메뉴 건너뛰기




Volumn 8, Issue 8, 2016, Pages

Bioactive compounds and their neuroprotective effects in diabetic complications

Author keywords

Diabetes; Flavonoids; Neuroprotection; Vitamins

Indexed keywords

ALPHA TOCOPHEROL; ASCORBIC ACID; BAICALEIN; CHRYSIN; DIOSMIN; EPIGALLOCATECHIN GALLATE; FLAVANONE; FLAVONOID; HESPERIDIN; ISOFLAVONOID; KAEMPFEROL; LUTEOLIN; MYRICETIN; NARINGENIN; PROANTHOCYANIDIN; PUERARIN; QUERCETIN; RETINOIC ACID; RUTOSIDE; SILIBININ; VITAMIN D; NEUROPROTECTIVE AGENT; VITAMIN;

EID: 85015586633     PISSN: None     EISSN: 20726643     Source Type: Journal    
DOI: 10.3390/nu8080472     Document Type: Review
Times cited : (46)

References (148)
  • 1
    • 0035928391 scopus 로고    scopus 로고
    • Type 1 diabetes: New perspectives on disease pathogenesis and treatment
    • CrossRef]
    • Atkinson, M.A.; Eisenbarth, G.S. Type 1 diabetes: New perspectives on disease pathogenesis and treatment. Lancet 2001, 358, 221-229. [CrossRef]
    • (2001) Lancet , vol.358 , pp. 221-229
    • Atkinson, M.A.1    Eisenbarth, G.S.2
  • 2
    • 73949146152 scopus 로고    scopus 로고
    • Current views on type 2 diabetes
    • CrossRef] [PubMed]
    • Lin, Y.; Sun, Z. Current views on type 2 diabetes. J. Endocrinol. 2010, 204, 1-11. [CrossRef] [PubMed]
    • (2010) J. Endocrinol , vol.204 , pp. 1-11
    • Lin, Y.1    Sun, Z.2
  • 3
    • 84937523993 scopus 로고    scopus 로고
    • 50 years forward: Mechanisms of hyperglycaemia-driven diabetic complications
    • CrossRef] [PubMed]
    • Russell, N.D.; Cooper, M.E. 50 years forward: Mechanisms of hyperglycaemia-driven diabetic complications. Diabetologia 2015, 58, 1708-1714. [CrossRef] [PubMed]
    • (2015) Diabetologia , vol.58 , pp. 1708-1714
    • Russell, N.D.1    Cooper, M.E.2
  • 4
    • 33846940322 scopus 로고    scopus 로고
    • Early diabetic neuropathy: Triggers and mechanisms
    • CrossRef] [PubMed]
    • Dobretsov, M.; Romanovsky, D.; Stimers, J.R. Early diabetic neuropathy: Triggers and mechanisms. World J. Gastroenterol. WJG 2007, 13, 175-191. [CrossRef] [PubMed]
    • (2007) World J. Gastroenterol. WJG , vol.13 , pp. 175-191
    • Dobretsov, M.1    Romanovsky, D.2    Stimers, J.R.3
  • 5
    • 84861111124 scopus 로고    scopus 로고
    • Diabetic neuropathy: Clinical manifestations and current treatments
    • CrossRef]
    • Callaghan, B.C.; Cheng, H.T.; Stables, C.L.; Smith, A.L.; Feldman, E.L. Diabetic neuropathy: Clinical manifestations and current treatments. Lancet. Neurol. 2012, 11, 521-534. [CrossRef]
    • (2012) Lancet. Neurol , vol.11 , pp. 521-534
    • Callaghan, B.C.1    Cheng, H.T.2    Stables, C.L.3    Smith, A.L.4    Feldman, E.L.5
  • 6
    • 84856201567 scopus 로고    scopus 로고
    • Advances in the epidemiology, pathogenesis and management of diabetic peripheral neuropathy
    • CrossRef] [PubMed]
    • Tesfaye, S.; Selvarajah, D. Advances in the epidemiology, pathogenesis and management of diabetic peripheral neuropathy. Diabetes/Metab. Res. Rev. 2012, 28, 8-14. [CrossRef] [PubMed]
    • (2012) Diabetes/Metab. Res. Rev , vol.28 , pp. 8-14
    • Tesfaye, S.1    Selvarajah, D.2
  • 7
    • 77955433933 scopus 로고    scopus 로고
    • Animal models and biomarkers of neuropathy in diabetic rodents
    • [PubMed]
    • Shaikh, A.S.; Somani, R.S. Animal models and biomarkers of neuropathy in diabetic rodents. Indian J. Pharmacol. 2010, 42, 129-134. [PubMed]
    • (2010) Indian J. Pharmacol , vol.42 , pp. 129-134
    • Shaikh, A.S.1    Somani, R.S.2
  • 8
    • 4444295693 scopus 로고    scopus 로고
    • Oxidative stress and antioxidant defense in relation to the severity of diabetic polyneuropathy and cardiovascular autonomic neuropathy
    • CrossRef] [PubMed]
    • Ziegler, D.; Sohr, C.G.; Nourooz-Zadeh, J. Oxidative stress and antioxidant defense in relation to the severity of diabetic polyneuropathy and cardiovascular autonomic neuropathy. Diabetes Care 2004, 27, 2178-2183. [CrossRef] [PubMed]
    • (2004) Diabetes Care , vol.27 , pp. 2178-2183
    • Ziegler, D.1    Sohr, C.G.2    Nourooz-Zadeh, J.3
  • 9
    • 0037184495 scopus 로고    scopus 로고
    • Molecular understanding of hyperglycemia1s adverse effects for diabetic complications
    • CrossRef]
    • Sheetz, M.J.; King, G.L. Molecular understanding of hyperglycemia1s adverse effects for diabetic complications. J. Am. Med. Assoc. 2002, 288, 2579-2588. [CrossRef]
    • (2002) J. Am. Med. Assoc , vol.288 , pp. 2579-2588
    • Sheetz, M.J.1    King, G.L.2
  • 10
    • 4143110556 scopus 로고    scopus 로고
    • Oxidative stress in the pathogenesis of diabetic neuropathy
    • CrossRef] [PubMed]
    • Vincent, A.M.; Russell, J.W.; Low, P.; Feldman, E.L. Oxidative stress in the pathogenesis of diabetic neuropathy. Endocr. Rev. 2004, 25, 612-628. [CrossRef] [PubMed]
    • (2004) Endocr. Rev , vol.25 , pp. 612-628
    • Vincent, A.M.1    Russell, J.W.2    Low, P.3    Feldman, E.L.4
  • 11
    • 0033635831 scopus 로고    scopus 로고
    • Rage: A multiligand receptor contributing to the cellular response in diabetic vasculopathy and inflammation
    • CrossRef] [PubMed]
    • Schmidt, A.M.; Hofmann, M.; Taguchi, A.; Yan, S.D.; Stern, D.M. Rage: A multiligand receptor contributing to the cellular response in diabetic vasculopathy and inflammation. Semin. Thromb. Hemost. 2000, 26, 485-493. [CrossRef] [PubMed]
    • (2000) Semin. Thromb. Hemost , vol.26 , pp. 485-493
    • Schmidt, A.M.1    Hofmann, M.2    Taguchi, A.3    Yan, S.D.4    Stern, D.M.5
  • 12
    • 0019965361 scopus 로고
    • The effect of aldose reductase inhibition on motor nerve conduction velocity in diabetic rats
    • CrossRef] [PubMed]
    • Yue, D.K.; Hanwell, M.A.; Satchell, P.M.; Turtle, J.R. The effect of aldose reductase inhibition on motor nerve conduction velocity in diabetic rats. Diabetes 1982, 31, 789-794. [CrossRef] [PubMed]
    • (1982) Diabetes , vol.31 , pp. 789-794
    • Yue, D.K.1    Hanwell, M.A.2    Satchell, P.M.3    Turtle, J.R.4
  • 13
    • 0022640893 scopus 로고
    • The effects of sorbinil on peripheral nerve conduction velocity, polyol concentrations and morphology in the streptozotocin-diabetic rat
    • CrossRef] [PubMed]
    • Cameron, N.E.; Leonard, M.B.; Ross, I.S.; Whiting, P.H. The effects of sorbinil on peripheral nerve conduction velocity, polyol concentrations and morphology in the streptozotocin-diabetic rat. Diabetologia 1986, 29, 168-174. [CrossRef] [PubMed]
    • (1986) Diabetologia , vol.29 , pp. 168-174
    • Cameron, N.E.1    Leonard, M.B.2    Ross, I.S.3    Whiting, P.H.4
  • 14
    • 0029085097 scopus 로고
    • Effects of an aldose reductase inhibitor, epalrestat, on diabetic neuropathy. Clinical benefit and indication for the drug assessed from the results of a placebo-controlled double-blind study
    • CrossRef]
    • Goto, Y.; Hotta, N.; Shigeta, Y.; Sakamoto, N.; Kikkawa, R. Effects of an aldose reductase inhibitor, epalrestat, on diabetic neuropathy. Clinical benefit and indication for the drug assessed from the results of a placebo-controlled double-blind study. Biome. Pharmacother. 1995, 49, 269-277. [CrossRef]
    • (1995) Biome. Pharmacother , vol.49 , pp. 269-277
    • Goto, Y.1    Hotta, N.2    Shigeta, Y.3    Sakamoto, N.4    Kikkawa, R.5
  • 15
    • 78651346887 scopus 로고    scopus 로고
    • Hyperglycemia magnifies schwann cell dysfunction and cell death triggered by PA-induced lipotoxicity
    • CrossRef] [PubMed]
    • Padilla, A.; Descorbeth, M.; Almeyda, A.L.; Payne, K.; de Leon, M. Hyperglycemia magnifies schwann cell dysfunction and cell death triggered by PA-induced lipotoxicity. Brain Res. 2011, 1370, 64-79. [CrossRef] [PubMed]
    • (2011) Brain Res , vol.1370 , pp. 64-79
    • Padilla, A.1    Descorbeth, M.2    Almeyda, A.L.3    Payne, K.4    De Leon, M.5
  • 17
    • 33846460101 scopus 로고    scopus 로고
    • Receptor for advanced glycation end products activation injures primary sensory neurons via oxidative stress
    • CrossRef] [PubMed]
    • Vincent, A.M.; Perrone, L.; Sullivan, K.A.; Backus, C.; Sastry, A.M.; Lastoskie, C.; Feldman, E.L. Receptor for advanced glycation end products activation injures primary sensory neurons via oxidative stress. Endocrinology 2007, 148, 548-558. [CrossRef] [PubMed]
    • (2007) Endocrinology , vol.148 , pp. 548-558
    • Vincent, A.M.1    Perrone, L.2    Sullivan, K.A.3    Backus, C.4    Sastry, A.M.5    Lastoskie, C.6    Feldman, E.L.7
  • 18
    • 0028918868 scopus 로고
    • Cholesterol-lowering therapy may retard the progression of diabetic nephropathy
    • CrossRef] [PubMed]
    • Lam, K.S.; Cheng, I.K.; Janus, E.D.; Pang, R.W. Cholesterol-lowering therapy may retard the progression of diabetic nephropathy. Diabetologia 1995, 38, 604-609. [CrossRef] [PubMed]
    • (1995) Diabetologia , vol.38 , pp. 604-609
    • Lam, K.S.1    Cheng, I.K.2    Janus, E.D.3    Pang, R.W.4
  • 19
    • 9444232789 scopus 로고    scopus 로고
    • Lipid lowering drugs prescription and the risk of peripheral neuropathy: An exploratory case-control study using automated databases
    • CrossRef] [PubMed]
    • Corrao, G.; Zambon, A.; Bertu, L.; Botteri, E.; Leoni, O.; Contiero, P. Lipid lowering drugs prescription and the risk of peripheral neuropathy: An exploratory case-control study using automated databases. J. Epidemiol. Community Health 2004, 58, 1047-1051. [CrossRef] [PubMed]
    • (2004) J. Epidemiol. Community Health , vol.58 , pp. 1047-1051
    • Corrao, G.1    Zambon, A.2    Bertu, L.3    Botteri, E.4    Leoni, O.5    Contiero, P.6
  • 20
    • 33645861113 scopus 로고    scopus 로고
    • Rescue and regeneration of injured peripheral nerve axons by intrathecal insulin
