α-Mangostin extracted from the pericarp of the mangosteen (Garcinia mangostana Linn) reduces tumor growth and lymph node metastasis in an immunocompetent xenograft model of metastatic mammary cancer carrying a p53 mutation

BMC Medicine

Volumn 9, Issue , 2011, Pages

  Shibata, Masa Aki ^a,b   Iinuma, Munekazu ^c   Morimoto, Junji ^b   Kurose, Hitomi ^b   Akamatsu, Kanako ^d   Okuno, Yasushi ^d   Akao, Yukihiro ^e   Otsuki, Yoshinori ^b  

^a OSAKA HEALTH SCIENCE UNIVERSITY   (Japan)

^b OSAKA MEDICAL COLLEGE   (Japan)

^c GIFU PHARMACEUTICAL UNIVERSITY   (Japan)

^d KYOTO UNIVERSITY   (Japan)

^e GIFU UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA MANGOSTIN; BETA ACTIN; CASPASE 3; CASPASE 9; GARCINIA MANGOSTANA EXTRACT; PLANT EXTRACT; PROTEIN BID; PROTEIN KINASE B; PROTEIN P53; SERINE; THREONINE; UNCLASSIFIED DRUG; ANTINEOPLASTIC AGENT; MANGOSTIN; XANTHONE DERIVATIVE;

ANGIOGENESIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; BREAST CANCER; CANCER CELL CULTURE; CANCER INHIBITION; CARCINOGENESIS; CELL CYCLE ARREST; CELL CYCLE G1 PHASE; CELL CYCLE S PHASE; CELL PROLIFERATION; CONTROLLED STUDY; DRUG MECHANISM; ENZYME PHOSPHORYLATION; FEMALE; GARCINIA MANGOSTANA; GENE MUTATION; HISTOPATHOLOGY; HUMAN; HUMAN CELL; IMMUNOCOMPETENCE; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; LYMPH NODE METASTASIS; LYMPH VESSEL; MANGOSTEEN; METASTASIS INHIBITION; MITOCHONDRION; MOUSE; NONHUMAN; PERICARP; PROGNOSIS; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; SURVIVAL RATE; TUMOR VOLUME; TUMOR XENOGRAFT; ANIMAL; BAGG ALBINO MOUSE; CHEMISTRY; EXPERIMENTAL NEOPLASM; GENETICS; ISOLATION AND PURIFICATION; LYMPH NODE; METASTASIS; MUTATION; NEOPLASM; PATHOLOGY; TREATMENT OUTCOME; XENOGRAFT;

ANIMALS; ANTINEOPLASTIC AGENTS; FEMALE; GARCINIA MANGOSTANA; HUMANS; LYMPH NODES; MAMMARY NEOPLASMS, ANIMAL; MAMMARY NEOPLASMS, EXPERIMENTAL; MICE; MICE, INBRED BALB C; MUTATION; NEOPLASM METASTASIS; NEOPLASMS; TRANSPLANTATION, HETEROLOGOUS; TREATMENT OUTCOME; TUMOR SUPPRESSOR PROTEIN P53; XANTHONES;

EID: 79957877575     PISSN: None     EISSN: 17417015     Source Type: Journal    
DOI: 10.1186/1741-7015-9-69     Document Type: Article

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