Ameliorative effect of diosmin, a citrus flavonoid against streptozotocin-nicotinamide generated oxidative stress induced diabetic rats

Chemico-Biological Interactions

Volumn 195, Issue 1, 2012, Pages 43-51

  Srinivasan, Subramani ^a   Pari, Leelavinothan ^a  

^a ANNAMALAI UNIVERSITY   (India)

Author keywords

Antioxidants; Diosmin; Lipid peroxidation; Streptozotocin

Indexed keywords

ALPHA TOCOPHEROL; ASCORBIC ACID; CATALASE; DIOSMIN; GLUCOSE; GLUTATHIONE; GLUTATHIONE PEROXIDASE; GLUTATHIONE TRANSFERASE; INSULIN; LIPID; NICOTINAMIDE; STREPTOZOCIN; SUPEROXIDE DISMUTASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIDIABETIC ACTIVITY; ARTICLE; BIOCHEMISTRY; CONTROLLED STUDY; DRUG MECHANISM; ENZYME ACTIVITY; GLUCOSE BLOOD LEVEL; HISTOPATHOLOGY; INSULIN BLOOD LEVEL; KIDNEY PARENCHYMA; LIPID PEROXIDATION; LIVER; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; OXIDATIVE STRESS; RAT;

ADMINISTRATION, ORAL; ANIMALS; ASCORBIC ACID; CATALASE; DIABETES MELLITUS, EXPERIMENTAL; DIOSMIN; GLUTATHIONE; GLUTATHIONE PEROXIDASE; GLUTATHIONE TRANSFERASE; HYPOGLYCEMIC AGENTS; KIDNEY; LIPID PEROXIDATION; LIVER; MALE; NIACINAMIDE; OXIDATIVE STRESS; RATS; RATS, WISTAR; STREPTOZOCIN; SUPEROXIDE DISMUTASE; VITAMIN E;

CITRUS; RATTUS;

EID: 82055194290     PISSN: 00092797     EISSN: 18727786     Source Type: Journal    
DOI: 10.1016/j.cbi.2011.10.003     Document Type: Article

References (73)