    • CrossRef] [PubMed]
    • Toth, C.; Brussee, V.; Martinez, J.A.; McDonald, D.; Cunningham, F.A.; Zochodne, D.W. Rescue and regeneration of injured peripheral nerve axons by intrathecal insulin. Neuroscience 2006, 139, 429-449. [CrossRef] [PubMed]
    • (2006) Neuroscience , vol.139 , pp. 429-449
    • Toth, C.1    Brussee, V.2    Martinez, J.A.3    McDonald, D.4    Cunningham, F.A.5    Zochodne, D.W.6
  • 21
    • 1842791603 scopus 로고    scopus 로고
    • Type 1 diabetic neuropathy and c-peptide
    • CrossRef] [PubMed]
    • Sima, A.A.; Zhang, W.; Grunberger, G. Type 1 diabetic neuropathy and c-peptide. Exp. Diabesity Res. 2004, 5, 65-77. [CrossRef] [PubMed]
    • (2004) Exp. Diabesity Res , vol.5 , pp. 65-77
    • Sima, A.A.1    Zhang, W.2    Grunberger, G.3
  • 22
    • 0347659441 scopus 로고    scopus 로고
    • Nerve growth factor and diabetic neuropathy
    • CrossRef] [PubMed]
    • Pittenger, G.; Vinik, A. Nerve growth factor and diabetic neuropathy. Exp. Diabesity Res 2003, 4, 271-285. [CrossRef] [PubMed]
    • (2003) Exp. Diabesity Res , vol.4 , pp. 271-285
    • Pittenger, G.1    Vinik, A.2
  • 24
    • 0036849077 scopus 로고    scopus 로고
    • The biochemistry and medical significance of the flavonoids. Pharmacol
    • CrossRef]
    • Havsteen, B.H. The biochemistry and medical significance of the flavonoids. Pharmacol. Ther. 2002, 96, 67-202. [CrossRef]
    • (2002) Ther , vol.96 , pp. 67-202
    • Havsteen, B.H.1
  • 25
    • 84969670586 scopus 로고    scopus 로고
    • The possible role of flavonoids in the prevention of diabetic complications
    • CrossRef] [PubMed]
    • Testa, R.; Bonfigli, A.R.; Genovese, S.; de Nigris, V.; Ceriello, A. The possible role of flavonoids in the prevention of diabetic complications. Nutrients 2016, 8, 310. [CrossRef] [PubMed]
    • (2016) Nutrients , vol.8 , pp. 310
    • Testa, R.1    Bonfigli, A.R.2    Genovese, S.3    De Nigris, V.4    Ceriello, A.5
  • 26
    • 0035919828 scopus 로고    scopus 로고
    • Baicalein protects cortical neurons from beta-amyloid (25-35) induced toxicity
    • CrossRef] [PubMed]
    • Lebeau, A.; Esclaire, F.; Rostene, W.; Pelaprat, D. Baicalein protects cortical neurons from beta-amyloid (25-35) induced toxicity. Neuroreport 2001, 12, 2199-2202. [CrossRef] [PubMed]
    • (2001) Neuroreport , vol.12 , pp. 2199-2202
    • Lebeau, A.1    Esclaire, F.2    Rostene, W.3    Pelaprat, D.4
  • 27
    • 0034950875 scopus 로고    scopus 로고
    • Protective effects of flavonoids in the roots of scutellaria baicalensis georgi against hydrogen peroxide-induced oxidative stress in Hs-SY5Y cells. Pharmacol
    • CrossRef] [PubMed]
    • Gao, Z.; Huang, K.; Xu, H. Protective effects of flavonoids in the roots of scutellaria baicalensis georgi against hydrogen peroxide-induced oxidative stress in Hs-SY5Y cells. Pharmacol. Res. 2001, 43, 173-178. [CrossRef] [PubMed]
    • (2001) Res , vol.43 , pp. 173-178
    • Gao, Z.1    Huang, K.2    Xu, H.3
  • 28
    • 20044389086 scopus 로고    scopus 로고
    • Inhibition of microglial activation by the herbal flavonoid baicalein attenuates inflammation-mediated degeneration of dopaminergic neurons
    • CrossRef] [PubMed]
    • Li, F.Q.; Wang, T.; Pei, Z.; Liu, B.; Hong, J.S. Inhibition of microglial activation by the herbal flavonoid baicalein attenuates inflammation-mediated degeneration of dopaminergic neurons. J. Neural Transm. 2005, 112, 331-347. [CrossRef] [PubMed]
    • (2005) J. Neural Transm , vol.112 , pp. 331-347
    • Li, F.Q.1    Wang, T.2    Pei, Z.3    Liu, B.4    Hong, J.S.5
  • 29
    • 79958027982 scopus 로고    scopus 로고
    • Baicalein alleviates diabetic peripheral neuropathy through inhibition of oxidative-nitrosative stress and p38 MAPK activation
    • CrossRef] [PubMed]
    • Stavniichuk, R.; Drel, V.R.; Shevalye, H.; Maksimchyk, Y.; Kuchmerovska, T.M.; Nadler, J.L.; Obrosova, I.G. Baicalein alleviates diabetic peripheral neuropathy through inhibition of oxidative-nitrosative stress and p38 MAPK activation. Exp. Neurol. 2011, 230, 106-113. [CrossRef] [PubMed]
    • (2011) Exp. Neurol , vol.230 , pp. 106-113
    • Stavniichuk, R.1    Drel, V.R.2    Shevalye, H.3    Maksimchyk, Y.4    Kuchmerovska, T.M.5    Nadler, J.L.6    Obrosova, I.G.7
  • 30
    • 54349118995 scopus 로고    scopus 로고
    • Protective effects of Chinese propolis and its component, chrysin, against neuronal cell death via inhibition of mitochondrial apoptosis pathway in SH-SY5Y cells
    • CrossRef] [PubMed]
    • Izuta, H.; Shimazawa, M.; Tazawa, S.; Araki, Y.; Mishima, S.; Hara, H. Protective effects of Chinese propolis and its component, chrysin, against neuronal cell death via inhibition of mitochondrial apoptosis pathway in SH-SY5Y cells. J. Agric. Food Chem. 2008, 56, 8944-8953. [CrossRef] [PubMed]
    • (2008) J. Agric. Food Chem. , vol.56 , pp. 8944-8953
    • Izuta, H.1    Shimazawa, M.2    Tazawa, S.3    Araki, Y.4    Mishima, S.5    Hara, H.6
  • 31
    • 0037021579 scopus 로고    scopus 로고
    • Antioxidant and prooxidant effects of phenolics on pancreatic beta-cells in vitro
    • CrossRef] [PubMed]
    • Lapidot, T.; Walker, M.D.; Kanner, J. Antioxidant and prooxidant effects of phenolics on pancreatic beta-cells in vitro. J. Agric. Food Chem. 2002, 50, 7220-7225. [CrossRef] [PubMed]
    • (2002) J. Agric. Food Chem , vol.50 , pp. 7220-7225
    • Lapidot, T.1    Walker, M.D.2    Kanner, J.3
  • 32
    • 77957859355 scopus 로고    scopus 로고
    • Chrysin suppresses LPS-stimulated proinflammatory responses by blocking NF-kappaB and JNK activations in microglia cells
    • CrossRef] [PubMed]
    • Ha, S.K.; Moon, E.; Kim, S.Y. Chrysin suppresses LPS-stimulated proinflammatory responses by blocking NF-kappaB and JNK activations in microglia cells. Neurosci. Lett. 2010, 485, 143-147. [CrossRef] [PubMed]
    • (2010) Neurosci. Lett , vol.485 , pp. 143-147
    • Ha, S.K.1    Moon, E.2    Kim, S.Y.3
  • 33
    • 78651284870 scopus 로고    scopus 로고
    • Inhibition of CCAAT/enhancer binding protein delta expression by chrysin in microglial cells results in anti-inflammatory and neuroprotective effects
    • CrossRef] [PubMed]
    • Gresa-Arribas, N.; Serratosa, J.; Saura, J.; Sola, C. Inhibition of CCAAT/enhancer binding protein delta expression by chrysin in microglial cells results in anti-inflammatory and neuroprotective effects. J. Neurochem. 2010, 115, 526-536. [CrossRef] [PubMed]
    • (2010) J. Neurochem , vol.115 , pp. 526-536
    • Gresa-Arribas, N.1    Serratosa, J.2    Saura, J.3    Sola, C.4
  • 34
    • 84907592869 scopus 로고    scopus 로고
    • Chrysin ameliorates diabetes-associated cognitive deficits in wistar rats
    • CrossRef] [PubMed]
    • Li, R.; Zang, A.; Zhang, L.; Zhang, H.; Zhao, L.; Qi, Z.; Wang, H. Chrysin ameliorates diabetes-associated cognitive deficits in wistar rats. Neurol. Sci. 2014, 35, 1527-1532. [CrossRef] [PubMed]
    • (2014) Neurol. Sci. , vol.35 , pp. 1527-1532
    • Li, R.1    Zang, A.2    Zhang, L.3    Zhang, H.4    Zhao, L.5    Qi, Z.6    Wang, H.7
  • 35
    • 79957939863 scopus 로고    scopus 로고
    • Protective effect of diosmin on LPS-induced apoptosis in PC12 cells and inhibition of TNF-alpha expression
    • CrossRef] [PubMed]
    • Dholakiya, S.L.; Benzeroual, K.E. Protective effect of diosmin on LPS-induced apoptosis in PC12 cells and inhibition of TNF-alpha expression. Toxicol. Vitro 2011, 25, 1039-1044. [CrossRef] [PubMed]
    • (2011) Toxicol. Vitro , vol.25 , pp. 1039-1044
    • Dholakiya, S.L.1    Benzeroual, K.E.2
  • 36
    • 84897941780 scopus 로고    scopus 로고
    • Protective effect of diosmin against diabetic neuropathy in experimental rats
    • CrossRef]
    • Jain, D.; Bansal, M.K.; Dalvi, R.; Upganlawar, A.; Somani, R. Protective effect of diosmin against diabetic neuropathy in experimental rats. J. Integr. Med. 2014, 12, 35-41. [CrossRef]
    • (2014) J. Integr. Med , vol.12 , pp. 35-41
    • Jain, D.1    Bansal, M.K.2    Dalvi, R.3    Upganlawar, A.4    Somani, R.5
  • 37
    • 82055194290 scopus 로고    scopus 로고
    • Ameliorative effect of diosmin, a citrus flavonoid against streptozotocin-nicotinamide generated oxidative stress induced diabetic rats
    • CrossRef] [PubMed]
    • Srinivasan, S.; Pari, L. Ameliorative effect of diosmin, a citrus flavonoid against streptozotocin-nicotinamide generated oxidative stress induced diabetic rats. Chem. Biol. Interact. 2012, 195, 43-51. [CrossRef] [PubMed]
    • (2012) Chem. Biol. Interact , vol.195 , pp. 43-51
    • Srinivasan, S.1    Pari, L.2
  • 38
    • 0035930961 scopus 로고    scopus 로고
    • The green tea polyphenol (-)-epigallocatechin gallate attenuates beta-amyloid-induced neurotoxicity in cultured hippocampal neurons
    • CrossRef]
    • Choi, Y.T.; Jung, C.H.; Lee, S.R.; Bae, J.H.; Baek, W.K.; Suh, M.H.; Park, J.; Park, C.W.; Suh, S.I. The green tea polyphenol (-)-epigallocatechin gallate attenuates beta-amyloid-induced neurotoxicity in cultured hippocampal neurons. Life Sci. 2001, 70, 603-614. [CrossRef]
    • (2001) Life Sci , vol.70 , pp. 603-614
    • Choi, Y.T.1    Jung, C.H.2    Lee, S.R.3    Bae, J.H.4    Baek, W.K.5    Suh, M.H.6    Park, J.7    Park, C.W.8    Suh, S.I.9
  • 39
    • 84871355903 scopus 로고    scopus 로고
    • Chronic oral epigallocatechin-gallate alleviates streptozotocin-induced diabetic neuropathic hyperalgesia in rat: Involvement of oxidative stress. Iranian
    • Baluchnejadmojarad, T.; Roghani, M. Chronic oral epigallocatechin-gallate alleviates streptozotocin-induced diabetic neuropathic hyperalgesia in rat: Involvement of oxidative stress. Iranian J. Pharm. Res. 2012, 11, 1243-1253.
