-
1
-
-
84979523619
-
Targeted mutagenesis using CRISPR/Cas system in medaka
-
Ansai, S. & Kinoshita, M. (2014) Targeted mutagenesis using CRISPR/Cas system in medaka. Biol. Open 3, 362–371.
-
(2014)
Biol. Open
, vol.3
, pp. 362-371
-
-
Ansai, S.1
Kinoshita, M.2
-
2
-
-
84903516238
-
Microhomology-based choice of Cas9 nuclease target sites
-
Bae, S., Kweon, J., Kim, H.S. & Kim, J.-S. (2014a) Microhomology-based choice of Cas9 nuclease target sites. Nat. Methods 11, 705–706.
-
(2014)
Nat. Methods
, vol.11
, pp. 705-706
-
-
Bae, S.1
Kweon, J.2
Kim, H.S.3
Kim, J.-S.4
-
3
-
-
84896308706
-
Cas-OFFinder: a fast and versatile algorithm that searches for potential off-target sites of Cas9 RNA-guided endonucleases
-
Bae, S., Park, J. & Kim, J.S. (2014b) Cas-OFFinder: a fast and versatile algorithm that searches for potential off-target sites of Cas9 RNA-guided endonucleases. Bioinformatics 30, 1473–1475.
-
(2014)
Bioinformatics
, vol.30
, pp. 1473-1475
-
-
Bae, S.1
Park, J.2
Kim, J.S.3
-
4
-
-
84924287971
-
A high-throughput screening strategy for detecting CRISPR-Cas9 induced mutations using next-generation sequencing
-
Bell, C.C., Magor, G.W., Gillinder, K.R. & Perkins, A.C. (2014) A high-throughput screening strategy for detecting CRISPR-Cas9 induced mutations using next-generation sequencing. BMC Genomics 15, 1002.
-
(2014)
BMC Genomics
, vol.15
, pp. 1002
-
-
Bell, C.C.1
Magor, G.W.2
Gillinder, K.R.3
Perkins, A.C.4
-
5
-
-
84955414846
-
CRISPR/Cas9: An inexpensive, efficient loss of function tool to screen human disease genes in Xenopus
-
Bhattacharya, D., Marfo, C.A., Li, D., Lane, M. & Khokha, M.K. (2015) CRISPR/Cas9: An inexpensive, efficient loss of function tool to screen human disease genes in Xenopus. Dev. Biol. 408, 196–204.
-
(2015)
Dev. Biol.
, vol.408
, pp. 196-204
-
-
Bhattacharya, D.1
Marfo, C.A.2
Li, D.3
Lane, M.4
Khokha, M.K.5
-
6
-
-
84890805562
-
Biallelic genome modification in F-0 Xenopus tropicalis embryos using the CRISPR/Cas system
-
Blitz, I.L., Biesinger, J., Xie, X.H. & Cho, K.W.Y. (2013) Biallelic genome modification in F-0 Xenopus tropicalis embryos using the CRISPR/Cas system. Genesis 51, 827–834.
-
(2013)
Genesis
, vol.51
, pp. 827-834
-
-
Blitz, I.L.1
Biesinger, J.2
Xie, X.H.3
Cho, K.W.Y.4
-
7
-
-
84873729095
-
Multiplex genome engineering using CRISPR/Cas systems
-
Cong, L., Ran, F.A., Cox, D., Lin, S.L., Barretto, R., Habib, N., Hsu, P.D., Wu, X.B., Jiang, W.Y., Marraffini, L.A. & Zhang, F. (2013) Multiplex genome engineering using CRISPR/Cas systems. Science 339, 819–823.
-
(2013)
Science
, vol.339
, pp. 819-823
-
-
Cong, L.1
Ran, F.A.2
Cox, D.3
Lin, S.L.4
Barretto, R.5
Habib, N.6
Hsu, P.D.7
Wu, X.B.8
Jiang, W.Y.9
Marraffini, L.A.10
Zhang, F.11
-
8
-
-
84875754465
-
Nucleotide-resolution DNA double-strand break mapping by next-generation sequencing
-
Crosetto, N., Mitra, A., Silva, M.J., Bienko, M., Dojer, N., Wang, Q., Karaca, E., Chiarle, R., Skrzypczak, M., Ginalski, K., Pasero, P., Rowicka, M. & Dikic, I. (2013) Nucleotide-resolution DNA double-strand break mapping by next-generation sequencing. Nat. Methods 10, 361–365.
