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Volumn 57, Issue 2, 2013, Pages 203-211

Anti-tumorigenicity of dietary α-mangostin in an HT-29 colon cell xenograft model and the tissue distribution of xanthones and their phase II metabolites

Author keywords

Mangostin; Catenin protein; BcL 2 protein; Tumor mass; Xenograft

Indexed keywords

ANTINEOPLASTIC AGENT; BETA CATENIN; BIOLOGICAL MARKER; MANGOSTIN; PROTEIN BCL 2; XANTHONE; XANTHONE DERIVATIVE;

EID: 84872793155     PISSN: 16134125     EISSN: 16134133     Source Type: Journal    
DOI: 10.1002/mnfr.201200539     Document Type: Article
Times cited : (65)

References (38)
  • 2
    • 0033972965 scopus 로고    scopus 로고
    • Chronic inflammatory bowel disease and cancer
    • Pohl, C., Hombach, A., Kruis, W., Chronic inflammatory bowel disease and cancer. Hepato-gastroenterology 2000, 47, 57-70
    • (2000) Hepato-gastroenterology , vol.47 , pp. 57-70
    • Pohl, C.1    Hombach, A.2    Kruis, W.3
  • 3
    • 48649095089 scopus 로고    scopus 로고
    • Cancer chemoprevention and chemotherapy: dietary polyphenols and signaling pathways
    • Ramos, S., Cancer chemoprevention and chemotherapy: dietary polyphenols and signaling pathways. Mol. Nutr. Food Res. 2008, 52, 507-526.
    • (2008) Mol. Nutr. Food Res. , vol.52 , pp. 507-526
    • Ramos, S.1
  • 4
    • 84862070400 scopus 로고    scopus 로고
    • Getting ahead of the curve: phytochemicals
    • Sloan, E. W., Getting ahead of the curve: phytochemicals. Nutraceutical World 2010, 13, 16-17.
    • (2010) Nutraceutical World , vol.13 , pp. 16-17
    • Sloan, E.W.1
  • 6
    • 57249112596 scopus 로고    scopus 로고
    • Structural characterization, biological effects, and synthetic studies on xanthones from mangosteen (Garcinia mangostana), a popular botanical dietary supplement
    • Chin, Y. W., Kinghorn, A. D., Structural characterization, biological effects, and synthetic studies on xanthones from mangosteen (Garcinia mangostana), a popular botanical dietary supplement. Mini-Rev. Organ. Chem. 2008, 5, 355-364.
    • (2008) Mini-Rev. Organ. Chem. , vol.5 , pp. 355-364
    • Chin, Y.W.1    Kinghorn, A.D.2
  • 7
    • 66749135984 scopus 로고    scopus 로고
    • Bioaccessibility, biotransformation and transport of α-mangostin from Garcina mangostana (mangosteen) using simulated digestion and Caco-2 human intestinal cells
    • Bumrungpert, A., Kalpravidh, R. W., Suksamrarn, S., Chaivisuthangkura, A. et al., Bioaccessibility, biotransformation and transport of α-mangostin from Garcina mangostana (mangosteen) using simulated digestion and Caco-2 human intestinal cells. Mol. Nutr. Food Res. 2009, 53, S54-S61.
    • (2009) Mol. Nutr. Food Res. , vol.53
    • Bumrungpert, A.1    Kalpravidh, R.W.2    Suksamrarn, S.3    Chaivisuthangkura, A.4
  • 8
    • 84861142005 scopus 로고    scopus 로고
    • Xanthones in mangosteen juice are absorbed and partially conjugated by healthy adults
    • Chitchumroonchokchai, C., Riedl, K. M., Suksumrarn, S., Clinton, S. K. et al., Xanthones in mangosteen juice are absorbed and partially conjugated by healthy adults. J. Nutr. 2012, 142, 675-680.
    • (2012) J. Nutr. , vol.142 , pp. 675-680
    • Chitchumroonchokchai, C.1    Riedl, K.M.2    Suksumrarn, S.3    Clinton, S.K.4
  • 9
    • 69249184433 scopus 로고    scopus 로고
    • Panaxanthone isolated from pericarp of Garcinia mangostana L. suppresses tumor growth and metastasis of a mouse model of mammary cancer
    • Doi, H., Shibata, M., Shibata, E., Morimoto, J. et al., Panaxanthone isolated from pericarp of Garcinia mangostana L. suppresses tumor growth and metastasis of a mouse model of mammary cancer. Anticancer Res. 2009, 29, 2485-2496.
