Growth-promoting effects of quercetin on peripheral nerves in rats

International Journal of Artificial Organs

Volumn 34, Issue 11, 2011, Pages 1095-1105

  Wang, Walter ^a   Huang, Chih Yang ^a,b   Tsai, Fuu Jen ^a   Tsai, Chin Chuan ^c,d   Yao, Chun Hsu ^a   Chen, Yueh Sheng ^a  

^a CHINA MEDICAL UNIVERSITY   (Taiwan)

^b ASIA UNIVERSITY   (Taiwan)

^c I SHOU UNIVERSITY   (Taiwan)

^d E DA HOSPITAL   (Taiwan)

Author keywords

Peripheral nerve regeneration; Quercetin; Silicone rubber

Indexed keywords

ELECTROPHYSIOLOGY; NEURONS; PHENOLS; RUBBER; SILICONES;

ACTION-POTENTIALS; FLAVONOID; GROWTH-PROMOTING EFFECTS; IN-VITRO; MUSCLE ACTION; PERIPHERAL NERVE REGENERATION; PERIPHERAL NERVES; QUERCETIN; VITRO AND IN VIVO; VITRO STUDIES;

FLAVONOIDS;

QUERCETIN; SILICON;

ANIMAL CELL; ARTICLE; CELL CULTURE; CELL SURVIVAL; CONTROLLED STUDY; DRUG EFFECT; IN VITRO STUDY; MORPHOMETRICS; MUSCLE ACTION POTENTIAL; NERVE REGENERATION; NONHUMAN; RAT; SCHWANN CELL; SCIATIC NERVE;

EID: 84055207546     PISSN: 03913988     EISSN: None     Source Type: Journal    
DOI: 10.5301/ijao.5000064     Document Type: Article

References (43)

