-
1
-
-
16944364045
-
A deletion in the bovine myostatin gene causes the double-muscled phenotype in cattle
-
Grobet, L. et al. A deletion in the bovine myostatin gene causes the double-muscled phenotype in cattle. Nat Genet 17, 71-74 (1997).
-
(1997)
Nat Genet
, vol.17
, pp. 71-74
-
-
Grobet, L.1
-
2
-
-
0030840359
-
Double muscling in cattle due to mutations in the myostatin gene
-
McPherron, A. C. & Lee, S. J. Double muscling in cattle due to mutations in the myostatin gene. Proc Natl Acad Sci USA 94, 12457-12461 (1997).
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 12457-12461
-
-
McPherron, A.C.1
Lee, S.J.2
-
3
-
-
0035979253
-
Regulation of myostatin activity and muscle growth
-
Lee, S. J. & McPherron, A. C. Regulation of myostatin activity and muscle growth. Proc Natl Acad Sci USA 98, 9306-9311 (2001).
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 9306-9311
-
-
Lee, S.J.1
McPherron, A.C.2
-
4
-
-
0037165983
-
Induction of cachexia in mice by systemically administered myostatin
-
Zimmers, T. A. et al. Induction of cachexia in mice by systemically administered myostatin. Science 296, 1486-1488 (2002).
-
(2002)
Science
, vol.296
, pp. 1486-1488
-
-
Zimmers, T.A.1
-
5
-
-
0037841469
-
Regulation of myostatin in vivo by growth and differentiation factorassociated serum protein-1: A novel protein with protease inhibitor and follistatin domains
-
Hill, J. J., Qiu, Y., Hewick, R. M. & Wolfman, N. M. Regulation of myostatin in vivo by growth and differentiation factorassociated serum protein-1: A novel protein with protease inhibitor and follistatin domains. Mol Endocrinol 17, 1144-1154 (2003).
-
(2003)
Mol Endocrinol
, vol.17
, pp. 1144-1154
-
-
Hill, J.J.1
Qiu, Y.2
Hewick, R.M.3
Wolfman, N.M.4
-
6
-
-
0031010050
-
Regulation of skeletal muscle mass in mice by a new TGF-beta superfamily member
-
McPherron, A. C., Lawler, A. M. & Lee, S. J. Regulation of skeletal muscle mass in mice by a new TGF-beta superfamily member. Nature 387, 83-90 (1997).
-
(1997)
Nature
, vol.387
, pp. 83-90
-
-
McPherron, A.C.1
Lawler, A.M.2
Lee, S.J.3
-
7
-
-
0036895736
-
Loss of myostatin attenuates severity of muscular dystrophy in mdx mice
-
Wagner, K. R., McPherron, A. C., Winik, N. & Lee, S. J. Loss of myostatin attenuates severity of muscular dystrophy in mdx mice. Ann Neurol 52, 832-836 (2002).
-
(2002)
Ann Neurol
, vol.52
, pp. 832-836
-
-
Wagner, K.R.1
McPherron, A.C.2
Winik, N.3
Lee, S.J.4
-
8
-
-
38349145459
-
Quadrupling muscle mass in mice by targeting TGF-beta signaling pathways
-
Lee, S. J. Quadrupling muscle mass in mice by targeting TGF-beta signaling pathways. PLoS One 2, e789 (2007).
-
(2007)
PLoS One
, vol.2
, pp. e789
-
-
Lee, S.J.1
-
9
-
-
0037191752
-
Functional improvement of dystrophic muscle by myostatin blockade
-
Bogdanovich, S. et al. Functional improvement of dystrophic muscle by myostatin blockade. Nature 420, 418-421 (2002).
-
(2002)
Nature
, vol.420
, pp. 418-421
-
-
Bogdanovich, S.1
-
10
-
-
67649668906
-
Molecular, cellular and physiological investigation of myostatin propeptide-mediated muscle growth in adult mice
-
Matsakas, A. et al. Molecular, cellular and physiological investigation of myostatin propeptide-mediated muscle growth in adult mice. Neuromuscul Disord 19, 489-499 (2009).