    • (2009) Anticancer Res. , vol.29 , pp. 2485-2496
    • Doi, H.1    Shibata, M.2    Shibata, E.3    Morimoto, J.4
  • 10
    • 16644370363 scopus 로고    scopus 로고
    • Inhibitory effects of crude α-mangostin, a xanthone derivative, on two different categories of colon preneoplastic lesions induced by 1,2-dimethylhydrazine in the rat
    • Nabandith, V., Suzuki, M., Morika, T., Kaneshiro, T. et al., Inhibitory effects of crude α-mangostin, a xanthone derivative, on two different categories of colon preneoplastic lesions induced by 1, 2-dimethylhydrazine in the rat. Asian Pac. J. Cancer Prev. 2004, 5, 433-438.
    • (2004) Asian Pac. J. Cancer Prev. , vol.5 , pp. 433-438
    • Nabandith, V.1    Suzuki, M.2    Morika, T.3    Kaneshiro, T.4
  • 12
    • 33645765822 scopus 로고    scopus 로고
    • Antioxidant xanthones from the pericarp of Garcinia mangostana (mangosteen)
    • Jung, H. A., Su, B. N., Keller, W. J., Mehta, R. G. et al., Antioxidant xanthones from the pericarp of Garcinia mangostana (mangosteen). J. Agric. Food Chem. 2006, 54, 2077-2082.
    • (2006) J. Agric. Food Chem. , vol.54 , pp. 2077-2082
    • Jung, H.A.1    Su, B.N.2    Keller, W.J.3    Mehta, R.G.4
  • 13
    • 0027487229 scopus 로고
    • AIN-93 purified diet for laboratory rodents: final report of the American Institute of Nutrition ad hoc writing committee on the reformulation of the AIN-76A rodent diet
    • Reeves, P. G., Nielsen, F. H., Fahey, G. C., AIN-93 purified diet for laboratory rodents: final report of the American Institute of Nutrition ad hoc writing committee on the reformulation of the AIN-76A rodent diet. J. Nutr. 1993, 123, 1939-1951.
    • (1993) J. Nutr. , vol.123 , pp. 1939-1951
    • Reeves, P.G.1    Nielsen, F.H.2    Fahey, G.C.3
  • 14
    • 0031913265 scopus 로고    scopus 로고
    • Matrigel augments xenograft transplantation of meningioma cells into athymic mice
    • Jensen, R. L., Leppla, D., Rokosz, N., Wurster, R. D., Matrigel augments xenograft transplantation of meningioma cells into athymic mice. Neurosurgery 1998, 42, 130-136.
    • (1998) Neurosurgery , vol.42 , pp. 130-136
    • Jensen, R.L.1    Leppla, D.2    Rokosz, N.3    Wurster, R.D.4
  • 15
    • 34248589538 scopus 로고    scopus 로고
    • Specific growth rate versus doubling time for quantitative characterization of tumor growth rate
    • Mehrara, E., Forssell-Aronsson, E., Ahlman, H., Bernhardt, P., Specific growth rate versus doubling time for quantitative characterization of tumor growth rate. Cancer Res. 2007, 67, 3970-3975.
    • (2007) Cancer Res. , vol.67 , pp. 3970-3975
    • Mehrara, E.1    Forssell-Aronsson, E.2    Ahlman, H.3    Bernhardt, P.4
  • 16
    • 34147147914 scopus 로고    scopus 로고
    • Isoflavonoid glucosides are deconjugated and absorbed in the small intestine of human subjects with ileostomies
    • Walsh, K. R., Haak, S. J., Bohn, T., Tian, Q. et al., Isoflavonoid glucosides are deconjugated and absorbed in the small intestine of human subjects with ileostomies. Am. J. Clin. Nutr. 2007, 85, 1050-1056.
    • (2007) Am. J. Clin. Nutr. , vol.85 , pp. 1050-1056
    • Walsh, K.R.1    Haak, S.J.2    Bohn, T.3    Tian, Q.4
  • 17
    • 0021061819 scopus 로고
    • Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays
    • Mosmann, T., Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J. Immunol. Methods 1983, 65, 55-63.
    • (1983) J. Immunol. Methods , vol.65 , pp. 55-63
    • Mosmann, T.1
  • 18
    • 35848936502 scopus 로고    scopus 로고
    • Dietary modulation of colon cancer risk
    • Kim, Y. S., Milner, J., Dietary modulation of colon cancer risk. J. Nutr. 2007, 137, 2576S-2579S.
