DNA protective effect of mangosteen xanthones: An in vitro study on possible mechanisms

Advanced Pharmaceutical Bulletin

Volumn 4, Issue 2, 2014, Pages 147-153

  Lin, Jing ^a   Gao, Yaoxiang ^a   Li, Haiming ^a   Zhang, Lulu ^a   Li, Xican ^a  

^a GUANGZHOU UNIVERSITY OF CHINESE MEDICINE   (China)

Author keywords

Antioxidant; DNA oxidative damage; Hydroxyl induced; Mangosteen shell; Mechanism; Xanthones

Indexed keywords

ANTIOXIDANT; GAMMA MANGOSTIN; IRON; MANGOSTEEN EXTRACT; METHANOL; PLANT EXTRACT; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG; XANTHONE DERIVATIVE;

ABTS RADICAL SCAVENGING ASSAY; ANTIOXIDANT ACTIVITY; ARTICLE; CHELATION; CONTROLLED STUDY; DNA DAMAGE; DNA REPAIR; DOSE RESPONSE; DPPH RADICAL SCAVENGING ASSAY; DRUG ISOLATION; DRUG MECHANISM; DRUG STRUCTURE; ELECTRON TRANSPORT; GARCINIA MANGOSTANA; HYDROXYL RADICAL SCAVENGING ASSAY; IC 50; IN VITRO STUDY; MANGOSTEEN; OXIDATIVE STRESS; PROTECTION; PROTON TRANSPORT; REDUCTION; SOLVENT EXTRACTION; STRUCTURE ANALYSIS;

EID: 84892456529     PISSN: 22285881     EISSN: 22517308     Source Type: Journal    
DOI: 10.5681/apb.2014.022     Document Type: Article

References (21)

1. Yu LM, Zhao M, Yang B, Zhao QZ, Jiang Y. Phenolics from hull of Garcinia mangostana fruit and their antioxidant activities. Food Chem 2007;104:176-81.
2. Zheng R, Wang C, Lin C, Shi Y, Li J, Zhao C, et al. The earliest stage of carcinogenesis blocked by the fast repair of DNA transient damage. Acta Biophys Sinica 2012;28(3):185-99.
3. Tanaka R. Inhibitory effects of xanthone on paraquat- and NaNO(2)-induced genotoxicity in cultured cells. J Toxicol Sci 2007;32(5):571-4.
4. Li X, Wu X, Huang L. Correlation between antioxidant activities and phenolic contents of radix Angelicae Sinensis (Danggui). Molecules 2009;14(12):5349-61.
5. Li X, Mai W, Wang L, Han W. A hydroxyl-scavenging assay based on DNA damage in vitro. Anal Biochem 2013;438(1):29-31.
6. Li X. Solvent effects and improvements in the deoxyribose degradation assay for hydroxyl radical-scavenging. Food Chem 2013;141(3):2083-8.
7. Li X, Lin J, Gao Y, Han W, Chen D. Antioxidant activity and mechanism of Rhizoma Cimicifugae. Chem Cent J 2012;6(1):140.
8. Li X, Chen C. Systematic evaluation on antioxidant of magnolol in vitro. Int Res J Pure Appl Chem 2012;2(1):68-76.
9. Gao Y, Hu Q, Li X. Chemical composition and antioxidant activity of essential oil from Syzygium samarangense (BL.) Merr.et Perry flower-bud. Spatula DD 2012;2(1):23-33.
10. Oyaizu M. Studies on product of browning reaction prepared from glucoseamine. Jpn J Nutr 1986;44(6):307-15.
11. Wang L, Li X. Antioxidant Activity of Durian (Durio zibethinus Murr.) Shell in vitro. Asian J Pharm Biol Res 2011;1(4):542-51.
12. Chaivisuthangkura A, Malaikaew Y, Chaovanalikit A, Jaratrungtawee A, Panseeta P, Ratananukul P, et al. Prenylated xanthone composition of Garcinia mangostana (Mangosteen) Fruit Hull. Chromatographia 2009;69:315-8.
13. Obolskiy D, Pischel I, Siriwatanametanon N, Heinrich M. Garcinia mangostana L.: a phytochemical and pharmacological review. Phytother Res 2009;23(8):1047-65.
14. Li X, Chen W, Chen D. Protective effect against hydroxyl-induced DNA damage and antioxidant activity of Radix Glycyrrhizae (Liquorice Root). Adv Pharm Bull 2013;3(1):167-73.
15. Zheng R, Huang Z. Free radical biology. Beijing: Higher Education Press; 2007.
16. Cerutti PA. Prooxidant states and tumor promotion. Science 1985;227(4685):375-81.
17. Bondet V, Williams W, Berset C. Kinetics and mechanisms of antioxidant activity using the DPPH• free radical method. LWT-Food Sci Technol 1997;30(6):609-15.
18. Dimitrios IT, Vassiliki O. The contribution of flavonoid C-ring on the DPPH free radical scavenging efficiency. A kinetic approach for the 3', 4'-hydroxy substituted members. Innov Food Sci Emerg Technol 2006;7(1-2):140-6.
19. Khanduja KL, Bhardwaj A. Stable free radical scavenging and antiperoxidative properties of resveratrol compared in vitro with some other bioflavonoids. Indian J Biochem Biophys 2003;40(6):416-22.
20. Zhang D, Liu Y, Chu L, Wei Y, Wang D, Cai S, et al. Relationship Between the Structures of Flavonoids and Oxygen Radical Absorbance Capacity Values: A Quantum Chemical Analysis. J Phys Chem A 2013;117(8):1784-94.
21. Aliaga C, Lissi EA. Reaction of 2, 2'-azinobis (3-ethylbenzothiazoline-6-sulfonic acid (ABTS) derived radicals with hydroperoxides.Kinetics and mechanism. Int J Chem Kine1998;30(8):565-70.