-
(2009)
Neuromuscul Disord
, vol.19
, pp. 489-499
-
-
Matsakas, A.1
-
11
-
-
0034792235
-
Expression of myostatin pro domain results in muscular transgenic mice
-
Yang, J. et al. Expression of myostatin pro domain results in muscular transgenic mice. Mol Reprod Dev 60, 351-361 (2001).
-
(2001)
Mol Reprod Dev
, vol.60
, pp. 351-361
-
-
Yang, J.1
-
12
-
-
0036200822
-
Suppression of body fat accumulation in myostatin-deficient mice
-
McPherron, A. C. & Lee, S. J. Suppression of body fat accumulation in myostatin-deficient mice. J Clin Invest 109, 595-601 (2002).
-
(2002)
J Clin Invest
, vol.109
, pp. 595-601
-
-
McPherron, A.C.1
Lee, S.J.2
-
13
-
-
0031989255
-
Association of the muscle hypertrophy locus with carcass traits in beef cattle
-
Casas, E. et al. Association of the muscle hypertrophy locus with carcass traits in beef cattle. J Anim Sci 76, 468-473 (1998).
-
(1998)
J Anim Sci
, vol.76
, pp. 468-473
-
-
Casas, E.1
-
14
-
-
0034371874
-
Effect of dietary energy and protein levels on fatty acid composition of intramuscular fat in double-muscled Belgian Blue bulls
-
Smet, S. D., Webb, E. C., Claeys, E., Uytterhaegen, L. & Demeyer, D. I. Effect of dietary energy and protein levels on fatty acid composition of intramuscular fat in double-muscled Belgian Blue bulls. Meat Sci 56, 73-79 (2000).
-
(2000)
Meat Sci
, vol.56
, pp. 73-79
-
-
Smet, S.D.1
Webb, E.C.2
Claeys, E.3
Uytterhaegen, L.4
Demeyer, D.I.5
-
15
-
-
13844282120
-
Myostatin and its implications on animal breeding: A review
-
Bellinge, R. H., Liberles, D. A., Iaschi, S. P., O'Brien, P. A. & Tay, G. K. Myostatin and its implications on animal breeding: A review. Anim Genet 36, 1-6 (2005).
-
(2005)
Anim Genet
, vol.36
, pp. 1-6
-
-
Bellinge, R.H.1
Liberles, D.A.2
Iaschi, S.P.3
O'Brien, P.A.4
Tay, G.K.5
-
16
-
-
1542350622
-
Domestic-Animal genomics: Deciphering the genetics of complex traits
-
Andersson, L. & Georges, M. Domestic-Animal genomics: deciphering the genetics of complex traits. Nat Rev Genet 5, 202-212 (2004).
-
(2004)
Nat Rev Genet
, vol.5
, pp. 202-212
-
-
Andersson, L.1
Georges, M.2
-
17
-
-
77952011904
-
Combination of myostatin pathway interference and dystrophin rescue enhances tetanic and specific force in dystrophic mdx mice
-
Dumonceaux, J. et al. Combination of myostatin pathway interference and dystrophin rescue enhances tetanic and specific force in dystrophic mdx mice. Mol Ther 18, 881-887 (2010).
-
(2010)
Mol Ther
, vol.18
, pp. 881-887
-
-
Dumonceaux, J.1
-
18
-
-
84887325477
-
Dual myostatin and dystrophin exon skipping by morpholino nucleic acid oligomers conjugated to a cellpenetrating peptide is a promising therapeutic strategy for the treatment of duchenne muscular dystrophy
-
Malerba, A. et al. Dual Myostatin and Dystrophin Exon Skipping by Morpholino Nucleic Acid Oligomers Conjugated to a Cellpenetrating Peptide Is a Promising Therapeutic Strategy for the Treatment of Duchenne Muscular Dystrophy. Mol Ther Nucleic Acids 1, e62 (2012).
