-
1
-
-
85019292458
-
Malignant astrocytomas originate from neural stem/progenitor cells in a somatic tumor suppressor mouse model
-
Alcantara Llaguno, S., Chen, J., Kwon, C.-H., Jackson, E. L., Li, Y., Burns, D. K., Alvarez-Buylla, A. and Parada, L. F. (2015). Malignant Astrocytomas Originate from Neural Stem/Progenitor Cells in a Somatic Tumor Suppressor Mouse Model. Cancer Cell 28, 429-440.
-
(2015)
Cancer Cell
, vol.28
, pp. 429-440
-
-
Alcantara Llaguno, S.1
Chen, J.2
Kwon, C.-H.3
Jackson, E.L.4
Li, Y.5
Burns, D.K.6
Alvarez-Buylla, A.7
Parada, L.F.8
-
2
-
-
84871846692
-
WNT signalling pathways as therapeutic targets in cancer
-
Anastas, J. N. and Moon, R. T. (2013). WNT signalling pathways as therapeutic targets in cancer. Nat. Rev. Cancer 13, 11-26.
-
(2013)
Nat. Rev. Cancer
, vol.13
, pp. 11-26
-
-
Anastas, J.N.1
Moon, R.T.2
-
3
-
-
80051531363
-
Notch signaling: Simplicity in design, versatility in function
-
Andersson, E. R., Sandberg, R. and Lendahl, U. (2011). Notch signaling: Simplicity in design, versatility in function. Development 138, 3593-3612.
-
(2011)
Development
, vol.138
, pp. 3593-3612
-
-
Andersson, E.R.1
Sandberg, R.2
Lendahl, U.3
-
4
-
-
84886859638
-
Chromatin dynamics during cellular reprogramming
-
Apostolou, E. and Hochedlinger, K. (2013). Chromatin dynamics during cellular reprogramming. Nature 502, 462-471.
-
(2013)
Nature
, vol.502
, pp. 462-471
-
-
Apostolou, E.1
Hochedlinger, K.2
-
5
-
-
0030829653
-
Efficiency of recombination by Cre transient expression in embryonic stem cells: Comparison of various promoters
-
Araki, K., Imaizumi, T., Okuyama, K., Oike, Y. and Yamamura, K.-I. (1997). Efficiency of recombination by Cre transient expression in embryonic stem cells: Comparison of various promoters. J. Biochem. 122, 977-982.
-
(1997)
J. Biochem.
, vol.122
, pp. 977-982
-
-
Araki, K.1
Imaizumi, T.2
Okuyama, K.3
Oike, Y.4
Yamamura, K.-I.5
-
6
-
-
33746650621
-
Hedgehog signalling in skin development and cancer
-
Athar, M., Tang, X., Lee, J. L., Kopelovich, L. and Kim, A. L. (2006). Hedgehog signalling in skin development and cancer. Exp. Dermatol. 15, 667-677.
-
(2006)
Exp. Dermatol.
, vol.15
, pp. 667-677
-
-
Athar, M.1
Tang, X.2
Lee, J.L.3
Kopelovich, L.4
Kim, A.L.5
-
7
-
-
84877149088
-
Notch signaling in pancreatic cancer: Oncogene or tumor suppressor?
-
Avila, J. L. and Kissil, J. L. (2013). Notch signaling in pancreatic cancer: Oncogene or tumor suppressor? Trends Mol. Med. 19, 320-327.
-
(2013)
Trends Mol. Med.
, vol.19
, pp. 320-327
-
-
Avila, J.L.1
Kissil, J.L.2
-
8
-
-
84883775911
-
ETV4 promotes metastasis in response to activation of PI3-kinase and Ras signaling in a mouse model of advanced prostate cancer
-
Aytes, A.,Mitrofanova,A., Kinkade, C.W.,Lefebvre, C.,Lei,M.,Phelan,V.,LeKaye, H. C., Koutcher, J. A., Cardiff, R. D., Califano, A. et al. (2013). ETV4 promotes metastasis in response to activation of PI3-kinase and Ras signaling in a mouse model of advanced prostate cancer. Proc. Natl. Acad. Sci. USA 110, E3506-E3515.
-
(2013)
Proc. Natl. Acad. Sci. USA
, vol.110
, pp. 3506-3515
-
-
Aytes, A.1
Mitrofanova, A.2
Kinkade, C.W.3
Lefebvre, C.4
Lei, M.5
Phelan, V.6
Le Kaye, H.C.7
Koutcher, J.A.8
Cardiff, R.D.9
Califano, A.10
-
9
-
-
58149143021
-
Sonic hedgehog promotes desmoplasia in pancreatic cancer
-
Bailey, J. M., Swanson, B. J., Hamada, T., Eggers, J. P., Singh, P. K., Caffery, T., Ouellette, M. M. and Hollingsworth, M. A. (2008). Sonic hedgehog promotes desmoplasia in pancreatic cancer. Clin. Cancer Res. 14, 5995-6004.
-
(2008)
Clin. Cancer Res.
, vol.14
, pp. 5995-6004
-
-
Bailey, J.M.1
Swanson, B.J.2
Hamada, T.3
Eggers, J.P.4
Singh, P.K.5
Caffery, T.6
Ouellette, M.M.7
Hollingsworth, M.A.8
-
10
-
-
70349974840
-
Sonic hedgehog paracrine signaling regulates metastasis and lymphangiogenesis in pancreatic cancer
-
Bailey, J. M., Mohr, A. M. and Hollingsworth, M. A. (2009). Sonic hedgehog paracrine signaling regulates metastasis and lymphangiogenesis in pancreatic cancer. Oncogene 28, 3513-3525.