    • (2012) J. Pharm. Res , vol.11 , pp. 1243-1253
    • Baluchnejadmojarad, T.1    Roghani, M.2
  • 40
    • 84919935295 scopus 로고    scopus 로고
    • Nociceptive spinal cord neurons of laminae I-III exhibit oxidative stress damage during diabetic neuropathy which is prevented by early antioxidant treatment with epigallocatechin-gallate (EGCG). Brain Res
    • CrossRef] [PubMed]
    • Raposo, D.; Morgado, C.; Pereira-Terra, P.; Tavares, I. Nociceptive spinal cord neurons of laminae I-III exhibit oxidative stress damage during diabetic neuropathy which is prevented by early antioxidant treatment with epigallocatechin-gallate (EGCG). Brain Res. Bull. 2015, 110, 68-75. [CrossRef] [PubMed]
    • (2015) Bull , vol.110 , pp. 68-75
    • Raposo, D.1    Morgado, C.2    Pereira-Terra, P.3    Tavares, I.4
  • 41
    • 84876187514 scopus 로고    scopus 로고
    • Protective effects of hesperidin against amyloid-beta (Abeta) induced neurotoxicity through the voltage dependent anion channel 1 (VDAC1)-mediated mitochondrial apoptotic pathway in PC12 cells
    • CrossRef] [PubMed]
    • Wang, D.M.; Li, S.Q.; Zhu, X.Y.; Wang, Y.; Wu, W.L.; Zhang, X.J. Protective effects of hesperidin against amyloid-beta (Abeta) induced neurotoxicity through the voltage dependent anion channel 1 (VDAC1)-mediated mitochondrial apoptotic pathway in PC12 cells. Neurochem. Res. 2013, 38, 1034-1044. [CrossRef] [PubMed]
    • (2013) Neurochem. Res , vol.38 , pp. 1034-1044
    • Wang, D.M.1    Li, S.Q.2    Zhu, X.Y.3    Wang, Y.4    Wu, W.L.5    Zhang, X.J.6
  • 42
    • 80555126828 scopus 로고    scopus 로고
    • Hesperidin, a flavone glycoside, as mediator of neuronal survival
    • CrossRef] [PubMed]
    • Nones, J.; TC, E.S.; Gomes, F.C. Hesperidin, a flavone glycoside, as mediator of neuronal survival. Neurochem. Res. 2011, 36, 1776-1784. [CrossRef] [PubMed]
    • (2011) Neurochem. Res , vol.36 , pp. 1776-1784
    • Nones, J.1    Tc, E.S.2    Gomes, F.C.3
  • 43
    • 84899673615 scopus 로고    scopus 로고
    • Hesperidin, a flavanoglycone attenuates experimental diabetic neuropathy via modulation of cellular and biochemical marker to improve nerve functions
    • CrossRef] [PubMed]
    • Visnagri, A.; Kandhare, A.D.; Chakravarty, S.; Ghosh, P.; Bodhankar, S.L. Hesperidin, a flavanoglycone attenuates experimental diabetic neuropathy via modulation of cellular and biochemical marker to improve nerve functions. Pharm. Biol. 2014, 52, 814-828. [CrossRef] [PubMed]
    • (2014) Pharm. Biol , vol.52 , pp. 814-828
    • Visnagri, A.1    Kandhare, A.D.2    Chakravarty, S.3    Ghosh, P.4    Bodhankar, S.L.5
  • 44
    • 84920987667 scopus 로고    scopus 로고
    • Effect of hesperidin on neurobehavioral, neuroinflammation, oxidative stress and lipid alteration in intracerebroventricular streptozotocin induced cognitive impairment in mice
    • CrossRef] [PubMed]
    • Javed, H.; Vaibhav, K.; Ahmed, M.E.; Khan, A.; Tabassum, R.; Islam, F.; Safhi, M.M. Effect of hesperidin on neurobehavioral, neuroinflammation, oxidative stress and lipid alteration in intracerebroventricular streptozotocin induced cognitive impairment in mice. J. Neurol. Sci. 2015, 348, 51-59. [CrossRef] [PubMed]
    • (2015) J. Neurol. Sci. , vol.348 , pp. 51-59
    • Javed, H.1    Vaibhav, K.2    Ahmed, M.E.3    Khan, A.4    Tabassum, R.5    Islam, F.6    Safhi, M.M.7
  • 46
    • 0035895957 scopus 로고    scopus 로고
    • The neuroprotective effects of phytoestrogens on amyloid beta protein-induced toxicity are mediated by abrogating the activation of caspase cascade in rat cortical neurons
    • CrossRef] [PubMed]
    • Wang, C.N.; Chi, C.W.; Lin, Y.L.; Chen, C.F.; Shiao, Y.J. The neuroprotective effects of phytoestrogens on amyloid beta protein-induced toxicity are mediated by abrogating the activation of caspase cascade in rat cortical neurons. J. Biol. Chem. 2001, 276, 5287-5295. [CrossRef] [PubMed]
    • (2001) J. Biol. Chem , vol.276 , pp. 5287-5295
    • Wang, C.N.1    Chi, C.W.2    Lin, Y.L.3    Chen, C.F.4    Shiao, Y.J.5
  • 47
    • 84940051411 scopus 로고    scopus 로고
    • Ameliorative effect of kaempferol, a flavonoid, on oxidative stress in streptozotocin-induced diabetic rats
    • CrossRef] [PubMed]
    • Al-Numair, K.S.; Chandramohan, G.; Veeramani, C.; Alsaif, M.A. Ameliorative effect of kaempferol, a flavonoid, on oxidative stress in streptozotocin-induced diabetic rats. Redox Rep. Commun. Free Radic. Res. 2015, 20, 198-209. [CrossRef] [PubMed]
    • (2015) Redox Rep. Commun. Free Radic. Res , vol.20 , pp. 198-209
    • Al-Numair, K.S.1    Chandramohan, G.2    Veeramani, C.3    Alsaif, M.A.4
  • 48
    • 75749127381 scopus 로고    scopus 로고
    • Neuroprotective effect of luteolin on amyloid beta protein(25-35)-induced toxicity in cultured rat cortical neurons
    • CrossRef] [PubMed]
    • Cheng, H.Y.; Hsieh, M.T.; Tsai, F.S.; Wu, C.R.; Chiu, C.S.; Lee, M.M.; Xu, H.X.; Zhao, Z.Z.; Peng, W.H. Neuroprotective effect of luteolin on amyloid beta protein(25-35)-induced toxicity in cultured rat cortical neurons. Phytother. Res. 2010, 24 (Suppl. 1), S102-S108. [CrossRef] [PubMed]
    • (2010) Phytother. Res , vol.24 , pp. S102-S108
    • Cheng, H.Y.1    Hsieh, M.T.2    Tsai, F.S.3    Wu, C.R.4    Chiu, C.S.5    Lee, M.M.6    Xu, H.X.7    Zhao, Z.Z.8    Peng, W.H.9
  • 49
    • 77950632985 scopus 로고    scopus 로고
    • Neurotrophic and cytoprotective action of luteolin in PC12 cells through ERK-dependent induction of NRF2-driven Ho-1 expression
    • CrossRef] [PubMed]
    • Lin, C.W.; Wu, M.J.; Liu, I.Y.; Su, J.D.; Yen, J.H. Neurotrophic and cytoprotective action of luteolin in PC12 cells through ERK-dependent induction of NRF2-driven Ho-1 expression. J. Agric. Food Chem. 2010, 58, 4477-4486. [CrossRef] [PubMed]
    • (2010) J. Agric. Food Chem , vol.58 , pp. 4477-4486
    • Lin, C.W.1    Wu, M.J.2    Liu, I.Y.3    Su, J.D.4    Yen, J.H.5
  • 50
    • 84874740577 scopus 로고    scopus 로고
    • Luteolin attenuates diabetes-associated cognitive decline in rats
    • CrossRef] [PubMed]
    • Liu, Y.; Tian, X.; Gou, L.; Sun, L.; Ling, X.; Yin, X. Luteolin attenuates diabetes-associated cognitive decline in rats. Brain Res. Bull. 2013, 94, 23-29. [CrossRef] [PubMed]
    • (2013) Brain Res. Bull , vol.94 , pp. 23-29
    • Liu, Y.1    Tian, X.2    Gou, L.3    Sun, L.4    Ling, X.5    Yin, X.6
  • 51
    • 85013115056 scopus 로고    scopus 로고
    • Luteolin improves the impaired nerve functions in diabetic neuropathy: Behavioral and biochemical evidences
    • Li, M.; Li, Q.; Zhao, Q.; Zhang, J.; Lin, J. Luteolin improves the impaired nerve functions in diabetic neuropathy: Behavioral and biochemical evidences. Int. J. Exp. Pathol. 2015, 8, 10112-10120.