-
(2012)
Mol Ther Nucleic Acids
, vol.1
, pp. e62
-
-
Malerba, A.1
-
19
-
-
84878063536
-
Local applications of myostatin-siRNA with atelocollagen increase skeletal muscle mass and recovery of muscle function
-
Kawakami, E. et al. Local applications of myostatin-siRNA with atelocollagen increase skeletal muscle mass and recovery of muscle function. PLoS One 8, e64719 (2013).
-
(2013)
PLoS One
, vol.8
, pp. e64719
-
-
Kawakami, E.1
-
20
-
-
45549109223
-
Myostatin, activin receptor IIb, and follistatin-like-3 gene expression are altered in adipose tissue and skeletal muscle of obese mice
-
Allen, D. L. et al. Myostatin, activin receptor IIb, and follistatin-like-3 gene expression are altered in adipose tissue and skeletal muscle of obese mice. Am J Physiol Endocrinol Metab 294, E918-927 (2008).
-
(2008)
Am J Physiol Endocrinol Metab
, vol.294
, pp. E918-927
-
-
Allen, D.L.1
-
21
-
-
84866603544
-
Myostatin inhibition prevents diabetes and hyperphagia in a mouse model of lipodystrophy
-
Guo, T. et al. Myostatin inhibition prevents diabetes and hyperphagia in a mouse model of lipodystrophy. Diabetes 61, 2414-2423 (2012).
-
(2012)
Diabetes
, vol.61
, pp. 2414-2423
-
-
Guo, T.1
-
22
-
-
80052969358
-
Expression and function of myostatin in obesity, diabetes, and exercise adaptation
-
Allen, D. L., Hittel, D. S. & McPherron, A. C. Expression and function of myostatin in obesity, diabetes, and exercise adaptation. Med Sci Sports Exerc 43, 1828-1835 (2011).
-
(2011)
Med Sci Sports Exerc
, vol.43
, pp. 1828-1835
-
-
Allen, D.L.1
Hittel, D.S.2
McPherron, A.C.3
-
23
-
-
25844484021
-
Transgenic expression of myostatin propeptide prevents diet-induced obesity and insulin resistance
-
Zhao, B., Wall, R. J. & Yang, J. Transgenic expression of myostatin propeptide prevents diet-induced obesity and insulin resistance. Biochem Biophys Res Commun 337, 248-255 (2005).
-
(2005)
Biochem Biophys Res Commun
, vol.337
, pp. 248-255
-
-
Zhao, B.1
Wall, R.J.2
Yang, J.3
-
24
-
-
40849086138
-
Enhanced muscle by myostatin propeptide increases adipose tissue adiponectin, PPAR-Alpha, and PPAR-gamma expressions
-
Suzuki, S. T., Zhao, B. & Yang, J. Enhanced muscle by myostatin propeptide increases adipose tissue adiponectin, PPAR-Alpha, and PPAR-gamma expressions. Biochem Biophys Res Commun 369, 767-773 (2008).
-
(2008)
Biochem Biophys Res Commun
, vol.369
, pp. 767-773
-
-
Suzuki, S.T.1
Zhao, B.2
Yang, J.3
-
25
-
-
33745577150
-
A mutation creating a potential illegitimate microRNA target site in the myostatin gene affects muscularity in sheep
-
Clop, A. et al. A mutation creating a potential illegitimate microRNA target site in the myostatin gene affects muscularity in sheep. Nat Genet 38, 813-818 (2006).
-
(2006)
Nat Genet
, vol.38
, pp. 813-818
-
-
Clop, A.1
-
26
-
-
34249733201
-
A mutation in the myostatin gene increases muscle mass and enhances racing performance in heterozygote dogs
-
Mosher, D. S. et al. A mutation in the myostatin gene increases muscle mass and enhances racing performance in heterozygote dogs. PLoS Genet 3, e79 (2007).