    • (2007) J. Nutr. , vol.137
    • Kim, Y.S.1    Milner, J.2
  • 19
    • 80053999477 scopus 로고    scopus 로고
    • Xanthones from mangosteen as natural chemopreventive agents: potential anticancer drugs
    • Shan, T., Ma, Q., Guo, K., Liu, J. et al., Xanthones from mangosteen as natural chemopreventive agents: potential anticancer drugs. Curr. Mol. Med. 2011, 11, 666-677.
    • (2011) Curr. Mol. Med. , vol.11 , pp. 666-677
    • Shan, T.1    Ma, Q.2    Guo, K.3    Liu, J.4
  • 20
    • 84863044558 scopus 로고    scopus 로고
    • α-Mangostin, a xanthone from mangosteen fruit, promotes cell cycle arrest in prostate cancer and decreases xenograft tumor growth
    • Johnson, J. J., Petiwala, S. M., Syed, D. N., Rasmussen, J. T. et al., α-Mangostin, a xanthone from mangosteen fruit, promotes cell cycle arrest in prostate cancer and decreases xenograft tumor growth. Carcinogenesis 2012, 33, 413-419.
    • (2012) Carcinogenesis , vol.33 , pp. 413-419
    • Johnson, J.J.1    Petiwala, S.M.2    Syed, D.N.3    Rasmussen, J.T.4
  • 21
    • 79957877575 scopus 로고    scopus 로고
    • α-Mangostin extracted from the pericarp of the mangosteen (Garcinia mangostana Linn) reduces tumor growth and lymph node metastasis in an immunocompetent xenograft model of metastatic mammary cancer carrying a p53 mutation
    • Shibata, M. A., Linuma, M., Morimoto, J., Kurose, H. et al., α-Mangostin extracted from the pericarp of the mangosteen (Garcinia mangostana Linn) reduces tumor growth and lymph node metastasis in an immunocompetent xenograft model of metastatic mammary cancer carrying a p53 mutation. BMC Med. 2011, 9, 1-18.
    • (2011) BMC Med. , vol.9 , pp. 1-18
    • Shibata, M.A.1    Linuma, M.2    Morimoto, J.3    Kurose, H.4
  • 22
    • 79955932364 scopus 로고    scopus 로고
    • Potential of xanthones from tropical fruit mangosteen as anti-cancer agents: capase-dependent apoptosis induction in vitro and in mice
    • Watanapokasin, R., Jarinthanan, F., Jerusalmi, A., Suksanrarn, S. et al., Potential of xanthones from tropical fruit mangosteen as anti-cancer agents: capase-dependent apoptosis induction in vitro and in mice. Appl. Biochem. Biotechnol. 2011, 17, 2086-2095.
    • (2011) Appl. Biochem. Biotechnol. , vol.17 , pp. 2086-2095
    • Watanapokasin, R.1    Jarinthanan, F.2    Jerusalmi, A.3    Suksanrarn, S.4
  • 23
    • 0036973288 scopus 로고    scopus 로고
    • Xanthones as inhibitors of growth of human cancer cell lines and their effects on the proliferation of human lymphocytes in vitro
    • Pedro, M., Cerqueira, F., Sousa, M. E., Nascimento, M. S. et al., Xanthones as inhibitors of growth of human cancer cell lines and their effects on the proliferation of human lymphocytes in vitro. Bioorg. Med. Chem. 2002, 10, 3725-3730.
    • (2002) Bioorg. Med. Chem. , vol.10 , pp. 3725-3730
    • Pedro, M.1    Cerqueira, F.2    Sousa, M.E.3    Nascimento, M.S.4
  • 24
    • 73349098430 scopus 로고    scopus 로고
    • Cytotoxic xanthone constituents of the stem bark of Garcinia mangostana (mangosteen)
    • Han, A. R., Kim, J. A., Lantvit, D. D., Kardono, L. S. et al., Cytotoxic xanthone constituents of the stem bark of Garcinia mangostana (mangosteen). J. Nat. Prod. 2009, 72, 2028-2031.
    • (2009) J. Nat. Prod , vol.72 , pp. 2028-2031
    • Han, A.R.1    Kim, J.A.2    Lantvit, D.D.3    Kardono, L.S.4
  • 25
    • 25844498582 scopus 로고    scopus 로고
    • Xanthones induce cell-cycle arrest and apoptosis in human colon cancer DLD-1 cells
    • Matsumoto, K., Akao, Y., Ohguchi, K., Ito, T. et al., Xanthones induce cell-cycle arrest and apoptosis in human colon cancer DLD-1 cells. Bioorg. Med. Chem. 2005, 13, 6064-6069.
