-
1
-
-
84974606818
-
C2c2 is a single-component programmable RNA-guided RNA-targeting CRISPR effector
-
Abudayyeh, O. O., Gootenberg, J. S., Konermann, S., Joung, J., Slaymaker, I. M., Cox, D. B., … Zhang, F. (2016). C2c2 is a single-component programmable RNA-guided RNA-targeting CRISPR effector. Science, 353, aaf5573.
-
(2016)
Science
, vol.353
, pp. aaf5573
-
-
Abudayyeh, O.O.1
Gootenberg, J.S.2
Konermann, S.3
Joung, J.4
Slaymaker, I.M.5
Cox, D.B.6
Zhang, F.7
-
2
-
-
80755187812
-
CRISPR-Cas systems in bacteria and archaea: Versatile small RNAs for adaptive defense and regulation
-
Bhaya, D., Davison, M., & Barrangou, R. (2011). CRISPR-Cas systems in bacteria and archaea: Versatile small RNAs for adaptive defense and regulation. Annual Review of Genetics, 45, 273–297.
-
(2011)
Annual Review of Genetics
, vol.45
, pp. 273-297
-
-
Bhaya, D.1
Davison, M.2
Barrangou, R.3
-
3
-
-
84982099230
-
Isozygous and selectable marker-free MSTN knockout cloned pigs generated by the combined use of CRISPR/Cas9 and Cre/LoxP
-
Bi, Y., Hua, Z., Liu, X., Hua, W., Ren, H., Xiao, H., … Zheng, X. (2016). Isozygous and selectable marker-free MSTN knockout cloned pigs generated by the combined use of CRISPR/Cas9 and Cre/LoxP. Scientific Reports, 6, 31729.
-
(2016)
Scientific Reports
, vol.6
, pp. 31729
-
-
Bi, Y.1
Hua, Z.2
Liu, X.3
Hua, W.4
Ren, H.5
Xiao, H.6
Zheng, X.7
-
4
-
-
77956126894
-
Xanthomonas AvrBs3 family-type III effectors: Discovery and function
-
Boch, J., & Bonas, U. (2010). Xanthomonas AvrBs3 family-type III effectors: Discovery and function. Annual Review of Phytopathology, 48, 419–436.
-
(2010)
Annual Review of Phytopathology
, vol.48
, pp. 419-436
-
-
Boch, J.1
Bonas, U.2
-
5
-
-
72149110399
-
Breaking the Code of DNA Binding Specificity of TAL-Type III Effectors
-
Boch, J., Scholze, H., Schornack, S., Landgraf, A., Hahn, S., Kay, S., … Bonas, U. (2009). Breaking the Code of DNA Binding Specificity of TAL-Type III Effectors. Science, 326, 1509–1512.
-
(2009)
Science
, vol.326
, pp. 1509-1512
-
-
Boch, J.1
Scholze, H.2
Schornack, S.3
Landgraf, A.4
Hahn, S.5
Kay, S.6
Bonas, U.7
-
6
-
-
85014070672
-
Precision engineering for PRRSV resistance in pigs: Macrophages from genome edited pigs lacking CD163 SRCR5 domain are fully resistant to both PRRSV genotypes while maintaining biological function
-
Burkard, C., Lillico, S. G., Reid, E., Jackson, B., Mileham, A. J., Ait-Ali, T., … Archibald, A. L. (2017). Precision engineering for PRRSV resistance in pigs: Macrophages from genome edited pigs lacking CD163 SRCR5 domain are fully resistant to both PRRSV genotypes while maintaining biological function. PLoS Pathogens, 13, e1006206.
-
(2017)
PLoS Pathogens
, vol.13
-
-
Burkard, C.1
Lillico, S.G.2
Reid, E.3
Jackson, B.4
Mileham, A.J.5
Ait-Ali, T.6
Archibald, A.L.7
-
7
-
-
84964378099
-
Silencing porcine genes significantly reduces human-anti-pig cytotoxicity profiles: An alternative to direct complement regulation
-
Butler, J. R., Martens, G. R., Estrada, J. L., Reyes, L. M., Ladowski, J. M., Galli, C., … Joseph Tector, A. (2016). Silencing porcine genes significantly reduces human-anti-pig cytotoxicity profiles: An alternative to direct complement regulation. Transgenic Research, 25, 751–759.
-
(2016)
Transgenic Research
, vol.25
, pp. 751-759
-
-
Butler, J.R.1
Martens, G.R.2
Estrada, J.L.3
Reyes, L.M.4
Ladowski, J.M.5
Galli, C.6
Joseph Tector, A.7
-
8
-
-
0029967424
-
Sheep cloned by nuclear transfer from a cultured cell line
-
Campbell, K. H., McWhir, J., Ritchie, W. A., & Wilmut, I. (1996). Sheep cloned by nuclear transfer from a cultured cell line. Nature, 380, 64–66.
-
(1996)
Nature
, vol.380
, pp. 64-66
-
-
Campbell, K.H.1
McWhir, J.2
Ritchie, W.A.3
Wilmut, I.4
-
9
-
-
84969769359
-
Production of hornless dairy cattle from genome-edited cell lines
-
Carlson, D. F., Lancto, C. A., Zang, B., Kim, E. S., Walton, M., Oldeschulte, D., … Fahrenkrug, S. C. (2016). Production of hornless dairy cattle from genome-edited cell lines. Nature Biotechnology, 34, 479–481.
-
(2016)
Nature Biotechnology
, vol.34
, pp. 479-481
-
-
Carlson, D.F.1
Lancto, C.A.2
Zang, B.3
Kim, E.S.4
Walton, M.5
Oldeschulte, D.6
Fahrenkrug, S.C.7
-
10
-
-
84867911474
-
Efficient TALEN-mediated gene knockout in livestock
-
Carlson, D. F., Tan, W., Lillico, S. G., Stverakova, D., Proudfoot, C., Christian, M., … Fahrenkrug, S. C. (2012). Efficient TALEN-mediated gene knockout in livestock. Proceedings of the National Academy of Sciences, 109, 17382–17387.
-
(2012)
Proceedings of the National Academy of Sciences
, vol.109
, pp. 17382-17387
-
-
Carlson, D.F.1
Tan, W.2
Lillico, S.G.3
Stverakova, D.4
Proudfoot, C.5
Christian, M.6
Fahrenkrug, S.C.7
-
11
-
-
45749145124
-
Zinc-finger nucleases: The next generation emerges
-
Cathomen, T., & Joung, J. K. (2008). Zinc-finger nucleases: The next generation emerges. Molecular Therapy, 16, 1200–1207.
