메뉴 건너뛰기




Volumn 15, Issue 2, 2017, Pages 81-93

Pharmacology of mangostins and their derivatives: A comprehensive review

Author keywords

Derivatives; Mangostins; Pharmacokinetics; Pharmacological activities; Toxicology

Indexed keywords

AMYLOID BETA PROTEIN; ANTINEOPLASTIC AGENT; CHOLINESTERASE; MANGOSTIN DERIVATIVE; SPHINGOMYELIN PHOSPHODIESTERASE; UNCLASSIFIED DRUG; XANTHONE DERIVATIVE; ANTIINFECTIVE AGENT; ANTIOXIDANT; CARDIOVASCULAR AGENT; MANGOSTIN; NEUROPROTECTIVE AGENT; PLANT EXTRACT; PROTECTIVE AGENT;

EID: 85014870741     PISSN: 20956975     EISSN: 18755364     Source Type: Journal    
DOI: 10.1016/S1875-5364(17)30024-9     Document Type: Review
Times cited : (69)

References (117)
  • 2
    • 84904426935 scopus 로고    scopus 로고
    • α-Mangostin: a dietary antioxidant derived from the pericarp of Garcinia mangostana L. inhibits pancreatic tumor growth in xenograft mouse model [J]
    • 2 Hafeez, BB, Mustafa, A, Fischer, JW, et al. α-Mangostin: a dietary antioxidant derived from the pericarp of Garcinia mangostana L. inhibits pancreatic tumor growth in xenograft mouse model [J]. Antioxid Redox Signal 21:5 (2014), 682–699.
    • (2014) Antioxid Redox Signal , vol.21 , Issue.5 , pp. 682-699
    • Hafeez, B.B.1    Mustafa, A.2    Fischer, J.W.3
  • 3
    • 33645765822 scopus 로고    scopus 로고
    • Antioxidant xanthones from the pericarp of Garcinia mangostana (Mangosteen) [J]
    • 3 Jung, HA, Su, BN, Keller, WJ, et al. Antioxidant xanthones from the pericarp of Garcinia mangostana (Mangosteen) [J]. J Agric Food Chem 54:6 (2006), 2077–2082.
    • (2006) J Agric Food Chem , vol.54 , Issue.6 , pp. 2077-2082
    • Jung, H.A.1    Su, B.N.2    Keller, W.J.3
  • 4
    • 68049107045 scopus 로고    scopus 로고
    • Garcinia mangostana L.: A phytochemical and pharmacological review [J]
    • 4 Dmitriy, Obolskiy, Ivo, Pischel, Nisarat, Siriwatanametanon, et al. Garcinia mangostana L.: A phytochemical and pharmacological review [J]. Phytother Res 23 (2009), 1047–1065.
    • (2009) Phytother Res , vol.23 , pp. 1047-1065
    • Dmitriy, O.1    Ivo, P.2    Nisarat, S.3
  • 5
    • 84864883641 scopus 로고    scopus 로고
    • Artemisinin-resistant malaria: research challenges, opportunities, and public health implications [J]
    • 5 Rick, M Fairhurst, Gaurvika, ML Nayyar, Joel, G Breman, et al. Artemisinin-resistant malaria: research challenges, opportunities, and public health implications [J]. Am J Trop Med Hyg 87:2 (2012), 231–241.
    • (2012) Am J Trop Med Hyg , vol.87 , Issue.2 , pp. 231-241
    • Rick, M.F.1    Gaurvika, M.N.2    Joel, G.B.3
  • 6
    • 35948972121 scopus 로고    scopus 로고
    • Superbugs in the coming new decade; multidrug resistance and prospects for treatment of Staphylococcus aureus, Enterococcus spp. and Pseudomonas aeruginosa in 2010 [J]
    • 6 Nordmann, P, Naas, T, Fortineau, N, et al. Superbugs in the coming new decade; multidrug resistance and prospects for treatment of Staphylococcus aureus, Enterococcus spp. and Pseudomonas aeruginosa in 2010 [J]. Curr Opin Microbiol 10:5 (2007), 436–440.
    • (2007) Curr Opin Microbiol , vol.10 , Issue.5 , pp. 436-440
    • Nordmann, P.1    Naas, T.2    Fortineau, N.3
  • 7
    • 14844318574 scopus 로고    scopus 로고
    • Antibacterial activity of α-mangostin against vancomycin resistant Enterococci (VRE) and synergism with antibiotics [J]
    • 7 Sakagami, Y, Iinuma, M, Piyasena, K, et al. Antibacterial activity of α-mangostin against vancomycin resistant Enterococci (VRE) and synergism with antibiotics [J]. Phytomedicine 12:3 (2005), 203–208.
    • (2005) Phytomedicine , vol.12 , Issue.3 , pp. 203-208
    • Sakagami, Y.1    Iinuma, M.2    Piyasena, K.3
  • 8
    • 0029787729 scopus 로고    scopus 로고
    • Antibacterial activity of xanthones from guttiferaeous plants against methicillin-resistant Staphylococcus aureus [J]
    • 8 Iinuma, M, Tosa, H, Tanaka, T, et al. Antibacterial activity of xanthones from guttiferaeous plants against methicillin-resistant Staphylococcus aureus [J]. J Pharm Pharmacol 48:8 (1996), 861–865.
    • (1996) J Pharm Pharmacol , vol.48 , Issue.8 , pp. 861-865
    • Iinuma, M.1    Tosa, H.2    Tanaka, T.3
  • 9
    • 60349108788 scopus 로고    scopus 로고
    • Antibacterial activity of Thai medicinal plants against methicillin-resistant Staphylococcus aureus [J]
    • 9 Chomnawang, MT, Surassmo, S, Wongsariya, K, et al. Antibacterial activity of Thai medicinal plants against methicillin-resistant Staphylococcus aureus [J]. Fitoterapia 80:2 (2009), 102–104.
    • (2009) Fitoterapia , vol.80 , Issue.2 , pp. 102-104
    • Chomnawang, M.T.1    Surassmo, S.2    Wongsariya, K.3
  • 10
    • 84871738548 scopus 로고    scopus 로고
    • Rapid bactericidal action of α-mangostin against MRSA as an outcome of membrane targeting [J]
    • 10 Koh, JJ, Qiu, S, Zou, H, et al. Rapid bactericidal action of α-mangostin against MRSA as an outcome of membrane targeting [J]. Biochim Biophys Acta 1828:2 (2013), 834–844.
    • (2013) Biochim Biophys Acta , vol.1828 , Issue.2 , pp. 834-844
    • Koh, J.J.1    Qiu, S.2    Zou, H.3
  • 11
    • 84875731528 scopus 로고    scopus 로고
    • Design and synthesis of amphiphilic xanthone-based, membrane-targeting antimicrobials with improved membrane selectivity [J]
    • 11 Zou, H, Koh, JJ, Li, J, et al. Design and synthesis of amphiphilic xanthone-based, membrane-targeting antimicrobials with improved membrane selectivity [J]. J Med Chem 56:6 (2013), 2359–2373.
    • (2013) J Med Chem , vol.56 , Issue.6 , pp. 2359-2373
    • Zou, H.1    Koh, J.J.2    Li, J.3
  • 12
    • 84921495327 scopus 로고    scopus 로고
    • Amino acid modified xanthone derivatives: novel, highly promising membrane-active antimicrobials for multidrug-resistant Gram-positive bacterial infections [J]
    • 12 Koh, JJ, Lin, S, Aung, TT, et al. Amino acid modified xanthone derivatives: novel, highly promising membrane-active antimicrobials for multidrug-resistant Gram-positive bacterial infections [J]. J Med Chem 58:2 (2015), 739–752.
    • (2015) J Med Chem , vol.58 , Issue.2 , pp. 739-752
    • Koh, J.J.1    Lin, S.2    Aung, T.T.3
  • 13
    • 84921716888 scopus 로고    scopus 로고
    • A novel fragment based strategy for membrane active antimicrobials against MRSA [J]
    • 13 Li, J, Liu, S, Koh, JJ, et al. A novel fragment based strategy for membrane active antimicrobials against MRSA [J]. Biochim Biophys Acta 1848:4 (2015), 1023–1031.
    • (2015) Biochim Biophys Acta , vol.1848 , Issue.4 , pp. 1023-1031
    • Li, J.1    Liu, S.2    Koh, J.J.3
  • 14
    • 84879238325 scopus 로고    scopus 로고
    • Antibacterial activity of xanthones from Garcinia mangostana (L.) and their structure-activity relationship studies [J]
    • 14 Dharmaratne, HR, Sakagami, Y, Piyasena, KG, et al. Antibacterial activity of xanthones from Garcinia mangostana (L.) and their structure-activity relationship studies [J]. Nat Prod Res 27:10 (2013), 938–941.