-
(2013)
Nat. Methods
, vol.10
, pp. 361-365
-
-
Crosetto, N.1
Mitra, A.2
Silva, M.J.3
Bienko, M.4
Dojer, N.5
Wang, Q.6
Karaca, E.7
Chiarle, R.8
Skrzypczak, M.9
Ginalski, K.10
Pasero, P.11
Rowicka, M.12
Dikic, I.13
-
9
-
-
84874382632
-
Slc45a2 and V-ATPase are regulators of melanosomal pH homeostasis in zebrafish, providing a mechanism for human pigment evolution and disease
-
Dooley, C.M., Schwarz, H., Mueller, K.P., Mongera, A., Konantz, M., Neuhauss, S.C.F., Nusslein-Volhard, C. & Geisler, R. (2013) Slc45a2 and V-ATPase are regulators of melanosomal pH homeostasis in zebrafish, providing a mechanism for human pigment evolution and disease. Pigment Cell Melanoma Res. 26, 205–217.
-
(2013)
Pigment Cell Melanoma Res.
, vol.26
, pp. 205-217
-
-
Dooley, C.M.1
Schwarz, H.2
Mueller, K.P.3
Mongera, A.4
Konantz, M.5
Neuhauss, S.C.F.6
Nusslein-Volhard, C.7
Geisler, R.8
-
10
-
-
84913594397
-
The new frontier of genome engineering with CRISPR-Cas9
-
Doudna, J.A. & Charpentier, E. (2014) The new frontier of genome engineering with CRISPR-Cas9. Science 346, 1258096.
-
(2014)
Science
, vol.346
, pp. 1258096
-
-
Doudna, J.A.1
Charpentier, E.2
-
11
-
-
84880570576
-
High-frequency off-target mutagenesis induced by CRISPR-Cas nucleases in human cells
-
Fu, Y.F., Foden, J.A., Khayter, C., Maeder, M.L., Reyon, D., Joung, J.K. & Sander, J.D. (2013) High-frequency off-target mutagenesis induced by CRISPR-Cas nucleases in human cells. Nat. Biotechnol. 31, 822–826.
-
(2013)
Nat. Biotechnol.
, vol.31
, pp. 822-826
-
-
Fu, Y.F.1
Foden, J.A.2
Khayter, C.3
Maeder, M.L.4
Reyon, D.5
Joung, J.K.6
Sander, J.D.7
-
12
-
-
84892771868
-
Efficient RNA/Cas9-mediated genome editing in Xenopus tropicalis
-
Guo, X.G., Zhang, T.J., Hu, Z., Zhang, Y.Q., Shi, Z.Y., Wang, Q.H., Cui, Y., Wang, F.Q., Zhao, H. & Chen, Y.L. (2014) Efficient RNA/Cas9-mediated genome editing in Xenopus tropicalis. Development 141, 707–714.
-
(2014)
Development
, vol.141
, pp. 707-714
-
-
Guo, X.G.1
Zhang, T.J.2
Hu, Z.3
Zhang, Y.Q.4
Shi, Z.Y.5
Wang, Q.H.6
Cui, Y.7
Wang, F.Q.8
Zhao, H.9
Chen, Y.L.10
-
13
-
-
81055157765
-
Xenopus research: metamorphosed by genetics and genomics
-
Harland, R.M. & Grainger, R.M. (2011) Xenopus research: metamorphosed by genetics and genomics. Trends Genet. 27, 507–515.
-
(2011)
Trends Genet.
, vol.27
, pp. 507-515
-
-
Harland, R.M.1
Grainger, R.M.2
-
14
-
-
77951823093
-
The genome of the Western Clawed Frog Xenopus tropicalis
-
Hellsten, U., Harland, R.M., Gilchrist, M.J. et al. (2010) The genome of the Western Clawed Frog Xenopus tropicalis. Science 328, 633–636.
-
(2010)
Science
, vol.328
, pp. 633-636
-
-
Hellsten, U.1
Harland, R.M.2
Gilchrist, M.J.3
-
15
-
-
84874617789
-
Efficient genome editing in zebrafish using a CRISPR-Cas system
-
Hwang, W.Y., Fu, Y.F., Reyon, D., Maeder, M.L., Tsai, S.Q., Sander, J.D., Peterson, R.T., Yeh, J.R.J. & Joung, J.K. (2013) Efficient genome editing in zebrafish using a CRISPR-Cas system. Nat. Biotechnol. 31, 227–229.
