Antioxidants and herbal extracts protect HT-4 neuronal cells against glutamate-induced cytotoxicity

Free Radical Research

Volumn 32, Issue 2, 2000, Pages 115-124

  Kobayashi, Michael S ^a   Han, Derick ^b   Packer, Lester ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

Antioxidant; Ginkgo biloba; Glutathione; Neurodegeneration; Oxidative stress; Pycnogenol

Indexed keywords

ACETYLCYSTEINE; ALPHA TOCOPHEROL; ANTIOXIDANT; BUTYLCRESOL; DEFEROXAMINE MESYLATE; FLAVONOID; GINKGO BILOBA EXTRACT; GLUTAMIC ACID; GLUTATHIONE DERIVATIVE; HERBACEOUS AGENT; LACTATE DEHYDROGENASE; PYCNOGENOL; QUERCETIN; RUTOSIDE; THIOCTIC ACID; TROLOX C;

ALZHEIMER DISEASE; ANIMAL CELL; ANTIOXIDANT ACTIVITY; ARTICLE; BRAIN ISCHEMIA; CELL LINE; CONTROLLED STUDY; CYTOTOXICITY; GLIA CELL; NEUROPROTECTION; NONHUMAN; OXIDATIVE STRESS; RAT;

EID: 0033955308     PISSN: 10715762     EISSN: None     Source Type: Journal    
DOI: 10.1080/10715760000300121     Document Type: Article

References (29)