    • (2013) Nat Prod Res , vol.27 , Issue.10 , pp. 938-941
    • Dharmaratne, H.R.1    Sakagami, Y.2    Piyasena, K.G.3
  • 15
    • 0033036473 scopus 로고    scopus 로고
    • Antimicrobial activity of xanthones from Calophyllum species, against methicillin-resistant Staphylococcus aureus (MRSA) [J]
    • 15 Dharmaratne, HR, Wijesinghe, WM, Thevanasem, V, Antimicrobial activity of xanthones from Calophyllum species, against methicillin-resistant Staphylococcus aureus (MRSA) [J]. J Ethnopharmacol 66:3 (1999), 339–342.
    • (1999) J Ethnopharmacol , vol.66 , Issue.3 , pp. 339-342
    • Dharmaratne, H.R.1    Wijesinghe, W.M.2    Thevanasem, V.3
  • 16
    • 79955900411 scopus 로고    scopus 로고
    • Natural products in caries research: current (limited) knowledge, challenges and future perspective [J]
    • 16 Jeon, JG, Rosalen, PL, Falsetta, ML, et al. Natural products in caries research: current (limited) knowledge, challenges and future perspective [J]. Caries Res 45:3 (2011), 243–263.
    • (2011) Caries Res , vol.45 , Issue.3 , pp. 243-263
    • Jeon, J.G.1    Rosalen, P.L.2    Falsetta, M.L.3
  • 17
    • 79952230322 scopus 로고    scopus 로고
    • Antimicrobial actions of α-mangostin against oral streptococci [J]
    • 17 Nguyen, PT, Marquis, RE, Antimicrobial actions of α-mangostin against oral streptococci [J]. Can J Microbiol 57:3 (2011), 217–225.
    • (2011) Can J Microbiol , vol.57 , Issue.3 , pp. 217-225
    • Nguyen, P.T.1    Marquis, R.E.2
  • 18
    • 84908568733 scopus 로고    scopus 로고
    • α-Mangostin disrupts the development of Streptococcus mutans biofilms and facilitates its mechanical removal [J]
    • 18 Nguyen, PT, Falsetta, ML, Hwang, G, et al. α-Mangostin disrupts the development of Streptococcus mutans biofilms and facilitates its mechanical removal [J]. PLoS One, 9(10), 2014, e111312.
    • (2014) PLoS One , vol.9 , Issue.10 , pp. e111312
    • Nguyen, P.T.1    Falsetta, M.L.2    Hwang, G.3
  • 19
    • 84902553178 scopus 로고    scopus 로고
    • Microbial diversity in persistent root canal infections investigated by checkerboard DNA-DNA hybridization [J]
    • 19 Murad, CF, Sassone, LM, Faveri, M, et al. Microbial diversity in persistent root canal infections investigated by checkerboard DNA-DNA hybridization [J]. J Endod 40:7 (2014), 899–906.
    • (2014) J Endod , vol.40 , Issue.7 , pp. 899-906
    • Murad, C.F.1    Sassone, L.M.2    Faveri, M.3
  • 20
    • 85014834466 scopus 로고    scopus 로고
    • Laboratory evaluation of the antibacterial and cytotoxic effect of alpha-mangostin when used as a root canal irrigant [J]
    • 20 Ruchadaporn, Kaomongkolgit, Kusuma, Jamdee, Jittima, Pumklin, et al. Laboratory evaluation of the antibacterial and cytotoxic effect of alpha-mangostin when used as a root canal irrigant [J]. Indian J Dent 4:1 (2013), 12–17.
    • (2013) Indian J Dent , vol.4 , Issue.1 , pp. 12-17
    • Ruchadaporn, K.1    Kusuma, J.2    Jittima, P.3
  • 21
    • 33847154291 scopus 로고    scopus 로고
    • A review of anti-infective and anti-inflammatory chalcones [J]
    • 21 Nowakowska, Z, A review of anti-infective and anti-inflammatory chalcones [J]. Eur J Med Chem 42:2 (2007), 125–137.
    • (2007) Eur J Med Chem , vol.42 , Issue.2 , pp. 125-137
    • Nowakowska, Z.1
  • 22
    • 1542785862 scopus 로고    scopus 로고
    • Antimycobacterial activity of prenylated xanthones from the fruits of Garcinia mangostana [J]
    • 22 Suksamrarn, S, Suwannapoch, N, Phakhodee, W, et al. Antimycobacterial activity of prenylated xanthones from the fruits of Garcinia mangostana [J]. Chem Pharm Bull (Tokyo) 51:7 (2003), 857–859.
    • (2003) Chem Pharm Bull (Tokyo) , vol.51 , Issue.7 , pp. 857-859
    • Suksamrarn, S.1    Suwannapoch, N.2    Phakhodee, W.3
  • 23
    • 84873593744 scopus 로고    scopus 로고
    • Potent activity against multidrug-resistant Mycobacterium tuberculosis of α-mangostin analogs [J]
    • 23 Sudta, P, Jiarawapi, P, Suksamrarn, A, et al. Potent activity against multidrug-resistant Mycobacterium tuberculosis of α-mangostin analogs [J]. Chem Pharm Bull (Tokyo) 61:2 (2013), 194–203.
    • (2013) Chem Pharm Bull (Tokyo) , vol.61 , Issue.2 , pp. 194-203
    • Sudta, P.1    Jiarawapi, P.2    Suksamrarn, A.3
  • 24
    • 79954597523 scopus 로고    scopus 로고
    • Microbial metabolism of α-mangostin isolated from Garcinia mangostana L. [J]
    • 24 Arunrattiyakorn, P, Suksamrarn, S, Suwannasai, N, et al. Microbial metabolism of α-mangostin isolated from Garcinia mangostana L. [J]. Phytochemistry 72:8 (2011), 730–734.
    • (2011) Phytochemistry , vol.72 , Issue.8 , pp. 730-734
    • Arunrattiyakorn, P.1    Suksamrarn, S.2    Suwannasai, N.3
  • 25
    • 0031007442 scopus 로고    scopus 로고
    • Evaluation of the antifungal activity of natural xanthones from Garcinia mangostana and their synthetic derivatives [J]
    • 25 Gopalakrishnan, G, Banumathi, B, Suresh, G, Evaluation of the antifungal activity of natural xanthones from Garcinia mangostana and their synthetic derivatives [J]. J Nat Prod 60:5 (1997), 519–524.
    • (1997) J Nat Prod , vol.60 , Issue.5 , pp. 519-524
    • Gopalakrishnan, G.1    Banumathi, B.2    Suresh, G.3
  • 26
    • 74049093215 scopus 로고    scopus 로고
    • Antifungal activity of α-mangostin against Candida albicans [J]
    • 26 Kaomongkolgit, R, Jamdee, K, Chaisomboon, N, Antifungal activity of α-mangostin against Candida albicans [J]. J Oral Sci 51:3 (2009), 401–406.
    • (2009) J Oral Sci , vol.51 , Issue.3 , pp. 401-406
    • Kaomongkolgit, R.1    Jamdee, K.2    Chaisomboon, N.3
  • 27
    • 84938750811 scopus 로고    scopus 로고
    • In vivo antimalarial activity of α-mangostin and the new xanthone δ-mangostin [J]
    • 27 Upegui, Y, Robledo, SM, Gil Romero, JF, et al. In vivo antimalarial activity of α-mangostin and the new xanthone δ-mangostin [J]. Phytother Res 29:8 (2015), 1195–1201.
    • (2015) Phytother Res , vol.29 , Issue.8 , pp. 1195-1201
    • Upegui, Y.1    Robledo, S.M.2    Gil Romero, J.F.3
  • 28
    • 33748592259 scopus 로고    scopus 로고
    • Prenylated xanthones as potential antiplasmodial substances [J]
    • 28 Mahabusarakam, W, Kuaha, K, Wilairat, P, et al. Prenylated xanthones as potential antiplasmodial substances [J]. Planta Med 72:10 (2006), 912–916.
    • (2006) Planta Med , vol.72 , Issue.10 , pp. 912-916
    • Mahabusarakam, W.1    Kuaha, K.2    Wilairat, P.3
  • 29
    • 0030961389 scopus 로고    scopus 로고
    • Xanthones as antimalarial agents; studies of a possible mode of action [J]
    • 29 Ignatushchenko, MV, Winter, RW, Bachinger, HP, et al. Xanthones as antimalarial agents; studies of a possible mode of action [J]. FEBS Lett 409:1 (1997), 67–73.
    • (1997) FEBS Lett , vol.409 , Issue.1 , pp. 67-73
    • Ignatushchenko, M.V.1    Winter, R.W.2    Bachinger, H.P.3
  • 30
    • 26044483551 scopus 로고    scopus 로고
    • Xanthones as antimalarial agents: discovery, mode of action, and optimization [J]
    • 30 Riscoe, M, Kelly, JX, Winter, R, Xanthones as antimalarial agents: discovery, mode of action, and optimization [J]. Curr Med Chem 12:21 (2005), 2539–2549.