-
(2013)
Nat. Biotechnol.
, vol.31
, pp. 227-229
-
-
Hwang, W.Y.1
Fu, Y.F.2
Reyon, D.3
Maeder, M.L.4
Tsai, S.Q.5
Sander, J.D.6
Peterson, R.T.7
Yeh, J.R.J.8
Joung, J.K.9
-
16
-
-
84964990221
-
Highly efficient bi-allelic mutation rates using TALENs in Xenopus tropicalis
-
Ishibashi, S., Cliffe, R. & Amaya, E. (2012) Highly efficient bi-allelic mutation rates using TALENs in Xenopus tropicalis. Biol. Open 1, 1273–1276.
-
(2012)
Biol. Open
, vol.1
, pp. 1273-1276
-
-
Ishibashi, S.1
Cliffe, R.2
Amaya, E.3
-
17
-
-
84939472973
-
Xenbase: core features, data acquisition, and data processing
-
James-Zorn, C., Ponferrada, V.G., Burns, K.A., Fortriede, J.D., Lotay, V.S., Liu, Y., Karpinka, J.B., Karimi, K., Zorn, A.M. & Vize, P.D. (2015) Xenbase: core features, data acquisition, and data processing. Genesis 53, 486–497.
-
(2015)
Genesis
, vol.53
, pp. 486-497
-
-
James-Zorn, C.1
Ponferrada, V.G.2
Burns, K.A.3
Fortriede, J.D.4
Lotay, V.S.5
Liu, Y.6
Karpinka, J.B.7
Karimi, K.8
Zorn, A.M.9
Vize, P.D.10
-
18
-
-
84865070369
-
A programmable dual-RNA-guided DNA endonuclease in adaptive bacterial immunity
-
Jinek, M., Chylinski, K., Fonfara, I., Hauer, M., Doudna, J.A. & Charpentier, E. (2012) A programmable dual-RNA-guided DNA endonuclease in adaptive bacterial immunity. Science 337, 816–821.
-
(2012)
Science
, vol.337
, pp. 816-821
-
-
Jinek, M.1
Chylinski, K.2
Fonfara, I.3
Hauer, M.4
Doudna, J.A.5
Charpentier, E.6
-
19
-
-
84858000785
-
Xenopus white papers and resources: folding functional genomics and genetics into the frog
-
Khokha, M.K. (2012) Xenopus white papers and resources: folding functional genomics and genetics into the frog. Genesis 50, 133–142.
-
(2012)
Genesis
, vol.50
, pp. 133-142
-
-
Khokha, M.K.1
-
20
-
-
84923846574
-
Digenome-seq: genome-wide profiling of CRISPR-Cas9 off-target effects in human cells
-
Kim, D., Bae, S., Park, J., Kim, E., Kim, S., Yu, H.R., Hwang, J., Kim, J.I. & Kim, J.S. (2015) Digenome-seq: genome-wide profiling of CRISPR-Cas9 off-target effects in human cells. Nat. Methods 12, 237–243.
-
(2015)
Nat. Methods
, vol.12
, pp. 237-243
-
-
Kim, D.1
Bae, S.2
Park, J.3
Kim, E.4
Kim, S.5
Yu, H.R.6
Hwang, J.7
Kim, J.I.8
Kim, J.S.9
-
21
-
-
67650045497
-
Targeted genome editing in human cells with zinc finger nucleases constructed via modular assembly
-
Kim, H.J., Lee, H.J., Kim, H., Cho, S.W. & Kim, J.-S. (2009) Targeted genome editing in human cells with zinc finger nucleases constructed via modular assembly. Genome Res. 19, 1279–1288.
-
(2009)
Genome Res.
, vol.19
, pp. 1279-1288
-
-
Kim, H.J.1
Lee, H.J.2
Kim, H.3
Cho, S.W.4
Kim, J.-S.5
-
22
-
-
84892897176
-
Genotyping with CRISPR-Cas-derived RNA-guided endonucleases
-
Kim, J.M., Kim, D., Kim, S. & Kim, J.S. (2014a) Genotyping with CRISPR-Cas-derived RNA-guided endonucleases. Nat. Commun. 5, 3157.
-
(2014)
Nat. Commun.