    • (2015) Int. J. Exp. Pathol , vol.8 , pp. 10112-10120
    • Li, M.1    Li, Q.2    Zhao, Q.3    Zhang, J.4    Lin, J.5
  • 52
    • 45549099959 scopus 로고    scopus 로고
    • Three distinct neuroprotective functions of myricetin against glutamate-induced neuronal cell death: Involvement of direct inhibition of caspase-3
    • CrossRef] [PubMed]
    • Shimmyo, Y.; Kihara, T.; Akaike, A.; Niidome, T.; Sugimoto, H. Three distinct neuroprotective functions of myricetin against glutamate-induced neuronal cell death: Involvement of direct inhibition of caspase-3. J. Neurosci. Res. 2008, 86, 1836-1845. [CrossRef] [PubMed]
    • (2008) J. Neurosci. Res , vol.86 , pp. 1836-1845
    • Shimmyo, Y.1    Kihara, T.2    Akaike, A.3    Niidome, T.4    Sugimoto, H.5
  • 53
    • 62349089860 scopus 로고    scopus 로고
    • The citrus flavanone naringenin inhibits inflammatory signalling in glial cells and protects against neuroinflammatory injury
    • CrossRef] [PubMed]
    • Vafeiadou, K.; Vauzour, D.; Lee, H.Y.; Rodriguez-Mateos, A.; Williams, R.J.; Spencer, J.P. The citrus flavanone naringenin inhibits inflammatory signalling in glial cells and protects against neuroinflammatory injury. Arch. Biochem. Biophys. 2009, 484, 100-109. [CrossRef] [PubMed]
    • (2009) Arch. Biochem. Biophys , vol.484 , pp. 100-109
    • Vafeiadou, K.1    Vauzour, D.2    Lee, H.Y.3    Rodriguez-Mateos, A.4    Williams, R.J.5    Spencer, J.P.6
  • 54
    • 84958225286 scopus 로고    scopus 로고
    • Naringenin suppresses neuroinflammatory responses through inducing suppressor of cytokine signaling 3 expression
    • CrossRef] [PubMed]
    • Wu, L.H.; Lin, C.; Lin, H.Y.; Liu, Y.S.; Wu, C.Y.; Tsai, C.F.; Chang, P.C.; Yeh, W.L.; Lu, D.Y. Naringenin suppresses neuroinflammatory responses through inducing suppressor of cytokine signaling 3 expression. Mol. Neurobiol. 2016, 53, 1080-1091. [CrossRef] [PubMed]
    • (2016) Mol. Neurobiol , vol.53 , pp. 1080-1091
    • Wu, L.H.1    Lin, C.2    Lin, H.Y.3    Liu, Y.S.4    Wu, C.Y.5    Tsai, C.F.6    Chang, P.C.7    Yeh, W.L.8    Lu, D.Y.9
  • 55
    • 84912014331 scopus 로고    scopus 로고
    • Role of naringenin in protection against diabetic hyperalgesia and tactile allodynia in male wistar rats
    • CrossRef] [PubMed]
    • Hasanein, P.; Fazeli, F. Role of naringenin in protection against diabetic hyperalgesia and tactile allodynia in male wistar rats. J. Physiol. Biochem. 2014, 70, 997-1006. [CrossRef] [PubMed]
    • (2014) J. Physiol. Biochem. , vol.70 , pp. 997-1006
    • Hasanein, P.1    Fazeli, F.2
  • 56
    • 84940180255 scopus 로고    scopus 로고
    • Naringenin neutralises oxidative stress and nerve growth factor discrepancy in experimental diabetic neuropathy
    • CrossRef] [PubMed]
    • Al-Rejaie, S.S.; Aleisa, A.M.; Abuohashish, H.M.; Parmar, M.Y.; Ola, M.S.; Al-Hosaini, A.A.; Ahmed, M.M. Naringenin neutralises oxidative stress and nerve growth factor discrepancy in experimental diabetic neuropathy. Neurol. Res. 2015, 37, 924-933. [CrossRef] [PubMed]
    • (2015) Neurol. Res , vol.37 , pp. 924-933
    • Al-Rejaie, S.S.1    Aleisa, A.M.2    Abuohashish, H.M.3    Parmar, M.Y.4    Ola, M.S.5    Al-Hosaini, A.A.6    Ahmed, M.M.7
  • 57
    • 0035707263 scopus 로고    scopus 로고
    • Protection of primary glial cells by grape seed proanthocyanidin extract against nitrosative/oxidative stress
    • CrossRef] [PubMed]
    • Roychowdhury, S.; Wolf, G.; Keilhoff, G.; Bagchi, D.; Horn, T. Protection of primary glial cells by grape seed proanthocyanidin extract against nitrosative/oxidative stress. Nitric Oxide 2001, 5, 137-149. [CrossRef] [PubMed]
    • (2001) Nitric Oxide , vol.5 , pp. 137-149
    • Roychowdhury, S.1    Wolf, G.2    Keilhoff, G.3    Bagchi, D.4    Horn, T.5
  • 58
    • 0345215163 scopus 로고    scopus 로고
    • Protective effects of grape seed proanthocyanidins and selected antioxidants against TPA-induced hepatic and brain lipid peroxidation and DNA fragmentation, and peritoneal macrophage activation in mice
    • CrossRef]
    • Bagchi, D.; Garg, A.; Krohn, R.L.; Bagchi, M.; Bagchi, D.J.; Balmoori, J.; Stohs, S.J. Protective effects of grape seed proanthocyanidins and selected antioxidants against TPA-induced hepatic and brain lipid peroxidation and DNA fragmentation, and peritoneal macrophage activation in mice. Gen. Pharmacol. 1998, 30, 771-776. [CrossRef]
    • (1998) Gen. Pharmacol , vol.30 , pp. 771-776
    • Bagchi, D.1    Garg, A.2    Krohn, R.L.3    Bagchi, M.4    Bagchi, D.J.5    Balmoori, J.6    Stohs, S.J.7
  • 59
    • 59049102102 scopus 로고    scopus 로고
    • Effects of grape seed proanthocyanidin extracts on peripheral nerves in streptozocin-induced diabetic rats
    • CrossRef] [PubMed]
    • Cui, X.P.; Li, B.Y.; Gao, H.Q.; Wei, N.; Wang, W.L.; Lu, M. Effects of grape seed proanthocyanidin extracts on peripheral nerves in streptozocin-induced diabetic rats. J. Nutr. Sci. Vitaminol. 2008, 54, 321-328. [CrossRef] [PubMed]
    • (2008) J. Nutr. Sci. Vitaminol , vol.54 , pp. 321-328
    • Cui, X.P.1    Li, B.Y.2    Gao, H.Q.3    Wei, N.4    Wang, W.L.5    Lu, M.6
  • 60
    • 84901832979 scopus 로고    scopus 로고
    • Proanthocyanidins protect against early diabetic peripheral neuropathy by modulating endoplasmic reticulum stress
    • CrossRef] [PubMed]
    • Ding, Y.; Dai, X.; Zhang, Z.; Jiang, Y.; Ma, X.; Cai, X.; Li, Y. Proanthocyanidins protect against early diabetic peripheral neuropathy by modulating endoplasmic reticulum stress. J. Nutr. Biochem. 2014, 25, 765-772. [CrossRef] [PubMed]
    • (2014) J. Nutr. Biochem , vol.25 , pp. 765-772
    • Ding, Y.1    Dai, X.2    Zhang, Z.3    Jiang, Y.4    Ma, X.5    Cai, X.6    Li, Y.7
  • 61
    • 85017105492 scopus 로고    scopus 로고
    • Proanthocyanidins affects the neurotoxicity of Abeta25-35 on C57/bl6 mice
    • [PubMed]
    • He, Q.; Yang, S.Y.; Wang, W.; Wu, Z.J.; Ma, H.L.; Lu, Y. Proanthocyanidins affects the neurotoxicity of Abeta25-35 on C57/bl6 mice. Eur. Rev. Med. Pharmacol. Sci. 2016, 20, 679-684. [PubMed]
    • (2016) Eur. Rev. Med. Pharmacol. Sci , vol.20 , pp. 679-684
    • He, Q.1    Yang, S.Y.2    Wang, W.3    Wu, Z.J.4    Ma, H.L.5    Lu, Y.6
  • 62
    • 0344442350 scopus 로고    scopus 로고
    • Hydrogen peroxide-induced apoptosis in pc12 cells and the protective effect of puerarin
    • CrossRef] [PubMed]
    • Jiang, B.; Liu, J.H.; Bao, Y.M.; An, L.J. Hydrogen peroxide-induced apoptosis in pc12 cells and the protective effect of puerarin. Cell Biol. Int. 2003, 27, 1025-1031. [CrossRef] [PubMed]
    • (2003) Cell Biol. Int. , vol.27 , pp. 1025-1031
    • Jiang, B.1    Liu, J.H.2    Bao, Y.M.3    An, L.J.4
  • 63
    • 84963532776 scopus 로고    scopus 로고
    • Protective effect of puerarin against oxidative stress injury of neural cells and related mechanisms
    • CrossRef] [PubMed]
    • Cheng, Y.; Leng, W.; Zhang, J. Protective effect of puerarin against oxidative stress injury of neural cells and related mechanisms. Med. Sci. Monit. 2016, 22, 1244-1249. [CrossRef] [PubMed]
    • (2016) Med. Sci. Monit. , vol.22 , pp. 1244-1249
    • Cheng, Y.1    Leng, W.2    Zhang, J.3
  • 64
    • 79957873239 scopus 로고    scopus 로고
    • Neuroprotective effects of puerarin against beta-amyloid-induced neurotoxicity in PC12 cells via a PI3K-dependent signaling pathway
    • CrossRef] [PubMed]
    • Xing, G.; Dong, M.; Li, X.; Zou, Y.; Fan, L.; Wang, X.; Cai, D.; Li, C.; Zhou, L.; Liu, J. et al. Neuroprotective effects of puerarin against beta-amyloid-induced neurotoxicity in PC12 cells via a PI3K-dependent signaling pathway. Brain Res. Bull. 2011, 85, 212-218. [CrossRef] [PubMed]
    • (2011) Brain Res. Bull. , vol.85 , pp. 212-218
    • Xing, G.1    Dong, M.2    Li, X.3    Zou, Y.4    Fan, L.5    Wang, X.6    Cai, D.7    Li, C.8    Zhou, L.9    Liu, J.10
  • 65
    • 84870798936 scopus 로고    scopus 로고
    • Protective effect of puerarin against beta-amyloid-induced oxidative stress in neuronal cultures from rat hippocampus: Involvement of the GSK-3beta/Nrf2 signaling pathway
    • CrossRef] [PubMed]
    • Zou, Y.; Hong, B.; Fan, L.; Zhou, L.; Liu, Y.; Wu, Q.; Zhang, X.; Dong, M. Protective effect of puerarin against beta-amyloid-induced oxidative stress in neuronal cultures from rat hippocampus: Involvement of the GSK-3beta/Nrf2 signaling pathway. Free Radic. Res. 2013, 47, 55-63. [CrossRef] [PubMed]
    • (2013) Free Radic. Res , vol.47 , pp. 55-63
    • Zou, Y.1    Hong, B.2    Fan, L.3    Zhou, L.4    Liu, Y.5    Wu, Q.6    Zhang, X.7    Dong, M.8
  • 66
    • 84904096814 scopus 로고    scopus 로고
    • Puerarin alleviates neuropathic pain by inhibiting neuroinflammation in spinal cord
    • CrossRef] [PubMed]
    • Liu, M.; Liao, K.; Yu, C.; Li, X.; Liu, S.; Yang, S. Puerarin alleviates neuropathic pain by inhibiting neuroinflammation in spinal cord. Mediat. Inflamm. 2014, 2014, 485927. [CrossRef] [PubMed]
    • (2014) Mediat. Inflamm , vol.2014
    • Liu, M.1    Liao, K.2    Yu, C.3    Li, X.4    Liu, S.5    Yang, S.6
  • 67
    • 84866756397 scopus 로고    scopus 로고
    • Quercetin protects neuroblastoma SH-SY5Y cells against oxidative stress by inhibiting expression of kruppel-like factor 4
    • CrossRef] [PubMed]
    • Xi, J.; Zhang, B.; Luo, F.; Liu, J.; Yang, T. Quercetin protects neuroblastoma SH-SY5Y cells against oxidative stress by inhibiting expression of kruppel-like factor 4. Neurosci. Lett. 2012, 527, 115-120. [CrossRef] [PubMed]
    • (2012) Neurosci. Lett , vol.527 , pp. 115-120
    • Xi, J.1    Zhang, B.2    Luo, F.3    Liu, J.4    Yang, T.5
  • 68
    • 84883658207 scopus 로고    scopus 로고
    • Quercetin protects rat dorsal root ganglion neurons against high glucose-induced injury in vitro through NRF-2/HO-1 activation and NF-kB inhibition
    • CrossRef] [PubMed]
    • Shi, Y.; Liang, X.C.; Zhang, H.; Wu, Q.L.; Qu, L.; Sun, Q. Quercetin protects rat dorsal root ganglion neurons against high glucose-induced injury in vitro through NRF-2/HO-1 activation and NF-kB inhibition. Acta Pharmacol. Sin. 2013, 34, 1140-1148. [CrossRef] [PubMed]
    • (2013) Acta Pharmacol. Sin , vol.34 , pp. 1140-1148
