Familial adenomatous polyposis at the Tel Aviv Medical Center: Demographic and clinical features

Familial Cancer

Volumn 1, Issue 2, 2001, Pages 75-82

  Rozen, Paul ^a,d   Samuel, Ziona ^a   Rabau, Micha ^b,d   Goldman, Gideon ^b,d   Shomrat, Ruth ^c   Legum, Cyril ^c,d   Orr Urtreger, Avi ^c,d  

^a Gastroenterology Department   (Israel)

^b Colorectal Surgery Unit ^*

^c TEL AVIV SOURASKY MEDICAL CENTER   (Israel)

^d TEL AVIV UNIVERSITY   (Israel)

Author keywords

Audit; Cancer; Chemoprevention; Colorectal polyps; Compliance; Desmoids; Ethnic; Familial adenomatous polyposis; Mutation; Phenotype; Prevalence

Indexed keywords

ADENOMATOUS POLYP; ARTICLE; CLINICAL FEATURE; COLORECTAL CANCER; DEMOGRAPHY; DESMOID TUMOR; ETHNIC GROUP; FAMILIAL DISEASE; GENE MUTATION; GENETIC SCREENING; HUMAN; ISRAEL; PHENOTYPE; PREVALENCE; PRIORITY JOURNAL;

ADENOMATOUS POLYPOSIS COLI; ADOLESCENT; ADULT; AGED; CHILD; COLORECTAL NEOPLASMS; ETHNIC GROUPS; FEMALE; GENETIC SCREENING; HUMANS; INCIDENCE; ISRAEL; JEWS; MALE; MIDDLE AGED; PATIENT COMPLIANCE; PEDIGREE; PHENOTYPE;

EID: 0035774098     PISSN: 13899600     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1013888226756     Document Type: Article

References (24)

1. Menko FH. Genetics of Colorectal Cancer for Clinical Practice. Dordrecht, The Netherlands: Kluwer, 1993: 83-99.
2. King JE, Dozois RR, Lindor NM, Ahlquist DA. Care of patients and their families with familial adenomatous polyposis. Mayo Clin Proc 2000; 75: 57-68.
3. Galle TS, Juel K, Bulow S. Causes of death in familial adenomatous polyposis. Scand J Gastroenterol 1999; 34; 808-12.
4. Steinbach G, Lynch PM, Phillips RKS et al. The effect of celecoxib, a cyclooxygenase-2 inhibitor, in familial adenomatous polyposis. N Eng J Med 2000; 342: 1946-52.
5. Anthony T, Rodriguez-Bigas MA, Weber TK, Petrelli NJ. Desmoid tumors. J Am Coll Surg 1996; 182: 369-77.
6. Debinski HS, Spigelman AD, Hatfield A et al. Upper intestinal surveillance in familial adenomatous polyposis. Eur J Cancer 1995; 31: 1149-53.
7. Zwick A, Munir M, Ryan CK et al. Gastric adenocarcinoma and dysplasia in fundic gland polyps of a patient with attenuated adenomatous polyposis coli. Gastroenterology 1997; 113: 659-63.
8. Bertoni G, Sassatelli R, Nigrisoli E et al. Dysplastic changes in gastric fundic gland polyps of patients with familial adenomatous polyposis. Ital J Gastroenterol Hepatol 1999; 31: 192-97.
9. Bertoni G, Sassatelli R, Nigrisoli E et al. First observation of microadenomas in the ileal mucosa of patients with familial adenomatous polyposis and colectomies. Gastroenterology 1995; 109: 374-80.
10. Parc YR, Olschwang S, Desaint B et al. Familial adenomatous polyposis: Prevalence of adenomas in the ileal pouch after restorative proctocolectomy. Ann Surg 2001; 233: 360-4.
11. Gilson TP, Sollenberger LL. Adenocarcinoma of an ileostomy in a patient with familial adenomatous polyposis. Report of a case. Dis Colon Rectum 1992; 35: 261-5.
12. Nugent KP, Phillips RKS. Rectal cancer risk in older patients with familial adenomatous polyposis and an ileorectal anastomosis: A cause for concern. Br J Surg 1992; 79: 1204-6.
13. Phillips RKS, Spigelman AD. Can we safely delay or avoid prophylactic colectomy in familial adenomatous polyposis?. Br J Surg 1996; 83: 769-70.
14. Ponz de Leon M, Benatti P, Percesepe A et al. Clinical features and genotype-phenotype correlations in 41 Italian families with adenomatosis coli. Ital J Gastroenterol Hepatol 1999; 31: 850-60.
15. Nagase H, Miyoshi Y, Horii A et al. Correlation between the location of germ-line mutations in the APC gene and the number of colorectal polyps in familial adenomatous polyposis patients. Cancer Res 1992; 52: 4055-7.
16. Wu JS, Paul P, McGannon EA, Church JM. APC genotype, polyp number and surgical options in familial adenomatous polyposis. Ann Surg 1998; 227: 57-62.
17. Bulow C, Vassen H, Jarvinen A et al. Ileorectal anastomosis is appropriate for a subgroup of patients with familial adenomatous polyposis. Gastroenterology 2000; 119: 1454-60.
18. 1309 mutation: A possible explanation for genotype-phenotype correlations in familial adenomatous polyposis. Cancer Res 1999; 59: 1857-60.
19. Rozen P, Samuel Z, Shomrat R, Legum C. Notable intrafamilial phenotypic variablility in a kindred with familial adenomatous polyposis and an APC mutation in exon 9. Gut 1999; 45: 829-33.
20. Houlston R, Crabtree M, Phillips R, Tomlinson I. Explaining differences in the severity of familial adenomatous polyposis and the search for modifier genes. (Editorial) Gut 2001; 48: 1-5.
21. Björk J, Akerbrant L, Iselius L et al. Epidemiology of familial adenomatous polyposis in Sweden: Changes over time and differences in phenotype between males and females. Scand J Gastroenterol 1999; 34: 1230-5.
22. Laken SJ, Papadopoulos N, Petersen GM et al. Analysis of masked mutations in familial adenomatous polyposis. Proc Natl Acad Sci 1999; 96: 2322-6.
23. Friedl W, Caspari R, Sengteller M et al. Can APC mutation analysis contribute to therapeutic decisions in familial adenomatous polyposis? Experience from 680 FAP families. Gut 2001; 48: 515-21.
24. Arvanitis JL, Jagelman DG, Fazio VW et al. Mortality in patients with familial adenomatous polyposis. Dis Colon Rectum 1990; 33: 639-42.