    • (2005) Curr Med Chem , vol.12 , Issue.21 , pp. 2539-2549
    • Riscoe, M.1    Kelly, J.X.2    Winter, R.3
  • 31
    • 0036135320 scopus 로고    scopus 로고
    • Optimization of xanthones for antimalarial activity: the 3, 6-bis-omega-diethylaminoalkoxyxanthone series [J]
    • 31 Kelly, JX, Winter, R, Peyton, DH, et al. Optimization of xanthones for antimalarial activity: the 3, 6-bis-omega-diethylaminoalkoxyxanthone series [J]. Antimicrob Agents Chemother 46:1 (2002), 144–150.
    • (2002) Antimicrob Agents Chemother , vol.46 , Issue.1 , pp. 144-150
    • Kelly, J.X.1    Winter, R.2    Peyton, D.H.3
  • 32
    • 0037036620 scopus 로고    scopus 로고
    • The kinetics of uptake and accumulation of 3, 6-bis-omega-diethylaminoamyloxyxanthone by the human malaria parasite Plasmodium falciparum [J]
    • 32 Kelly, JX, Winter, RW, Cornea, A, et al. The kinetics of uptake and accumulation of 3, 6-bis-omega-diethylaminoamyloxyxanthone by the human malaria parasite Plasmodium falciparum [J]. Mol Biochem Parasitol 123:1 (2002), 47–54.
    • (2002) Mol Biochem Parasitol , vol.123 , Issue.1 , pp. 47-54
    • Kelly, J.X.1    Winter, R.W.2    Cornea, A.3
  • 33
    • 0042422298 scopus 로고    scopus 로고
    • Induction of apoptosis by xanthones from mangosteen in human leukemia cell lines [J]
    • 33 Matsumoto, K, Akao, Y, Kobayashi, E, et al. Induction of apoptosis by xanthones from mangosteen in human leukemia cell lines [J]. J Nat Prod 66:8 (2003), 1124–1127.
    • (2003) J Nat Prod , vol.66 , Issue.8 , pp. 1124-1127
    • Matsumoto, K.1    Akao, Y.2    Kobayashi, E.3
  • 34
    • 6344279799 scopus 로고    scopus 로고
    • Preferential target is mitochondria in α-mangostin-induced apoptosis in human leukemia HL60 cells [J]
    • 34 Matsumoto, K, Akao, Y, Yi, H, et al. Preferential target is mitochondria in α-mangostin-induced apoptosis in human leukemia HL60 cells [J]. Bioorg Med Chem 12:22 (2004), 5799–5806.
    • (2004) Bioorg Med Chem , vol.12 , Issue.22 , pp. 5799-5806
    • Matsumoto, K.1    Akao, Y.2    Yi, H.3
  • 35
    • 64549092413 scopus 로고    scopus 로고
    • Mangostin suppresses PC-3 human prostate carcinoma cell metastasis by inhibiting matrix metalloproteinase-2/9 and urokinase-plasminogen expression through the JNK signaling pathway [J]
    • 35 Hung, SHS, Wu, KH, Liu, CH, et al. Mangostin suppresses PC-3 human prostate carcinoma cell metastasis by inhibiting matrix metalloproteinase-2/9 and urokinase-plasminogen expression through the JNK signaling pathway [J]. J Agric Food Chem 57 (2009), 1291–1298.
    • (2009) J Agric Food Chem , vol.57 , pp. 1291-1298
    • Hung, S.H.S.1    Wu, K.H.2    Liu, C.H.3
  • 36
    • 34250705898 scopus 로고    scopus 로고
    • Characterized mechanism of R-mangostin-induced cell death: Caspaseindependent apoptosis with release of endonuclease-G from mitochondria and increased miR-143 expression in human colorectal cancer DLD-1 cells [J]
    • 36 Nakagawa, YI M, Naoe, T, Nozawa, Y, et al. Characterized mechanism of R-mangostin-induced cell death: Caspaseindependent apoptosis with release of endonuclease-G from mitochondria and increased miR-143 expression in human colorectal cancer DLD-1 cells [J]. Bioorg Med Chem 15 (2007), 5620–5628.
    • (2007) Bioorg Med Chem , vol.15 , pp. 5620-5628
    • Nakagawa, Y.M.1    Naoe, T.2    Nozawa, Y.3
  • 37
    • 84893207224 scopus 로고    scopus 로고
    • Inhibition of autophagy augments the anticancer activity of α-mangostin in chronic myeloid leukemia cells [J]
    • 37 Chen, JJ, Long, ZJ, Xu, DF, et al. Inhibition of autophagy augments the anticancer activity of α-mangostin in chronic myeloid leukemia cells [J]. Leuk Lymphoma 55:3 (2013), 628–638.
    • (2013) Leuk Lymphoma , vol.55 , Issue.3 , pp. 628-638
    • Chen, J.J.1    Long, Z.J.2    Xu, D.F.3
  • 39
    • 79960839037 scopus 로고    scopus 로고
    • Cytotoxic effect of xanthones from pericarp of the tropical fruit mangosteen (Garcinia mangostana Linn.) on human melanoma cells [J]
    • 39 Wang, JJ, Sanderson, BJ, Zhang, W, Cytotoxic effect of xanthones from pericarp of the tropical fruit mangosteen (Garcinia mangostana Linn.) on human melanoma cells [J]. Food Chem Toxicol 49:9 (2011), 2385–2391.
    • (2011) Food Chem Toxicol , vol.49 , Issue.9 , pp. 2385-2391
    • Wang, J.J.1    Sanderson, B.J.2    Zhang, W.3
  • 40
    • 84885660382 scopus 로고    scopus 로고
    • Altered mRNA expression related to the apoptotic effect of three xanthones on human melanoma SK-MEL-28 cell line [J]
    • 40 Wang, JJ, Zhang, W, Babara, JS Sanderson, Altered mRNA expression related to the apoptotic effect of three xanthones on human melanoma SK-MEL-28 cell line [J]. Biomed Res Int, 2013(5392), 2013, 715603.
    • (2013) Biomed Res Int , vol.2013 , Issue.5392 , pp. 715603
    • Wang, J.J.1    Zhang, W.2    Babara, J.S.3
  • 41
    • 84906083136 scopus 로고    scopus 로고
    • Inhibition of cell proliferation, migration and invasion of B16-F10 melanoma cells by α-mangostin [J]
    • 41 Beninati, S, Oliverio, S, Cordella, M, et al. Inhibition of cell proliferation, migration and invasion of B16-F10 melanoma cells by α-mangostin [J]. Biochem Biophys Res Commun 450:4 (2014), 1512–1517.
    • (2014) Biochem Biophys Res Commun , vol.450 , Issue.4 , pp. 1512-1517
    • Beninati, S.1    Oliverio, S.2    Cordella, M.3
  • 42
    • 84866988376 scopus 로고    scopus 로고
    • Significant anti-invasive activities of α-mangostin from the mangosteen pericarp on two human skin cancer cell lines [J]
    • 42 Wang, JJ, Sanderson, BJ, Zhang, W, Significant anti-invasive activities of α-mangostin from the mangosteen pericarp on two human skin cancer cell lines [J]. Anticancer Res 32:9 (2012), 3805–3816.
    • (2012) Anticancer Res , vol.32 , Issue.9 , pp. 3805-3816
    • Wang, J.J.1    Sanderson, B.J.2    Zhang, W.3
  • 43
    • 0035029551 scopus 로고    scopus 로고
    • Ultraviolet A and melanoma: a review [J]
    • 43 Wang, SQ, Setlow, R, Berwick, M, et al. Ultraviolet A and melanoma: a review [J]. J Am Acad Dermatol 44:5 (2001), 837–846.
    • (2001) J Am Acad Dermatol , vol.44 , Issue.5 , pp. 837-846
    • Wang, S.Q.1    Setlow, R.2    Berwick, M.3
  • 44
    • 85008486481 scopus 로고    scopus 로고
    • Sunscreen activity of α-mangostin from the pericarps of Garcinia mangostana Linn [J]
    • 44 Iwo, MI, Soemardji, AA, Hanafi, M, Sunscreen activity of α-mangostin from the pericarps of Garcinia mangostana Linn [J]. J Appl Pharm Sci 3 (2013), 70–73.
    • (2013) J Appl Pharm Sci , vol.3 , pp. 70-73
    • Iwo, M.I.1    Soemardji, A.A.2    Hanafi, M.3
  • 45
    • 79954415478 scopus 로고    scopus 로고
    • Apoptotic effect of α-mangostin on head and neck squamous carcinoma cells [J]
    • 45 Kaomongkolgit, R, Chaisomboon, N, Pavasant, P, Apoptotic effect of α-mangostin on head and neck squamous carcinoma cells [J]. Arch. Oral Biol 56:5 (2011), 483–490.