-
(2007)
PLoS Genet
, vol.3
, pp. e79
-
-
Mosher, D.S.1
-
27
-
-
2942735123
-
Myostatin mutation associated with gross muscle hypertrophy in a child
-
Schuelke, M. et al. Myostatin mutation associated with gross muscle hypertrophy in a child. N Engl J Med 350, 2682-2688 (2004).
-
(2004)
N Engl J Med
, vol.350
, pp. 2682-2688
-
-
Schuelke, M.1
-
28
-
-
0037235629
-
Transgenic swine for biomedicine and agriculture
-
Prather, R. S., Hawley, R. J., Carter, D. B., Lai, L. & Greenstein, J. L. Transgenic swine for biomedicine and agriculture. Theriogenology 59, 115-123 (2003).
-
(2003)
Theriogenology
, vol.59
, pp. 115-123
-
-
Prather, R.S.1
Hawley, R.J.2
Carter, D.B.3
Lai, L.4
Greenstein, J.L.5
-
29
-
-
80054732035
-
Genetic modifications of pigs for medicine and agriculture
-
Whyte, J. J. & Prather, R. S. Genetic modifications of pigs for medicine and agriculture. Mol Reprod Dev 78, 879-891 (2011).
-
(2011)
Mol Reprod Dev
, vol.78
, pp. 879-891
-
-
Whyte, J.J.1
Prather, R.S.2
-
30
-
-
0022328882
-
Selection of breeds, strains and individual pigs for prolificacy
-
Legault, C. Selection of breeds, strains and individual pigs for prolificacy. J Reprod Fertil Suppl 33, 151-166 (1985).
-
(1985)
J Reprod Fertil Suppl
, vol.33
, pp. 151-166
-
-
Legault, C.1
-
31
-
-
78651322138
-
Targeted integration in rat and mouse embryos with zinc-finger nucleases
-
Cui, X. et al. Targeted integration in rat and mouse embryos with zinc-finger nucleases. Nat Biotechnol 29, 64-67 (2011).
-
(2011)
Nat Biotechnol
, vol.29
, pp. 64-67
-
-
Cui, X.1
-
32
-
-
85027921901
-
Generation of PPARγ mono-Allelic knockout pigs via zinc-finger nucleases and nuclear transfer cloning
-
Yang, D. et al. Generation of PPARγ mono-Allelic knockout pigs via zinc-finger nucleases and nuclear transfer cloning. Cell Res 21, 979-982 (2011).
-
(2011)
Cell Res
, vol.21
, pp. 979-982
-
-
Yang, D.1
-
34
-
-
33646018017
-
Breeding for societally important traits in pigs
-
Kanis, E., De Greef, K. H., Hiemstra, A. & van Arendonk, J. A. Breeding for societally important traits in pigs. J Anim Sci 83, 948-957 (2005).
-
(2005)
J Anim Sci
, vol.83
, pp. 948-957
-
-
Kanis, E.1
De Greef, K.H.2
Hiemstra, A.3
Van Arendonk, J.A.4
-
35
-
-
0029264917
-
Growth and body composition of Meishan and Yorkshire barrows and gilts
-
White, B. R. et al. Growth and body composition of Meishan and Yorkshire barrows and gilts. J Anim Sci 73, 738-749 (1995).
-
(1995)
J Anim Sci
, vol.73
, pp. 738-749
-
-
White, B.R.1
-
36
-
-
84921608506
-
Improving livestock for agriculture-Technological progress from random transgenesis to precision genome editing heralds a new era
-
Laible, G., Wei, J. & Wagner, S. Improving livestock for agriculture-Technological progress from random transgenesis to precision genome editing heralds a new era. Biotechnol J 10, 109-120 (2015).