-
(2009)
Oncogene
, vol.28
, pp. 3513-3525
-
-
Bailey, J.M.1
Mohr, A.M.2
Hollingsworth, M.A.3
-
11
-
-
35548974423
-
Identification of stem cells in small intestine and colon by marker gene Lgr5
-
Barker, N., Van Es, J. H., Kuipers, J., Kujala, P., Van Den Born, M., Cozijnsen, M., Haegebarth, A., Korving, J., Begthel, H., Peters, P. J. et al. (2007). Identification of stem cells in small intestine and colon by marker gene Lgr5. Nature 449, 1003-1007.
-
(2007)
Nature
, vol.449
, pp. 1003-1007
-
-
Barker, N.1
Van Es, J.H.2
Kuipers, J.3
Kujala, P.4
Van Den Born, M.5
Cozijnsen, M.6
Haegebarth, A.7
Korving, J.8
Begthel, H.9
Peters, P.J.10
-
12
-
-
59049106578
-
Crypt stem cells as the cells-of-origin of intestinal cancer
-
Barker, N.,Ridgway,R.A., Van Es, J. H., Van deWetering,M., Begthel, H., Van Den Born, M., Danenberg, E., Clarke, A. R., Sansom, O. J. and Clevers, H. (2009). Crypt stem cells as the cells-of-origin of intestinal cancer. Nature 457, 608-611.
-
(2009)
Nature
, vol.457
, pp. 608-611
-
-
Barker, N.1
Ridgway, R.A.2
Van Es, J.H.3
Van De Wetering, M.4
Begthel, H.5
Van Den Born, M.6
Danenberg, E.7
Clarke, A.R.8
Sansom, O.J.9
Clevers, H.10
-
13
-
-
13244256870
-
Origins and molecular pathology of ovarian cancer
-
Bell, D. A. (2005). Origins and molecular pathology of ovarian cancer. Mod. Pathol. 18, S19-S32.
-
(2005)
Mod. Pathol.
, vol.18
, pp. S19-S32
-
-
Bell, D.A.1
-
14
-
-
0028986154
-
Rhombomeric origin and rostrocaudal reassortment of neural crest cells revealed by intravital microscopy
-
Birgbauer, E., Sechrist, J., Bronnerfraser, M. and Fraser, S. (1995). Rhombomeric origin and rostrocaudal reassortment of neural crest cells revealed by intravital microscopy. Development 121, 935-945.
-
(1995)
Development
, vol.121
, pp. 935-945
-
-
Birgbauer, E.1
Sechrist, J.2
Bronnerfraser, M.3
Fraser, S.4
-
15
-
-
34250867977
-
Notch signaling in development and cancer
-
Bolo?s, V., Grego-Bessa, J. and De La Pompa, J. L. (2007). Notch signaling in development and cancer. Endocr. Rev. 28, 339-363.
-
(2007)
Endocr. Rev.
, vol.28
, pp. 339-363
-
-
Bolos, V.1
Grego-Bessa, J.2
De La Pompa, J.L.3
-
16
-
-
33747623018
-
Notch signalling: A simple pathway becomes complex
-
Bray, S. J. (2006). Notch signalling: A simple pathway becomes complex. Nat. Rev. Mol. Cell Biol. 7, 678-689.
-
(2006)
Nat. Rev. Mol. Cell Biol.
, vol.7
, pp. 678-689
-
-
Bray, S.J.1
-
17
-
-
84879414522
-
The mechanisms of Hedgehog signalling and its roles in development and disease
-
Briscoe, J. and The?rond, P. P. (2013). The mechanisms of Hedgehog signalling and its roles in development and disease. Nat. Rev. Mol. Cell Biol. 14, 416-429.
-
(2013)
Nat. Rev. Mol. Cell Biol.
, vol.14
, pp. 416-429
-
-
Briscoe, J.1
Therond, P.P.2
-
18
-
-
77955319729
-
The molecular regulation of vertebrate limb patterning
-
Butterfield, N. C., McGlinn, E. andWicking, C. (2010). The molecular regulation of vertebrate limb patterning. Curr. Top. Dev. Biol. 90, 319-341.
-
(2010)
Curr. Top. Dev. Biol.
, vol.90
, pp. 319-341
-
-
Butterfield, N.C.1
McGlinn, E.2
Wicking, C.3
-
19
-
-
79955558728
-
Second harmonic generation imaging microscopy: Applications to diseases diagnostics
-
Campagnola, P. (2011). Second harmonic generation imaging microscopy: Applications to diseases diagnostics. Anal. Chem. 83, 3224-3231.
-
(2011)
Anal. Chem.
, vol.83
, pp. 3224-3231
-
-
Campagnola, P.1
-
20
-
-
77953250105
-
Generation of iPSCs from cultured human malignant cells
-
Carette, J. E., Pruszak, J., Varadarajan, M., Blomen, V. A., Gokhale, S., Camargo, F. D., Wernig, M., Jaenisch, R. and Brummelkamp, T. R. (2010). Generation of iPSCs from cultured human malignant cells. Blood 115, 4039-4042.
-
(2010)
Blood
, vol.115
, pp. 4039-4042
-
-
Carette, J.E.1
Pruszak, J.2
Varadarajan, M.3
Blomen, V.A.4
Gokhale, S.5
Camargo, F.D.6
Wernig, M.7
Jaenisch, R.8
Brummelkamp, T.R.9
-
21
-
-
84924048076
-
Macrophages contribute to the cyclic activation of adult hair follicle stem cells
-
Castellana, D., Paus, R. and Perez-Moreno, M. (2014). Macrophages contribute to the cyclic activation of adult hair follicle stem cells. PLoS Biol. 12, e1002002.