    • (2011) Arch. Oral Biol , vol.56 , Issue.5 , pp. 483-490
    • Kaomongkolgit, R.1    Chaisomboon, N.2    Pavasant, P.3
  • 46
    • 79952170983 scopus 로고    scopus 로고
    • α-Mangostin, a dietary xanthone, induces autophagic cell death by activating the AMP-activated protein kinase pathway in glioblastoma cells [J]
    • 46 Chao, AC, Hsu, YL, Liu, CK, et al. α-Mangostin, a dietary xanthone, induces autophagic cell death by activating the AMP-activated protein kinase pathway in glioblastoma cells [J]. J Agric Food Chem 59:5 (2011), 2086–2096.
    • (2011) J Agric Food Chem , vol.59 , Issue.5 , pp. 2086-2096
    • Chao, A.C.1    Hsu, Y.L.2    Liu, C.K.3
  • 47
    • 79952170983 scopus 로고    scopus 로고
    • r-Mangostin, a dietary xanthone, induces autophagic cell death by activating the AMP-activated protein kinase pathway in glioblastoma cells [J]
    • 47 Chao, AC, Hsu, YL, Liu, CK, et al. r-Mangostin, a dietary xanthone, induces autophagic cell death by activating the AMP-activated protein kinase pathway in glioblastoma cells [J]. J Agric Food Chem 59 (2011), 2086–2096.
    • (2011) J Agric Food Chem , vol.59 , pp. 2086-2096
    • Chao, A.C.1    Hsu, Y.L.2    Liu, C.K.3
  • 48
    • 84908665091 scopus 로고    scopus 로고
    • Involvement of NF-κB and HSP70 signaling pathways in the apoptosis of MDA-MB-231 cells induced by a prenylated xanthone compound, α-mangostin, from Cratoxylum arborescens [J]
    • 48 Ibrahim, MY, Mohd Hashim, N, Mohan, S, et al. Involvement of NF-κB and HSP70 signaling pathways in the apoptosis of MDA-MB-231 cells induced by a prenylated xanthone compound, α-mangostin, from Cratoxylum arborescens [J]. Drug Des Devel Ther 8 (2014), 2193–2211.
    • (2014) Drug Des Devel Ther , vol.8 , pp. 2193-2211
    • Ibrahim, M.Y.1    Mohd Hashim, N.2    Mohan, S.3
  • 49
    • 84908069751 scopus 로고    scopus 로고
    • α-Mangostin from Cratoxylum arborescens demonstrates apoptogenesis in MCF-7 with regulation of NF-κB and HSP70 protein modulation in vitro, and tumor reduction in vivo [J]
    • 49 Ibrahim, MY, Hashim, NM, Mohan, S, et al. α-Mangostin from Cratoxylum arborescens demonstrates apoptogenesis in MCF-7 with regulation of NF-κB and HSP70 protein modulation in vitro, and tumor reduction in vivo [J]. Drug Des Devel Ther 8 (2014), 1629–1647.
    • (2014) Drug Des Devel Ther , vol.8 , pp. 1629-1647
    • Ibrahim, M.Y.1    Hashim, N.M.2    Mohan, S.3
  • 50
    • 84895067902 scopus 로고    scopus 로고
    • 2/M cell cycle arrest and apoptosis through ROS mediated mitochondrial pathway and NF-κB suppression in MCF-7 cells [J]
    • 2/M cell cycle arrest and apoptosis through ROS mediated mitochondrial pathway and NF-κB suppression in MCF-7 cells [J]. J Func Foods 6 (2014), 290–304.
    • (2014) J Func Foods , vol.6 , pp. 290-304
    • Syam, S.1    Bustamam, A.2    Abdullah, R.3
  • 51
    • 84902681731 scopus 로고    scopus 로고
    • α-Mangostin inhibits intracellular fatty acid synthase and induces apoptosis in breast cancer cells [J]
    • 51 Li, P, Tian, W, Ma, X, α-Mangostin inhibits intracellular fatty acid synthase and induces apoptosis in breast cancer cells [J]. Mol Cancer, 13, 2014, 138.
    • (2014) Mol Cancer , vol.13 , pp. 138
    • Li, P.1    Tian, W.2    Ma, X.3
  • 52
    • 84894114125 scopus 로고    scopus 로고
    • α-Mangostin-induced apoptosis is mediated by estrogen receptor α in human breast cancer cells [J]
    • 52 Won, YS, Lee, JH, Kwon, SJ, et al. α-Mangostin-induced apoptosis is mediated by estrogen receptor α in human breast cancer cells [J]. Food Chem Toxicol 66 (2014), 158–165.
    • (2014) Food Chem Toxicol , vol.66 , pp. 158-165
    • Won, Y.S.1    Lee, J.H.2    Kwon, S.J.3
  • 53
    • 84876902872 scopus 로고    scopus 로고
    • α-Mangostin and gambogic acid as potential inhibitors of the p53–MDM2 interaction revealed by a yeast approach [J]
    • 53 Leão, M, Gomes, S, Pedraza-Chaverri, J, et al. α-Mangostin and gambogic acid as potential inhibitors of the p53–MDM2 interaction revealed by a yeast approach [J]. J Nat Prod 76:4 (2013), 774–778.
    • (2013) J Nat Prod , vol.76 , Issue.4 , pp. 774-778
    • Leão, M.1    Gomes, S.2    Pedraza-Chaverri, J.3
  • 54
    • 79957877575 scopus 로고    scopus 로고
    • α-Mangostin extracted from the pericarp of the mangosteen (Garcinia mangostana Linn.) reduces tumor growth and lymph node metastasis in an immunocompetent xenograft model of metastatic mammary cancer carrying a p53 mutation [J]
    • 54 Shibata, MA, Iinuma, M, Morimoto, J, et al. α-Mangostin extracted from the pericarp of the mangosteen (Garcinia mangostana Linn.) reduces tumor growth and lymph node metastasis in an immunocompetent xenograft model of metastatic mammary cancer carrying a p53 mutation [J]. BMC Med, 9(1), 2011, 69.
    • (2011) BMC Med , vol.9 , Issue.1 , pp. 69
    • Shibata, M.A.1    Iinuma, M.2    Morimoto, J.3
  • 55
    • 84863044558 scopus 로고    scopus 로고
    • α-Mangostin, a xanthone from mangosteen fruit, promotes cell cycle arrest in prostate cancer and decreases xenograft tumor growth [J]
    • 55 Johnson, JJ, Petiwala, SM, Syed, DN, et al. α-Mangostin, a xanthone from mangosteen fruit, promotes cell cycle arrest in prostate cancer and decreases xenograft tumor growth [J]. Carcinogenesis 33:2 (2012), 413–419.
    • (2012) Carcinogenesis , vol.33 , Issue.2 , pp. 413-419
    • Johnson, J.J.1    Petiwala, S.M.2    Syed, D.N.3
  • 56
    • 84908338032 scopus 로고    scopus 로고
    • Inhibition of CHOP accentuates the apoptotic effect of α-mangostin from the mangosteen fruit (Garcinia mangostana) in 22Rv1 prostate cancer cells [J]
    • 56 Li, G, Petiwala, SM, Nonn, L, et al. Inhibition of CHOP accentuates the apoptotic effect of α-mangostin from the mangosteen fruit (Garcinia mangostana) in 22Rv1 prostate cancer cells [J]. Biochem Biophys Res Commun 453:1 (2014), 75–80.
    • (2014) Biochem Biophys Res Commun , vol.453 , Issue.1 , pp. 75-80
    • Li, G.1    Petiwala, S.M.2    Nonn, L.3
  • 57
    • 84893191004 scopus 로고    scopus 로고
    • Selective modulation of endoplasmic reticulum stress markers in prostate cancer cells by a standardized mangosteen fruit extract [J]
    • 57 Li, G, Petiwala, SM, Pierce, DR, et al. Selective modulation of endoplasmic reticulum stress markers in prostate cancer cells by a standardized mangosteen fruit extract [J]. PLoS One, 8(12), 2013, e81572.
    • (2013) PLoS One , vol.8 , Issue.12 , pp. e81572
    • Li, G.1    Petiwala, S.M.2    Pierce, D.R.3
  • 58
    • 84905666884 scopus 로고    scopus 로고
    • α-Mangostin suppresses human gastric adenocarcinoma cells in vitro via blockade of STAT3 signaling pathway [J]
    • 58 Shan, T, Cui, XJ, Li, W, et al. α-Mangostin suppresses human gastric adenocarcinoma cells in vitro via blockade of STAT3 signaling pathway [J]. Acta Pharmacol Sin 35:8 (2014), 1065–1073.
    • (2014) Acta Pharmacol Sin , vol.35 , Issue.8 , pp. 1065-1073
    • Shan, T.1    Cui, X.J.2    Li, W.3
  • 59
    • 85014838048 scopus 로고    scopus 로고
    • Inhibitory effect of α-mangostin on colon carcinogenesis induced by azoxymethane plus dextran sulfate sodium in CD1 (ICR) mice [J]
    • 59 Arakaki, J, Sunagawa, N, Chiba, I, et al. Inhibitory effect of α-mangostin on colon carcinogenesis induced by azoxymethane plus dextran sulfate sodium in CD1 (ICR) mice [J]. Cancer Res, 67(9 Supplement), 2007, 4974.