-
(2015)
Biotechnol J
, vol.10
, pp. 109-120
-
-
Laible, G.1
Wei, J.2
Wagner, S.3
-
37
-
-
0030818314
-
Mutations in myostatin (GDF8) in double-muscled Belgian Blue and Piedmontese cattle
-
Kambadur, R., Sharma, M., Smith, T. P. & Bass, J. J. Mutations in myostatin (GDF8) in double-muscled Belgian Blue and Piedmontese cattle. Genome Res 7, 910-916 (1997).
-
(1997)
Genome Res
, vol.7
, pp. 910-916
-
-
Kambadur, R.1
Sharma, M.2
Smith, T.P.3
Bass, J.J.4
-
38
-
-
8444243360
-
Regulation of muscle mass by myostatin
-
Lee, S. J. Regulation of muscle mass by myostatin. Annu Rev Cell Dev Biol 20, 61-86 (2004).
-
(2004)
Annu Rev Cell Dev Biol
, vol.20
, pp. 61-86
-
-
Lee, S.J.1
-
39
-
-
40349085764
-
Myostatin promotes the terminal differentiation of embryonic muscle progenitors
-
Manceau, M. et al. Myostatin promotes the terminal differentiation of embryonic muscle progenitors. Genes Dev 22, 668-681 (2008).
-
(2008)
Genes Dev
, vol.22
, pp. 668-681
-
-
Manceau, M.1
-
40
-
-
84884629522
-
Regulation of GDF-11 and myostatin activity by GASP-1 and GASP-2
-
Lee, Y. S. & Lee, S. J. Regulation of GDF-11 and myostatin activity by GASP-1 and GASP-2. Proc Natl Acad Sci USA 110, E3713-3722 (2013).
-
(2013)
Proc Natl Acad Sci USA
, vol.110
, pp. E3713-3722
-
-
Lee, Y.S.1
Lee, S.J.2
-
41
-
-
0020638032
-
Muscle development in large and small pig fetuses.
-
Wigmore, P. M. & Stickland, N. C. Muscle development in large and small pig fetuses. J Anat 137 (Pt 2), 235-245 (1983).
-
(1983)
J Anat
, vol.137
, pp. 235-245
-
-
Wigmore, P.M.1
Stickland, N.C.2
-
42
-
-
0034200902
-
Growth-And breed-related changes of muscle fiber characteristics in cattle
-
Wegner, J. et al. Growth-And breed-related changes of muscle fiber characteristics in cattle. J Anim Sci 78, 1485-1496 (2000).
-
(2000)
J Anim Sci
, vol.78
, pp. 1485-1496
-
-
Wegner, J.1
-
43
-
-
0015654488
-
Muscle growth in the fetal and neonatal pig
-
Swatland, H. J. Muscle growth in the fetal and neonatal pig. J Anim Sci 37, 536-545 (1973).
-
(1973)
J Anim Sci
, vol.37
, pp. 536-545
-
-
Swatland, H.J.1
-
44
-
-
78651362138
-
Identification of a second gene associated with variation in vertebral number in domestic pigs
-
Mikawa, S. et al. Identification of a second gene associated with variation in vertebral number in domestic pigs. BMC Genet 12, 5 (2011).
-
(2011)
BMC Genet
, vol.12
, Issue.5
-
-
Mikawa, S.1
-
45
-
-
84870330188
-
Strong signatures of selection in the domestic pig genome
-
Rubin, C. J. et al. Strong signatures of selection in the domestic pig genome. Proc Natl Acad Sci USA 109, 19529-19536 (2012).
-
(2012)
Proc Natl Acad Sci USA
, vol.109
, pp. 19529-19536
-
-
Rubin, C.J.1
-
46
-
-
10644247672
-
Carcass length in the bacon pig; Its association with vertebrae numbers and prediction from radiographs of the young pig
-
King, J. W. B. & Roberts, R. C. Carcass length in the bacon pig; its association with vertebrae numbers and prediction from radiographs of the young pig. Animal Production 2, 59-65 (1960).
