The CRISPR-associated DNA-cleaving enzyme Cpf1 also processes precursor CRISPR RNA

Nature

Volumn 532, Issue 7600, 2016, Pages 517-521

  Fonfara, Ines ^a,b,c   Richter, Hagen ^b,c   BratoviÄ, Majda ^b,c,d   Le Rhun, Anaïs ^a,b,c   Charpentier, Emmanuelle ^a,b,c,d  

^a UMEÅ UNIVERSITY   (Sweden)

^b HELMHOLTZ CENTRE FOR INFECTION RESEARCH   (Germany)

^c MAX PLANCK INSTITUTE FOR INFECTION BIOLOGY   (Germany)

^d HANNOVER MEDICAL SCHOOL   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CPF1 PROTEIN; CRISPR ASSOCIATED PROTEIN; DEOXYRIBONUCLEASE; PRECURSOR CRISPR RNA; RIBONUCLEASE; RNA PRECURSOR; UNCLASSIFIED DRUG; BACTERIAL PROTEIN; BACTERIAL RNA; CALCIUM; GUIDE RNA;

BACTERIUM; DNA; ENZYME; ENZYME ACTIVITY; GENE; GENE EXPRESSION; GENETIC ANALYSIS; MAGNESIUM; RNA;

ARTICLE; CONTROLLED STUDY; CRISPR CAS SYSTEM; DNA CLEAVAGE; DNA STRAND; DOUBLE STRANDED DNA BREAK; ENZYME ACTIVITY; ENZYME SUBSTRATE COMPLEX; IN VITRO STUDY; NONHUMAN; PRIORITY JOURNAL; PROTEIN RNA BINDING; RNA CLEAVAGE; BIOSYNTHESIS; CHEMISTRY; CLUSTERED REGULARLY INTERSPACED SHORT PALINDROMIC REPEAT; CONFORMATION; DRUG EFFECTS; ENZYME ACTIVE SITE; ENZYME SPECIFICITY; ENZYMOLOGY; FRANCISELLA; GENETICS; METABOLISM; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; RNA PROCESSING;

FRANCISELLA TULARENSIS SUBSP. NOVICIDA;

BACTERIAL PROTEINS; BASE SEQUENCE; CALCIUM; CATALYTIC DOMAIN; CLUSTERED REGULARLY INTERSPACED SHORT PALINDROMIC REPEATS; CRISPR-ASSOCIATED PROTEINS; CRISPR-CAS SYSTEMS; DNA CLEAVAGE; FRANCISELLA; MOLECULAR SEQUENCE DATA; NUCLEIC ACID CONFORMATION; RNA PRECURSORS; RNA PROCESSING, POST-TRANSCRIPTIONAL; RNA, BACTERIAL; RNA, GUIDE; SUBSTRATE SPECIFICITY;

EID: 84964862130     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature17945     Document Type: Article

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