1. Steed MB. Peripheral nerve response to injury. Atlas Oral Maxillofac Surg Clin North Am. 2011;19:1-13. Medline. doi:10.1016/j.cxom.2010.11.001
2. Haastert K, Joswig H, Jaschke KA, Samii M, Grothe C. Nerve repair by end-to-side nerve coaptation: histologic and morphometric evaluation of axonal origin in a rat sciatic nerve model. Neurosurgery. 2010;66:567-576. discussion 576-577. Medline. doi:10.1227/01. NEU.0000365768.78251.8C
3. Kato H, Minami A, Kobayashi M, Takahara M, Ogino T. Functional results of low median and ulnar nerve repair with intraneural fascicular dissection and electrical fascicular orientation. J Hand Surg Am. 1998;23:471-482. Medline. doi:10.1016/S0363-5023(05)80465-4
4. Wolford LM, Rodrigues DB. Autogenous grafts/allografts/conduits for bridging peripheral trigeminal nerve gaps. Atlas Oral Maxillofac Surg Clin North Am. 2011;19:91-107. Medline. doi:10.1016/j.cxom.2010.11.008
5. Bekler HI, Rosenwasser MP, Akilina Y, Bulut G. The use of an absorbable collagen cover (NeuraWrap) improves patency of interpositional vein grafts. Acta Orthop Traumatol Turc. 2010;44:157-161. Medline. doi:10.3944/ AOTT.2010.2298
6. Yeh CC, Lin YC, Tsai FJ, Huang CY, Yao CH, Chen YS. Timing of applying electrical stimulation is an important factor deciding the success rate and maturity of regenerating rat sciatic nerves. Neurorehabil Neural Repair. 2010;24:730-735. Medline. doi:10.1177/1545968310376758
7. Chen CT, Lin JG, Lu TW, et al. Earthworm extracts facilitate PC12 cell differentiation and promote axonal sprouting in peripheral nerve injury. Am J Chin Med. 2010;38:547-560. Medline. doi:10.1142/S0192415X10008044
8. Lu MC, Yao CH, Wang SH, Lai YL, Tsai CC, Chen YS. Effect of Astragalus membranaceus in rats on peripheral nerve regeneration: in vitro and in vivo studies. J Trauma. 2010;68:434-440. Medline. doi:10.1097/ TA.0b013e31819adb38
9. Chang JY, Ho TY, Lee HC, et al. Highly permeable genip-in-cross-linked gelatin conduits enhance peripheral nerve regeneration. Artif Organs. 2009;33:1075-1085. Medline. doi:10.1111/j.1525-1594.2009.00818.x
10. Lu MC, Tsai CC, Chen SC, Tsai FJ, Yao CH, Chen YS. Use of electrical stimulation at different current levels to promote recovery after peripheral nerve injury in rats. J Trauma. 2009;67:1066-1072. Medline. doi:10.1097/ TA.0b013e318182351a
11. Huang KS, Huang CY, Lin JG, et al. Effect of crude extraction of Paeoniae alba Radix on peripheral nerve regeneration: in-vitro and in-vivo studies. Evid-based Complement Altern Med. 2011. Medline. doi: 10.1093/ ecam/nep115".
12. Wang Y, Ho CT. Polyphenolic chemistry of tea and coffee: a century of progress. J Agric Food Chem. 2009;57:8109-8114. Medline. doi:10.1021/jf804025c
13. Araujo JR, Goncalves P, Martel F. Chemopreventive effect of dietary polyphenols in colorectal cancer cell lines. Nutr Res. 2011;31:77-87. Medline. doi:10.1016/j. nutres.2011.01.006
14. Perez-Vizcaino F, Duarte J. Flavonols and cardiovascular disease. Mol Aspects Med. 2010;31:478-494. Medline. doi:10.1016/j.mam.2010.09.002
15. Chirumbolo S. The role of quercetin, flavonols and flavones in modulating inflammatory cell function. Inflamm Allergy Drug Targets. 2010;9:263-285.
16. Ossola B, Kaariainen TM, Mannisto PT. The multiple faces of quercetin in neuroprotection. Expert Opin Drug Saf.2009;8:397-409. Medline. doi:10.1517/14740330903026944
17. Chang YF, Hsu YC, Hung HF, et al. Quercetin induces oxidative stress and potentiates the apoptotic action of 2-methoxyestradiol in human hepatoma cells. Nutr Cancer. 2009;61:735-745. Medline. doi:10.1080/01635580902825571
18. Matsuo M, Sasaki N, Saga K, Kaneko T. Cytotoxicity of flavonoids toward cultured normal human cells. Biol Pharm Bull. 2005;28:253-259. Medline. doi:10.1248/ bpb.28.253
19. Nakata N, Kato H, Kogure K. Inhibition of ischaemic tolerance in the gerbil hippocampus by quercetin and anti-heat shock protein-70 antibody. Neuroreport. 1993;4:695-698. Medline. doi:10.1097/00001756-199306000-00023
20. De Vries GH, Boullerne AI. Glial cell lines: an overview. Neurochem Res. 2010;35:1978-2000. Medline. doi:10.1007/s11064-010-0318-9
21. Siemionow M, Bozkurt M, Zor F. Regeneration and repair of peripheral nerves with different biomaterials [review]. Microsurgery. 2010;30:574-588. Medline. doi:10.1002/ micr.20799
22. Zhang M, Yannas IV. Peripheral nerve regeneration. Adv Biochem Eng Biotechnol. 2005;94:67-89.