-
(2008)
Molecular Therapy
, vol.16
, pp. 1200-1207
-
-
Cathomen, T.1
Joung, J.K.2
-
12
-
-
79960064013
-
Efficient design and assembly of custom TALEN and other TAL effector-based constructs for DNA targeting
-
Cermak, T., Doyle, E. L., Christian, M., Wang, L., Zhang, Y., Schmidt, C., … Voytas, D. F. (2011). Efficient design and assembly of custom TALEN and other TAL effector-based constructs for DNA targeting. Nucleic Acids Research, 39, e82.
-
(2011)
Nucleic Acids Research
, vol.39
-
-
Cermak, T.1
Doyle, E.L.2
Christian, M.3
Wang, L.4
Zhang, Y.5
Schmidt, C.6
Voytas, D.F.7
-
13
-
-
0028919608
-
Induction of homologous recombination in mammalian chromosomes by using the I-SceI system of Saccharomyces cerevisiae
-
Choulika, A., Perrin, A., Dujon, B., & Nicolas, J. F. (1995). Induction of homologous recombination in mammalian chromosomes by using the I-SceI system of Saccharomyces cerevisiae. Molecular and Cellular Biology, 15, 1968–1973.
-
(1995)
Molecular and Cellular Biology
, vol.15
, pp. 1968-1973
-
-
Choulika, A.1
Perrin, A.2
Dujon, B.3
Nicolas, J.F.4
-
14
-
-
78951479577
-
Targeting DNA double-strand breaks with TAL effector nucleases
-
Christian, M., Cermak, T., Doyle, E., Schmidt, C., Zhang, F., Hummel, A., … Voytas, D. (2010). Targeting DNA double-strand breaks with TAL effector nucleases. Genetics, 186, 757–761.
-
(2010)
Genetics
, vol.186
, pp. 757-761
-
-
Christian, M.1
Cermak, T.2
Doyle, E.3
Schmidt, C.4
Zhang, F.5
Hummel, A.6
Voytas, D.7
-
15
-
-
84873729095
-
Multiplex genome engineering using CRISPR/Cas systems
-
Cong, L., Ran, F. A., Cox, D., Lin, S., Barretto, R., Habib, N., … Zhang, F. (2013). Multiplex genome engineering using CRISPR/Cas systems. Science, 339, 819–823.
-
(2013)
Science
, vol.339
, pp. 819-823
-
-
Cong, L.1
Ran, F.A.2
Cox, D.3
Lin, S.4
Barretto, R.5
Habib, N.6
Zhang, F.7
-
16
-
-
84930216593
-
Gene targeting by TALEN-induced homologous recombination in goats directs production of beta-lactoglobulin-free, high-human lactoferrin milk
-
Cui, C., Song, Y., Liu, J., Ge, H., Li, Q., Huang, H., … Zhang, Y. (2015). Gene targeting by TALEN-induced homologous recombination in goats directs production of beta-lactoglobulin-free, high-human lactoferrin milk. Scientific Reports, 5, 10482.
-
(2015)
Scientific Reports
, vol.5
, pp. 10482
-
-
Cui, C.1
Song, Y.2
Liu, J.3
Ge, H.4
Li, Q.5
Huang, H.6
Zhang, Y.7
-
18
-
-
0031863007
-
Analysis of gene targeting and intrachromosomal homologous recombination stimulated by genomic double-strand breaks in mouse embryonic stem cells
-
Donoho, G., Jasin, M., & Berg, P. (1998). Analysis of gene targeting and intrachromosomal homologous recombination stimulated by genomic double-strand breaks in mouse embryonic stem cells. Molecular and Cellular Biology, 18, 4070–4078.
-
(1998)
Molecular and Cellular Biology
, vol.18
, pp. 4070-4078
-
-
Donoho, G.1
Jasin, M.2
Berg, P.3
-
19
-
-
84991728709
-
Two distinct RNase activities of CRISPR-C2c2 enable guide-RNA processing and RNA detection
-
East-Seletsky, A., O'Connell, M. R., Knight, S. C., Burstein, D., Cate, J. H., Tjian, R., & Doudna, J. A. (2016). Two distinct RNase activities of CRISPR-C2c2 enable guide-RNA processing and RNA detection. Nature, 538, 270–273.
-
(2016)
Nature
, vol.538
, pp. 270-273
-
-
East-Seletsky, A.1
O'Connell, M.R.2
Knight, S.C.3
Burstein, D.4
Cate, J.H.5
Tjian, R.6
Doudna, J.A.7
-
20
-
-
0038268049
-
A novel engineered meganuclease induces homologous recombination in yeast and mammalian cells
-
Epinat, J. C., Arnould, S., Chames, P., Rochaix, P., Desfontaines, D., Puzin, C., … Lacroix, E. (2003). A novel engineered meganuclease induces homologous recombination in yeast and mammalian cells. Nucleic Acids Research, 31, 2952–2962.
-
(2003)
Nucleic Acids Research
, vol.31
, pp. 2952-2962
-
-
Epinat, J.C.1
Arnould, S.2
Chames, P.3
Rochaix, P.4
Desfontaines, D.5
Puzin, C.6
Lacroix, E.7
-
21
-
-
84893618608
-
Genetically modified pigs to model human diseases
-
Flisikowska, T., Kind, A., & Schnieke, A. (2014). Genetically modified pigs to model human diseases. Journal of Applied Genetics, 55, 53–64.
-
(2014)
Journal of Applied Genetics
, vol.55
, pp. 53-64
-
-
Flisikowska, T.1
Kind, A.2
Schnieke, A.3
-
22
-
-
84867185165
-
A porcine model of familial adenomatous polyposis
-
Flisikowska, T., Merkl, C., Landmann, M., Eser, S., Rezaei, N., Cui, X., … Schnieke, A. (2012). A porcine model of familial adenomatous polyposis. Gastroenterology, 143(1173–1175), e1171–e1177.
-
(2012)
Gastroenterology
, vol.143
, Issue.1173-1175
, pp. e1171-e1177
-
-
Flisikowska, T.1
Merkl, C.2
Landmann, M.3
Eser, S.4
Rezaei, N.5
Cui, X.6
Schnieke, A.7
-
23
-
-
84964862130
-
The CRISPR-associated DNA-cleaving enzyme Cpf1 also processes precursor CRISPR RNA
-
Fonfara, I., Richter, H., Bratovic, M., Le Rhun, A., & Charpentier, E. (2016). The CRISPR-associated DNA-cleaving enzyme Cpf1 also processes precursor CRISPR RNA. Nature, 532, 517–521.
-
(2016)
Nature
, vol.532
, pp. 517-521
-
-
Fonfara, I.1
Richter, H.2
Bratovic, M.3
Le Rhun, A.4
Charpentier, E.5
-
24
-
-
84896929630
-
Improving CRISPR-Cas nuclease specificity using truncated guide RNAs
-
Fu, Y., Sander, J. D., Reyon, D., Cascio, V. M., & Joung, J. K. (2014). Improving CRISPR-Cas nuclease specificity using truncated guide RNAs. Nature Biotechnology, 32, 279–284.