1. G. Saravanan, and P. Ponmurugan Ameliorative potential of S-allyl cysteine on oxidative stress in STZ induced diabetic rats Chem. Biol. Interact. 189 2011 100 106
2. A.K. Tiwari, and J. Madhusudana Rao Diabetes mellitus and multiple therapeutic approaches of phytochemicals: present status and future prospects Curr Sci. 83 2002 30 38 (Pubitemid 135693173)
3. V.M. Bhor, N. Raghuram, and S. Sivakami Oxidative damage and altered antioxidant enzymes activities in the intestine of streptozotocin induced diabetic rats Int. J. Biochem. Cell. Biol. 36 2004 89 97 (Pubitemid 37338475)
4. T. Peerapatdit, A. Likidlilid, N. Patchanans, and A. Somkasetrin Antioxidant status and lipid peroxidation end products in patients of type 1 diabetes mellitus Med. Assoc. Thai. 89 2006 141 146
5. M.M. Sklavos, S. Bertera, H.M. Tse, R. Bottino, J. He, J.N. Beilke, M.G. Coulombe, R.G. Gill, J.D. Crapo, M. Trucco, and J.D. Piganelli Redox modulation protects islets from transplant-related injury Diabetes 59 2010 1731 1738
6. C.S. Wilcox, and D. Gutterman Focus on oxidative stress in the cardiovascular and renal systems Am. J. Physiol. Heart Circ. Physiol. 288 2005 3 6
7. M.J. Kim, G.R. Ryu, J.S. Chung, S.S. Sim, D.J. Min Dos Rhie, S.H. Yoon, S.J. Hahn, M.S. Kim, and Y.M. Jo Protective effect of epicatechin against the toxic effects of STZ on rat pancreatic islets: in vivo and in vitro Pancreas 26 2003 292 299 (Pubitemid 36384163)
8. S. Lenzen The mechanisms of alloxan- and streptozotocin-induced diabetes Diabetologia 51 2008 216 226
9. I.T. Nizamutdinova, Y.C. Jin, J.I. Chung, S.C. Shin, S.J. Lee, H.G. Seo, J.H. Lee, K.C. Chang, and H.J. Kim The anti-diabetic effect of anthocyanins in streptozotocin-induced diabetic rats through glucose transporter 4 regulation and prevention of insulin resistance and pancreatic apoptosis Mol. Nutr. Food Res. 53 2009 1419 1429
10. A. Likidlilid, N. Patchanans, T. Peerapatdit, and C. Sriratanasathavorn Lipid peroxidation and antioxidant enzyme activities in erythrocytes of type 2 diabetic patients J. Med. Assoc. Thai. 93 2010 682 693
11. S.O. Adewole, and J.A. Ojewole Protective effects of Annona muricata Linn. (Annonaceae) leaf aqueous extract on serum lipid profiles and oxidative stress in hepatocytes of streptozotocin-treated diabetic rats Afr. J. Tradit. Complement. Altern. Med. 6 2008 30 41
12. S.B. Budin, F. Othman, S.R. Louis, M.A. Bakar, S. Das, and J. Mohamed The effects of palm oil tocotrienol-rich fraction supplementation on biochemical parameters, oxidative stress and the vascular wall of streptozotocin-induced diabetic rats Clinics (Sao Paulo) 64 2009 235 244
13. N. Rangkadilok, S. Sitthimonchai, L. Worasuttayangkurn, C. Mahidol, M. Ruchirawat, and J. Satayavivad Evaluation of free radical scavenging and antityrosinase activities of standardized longan fruit extract Food Chem. Toxicol. 45 2007 328 336 (Pubitemid 44872916)
14. Y. Srivastava, H.V. Bhat, Y. Verma, and K.V. Enkaidh Antidiabetic and adaptogenic properties of Momordica charantia extract: an experimental and clinical evaluation Phytotherapy. Res. 7 1993 285 288
15. E. Mary, L. Waltner, L. Xiaohui, K.L. Wang Brian, K.H. Robert, M. Nawano, and D.K. Granner Epigallocatechin gallate, a constituent of green tea, represses hepatic glucose production J. Biol. Chem. 277 2002 34933 34940
16. J.F. Alvarez, A. Barbera, B. Nadal, S. Barcelo-Batllori, S. Piquer, M. Claret, J.J. Guinovart, N. Guinovart, and R. Gomis Stable and functional regeneration of pancreatic beta-cell population in n-STZ rats treated with tungstate Diabetologia 47 2004 470 477 (Pubitemid 38491243)
17. M.A. Campanero, M. Escolar, E. Perez Garcia-Quetglas, B. Sadaba, and J.R. Azanza Simultaneous determination of diosmin and diosmetin in human plasma by ion trap liquid chromatography-atmospheric pressure chemical ionization tandem mass spectrometry J. Pharm. Biomed. Anal. 51 2010 875 881