-
(2014)
PLoS Biol.
, vol.12
, pp. e1002002
-
-
Castellana, D.1
Paus, R.2
Perez-Moreno, M.3
-
22
-
-
84865203983
-
A restricted cell population propagates glioblastoma growth after chemotherapy
-
Chen, J., Li, Y., Yu, T.-S., McKay, R. M., Burns, D. K., Kernie, S. G. and Parada, L. F. (2012). A restricted cell population propagates glioblastoma growth after chemotherapy. Nature 488, 522-526.
-
(2012)
Nature
, vol.488
, pp. 522-526
-
-
Chen, J.1
Li, Y.2
Yu, T.-S.3
McKay, R.M.4
Burns, D.K.5
Kernie, S.G.6
Parada, L.F.7
-
23
-
-
13344259902
-
The transcriptional control of trunk neural crest induction, survival, and delamination
-
Cheung, M., Chaboissier, M.-C., Mynett, A., Hirst, E., Schedl, A. and Briscoe, J. (2005). The transcriptional control of trunk neural crest induction, survival, and delamination. Dev. Cell 8, 179-192.
-
(2005)
Dev. Cell
, vol.8
, pp. 179-192
-
-
Cheung, M.1
Chaboissier, M.-C.2
Mynett, A.3
Hirst, E.4
Schedl, A.5
Briscoe, J.6
-
24
-
-
84863078902
-
Adult murine prostate basal and luminal cells are self-sustained lineages that can both serve as targets for prostate cancer initiation
-
Choi, N., Zhang, B., Zhang, L., Ittmann, M. and Xin, L. (2012). Adult murine prostate basal and luminal cells are self-sustained lineages that can both serve as targets for prostate cancer initiation. Cancer Cell 21, 253-265.
-
(2012)
Cancer Cell
, vol.21
, pp. 253-265
-
-
Choi, N.1
Zhang, B.2
Zhang, L.3
Ittmann, M.4
Xin, L.5
-
25
-
-
0035408007
-
FGF signaling regulates mesoderm cell fate specification and morphogenetic movement at the primitive streak
-
Ciruna, B. and Rossant, J. (2001). FGF signaling regulates mesoderm cell fate specification and morphogenetic movement at the primitive streak. Dev. Cell 1, 37-49.
-
(2001)
Dev. Cell
, vol.1
, pp. 37-49
-
-
Ciruna, B.1
Rossant, J.2
-
26
-
-
0034964418
-
The twohanded e box binding zinc finger protein SIP1 downregulates E-cadherin and induces invasion
-
Comijn, J., Berx, G., Vermassen, P., Verschueren, K., Van Grunsven, L., Bruyneel, E., Mareel, M., Huylebroeck, D. and Van Roy, F. (2001). The twohanded E box binding zinc finger protein SIP1 downregulates E-cadherin and induces invasion. Mol. Cell 7, 1267-1278.
-
(2001)
Mol. Cell
, vol.7
, pp. 1267-1278
-
-
Comijn, J.1
Berx, G.2
Vermassen, P.3
Verschueren, K.4
Van Grunsven, L.5
Bruyneel, E.6
Mareel, M.7
Huylebroeck, D.8
Van Roy, F.9
-
27
-
-
0023107421
-
Fate map for the 32-cell stage of Xenopus- Laevis
-
Dale, L. and Slack, J. M. W. (1987). Fate map for the 32-cell stage of Xenopus- Laevis. Development 99, 527-551.
-
(1987)
Development
, vol.99
, pp. 527-551
-
-
Dale, L.1
Slack, J.M.W.2
-
28
-
-
84863621527
-
Cancer epigenetics: Frommechanism to therapy
-
Dawson, M. A. and Kouzarides, T. (2012). Cancer epigenetics: Frommechanism to therapy. Cell 150, 12-27.
-
(2012)
Cell
, vol.150
, pp. 12-27
-
-
Dawson, M.A.1
Kouzarides, T.2
-
29
-
-
21244479003
-
Essential role of non-canonical Wnt signalling in neural crest migration
-
De Calisto, J., Araya, C., Marchant, L., Riaz, C. F. and Mayor, R. (2005). Essential role of non-canonical Wnt signalling in neural crest migration. Development 132, 2587-2597.
-
(2005)
Development
, vol.132
, pp. 2587-2597
-
-
De Calisto, J.1
Araya, C.2
Marchant, L.3
Riaz, C.F.4
Mayor, R.5
-
30
-
-
22244432840
-
The transcription factor snail induces tumor cell invasion through modulation of the epithelial cell differentiation program
-
De Craene, B., Gilbert, B., Stove, C., Bruyneel, E., Van Roy, F. and Berx, G. (2005). The transcription factor snail induces tumor cell invasion through modulation of the epithelial cell differentiation program. Cancer Res. 65, 6237-6244.
-
(2005)
Cancer Res.
, vol.65
, pp. 6237-6244
-
-
De Craene, B.1
Gilbert, B.2
Stove, C.3
Bruyneel, E.4
Van Roy, F.5
Berx, G.6
-
31
-
-
66149123318
-
Notch signaling in bulge stem cells is not required for selection of hair follicle fate
-
Demehri, S. and Kopan, R. (2009). Notch signaling in bulge stem cells is not required for selection of hair follicle fate. Development 136, 891-896.