    • Shi, Y.1    Liang, X.C.2    Zhang, H.3    Wu, Q.L.4    Qu, L.5    Sun, Q.6
  • 69
    • 84904328439 scopus 로고    scopus 로고
    • Quercetin alleviates high glucose-induced schwann cell damage by autophagy
    • CrossRef] [PubMed]
    • Qu, L.; Liang, X.; Gu, B.; Liu, W. Quercetin alleviates high glucose-induced schwann cell damage by autophagy. Neural Regen. Res. 2014, 9, 1195-1203. [CrossRef] [PubMed]
    • (2014) Neural Regen. Res , vol.9 , pp. 1195-1203
    • Qu, L.1    Liang, X.2    Gu, B.3    Liu, W.4
  • 70
    • 84055207546 scopus 로고    scopus 로고
    • Growth-promoting effects of quercetin on peripheral nerves in rats
    • CrossRef] [PubMed]
    • Wang, W.; Huang, C.Y.; Tsai, F.J.; Tsai, C.C.; Yao, C.H.; Chen, Y.S. Growth-promoting effects of quercetin on peripheral nerves in rats. Int. J. Artif. Organs 2011, 34, 1095-1105. [CrossRef] [PubMed]
    • (2011) Int. J. Artif. Organs , vol.34 , pp. 1095-1105
    • Wang, W.1    Huang, C.Y.2    Tsai, F.J.3    Tsai, C.C.4    Yao, C.H.5    Chen, Y.S.6
  • 71
    • 84918793976 scopus 로고    scopus 로고
    • Differential effects of quercetin on hippocampus-dependent learning and memory in mice fed with different diets related with oxidative stress
    • CrossRef] [PubMed]
    • Xia, S.F.; Xie, Z.X.; Qiao, Y.; Li, L.R.; Cheng, X.R.; Tang, X.; Shi, Y.H.; Le, G.W. Differential effects of quercetin on hippocampus-dependent learning and memory in mice fed with different diets related with oxidative stress. Physiol. Behav. 2015, 138, 325-331. [CrossRef] [PubMed]
    • (2015) Physiol. Behav , vol.138 , pp. 325-331
    • Xia, S.F.1    Xie, Z.X.2    Qiao, Y.3    Li, L.R.4    Cheng, X.R.5    Tang, X.6    Shi, Y.H.7    Le, G.W.8
  • 72
    • 33645103657 scopus 로고    scopus 로고
    • Antihyperglycaemic and antioxidant effect of rutin, a polyphenolic flavonoid, in streptozotocin-induced diabetic wistar rats
    • CrossRef] [PubMed]
    • Kamalakkannan, N.; Prince, P.S. Antihyperglycaemic and antioxidant effect of rutin, a polyphenolic flavonoid, in streptozotocin-induced diabetic wistar rats. Basic Clin. Pharmacol. Toxicol. 2006, 98, 97-103. [CrossRef] [PubMed]
    • (2006) Basic Clin. Pharmacol. Toxicol , vol.98 , pp. 97-103
    • Kamalakkannan, N.1    Prince, P.S.2
  • 73
    • 84950136414 scopus 로고    scopus 로고
    • Rutin ameliorates diabetic neuropathy by lowering plasma glucose and decreasing oxidative stress via nrf2 signaling pathway in rats
    • CrossRef] [PubMed]
    • Tian, R.; Yang, W.; Xue, Q.; Gao, L.; Huo, J.; Ren, D.; Chen, X. Rutin ameliorates diabetic neuropathy by lowering plasma glucose and decreasing oxidative stress via nrf2 signaling pathway in rats. Eur. J. Pharmacol. 2016, 771, 84-92. [CrossRef] [PubMed]
    • (2016) Eur. J. Pharmacol , vol.771 , pp. 84-92
    • Tian, R.1    Yang, W.2    Xue, Q.3    Gao, L.4    Huo, J.5    Ren, D.6    Chen, X.7
  • 74
    • 79951581293 scopus 로고    scopus 로고
    • Silibinin: A novel inhibitor of abeta aggregation
    • CrossRef] [PubMed]
    • Yin, F.; Liu, J.; Ji, X.; Wang, Y.; Zidichouski, J.; Zhang, J. Silibinin: A novel inhibitor of abeta aggregation. Neurochem. Int. 2011, 58, 399-403. [CrossRef] [PubMed]
    • (2011) Neurochem. Int , vol.58 , pp. 399-403
    • Yin, F.1    Liu, J.2    Ji, X.3    Wang, Y.4    Zidichouski, J.5    Zhang, J.6
  • 75
    • 84958108264 scopus 로고    scopus 로고
    • Silibinin prevents autophagic cell death upon oxidative stress in cortical neurons and cerebral ischemia-reperfusion injury
    • CrossRef] [PubMed]
    • Wang, M.; Li, Y.J.; Ding, Y.; Zhang, H.N.; Sun, T.; Zhang, K.; Yang, L.; Guo, Y.Y.; Liu, S.B.; Zhao, M.G. et al. Silibinin prevents autophagic cell death upon oxidative stress in cortical neurons and cerebral ischemia-reperfusion injury. Mol. Neurobiol. 2016, 53, 932-943. [CrossRef] [PubMed]
    • (2016) Mol. Neurobiol , vol.53 , pp. 932-943
    • Wang, M.1    Li, Y.J.2    Ding, Y.3    Zhang, H.N.4    Sun, T.5    Zhang, K.6    Yang, L.7    Guo, Y.Y.8    Liu, S.B.9    Zhao, M.G.10
  • 77
    • 33845546972 scopus 로고    scopus 로고
    • Hyperglycemia inhibits retinoic acid-induced activation of rac1, prevents differentiation of cortical neurons, and causes oxidative stress in a rat model of diabetic pregnancy
    • CrossRef] [PubMed]
    • Guleria, R.S.; Pan, J.; Dipette, D.; Singh, U.S. Hyperglycemia inhibits retinoic acid-induced activation of rac1, prevents differentiation of cortical neurons, and causes oxidative stress in a rat model of diabetic pregnancy. Diabetes 2006, 55, 3326-3334. [CrossRef] [PubMed]
    • (2006) Diabetes , vol.55 , pp. 3326-3334
    • Guleria, R.S.1    Pan, J.2    Dipette, D.3    Singh, U.S.4
  • 79
    • 33745886526 scopus 로고    scopus 로고
    • Ascorbic acid protects SH-SY5Y neuroblastoma cells from apoptosis and death induced by beta-amyloid
    • CrossRef] [PubMed]
    • Huang, J.; May, J.M. Ascorbic acid protects SH-SY5Y neuroblastoma cells from apoptosis and death induced by beta-amyloid. Brain Res. 2006, 1097, 52-58. [CrossRef] [PubMed]
    • (2006) Brain Res , vol.1097 , pp. 52-58
    • Huang, J.1    May, J.M.2
  • 80
    • 84907854331 scopus 로고    scopus 로고
    • Ascorbic acid prevents high glucose-induced apoptosis in human brain pericytes
    • CrossRef] [PubMed]
    • May, J.M.; Jayagopal, A.; Qu, Z.C.; Parker, W.H. Ascorbic acid prevents high glucose-induced apoptosis in human brain pericytes. Biochem. Biophys. Res. Commun. 2014, 452, 112-117. [CrossRef] [PubMed]
    • (2014) Biochem. Biophys. Res. Commun , vol.452 , pp. 112-117
    • May, J.M.1    Jayagopal, A.2    Qu, Z.C.3    Parker, W.H.4
  • 81
    • 0028009686 scopus 로고
    • Chronic 1,25-dihydroxyvitamin D3-mediated induction of nerve growth factor mRNA and protein in l929 fibroblasts and in adult rat brain
    • CrossRef]
    • Saporito, M.S.; Brown, E.R.; Hartpence, K.C.; Wilcox, H.M.; Vaught, J.L.; Carswell, S. Chronic 1,25-dihydroxyvitamin D3-mediated induction of nerve growth factor mRNA and protein in l929 fibroblasts and in adult rat brain. Brain Res. 1994, 633, 189-196. [CrossRef]
    • (1994) Brain Res , vol.633 , pp. 189-196
    • Saporito, M.S.1    Brown, E.R.2    Hartpence, K.C.3    Wilcox, H.M.4    Vaught, J.L.5    Carswell, S.6
  • 82
    • 0028670779 scopus 로고
    • 1,25-dihydroxyvitamin D3 regulates NT-3, NT-4 but not bdnf mrna in astrocytes
    • CrossRef] [PubMed]
    • Neveu, I.; Naveilhan, P.; Baudet, C.; Brachet, P.; Metsis, M. 1,25-dihydroxyvitamin D3 regulates NT-3, NT-4 but not bdnf mrna in astrocytes. Neuroreport 1994, 6, 124-126. [CrossRef] [PubMed]
    • (1994) Neuroreport , vol.6 , pp. 124-126
    • Neveu, I.1    Naveilhan, P.2    Baudet, C.3    Brachet, P.4    Metsis, M.5
  • 83
    • 0029825776 scopus 로고    scopus 로고
    • 1,25-dihydroxyvitamin D3, an inducer of glial cell line-derived neurotrophic factor
    • CrossRef] [PubMed]
    • Naveilhan, P.; Neveu, I.; Wion, D.; Brachet, P. 1,25-dihydroxyvitamin D3, an inducer of glial cell line-derived neurotrophic factor. Neuroreport 1996, 7, 2171-2175. [CrossRef] [PubMed]
    • (1996) Neuroreport , vol.7 , pp. 2171-2175
    • Naveilhan, P.1    Neveu, I.2    Wion, D.3    Brachet, P.4
  • 84
    • 0032708935 scopus 로고    scopus 로고
    • A vitamin D(3) derivative (CB1093) induces nerve growth factor and prevents neurotrophic deficits in streptozotocin-diabetic rats
    • CrossRef] [PubMed]
    • Riaz, S.; Malcangio, M.; Miller, M.; Tomlinson, D.R. A vitamin D(3) derivative (CB1093) induces nerve growth factor and prevents neurotrophic deficits in streptozotocin-diabetic rats. Diabetologia 1999, 42, 1308-1313. [CrossRef] [PubMed]
    • (1999) Diabetologia , vol.42 , pp. 1308-1313
    • Riaz, S.1    Malcangio, M.2    Miller, M.3    Tomlinson, D.R.4
  • 85
    • 0034026089 scopus 로고    scopus 로고
    • Vitamin E protects neurons against oxidative cell death in vitro more effectively than 17-beta estradiol and induces the activity of the transcription factor NF-kappaB
    • CrossRef] [PubMed]
    • Behl, C. Vitamin E protects neurons against oxidative cell death in vitro more effectively than 17-beta estradiol and induces the activity of the transcription factor NF-kappaB. J. Neural. Transm. 2000, 107, 393-407. [CrossRef] [PubMed]
    • (2000) J. Neural. Transm , vol.107 , pp. 393-407
    • Behl, C.1
  • 87
    • 0037955858 scopus 로고    scopus 로고
    • Oxidant regulation of gene expression and neural tube development: Insights gained from diabetic pregnancy on molecular causes of neural tube defects
    • [PubMed]
    • Chang, T.I.; Horal, M.; Jain, S.K.; Wang, F.; Patel, R.; Loeken, M.R. Oxidant regulation of gene expression and neural tube development: Insights gained from diabetic pregnancy on molecular causes of neural tube defects. Diabetologia 2003, 46, 538-545. [PubMed]
    • (2003) Diabetologia , vol.46 , pp. 538-545
    • Chang, T.I.1    Horal, M.2    Jain, S.K.3    Wang, F.4    Patel, R.5    Loeken, M.R.6
  • 88
    • 12244299849 scopus 로고    scopus 로고
    • Increase of glial fibrillary acidic protein and S-100B in hippocampus and cortex of diabetic rats: Effects of vitamin E
    • CrossRef]
    • Baydas, G.; Nedzvetskii, V.S.; Tuzcu, M.; Yasar, A.; Kirichenko, S.V. Increase of glial fibrillary acidic protein and S-100B in hippocampus and cortex of diabetic rats: Effects of vitamin E. Eur. J. Pharmacol. 2003, 462, 67-71. [CrossRef]
    • (2003) Eur. J. Pharmacol , vol.462 , pp. 67-71
    • Baydas, G.1    Nedzvetskii, V.S.2    Tuzcu, M.3    Yasar, A.4    Kirichenko, S.V.5
  • 90
    • 0142215549 scopus 로고    scopus 로고
    • Modulation of the activity of pro-inflammatory enzymes, COX-2 and inos, by chrysin derivatives
    • CrossRef]
    • Cho, H.; Yun, C.W.; Park, W.K.; Kong, J.Y.; Kim, K.S.; Park, Y.; Lee, S.; Kim, B.K. Modulation of the activity of pro-inflammatory enzymes, COX-2 and inos, by chrysin derivatives. Pharmacol. Res. 2004, 49, 37-43. [CrossRef]
    • (2004) Pharmacol. Res. , vol.49 , pp. 37-43
    • Cho, H.1    Yun, C.W.2    Park, W.K.3    Kong, J.Y.4    Kim, K.S.5    Park, Y.6    Lee, S.7    Kim, B.K.8
  • 91
    • 1842790912 scopus 로고    scopus 로고