, vol.5
, pp. 3157
-
-
Kim, J.M.1
Kim, D.2
Kim, S.3
Kim, J.S.4
-
23
-
-
84901834420
-
Highly efficient RNA-guided genome editing in human cells via delivery of purified Cas9 ribonucleoproteins
-
Kim, S., Kim, D., Cho, S.W., Kim, J. & Kim, J.S. (2014b) Highly efficient RNA-guided genome editing in human cells via delivery of purified Cas9 ribonucleoproteins. Genome Res. 24, 1012–1019.
-
(2014)
Genome Res.
, vol.24
, pp. 1012-1019
-
-
Kim, S.1
Kim, D.2
Cho, S.W.3
Kim, J.4
Kim, J.S.5
-
24
-
-
84927695100
-
Genome engineering with CRISPR-Cas9 in the mosquito Aedes aegypti
-
Kistler, K.E., Vosshall, L.B. & Matthews, B.J. (2015) Genome engineering with CRISPR-Cas9 in the mosquito Aedes aegypti. Cell Rep. 11, 51–60.
-
(2015)
Cell Rep.
, vol.11
, pp. 51-60
-
-
Kistler, K.E.1
Vosshall, L.B.2
Matthews, B.J.3
-
25
-
-
84930216507
-
Efficient multiple genome modifications induced by the crRNAs, tracrRNA and Cas9 protein complex in zebrafish
-
Kotani, H., Taimatsu, K., Ohga, R., Ota, S. & Kawahara, A. (2015) Efficient multiple genome modifications induced by the crRNAs, tracrRNA and Cas9 protein complex in zebrafish. PLoS One 10, e0128319.
-
(2015)
PLoS One
, vol.10
-
-
Kotani, H.1
Taimatsu, K.2
Ohga, R.3
Ota, S.4
Kawahara, A.5
-
26
-
-
0029806183
-
Transgenic Xenopus embryos from sperm nuclear transplantations reveal FGF signaling requirements during gastrulation
-
Kroll, K.L. & Amaya, E. (1996) Transgenic Xenopus embryos from sperm nuclear transplantations reveal FGF signaling requirements during gastrulation. Development 122, 3173–3183.
-
(1996)
Development
, vol.122
, pp. 3173-3183
-
-
Kroll, K.L.1
Amaya, E.2
-
27
-
-
84903545084
-
Genome-wide analysis reveals characteristics of off-target sites bound by the Cas9 endonuclease
-
Kuscu, C., Arslan, S., Singh, R., Thorpe, J. & Adli, M. (2014) Genome-wide analysis reveals characteristics of off-target sites bound by the Cas9 endonuclease. Nat. Biotechnol. 32, 677–683.
-
(2014)
Nat. Biotechnol.
, vol.32
, pp. 677-683
-
-
Kuscu, C.1
Arslan, S.2
Singh, R.3
Thorpe, J.4
Adli, M.5
-
28
-
-
84904572233
-
RNA-guided genome editing in Drosophila with the purified Cas9 protein
-
Lee, J.-S., Kwak, S.-J., Kim, J., Kim, A.-K., Noh, H.M., Kim, J.-S. & Yu, K. (2014) RNA-guided genome editing in Drosophila with the purified Cas9 protein. G3 4, 1291–1295.
-
(2014)
G3
, vol.4
, pp. 1291-1295
-
-
Lee, J.-S.1
Kwak, S.-J.2
Kim, J.3
Kim, A.-K.4
Noh, H.M.5
Kim, J.-S.6
Yu, K.7
-
29
-
-
68549104404
-
The sequence alignment/map format and SAMtools
-
Li, H., Handsaker, B., Wysoker, A., Fennell, T., Ruan, J., Homer, N., Marth, G., Abecasis, G., Durbin, R. & Genome Project Data, P. (2009) The sequence alignment/map format and SAMtools. Bioinformatics 25, 2078–2079.
-
(2009)
Bioinformatics
, vol.25
, pp. 2078-2079
-
-
Li, H.1
Handsaker, B.2
Wysoker, A.3
Fennell, T.4
Ruan, J.5
Homer, N.6
Marth, G.7
Abecasis, G.8
Durbin, R.9
-
30
-
-
41949111544
-
Leukocyte tyrosine kinase functions in pigment cell development
-
Lopes, S.S., Yang, X., Mueller, J., Carney, T.J., McAdow, A.R., Rauch, G.-J., Jacoby, A.S., Hurst, L.D., Delfino-Machin, M., Haffter, P., Geisler, R., Johnson, S.L., Ward, A. & Kelsh, R.N. (2008) Leukocyte tyrosine kinase functions in pigment cell development. PLoS Genet. 4, e1000026.
