α -mangostin suppresses the viability and epithelial-mesenchymal transition of pancreatic cancer cells by downregulating the PI3K/Akt pathway

BioMed Research International

Volumn 2014, Issue , 2014, Pages

  Xu, Qinhong ^a   Ma, Jiguang ^a   Lei, Jianjun ^a   Duan, Wanxing ^a   Sheng, Liang ^a   Chen, Xin ^a   Hu, Ang ^a   Wang, Zheng ^a   Wu, Zheng ^a   Wu, Erxi ^b   Ma, Qingyong ^a   Li, Xuqi ^a  

^a XI'AN JIAOTONG UNIVERSITY   (China)

^b NORTH DAKOTA STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA MANGOSTIN; ANTINEOPLASTIC AGENT; CYCLIN D1; GELATINASE A; GELATINASE B; NATURAL PRODUCT; NERVE CELL ADHESION MOLECULE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; UNCLASSIFIED DRUG; UVOMORULIN; VIMENTIN; MANGOSTIN; XANTHONE DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CANCER CELL; CANCER INHIBITION; CELL CYCLE ARREST; CELL CYCLE G1 PHASE; CELL INVASION; CELL INVASION ASSAY; CELL MIGRATION; CELL VIABILITY; CONTROLLED STUDY; DOWN REGULATION; DRUG MECHANISM; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; EPITHELIAL MESENCHYMAL TRANSITION; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MALE; MATRIGEL INVASION ASSAY; MOUSE; MOUSE MODEL; NONHUMAN; PANCREAS CANCER; PANCREATIC CANCER CELL LINE; PROTEIN EXPRESSION; REDUCTION; SIGNAL TRANSDUCTION; TRANSWELL INVASION ASSAY; TUMOR CELL INOCULATION; TUMOR XENOGRAFT; ANIMAL; BAGG ALBINO MOUSE; CELL CYCLE CHECKPOINT; CELL CYCLE G0 PHASE; CELL MOTION; CELL PROLIFERATION; CELL SURVIVAL; DRUG EFFECTS; ENZYMOLOGY; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; NUDE MOUSE; PANCREAS TUMOR; PATHOLOGY; TUMOR CELL LINE; TUMOR INVASION;

ANIMALS; APOPTOSIS; CELL CYCLE CHECKPOINTS; CELL LINE, TUMOR; CELL MOVEMENT; CELL PROLIFERATION; CELL SURVIVAL; DOWN-REGULATION; EPITHELIAL-MESENCHYMAL TRANSITION; G0 PHASE; G1 PHASE; GENE EXPRESSION REGULATION, NEOPLASTIC; MALE; MICE, INBRED BALB C; MICE, NUDE; NEOPLASM INVASIVENESS; PANCREATIC NEOPLASMS; PHOSPHATIDYLINOSITOL 3-KINASES; PROTO-ONCOGENE PROTEINS C-AKT; SIGNAL TRANSDUCTION; XANTHONES;

EID: 84899995986     PISSN: 23146133     EISSN: 23146141     Source Type: Journal    
DOI: 10.1155/2014/546353     Document Type: Article

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