-
(2014)
Nature Biotechnology
, vol.32
, pp. 279-284
-
-
Fu, Y.1
Sander, J.D.2
Reyon, D.3
Cascio, V.M.4
Joung, J.K.5
-
25
-
-
84879264708
-
ZFN, TALEN, and CRISPR/Cas-based methods for genome engineering
-
Gaj, T., Gersbach, C. A., & Barbas, C. F. 3rd (2013). ZFN, TALEN, and CRISPR/Cas-based methods for genome engineering. Trends in Biotechnology, 31, 397–405.
-
(2013)
Trends in Biotechnology
, vol.31
, pp. 397-405
-
-
Gaj, T.1
Gersbach, C.A.2
Barbas, C.F.3
-
26
-
-
85011279013
-
Single Cas9 nickase induced generation of NRAMP1 knockin cattle with reduced off-target effects
-
Gao, Y., Wu, H., Wang, Y., Liu, X., Chen, L., Li, Q., … Zhang, Y. (2017). Single Cas9 nickase induced generation of NRAMP1 knockin cattle with reduced off-target effects. Genome Biology, 18, 13.
-
(2017)
Genome Biology
, vol.18
, pp. 13
-
-
Gao, Y.1
Wu, H.2
Wang, Y.3
Liu, X.4
Chen, L.5
Li, Q.6
Zhang, Y.7
-
27
-
-
84902210542
-
Fusion of catalytically inactive Cas9 to FokI nuclease improves the specificity of genome modification
-
Guilinger, J. P., Thompson, D. B., & Liu, D. R. (2014). Fusion of catalytically inactive Cas9 to FokI nuclease improves the specificity of genome modification. Nature Biotechnology, 32, 577–582.
-
(2014)
Nature Biotechnology
, vol.32
, pp. 577-582
-
-
Guilinger, J.P.1
Thompson, D.B.2
Liu, D.R.3
-
28
-
-
84978716213
-
Generation and evaluation of Myostatin knock-out rabbits and goats using CRISPR/Cas9 system
-
Guo, R. H., Wan, Y. J., Xu, D., Cui, L. B., Deng, M. T., Zhang, G. M., … Zhang, Y. L. (2016). Generation and evaluation of Myostatin knock-out rabbits and goats using CRISPR/Cas9 system. Scientific Reports, 6, 29855.
-
(2016)
Scientific Reports
, vol.6
, pp. 29855
-
-
Guo, R.H.1
Wan, Y.J.2
Xu, D.3
Cui, L.B.4
Deng, M.T.5
Zhang, G.M.6
Zhang, Y.L.7
-
29
-
-
57849128497
-
Nuclear reprogramming in cells
-
Gurdon, J. B., & Melton, D. A. (2008). Nuclear reprogramming in cells. Science, 322, 1811–1815.
-
(2008)
Science
, vol.322
, pp. 1811-1815
-
-
Gurdon, J.B.1
Melton, D.A.2
-
30
-
-
84897594300
-
One-step generation of knockout pigs by zygote injection of CRISPR/Cas system
-
Hai, T., Teng, F., Guo, R., Li, W., & Zhou, Q. (2014). One-step generation of knockout pigs by zygote injection of CRISPR/Cas system. Cell Research, 24, 372–375.
-
(2014)
Cell Research
, vol.24
, pp. 372-375
-
-
Hai, T.1
Teng, F.2
Guo, R.3
Li, W.4
Zhou, Q.5
-
31
-
-
79961079857
-
Efficient generation of a biallelic knockout in pigs using zinc-finger nucleases
-
Hauschild, J., Petersen, B., Santiago, Y., Queisser, A. L., Carnwath, J. W., Lucas-Hahn, A., … Niemann, H. (2011). Efficient generation of a biallelic knockout in pigs using zinc-finger nucleases. Proceedings of the National Academy of Sciences, 108, 12013–12017.
-
(2011)
Proceedings of the National Academy of Sciences
, vol.108
, pp. 12013-12017
-
-
Hauschild, J.1
Petersen, B.2
Santiago, Y.3
Queisser, A.L.4
Carnwath, J.W.5
Lucas-Hahn, A.6
Niemann, H.7
-
32
-
-
79960836456
-
Genetic engineering of human pluripotent cells using TALE nucleases
-
Hockemeyer, D., Wang, H., Kiani, S., Lai, C. S., Gao, Q., Cassady, J. P., … Jaenisch, R. (2011). Genetic engineering of human pluripotent cells using TALE nucleases. Nature Biotechnology, 29, 731–734.
-
(2011)
Nature Biotechnology
, vol.29
, pp. 731-734
-
-
Hockemeyer, D.1
Wang, H.2
Kiani, S.3
Lai, C.S.4
Gao, Q.5
Cassady, J.P.6
Jaenisch, R.7
-
33
-
-
79961185942
-
Heritable gene targeting in zebrafish using customized TALENs
-
Huang, P., Xiao, A., Zhou, M., Zhu, Z., Lin, S., & Zhang, B. (2011). Heritable gene targeting in zebrafish using customized TALENs. Nature Biotechnology, 29, 699–700.
-
(2011)
Nature Biotechnology
, vol.29
, pp. 699-700
-
-
Huang, P.1
Xiao, A.2
Zhou, M.3
Zhu, Z.4
Lin, S.5
Zhang, B.6
-
34
-
-
84876567971
-
RNA-programmed genome editing in human cells
-
Jinek, M., East, A., Cheng, A., Lin, S., Ma, E., & Doudna, J. (2013). RNA-programmed genome editing in human cells. Elife, 2, e00471.
-
(2013)
Elife
, vol.2
-
-
Jinek, M.1
East, A.2
Cheng, A.3
Lin, S.4
Ma, E.5
Doudna, J.6
-
35
-
-
0030032063
-
Hybrid restriction enzymes: Zinc finger fusions to Fok I cleavage domain
-
Kim, Y. G., Cha, J., & Chandrasegaran, S. (1996). Hybrid restriction enzymes: Zinc finger fusions to Fok I cleavage domain. Proceedings of the National Academy of Sciences, 93, 1156–1160.
-
(1996)
Proceedings of the National Academy of Sciences
, vol.93
, pp. 1156-1160
-
-
Kim, Y.G.1
Cha, J.2
Chandrasegaran, S.3
-
36
-
-
84875157258
-
A library of TAL effector nucleases spanning the human genome
-
Kim, Y., Kweon, J., Kim, A., Chon, J. K., Yoo, J. Y., Kim, H. J., … Kim, J. S. (2013). A library of TAL effector nucleases spanning the human genome. Nature Biotechnology, 31, 251–258.