-
(2008)
PLoS Genet.
, vol.4
-
-
Lopes, S.S.1
Yang, X.2
Mueller, J.3
Carney, T.J.4
McAdow, A.R.5
Rauch, G.-J.6
Jacoby, A.S.7
Hurst, L.D.8
Delfino-Machin, M.9
Haffter, P.10
Geisler, R.11
Johnson, S.L.12
Ward, A.13
Kelsh, R.N.14
-
31
-
-
84873734105
-
RNA-guided human genome engineering via Cas9
-
Mali, P., Yang, L.H., Esvelt, K.M., Aach, J., Guell, M., DiCarlo, J.E., Norville, J.E. & Church, G.M. (2013) RNA-guided human genome engineering via Cas9. Science 339, 823–826.
-
(2013)
Science
, vol.339
, pp. 823-826
-
-
Mali, P.1
Yang, L.H.2
Esvelt, K.M.3
Aach, J.4
Guell, M.5
DiCarlo, J.E.6
Norville, J.E.7
Church, G.M.8
-
32
-
-
54849404458
-
MMEJ repair of double-strand breaks (director's cut): deleted sequences and alternative endings
-
McVey, M. & Lee, S.E. (2008) MMEJ repair of double-strand breaks (director's cut): deleted sequences and alternative endings. Trends Genet. 24, 529–538.
-
(2008)
Trends Genet.
, vol.24
, pp. 529-538
-
-
McVey, M.1
Lee, S.E.2
-
33
-
-
84957922305
-
The expression of TALEN before fertilization provides a rapid knock-out phenotype in Xenopus laevis founder embryos
-
Miyamoto, K., Suzuki, K.T., Suzuki, M., Sakane, Y., Sakuma, T., Herberg, S., Simeone, A., Simpson, D., Jullien, J., Yamamoto, T. & Gurdon, J.B. (2015) The expression of TALEN before fertilization provides a rapid knock-out phenotype in Xenopus laevis founder embryos. PLoS One 10, e0142946.
-
(2015)
PLoS One
, vol.10
-
-
Miyamoto, K.1
Suzuki, K.T.2
Suzuki, M.3
Sakane, Y.4
Sakuma, T.5
Herberg, S.6
Simeone, A.7
Simpson, D.8
Jullien, J.9
Yamamoto, T.10
Gurdon, J.B.11
-
34
-
-
84959123021
-
CRISPRscan: designing highly efficient sgRNAs for CRISPR-Cas9 targeting in vivo
-
Moreno-Mateos, M.A., Vejnar, C.E., Beaudoin, J.D., Fernandez, J.P., Mis, E.K., Khokha, M.K. & Giraldez, A.J. (2015) CRISPRscan: designing highly efficient sgRNAs for CRISPR-Cas9 targeting in vivo. Nat. Methods 12, 982–988.
-
(2015)
Nat. Methods
, vol.12
, pp. 982-988
-
-
Moreno-Mateos, M.A.1
Vejnar, C.E.2
Beaudoin, J.D.3
Fernandez, J.P.4
Mis, E.K.5
Khokha, M.K.6
Giraldez, A.J.7
-
35
-
-
84929142256
-
CRISPRdirect: software for designing CRISPR/Cas guide RNA with reduced off-target sites
-
Naito, Y., Hino, K., Bono, H. & Ui-Tei, K. (2015) CRISPRdirect: software for designing CRISPR/Cas guide RNA with reduced off-target sites. Bioinformatics 31, 1120–1123.
-
(2015)
Bioinformatics
, vol.31
, pp. 1120-1123
-
-
Naito, Y.1
Hino, K.2
Bono, H.3
Ui-Tei, K.4
-
36
-
-
84925457676
-
Cas9-based genome editing in Xenopus tropicalis
-
Nakayama, T., Blitz, I.L., Fish, M.B., Odeleye, A.O., Manohar, S., Cho, K.W. & Grainger, R.M. (2014) Cas9-based genome editing in Xenopus tropicalis. Methods Enzymol. 546, 355–375.
-
(2014)
Methods Enzymol.
