Association between vitaminD and diabetic neuropathy in a nationally representative sample: Results from 2001-2004 NHANES

Diabetic Medicine

Volumn 29, Issue 1, 2012, Pages 50-55

  Soderstrom, L H ^a   Johnson, S P ^a   Diaz, V A ^a   Mainous, A G ^a  

^a MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

Author keywords

Diabetes mellitus; Peripheral neuropathy; Vitamin D

Indexed keywords

VITAMIN D;

ADULT; AGED; ARTICLE; CLINICAL FEATURE; DIABETIC NEUROPATHY; ETHNICITY; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; PARESTHESIA; QUESTIONNAIRE; SKIN TINGLING; VITAMIN BLOOD LEVEL; VITAMIN D DEFICIENCY; AFRICAN AMERICAN; CAUCASIAN; CROSS-SECTIONAL STUDY; ETHNOLOGY; HISPANIC; MIDDLE AGED; NUTRITION; PREVALENCE; RISK; SELF REPORT; STATISTICAL MODEL; UNITED STATES;

ADULT; AFRICAN AMERICANS; CROSS-SECTIONAL STUDIES; DIABETIC NEUROPATHIES; EUROPEAN CONTINENTAL ANCESTRY GROUP; FEMALE; HISPANIC AMERICANS; HUMANS; LOGISTIC MODELS; MALE; MIDDLE AGED; NUTRITION SURVEYS; ODDS RATIO; PREVALENCE; QUESTIONNAIRES; SELF REPORT; UNITED STATES; VITAMIN D; VITAMIN D DEFICIENCY;

EID: 83155182360     PISSN: 07423071     EISSN: 14645491     Source Type: Journal    
DOI: 10.1111/j.1464-5491.2011.03379.x     Document Type: Article

References (21)

1. Holick MF. VitaminD for health and in chronic kidney disease. Semin Dial 2005; 18: 266-275.
2. Holick MF. Vitamin D deficiency. N Engl J Med 2007; 357: 266-281.
3. Pittas AG, Lau J, Hu F, Dawson-Hughes B. The role of vitaminD and calcium in type2 diabetes: a systematic review and meta-analysis. J Clin Endocrin Metab 2007; 92: 2017-2029.
4. Sugden JA, Davies JI, Witham MD, Morris AD, Struthers AD. Vitamin D improves endothelial function in patients with Type2 diabetes mellitus and low vitaminD levels. Diabet Med 2008; 25: 320-325.
5. Pittas AG, Dawson-Hughes B, Li T, Van Dam RM, Willett WC, Manson JE et al. VitaminD and calcium intake in relation to type2 diabetes in women. Diabetes Care 2006; 29: 650-656.
6. Penckofer S, Kouba J, Wallis DE, Emanuele MA. VitaminD and diabetes: let the sunshine in. Diabetes Educ 2008; 34: 939-944.
7. Danescu LG, Levy S, Levy J. Vitamin D and diabetes mellitus. Endocrine 2009; 35: 11-17.
8. National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health. Diabetic Neuropathies: The Nerve Damage of Diabetes. 2009. Available at Last accessed 11 November 2010.
9. Argoff C, Cole E, Fishbain D, Irving G. Diabetic peripheral neuropathic pain: clinical and quality-of-life issues. Mayo Clin Proc 2006; 81: S3-S11.
10. Garcion E, Wion-Barbot N, Montero-Menei CN, Berger F, Wion D. New clues about vitaminD functions in the nervous system. Trends Endocrinol Metab 2002; 13: 100-105.
11. Riaz S, Malcangio M, Miller M, Tomlinson DR. A VitaminD(3) derivative (CB1093) induces nerve growth factor and prevents neurotrophic deficits in streptozotocin-diabetic rats. Diabetologia 1999; 42: 1308-1313.
12. Lee P, Chen R. VitaminD as an analgesic for patients with type2 diabetes and neuropathic pain. Arch Intern Med 2008; 168: 771-772.
13. Pham H, Armstrong DG, Harvey C, Harkless LB, Giurini JM, Veves A. Screening techniques to identify people at high risk for diabetic foot ulceration: a prospective multicenter trial. Diabetes Care 2000; 23: 606-611.
14. Gregg EW, Sorlie P, Paulose-Ram R, Gu Q, Eberhardt MS, Wolz M et al. Prevalence of lower-extremity disease in the US adult population ≥40years of age with and without diabetes: 1999-2000 National Health and Nutrition Examination Survey. Diabetes Care 2004; 27: 1591-1597.
15. Tesfaye S, Chaturvedi N, Eaton SE, Ward JD, Manes C, Ionescu-Tirgoviste C et al. Vascular risk factors and diabetic neuropathy. N Engl J Med 2005; 352: 341-350.
16. Mitchell BD, Hawthorne VM, Vinik AI. Cigarette smoking and neuropathy in diabetic patients. Diabetes Care 1990; 13: 434-437.
17. Anonymous. Executive summary: standards of medical care in diabetes - 2010. Diabetes Care 2010; 33: S4-S10.
18. Partanen J, Niskanen L, Lehtinen J, Mervaala E, Siitonene O, Uusitupa M. Natural history of peripheral neuropathy in patients with non-insulin-dependent diabetes mellitus. N Engl J Med 1995; 333: 89-94.
19. Feldman EL, McCulloch DK. Treatment of diabetic neuropathy. 2010. Available at Last accessed 11 November 2010.
20. Annweiler C, Schott AM, Rolland Y, Blain H, Herrmann FR, Beauchet O. Dietary intake of vitaminD and cognition in older women: a large population-based study. Neurology 2010; 75: 1810-1816.
21. Llewellyn DJ, Lang IA, Langa KM, Muniz-Terrera G, Phillips CL, Cherubini A et al. VitaminD and risk of cognitive decline in elderly persons. Arch Intern Med 2010; 170: 1135-1141.