    • Neuroprotective effects of flavones on hydrogen peroxide-induced apoptosis in SH-SY5Y neuroblostoma cells
    • CrossRef] [PubMed]
    • Kang, S.S.; Lee, J.Y.; Choi, Y.K.; Kim, G.S.; Han, B.H. Neuroprotective effects of flavones on hydrogen peroxide-induced apoptosis in SH-SY5Y neuroblostoma cells. Bioorg. Med. Chem. Lett. 2004, 14, 2261-2264. [CrossRef] [PubMed]
    • (2004) Bioorg. Med. Chem. Lett , vol.14 , pp. 2261-2264
    • Kang, S.S.1    Lee, J.Y.2    Choi, Y.K.3    Kim, G.S.4    Han, B.H.5
  • 92
    • 52049102256 scopus 로고    scopus 로고
    • Structural requirements for the flavonoid fisetin in inhibiting fibril formation of amyloid beta protein
    • CrossRef] [PubMed]
    • Akaishi, T.; Morimoto, T.; Shibao, M.; Watanabe, S.; Sakai-Kato, K.; Utsunomiya-Tate, N.; Abe, K. Structural requirements for the flavonoid fisetin in inhibiting fibril formation of amyloid beta protein. Neurosci. Lett. 2008, 444, 280-285. [CrossRef] [PubMed]
    • (2008) Neurosci. Lett , vol.444 , pp. 280-285
    • Akaishi, T.1    Morimoto, T.2    Shibao, M.3    Watanabe, S.4    Sakai-Kato, K.5    Utsunomiya-Tate, N.6    Abe, K.7
  • 93
    • 50449111165 scopus 로고    scopus 로고
    • Update on uses and properties of citrus flavonoids: New findings in anticancer, cardiovascular, and anti-inflammatory activity
    • CrossRef] [PubMed]
    • Benavente-Garcia, O.; Castillo, J. Update on uses and properties of citrus flavonoids: New findings in anticancer, cardiovascular, and anti-inflammatory activity. J. Agric. Food Chem. 2008, 56, 6185-6205. [CrossRef] [PubMed]
    • (2008) J. Agric. Food Chem. , vol.56 , pp. 6185-6205
    • Benavente-Garcia, O.1    Castillo, J.2
  • 94
    • 0032692502 scopus 로고    scopus 로고
    • The effect of flavonoid treatment on the glycation and antioxidant status in type 1 diabetic patients
    • [PubMed]
    • Manuel y Keenoy, B.; Vertommen, J.; de Leeuw, I. The effect of flavonoid treatment on the glycation and antioxidant status in type 1 diabetic patients. Diabetes Nutr. Metab. 1999, 12, 256-263. [PubMed]
    • (1999) Diabetes Nutr. Metab , vol.12 , pp. 256-263
    • Keenoy, B.1    Vertommen, J.2    De Leeuw, I.3
  • 95
    • 77957790563 scopus 로고    scopus 로고
    • Dual beneficial effects of (-)-epigallocatechin-3-gallate on levodopa methylation and hippocampal neurodegeneration: In vitro and in vivo studies
    • CrossRef] [PubMed]
    • Kang, K.S.; Wen, Y.; Yamabe, N.; Fukui, M.; Bishop, S.C.; Zhu, B.T. Dual beneficial effects of (-)-epigallocatechin-3-gallate on levodopa methylation and hippocampal neurodegeneration: In vitro and in vivo studies. PLoS ONE 2010, 5, e11951. [CrossRef] [PubMed]
    • (2010) Plos ONE , vol.5
    • Kang, K.S.1    Wen, Y.2    Yamabe, N.3    Fukui, M.4    Bishop, S.C.5    Zhu, B.T.6
  • 96
    • 33846566792 scopus 로고    scopus 로고
    • Simultaneous analysis of eight bioactive compounds in danning tablet by HPLC-ESI-MS and HPLC-UV
    • CrossRef] [PubMed]
    • Liu, R.; Zhang, J.; Liang, M.; Zhang, W.; Yan, S.; Lin, M. Simultaneous analysis of eight bioactive compounds in danning tablet by HPLC-ESI-MS and HPLC-UV. J. Pharm. Biomed. Anal. 2007, 43, 1007-1012. [CrossRef] [PubMed]
    • (2007) J. Pharm. Biomed. Anal. , vol.43 , pp. 1007-1012
    • Liu, R.1    Zhang, J.2    Liang, M.3    Zhang, W.4    Yan, S.5    Lin, M.6
  • 97
    • 0028036694 scopus 로고
    • Biological effects of hesperidin, a citrus flavonoid. (note I): Antiinflammatory and analgesic activity
    • [PubMed]
    • Galati, E.M.; Monforte, M.T.; Kirjavainen, S.; Forestieri, A.M.; Trovato, A.; Tripodo, M.M. Biological effects of hesperidin, a citrus flavonoid. (note I): Antiinflammatory and analgesic activity. Farmaco 1994, 40, 709-712. [PubMed]
    • (1994) Farmaco , vol.40 , pp. 709-712
    • Galati, E.M.1    Monforte, M.T.2    Kirjavainen, S.3    Forestieri, A.M.4    Trovato, A.5    Tripodo, M.M.6
  • 98
    • 0028810911 scopus 로고
    • Biological effects of hesperidin, a citrus flavonoid. (note II): Hypolipidemic activity on experimental hypercholesterolemia in rat
    • [PubMed]
    • Monforte, M.T.; Trovato, A.; Kirjavainen, S.; Forestieri, A.M.; Galati, E.M.; Lo Curto, R.B. Biological effects of hesperidin, a citrus flavonoid. (note II): Hypolipidemic activity on experimental hypercholesterolemia in rat. Farmaco 1995, 50, 595-599. [PubMed]
    • (1995) Farmaco , vol.50 , pp. 595-599
    • Monforte, M.T.1    Trovato, A.2    Kirjavainen, S.3    Forestieri, A.M.4    Galati, E.M.5    Lo Curto, R.B.6
  • 99
    • 77249130723 scopus 로고    scopus 로고
    • Protective effects of kaempferol (3,41,5,7-tetrahydroxyflavone) against amyloid beta peptide (Abeta)-induced neurotoxicity in ICR mice
    • CrossRef] [PubMed]
    • Kim, J.K.; Choi, S.J.; Cho, H.Y.; Hwang, H.J.; Kim, Y.J.; Lim, S.T.; Kim, C.J.; Kim, H.K.; Peterson, S.; Shin, D.H. Protective effects of kaempferol (3,41,5,7-tetrahydroxyflavone) against amyloid beta peptide (Abeta)-induced neurotoxicity in ICR mice. Biosci. Biotechnol. Biochem. 2010, 74, 397-401. [CrossRef] [PubMed]
    • (2010) Biosci. Biotechnol. Biochem , vol.74 , pp. 397-401
    • Kim, J.K.1    Choi, S.J.2    Cho, H.Y.3    Hwang, H.J.4    Kim, Y.J.5    Lim, S.T.6    Kim, C.J.7    Kim, H.K.8    Peterson, S.9    Shin, D.H.10
  • 100
    • 84921979811 scopus 로고    scopus 로고
    • Extracts and compounds with anti-diabetic complications and anti-cancer activity from castanea mollissina blume (Chinese chestnut)
    • CrossRef] [PubMed]
    • Zhang, L.; Gao, H.Y.; Baba, M.; Okada, Y.; Okuyama, T.; Wu, L.J.; Zhan, L.B. Extracts and compounds with anti-diabetic complications and anti-cancer activity from castanea mollissina blume (Chinese chestnut). BMC Complement. Altern. Med. 2014, 14, 422. [CrossRef] [PubMed]
    • (2014) BMC Complement. Altern. Med. , vol.14 , pp. 422
    • Zhang, L.1    Gao, H.Y.2    Baba, M.3    Okada, Y.4    Okuyama, T.5    Wu, L.J.6    Zhan, L.B.7
  • 101
    • 12844272321 scopus 로고    scopus 로고
    • Polyphenols and disease risk in epidemiologic studies
    • [PubMed]
    • Arts, I.C.; Hollman, P.C. Polyphenols and disease risk in epidemiologic studies. Am. J. Clin. Nutr. 2005, 81, 317S-325S. [PubMed]
    • (2005) Am. J. Clin. Nutr , vol.81 , pp. 317S-325S
    • Arts, I.C.1    Hollman, P.C.2
  • 102
    • 84880823145 scopus 로고    scopus 로고
    • Protective effect of luteolin on an oxidative-stress model induced by microinjection of sodium nitroprusside in mice
    • CrossRef]
    • Nazari, Q.A.; Kume, T.; Takada-Takatori, Y.; Izumi, Y.; Akaike, A. Protective effect of luteolin on an oxidative-stress model induced by microinjection of sodium nitroprusside in mice. J. Pharm. Sci. 2013, 122, 109-117. [CrossRef]
    • (2013) J. Pharm. Sci , vol.122 , pp. 109-117
    • Nazari, Q.A.1    Kume, T.2    Takada-Takatori, Y.3    Izumi, Y.4    Akaike, A.5
  • 103
    • 84936752993 scopus 로고    scopus 로고
    • Luteolin attenuate the D-galactose-induced renal damage by attenuation of oxidative stress and inflammation
    • CrossRef] [PubMed]
    • Xu, Y.; Zhang, J.; Liu, J.; Li, S.; Li, C.; Wang, W.; Ma, R.; Liu, Y. Luteolin attenuate the D-galactose-induced renal damage by attenuation of oxidative stress and inflammation. Nat. Prod. Res. 2015, 29, 1078-1082. [CrossRef] [PubMed]
    • (2015) Nat. Prod. Res. , vol.29 , pp. 1078-1082
    • Xu, Y.1    Zhang, J.2    Liu, J.3    Li, S.4    Li, C.5    Wang, W.6    Ma, R.7    Liu, Y.8
  • 105
    • 0036827673 scopus 로고    scopus 로고
    • Interactions of flavonoids with iron and copper ions: A mechanism for their antioxidant activity
    • CrossRef] [PubMed]
    • Mira, L.; Fernandez, M.T.; Santos, M.; Rocha, R.; Florencio, M.H.; Jennings, K.R. Interactions of flavonoids with iron and copper ions: A mechanism for their antioxidant activity. Free Radic. Res. 2002, 36, 1199-1208. [CrossRef] [PubMed]
    • (2002) Free Radic. Res , vol.36 , pp. 1199-1208
    • Mira, L.1    Fernandez, M.T.2    Santos, M.3    Rocha, R.4    Florencio, M.H.5    Jennings, K.R.6
  • 106
    • 0031090642 scopus 로고    scopus 로고
    • Nature’s own pharmacy: The diabetes perspective
    • CrossRef] [PubMed]
    • Gray, A.M.; Flatt, P.R. Nature’s own pharmacy: The diabetes perspective. Proc. Nutr. Soc. 1997, 56, 507-517. [CrossRef] [PubMed]
    • (1997) Proc. Nutr. Soc , vol.56 , pp. 507-517
    • Gray, A.M.1    Flatt, P.R.2
  • 107
    • 0042309869 scopus 로고    scopus 로고
    • Aldose reductase inhibitors from the nature
    • CrossRef] [PubMed]
    • Kawanishi, K.; Ueda, H.; Moriyasu, M. Aldose reductase inhibitors from the nature. Curr. Med. Chem. 2003, 10, 1353-1374. [CrossRef] [PubMed]
    • (2003) Curr. Med. Chem , vol.10 , pp. 1353-1374
    • Kawanishi, K.1    Ueda, H.2    Moriyasu, M.3
  • 108
    • 33947679408 scopus 로고    scopus 로고
    • Flavonoids inhibit the formation of the cross-linking AGE pentosidine in collagen incubated with glucose, according to their structure
    • CrossRef] [PubMed]
    • Urios, P.; Grigorova-Borsos, A.M.; Sternberg, M. Flavonoids inhibit the formation of the cross-linking AGE pentosidine in collagen incubated with glucose, according to their structure. Eur. J. Nutr. 2007, 46, 139-146. [CrossRef] [PubMed]
    • (2007) Eur. J. Nutr , vol.46 , pp. 139-146
    • Urios, P.1    Grigorova-Borsos, A.M.2    Sternberg, M.3
  • 109
    • 84908074460 scopus 로고    scopus 로고
    • Ameliorative effect of myricetin on insulin resistance in mice fed a high-fat, high-sucrose diet
    • CrossRef] [PubMed]
    • Choi, H.N.; Kang, M.J.; Lee, S.J.; Kim, J.I. Ameliorative effect of myricetin on insulin resistance in mice fed a high-fat, high-sucrose diet. Nutr. Res. Pract. 2014, 8, 544-549. [CrossRef] [PubMed]
    • (2014) Nutr. Res. Pract , vol.8 , pp. 544-549
    • Choi, H.N.1    Kang, M.J.2    Lee, S.J.3    Kim, J.I.4
  • 110
    • 23644438869 scopus 로고    scopus 로고
    • Myricetin as the active principle of abelmoschus moschatus to lower plasma glucose in streptozotocin-induced diabetic rats
    • CrossRef] [PubMed]