-
(2013)
Nature Biotechnology
, vol.31
, pp. 251-258
-
-
Kim, Y.1
Kweon, J.2
Kim, A.3
Chon, J.K.4
Yoo, J.Y.5
Kim, H.J.6
Kim, J.S.7
-
37
-
-
85018918215
-
Highly efficient RNA-guided base editing in mouse embryos
-
Kim, K., Ryu, S. M., Kim, S. T., Baek, G., Kim, D., Lim, K., … Kim, J. S. (2017). Highly efficient RNA-guided base editing in mouse embryos. Nature Biotechnology, 35, 435–437.
-
(2017)
Nature Biotechnology
, vol.35
, pp. 435-437
-
-
Kim, K.1
Ryu, S.M.2
Kim, S.T.3
Baek, G.4
Kim, D.5
Lim, K.6
Kim, J.S.7
-
38
-
-
0038947196
-
Site-specific cleavage of DNA-RNA hybrids by zinc finger/FokI cleavage domain fusions
-
Kim, Y. G., Shi, Y., Berg, J. M., & Chandrasegaran, S. (1997). Site-specific cleavage of DNA-RNA hybrids by zinc finger/FokI cleavage domain fusions. Gene, 203, 43–49.
-
(1997)
Gene
, vol.203
, pp. 43-49
-
-
Kim, Y.G.1
Shi, Y.2
Berg, J.M.3
Chandrasegaran, S.4
-
39
-
-
84963941043
-
High-fidelity CRISPR-Cas9 nucleases with no detectable genome-wide off-target effects
-
Kleinstiver, B. P., Pattanayak, V., Prew, M. S., Tsai, S. Q., Nguyen, N. T., & Zheng, Z. (2016). High-fidelity CRISPR-Cas9 nucleases with no detectable genome-wide off-target effects. Nature, 529, 490–495.
-
(2016)
Nature
, vol.529
, pp. 490-495
-
-
Kleinstiver, B.P.1
Pattanayak, V.2
Prew, M.S.3
Tsai, S.Q.4
Nguyen, N.T.5
Zheng, Z.6
-
40
-
-
84963941043
-
High-fidelity CRISPR-Cas9 nucleases with no detectable genome-wide off-target effects
-
Kleinstiver, B. P., Pattanayak, V., Prew, M. S., Tsai, S. Q., Nguyen, N. T., Zheng, Z., & Joung, J. K. (2016). High-fidelity CRISPR-Cas9 nucleases with no detectable genome-wide off-target effects. Nature, 529, 490–495.
-
(2016)
Nature
, vol.529
, pp. 490-495
-
-
Kleinstiver, B.P.1
Pattanayak, V.2
Prew, M.S.3
Tsai, S.Q.4
Nguyen, N.T.5
Zheng, Z.6
Joung, J.K.7
-
41
-
-
84981347695
-
Genome-wide specificities of CRISPR-Cas Cpf1 nucleases in human cells
-
Kleinstiver, B. P., Tsai, S. Q., Prew, M. S., Nguyen, N. T., Welch, M. M., Lopez, J. M., … Joung, J. K. (2016). Genome-wide specificities of CRISPR-Cas Cpf1 nucleases in human cells. Nature Biotechnology, 34, 869–874.
-
(2016)
Nature Biotechnology
, vol.34
, pp. 869-874
-
-
Kleinstiver, B.P.1
Tsai, S.Q.2
Prew, M.S.3
Nguyen, N.T.4
Welch, M.M.5
Lopez, J.M.6
Joung, J.K.7
-
42
-
-
84885723361
-
Dystrophin-deficient pigs provide new insights into the hierarchy of physiological derangements of dystrophic muscle
-
Klymiuk, N., Blutke, A., Graf, A., Krause, S., Burkhardt, K., Wuensch, A., … Wolf, E. (2013). Dystrophin-deficient pigs provide new insights into the hierarchy of physiological derangements of dystrophic muscle. Human Molecular Genetics, 22, 4368–4382.
-
(2013)
Human Molecular Genetics
, vol.22
, pp. 4368-4382
-
-
Klymiuk, N.1
Blutke, A.2
Graf, A.3
Krause, S.4
Burkhardt, K.5
Wuensch, A.6
Wolf, E.7
-
43
-
-
84971006562
-
Programmable editing of a target base in genomic DNA without double-stranded DNA cleavage
-
Komor, A. C., Kim, Y. B., Packer, M. S., Zuris, J. A., & Liu, D. R. (2016). Programmable editing of a target base in genomic DNA without double-stranded DNA cleavage. Nature, 533, 420–424.
-
(2016)
Nature
, vol.533
, pp. 420-424
-
-
Komor, A.C.1
Kim, Y.B.2
Packer, M.S.3
Zuris, J.A.4
Liu, D.R.5
-
44
-
-
78651270582
-
TAL nucleases (TALNs): Hybrid proteins composed of TAL effectors and FokI DNA-cleavage domain
-
Li, T., Huang, S., Jiang, W. Z., Wright, D., Spalding, M. H., Weeks, D. P., & Yang, B. (2011). TAL nucleases (TALNs): Hybrid proteins composed of TAL effectors and FokI DNA-cleavage domain. Nucleic Acids Research, 39, 359–372.
-
(2011)
Nucleic Acids Research
, vol.39
, pp. 359-372
-
-
Li, T.1
Huang, S.2
Jiang, W.Z.3
Wright, D.4
Spalding, M.H.5
Weeks, D.P.6
Yang, B.7
-
45
-
-
79960034141
-
Modularly assembled designer TAL effector nucleases for targeted gene knockout and gene replacement in eukaryotes
-
Li, T., Huang, S., Zhao, X., Wright, D. A., Carpenter, S., Spalding, M. H., … Yang, B. (2011). Modularly assembled designer TAL effector nucleases for targeted gene knockout and gene replacement in eukaryotes. Nucleic Acids Research, 39, 6315–6325.
-
(2011)
Nucleic Acids Research
, vol.39
, pp. 6315-6325
-
-
Li, T.1
Huang, S.2
Zhao, X.3
Wright, D.A.4
Carpenter, S.5
Spalding, M.H.6
Yang, B.7
-
46
-
-
84899683227
-
Efficient generation of myostatin (MSTN) biallelic mutations in cattle using zinc finger nucleases
-
Luo, J., Song, Z., Yu, S., Cui, D., Wang, B., Ding, F., … Li, N. (2014). Efficient generation of myostatin (MSTN) biallelic mutations in cattle using zinc finger nucleases. PLoS One, 9, e95225.
-
(2014)
PLoS One
, vol.9
-
-
Luo, J.1
Song, Z.2
Yu, S.3
Cui, D.4
Wang, B.5
Ding, F.6
Li, N.7
-
47
-
-
79952302385
-
De novo-engineered transcription activator-like effector (TALE) hybrid nuclease with novel DNA binding specificity creates double-strand breaks
-
Mahfouz, M. M., Li, L., Shamimuzzaman, M., Wibowo, A., Fang, X., & Zhu, J. K. (2011). De novo-engineered transcription activator-like effector (TALE) hybrid nuclease with novel DNA binding specificity creates double-strand breaks. Proceedings of the National Academy of Sciences, 108, 2623–2628.