, vol.546
, pp. 355-375
-
-
Nakayama, T.1
Blitz, I.L.2
Fish, M.B.3
Odeleye, A.O.4
Manohar, S.5
Cho, K.W.6
Grainger, R.M.7
-
37
-
-
84890787845
-
Simple and efficient CRISPR/Cas9-mediated targeted mutagenesis in Xenopus tropicalis
-
Nakayama, T., Fish, M.B., Fisher, M., Oomen-Hajagos, J., Thomsen, G.H. & Grainger, R.M. (2013) Simple and efficient CRISPR/Cas9-mediated targeted mutagenesis in Xenopus tropicalis. Genesis 51, 835–843.
-
(2013)
Genesis
, vol.51
, pp. 835-843
-
-
Nakayama, T.1
Fish, M.B.2
Fisher, M.3
Oomen-Hajagos, J.4
Thomsen, G.H.5
Grainger, R.M.6
-
39
-
-
84903191807
-
Multiple genome modifications by the CRISPR/Cas9 system in zebrafish
-
Ota, S., Hisano, Y., Ikawa, Y. & Kawahara, A. (2014) Multiple genome modifications by the CRISPR/Cas9 system in zebrafish. Genes Cells 19, 555–564.
-
(2014)
Genes Cells
, vol.19
, pp. 555-564
-
-
Ota, S.1
Hisano, Y.2
Ikawa, Y.3
Kawahara, A.4
-
40
-
-
84878349760
-
Efficient identification of TALEN-mediated genome modifications using heteroduplex mobility assays
-
Ota, S., Hisano, Y., Muraki, M., Hoshijima, K., Dahlem, T.J., Grunwald, D.J., Okada, Y. & Kawahara, A. (2013) Efficient identification of TALEN-mediated genome modifications using heteroduplex mobility assays. Genes Cells 18, 450–458.
-
(2013)
Genes Cells
, vol.18
, pp. 450-458
-
-
Ota, S.1
Hisano, Y.2
Muraki, M.3
Hoshijima, K.4
Dahlem, T.J.5
Grunwald, D.J.6
Okada, Y.7
Kawahara, A.8
-
41
-
-
84941248689
-
High efficiency, homology-directed genome editing in Caenorhabditis elegans using CRISPR-Cas9 ribonucleoprotein complexes
-
Paix, A., Folkmann, A., Rasoloson, D. & Seydoux, G. (2015) High efficiency, homology-directed genome editing in Caenorhabditis elegans using CRISPR-Cas9 ribonucleoprotein complexes. Genetics 201, 47–54.
-
(2015)
Genetics
, vol.201
, pp. 47-54
-
-
Paix, A.1
Folkmann, A.2
Rasoloson, D.3
Seydoux, G.4
-
42
-
-
84908031939
-
Making designer mutants in model organisms
-
Peng, Y., Clark, K.J., Campbell, J.M., Panetta, M.R., Guo, Y. & Ekker, S.C. (2014) Making designer mutants in model organisms. Development 141, 4042–4054.
-
(2014)
Development
, vol.141
, pp. 4042-4054
-
-
Peng, Y.1
Clark, K.J.2
Campbell, J.M.3
Panetta, M.R.4
Guo, Y.5
Ekker, S.C.6
-
43
-
-
84887010498
-
Genome engineering using the CRISPR-Cas9 system
-
Ran, F.A., Hsu, P.D., Wright, J., Agarwala, V., Scott, D.A. & Zhang, F. (2013) Genome engineering using the CRISPR-Cas9 system. Nat. Protoc. 8, 2281–2308.
-
(2013)
Nat. Protoc.
, vol.8
, pp. 2281-2308
-
-
Ran, F.A.1
Hsu, P.D.2
Wright, J.3
Agarwala, V.4
Scott, D.A.5
Zhang, F.6
-
44
-
-
24344442989
-
Depletion of Bmp2, Bmp4, Bmp7 and Spemann organizer signals induces massive brain formation in Xenopus embryos
-
Reversade, B., Kuroda, H., Lee, H., Mays, A. & De Robertis, E.M. (2005) Depletion of Bmp2, Bmp4, Bmp7 and Spemann organizer signals induces massive brain formation in Xenopus embryos. Development 132, 3381–3392.
-
(2005)
Development
, vol.132
, pp. 3381-3392
-
-
Reversade, B.1
Kuroda, H.2
Lee, H.3
Mays, A.4
De Robertis, E.M.5
-
45
-
-
84899942955
-
Engineering Xenopus embryos for phenotypic drug discovery screening
-
Schmitt, S.M., Gull, M. & Brandli, A.W. (2014) Engineering Xenopus embryos for phenotypic drug discovery screening. Adv. Drug Deliv. Rev. 69, 225–246.
