van Rooijen, N. & Sanders, A. Liposome mediated depletion of macrophages: mechanism of action, preparation of liposomes and applications. J. Immunol. Methods 174, 83-93 (1994).
30. Zhang, J. Q., Biedermann, B., Nitschke, L. & Crocker, P. R. The murine inhibitory receptor mSiglec-E is expressed broadly on cells of the innate immune system whereas mSiglec-F is restricted to eosinophils. Eur. J. Immunol. 34, 1175-1184 (2004).
31. Glasser, S. W. et al. Genetic element from human surfactant protein SP-C gene confers bronchiolar-alveolar cell specificity in transgenic mice. Am. J. Physiol. 261, L349-L356 (1991).