18. L. Le Marchand, S.P. Murphy, J.H. Hankin, L.R. Wilkens, and L.N. Kolonel Intake of flavonoids and lung cancer J. Nat. Cancer Inst. 92 2000 154 160 (Pubitemid 30089873)
19. Z.V. Maksimovic, M. Maksimovic, D. Jadranin, I. Kuzmanovic, and O. Andonovic Medicamentous treatment of chronic venous insufficiency using semisynthetic diosmin a prospective study Acta Chir. Iugosl. 55 2008 53 59
20. M.R. Cesarone, G. Belcaro, L. Pellegrini, A. Ledda, G. Vinciguerra, A. Ricci, A. Di Renzo, I. Ruffini, G. Gizzi, E. Ippolito, F. Fano, M. Dugall, G. Acerbi, U. Cornelli, M. Hosoi, and M. Cacchio Venoruton vs Daflon: evaluation of effects on quality of life in chronic venous insufficiency Angiology 57 2006 33 339
21. A. Unlu, N. Sucu, L. Tamer, B. Coskun, G. Yucebilgic, B. Ercan, A. Gul, M. Dikmengil, and U. Atik Effects of Daflon on oxidative stress induced by hindlimb ischemia/reperfusion Pharmacol. Res. 48 2003 11
22. L. Pari, and S. Srinivasan Antihyperglycemic effect of diosmin on hepatic key enzymes of carbohydrate metabolism in streptozotocin-nicotinamide-induced diabetic rats Biomed. Pharmacother. 64 2010 477 481
23. L. Pari, and S. Srinivasan Preventive effect of diosmin, a bioflavonoid, on glycoprotein changes in streptozotocin-nicotinamide-induced type 2 diabetic rats In. J. Pharm. Sci. Res. 10 2010 89 95
24. P. Masiello, C. Broca, R. Gross, M. Roye, M. Manteghetti, D. Hillaire-Buys, M. Novelli, and G. Ribes Experimental NIDDM: development of a new model in adult rats administered streptozotocin and nicotinamide Diabetes 47 1998 224 229 (Pubitemid 28079978)
25. J. Folch, M. Lees, and S.G.H. Solane A simple method for isolation and purification of total lipids from animal tissues J. Biol. Chem. 26 1957 497 509
26. P. Trinder Determination of glucose in blood using glucose oxidase with analternative oxygen acceptor Ann. Clin. Biochem. 6 1969 24
27. C.G. Fraga, B.E. Leibouitz, and A.L. Toppel Lipid peroxidation measured as TBARS in tissue slices: characterization and comparison with homogenates and microsomes J. Free Rad. Biol. Med. 4 1988 155 161 (Pubitemid 18052530)
28. Z.Y. Jiang, J.V. Hunt, and S.P. Wolff Ferrous ion oxidation in the presence of xylenol orange for detection of lipid hydroperoxide in low density lipoprotein Anal. Biochem. 202 1992 384 389
29. A.K. Sinha Colorimetric assay of catalase Anal. Biochem. 47 1972 389 394
30. R. Kakkar, S.V. Mantha, J. Radhi, K. Prasad, and J. Kalra Increased oxidative stress in rat liver and pancreas during progression of streptozotocin induced diabetes Clin. Sci. 94 1998 623 632 (Pubitemid 28269062)
31. J.T. Rotruck, A.L. Pope, and H.E. Ganther Selenium biochemical role as a component of glutathione peroxidase purification assay Science 179 1973 588 590
32. W.H. Habig, M.J. Pabst, and W.B. Jakpoby Glutathione transferase, a first enzymatic step in mercapturic acid formation J. Biol. Chem. 249 1974 7130 7139
33. H.D. Horn, and F.H. Burns Assay of glutathione reductase activity H.V. Bergemeyer, Methods of Enzymatic Analysis 1978 Academic Press New York, USA 142 146
34. E. Beutler, and B.M. Kelly The effect of sodium nitrate on RBC glutathione Experienta 19 1963 96 97
35. M. Aseni, J. Sastre, F.V. Pallardo, A. Lloret, M. Lehner, and J. Garciade-la Asuncion Ratio of reduced to oxidized glutathione as indicator of oxidative stress status and DNA damage Methods Enzymol. 299 1999 267 276 (Pubitemid 28483899)
36. S.T. Omaye, T.D. Turbull, H.C. Sauberlich, Selected method for the determination of ascorbic acid in animal cells, tissues and fluids. In: D.B. McCormic, D.L. Wright (eds.), Methods Enzymology, vol. 62. Academic Press, New York, USA, 1979, pp. 3-11.