1. J.T. Coyle and P. Puttfarcken (1993) Oxidative stress, glutamate, and neurodegenerative disorders. Science 262, 689-695.
2. M. Panigrahi, Y. Sadguna, B.R. Shivakumar, S.V. Kolluri, S. Roy, L. Packer and V. Ravindranath (1996) α-Lipoic acid protects against reperfusion injury following cerebral ischemia in rats. Brain Research 717, 184-188.
3. H. Kinouchi, C.J. Epstein, T. Mizui, E. Carlson, S.F. Chen and P.H. Chan (1991) Attenuation of focal cerebral ischemic injury in transgenic mice overexpressing CuZn superoxide dismutase. Proceedings of the National Academy of Sciences of the USA 88, 11 158-11 162.
4. M. Sano, C. Ernesto, R.G. Thomas, M.R. Klauber, K. Schafer, M. Grundman, P. Woodbury, J. Growdon, C.W. Cotman, E. Pfeiffer, L.S. Schneider and L.J. Thal (1997) A controlled trial of selegiline, α-tocopherol, or both as treatment for Alzheimer's disease. New England Journal of Medicine 336, 1216-1222.
5. P.L. Le Bars, M.M. Katz, N. Berman, T.M. Itil, A.M. Freedman and A.F. Schatzberg (1997) A placebo-controlled double-blind, randomized trial of an extract of Ginkgo biloba for dementia. Journal of the American Medical Association 278, 1327-1332.
6. C.N. Oliver, P.E. Starke-Reed, E.R. Stadtman, G.J. Liu, J.M. Carney and R.A. Floyd (1990) Oxidative damage to brain proteins, loss of glutamine synthetase activity, and production of free radicals during ischemia/reperfusion-induced injury to gerbil brain. Proceedings of the National Academy of Sciences of the USA 87, 5144-5147.
7. J.W. Olney (1969) Brain lesions, obesity, and other disturbances in mice treated with monosodium glutamate. Science 164, 719-721.
8. E. Ciani, L. Groneng, M. Voltattorni, V. Rolseth, A. Contestabile and R.E. Paulsen (1996) Inhibition of free radical production or free radical scavenging protects from the excitotoxic cell death mediated by glutamate in cultures of cerebellar granule neurons. Brain Research 728, 1-6.
9. U. Muller and J. Krieglstein (1995) Prolonged pretreatment with α-lipoic acid protects cultured neurons against hypoxic, glutamate-, or iron-induced injury. Journal of Cerebral Blood Flow and Metabolism 15, 624-630.
10. T.H. Murphy, M. Miyamoto, A. Sastre, R.L. Schnaar and J.T. Coyle (1989) Glutamate toxicity in a neuronal cell line involves inhibition of cystine transport leading to oxidative stress. Neuron 2, 1547-1558.
11. S. Kato, K. Negishi, K. Mawatari and C.H. Kuo (1992) A mechanism for glutamate toxicity in the C6 glioma cells involving inhibition of cystine uptake leading to glutathione depletion. Neuroscience 48, 903-914.
12. A. Oka, M.J. Belliveau, P.A. Rosenberg and J.J. Volpe (1993) Vulnerability of oligodendroglia to glutamate: pharmacology, mechanisms, and prevention. Journal of Neuroscience 13, 1441-1453.
13. P. Maher and J.B. Davis (1996) The role of monoamine metabolism in oxidative glutamate toxicity. Journal of Neuroscience 16, 6394-6401.
14. C.M. Pereira and C.R. Oliveira (1997) Glutamate toxicity on a PC12 cell line involves glutathione (GSH) depletion and oxidative stress. Free Radical Biology and Medicine 23, 637-647.
15. D. Han, C.K. Sen, S. Roy, M.S. Kobayashi, H.J. Tritschler and L. Packer (1997) Protection against glutamate-induced cytotoxicity in C6 glial cells by thiol antioxidants. American Journal of Physiology 273, R1771-R1778.
16. R.L. Schnaar, P.H. Weigel, M.S. Kuhlenschmidt, Y.C. Lee and S. Roseman (1978) Adhesion of chicken hepatocytes to polyacrylamide gels derivatized with N-acetyl glucosamine. Journal of Biological Chemistry 253, 7940-7951.
17. L.A. Allison and R.E. Shoup (1983) Dual-electrode liquid chromatography detector for thiols and disulfides. Analytical Chemistry 55, 8-12.
18. P.R. Harvey, R.G. Ilson and S.M. Strasberg (1989) The simultaneous determination of oxidized and reduced glutathiones in liver tissue by ion pairing reverse phase high performance liquid chromatography with a coulometric electrochemical detector. Clinica Chimica Acta 180, 203-212.
19. H. Esterbauer (1996) Estimation of peroxidative damage. A critical review. Pathologie Biologie 44, 25-28.
20. S.H. Wong, J.A. Knight, S.M. Hopfer, O. Zaharia, C.N. Leach Jr. and F.W. Sunderman Jr. (1987) Lipoperoxides in plasma as measured by liquid-chromatographic separation of malondialdehyde-thiobarbituric acid adduct. Clinical Chemistry 33, 214-220.
21. P. Jenner (1996) Oxidative stress in Parkinson's disease and other neurodegenerative disorders. Pathologie Biologie 44, 57-64.
22. O. Tirosh, C.K. Sen, S. Roy, M.S. Kobayashi and L. Packer (Abstract) Antioxidant defense mechanisms and oxidant involvement in glutamate induced apoptosis (March 17, 1998), Faseb Journal Abstracts: Experimental Biology 1998 12, A133.
23. D. Han, M.S. Kobayashi, E. Cadenas and L. Packer, Central role of lipid peroxidation in glutamate-induced cytotoxicity in HT-4 cells. (In preparation)
24. H. Kobuchi, M.T. Droy-Lefaix, Y. Christen and L. Packer (1997) Ginkgo biloba extract (EGb 761): inhibitory effect on nitric oxide production in the macrophage cell line RAW 264.7. Biochemical Pharmacology 53, 897-903.
25. F. Virgili, H. Kobuchi and L. Packer (1998) Procyanidins extracted from Pinus maritima (Pycnogenol®): scavengers of free radical species and modulators of nitrogen monoxide metabolism in activated murine RAW 264.7 macrophages. Free Radical Biology and Medicine 24, 1120-1129.
26. Y. Oyama, P.A. Fuchs, N. Katayama and K. Noda (1994) Myricetin and quercetin, the flavonoid constituents of Ginkgo biloba extract, greatly reduce oxidative metabolism in both resting and calcium-loaded brain neurons. Brain Research 635, 125-129.
27. J.D. Adams Jr. and I.N. Odunze (1991) Oxygen free radicals and Parkinson's disease. Free Radical Biology and Medicine 10, 161-169.
28. 14C] rac-α-lipoic acid from in situ ligated segments of the gastrointestinal tract of the rat. Arzneimittelforschung 45, 293-299.
29. J. Teichert and R. Preuss (1992) HPLC-methods for determination of lipoic acid and its reduced form in human plasma. International Journal of Clinical Pharmacology and Therapeutic Toxicology 30, 511-512.