-
(2011)
Proceedings of the National Academy of Sciences
, vol.108
, pp. 2623-2628
-
-
Mahfouz, M.M.1
Li, L.2
Shamimuzzaman, M.3
Wibowo, A.4
Fang, X.5
Zhu, J.K.6
-
48
-
-
84873734105
-
RNA-guided human genome engineering via Cas9
-
Mali, P., Yang, L., Esvelt, K. M., Aach, J., Guell, M., DiCarlo, J. E., … Church, G. M. (2013). RNA-guided human genome engineering via Cas9. Science, 339, 823–826.
-
(2013)
Science
, vol.339
, pp. 823-826
-
-
Mali, P.1
Yang, L.2
Esvelt, K.M.3
Aach, J.4
Guell, M.5
DiCarlo, J.E.6
Church, G.M.7
-
49
-
-
0040215628
-
Repetitive zinc-binding domains in the protein transcription factor IIIA from Xenopus oocytes
-
Miller, J., McLachlan, A. D., & Klug, A. (1985). Repetitive zinc-binding domains in the protein transcription factor IIIA from Xenopus oocytes. EMBO Journal, 4, 1609–1614.
-
(1985)
EMBO Journal
, vol.4
, pp. 1609-1614
-
-
Miller, J.1
McLachlan, A.D.2
Klug, A.3
-
50
-
-
79551685675
-
A TALE nuclease architecture for efficient genome editing
-
Miller, J. C., Tan, S., Qiao, G., Barlow, K. A., Wang, J., Xia, D. F., … Rebar, E. J. (2011). A TALE nuclease architecture for efficient genome editing. Nature Biotechnology, 29, 143–148.
-
(2011)
Nature Biotechnology
, vol.29
, pp. 143-148
-
-
Miller, J.C.1
Tan, S.2
Qiao, G.3
Barlow, K.A.4
Wang, J.5
Xia, D.F.6
Rebar, E.J.7
-
51
-
-
72149090954
-
A simple cipher governs DNA recognition by TAL effectors
-
Moscou, M. J., & Bogdanove, A. J. (2009). A simple cipher governs DNA recognition by TAL effectors. Science, 326, 1501–1501.
-
(2009)
Science
, vol.326
, pp. 1501
-
-
Moscou, M.J.1
Bogdanove, A.J.2
-
52
-
-
84907062671
-
Efficient gene knockout in goats using CRISPR/Cas9 system
-
Ni, W., Qiao, J., Hu, S., Zhao, X., Regouski, M., Yang, M., … Chen, C. (2014). Efficient gene knockout in goats using CRISPR/Cas9 system. PLoS One, 9, e106718.
-
(2014)
PLoS One
, vol.9
-
-
Ni, W.1
Qiao, J.2
Hu, S.3
Zhao, X.4
Regouski, M.5
Yang, M.6
Chen, C.7
-
53
-
-
84963682304
-
Targeted mutagenesis in chicken using CRISPR/Cas9 system
-
Oishi, I., Yoshii, K., Miyahara, D., Kagami, H., & Tagami, T. (2016). Targeted mutagenesis in chicken using CRISPR/Cas9 system. Scientific Reports, 6, 23980.
-
(2016)
Scientific Reports
, vol.6
, pp. 23980
-
-
Oishi, I.1
Yoshii, K.2
Miyahara, D.3
Kagami, H.4
Tagami, T.5
-
54
-
-
0034923498
-
Design and selection of novel Cys2His2 zinc finger proteins
-
Pabo, C. O., Peisach, E., & Grant, R. A. (2001). Design and selection of novel Cys2His2 zinc finger proteins. Annual Review of Biochemistry, 70, 313–340.
-
(2001)
Annual Review of Biochemistry
, vol.70
, pp. 313-340
-
-
Pabo, C.O.1
Peisach, E.2
Grant, R.A.3
-
55
-
-
85009192924
-
Generation of germline ablated male pigs by CRISPR/Cas9 editing of the NANOS2 gene
-
Park, K. E., Kaucher, A. V., Powell, A., Waqas, M. S., Sandmaier, S. E., Oatley, M. J., … Oatley, J. M. (2017). Generation of germline ablated male pigs by CRISPR/Cas9 editing of the NANOS2 gene. Scientific Reports, 7, 40176.
-
(2017)
Scientific Reports
, vol.7
, pp. 40176
-
-
Park, K.E.1
Kaucher, A.V.2
Powell, A.3
Waqas, M.S.4
Sandmaier, S.E.5
Oatley, M.J.6
Oatley, J.M.7
-
56
-
-
0025773296
-
Zinc finger-DNA recognition: Crystal structure of a Zif268-DNA complex at 2.1 A
-
Pavletich, N. P., & Pabo, C. O. (1991). Zinc finger-DNA recognition: Crystal structure of a Zif268-DNA complex at 2.1 A. Science, 252, 809–817.
-
(1991)
Science
, vol.252
, pp. 809-817
-
-
Pavletich, N.P.1
Pabo, C.O.2
-
57
-
-
84988470736
-
Efficient production of biallelic GGTA1 knockout pigs by cytoplasmic microinjection of CRISPR/Cas9 into zygotes
-
Petersen, B., Frenzel, A., Lucas-Hahn, A., Herrmann, D., Hassel, P., Klein, S., … Niemann, H. (2016). Efficient production of biallelic GGTA1 knockout pigs by cytoplasmic microinjection of CRISPR/Cas9 into zygotes. Xenotransplantation, 23, 338–346.
-
(2016)
Xenotransplantation
, vol.23
, pp. 338-346
-
-
Petersen, B.1
Frenzel, A.2
Lucas-Hahn, A.3
Herrmann, D.4
Hassel, P.5
Klein, S.6
Niemann, H.7
-
58
-
-
51349092848
-
Development and validation of a highly efficient protocol of porcine somatic cloning using preovulatory embryo transfer in peripubertal gilts
-
Petersen, B., Lucas-Hahn, A., Oropeza, M., Hornen, N., Lemme, E., Hassel, P., … Niemann, H. (2008). Development and validation of a highly efficient protocol of porcine somatic cloning using preovulatory embryo transfer in peripubertal gilts. Cloning and Stem Cells, 10, 355–362.
-
(2008)
Cloning and Stem Cells
, vol.10
, pp. 355-362
-
-
Petersen, B.1
Lucas-Hahn, A.2
Oropeza, M.3
Hornen, N.4
Lemme, E.5
Hassel, P.6
Niemann, H.7
-
59
-
-
84919951002
-
Genome edited sheep and cattle
-
Proudfoot, C., Carlson, D. F., Huddart, R., Long, C. R., Pryor, J. H., King, T. J., … Fahrenkrug, S. C. (2015). Genome edited sheep and cattle. Transgenic Research, 24, 147–153.
