Hyperglycemia inhibits retinoic acid-induced activation of Rac1, prevents differentiation of cortical neurons, and causes oxidative stress in a rat model of diabetic pregnancy

Diabetes

Volumn 55, Issue 12, 2006, Pages 3326-3334

  Guleria, Rakeshwar S ^a   Pan, Jing ^a   DiPette, Donald ^a   Singh, Ugra S ^a,b  

^a TEXAS A AND M UNIVERSITY SYSTEM   (United States)

^b Cardiovascular Research Institute   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE 9; GLUTATHIONE; MANGANESE SUPEROXIDE DISMUTASE; MICROTUBULE ASSOCIATED PROTEIN 2; NEUROMODULIN; RAC1 PROTEIN; RETINOIC ACID; TAU PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIOXIDANT ACTIVITY; APOPTOSIS; ARTICLE; BRAIN CELL; BRAIN DEVELOPMENT; CELL ISOLATION; CONTROLLED STUDY; DIABETES MELLITUS; EMBRYO; ENZYME ACTIVATION; ENZYME INHIBITION; FEMALE; HYPERGLYCEMIA; LIPID PEROXIDATION; NERVE CELL DIFFERENTIATION; NERVE FIBER GROWTH; NONHUMAN; OXIDATIVE STRESS; PREGNANCY; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SIGNAL TRANSDUCTION;

ANIMALS; APOPTOSIS; CELL DIFFERENTIATION; CEREBRAL CORTEX; DIABETES MELLITUS, EXPERIMENTAL; FEMALE; HYPERGLYCEMIA; NEURONS; OXIDATIVE STRESS; PREGNANCY; PREGNANCY COMPLICATIONS; RAC1 GTP-BINDING PROTEIN; RATS; RATS, SPRAGUE-DAWLEY; SUPEROXIDE DISMUTASE; TRETINOIN;

EID: 33845546972     PISSN: 00121797     EISSN: 00121797     Source Type: Journal    
DOI: 10.2337/db06-0169     Document Type: Article

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