    • (2007) Cancer Res , vol.67 , Issue.9 Supplement , pp. 4974
    • Arakaki, J.1    Sunagawa, N.2    Chiba, I.3
  • 60
    • 16644370363 scopus 로고    scopus 로고
    • Inhibitory effects of crude α-mangostin, a xanthone derivative, on two different categorie of colon preneoplastic lesions induced by 1, 2-dimethylhydrazine in the rat [J]
    • 60 Nabandith, V, Suzui, M, Morioka, T, et al. Inhibitory effects of crude α-mangostin, a xanthone derivative, on two different categorie of colon preneoplastic lesions induced by 1, 2-dimethylhydrazine in the rat [J]. Asian Pac J Cancer Prev 5:4 (2004), 433–438.
    • (2004) Asian Pac J Cancer Prev , vol.5 , Issue.4 , pp. 433-438
    • Nabandith, V.1    Suzui, M.2    Morioka, T.3
  • 61
    • 84866603559 scopus 로고    scopus 로고
    • In vitro and in vivo anti-colon cancer effects of Garcinia mangostana xanthones extract [J]
    • 61 Aisha, AF, Abu-Salah, KM, Ismail, Z, et al. In vitro and in vivo anti-colon cancer effects of Garcinia mangostana xanthones extract [J]. BMC Complement Altern Med, 12(1), 2012, 104.
    • (2012) BMC Complement Altern Med , vol.12 , Issue.1 , pp. 104
    • Aisha, A.F.1    Abu-Salah, K.M.2    Ismail, Z.3
  • 62
    • 77955920713 scopus 로고    scopus 로고
    • Potential of xanthones from tropical fruit mangosteen as anti-cancer agents: caspase-dependent apoptosis induction in vitro and in mice [J]
    • 62 Watanapokasin, R, Jarinthanan, F, Jerusalmi, A, et al. Potential of xanthones from tropical fruit mangosteen as anti-cancer agents: caspase-dependent apoptosis induction in vitro and in mice [J]. Appl Biochem Biotech 162:4 (2010), 1080–1094.
    • (2010) Appl Biochem Biotech , vol.162 , Issue.4 , pp. 1080-1094
    • Watanapokasin, R.1    Jarinthanan, F.2    Jerusalmi, A.3
  • 63
    • 84872793155 scopus 로고    scopus 로고
    • Anti-tumorigenicity of dietary α-mangostin in an HT-29 colon cell xenograft model and the tissue distribution of xanthones and their phase II metabolites [J]
    • 63 Chitchumroonchokchai, C, Thomas-Ahner, JM, Li, J, et al. Anti-tumorigenicity of dietary α-mangostin in an HT-29 colon cell xenograft model and the tissue distribution of xanthones and their phase II metabolites [J]. Mol Nutr Food Res 57:2 (2013), 203–211.
    • (2013) Mol Nutr Food Res , vol.57 , Issue.2 , pp. 203-211
    • Chitchumroonchokchai, C.1    Thomas-Ahner, J.M.2    Li, J.3
  • 64
    • 34250705898 scopus 로고    scopus 로고
    • Characterized mechanism of α-mangostin-induced cell death: Caspase-independent apoptosis with release of endonuclease-G from mitochondria and increased miR-143 expression in human colorectal cancer DLD-1 cells [J]
    • 64 Nakagawa, Y, Iinuma, M, Naoe, T, et al. Characterized mechanism of α-mangostin-induced cell death: Caspase-independent apoptosis with release of endonuclease-G from mitochondria and increased miR-143 expression in human colorectal cancer DLD-1 cells [J]. Bioorg Med Chem 15:16 (2007), 5620–5628.
    • (2007) Bioorg Med Chem , vol.15 , Issue.16 , pp. 5620-5628
    • Nakagawa, Y.1    Iinuma, M.2    Naoe, T.3
  • 65
    • 80051791437 scopus 로고    scopus 로고
    • α-and γ-Mangostin inhibit the proliferation of colon cancer cells via β-catenin gene regulation in Wnt/cGMP signalling [J]
    • 65 Yoo, J-H, Kang, K, Jho, EH, et al. α-and γ-Mangostin inhibit the proliferation of colon cancer cells via β-catenin gene regulation in Wnt/cGMP signalling [J]. Food Chem 129:4 (2011), 1559–1566.
    • (2011) Food Chem , vol.129 , Issue.4 , pp. 1559-1566
    • Yoo, J.-H.1    Kang, K.2    Jho, E.H.3
  • 66
    • 84883055110 scopus 로고    scopus 로고
    • Inhibitory effects of α-mangostin on mammalian DNA polymerase, topoisomerase, and human cancer cell proliferation [J]
    • 66 Mizushina, Y, Kuriyama, I, Nakahara, T, et al. Inhibitory effects of α-mangostin on mammalian DNA polymerase, topoisomerase, and human cancer cell proliferation [J]. Food Chem Toxicol 59 (2013), 793–800.
    • (2013) Food Chem Toxicol , vol.59 , pp. 793-800
    • Mizushina, Y.1    Kuriyama, I.2    Nakahara, T.3
  • 67
    • 85031651463 scopus 로고    scopus 로고
    • 1 phase: Involvement of Ras, Hedgehog, NF-κB, and STAT3 signaling networks [J]
    • 1 phase: Involvement of Ras, Hedgehog, NF-κB, and STAT3 signaling networks [J]. Cancer Res, 70(8 Supplement), 2010, 3800.
    • (2010) Cancer Res , vol.70 , Issue.8 Supplement , pp. 3800
    • Hafeez, B.B.1    Dreckschmidt, N.E.2    Colson, L.A.3
  • 68
    • 85031653911 scopus 로고    scopus 로고
    • α-Mangostin, a dietary xanthone, inhibits ectopic xenograft growth of pancreatic cancer cells in an athymic nude mice [J]
    • 68 Hafeez, BB, Fischer, JW, Mustafa, A, et al. α-Mangostin, a dietary xanthone, inhibits ectopic xenograft growth of pancreatic cancer cells in an athymic nude mice [J]. Cancer Res, 72(8 Supplement), 2012, 5418.
    • (2012) Cancer Res , vol.72 , Issue.8 Supplement , pp. 5418
    • Hafeez, B.B.1    Fischer, J.W.2    Mustafa, A.3
  • 69
    • 84876497922 scopus 로고    scopus 로고
    • α-Mangostin suppresses lipopolysaccharide-induced invasion by inhibiting matrix metalloproteinase-2/9 and increasing E-cadherin expression through extracellular signal-regulated kinase signaling in pancreatic cancer cells [J]
    • 69 Yuan, J, Wu, Y, Lu, G, α-Mangostin suppresses lipopolysaccharide-induced invasion by inhibiting matrix metalloproteinase-2/9 and increasing E-cadherin expression through extracellular signal-regulated kinase signaling in pancreatic cancer cells [J]. Oncology Lett 5:6 (2013), 1958–1964.
    • (2013) Oncology Lett , vol.5 , Issue.6 , pp. 1958-1964
    • Yuan, J.1    Wu, Y.2    Lu, G.3
  • 70
    • 84899995986 scopus 로고    scopus 로고
    • α-Mangostin suppresses the viability and epithelial-mesenchymal transition of pancreatic cancer cells by down-regulating the PI3K/Akt pathway [J]
    • 70 Xu, Q, Ma, J, Lei, J, et al. α-Mangostin suppresses the viability and epithelial-mesenchymal transition of pancreatic cancer cells by down-regulating the PI3K/Akt pathway [J]. BioMed Res Int, 2014(6), 2014, 546353.
    • (2014) BioMed Res Int , vol.2014 , Issue.6 , pp. 546353
    • Xu, Q.1    Ma, J.2    Lei, J.3
  • 71
    • 84897081164 scopus 로고    scopus 로고
    • α-Mangostin inhibits hypoxia-driven ROS-induced PSC activation and pancreatic cancer cell invasion [J]
    • 71 Lei, J, Huo, X, Duan, W, et al. α-Mangostin inhibits hypoxia-driven ROS-induced PSC activation and pancreatic cancer cell invasion [J]. Cancer Lett 347:1 (2014), 129–138.
    • (2014) Cancer Lett , vol.347 , Issue.1 , pp. 129-138
    • Lei, J.1    Huo, X.2    Duan, W.3
  • 72
    • 80053999477 scopus 로고    scopus 로고
    • Xanthones from mangosteen extracts as natural chemopreventive agents: potential anticancer drugs [J]
    • 72 Shan, QM, Guo, K, Liu, J, et al. Xanthones from mangosteen extracts as natural chemopreventive agents: potential anticancer drugs [J]. Curr Mol Med 11:8 (2011), 666–677.