-
(2009)
Development
, vol.136
, pp. 891-896
-
-
Demehri, S.1
Kopan, R.2
-
32
-
-
78751639675
-
A Cre-reporter transgenic mouse expressing the Far-red fluorescent protein katushka
-
Dieguez-Hurtado, R., Martín, J., Martínez-Corral, I., Martínez, M. D., Megas, D., Olmeda, D. and Ortega, S. (2011). A Cre-reporter transgenic mouse expressing the Far-red fluorescent protein katushka. Genesis 49, 36-45.
-
(2011)
Genesis
, vol.49
, pp. 36-45
-
-
Dieguez-Hurtado, R.1
Martín, J.2
Martínez-Corral, I.3
Martínez, M.D.4
Megas, D.5
Olmeda, D.6
Ortega, S.7
-
33
-
-
85019304190
-
Control of neural crest cell fate by the Wnt signaling pathway
-
Dorsky, R. I., Yang-Snyder, J., Moon, R. T. and Raible, D. W. (1998). Control of neural crest cell fate by the Wnt signaling pathway. Dev. Biol. 198, 179-179.
-
(1998)
Dev. Biol.
, vol.198
, pp. 179
-
-
Dorsky, R.I.1
Yang-Snyder, J.2
Moon, R.T.3
Raible, D.W.4
-
34
-
-
84865222310
-
Defining the mode of tumour growth by clonal analysis
-
Driessens, G., Beck, B., Caauwe, A., Simons, B. D. and Blanpain, C. (2012). Defining the mode of tumour growth by clonal analysis. Nature 488, 527-530.
-
(2012)
Nature
, vol.488
, pp. 527-530
-
-
Driessens, G.1
Beck, B.2
Caauwe, A.3
Simons, B.D.4
Blanpain, C.5
-
35
-
-
0029767838
-
Ligand-activated site-specific recombination in mice
-
Feil, R., Brocard, J., Mascrez, B., LeMeur, M., Metzger, D. and Chambon, P. (1996). Ligand-activated site-specific recombination in mice. Proc. Natl. Acad. Sci. USA 93, 10887-10890.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 10887-10890
-
-
Feil, R.1
Brocard, J.2
Mascrez, B.3
LeMeur, M.4
Metzger, D.5
Chambon, P.6
-
36
-
-
84877810500
-
Caught in the act: Revealing the metastatic process by live imaging
-
Fein, M. R. and Egeblad, M. (2013). Caught in the act: Revealing the metastatic process by live imaging. Dis. Model. Mech. 6, 580-593.
-
(2013)
Dis. Model. Mech.
, vol.6
, pp. 580-593
-
-
Fein, M.R.1
Egeblad, M.2
-
37
-
-
84875220633
-
Epidermal Wnt controls hair follicle induction by orchestrating dynamic signaling crosstalk between the epidermis and dermis
-
Fu, J. and Hsu, W. (2013). Epidermal Wnt controls hair follicle induction by orchestrating dynamic signaling crosstalk between the epidermis and dermis. J. Invest. Dermatol. 133, 890-898.
-
(2013)
J. Invest. Dermatol.
, vol.133
, pp. 890-898
-
-
Fu, J.1
Hsu, W.2
-
38
-
-
84919458472
-
Use of human embryonic stem cells to model pediatric gliomas with H3.3K27M histone mutation
-
Funato, K., Major, T., Lewis, P.W., Allis, C. D. and Tabar, V. (2014). Use of human embryonic stem cells to model pediatric gliomas with H3.3K27M histone mutation. Science 346, 1529-1533.
-
(2014)
Science
, vol.346
, pp. 1529-1533
-
-
Funato, K.1
Major, T.2
Lewis, P.W.3
Allis, C.D.4
Tabar, V.5
-
39
-
-
0038359353
-
Caught up in a Wnt storm: Wnt signaling in cancer
-
Giles, R. H., Van Es, J. H. and Clevers, H. (2003). Caught up in a Wnt storm: Wnt signaling in cancer. Biochim. Biophys. Acta 1653, 1-24.
-
(2003)
Biochim. Biophys. Acta
, vol.1653
, pp. 1-24
-
-
Giles, R.H.1
Van Es, J.H.2
Clevers, H.3
-
40
-
-
84938773709
-
Evolutionary determinants of cancer
-
Greaves, M. (2015). Evolutionary determinants of cancer. Cancer Discov. 5, 806-820.
-
(2015)
Cancer Discov.
, vol.5
, pp. 806-820
-
-
Greaves, M.1
-
41
-
-
84905826038
-
Acute myeloid leukaemia: A paradigm for the clonal evolution of cancer?
-
Grove, C. S. and Vassilou, G. S (2014). Acute myeloid leukaemia: A paradigm for the clonal evolution of cancer? Dis. Model. Mech. 7, 941-951.
-
(2014)
Dis. Model. Mech.
, vol.7
, pp. 941-951
-
-
Grove, C.S.1
Vassilou, G.S.2
-
42
-
-
84894229721
-
Cell lineage tracing reveals a biliary origin of intrahepatic cholangiocarcinoma
-
Guest, R. V., Boulter, L., Kendall, T. J., Minnis-Lyons, S. E., Walker, R., Wigmore, S. J., Sansom, O. J. and Forbes, S. J. (2014). Cell lineage tracing reveals a biliary origin of intrahepatic cholangiocarcinoma. Cancer Res. 74, 1005-1010.
-
(2014)
Cancer Res.
