α- and γ-Mangostin inhibit the proliferation of colon cancer cells via β-catenin gene regulation in Wnt/cGMP signalling

Food Chemistry

Volumn 129, Issue 4, 2011, Pages 1559-1566

  Yoo, Ji Hye ^a   Kang, Kyungsu ^a   Jho, Eun Hye ^a   Chin, Young Won ^b   Kim, Jinwoong ^c   Nho, Chu Won ^a  

^a Korea Institute of Science and Technology   (South Korea)

^b Dongguk University   (South Korea)

^c Seoul National University   (South Korea)

Author keywords

Catenin; cGMP; Mangostins; PKG; Transcriptional regulation

Indexed keywords

CGMP; COLON CANCER; COLON CANCER CELLS; MANGOSTINS; PKG; PROTEIN EXPRESSIONS; TRANSCRIPTIONAL ACTIVITY; TRANSCRIPTIONAL REGULATION;

CELLS; GENES; PHOSPHORYLATION;

DISEASES;

ALPHA MANGOSTIN; BETA CATENIN; CALCIUM BINDING PROTEIN; CYCLIC GMP; CYCLIN D1; E1A ASSOCIATED P300 PROTEIN; GAMMA MANGOSTIN; GUANYLATE CYCLASE; GUANYLATE CYCLASE ACTIVATOR; LYMPHOID ENHANCER FACTOR 1; SECRETED FRIZZLED RELATED PROTEIN 2; SECRETED FRIZZLED RELATED PROTEIN 4; UNCLASSIFIED DRUG; WNT PROTEIN; XANTHONE DERIVATIVE;

ARTICLE; CANCER CELL; CANCER INHIBITION; CELL PROLIFERATION; CELL STRAIN HCT116; CELL SURVIVAL; COLON CANCER; CONTROLLED STUDY; DRUG INHIBITION; GARCINIA MANGOSTANA; HUMAN; HUMAN CELL; NONHUMAN; NUCLEOTIDE SEQUENCE; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; REAL TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; STRUCTURE ACTIVITY RELATION; TRANSCRIPTION REGULATION; WESTERN BLOTTING;

EID: 80051791437     PISSN: 03088146     EISSN: 18737072     Source Type: Journal    
DOI: 10.1016/j.foodchem.2011.06.007     Document Type: Article

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