    • Liu, I.M.; Liou, S.S.; Lan, T.W.; Hsu, F.L.; Cheng, J.T. Myricetin as the active principle of abelmoschus moschatus to lower plasma glucose in streptozotocin-induced diabetic rats. Planta Med. 2005, 71, 617-621. [CrossRef] [PubMed]
    • (2005) Planta Med , vol.71 , pp. 617-621
    • Liu, I.M.1    Liou, S.S.2    Lan, T.W.3    Hsu, F.L.4    Cheng, J.T.5
  • 111
    • 0026674117 scopus 로고
    • The formalin test: An evaluation of the method
    • CrossRef]
    • Tjolsen, A.; Berge, O.G.; Hunskaar, S.; Rosland, J.H.; Hole, K. The formalin test: An evaluation of the method. Pain 1992, 51, 5-17. [CrossRef]
    • (1992) Pain , vol.51 , pp. 5-17
    • Tjolsen, A.1    Berge, O.G.2    Hunskaar, S.3    Rosland, J.H.4    Hole, K.5
  • 112
    • 0036303144 scopus 로고    scopus 로고
    • Elevated spinal cyclooxygenase and prostaglandin release during hyperalgesia in diabetic rats
    • CrossRef] [PubMed]
    • Freshwater, J.D.; Svensson, C.I.; Malmberg, A.B.; Calcutt, N.A. Elevated spinal cyclooxygenase and prostaglandin release during hyperalgesia in diabetic rats. Diabetes 2002, 51, 2249-2255. [CrossRef] [PubMed]
    • (2002) Diabetes , vol.51 , pp. 2249-2255
    • Freshwater, J.D.1    Svensson, C.I.2    Malmberg, A.B.3    Calcutt, N.A.4
  • 113
    • 70349481938 scopus 로고    scopus 로고
    • Treatment of neuropathic pain: An overview of recent guidelines
    • CrossRef] [PubMed]
    • O’Connor, A.B.; Dworkin, R.H. Treatment of neuropathic pain: An overview of recent guidelines. Am. J. Med. 2009, 122, S22-S32. [CrossRef] [PubMed]
    • (2009) Am. J. Med , vol.122 , pp. S22-S32
    • O’Connor, A.B.1    Dworkin, R.H.2
  • 114
    • 84867308972 scopus 로고    scopus 로고
    • Participation of antioxidant and cholinergic system in protective effect of naringenin against type-2 diabetes-induced memory dysfunction in rats
    • CrossRef] [PubMed]
    • Rahigude, A.; Bhutada, P.; Kaulaskar, S.; Aswar, M.; Otari, K. Participation of antioxidant and cholinergic system in protective effect of naringenin against type-2 diabetes-induced memory dysfunction in rats. Neuroscience 2012, 226, 62-72. [CrossRef] [PubMed]
    • (2012) Neuroscience , vol.226 , pp. 62-72
    • Rahigude, A.1    Bhutada, P.2    Kaulaskar, S.3    Aswar, M.4    Otari, K.5
  • 116
    • 0037132562 scopus 로고    scopus 로고
    • Grape seed proanthocyanidins prevent plasma postprandial oxidative stress in humans
    • CrossRef] [PubMed]
    • Natella, F.; Belelli, F.; Gentili, V.; Ursini, F.; Scaccini, C. Grape seed proanthocyanidins prevent plasma postprandial oxidative stress in humans. J. Agric. Food Chem. 2002, 50, 7720-7725. [CrossRef] [PubMed]
    • (2002) J. Agric. Food Chem , vol.50 , pp. 7720-7725
    • Natella, F.1    Belelli, F.2    Gentili, V.3    Ursini, F.4    Scaccini, C.5
  • 117
    • 2942590320 scopus 로고    scopus 로고
    • Identification of puerarin and its metabolites in rats by liquid chromatography-tandem mass spectrometry
    • CrossRef] [PubMed]
    • Prasain, J.K.; Jones, K.; Brissie, N.; Moore, R.; Wyss, J.M.; Barnes, S. Identification of puerarin and its metabolites in rats by liquid chromatography-tandem mass spectrometry. J. Agric. Food Chem. 2004, 52, 3708-3712. [CrossRef] [PubMed]
    • (2004) J. Agric. Food Chem. , vol.52 , pp. 3708-3712
    • Prasain, J.K.1    Jones, K.2    Brissie, N.3    Moore, R.4    Wyss, J.M.5    Barnes, S.6
  • 118
    • 52949146386 scopus 로고    scopus 로고
    • Puerarin protects PC12 cells against beta-amyloid-induced cell injury
    • CrossRef] [PubMed]
    • Zhang, H.Y.; Liu, Y.H.; Wang, H.Q.; Xu, J.H.; Hu, H.T. Puerarin protects PC12 cells against beta-amyloid-induced cell injury. Cell. Biol. Int. 2008, 32, 1230-1237. [CrossRef] [PubMed]
    • (2008) Cell. Biol. Int , vol.32 , pp. 1230-1237
    • Zhang, H.Y.1    Liu, Y.H.2    Wang, H.Q.3    Xu, J.H.4    Hu, H.T.5
  • 119
    • 84907395018 scopus 로고    scopus 로고
    • Efficacy and safety of puerarin injection in treatment of diabetic peripheral neuropathy: A systematic review and meta-analysis of randomized controlled trials
    • CrossRef]
    • Wu, J.; Zhang, X.; Zhang, B. Efficacy and safety of puerarin injection in treatment of diabetic peripheral neuropathy: A systematic review and meta-analysis of randomized controlled trials. J. Tradit. Chin. Med. 2014, 34, 401-410. [CrossRef]
    • (2014) J. Tradit. Chin. Med , vol.34 , pp. 401-410
    • Wu, J.1    Zhang, X.2    Zhang, B.3
  • 121
    • 0029610477 scopus 로고
    • Review of the biology of quercetin and related bioflavonoidsFood
    • CrossRef]
    • Formica, J.V.; Regelson, W. Review of the biology of quercetin and related bioflavonoids. Food Chem. Toxicol. 1995, 33, 1061-1080. [CrossRef]
    • (1995) Chem. Toxicol , vol.33 , pp. 1061-1080
    • Formica, J.V.1    Regelson, W.2
  • 122
  • 123
    • 0141851856 scopus 로고    scopus 로고
    • Quercetin, a bioflavonoid, attenuates thermal hyperalgesia in a mouse model of diabetic neuropathic pain
    • CrossRef]
    • Anjaneyulu, M.; Chopra, K. Quercetin, a bioflavonoid, attenuates thermal hyperalgesia in a mouse model of diabetic neuropathic pain. Prog. Neuro-Psychopharmacol. Biol. Psychiatry 2003, 27, 1001-1005. [CrossRef]
    • (2003) Prog. Neuro-Psychopharmacol. Biol. Psychiatry , vol.27 , pp. 1001-1005
    • Anjaneyulu, M.1    Chopra, K.2
  • 124
    • 84885646002 scopus 로고    scopus 로고
    • Diabetic neuropathy: An evaluation of the use of quercetin in the cecum of rats. World
    • CrossRef] [PubMed]
    • Ferreira, P.E.; Lopes, C.R.; Alves, A.M.; Alves, E.P.; Linden, D.R.; Zanoni, J.N.; Buttow, N.C. Diabetic neuropathy: An evaluation of the use of quercetin in the cecum of rats. World J. Gastroenterol. 2013, 19, 6416-6426. [CrossRef] [PubMed]
    • (2013) J. Gastroenterol , vol.19 , pp. 6416-6426
    • Ferreira, P.E.1    Lopes, C.R.2    Alves, A.M.3    Alves, E.P.4    Linden, D.R.5    Zanoni, J.N.6    Buttow, N.C.7
  • 125
    • 23844553170 scopus 로고    scopus 로고
    • A multicenter, double-blind, safety study of QR-333 for the treatment of symptomatic diabetic peripheral neuropathy. A preliminary report
    • CrossRef] [PubMed]
    • Valensi, P.; Le Devehat, C.; Richard, J.L.; Farez, C.; Khodabandehlou, T.; Rosenbloom, R.A.; LeFante, C. A multicenter, double-blind, safety study of QR-333 for the treatment of symptomatic diabetic peripheral neuropathy. A preliminary report. J. Diabetes Complicat. 2005, 19, 247-253. [CrossRef] [PubMed]
    • (2005) J. Diabetes Complicat , vol.19 , pp. 247-253
    • Valensi, P.1    Le Devehat, C.2    Richard, J.L.3    Farez, C.4    Khodabandehlou, T.5    Rosenbloom, R.A.6    Lefante, C.7
  • 126
    • 0031721802 scopus 로고    scopus 로고
    • Polyphenols: Chemistry, dietary sources, metabolism, and nutritional significance
    • CrossRef] [PubMed]
    • Bravo, L. Polyphenols: Chemistry, dietary sources, metabolism, and nutritional significance. Nutr. Rev. 1998, 56, 317-333. [CrossRef] [PubMed]
    • (1998) Nutr. Rev , vol.56 , pp. 317-333
    • Bravo, L.1
  • 127
    • 84908698574 scopus 로고    scopus 로고
    • Review of the protective effects of rutin on the metabolic function as an important dietary flavonoid
    • CrossRef] [PubMed]
    • Hosseinzadeh, H.; Nassiri-Asl, M. Review of the protective effects of rutin on the metabolic function as an important dietary flavonoid. J. Endocrinol. Invest. 2014, 37, 783-788. [CrossRef] [PubMed]
    • (2014) J. Endocrinol. Invest , vol.37 , pp. 783-788
    • Hosseinzadeh, H.1    Nassiri-Asl, M.2
  • 128
    • 84930278768 scopus 로고    scopus 로고
    • Rutin alleviates prion peptide-induced cell death through inhibiting apoptotic pathway activation in dopaminergic neuronal cells
    • CrossRef] [PubMed]
    • Na, J.Y.; Kim, S.; Song, K.; Kwon, J. Rutin alleviates prion peptide-induced cell death through inhibiting apoptotic pathway activation in dopaminergic neuronal cells. Cell. Mol. Neurobiol. 2014, 34, 1071-1079. [CrossRef] [PubMed]
    • (2014) Cell. Mol. Neurobiol , vol.34 , pp. 1071-1079
    • Na, J.Y.1    Kim, S.2    Song, K.3    Kwon, J.4
  • 129
    • 84907372030 scopus 로고    scopus 로고
    • Rutin attenuates ethanol-induced neurotoxicity in hippocampal neuronal cells by increasing aldehyde dehydrogenase 2
    • CrossRef] [PubMed]
    • Song, K.; Kim, S.; Na, J.Y.; Park, J.H.; Kim, J.K.; Kim, J.H.; Kwon, J. Rutin attenuates ethanol-induced neurotoxicity in hippocampal neuronal cells by increasing aldehyde dehydrogenase 2. Food Chem. Toxicol. 2014, 72, 228-233. [CrossRef] [PubMed]
    • (2014) Food Chem. Toxicol , vol.72 , pp. 228-233
    • Song, K.1    Kim, S.2    Na, J.Y.3    Park, J.H.4    Kim, J.K.5    Kim, J.H.6    Kwon, J.7
  • 130
    • 0033955308 scopus 로고    scopus 로고
    • Antioxidants and herbal extracts protect HT-4 neuronal cells against glutamate-induced cytotoxicity
    • CrossRef] [PubMed]
    • Kobayashi, M.S.; Han, D.; Packer, L. Antioxidants and herbal extracts protect HT-4 neuronal cells against glutamate-induced cytotoxicity. Free Radic. Res. 2000, 32, 115-124. [CrossRef] [PubMed]
    • (2000) Free Radic. Res , vol.32 , pp. 115-124
    • Kobayashi, M.S.1    Han, D.2    Packer, L.3
  • 131
    • 80052947979 scopus 로고    scopus 로고
    • Neuroprotective effects of quercetin, rutin and okra (Abelmoschus esculentus Linn.) in dexamethasone-treated mice
    • CrossRef] [PubMed]
    • Tongjaroenbuangam, W.; Ruksee, N.; Chantiratikul, P.; Pakdeenarong, N.; Kongbuntad, W.; Govitrapong, P. Neuroprotective effects of quercetin, rutin and okra (Abelmoschus esculentus Linn.) in dexamethasone-treated mice. Neurochem. Int. 2011, 59, 677-685. [CrossRef] [PubMed]
    • (2011) Neurochem. Int. , vol.59 , pp. 677-685
    • Tongjaroenbuangam, W.1    Ruksee, N.2    Chantiratikul, P.3    Pakdeenarong, N.4    Kongbuntad, W.5    Govitrapong, P.6
  • 132
    • 84980344776 scopus 로고    scopus 로고
    • Protective effects of combined therapy of rutin with silymarin on experimentally induced diabetic neuropathy in rats
    • Alenazi, M.M.; Alkhamees, O.A.; Alroujayee, A.S.; Ahmed, M.M. Protective effects of combined therapy of rutin with silymarin on experimentally induced diabetic neuropathy in rats. Diabetic Med. 2014, 31, 57.