, vol.74
, pp. 1005-1010
-
-
Guest, R.V.1
Boulter, L.2
Kendall, T.J.3
Minnis-Lyons, S.E.4
Walker, R.5
Wigmore, S.J.6
Sansom, O.J.7
Forbes, S.J.8
-
43
-
-
33751252276
-
Cancer metastasis: Building a framework
-
Gupta, G. P. and Massague?, J. (2006). Cancer metastasis: Building a framework. Cell 127, 679-695.
-
(2006)
Cell
, vol.127
, pp. 679-695
-
-
Gupta, G.P.1
Massague, J.2
-
44
-
-
0037086277
-
The SLUG zinc-finger protein represses E-cadherin in breast cancer
-
Hajra, K. M., Chen, D. Y. S. and Fearon, E. R. (2002). The SLUG zinc-finger protein represses E-cadherin in breast cancer. Cancer Res. 62, 1613-1618.
-
(2002)
Cancer Res.
, vol.62
, pp. 1613-1618
-
-
Hajra, K.M.1
Chen, D.Y.S.2
Fearon, E.R.3
-
45
-
-
0021764162
-
Site-specific recombination by the bacteriophage-P1 lox-Cre system - Cre-mediated synapsis of 2lox sites
-
Hamilton, D. L. and Abremski, K. (1984). Site-specific recombination by the bacteriophage-P1 lox-Cre system - Cre-mediated synapsis of 2lox sites. J. Mol. Biol. 178, 481-486.
-
(1984)
J. Mol. Biol.
, vol.178
, pp. 481-486
-
-
Hamilton, D.L.1
Abremski, K.2
-
46
-
-
53449094858
-
Back and forth between cell fate specification and movement during vertebrate gastrulation
-
Heisenberg, C.-P. and Solnica-Krezel, L. (2008). Back and forth between cell fate specification and movement during vertebrate gastrulation. Curr. Opin. Genet. Dev. 18, 311-316.
-
(2008)
Curr. Opin. Genet. Dev.
, vol.18
, pp. 311-316
-
-
Heisenberg, C.-P.1
Solnica-Krezel, L.2
-
47
-
-
84885463112
-
MADM-ML, a mouse genetic mosaic system with increased clonal efficiency
-
Henner, A., Ventura, P. B., Jiang, Y. and Zong, H. (2013). MADM-ML, a mouse genetic mosaic system with increased clonal efficiency. PLoS ONE 8, e77672.
-
(2013)
PLoS ONE
, vol.8
, pp. e77672
-
-
Henner, A.1
Ventura, P.B.2
Jiang, Y.3
Zong, H.4
-
48
-
-
84947026641
-
Hox5 genes regulate the Wnt2/2b-Bmp4-signaling axis during lung development
-
Hrycaj, S. M., Dye, B. R., Baker, N. C., Larsen, B. M., Burke, A. C., Spence, J. R. andWellik, D. M. (2015). Hox5 genes regulate the Wnt2/2b-Bmp4-signaling axis during lung development. Cell Rep. 12, 903-912.
-
(2015)
Cell Rep.
, vol.12
, pp. 903-912
-
-
Hrycaj, S.M.1
Dye, B.R.2
Baker, N.C.3
Larsen, B.M.4
Burke, A.C.5
Spence, J.R.6
Wellik, D.M.7
-
49
-
-
0035577854
-
Hedgehog signaling in animal development: Paradigms and principles
-
Ingham, P. W. and McMahon, A. P. (2001). Hedgehog signaling in animal development: Paradigms and principles. Genes Dev. 15, 3059-3087.
-
(2001)
Genes Dev.
, vol.15
, pp. 3059-3087
-
-
Ingham, P.W.1
McMahon, A.P.2
-
50
-
-
84920408160
-
The neural crest is a source of mesenchymal stem cells with specialized hematopoietic stem-cell-niche function
-
Isern, J., Garcia-Garcia, A., Martin, A. M., Arranz, L., Martin-Perez, D., Torroja, C., Sanchez-Cabo, F. and Mendez-Ferrer, S. (2014). The neural crest is a source of mesenchymal stem cells with specialized hematopoietic stem-cell-niche function. Elife doi:10.7554/eLife.03696.
-
(2014)
Elife
-
-
Isern, J.1
Garcia-Garcia, A.2
Martin, A.M.3
Arranz, L.4
Martin-Perez, D.5
Torroja, C.6
Sanchez-Cabo, F.7
Mendez-Ferrer, S.8
-
51
-
-
84871157346
-
Hyaluronan impairs vascular function and drug delivery in a mouse model of pancreatic cancer
-
Jacobetz, M. A., Chan, D. S., Neesse, A., Bapiro, T. E., Cook, N., Frese, K. K., Feig, C., Nakagawa, T., Caldwell, M. E., Zecchini, H. I. et al. (2013). Hyaluronan impairs vascular function and drug delivery in a mouse model of pancreatic cancer. Gut 62, 112-120.
-
(2013)
Gut
, vol.62
, pp. 112-120
-
-
Jacobetz, M.A.1
Chan, D.S.2
Neesse, A.3
Bapiro, T.E.4
Cook, N.5
Frese, K.K.6
Feig, C.7
Nakagawa, T.8
Caldwell, M.E.9
Zecchini, H.I.10
-
52
-
-
73849129203
-
Real-time imaging reveals the single steps of brain metastasis formation
-
Kienast, Y., von Baumgarten, L., Fuhrmann, M., Klinkert,W. E. F., Goldbrunner, R., Herms, J. and Winkler, F. (2010). Real-time imaging reveals the single steps of brain metastasis formation. Nat. Med. 16, 116-122.
-
(2010)
Nat. Med.