-
(2014)
Adv. Drug Deliv. Rev.
, vol.69
, pp. 225-246
-
-
Schmitt, S.M.1
Gull, M.2
Brandli, A.W.3
-
46
-
-
84957595555
-
Digital detection of endonuclease mediated gene disruption in the HIV provirus
-
Sedlak, R.H., Liang, S., Niyonzima, N., Feelixge, H.S.D., Roychoudhury, P., Greninger, A.L., Weber, N.D., Boissel, S., Scharenberg, A.M., Cheng, A., Magaret, A., Bumgarner, R., Stone, D. & Jerome, K.R. (2016) Digital detection of endonuclease mediated gene disruption in the HIV provirus. Sci. Rep. 6, 20064.
-
(2016)
Sci. Rep.
, vol.6
, pp. 20064
-
-
Sedlak, R.H.1
Liang, S.2
Niyonzima, N.3
Feelixge, H.S.D.4
Roychoudhury, P.5
Greninger, A.L.6
Weber, N.D.7
Boissel, S.8
Scharenberg, A.M.9
Cheng, A.10
Magaret, A.11
Bumgarner, R.12
Stone, D.13
Jerome, K.R.14
-
47
-
-
84891704542
-
Highly efficient gene knockout in mice and zebrafish with RNA-guided endonucleases
-
Sung, Y.H., Kim, J.M., Kim, H.T., Lee, J., Jeon, J., Jin, Y., Choi, J.H., Ban, Y.H., Ha, S.J., Kim, C.H., Lee, H.W. & Kim, J.S. (2014) Highly efficient gene knockout in mice and zebrafish with RNA-guided endonucleases. Genome Res. 24, 125–131.
-
(2014)
Genome Res.
, vol.24
, pp. 125-131
-
-
Sung, Y.H.1
Kim, J.M.2
Kim, H.T.3
Lee, J.4
Jeon, J.5
Jin, Y.6
Choi, J.H.7
Ban, Y.H.8
Ha, S.J.9
Kim, C.H.10
Lee, H.W.11
Kim, J.S.12
-
48
-
-
84943371851
-
Genome editing using site-specific nucleases in Amphibians
-
In, (ed., T. Yamamoto, Tokyo, Springer Japan Press
-
Suzuki, K.T. & Hayashi, T. (2015) Genome editing using site-specific nucleases in Amphibians. In: Targeted Genome Editing Using Site-Specific Nucleases ZFNs, TALENs, and the CRISPR/Cas9 System (ed. T. Yamamoto), pp. 133–149. Tokyo: Springer Japan Press.
-
(2015)
Targeted Genome Editing Using Site-Specific Nucleases ZFNs, TALENs, and the CRISPR/Cas9 System
, pp. 133-149
-
-
Suzuki, K.T.1
Hayashi, T.2
-
49
-
-
84974633017
-
High efficiency TALENs enable F0 functional analysis by targeted gene disruption in Xenopus laevis embryos
-
Suzuki, K.T., Isoyama, Y., Kashiwagi, K., Sakuma, T., Ochiai, H., Sakamoto, N., Furuno, N., Kashiwagi, A. & Yamamoto, T. (2013) High efficiency TALENs enable F0 functional analysis by targeted gene disruption in Xenopus laevis embryos. Biol. Open 2, 448–452.
-
(2013)
Biol. Open
, vol.2
, pp. 448-452
-
-
Suzuki, K.T.1
Isoyama, Y.2
Kashiwagi, K.3
Sakuma, T.4
Ochiai, H.5
Sakamoto, N.6
Furuno, N.7
Kashiwagi, A.8
Yamamoto, T.9
-
50
-
-
84923266604
-
GUIDE-seq enables genome-wide profiling of off-target cleavage by CRISPR-Cas nucleases
-
Tsai, S.Q., Zheng, Z., Nguyen, N.T., Liebers, M., Topkar, V.V., Thapar, V., Wyvekens, N., Khayter, C., Iafrate, A.J., Le, L.P., Aryee, M.J. & Joung, J.K. (2015) GUIDE-seq enables genome-wide profiling of off-target cleavage by CRISPR-Cas nucleases. Nat. Biotechnol. 33, 187–197.
-
(2015)
Nat. Biotechnol.
