CRISPR/Cas9: An inexpensive, efficient loss of function tool to screen human disease genes in Xenopus

Developmental Biology

Volumn 408, Issue 2, 2015, Pages 196-204

  Bhattacharya, Dipankan ^a   Marfo, Chris A ^a   Li, Davis ^a   Lane, Maura ^a   Khokha, Mustafa K ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Beta catenin; Cas9 protein; Ccdc40; CRISPR; Dnah9; Foxj1; Fragment analysis; Morpholino; Pax8; Tyrosinase; Xenopus tropicalis

Indexed keywords

CASPASE 9; CRISPR ASSOCIATED PROTEIN; MESSENGER RNA; TRANSCRIPTION FACTOR PAX8;

ANIMAL CELL; ARTICLE; CCDC40 GENE; CELL DENSITY; CILIARY DYSKINESIA; CONGENITAL MALFORMATION; CONTROLLED STUDY; DNAH9 GENE; EMBRYO; EPIDERMIS CELL; FOXJ1 GENE; GALNT11 GENE; GENE DELETION; GENE FUNCTION; GENE LOCUS; HETEROTAXY SYNDROME; NONHUMAN; PHENOTYPE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN FOLDING; PROTEIN FUNCTION; PROTEIN MODIFICATION; XENOPUS TROPICALIS; ANIMAL; BIOLOGICAL MODEL; CONGENITAL HEART MALFORMATION; CRISPR CAS SYSTEM; DISEASES; EMBRYO DEVELOPMENT; EMBRYOLOGY; GENE SILENCING; GENETIC SCREENING; GENETICS; HUMAN; PROCEDURES; RNA EDITING; XENOPUS;

ANIMALS; CRISPR-CAS SYSTEMS; DISEASE; EMBRYONIC DEVELOPMENT; GENE KNOCKDOWN TECHNIQUES; GENETIC TESTING; HEART DEFECTS, CONGENITAL; HUMANS; MODELS, GENETIC; RNA EDITING; XENOPUS;

EID: 84955414846     PISSN: 00121606     EISSN: 1095564X     Source Type: Journal    
DOI: 10.1016/j.ydbio.2015.11.003     Document Type: Article

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