-
(2015)
Transgenic Research
, vol.24
, pp. 147-153
-
-
Proudfoot, C.1
Carlson, D.F.2
Huddart, R.3
Long, C.R.4
Pryor, J.H.5
King, T.J.6
Fahrenkrug, S.C.7
-
60
-
-
84942134094
-
Targeted mutations in myostatin by zinc-finger nucleases result in double-muscled phenotype in Meishan pigs
-
Qian, L., Tang, M., Yang, J., Wang, Q., Cai, C., Jiang, S., … Cui, W. (2015). Targeted mutations in myostatin by zinc-finger nucleases result in double-muscled phenotype in Meishan pigs. Scientific Reports, 5, 14435.
-
(2015)
Scientific Reports
, vol.5
, pp. 14435
-
-
Qian, L.1
Tang, M.2
Yang, J.3
Wang, Q.4
Cai, C.5
Jiang, S.6
Cui, W.7
-
61
-
-
84912569481
-
Creating class I MHC-null pigs using guide RNA and the Cas9 endonuclease
-
Reyes, L. M., Estrada, J. L., Wang, Z. Y., Blosser, R. J., Smith, R. F., Sidner, R. A., … Tector, A. J. (2014). Creating class I MHC-null pigs using guide RNA and the Cas9 endonuclease. Journal of Immunology, 193, 5751–5757.
-
(2014)
Journal of Immunology
, vol.193
, pp. 5751-5757
-
-
Reyes, L.M.1
Estrada, J.L.2
Wang, Z.Y.3
Blosser, R.J.4
Smith, R.F.5
Sidner, R.A.6
Tector, A.J.7
-
62
-
-
0028237305
-
Expression of a site-specific endonuclease stimulates homologous recombination in mammalian cells
-
Rouet, P., Smih, F., & Jasin, M. (1994a). Expression of a site-specific endonuclease stimulates homologous recombination in mammalian cells. Proceedings of the National Academy of Sciences, 91, 6064–6068.
-
(1994)
Proceedings of the National Academy of Sciences
, vol.91
, pp. 6064-6068
-
-
Rouet, P.1
Smih, F.2
Jasin, M.3
-
63
-
-
0028061666
-
Introduction of double-strand breaks into the genome of mouse cells by expression of a rare-cutting endonuclease
-
Rouet, P., Smih, F., & Jasin, M. (1994b). Introduction of double-strand breaks into the genome of mouse cells by expression of a rare-cutting endonuclease. Molecular and Cellular Biology, 14, 8096–8106.
-
(1994)
Molecular and Cellular Biology
, vol.14
, pp. 8096-8106
-
-
Rouet, P.1
Smih, F.2
Jasin, M.3
-
64
-
-
79961192836
-
Targeted gene disruption in somatic zebrafish cells using engineered TALENs
-
Sander, J. D., Cade, L., Khayter, C., Reyon, D., Peterson, R. T., Joung, J. K., & Yeh, J. R. (2011). Targeted gene disruption in somatic zebrafish cells using engineered TALENs. Nature Biotechnology, 29, 697–698.
-
(2011)
Nature Biotechnology
, vol.29
, pp. 697-698
-
-
Sander, J.D.1
Cade, L.2
Khayter, C.3
Reyon, D.4
Peterson, R.T.5
Joung, J.K.6
Yeh, J.R.7
-
65
-
-
84897954175
-
Efficient genome modification by CRISPR-Cas9 nickase with minimal off-target effects
-
Shen, B., Zhang, W., Zhang, J., Zhou, J., Wang, J., Chen, L., … Skarnes, W. C. (2014). Efficient genome modification by CRISPR-Cas9 nickase with minimal off-target effects. Nature Methods, 11, 399–402.
-
(2014)
Nature Methods
, vol.11
, pp. 399-402
-
-
Shen, B.1
Zhang, W.2
Zhang, J.3
Zhou, J.4
Wang, J.5
Chen, L.6
Skarnes, W.C.7
-
66
-
-
84947736727
-
Discovery and functional characterization of diverse class 2 CRISPR-Cas systems
-
Shmakov, S., Abudayyeh, O. O., Makarova, K. S., Wolf, Y. I., Gootenberg, J. S., Semenova, E., … Koonin, E. V. (2015). Discovery and functional characterization of diverse class 2 CRISPR-Cas systems. Molecular Cell, 60, 385–397.
-
(2015)
Molecular Cell
, vol.60
, pp. 385-397
-
-
Shmakov, S.1
Abudayyeh, O.O.2
Makarova, K.S.3
Wolf, Y.I.4
Gootenberg, J.S.5
Semenova, E.6
Koonin, E.V.7
-
67
-
-
84952943845
-
Rationally engineered Cas9 nucleases with improved specificity
-
Slaymaker, I. M., Gao, L., Zetsche, B., Scott, D. A., Yan, W. X., & Zhang, F. (2016). Rationally engineered Cas9 nucleases with improved specificity. Science, 351, 84–88.
-
(2016)
Science
, vol.351
, pp. 84-88
-
-
Slaymaker, I.M.1
Gao, L.2
Zetsche, B.3
Scott, D.A.4
Yan, W.X.5
Zhang, F.6
-
68
-
-
0034283804
-
Requirements for double-strand cleavage by chimeric restriction enzymes with zinc finger DNA-recognition domains
-
Smith, J., Bibikova, M., Whitby, F. G., Reddy, A. R., Chandrasegaran, S., & Carroll, D. (2000). Requirements for double-strand cleavage by chimeric restriction enzymes with zinc finger DNA-recognition domains. Nucleic Acids Research, 28, 3361–3369.
-
(2000)
Nucleic Acids Research
, vol.28
, pp. 3361-3369
-
-
Smith, J.1
Bibikova, M.2
Whitby, F.G.3
Reddy, A.R.4
Chandrasegaran, S.5
Carroll, D.6
-
69
-
-
84928397982
-
Expression, purification and characterization of zinc-finger nuclease to knockout the goat beta-lactoglobulin gene
-
Song, Y., Cui, C., Zhu, H., Li, Q., Zhao, F., & Jin, Y. (2015). Expression, purification and characterization of zinc-finger nuclease to knockout the goat beta-lactoglobulin gene. Protein Expression and Purification, 112, 1–7.
-
(2015)
Protein Expression and Purification
, vol.112
, pp. 1-7
-
-
Song, Y.1
Cui, C.2
Zhu, H.3
Li, Q.4
Zhao, F.5
Jin, Y.6
-
70
-
-
34447323568
-
Structure-based redesign of the dimerization interface reduces the toxicity of zinc-finger nucleases
-
Szczepek, M., Brondani, V., Buchel, J., Serrano, L., Segal, D. J., & Cathomen, T. (2007). Structure-based redesign of the dimerization interface reduces the toxicity of zinc-finger nucleases. Nature Biotechnology, 25, 786–793.