37. H. Baker, O. Frank, B. Angelis, and S. Feingold Plasma tocopherol in man at various times after ingesting free or acetylated tocopherol Nutr. Report Intern. 21 1951 531 536
38. O.H. Lowry, N.J. Rosenbrough, A.L. Farr, and R.J. Randall Protein measurement with Folins Phenol reagent J. Biol. Chem. 193 1951 265 278
39. B.D. Duncan Multiple ranges tests for correlated and heteroscedastic means Biometrics 13 1957 359 364
40. J. Thulesen, C. Orskov, J.J. Holst, and S.S. Poulsen Short-term insulin treatment prevents the diabetogenic action of streptozotocin in rats Endocrinology 138 1997 62 68 (Pubitemid 27009406)
41. K. Shima, M. Zhu, and M. Kuwajima A role of nicotinamide-induced increase in pancreatic beta-cell mass on blood glucose control after discontinuation of the treatment in partially pancreatectomized OLETF rats Diabetes Res. Clin. Pract. 41 1998 1 8 (Pubitemid 28394278)
42. E. Tripoli, M. La Guardia, S. Giammanco, D. Di Majo, and M. Giammanco Citrus flavonoids: molecular structure, biological activity and nutritional properties, a review Food Chem. 104 2007 466 479 (Pubitemid 46661050)
43. O. Coskun, M. Kanter, A. Korkmaz, and S. Oter Quercetin, a flavonoid antioxidant, prevents and protects streptozotocin-induced oxidative stress and β-cell damage in rat pancreas Food Chem. 108 2008 965 972
44. D. Giugliano, A. Ceriello, and G. Paolisso Oxidative stress and diabetic vascular complications Diabetes Care 19 1996 257 267 (Pubitemid 26070354)
45. K. Karthikesan, L. Pari, and P. Menon Protective effect of tetrahydrocurcumin and chlorogenic acid against streptozotocin-nicotinamide generated oxidative stress induced diabetes J. Funct. Foods. 2 2010 134 142
46. A.C. Maritim, R.A. Sandres, and J.B. Watkins Diabetes, oxidative stress, and antioxidants: a review J. Biochem. Mol. Toxicol. 17 2003 24 39
47. K. Parveen, M.R. Khan, M. Mujeeb, and W.A. Siddiqui Protective effects of Pycnogenol on hyperglycemia-induced oxidative damage in the liver of type 2 diabetic rats Chem. Biol. Interact. 186 2010 219 227
48. T. Atli, K. Keven, A. Avci, S. Kutlay, N. Turkcapar, M. Varli, S. Aras, E. Ertug, and O. Canbolat Oxidative stress and antioxidant status in elderly diabetes mellitus and glucose intolerance patients Arch. Gerontol. Geriatr. 39 2004 269 275 (Pubitemid 39277486)
49. P. Arivazhagam, T. Thilagavathy, and C. Pannerselvam Antioxidant lipoate and tissue antioxidants in aged rats J. Nutr. Biochem. 11 2000 122 127
50. P. Murugan, and L. Pari Antioxidant effect of tetrahydrocurcumin in streptozotocin-nicotinamide induced diabetic rats Life Sci. 79 2006 1720 1728 (Pubitemid 44374550)
51. E.Y. Sozmen, B. Sozmen, Y. Delen, and T. Onat Catalase/superoxide dismutase (SOD) and catalase/paraoxonase (PON) ratios may implicate poor glycemic control Arch. Med. Res. 32 2001 283 287 (Pubitemid 32611640)
52. C. Sankaranarayanan, and L. Pari Thymoquinone ameliorates chemical induced oxidative stress and β-cell damage in experimental hyperglycemic rats Chem. Biol. Interact. 190 2011 148 154
53. N.T. Friesen, A. SBuchau, P. Schott-Ohly, and A. Lggssiar Generation of hydrogen peroxide and failure of antioxidative responses in pancreatic islets of male C57BL/6 mice are associated with diabetes induced by multiple low doses of streptozotocin Diabetologia 47 2004 676 685 (Pubitemid 38658370)
54. T.M. Danyelle, and T.D. Kenneth The role of glutathione-S-transferase in anticancer drug resistance Drug Res. 22 2003 7369 7375
55. C.C. Winterbourn Concerted antioxidant activity of glutathione and superoxide dismutase L. Packer, J. Fuchs, Biothiols in Health and Disease 1995 Marcel Dekker Inc. New York 117 134