    • (2014) Diabetic Med , vol.31 , pp. 57
    • Alenazi, M.M.1    Alkhamees, O.A.2    Alroujayee, A.S.3    Ahmed, M.M.4
  • 133
    • 84947022268 scopus 로고    scopus 로고
    • Hesperidin and silibinin ameliorate aluminum-induced neurotoxicity: Modulation of antioxidants and inflammatory cytokines level in mice hippocampus
    • CrossRef] [PubMed]
    • Jangra, A.; Kasbe, P.; Pandey, S.N.; Dwivedi, S.; Gurjar, S.S.; Kwatra, M.; Mishra, M.; Venu, A.K.; Sulakhiya, K.; Gogoi, R. et al. Hesperidin and silibinin ameliorate aluminum-induced neurotoxicity: Modulation of antioxidants and inflammatory cytokines level in mice hippocampus. Biol. Trace Elem. Res. 2015, 168, 462-471. [CrossRef] [PubMed]
    • (2015) Biol. Trace Elem. Res. , vol.168 , pp. 462-471
    • Jangra, A.1    Kasbe, P.2    Pandey, S.N.3    Dwivedi, S.4    Gurjar, S.S.5    Kwatra, M.6    Mishra, M.7    Venu, A.K.8    Sulakhiya, K.9    Gogoi, R.10
  • 134
    • 84891702546 scopus 로고    scopus 로고
    • Silibinin pretreatment attenuates biochemical and behavioral changes induced by intrastriatal MPP+ injection in rats
    • CrossRef] [PubMed]
    • Geed, M.; Garabadu, D.; Ahmad, A.; Krishnamurthy, S. Silibinin pretreatment attenuates biochemical and behavioral changes induced by intrastriatal MPP+ injection in rats. Pharmacol. Biochem. Behav. 2014, 117, 92-103. [CrossRef] [PubMed]
    • (2014) Pharmacol. Biochem. Behav , vol.117 , pp. 92-103
    • Geed, M.1    Garabadu, D.2    Ahmad, A.3    Krishnamurthy, S.4
  • 135
    • 84925583817 scopus 로고    scopus 로고
    • Silibinin prevents dopaminergic neuronal loss in a mouse model of parkinson’s disease via mitochondrial stabilization
    • CrossRef] [PubMed]
    • Lee, Y.; Park, H.R.; Chun, H.J.; Lee, J. Silibinin prevents dopaminergic neuronal loss in a mouse model of parkinson’s disease via mitochondrial stabilization. J. Neurosci. Res. 2015, 93, 755-765. [CrossRef] [PubMed]
    • (2015) J. Neurosci. Res , vol.93 , pp. 755-765
    • Lee, Y.1    Park, H.R.2    Chun, H.J.3    Lee, J.4
  • 136
    • 46349090170 scopus 로고    scopus 로고
    • All-trans retinoic acid induces nerve regeneration and increases serum and nerve contents of neural growth factor in experimental diabetic neuropathy
    • CrossRef] [PubMed]
    • Hernandez-Pedro, N.; Ordonez, G.; Ortiz-Plata, A.; Palencia-Hernandez, G.; Garcia-Ulloa, A.C.; Flores-Estrada, D.; Sotelo, J.; Arrieta, O. All-trans retinoic acid induces nerve regeneration and increases serum and nerve contents of neural growth factor in experimental diabetic neuropathy. Transl. Res. 2008, 152, 31-37. [CrossRef] [PubMed]
    • (2008) Transl. Res , vol.152 , pp. 31-37
    • Hernandez-Pedro, N.1    Ordonez, G.2    Ortiz-Plata, A.3    Palencia-Hernandez, G.4    Garcia-Ulloa, A.C.5    Flores-Estrada, D.6    Sotelo, J.7    Arrieta, O.8
  • 138
    • 0034194081 scopus 로고    scopus 로고
    • Ascorbate regulation and its neuroprotective role in the brain
    • CrossRef]
    • Rice, M.E. Ascorbate regulation and its neuroprotective role in the brain. Trends Neurosci. 2000, 23, 209-216. [CrossRef]
    • (2000) Trends Neurosci , vol.23 , pp. 209-216
    • Rice, M.E.1
  • 139
    • 84875704668 scopus 로고    scopus 로고
    • Vitamin C transport and its role in the central nervous system
    • [PubMed]
    • May, J.M. Vitamin C transport and its role in the central nervous system. Subcell. Biochem. 2012, 56, 85-103. [PubMed]
    • (2012) Subcell. Biochem , vol.56 , pp. 85-103
    • May, J.M.1
  • 140
    • 60449102448 scopus 로고    scopus 로고
    • Function in the brain: Vital role of the ascorbate transporter SVCT2
    • CrossRef] [PubMed]
    • Harrison, F.E.; May, J.M. Vitamin C function in the brain: Vital role of the ascorbate transporter SVCT2. Free Radic. Biol. Med. 2009, 46, 719-730. [CrossRef] [PubMed]
    • (2009) Free Radic. Biol. Med , vol.46 , pp. 719-730
    • Harrison, F.E.1    May, J.M.2    Vitamin, C.3
  • 141
    • 85008670341 scopus 로고    scopus 로고
    • L-Ascorbate protects against methamphetamine-induced neurotoxicity of cortical cells via inhibiting oxidative stress, autophagy, and apoptosis
    • CrossRef] [PubMed]
    • Huang, Y.N.; Yang, L.Y.; Wang, J.Y.; Lai, C.C.; Chiu, C.T. L-Ascorbate protects against methamphetamine-induced neurotoxicity of cortical cells via inhibiting oxidative stress, autophagy, and apoptosis. Mol. Neurobiol. 2016. [CrossRef] [PubMed]
    • (2016) Mol. Neurobiol
    • Huang, Y.N.1    Yang, L.Y.2    Wang, J.Y.3    Lai, C.C.4    Chiu, C.T.5
  • 142
    • 84975114000 scopus 로고    scopus 로고
    • Sadeghi, A. Protective effects of ascorbic acid and garlic extract against lead-induced apoptosis in developing rat hippocampus
    • CrossRef] [PubMed]
    • Ebrahimzadeh-Bideskan, A.R.; Hami, J.; Alipour, F.; Haghir, H.; Fazel, A.R.; Sadeghi, A. Protective effects of ascorbic acid and garlic extract against lead-induced apoptosis in developing rat hippocampus. Metab. Brain Dis. 2016. [CrossRef] [PubMed]
    • (2016) Metab. Brain Dis
    • Ebrahimzadeh-Bideskan, A.R.1    Hami, J.2    Alipour, F.3    Haghir, H.4    Fazel, A.R.5
  • 143
    • 83155182360 scopus 로고    scopus 로고
    • Association between vitamin D and diabetic neuropathy in a nationally representative sample: Results from 2001 to 2004 nhanes
    • CrossRef] [PubMed]
    • Soderstrom, L.H.; Johnson, S.P.; Diaz, V.A.; Mainous, A.G. Association between vitamin D and diabetic neuropathy in a nationally representative sample: Results from 2001 to 2004 nhanes. Diabet. Med. 2012, 29, 50-55. [CrossRef] [PubMed]
    • (2012) Diabet. Med , vol.29 , pp. 50-55
    • Soderstrom, L.H.1    Johnson, S.P.2    Diaz, V.A.3    Mainous, A.G.4
  • 144
    • 42449146938 scopus 로고    scopus 로고
    • Vitamin D as an analgesic for patients with type 2 diabetes and neuropathic pain
    • CrossRef] [PubMed]
    • Lee, P.; Chen, R. Vitamin D as an analgesic for patients with type 2 diabetes and neuropathic pain. Arch. Int. Med. 2008, 168, 771-772. [CrossRef] [PubMed]
    • (2008) Arch. Int. Med. , vol.168 , pp. 771-772
    • Lee, P.1    Chen, R.2
  • 145
    • 0025315455 scopus 로고
    • Antioxidant activity, biokinetics, and bioavailability
    • CrossRef] [PubMed]
    • Burton, G.W.; Traber, M.G. Vitamin E: Antioxidant activity, biokinetics, and bioavailability. Annu. Rev. Nutr. 1990, 10, 357-382. [CrossRef] [PubMed]
    • (1990) Annu. Rev. Nutr , vol.10 , pp. 357-382
    • Burton, G.W.1    Traber, M.G.2    Vitamin, E.3
  • 146
    • 48749127716 scopus 로고    scopus 로고
    • Protective effect of stobadine on ncv in streptozotocin-diabetic rats: Augmentation by vitamin
    • [PubMed]
    • Skalska, S.; Kyselova, Z.; Gajdosikova, A.; Karasu, C.; Stefek, M.; Stolc, S. Protective effect of stobadine on ncv in streptozotocin-diabetic rats: Augmentation by vitamin E. Gen. Physiol. Biophys. 2008, 27, 106-114. [PubMed]
    • (2008) E. Gen. Physiol. Biophys , vol.27 , pp. 106-114
    • Skalska, S.1    Kyselova, Z.2    Gajdosikova, A.3    Karasu, C.4    Stefek, M.5    Stolc, S.6
  • 147
    • 0033020869 scopus 로고    scopus 로고
    • High rat food vitamin E content improves nerve function in streptozotocin-diabetic rats
    • CrossRef]
    • Van Dam, P.S.; Bravenboer, B.; van Asbeck, B.S.; Marx, J.J.; Gispen, W.H. High rat food vitamin E content improves nerve function in streptozotocin-diabetic rats. Eur. J. Pharmacol. 1999, 376, 217-222. [CrossRef]
    • (1999) Eur. J. Pharmacol , vol.376 , pp. 217-222
    • Van Dam, P.S.1    Bravenboer, B.2    Van Asbeck, B.S.3    Marx, J.J.4    Gispen, W.H.5
  • 148
    • 84995595667 scopus 로고    scopus 로고
    • Treatment of diabetes mellitus-associated neuropathy with vitamin E and eve primrose
    • CrossRef] [PubMed]
    • Ogbera, A.O.; Ezeobi, E.; Unachukwu, C.; Oshinaike, O. Treatment of diabetes mellitus-associated neuropathy with vitamin E and eve primrose. Indian J. Endocrinol. Metab. 2014, 18, 846-849. [CrossRef] [PubMed]
    • (2014) Indian J. Endocrinol. Metab. , vol.18 , pp. 846-849
    • Ogbera, A.O.1    Ezeobi, E.2    Unachukwu, C.3    Oshinaike, O.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.