23. Chung TW, Yang MC, Tseng CC, et al. Promoting regeneration of peripheral nerves in-vivo using new PCL-NGF/Tirofiban nerve conduits. Biomaterials. 2011;32:734-743. Medline. doi:10.1016/j.biomaterials.2010.09.023
24. Vogelin E, Baker JM, Gates J, Dixit V, Constantinescu MA, Jones NF. Effects of local continuous release of brain derived neurotrophic factor (BDNF) on peripheral nerve regeneration in a rat model. Exp Neurol. 2006;199:348-353. Medline. doi:10.1016/j.expneurol.2005.12.029
25. Yoshii S, Shima M, Oka M, Taniguchi A, Taki Y, Akagi M. Nerve regeneration along collagen filament and the presence of distal nerve stump. Neurol Res. 2004;26:145-150. Medline. doi:10.1179/016164104225013770
26. Woolley AL, Hollowell JP, Rich KM. First place: Resident Basic Science Award 1990. Fibronectin-laminin combination enhances peripheral nerve regeneration across long gaps. Otolaryngol Head Neck Surg. 1990;103:509-518.
27. Lin LZ, Harnly JM. Phenolic component profiles of mustard greens, yu choy, and 15 other brassica vegetables. J Agric Food Chem. 2010;58:6850-6857. Medline. doi:10.1021/jf1004786
28. Azuma K, Ippoushi K, Terao J. Evaluation of tolerable levels of dietary quercetin for exerting its antioxidative effect in high cholesterol-fed rats. Food Chem Toxicol. 2010;48:1117-1122. Medline. doi:10.1016/j. fct.2010.02.005
29. Lin HY, Kuo YH, Lin YL, Chiang W. Antioxidative effect and active components from leaves of Lotus (Nelum-bo nucifera). J Agric Food Chem. 2009;57:6623-6629. Medline. doi:10.1021/jf900950z
30. Wang SY, Chen CT, Sciarappa W, Wang CY, Camp MJ. Fruit quality, antioxidant capacity, and flavonoid content of organically and conventionally grown blueberries. J Agric Food Chem. 2008;56:5788-5794. Medline. doi:10.1021/jf703775r
31. Terao J. Dietary flavonoids as antioxidants. Forum Nutr. 2009;61:87-94. Medline. doi:10.1159/000212741
32. Heo HJ, Lee CY. Protective effects of quercetin and vitamin C against oxidative stress-induced neurodegeneration. J Agric Food Chem. 2004;52:7514-7517. Medline. doi:10.1021/jf049243r
33. Ao Q, Fung CK, Tsui AY, et al. The regeneration of transected sciatic nerves of adult rats using chitosan nerve conduits seeded with bone marrow stromal cell-derived Schwann cells. Biomaterials. 2011;32:787-796. Medline. doi:10.1016/j.biomaterials.2010.09.046
34. Ladak A, Olson J, Tredget EE, Gordon T. Differentiation of mesenchymal stem cells to support peripheral nerve regeneration in a rat model. Exp Neurol. 2011;228:242-252. Medline. doi:10.1016/j.expneurol.2011.01.013
35. Werdin F, Grussinger H, Jaminet P, et al. An improved electrophysiological method to study peripheral nerve regeneration in rats. J Neurosci Methods. 2009;182:71-77. Medline. doi:10.1016/j.jneumeth.2009.05.017
36. Lago N, Rodriguez FJ, Guzman MS, Jaramillo J, Navarro X. Effects of motor and sensory nerve transplants on amount and specificity of sciatic nerve regeneration. J Neurosci Res. 2007;85:2800-2812. Medline. doi:10.1002/jnr.21286
37. Spencer JP. The impact of fruit flavonoids on memory and cognition. Br J Nutr. 2010;104(Suppl 3):S40-S47. Medline. doi:10.1017/S0007114510003934
38. Joseph JA, Shukitt-Hale B, Lau FC. Fruit polyphenols and their effects on neuronal signaling and behavior in senescence. Ann N Y Acad Sci. 2007;1100:470-485. Medline. doi:10.1196/annals.1395.052
39. Sasaki M, Nakamura H, Tsuchiya S, et al. Quercetin-induced PC12 cell death accompanied by caspase-mediated DNA fragmentation. Biol Pharm Bull. 2007;30:682-686. Medline. doi:10.1248/bpb.30.682
40. Manach C, Williamson G, Morand C, Scalbert A, Remesy C. Bioavailability and bioefficacy of polyphenols in humans: Part I: review of 97 bioavailability studies. Am J Clin Nutr. 2005;81:230S-242S.
41. Gallo G, Lefcort FB, Letourneau PC. The trkA receptor mediates growth cone turning toward a localized source of nerve growth factor. J Neurosci. 1997;17:5445-5454.
42. Boyd JG, Gordon T. A dose-dependent facilitation and inhibition of peripheral nerve regeneration by brain-derived neurotrophic factor. Eur J Neurosci. 2002;15:613-626. Medline. doi:10.1046/j.1460-9568.2002.01891.x
43. Hirata A, Masaki T, Motoyoshi K, Kamakura K. Intrathecal administration of nerve growth factor delays GAP 43 expression and early phase regeneration of adult rat peripheral nerve. Brain Res. 2002;944:146-156. Medline. doi:10.1016/S0006-8993(02)02739-7