    • (2005) Bioorg. Med. Chem. , vol.13 , pp. 6064-6069
    • Matsumoto, K.1    Akao, Y.2    Ohguchi, K.3    Ito, T.4
  • 26
    • 34250705898 scopus 로고    scopus 로고
    • Characterized mechanism of α-mangostin-induced cell death: capase-independent apoptosis with release of endo-nuclease-G from mitochondria and increased miR-143 expression in human colorectal cancer DLD-1 cells
    • Nakagawa, Y., Iinuma, M., Naoe, T., Nozawa, Y. et al., Characterized mechanism of α-mangostin-induced cell death: capase-independent apoptosis with release of endo-nuclease-G from mitochondria and increased miR-143 expression in human colorectal cancer DLD-1 cells. Bioorg. Med. Chem. 2007, 15, 5620-5628.
    • (2007) Bioorg. Med. Chem. , vol.15 , pp. 5620-5628
    • Nakagawa, Y.1    Iinuma, M.2    Naoe, T.3    Nozawa, Y.4
  • 27
    • 78650663571 scopus 로고    scopus 로고
    • Apoptotic effects of γ-mangostin from the fruit hull of Garcinia mangostana on human malignant glioma cells
    • Chang, H. F., Huang, W. T., Chen, H. J., Yang, L. L., Apoptotic effects of γ-mangostin from the fruit hull of Garcinia mangostana on human malignant glioma cells. Molecules 2010, 15, 8953-8966.
    • (2010) Molecules , vol.15 , pp. 8953-8966
    • Chang, H.F.1    Huang, W.T.2    Chen, H.J.3    Yang, L.L.4
  • 28
    • 64549092413 scopus 로고    scopus 로고
    • α-Mangostin suppresses PC-3 human prostate carcinoma cell metastasis by inhibiting matrix metalloproteinase-2/9 and urokinase- plasminogen expression through the JNK signaling pathway
    • Hung, S. H., Shen, K. H., Wu, C. H., Liu, C. L. et al., α-Mangostin suppresses PC-3 human prostate carcinoma cell metastasis by inhibiting matrix metalloproteinase-2/9 and urokinase- plasminogen expression through the JNK signaling pathway. J. Agric. Food Chem. 2009, 57, 1291-1298.
    • (2009) J. Agric. Food Chem. , vol.57 , pp. 1291-1298
    • Hung, S.H.1    Shen, K.H.2    Wu, C.H.3    Liu, C.L.4
  • 29
    • 77955665296 scopus 로고    scopus 로고
    • α-Mangostin suppresses phorbol 12-myristate 13-acetate-induced MMP-2/MMP-9 expression via αvβ-integrin/FAK/ERK and NFκB signaling pathway in human lung adenocarcinoma A549 cells
    • Shi, Y. W., Chien, S. T., Chen, P. S., Lee, J. H. et al., α-Mangostin suppresses phorbol 12-myristate 13-acetate-induced MMP-2/MMP-9 expression via αvβ-integrin/FAK/ERK and NFκB signaling pathway in human lung adenocarcinoma A549 cells. Cell Biochem. Biophys. 2010, 58, 31-44.
    • (2010) Cell Biochem. Biophys. , vol.58 , pp. 31-44
    • Shi, Y.W.1    Chien, S.T.2    Chen, P.S.3    Lee, J.H.4
  • 30
    • 79957964309 scopus 로고    scopus 로고
    • α-Mangostin induces apoptosis in human chondrosarcoma cells through down regulation of ERK/JNK and Akt signaling pathway
    • Krajarng, A., Nakamura, Y., Suksumrarn, S., Watanapokasin, R., α-Mangostin induces apoptosis in human chondrosarcoma cells through down regulation of ERK/JNK and Akt signaling pathway. J. Agric. Food Chem. 2011, 59, 5746-5754.
    • (2011) J. Agric. Food Chem. , vol.59 , pp. 5746-5754
    • Krajarng, A.1    Nakamura, Y.2    Suksumrarn, S.3    Watanapokasin, R.4
  • 31
    • 80051791437 scopus 로고    scopus 로고
    • α- and γ-mangostin inhibit proliferation of colon cancer cells via β-catenin gene regulation in Wnt/cGMP signaling
    • Yoo, J. H., Kang, K., Jho, E. H., Chin, Y. W. et al., α- and γ-mangostin inhibit proliferation of colon cancer cells via β-catenin gene regulation in Wnt/cGMP signaling. Food Chem. 2011, 129, 1550-1566.