, vol.16
, pp. 116-122
-
-
Kienast, Y.1
Von Baumgarten, L.2
Fuhrmann, M.3
Klinkert, W.E.F.4
Goldbrunner, R.5
Herms, J.6
Winkler, F.7
-
53
-
-
77955449906
-
Epigenetic memory in induced pluripotent stem cells
-
Kim, K., Doi, A.,Wen, B., Ng, K., Zhao, R., Cahan, P., Kim, J., Aryee, M. J., Ji, H., Ehrlich, L. I. R. et al. (2010). Epigenetic memory in induced pluripotent stem cells. Nature 467, 285-290.
-
(2010)
Nature
, vol.467
, pp. 285-290
-
-
Kim, K.1
Doi, A.2
Wen, B.3
Ng, K.4
Zhao, R.5
Cahan, P.6
Kim, J.7
Aryee, M.J.8
Ji, H.9
Ehrlich, L.I.R.10
-
54
-
-
84879798872
-
An iPSC line from human pancreatic ductal adenocarcinoma undergoes early to invasive stages of pancreatic cancer progression
-
Kim, J., Hoffman, J. P., Alpaugh, R. K., Rhim, A. D., Reichert, M., Stanger, B., Furth, E. E., Sepulveda, A. R., Yuan, C.-X.,Won, K.-J. et al. (2013). An iPSC line from human pancreatic ductal adenocarcinoma undergoes early to invasive stages of pancreatic cancer progression. Cell Rep. 3, 2088-2099.
-
(2013)
Cell Rep.
, vol.3
, pp. 2088-2099
-
-
Kim, J.1
Hoffman, J.P.2
Alpaugh, R.K.3
Rhim, A.D.4
Reichert, M.5
Stanger, B.6
Furth, E.E.7
Sepulveda, A.R.8
Yuan, C.-X.9
Won, K.-J.10
-
55
-
-
0025270337
-
Origin and organization of the zebrafish fate map
-
Kimmel, C. B.,Warga, R. M. and Schilling, T. F. (1990). Origin and organization of the zebrafish fate map. Development 108, 581-594.
-
(1990)
Development
, vol.108
, pp. 581-594
-
-
Kimmel, B.1
Warga C, R.M.2
Schilling, T.F.3
-
56
-
-
84930943281
-
Functional analysis of a chromosomal deletion associated with myelodysplastic syndromes using isogenic human induced pluripotent stem cells
-
Kotini, A. G., Chang, C.-J., Boussaad, I., Delrow, J. J., Dolezal, E. K., Nagulapally, A. B., Perna, F., Fishbein, G. A., Klimek, V. M., Hawkins, R. D. et al. (2015). Functional analysis of a chromosomal deletion associated with myelodysplastic syndromes using isogenic human induced pluripotent stem cells. Nat. Biotechnol. 33, 646-655.
-
(2015)
Nat. Biotechnol.
, vol.33
, pp. 646-655
-
-
Kotini, A.G.1
Chang, C.-J.2
Boussaad, I.3
Delrow, J.J.4
Dolezal, E.K.5
Nagulapally, A.B.6
Perna, F.7
Fishbein, G.A.8
Klimek, V.M.9
Hawkins, R.D.10
-
57
-
-
84863505092
-
Generation of induced pluripotent stem cells from primary chronic myelogenous leukemia patient samples
-
Kumano, K., Arai, S., Hosoi, M., Taoka, K., Takayama, N., Otsu, M., Nagae, G., Ueda, K., Nakazaki, K., Kamikubo, Y. et al. (2012). Generation of induced pluripotent stem cells from primary chronic myelogenous leukemia patient samples. Blood 119, 6234-6242.
-
(2012)
Blood
, vol.119
, pp. 6234-6242
-
-
Kumano, K.1
Arai, S.2
Hosoi, M.3
Taoka, K.4
Takayama, N.5
Otsu, M.6
Nagae, G.7
Ueda, K.8
Nakazaki, K.9
Kamikubo, Y.10
-
58
-
-
80053332023
-
Pancreatic mesenchyme regulates epithelial organogenesis throughout development
-
Landsman, L., Nijagal, A., Whitchurch, T. J., VanderLaan, R. L., Zimmer, W. E., MacKenzie, T. C. and Hebrok, M. (2011). Pancreatic mesenchyme regulates epithelial organogenesis throughout development. PLoS Biol. 9, e1001143.
-
(2011)
PLoS Biol.
, vol.9
, pp. e1001143
-
-
Landsman, L.1
Nijagal, A.2
Whitchurch, T.J.3
VanderLaan, R.L.4
Zimmer, W.E.5
MacKenzie, T.C.6
Hebrok, M.7
-
59
-
-
0036039827
-
In vivo imaging of embryonic vascular development using transgenic zebrafish
-
Lawson, N. D. andWeinstein, B. M. (2002). In vivo imaging of embryonic vascular development using transgenic zebrafish. Dev. Biol. 248, 307-318.
-
(2002)
Dev. Biol.
, vol.248
, pp. 307-318
-
-
Lawson, N.D.1
Weinstein, B.M.2
-
60
-
-
84927155547
-
Modeling familial cancer with induced pluripotent stem cells
-
Lee, D.-F., Su, J., Kim, H. S., Chang, B., Papatsenko, D., Zhao, R., Yuan, Y., Gingold, J., Xia, W., Darr, H. et al. (2015). Modeling familial cancer with induced pluripotent stem cells. Cell 161, 240-254.