-
(2007)
Nature Biotechnology
, vol.25
, pp. 786-793
-
-
Szczepek, M.1
Brondani, V.2
Buchel, J.3
Serrano, L.4
Segal, D.J.5
Cathomen, T.6
-
71
-
-
84885358161
-
Efficient nonmeiotic allele introgression in livestock using custom endonucleases
-
Tan, W., Carlson, D. F., Lancto, C. A., Garbe, J. R., Webster, D. A., Hackett, P. B., & Fahrenkrug, S. C. (2013). Efficient nonmeiotic allele introgression in livestock using custom endonucleases. Proceedings of the National Academy of Sciences, 110, 16526–16531.
-
(2013)
Proceedings of the National Academy of Sciences
, vol.110
, pp. 16526-16531
-
-
Tan, W.1
Carlson, D.F.2
Lancto, C.A.3
Garbe, J.R.4
Webster, D.A.5
Hackett, P.B.6
Fahrenkrug, S.C.7
-
72
-
-
84957548929
-
Gene targeting, genome editing: From Dolly to editors
-
Tan, W., Proudfoot, C., Lillico, S. G., & Whitelaw, C. B. (2016). Gene targeting, genome editing: From Dolly to editors. Transgenic Research, 25, 273–287.
-
(2016)
Transgenic Research
, vol.25
, pp. 273-287
-
-
Tan, W.1
Proudfoot, C.2
Lillico, S.G.3
Whitelaw, C.B.4
-
74
-
-
79961196358
-
Knockout rats generated by embryo microinjection of TALENs
-
Tesson, L., Usal, C., Menoret, S., Leung, E., Niles, B. J., Remy, S., … Cost, G. J. (2011). Knockout rats generated by embryo microinjection of TALENs. Nature Biotechnology, 29, 695–696.
-
(2011)
Nature Biotechnology
, vol.29
, pp. 695-696
-
-
Tesson, L.1
Usal, C.2
Menoret, S.3
Leung, E.4
Niles, B.J.5
Remy, S.6
Cost, G.J.7
-
75
-
-
84902204289
-
Dimeric CRISPR RNA-guided FokI nucleases for highly specific genome editing
-
Tsai, S. Q., Wyvekens, N., Khayter, C., Foden, J. A., Thapar, V., Reyon, D., … Joung, J. K. (2014). Dimeric CRISPR RNA-guided FokI nucleases for highly specific genome editing. Nature Biotechnology, 32, 569–576.
-
(2014)
Nature Biotechnology
, vol.32
, pp. 569-576
-
-
Tsai, S.Q.1
Wyvekens, N.2
Khayter, C.3
Foden, J.A.4
Thapar, V.5
Reyon, D.6
Joung, J.K.7
-
76
-
-
0035902445
-
Manipulating the mammalian genome by homologous recombination
-
Vasquez, K. M., Marburger, K., Intody, Z., & Wilson, J. H. (2001). Manipulating the mammalian genome by homologous recombination. Proceedings of the National Academy of Sciences, 98, 8403–8410.
-
(2001)
Proceedings of the National Academy of Sciences
, vol.98
, pp. 8403-8410
-
-
Vasquez, K.M.1
Marburger, K.2
Intody, Z.3
Wilson, J.H.4
-
77
-
-
72149111192
-
Plant scienc. DNA binding made easy
-
Voytas, D. F., & Joung, J. K. (2009). Plant scienc. DNA binding made easy. Science, 326, 1491–1492.
-
(2009)
Science
, vol.326
, pp. 1491-1492
-
-
Voytas, D.F.1
Joung, J.K.2
-
78
-
-
85006373186
-
Efficient generation of B2 m-null pigs via injection of zygote with TALENs
-
Wang, Y., Du, Y., Zhou, X., Wang, L., Li, J., Wang, F., … Wei, H. (2016). Efficient generation of B2 m-null pigs via injection of zygote with TALENs. Scientific Reports, 6, 38854.
-
(2016)
Scientific Reports
, vol.6
, pp. 38854
-
-
Wang, Y.1
Du, Y.2
Zhou, X.3
Wang, L.4
Li, J.5
Wang, F.6
Wei, H.7
-
79
-
-
84941206117
-
Generation of gene-modified goats targeting MSTN and FGF5 via zygote injection of CRISPR/Cas9 system
-
Wang, X., Yu, H., Lei, A., Zhou, J., Zeng, W., Zhu, H., … Chen, Y. (2015). Generation of gene-modified goats targeting MSTN and FGF5 via zygote injection of CRISPR/Cas9 system. Scientific Reports, 5, 13878.
-
(2015)
Scientific Reports
, vol.5
, pp. 13878
-
-
Wang, X.1
Yu, H.2
Lei, A.3
Zhou, J.4
Zeng, W.5
Zhu, H.6
Chen, Y.7
-
80
-
-
78049251841
-
Knockout of exogenous EGFP gene in porcine somatic cells using zinc-finger nucleases
-
Watanabe, M., Umeyama, K., Matsunari, H., Takayanagi, S., Haruyama, E., Nakano, K., … Nagashima, H. (2010). Knockout of exogenous EGFP gene in porcine somatic cells using zinc-finger nucleases. Biochemical and Biophysical Research Communications, 402, 14–18.
-
(2010)
Biochemical and Biophysical Research Communications
, vol.402
, pp. 14-18
-
-
Watanabe, M.1
Umeyama, K.2
Matsunari, H.3
Takayanagi, S.4
Haruyama, E.5
Nakano, K.6
Nagashima, H.7
-
81
-
-
85020285841
-
Genome-editing technologies to improve research, reproduction, and production in pigs
-
Wells, K. D., & Prather, R. S. (2017). Genome-editing technologies to improve research, reproduction, and production in pigs. Molecular Reproduction and Development, doi: https://doi.org/10.1002/mrd.22812.
-
(2017)
Molecular Reproduction and Development
-
-
Wells, K.D.1
Prather, R.S.2
-
82
-
-
84953776513
-
Gene-edited pigs are protected from porcine reproductive and respiratory syndrome virus
-
Whitworth, K. M., Rowland, R. R., Ewen, C. L., Trible, B. R., Kerrigan, M. A., Cino-Ozuna, A. G., … Prather, R. S. (2016). Gene-edited pigs are protected from porcine reproductive and respiratory syndrome virus. Nature Biotechnology, 34, 20–22.