    • (2011) Curr Mol Med , vol.11 , Issue.8 , pp. 666-677
    • Shan, Q.M.1    Guo, K.2    Liu, J.3
  • 73
    • 70350532742 scopus 로고    scopus 로고
    • Renoprotection by α-mangostin is related to the attenuation in renal oxidative/nitrosative stress induced by cisplatin nephrotoxicity [J]
    • 73 Jazmin, M, Pe´rez-rojasl, CC, Dolores, J. Sa´nchez-gonzalez, et al. Renoprotection by α-mangostin is related to the attenuation in renal oxidative/nitrosative stress induced by cisplatin nephrotoxicity [J]. Free Radic Res 43:11 (2009), 1122–1132.
    • (2009) Free Radic Res , vol.43 , Issue.11 , pp. 1122-1132
    • Jazmin, M.1    Pe´rez-rojasl, C.C.2    Dolores, J.S.-G.3
  • 74
    • 77956170473 scopus 로고    scopus 로고
    • The α-mangostin prevention on cisplatin-induced apoptotic death in LLC-PK1 cells is associated to an inhibition of ROS production and p53 induction [J]
    • 74 Sanchez-Perez, Y, Morales-Barcenas, R, Garcia-Cuellar, CM, et al. The α-mangostin prevention on cisplatin-induced apoptotic death in LLC-PK1 cells is associated to an inhibition of ROS production and p53 induction [J]. Chem Biol Interact 188:1 (2010), 144–150.
    • (2010) Chem Biol Interact , vol.188 , Issue.1 , pp. 144-150
    • Sanchez-Perez, Y.1    Morales-Barcenas, R.2    Garcia-Cuellar, C.M.3
  • 75
    • 70350532742 scopus 로고    scopus 로고
    • Renoprotection by α-mangostin is related to the attenuation in renal oxidative/nitrosative stress induced by cisplatin nephrotoxicity [J]
    • 75 Perez-Rojas, JM, Cruz, C, Garcia-Lopez, P, et al. Renoprotection by α-mangostin is related to the attenuation in renal oxidative/nitrosative stress induced by cisplatin nephrotoxicity [J]. Free Radic Res 43:11 (2009), 1122–1132.
    • (2009) Free Radic Res , vol.43 , Issue.11 , pp. 1122-1132
    • Perez-Rojas, J.M.1    Cruz, C.2    Garcia-Lopez, P.3
  • 76
    • 78951481922 scopus 로고    scopus 로고
    • Doxorubicin-induced central nervous system toxicity and protection by xanthone derivative of Garcinia mangostana [J]
    • 76 Tangpong, J, Miriyala, S, Noel, T, et al. Doxorubicin-induced central nervous system toxicity and protection by xanthone derivative of Garcinia mangostana [J]. Neuroscience 175 (2011), 292–299.
    • (2011) Neuroscience , vol.175 , pp. 292-299
    • Tangpong, J.1    Miriyala, S.2    Noel, T.3
  • 77
    • 79957802468 scopus 로고    scopus 로고
    • Cytotoxic and NF-κB inhibitory constituents of the stems of Cratoxylum cochinchinense and their semisynthetic analogues [J]
    • 77 Ren, Y, Matthew, S, Lantvit, DD, et al. Cytotoxic and NF-κB inhibitory constituents of the stems of Cratoxylum cochinchinense and their semisynthetic analogues [J]. J Nat Prod 74:5 (2011), 1117–1125.
    • (2011) J Nat Prod , vol.74 , Issue.5 , pp. 1117-1125
    • Ren, Y.1    Matthew, S.2    Lantvit, D.D.3
  • 78
    • 68149092675 scopus 로고    scopus 로고
    • Cytotoxic geranylated xanthones and O-alkylated derivatives of α-mangostin [J]
    • 78 Ha, LD, Hansen, PE, Vang, O, et al. Cytotoxic geranylated xanthones and O-alkylated derivatives of α-mangostin [J]. Chem Pharm Bull (Tokyo) 57:8 (2009), 830–834.
    • (2009) Chem Pharm Bull (Tokyo) , vol.57 , Issue.8 , pp. 830-834
    • Ha, L.D.1    Hansen, P.E.2    Vang, O.3
  • 79
    • 84899062231 scopus 로고    scopus 로고
    • Synthesis of xanthone derivatives based on α-mangostin and their biological evaluation for anti-cancer agents [J]
    • 79 Fei, X, Jo, M, Lee, B, et al. Synthesis of xanthone derivatives based on α-mangostin and their biological evaluation for anti-cancer agents [J]. Bioorg Med Chem Lett 24:9 (2014), 2062–2065.
    • (2014) Bioorg Med Chem Lett , vol.24 , Issue.9 , pp. 2062-2065
    • Fei, X.1    Jo, M.2    Lee, B.3
  • 80
    • 84904548349 scopus 로고    scopus 로고
    • Specific glycosylated metabolites of α-mangostin by Cunninghamella blakesleana [J]
    • 80 He, L, Zhu, C, Yuan, Y, et al. Specific glycosylated metabolites of α-mangostin by Cunninghamella blakesleana [J]. Phytochem Lett 9 (2014), 175–178.
    • (2014) Phytochem Lett , vol.9 , pp. 175-178
    • He, L.1    Zhu, C.2    Yuan, Y.3
  • 81
    • 0026421457 scopus 로고
    • The significance of oxidized lipoproteins for the development of atherosclerosis. Antioxidants as a therapeutic alternative in atherosclerosis [J]
    • 81 Boberg, KM, The significance of oxidized lipoproteins for the development of atherosclerosis. Antioxidants as a therapeutic alternative in atherosclerosis [J]. Tidsskr Nor Laegeforen 111:15 (1991), 1861–1865.
    • (1991) Tidsskr Nor Laegeforen , vol.111 , Issue.15 , pp. 1861-1865
    • Boberg, K.M.1
  • 82
    • 4644310560 scopus 로고    scopus 로고
    • Role of oxidative modifications in atherosclerosis [J]
    • 82 Stocker, R, Keaney, JF Jr, Role of oxidative modifications in atherosclerosis [J]. Physiol Rev 84:4 (2004), 1381–1478.
    • (2004) Physiol Rev , vol.84 , Issue.4 , pp. 1381-1478
    • Stocker, R.1    Keaney, J.F.2
  • 83
    • 0029143672 scopus 로고
    • Mangostin inhibits the oxidative modification of human low density lipoprotein [J]
    • 83 Williams, P, Ongsakul, M, Proudfoot, J, et al. Mangostin inhibits the oxidative modification of human low density lipoprotein [J]. Free Radic Res 23:2 (1995), 175–184.
    • (1995) Free Radic Res , vol.23 , Issue.2 , pp. 175-184
    • Williams, P.1    Ongsakul, M.2    Proudfoot, J.3
  • 84
    • 0034493208 scopus 로고    scopus 로고
    • Inhibition of lipoprotein oxidation by prenylated xanthones derived from mangostin [J]
    • 84 Mahabusarakam, W, Proudfoot, J, Taylor, W, et al. Inhibition of lipoprotein oxidation by prenylated xanthones derived from mangostin [J]. Free Radic Res 33:5 (2000), 643–659.
    • (2000) Free Radic Res , vol.33 , Issue.5 , pp. 643-659
    • Mahabusarakam, W.1    Proudfoot, J.2    Taylor, W.3
  • 85
    • 84907312920 scopus 로고    scopus 로고
    • 2, HIF-1α, NF-κB, and iNOS inhibition by mangosteen pericarp ethanolic extract (Garcinia mangostana Linn) in hypercholesterol-diet-given Rattus norvegicus Wistar strain [J]
    • 2, HIF-1α, NF-κB, and iNOS inhibition by mangosteen pericarp ethanolic extract (Garcinia mangostana Linn) in hypercholesterol-diet-given Rattus norvegicus Wistar strain [J]. Vasc Health Risk Manag 10 (2014), 523–531.
    • (2014) Vasc Health Risk Manag , vol.10 , pp. 523-531
    • Wihastuti, T.A.1    Sargowo, D.2    Tjokroprawiro, A.3
  • 86
    • 84907376872 scopus 로고    scopus 로고
    • Effect of extract from pericarp of mangosteen as antioxidant rats models of atherosclerosis [J]
    • 86 Sargowo, D, Setiawan, M, Effect of extract from pericarp of mangosteen as antioxidant rats models of atherosclerosis [J]. Jurnal Kardiologi, 33, 2012, 71.
    • (2012) Jurnal Kardiologi , vol.33 , pp. 71
    • Sargowo, D.1    Setiawan, M.2
  • 87
    • 77955674124 scopus 로고    scopus 로고
    • Synthetic studies of mangostin derivatives with an inhibitory activity on PDGF-induced human aortic smooth cells proliferation [J]
    • 87 Nishihama, Y, Ogamino, T, Shi, WL, et al. Synthetic studies of mangostin derivatives with an inhibitory activity on PDGF-induced human aortic smooth cells proliferation [J]. Heterocycles 77:2 (2009), 759–765.