-
(2015)
Cell
, vol.161
, pp. 240-254
-
-
Lee, D.-F.1
Su, J.2
Kim, H.S.3
Chang, B.4
Papatsenko, D.5
Zhao, R.6
Yuan, Y.7
Gingold, J.8
Xia, W.9
Darr, H.10
-
61
-
-
0642343226
-
Stromal progenitors are important for patterning epithelial and mesenchymal cell types in the embryonic kidney
-
Levinson, R. and Mendelsohn, C. (2003). Stromal progenitors are important for patterning epithelial and mesenchymal cell types in the embryonic kidney. Semin. Cell Dev. Biol. 14, 225-231.
-
(2003)
Semin. Cell Dev. Biol.
, vol.14
, pp. 225-231
-
-
Levinson, R.1
Mendelsohn, C.2
-
62
-
-
84884817124
-
A Keratin 15 containing stem cell population from the hair follicle contributes to squamous papilloma development in the mouse
-
Li, S. L., Park, H., Trempus, C. S., Gordon, D., Liu, Y. P., Cotsarelis, G. and Morris, R. J. (2013). A Keratin 15 containing stem cell population from the hair follicle contributes to squamous papilloma development in the mouse. Mol. Carcinogen. 52, 751-759.
-
(2013)
Mol. Carcinogen.
, vol.52
, pp. 751-759
-
-
Li, S.L.1
Park, H.2
Trempus, C.S.3
Gordon, D.4
Liu, Y.P.5
Cotsarelis, G.6
Morris, R.J.7
-
63
-
-
84928092998
-
BMP-SHH signaling network controls epithelial stem cell fate via regulation of its niche in the developing tooth
-
Li, J., Feng, J., Liu, Y., Ho, T.-V., Grimes, W., Ho, H. A., Park, S., Wang, S. and Chai, Y. (2015). BMP-SHH signaling network controls epithelial stem cell fate via regulation of its niche in the developing tooth. Dev. Cell 33, 125-135.
-
(2015)
Dev. Cell
, vol.33
, pp. 125-135
-
-
Li, J.1
Feng, J.2
Liu, Y.3
Ho, T.-V.4
Grimes, W.5
Ho, H.A.6
Park, S.7
Wang, S.8
Chai, Y.9
-
64
-
-
79960809488
-
Mosaic analysis with double markers reveals tumor cell of origin in glioma
-
Liu, C., Sage, J. C., Miller, M. R., Verhaak, R. G. W., Hippenmeyer, S., Vogel, H., Foreman, O., Bronson, R. T., Nishiyama, A., Luo, L. Q. et al. (2011). Mosaic analysis with double markers reveals tumor cell of origin in glioma. Cell 146, 209-221.
-
(2011)
Cell
, vol.146
, pp. 209-221
-
-
Liu, C.1
Sage, J.C.2
Miller, M.R.3
Verhaak, R.G.W.4
Hippenmeyer, S.5
Vogel, H.6
Foreman, O.7
Bronson, R.T.8
Nishiyama, A.9
Luo, L.Q.10
-
65
-
-
0242690094
-
Lineage choice and differentiation in mouse embryos and embryonic stem cells
-
Loebel, D. A. F.,Watson, C. M., De Young, R. A. and Tam, P. P. L. (2003). Lineage choice and differentiation in mouse embryos and embryonic stem cells. Dev. Biol. 264, 1-14.
-
(2003)
Dev. Biol.
, vol.264
, pp. 1-14
-
-
Loebel, D.A.F.1
Watson, C.M.2
De Young, R.A.3
Tam, P.P.L.4
-
66
-
-
78650905135
-
Stabilized imaging of immune surveillance in the mouse lung
-
Looney, M. R., Thornton, E. E., Sen, D., Lamm, W. J., Glenny, R. W. and Krummel, M. F. (2011). Stabilized imaging of immune surveillance in the mouse lung. Nat. Methods 8, 91-96.
-
(2011)
Nat. Methods
, vol.8
, pp. 91-96
-
-
Looney, M.R.1
Thornton, E.E.2
Sen, D.3
Lamm, W.J.4
Glenny, R.W.5
Krummel, M.F.6
-
67
-
-
84921064232
-
Hypoxia induces pluripotency in primordial germ cells by HIF1alpha stabilization and Oct4 deregulation
-
Lo?pez-Iglesias, P., Alcaina, Y., Tapia, N., Sabour, D., Arauzo-Bravo, M. J., De La Maza, D. S., Berra, E.,O'Mara, A. N., Nistal, M., Ortega, S. et al. (2015). Hypoxia induces pluripotency in primordial germ cells by HIF1alpha stabilization and Oct4 deregulation. Antioxid. Redox Signal. 22, 205-223.
-
(2015)
Antioxid. Redox Signal.
, vol.22
, pp. 205-223
-
-
Lopez-Iglesias, P.1
Alcaina, Y.2
Tapia, N.3
Sabour, D.4
Arauzo-Bravo, M.J.5
De La Maza, D.S.6
Berra, E.7
O'Mara, A.N.8
Nistal, M.9
Ortega, S.10
-
68
-
-
84943327727
-
Pancreatic cancer metastases harbor evidence of polyclonality
-
Maddipati, R. and Stanger, B. (2015). Pancreatic Cancer Metastases Harbor Evidence of Polyclonality. Cancer Discov. 5, 1086-1097.
-
(2015)
Cancer Discov.
, vol.5
, pp. 1086-1097
-
-
Maddipati, R.1
Stanger, B.2
-
69
-
-
84908032167
-
Non-cell-autonomous driving of tumour growth supports subclonal heterogeneity
-
Marusyk, A., Tabassum, D. P., Altrock, P. M., Almendro, V., Michor, F. and Polyak, K. (2014). Non-cell-autonomous driving of tumour growth supports subclonal heterogeneity. Nature 514, 54-58.