-
(2016)
Nature Biotechnology
, vol.34
, pp. 20-22
-
-
Whitworth, K.M.1
Rowland, R.R.2
Ewen, C.L.3
Trible, B.R.4
Kerrigan, M.A.5
Cino-Ozuna, A.G.6
Prather, R.S.7
-
83
-
-
79251529218
-
Gene targeting with zinc finger nucleases to produce cloned eGFP knockout pigs
-
Whyte, J. J., Zhao, J., Wells, K. D., Samuel, M. S., Whitworth, K. M., Walters, E. M., … Prather, R. S. (2011). Gene targeting with zinc finger nucleases to produce cloned eGFP knockout pigs. Molecular Reproduction and Development, 78, 2.
-
(2011)
Molecular Reproduction and Development
, vol.78
, pp. 2
-
-
Whyte, J.J.1
Zhao, J.2
Wells, K.D.3
Samuel, M.S.4
Whitworth, K.M.5
Walters, E.M.6
Prather, R.S.7
-
84
-
-
84857097177
-
RNA-guided genetic silencing systems in bacteria and archaea
-
Wiedenheft, B., Sternberg, S. H., & Doudna, J. A. (2012). RNA-guided genetic silencing systems in bacteria and archaea. Nature, 482, 331–338.
-
(2012)
Nature
, vol.482
, pp. 331-338
-
-
Wiedenheft, B.1
Sternberg, S.H.2
Doudna, J.A.3
-
85
-
-
0037057695
-
Somatic cell nuclear transfer
-
Wilmut, I., Beaujean, N., de Sousa, P. A., Dinnyes, A., King, T. J., Paterson, L. A., … Young, L. E. (2002). Somatic cell nuclear transfer. Nature, 419, 583–586.
-
(2002)
Nature
, vol.419
, pp. 583-586
-
-
Wilmut, I.1
Beaujean, N.2
de Sousa, P.A.3
Dinnyes, A.4
King, T.J.5
Paterson, L.A.6
Young, L.E.7
-
86
-
-
84961290146
-
TALE nickase-mediated SP110 knockin endows cattle with increased resistance to tuberculosis
-
Wu, H., Wang, Y., Zhang, Y., Yang, M., Lv, J., Liu, J., & Zhang, Y. (2015). TALE nickase-mediated SP110 knockin endows cattle with increased resistance to tuberculosis. Proceedings of the National Academy of Sciences, 112, E1530–E1539.
-
(2015)
Proceedings of the National Academy of Sciences
, vol.112
, pp. E1530-E1539
-
-
Wu, H.1
Wang, Y.2
Zhang, Y.3
Yang, M.4
Lv, J.5
Liu, J.6
Zhang, Y.7
-
87
-
-
84879419797
-
Targeted editing of goat genome with modular-assembly zinc finger nucleases based on activity prediction by computational molecular modeling
-
Xiong, K., Li, S., Zhang, H., Cui, Y., Yu, D., Li, Y., … Chen, J. (2013). Targeted editing of goat genome with modular-assembly zinc finger nucleases based on activity prediction by computational molecular modeling. Molecular Biology Reports, 40, 4251–4256.
-
(2013)
Molecular Biology Reports
, vol.40
, pp. 4251-4256
-
-
Xiong, K.1
Li, S.2
Zhang, H.3
Cui, Y.4
Yu, D.5
Li, Y.6
Chen, J.7
-
88
-
-
84948447883
-
Genome-wide inactivation of porcine endogenous retroviruses (PERVs)
-
Yang, L., Guell, M., Niu, D., George, H., Lesha, E., Grishin, D., … Church, G. (2015). Genome-wide inactivation of porcine endogenous retroviruses (PERVs). Science, 350, 1101–1104.
-
(2015)
Science
, vol.350
, pp. 1101-1104
-
-
Yang, L.1
Guell, M.2
Niu, D.3
George, H.4
Lesha, E.5
Grishin, D.6
Church, G.7
-
89
-
-
33847275530
-
Nuclear reprogramming of cloned embryos and its implications for therapeutic cloning
-
Yang, X., Smith, S. L., Tian, X. C., Lewin, H. A., Renard, J. P., & Wakayama, T. (2007). Nuclear reprogramming of cloned embryos and its implications for therapeutic cloning. Nature Genetics, 39, 295–302.
-
(2007)
Nature Genetics
, vol.39
, pp. 295-302
-
-
Yang, X.1
Smith, S.L.2
Tian, X.C.3
Lewin, H.A.4
Renard, J.P.5
Wakayama, T.6
-
90
-
-
85027921901
-
Generation of PPARgamma mono-allelic knockout pigs via zinc-finger nucleases and nuclear transfer cloning
-
Yang, D., Yang, H., Li, W., Zhao, B., Ouyang, Z., Liu, Z., … Lai, L. (2011). Generation of PPARgamma mono-allelic knockout pigs via zinc-finger nucleases and nuclear transfer cloning. Cell Research, 21, 979–982.
-
(2011)
Cell Research
, vol.21
, pp. 979-982
-
-
Yang, D.1
Yang, H.2
Li, W.3
Zhao, B.4
Ouyang, Z.5
Liu, Z.6
Lai, L.7
-
91
-
-
84979497664
-
Efficient TALEN-mediated myostatin gene editing in goats
-
Yu, B. L., Lu, R., Yuan, Y. G., Zhang, T., Song, S. Z., Qi, Z. Q., … Cheng, Y. (2016). Efficient TALEN-mediated myostatin gene editing in goats. BMC Developmental Biology, 16, 26.
-
(2016)
BMC Developmental Biology
, vol.16
, pp. 26
-
-
Yu, B.L.1
Lu, R.2
Yuan, Y.G.3
Zhang, T.4
Song, S.Z.5
Qi, Z.Q.6
Cheng, Y.7
-
92
-
-
80555150663
-
Highly efficient modification of beta-lactoglobulin (BLG) gene via zinc-finger nucleases in cattle
-
Yu, S., Luo, J., Song, Z., Ding, F., Dai, Y., & Li, N. (2011). Highly efficient modification of beta-lactoglobulin (BLG) gene via zinc-finger nucleases in cattle. Cell Research, 21, 1638–1640.
-
(2011)
Cell Research
, vol.21
, pp. 1638-1640
-
-
Yu, S.1
Luo, J.2
Song, Z.3
Ding, F.4
Dai, Y.5
Li, N.6
-
93
-
-
84975678715
-
Cpf1 is a single RNA-guided endonuclease of a class 2 CRISPR-Cas system
-
Zetsche, B., Gootenberg, J. S., Abudayyeh, O. O., Slaymaker, I. M., Makarova, K. S., Essletzbichler, P., … Zhang, F. (2015). Cpf1 is a single RNA-guided endonuclease of a class 2 CRISPR-Cas system. Cell, 163, 759–771.
-
(2015)
Cell
, vol.163
, pp. 759-771
-
-
Zetsche, B.1
Gootenberg, J.S.2
Abudayyeh, O.O.3
Slaymaker, I.M.4
Makarova, K.S.5
Essletzbichler, P.6
Zhang, F.7
|