    • (2009) Heterocycles , vol.77 , Issue.2 , pp. 759-765
    • Nishihama, Y.1    Ogamino, T.2    Shi, W.L.3
  • 88
    • 53449098208 scopus 로고    scopus 로고
    • Acid sphingomyelinase promotes lipoprotein retention within early atheromata and accelerates lesion progression [J]
    • 88 Devlin, CM, Leventhal, AR, Kuriakose, G, et al. Acid sphingomyelinase promotes lipoprotein retention within early atheromata and accelerates lesion progression [J]. Arterioscler Thromb Vasc Biol 28:10 (2008), 1723–1730.
    • (2008) Arterioscler Thromb Vasc Biol , vol.28 , Issue.10 , pp. 1723-1730
    • Devlin, C.M.1    Leventhal, A.R.2    Kuriakose, G.3
  • 89
    • 0034092996 scopus 로고    scopus 로고
    • Inhibition of acidic sphingomyelinase by xanthone compounds isolated from Garcinia speciosa [J]
    • 89 Okudaira, C, Ikeda, Y, Kondo, S, et al. Inhibition of acidic sphingomyelinase by xanthone compounds isolated from Garcinia speciosa [J]. J Enzym Inhib Med Chem 15:2 (2000), 129–138.
    • (2000) J Enzym Inhib Med Chem , vol.15 , Issue.2 , pp. 129-138
    • Okudaira, C.1    Ikeda, Y.2    Kondo, S.3
  • 90
    • 0042332043 scopus 로고    scopus 로고
    • Biological activities of α-mangostin derivatives against acidic sphingomyelinase [J]
    • 90 Hamada, M, Iikubo, K, Ishikawa, Y, et al. Biological activities of α-mangostin derivatives against acidic sphingomyelinase [J]. Bioorg Med Chem Lett 13:19 (2003), 3151–3153.
    • (2003) Bioorg Med Chem Lett , vol.13 , Issue.19 , pp. 3151-3153
    • Hamada, M.1    Iikubo, K.2    Ishikawa, Y.3
  • 91
    • 84925298396 scopus 로고    scopus 로고
    • Design, synthesis and biological activity of acid sphingomyelinase inhibitors [J]
    • 91 Yang, K, Zhang, KJ, Hu, SY, et al. Design, synthesis and biological activity of acid sphingomyelinase inhibitors [J]. Chem J Chin Univ 36:2 (2015), 279–286.
    • (2015) Chem J Chin Univ , vol.36 , Issue.2 , pp. 279-286
    • Yang, K.1    Zhang, K.J.2    Hu, S.Y.3
  • 92
    • 75149165246 scopus 로고    scopus 로고
    • Synthesis, biological evaluation, and molecular modeling of berberine derivatives as potent acetylcholinesterase inhibitors [J]
    • 92 Huang, L, Shi, A, He, F, et al. Synthesis, biological evaluation, and molecular modeling of berberine derivatives as potent acetylcholinesterase inhibitors [J]. Bioorg Med Chem 18:3 (2010), 1244–1251.
    • (2010) Bioorg Med Chem , vol.18 , Issue.3 , pp. 1244-1251
    • Huang, L.1    Shi, A.2    He, F.3
  • 94
    • 84856914519 scopus 로고    scopus 로고
    • New tacrine-4-oxo-4H-chromene hybrids as multifunctional agents for the treatment of Alzheimer's disease, with cholinergic, antioxidant, and beta-amyloid-reducing properties [J]
    • 94 Fernandez-Bachiller, MI, Perez, C, Monjas, L, et al. New tacrine-4-oxo-4H-chromene hybrids as multifunctional agents for the treatment of Alzheimer's disease, with cholinergic, antioxidant, and beta-amyloid-reducing properties [J]. J Med Chem 55:3 (2012), 1303–1317.
    • (2012) J Med Chem , vol.55 , Issue.3 , pp. 1303-1317
    • Fernandez-Bachiller, M.I.1    Perez, C.2    Monjas, L.3
  • 95
    • 84867086604 scopus 로고    scopus 로고
    • Neuroprotective effect of α-mangostin and curcumin against iodoacetate-induced cell death [J]
    • 95 Reyes-Fermin, LM, Gonzalez-Reyes, S, Tarco-Alvarez, NG, et al. Neuroprotective effect of α-mangostin and curcumin against iodoacetate-induced cell death [J]. Nutr Neurosci 15:5 (2012), 34–41.
    • (2012) Nutr Neurosci , vol.15 , Issue.5 , pp. 34-41
    • Reyes-Fermin, L.M.1    Gonzalez-Reyes, S.2    Tarco-Alvarez, N.G.3
  • 96
    • 68549100003 scopus 로고    scopus 로고
    • ROS scavenging capacity and neuroprotective effect of α-mangostin against 3-nitropropionic acid in cerebellar granule neurons [J]
    • 96 Pedraza-Chaverri, J, Reyes-Fermin, LM, Nolasco-Amaya, EG, et al. ROS scavenging capacity and neuroprotective effect of α-mangostin against 3-nitropropionic acid in cerebellar granule neurons [J]. Exp Toxicol Pathol 61:5 (2009), 491–501.
    • (2009) Exp Toxicol Pathol , vol.61 , Issue.5 , pp. 491-501
    • Pedraza-Chaverri, J.1    Reyes-Fermin, L.M.2    Nolasco-Amaya, E.G.3
  • 97
    • 84867089914 scopus 로고    scopus 로고
    • α-Mangostin induces changes in glutathione levels associated with glutathione peroxidase activity in rat brain synaptosomes [J]
    • 97 Marquez-Valadez, B, Maldonado, PD, Galvan-Arzate, S, et al. α-Mangostin induces changes in glutathione levels associated with glutathione peroxidase activity in rat brain synaptosomes [J]. Nutr Neurosci 15:5 (2012), 13–19.
    • (2012) Nutr Neurosci , vol.15 , Issue.5 , pp. 13-19
    • Marquez-Valadez, B.1    Maldonado, P.D.2    Galvan-Arzate, S.3
  • 98
    • 84892456529 scopus 로고    scopus 로고
    • DNA protective effect of mangosteen xanthones: an in vitro study on possible mechanisms [J]
    • 98 Lin, J, Gao, Y, Li, H, et al. DNA protective effect of mangosteen xanthones: an in vitro study on possible mechanisms [J]. Adv Pharm Bull 4:2 (2014), 147–153.
    • (2014) Adv Pharm Bull , vol.4 , Issue.2 , pp. 147-153
    • Lin, J.1    Gao, Y.2    Li, H.3
  • 99
    • 84906735586 scopus 로고    scopus 로고
    • Prenylated xanthones from mangosteen as promising cholinesterase inhibitors and their molecular docking studies [J]
    • 99 Khaw, KY, Choi, SB, Tan, SC, et al. Prenylated xanthones from mangosteen as promising cholinesterase inhibitors and their molecular docking studies [J]. Phytomedicine 21:11 (2014), 1303–1309.
    • (2014) Phytomedicine , vol.21 , Issue.11 , pp. 1303-1309
    • Khaw, K.Y.1    Choi, S.B.2    Tan, S.C.3
  • 100
    • 84894205957 scopus 로고    scopus 로고
    • Rapid identification of cholinesterase inhibitors from the seedcases of mangosteen using an enzyme affinity assay [J]
    • 100 Ryu, HW, Oh, SR, Curtis-Long, MJ, et al. Rapid identification of cholinesterase inhibitors from the seedcases of mangosteen using an enzyme affinity assay [J]. J Agric Food Chem 62:6 (2014), 1338–1343.
    • (2014) J Agric Food Chem , vol.62 , Issue.6 , pp. 1338-1343
    • Ryu, H.W.1    Oh, S.R.2    Curtis-Long, M.J.3
  • 101
    • 84902002566 scopus 로고    scopus 로고
    • Neuroprotective effects of xanthone derivative of Garcinia mangostana against lead-induced acetylcholinesterase dysfunction and cognitive impairment [J]
    • 101 Phyu, MP, Tangpong, J, Neuroprotective effects of xanthone derivative of Garcinia mangostana against lead-induced acetylcholinesterase dysfunction and cognitive impairment [J]. Food Chem Toxicol 70 (2014), 151–156.
    • (2014) Food Chem Toxicol , vol.70 , pp. 151-156
    • Phyu, M.P.1    Tangpong, J.2
  • 102
    • 84855959508 scopus 로고    scopus 로고
    • α-Mangostin, a polyphenolic xanthone derivative from mangosteen, attenuates beta-amyloid oligomers-induced neurotoxicity by inhibiting amyloid aggregation [J]
    • 102 Wang, Y, Xia, Z, Xu, JR, et al. α-Mangostin, a polyphenolic xanthone derivative from mangosteen, attenuates beta-amyloid oligomers-induced neurotoxicity by inhibiting amyloid aggregation [J]. Neuropharmacology 62:2 (2012), 871–881.