56. S.A. Ewis, and M.S. Abdel-Rahman Effect of metformin on glutathione and magnesium in normal and streptozotocin-induced diabetic rats J. Appl. Toxicol. 15 1995 387 390
57. J. Haung, and M.A. Philbert Cellular responses of cultured cerebellar astrocytes to ethacrynic acid-induced perturbation of subcellular glutathione homeostasis Brain Res. 711 1996 184 192 (Pubitemid 26080241)
58. N.H. Ugochukwu, N.D. Bagayoko, and M.E. Antwi The effects of dietary caloric restriction on antioxidant status and lipid peroxidation in mild and severe streptozotocin-induced diabetic rats Clin. Chim. Acta 348 2004 121 129 (Pubitemid 39209010)
59. Y. Manuel, B. Keenoy, J. Vertommen, and I. De Leeuw The effect of flavonoid treatment on the glycation and antioxidant status in type 1 diabetic patients Diabetes Nutr. Metab. 12 1999 256 263
60. C.A. Rice-Evans, N.J. Miller, and G. Paganga Structure-antioxidant activity relationships of flavonoids and phenolic acids Free Rad. Biol. Med. 20 1996 933 956 (Pubitemid 26157509)
61. N.N. Ulusu, M. Sahilli, A. Avci, O. Canbolat, G. Ozansoy, N. Ari, M. Bali, M. Stefek, S. Stolc, A. Gajdosik, and C. Karasu Pentose phosphate pathway, glutathione-dependent enzymes and antioxidant defence during oxidative stress in diabetic rodent brain and peripheral organs effects of stobadine and vitamin E Neurochem. Res. 28 2003 815 823 (Pubitemid 36438397)
62. S.K. Jain Glutathione and glucose-6-phophate dehydrogenase deficiency can increase protein glycation Free Rad. Biol. Med. 24 1998 197 201 (Pubitemid 28006453)
63. R. Masella, R. Vari, M. D'Archivio, R. Benedetto, P. Matarrese, W. Malorni, B. Scazzocchio, and C. Giovannini Extra virgin olive oil biophenols inhibit cell-mediated oxidation of LDL by increasing the mRNA transcription of glutathione-related enzymes J. Nutr. 134 2004 785 791 (Pubitemid 38456244)
64. D.M. Townsend, K.D. Tew, and H. Tapiero The importance of glutathione in human disease Biomed. Pharmacother. 57 2003 145 155 (Pubitemid 36740460)
65. L.D. DeLeve, X. Wang, J.F. Kuhlenkamp, and N. Kaplowitz Toxicity of azathioprine and monocrotaline in murine sinusoidal endothelial cells and hepatocytes: the role of glutathione and relevance to hepatic venoocclusive disease Hepatology 23 1996 589 599 (Pubitemid 26087175)
66. S.M. Rizk, and N.A. Sabri Evaluation of clinical activity and safety of Daflon 500 mg in type 2 diabetic female patients Saudi Pharma. J. 16 2009 199 207
67. M. Reid, and F. Jahoor Glutathione in disease Curr. Opin. Clin. Nutr. Metab. Care 4 2001 65 71 (Pubitemid 34754482)
68. M.A. El-Missirya, and A.M. El Gindy Amelioration of alloxan induced diabetes mellitus and oxidative stress in rats by oil of eruca sativa seeds Ann. Nutr. Metab. 44 2000 97 100
69. S.S. Chung, E.C. Ho, K.S. Lam, and S.K. Chung Contribution of polyol pathway to diabetes-induced oxidative stress J. Am. Soc. Nephrol. 14 2003 233 236
70. Y. Ozkan, O. Yilmaz, A.I. Oztürk, and Y. Ersan Effects of triple antioxidant combination (vitamin E, vitamin C and alpha-lipoic acid) with insulin on lipid and cholesterol levels and fatty acid composition of brain tissue in experimental diabetic and non-diabetic rats Cell Biol. Int. 29 2005 754 760 (Pubitemid 41558166)
71. V. Tiwari, A. Kuhad, M. Bishnoi, and K. Chopra Chronic treatment with tocotrienol, an isoform of vitamin E, prevents intracerebroventricular streptozotocin-induced cognitive impairment and oxidative-nitrosative stress in rats Pharmacol. Biochem. Behav. 93 2009 183 189
72. V. Opoka-Winiarska Impaired metabolism and effects of vitamin C supplementation on diabetes Diabetol. Pol. 7 2001 208 211
73. V.R. Punithavathi, R. Anuthama, and P.S. Prince Combined treatment with naringin and vitamin C ameliorates streptozotocin-induced diabetes in male Wistar rats J. Appl. Toxicol. 28 2008 806 813