Rutin ameliorates diabetic neuropathy by lowering plasma glucose and decreasing oxidative stress via Nrf2 signaling pathway in rats

European Journal of Pharmacology

Volumn 771, Issue , 2016, Pages 84-92

  Tian, Ruifeng ^a   Yang, Wenqing ^b   Xue, Qiang ^a   Gao, Liang ^a   Huo, Junli ^a   Ren, Dongqing ^c   Chen, Xiaoyan ^a  

^a FOURTH MILITARY MEDICAL UNIVERSITY   (China)

^b Lanzhou Military Region of PLA ^*  (China)

^c FOURTH MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Diabetic neuropathy; Hydrogen sulfide; Neuroinflammation; Nrf2; Oxidative stress; Rutin

Indexed keywords

ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); ANTIDIABETIC AGENT; CASPASE 3; FUMARIC ACID DIMETHYL ESTER; GLUCOSE; HEME OXYGENASE 1; HYDROGEN SULFIDE; INSULIN; RUTOSIDE; TRANSCRIPTION FACTOR NRF2; CASP3 PROTEIN, RAT; GLUCOSE BLOOD LEVEL;

ADULT; ALLODYNIA; ANIMAL EXPERIMENT; ANTIINFLAMMATORY ACTIVITY; ANTIOXIDANT ACTIVITY; ARTICLE; CONTROLLED STUDY; DIABETIC NEUROPATHY; ENZYME ACTIVITY; GLUCOSE BLOOD LEVEL; HYPERALGESIA; MALE; MECHANICAL HYPERALGESIA; NERVE CONDUCTION VELOCITY; NERVOUS SYSTEM INFLAMMATION; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SCIATIC NERVE; SPINAL GANGLION; THERMAL HYPERALGESIA; UPREGULATION; ANIMAL; BIOSYNTHESIS; BLOOD; DIABETIC NEUROPATHIES; DRUG EFFECTS; GENETICS; METABOLISM; NERVE CONDUCTION; SIGNAL TRANSDUCTION; SPRAGUE DAWLEY RAT;

ANIMALS; BLOOD GLUCOSE; CASPASE 3; DIABETIC NEUROPATHIES; HEME OXYGENASE-1; HYDROGEN SULFIDE; HYPERALGESIA; HYPOGLYCEMIC AGENTS; INSULIN; MALE; NEURAL CONDUCTION; NF-E2-RELATED FACTOR 2; OXIDATIVE STRESS; RATS; RATS, SPRAGUE-DAWLEY; RUTIN; SIGNAL TRANSDUCTION; SODIUM-POTASSIUM-EXCHANGING ATPASE;

EID: 84950136414     PISSN: 00142999     EISSN: 18790712     Source Type: Journal    
DOI: 10.1016/j.ejphar.2015.12.021     Document Type: Article

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