    • (2012) Neuropharmacology , vol.62 , Issue.2 , pp. 871-881
    • Wang, Y.1    Xia, Z.2    Xu, J.R.3
  • 103
    • 33344463679 scopus 로고    scopus 로고
    • Common mechanisms of amyloid oligomer pathogenesis in degenerative disease [J]
    • 103 Glabe, CG, Common mechanisms of amyloid oligomer pathogenesis in degenerative disease [J]. Neurobiol Aging 27:4 (2006), 570–575.
    • (2006) Neurobiol Aging , vol.27 , Issue.4 , pp. 570-575
    • Glabe, C.G.1
  • 104
    • 0011162190 scopus 로고
    • Selective loss of central cholinergic neurons in Alzheimer's disease [J]
    • 104 Davies, P, Maloney, A, Selective loss of central cholinergic neurons in Alzheimer's disease [J]. The Lancet, 308(8000), 1976, 1403.
    • (1976) The Lancet , vol.308 , Issue.8000 , pp. 1403
    • Davies, P.1    Maloney, A.2
  • 105
    • 4043074138 scopus 로고    scopus 로고
    • Cholinesterase inhibitors: new roles and therapeutic alternatives [J]
    • 105 Giacobini, E, Cholinesterase inhibitors: new roles and therapeutic alternatives [J]. Pharmacol Res 50:4 (2004), 433–440.
    • (2004) Pharmacol Res , vol.50 , Issue.4 , pp. 433-440
    • Giacobini, E.1
  • 106
    • 84876682548 scopus 로고    scopus 로고
    • Synthesis and biological evaluation of 1, 3-dihydroxyxanthone mannich base derivatives as anticholinesterase agents [J]
    • 106 Qin, J, Lan, W, Liu, Z, et al. Synthesis and biological evaluation of 1, 3-dihydroxyxanthone mannich base derivatives as anticholinesterase agents [J]. Chem Cent J, 7(1), 2013, 78.
    • (2013) Chem Cent J , vol.7 , Issue.1 , pp. 78
    • Qin, J.1    Lan, W.2    Liu, Z.3
  • 107
    • 79955604149 scopus 로고    scopus 로고
    • New potent human acetylcholinesterase inhibitors in the tetracyclic triterpene series with inhibitory potency on amyloid beta aggregation [J]
    • 107 Rouleau, J, Iorga, BI, Guillou, C, New potent human acetylcholinesterase inhibitors in the tetracyclic triterpene series with inhibitory potency on amyloid beta aggregation [J]. Eur J Med Chem 46:6 (2011), 2193–2205.
    • (2011) Eur J Med Chem , vol.46 , Issue.6 , pp. 2193-2205
    • Rouleau, J.1    Iorga, B.I.2    Guillou, C.3
  • 108
    • 84940879852 scopus 로고    scopus 로고
    • Identification of hepatoprotective xanthones from the pericarps of Garcinia mangostana, guided with tert-butyl hydroperoxide induced oxidative injury in HL-7702 cells [J]
    • 108 Wang, QL, Yang, Ye, Wang, YT, et al. Identification of hepatoprotective xanthones from the pericarps of Garcinia mangostana, guided with tert-butyl hydroperoxide induced oxidative injury in HL-7702 cells [J]. Food & Funct 6:9 (2015), 3013–3021.
    • (2015) Food & Funct , vol.6 , Issue.9 , pp. 3013-3021
    • Wang, Q.L.1    Yang, Y.2    Wang, Y.T.3
  • 109
    • 84942856044 scopus 로고    scopus 로고
    • α-Mangostin regulates hepatic steatosis and obesity through SirT1-AMPK and PPARγ pathways in high-fat diet-induced obese mice [J]
    • 109 Choi, YH, Bae, JK, Chae, HS, et al. α-Mangostin regulates hepatic steatosis and obesity through SirT1-AMPK and PPARγ pathways in high-fat diet-induced obese mice [J]. J Agric Food Chem 63:38 (2015), 8399–8406.
    • (2015) J Agric Food Chem , vol.63 , Issue.38 , pp. 8399-8406
    • Choi, Y.H.1    Bae, J.K.2    Chae, H.S.3
  • 110
    • 84927127664 scopus 로고    scopus 로고
    • α-Mangostin improves glucose uptake and inhibits adipocytes differentiation in 3T3-L1 cells via PPARγ, GLUT4, and leptin expressions [J]
    • 110 Taher, Muhammad, Amiroudine, MZ AM, Tengku Zakaria, TM FS, et al. α-Mangostin improves glucose uptake and inhibits adipocytes differentiation in 3T3-L1 cells via PPARγ, GLUT4, and leptin expressions [J]. Evid Based Complement Alternat Med, 2015, 2015, 740238.
    • (2015) Evid Based Complement Alternat Med , vol.2015 , pp. 740238
    • Taher, M.1    Amiroudine, M.A.2    Tengku Zakaria, T.F.3
  • 111
    • 84881587908 scopus 로고    scopus 로고
    • Biological activities and bioavailability of mangosteen xanthones: a critical review of the current evidence [J]
    • 111 Gutierrez-Orozco, F, Failla, ML, Biological activities and bioavailability of mangosteen xanthones: a critical review of the current evidence [J]. Nutrients 5:8 (2013), 3163–3183.
    • (2013) Nutrients , vol.5 , Issue.8 , pp. 3163-3183
    • Gutierrez-Orozco, F.1    Failla, M.L.2
  • 112
    • 77954062148 scopus 로고    scopus 로고
    • Acute and repeated dose 28-day oral toxicity study of Garcinia mangostana Linn. rind extract [J]
    • 112 Jujun, P, Pootakham, K, Pongpaibul, Y, et al. Acute and repeated dose 28-day oral toxicity study of Garcinia mangostana Linn. rind extract [J]. CMU J Nat Sci 7 (2008), 199–208.
    • (2008) CMU J Nat Sci , vol.7 , pp. 199-208
    • Jujun, P.1    Pootakham, K.2    Pongpaibul, Y.3
  • 113
    • 84906505451 scopus 로고    scopus 로고
    • Antimalarial activity and toxicity of Garcinia mangostana Linn. [J]
    • 113 Bunyong, R, Chaijaroenkul, W, Plengsuriyakarn, T, et al. Antimalarial activity and toxicity of Garcinia mangostana Linn. [J]. Asian Pac J Trop Med 7:9 (2014), 693–698.
    • (2014) Asian Pac J Trop Med , vol.7 , Issue.9 , pp. 693-698
    • Bunyong, R.1    Chaijaroenkul, W.2    Plengsuriyakarn, T.3
  • 114
    • 77954067920 scopus 로고    scopus 로고
    • Acute and subchronic toxicity evaluation of the hydroethanolic extract of mangosteen pericarp [J]
    • 114 Hutadilok-Towatana, N, Reanmongkol, W, Wattanapiromsakul, C, et al. Acute and subchronic toxicity evaluation of the hydroethanolic extract of mangosteen pericarp [J]. J Med Plant Res 4 (2010), 969–974.
    • (2010) J Med Plant Res , vol.4 , pp. 969-974
    • Hutadilok-Towatana, N.1    Reanmongkol, W.2    Wattanapiromsakul, C.3
  • 115
    • 84920088151 scopus 로고    scopus 로고
    • α-Mangostin from Cratoxylum arborescens: an in vitro and in vivo toxicological evaluation [J]
    • 115 Ibrahim, MY, Hashim, NM, Mohan, S, et al. α-Mangostin from Cratoxylum arborescens: an in vitro and in vivo toxicological evaluation [J]. Arab J Chem 8:1 (2015), 129–137.
    • (2015) Arab J Chem , vol.8 , Issue.1 , pp. 129-137
    • Ibrahim, M.Y.1    Hashim, N.M.2    Mohan, S.3
  • 116
    • 84969863661 scopus 로고    scopus 로고
    • Daily consumption of a mangosteen-based drink improves in vivo antioxidant and anti-inflammatory biomarkers in healthy adults: a randomized, double-blind, placebo-controlled clinical trial [J]
    • 116 Xie, Z, Sintara, M, Chang, T, et al. Daily consumption of a mangosteen-based drink improves in vivo antioxidant and anti-inflammatory biomarkers in healthy adults: a randomized, double-blind, placebo-controlled clinical trial [J]. Food Sci Nutr 3:4 (2015), 342–348.
    • (2015) Food Sci Nutr , vol.3 , Issue.4 , pp. 342-348
    • Xie, Z.1    Sintara, M.2    Chang, T.3
  • 117
    • 84965046600 scopus 로고    scopus 로고
    • Functional beverage of Garcinia mangostana (mangosteen) enhances plasma antioxidant capacity in healthy adults [J]
    • 117 Xie, Z, Sintara, M, Chang, T, et al. Functional beverage of Garcinia mangostana (mangosteen) enhances plasma antioxidant capacity in healthy adults [J]. Food Sci Nutr 3:1 (2015), 32–38.
    • (2015) Food Sci Nutr , vol.3 , Issue.1 , pp. 32-38
    • Xie, Z.1    Sintara, M.2    Chang, T.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.