    • (2011) Food Chem. , vol.129 , pp. 1550-1566
    • Yoo, J.H.1    Kang, K.2    Jho, E.H.3    Chin, Y.W.4
  • 32
    • 70349918140 scopus 로고    scopus 로고
    • Bioavailability and antioxidant activity of a xanthone-rich mangosteen (Garcinia mangostana) product in humans
    • Kondo, M., Zhang, L., Ji, H., Kou, Y. et al., Bioavailability and antioxidant activity of a xanthone-rich mangosteen (Garcinia mangostana) product in humans. J. Agric. Food Chem. 2009, 57, 8788-8792.
    • (2009) J. Agric. Food Chem. , vol.57 , pp. 8788-8792
    • Kondo, M.1    Zhang, L.2    Ji, H.3    Kou, Y.4
  • 33
    • 79957830018 scopus 로고    scopus 로고
    • Pharmacokinetics of α-mangostin in rats after intravenous and oral application
    • Li, L., Brunner, I., Han, A., Hamburger, M. et al., Pharmacokinetics of α-mangostin in rats after intravenous and oral application. Mol. Nutr. Food Res. 2011, 55, 1-8.
    • (2011) Mol. Nutr. Food Res. , vol.55 , pp. 1-8
    • Li, L.1    Brunner, I.2    Han, A.3    Hamburger, M.4
  • 34
    • 67649968264 scopus 로고    scopus 로고
    • The bioactivity of dietary anthocyanins is likely to be mediated by their degradation products
    • Kay, C. D., Kroon, P. A., Cassidy, A., The bioactivity of dietary anthocyanins is likely to be mediated by their degradation products. Mol. Nutr. Food Res. 2009, 53, S92-S101.
    • (2009) Mol. Nutr. Food Res. , vol.53
    • Kay, C.D.1    Kroon, P.A.2    Cassidy, A.3
  • 35
    • 79951609639 scopus 로고    scopus 로고
    • Insights into the metabolism and microbial biotransformation of dietary flavan-3-ols and bioactivity of their metabolites
    • Monagas, M., Urpi-Sarda, M., Sanchez-Patan, F., Llorach, R. et al., Insights into the metabolism and microbial biotransformation of dietary flavan-3-ols and bioactivity of their metabolites. Food Funct. 2010, 1, 233-253.
    • (2010) Food Funct. , vol.1 , pp. 233-253
    • Monagas, M.1    Urpi-Sarda, M.2    Sanchez-Patan, F.3    Llorach, R.4
  • 36
    • 69549091682 scopus 로고    scopus 로고
    • Metabolites are keys to understanding health effects of wine polyphenolics
    • Forester, S. C., Waterhouse, A. L., Metabolites are keys to understanding health effects of wine polyphenolics. J. Nutr. 2009, 139, 1824S-1831S.
    • (2009) J. Nutr. , vol.139
    • Forester, S.C.1    Waterhouse, A.L.2
  • 37
    • 37349007803 scopus 로고    scopus 로고
    • Anti-inflammatory activity of mangostins from Garcinia mangostana
    • Chen, L. G., Yang, L. L., Wang, C. C., Anti-inflammatory activity of mangostins from Garcinia mangostana. Food Chem. Toxicol. 2008, 46, 688-693.
    • (2008) Food Chem. Toxicol. , vol.46 , pp. 688-693
    • Chen, L.G.1    Yang, L.L.2    Wang, C.C.3
  • 38
    • 4944256956 scopus 로고    scopus 로고
    • γ-Mangostin inhibits inhibitor-κB kinase activity and decreases lipopolysaccharide-induced cyclooxygenase-2 gene expression in C6 rat glioma cells
    • Nakatani, K., Yamakuni, T., Kondo, N., Arakawa, T. et al., γ-Mangostin inhibits inhibitor-κB kinase activity and decreases lipopolysaccharide-induced cyclooxygenase-2 gene expression in C6 rat glioma cells. Mol. Pharmacol. 2004, 66, 667-674.
    • (2004) Mol. Pharmacol. , vol.66 , pp. 667-674
    • Nakatani, K.1    Yamakuni, T.2    Kondo, N.3    Arakawa, T.4


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