TALENs and CRISPR/Cas9 fuel genetically engineered clinically relevant Xenopus tropicalis tumor models

Genesis

Volumn 55, Issue 1-2, 2017, Pages

  Naert, Thomas ^a   Van Nieuwenhuysen, Tom ^a   Vleminckx, Kris ^a,b  

^a GHENT UNIVERSITY   (Belgium)

^b GHENT UNIVERSITY HOSPITAL   (Belgium)

Author keywords

desmoid tumors; drug assessment; familial adenomatous polyposis; genome editing; retinoblastoma; target identification

Indexed keywords

NUCLEASE; TALEN; UNCLASSIFIED DRUG; TRANSCRIPTION ACTIVATOR LIKE EFFECTOR NUCLEASE;

CANCER CELL; CANCER RESEARCH; CRISPR CAS SYSTEM; FAMILIAL COLON POLYPOSIS; GENE; GENE EDITING; GENE INACTIVATION; GENE SILENCING; GENETIC ENGINEERING; GERMLINE MUTATION; HUMAN; MOSAICISM; NONHUMAN; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; RETINOBLASTOMA; REVERSE GENETICS; REVIEW; TUMOR MODEL; XENOPUS TROPICALIS; ANIMAL; DISEASE MODEL; GENE TARGETING; GENETICS; NEOPLASM; PATHOLOGY; XENOPUS;

ANIMALS; CRISPR-CAS SYSTEMS; DISEASE MODELS, ANIMAL; GENE TARGETING; GENETIC ENGINEERING; HUMANS; NEOPLASMS; TRANSCRIPTION ACTIVATOR-LIKE EFFECTOR NUCLEASES; XENOPUS;

EID: 85010916076     PISSN: 1526954X     EISSN: 1526968X     Source Type: Journal    
DOI: 10.1002/dvg.23005     Document Type: Review

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