, vol.33
, pp. 187-197
-
-
Tsai, S.Q.1
Zheng, Z.2
Nguyen, N.T.3
Liebers, M.4
Topkar, V.V.5
Thapar, V.6
Wyvekens, N.7
Khayter, C.8
Iafrate, A.J.9
Le, L.P.10
Aryee, M.J.11
Joung, J.K.12
-
51
-
-
18944373328
-
Highly efficient endogenous human gene correction using designed zinc-finger nucleases
-
Urnov, F.D., Miller, J.C., Lee, Y.L., Beausejour, C.M., Rock, J.M., Augustus, S., Jamieson, A.C., Porteus, M.H., Gregory, P.D. & Holmes, M.C. (2005) Highly efficient endogenous human gene correction using designed zinc-finger nucleases. Nature 435, 646–651.
-
(2005)
Nature
, vol.435
, pp. 646-651
-
-
Urnov, F.D.1
Miller, J.C.2
Lee, Y.L.3
Beausejour, C.M.4
Rock, J.M.5
Augustus, S.6
Jamieson, A.C.7
Porteus, M.H.8
Gregory, P.D.9
Holmes, M.C.10
-
52
-
-
84930611267
-
High-throughput gene targeting and phenotyping in zebrafish using CRISPR/Cas9
-
Varshney, G.K., Pei, W.H., LaFave, M.C. et al. (2015) High-throughput gene targeting and phenotyping in zebrafish using CRISPR/Cas9. Genome Res. 25, 1030–1042.
-
(2015)
Genome Res.
, vol.25
, pp. 1030-1042
-
-
Varshney, G.K.1
Pei, W.H.2
LaFave, M.C.3
-
53
-
-
84924666891
-
Comparison of T7E1 and surveyor mismatch cleavage assays to detect mutations triggered by engineered nucleases
-
Vouillot, L., Thelie, A. & Pollet, N. (2015) Comparison of T7E1 and surveyor mismatch cleavage assays to detect mutations triggered by engineered nucleases. G3 (Bethesda) 5, 407–415.
-
(2015)
G3 (Bethesda)
, vol.5
, pp. 407-415
-
-
Vouillot, L.1
Thelie, A.2
Pollet, N.3
-
54
-
-
84877707375
-
One-step generation of mice carrying mutations in multiple genes by CRISPR/Cas-mediated genome engineering
-
Wang, H.Y., Yang, H., Shivalila, C.S., Dawlaty, M.M., Cheng, A.W., Zhang, F. & Jaenisch, R. (2013) One-step generation of mice carrying mutations in multiple genes by CRISPR/Cas-mediated genome engineering. Cell 153, 910–918.
-
(2013)
Cell
, vol.153
, pp. 910-918
-
-
Wang, H.Y.1
Yang, H.2
Shivalila, C.S.3
Dawlaty, M.M.4
Cheng, A.W.5
Zhang, F.6
Jaenisch, R.7
-
55
-
-
84959354962
-
Off-target effects in CRISPR/Cas9-mediated genome engineering
-
Zhang, X.H., Tee, L.Y., Wang, X.G., Huang, Q.S. & Yang, S.H. (2015) Off-target effects in CRISPR/Cas9-mediated genome engineering. Mol. Ther. Nucleic Acids 4, e264.
-
(2015)
Mol. Ther. Nucleic Acids
, vol.4
-
-
Zhang, X.H.1
Tee, L.Y.2
Wang, X.G.3
Huang, Q.S.4
Yang, S.H.5
-
56
-
-
84923229919
-
An efficient genotyping method for genome-modified animals and human cells generated with CRISPR/Cas9 system
-
Zhu, X.X., Xu, Y.J., Yu, S.S., Lu, L., Ding, M.Q., Cheng, J., Song, G.X., Gao, X., Yao, L.M., Fan, D.D., Meng, S., Zhang, X.W., Hu, S.D. & Tian, Y. (2014) An efficient genotyping method for genome-modified animals and human cells generated with CRISPR/Cas9 system. Sci. Rep. 4, 6420.
-
(2014)
Sci. Rep.
, vol.4
, pp. 6420
-
-
Zhu, X.X.1
Xu, Y.J.2
Yu, S.S.3
Lu, L.4
Ding, M.Q.5
Cheng, J.6
Song, G.X.7
Gao, X.8
Yao, L.M.9
Fan, D.D.10
Meng, S.11
Zhang, X.W.12
Hu, S.D.13
Tian, Y.14
|