-
(1960)
Animal Production
, vol.2
, pp. 59-65
-
-
King, J.W.B.1
Roberts, R.C.2
-
47
-
-
64249143104
-
Redundancy of myostatin and growth/differentiation factor 11 function
-
McPherron, A. C., Huynh, T. V. & Lee, S. J. Redundancy of myostatin and growth/differentiation factor 11 function. BMC Dev Biol 9, 24 (2009).
-
(2009)
BMC Dev Biol
, vol.9
, pp. 24
-
-
McPherron, A.C.1
Huynh, T.V.2
Lee, S.J.3
-
48
-
-
78649541528
-
Transgenic over-expression of growth differentiation factor 11 propeptide in skeleton results in transformation of the seventh cervical vertebra into a thoracic vertebra
-
Li, Z., Kawasumi, M., Zhao, B., Moisyadi, S. & Yang, J. Transgenic over-expression of growth differentiation factor 11 propeptide in skeleton results in transformation of the seventh cervical vertebra into a thoracic vertebra. Mol Reprod Dev 77, 990-997 (2010).
-
(2010)
Mol Reprod Dev
, vol.77
, pp. 990-997
-
-
Li, Z.1
Kawasumi, M.2
Zhao, B.3
Moisyadi, S.4
Yang, J.5
-
49
-
-
84855868347
-
Transgenic overexpression of bone morphogenetic protein 11 propeptide in skeleton enhances bone formation
-
Li, Z. et al. Transgenic overexpression of bone morphogenetic protein 11 propeptide in skeleton enhances bone formation. Biochem Biophys Res Commun 416, 289-292 (2011).
-
(2011)
Biochem Biophys Res Commun
, vol.416
, pp. 289-292
-
-
Li, Z.1
-
50
-
-
84899454477
-
Myostatin regulates tissue potency and cardiac calcium-handling proteins
-
Jackson, M. F., Li, N. & Rodgers, B. D. Myostatin regulates tissue potency and cardiac calcium-handling proteins. Endocrinology 155, 1771-1785 (2014).
-
(2014)
Endocrinology
, vol.155
, pp. 1771-1785
-
-
Jackson, M.F.1
Li, N.2
Rodgers, B.D.3
-
51
-
-
84891363681
-
A myostatin and activin decoy receptor enhances bone formation in mice
-
Bialek, P. et al. A myostatin and activin decoy receptor enhances bone formation in mice. Bone 60, 162-171 (2014).
-
(2014)
Bone
, vol.60
, pp. 162-171
-
-
Bialek, P.1
-
52
-
-
0021099059
-
Characterization of sarcomeric myosin heavy chain genes
-
Wydro, R. M., Nguyen, H. T., Gubits, R. M. & Nadal-Ginard, B. Characterization of sarcomeric myosin heavy chain genes. J Biol Chem 258, 670-678 (1983).
-
(1983)
J Biol Chem
, vol.258
, pp. 670-678
-
-
Wydro, R.M.1
Nguyen, H.T.2
Gubits, R.M.3
Nadal-Ginard, B.4
-
53
-
-
67749106611
-
Knockout rats via embryo microinjection of zinc-finger nucleases
-
Geurts, A. M. et al. Knockout rats via embryo microinjection of zinc-finger nucleases. Science 325, 433 (2009).
-
(2009)
Science
, vol.325
, pp. 433
-
-
Geurts, A.M.1
-
54
-
-
34848842733
-
Piglets born from handmade cloning, an innovative cloning method without micromanipulation
-
Du, Y. et al. Piglets born from handmade cloning, an innovative cloning method without micromanipulation. Theriogenology 68, 1104-1110 (2007).
-
(2007)
Theriogenology
, vol.68
, pp. 1104-1110
-
-
Du, Y.1
|