-
(2014)
Nature
, vol.514
, pp. 54-58
-
-
Marusyk, A.1
Tabassum, D.P.2
Altrock, P.M.3
Almendro, V.4
Michor, F.5
Polyak, K.6
-
70
-
-
84870724358
-
In toto live imaging of mouse morphogenesis and new insights into neural tube closure
-
Massarwa, R. and Niswander, L. (2013). In toto live imaging of mouse morphogenesis and new insights into neural tube closure. Development 140, 226-236.
-
(2013)
Development
, vol.140
, pp. 226-236
-
-
Massarwa, R.1
Niswander, L.2
-
71
-
-
0030030888
-
Fate mapping study of the endoderm of the 1.5-day-old chick embryo
-
Matsushita, S. (1996). Fate mapping study of the endoderm of the 1.5-day-old chick embryo. Roux's Arch. Dev. Biol. 205, 225-231.
-
(1996)
Roux's Arch. Dev. Biol.
, vol.205
, pp. 225-231
-
-
Matsushita, S.1
-
72
-
-
76249133692
-
Defined factors induce reprogramming of gastrointestinal cancer cells
-
Miyoshi, N., Ishii, H., Nagai, K.-I., Hoshino, H., Mimori, K., Tanaka, F., Nagano, H., Sekimoto, M., Doki, Y. and Mori, M. (2010). Defined factors induce reprogramming of gastrointestinal cancer cells. Proc. Natl. Acad. Sci. USA 107, 40-45.
-
(2010)
Proc. Natl. Acad. Sci. USA
, vol.107
, pp. 40-45
-
-
Miyoshi, N.1
Ishii, H.2
Nagai, K.-I.3
Hoshino, H.4
Mimori, K.5
Tanaka, F.6
Nagano, H.7
Sekimoto, M.8
Doki, Y.9
Mori, M.10
-
73
-
-
34548175512
-
Signaling networks guiding epithelialmesenchymal transitions during embryogenesis and cancer progression
-
Moustakas, A. and Heldin, C.-H. (2007). Signaling networks guiding epithelialmesenchymal transitions during embryogenesis and cancer progression. Cancer Sci. 98, 1512-1520.
-
(2007)
Cancer Sci.
, vol.98
, pp. 1512-1520
-
-
Moustakas, A.1
Heldin, C.-H.2
-
74
-
-
0034059140
-
Cre recombinase: The universal reagent for genome tailoring
-
Nagy, A. (2000). Cre recombinase: The universal reagent for genome tailoring. Genesis 26, 99-109.
-
(2000)
Genesis
, vol.26
, pp. 99-109
-
-
Nagy, A.1
-
75
-
-
84859820567
-
Imaging tumor-stroma interactions during chemotherapy reveals contributions of the microenvironment to resistance
-
Nakasone, E. S., Askautrud, H. A., Kees, T., Park, J.-H., Plaks, V., Ewald, A. J., Fein, M., Rasch, M. G., Tan, Y.-X., Qiu, J. et al. (2012). Imaging tumor-stroma interactions during chemotherapy reveals contributions of the microenvironment to resistance. Cancer Cell 21, 488-503.
-
(2012)
Cancer Cell
, vol.21
, pp. 488-503
-
-
Nakasone, E.S.1
Askautrud, H.A.2
Kees, T.3
Park, J.-H.4
Plaks, V.5
Ewald, A.J.6
Fein, M.7
Rasch, M.G.8
Tan, Y.-X.9
Qiu, J.10
-
76
-
-
67149143399
-
Inhibition of hedgehog signaling enhances delivery of chemotherapy in a mouse model of pancreatic cancer
-
Olive, K. P., Jacobetz, M. A., Davidson, C. J., Gopinathan, A., McIntyre, D., Honess, D., Madhu, B., Goldgraben, M. A., Caldwell, M. E., Allard, D. et al. (2009). Inhibition of hedgehog signaling enhances delivery of chemotherapy in a mouse model of pancreatic cancer. Science 324, 1457-1461.
-
(2009)
Science
, vol.324
, pp. 1457-1461
-
-
Olive, K.P.1
Jacobetz, M.A.2
Davidson, C.J.3
Gopinathan, A.4
McIntyre, D.5
Honess, D.6
Madhu, B.7
Goldgraben, M.A.8
Caldwell, M.E.9
Allard, D.10
-
77
-
-
84902469661
-
Depletion of carcinoma-associated fibroblasts and fibrosis induces immunosuppression and accelerates pancreas cancer with reduced survival
-
O? zdemir, B. C., Pentcheva-Hoang, T., Carstens, J. L., Zheng, X., Wu, C.-C., Simpson, T. R., Laklai, H., Sugimoto, H., Kahlert, C., Novitskiy, S. V. et al. (2014). Depletion of carcinoma-associated fibroblasts and fibrosis induces immunosuppression and accelerates pancreas cancer with reduced survival. Cancer Cell 25, 719-734.
-
(2014)
Cancer Cell
, vol.25
, pp. 719-734
-
-
Ozdemir, B.C.1
Pentcheva-Hoang, T.2
Carstens, J.L.3
Zheng, X.4
Wu, C.-C.5
Simpson, T.R.6
Laklai, H.7
Sugimoto, H.8
Kahlert, C.9
Novitskiy, S.V.10
-
78
-
-
77957883342
-
The Hippo signaling pathway in development and cancer
-
Pan, D. (2010). The Hippo signaling pathway in development and cancer. Dev. Cell 19, 491-505.
-
(2010)
Dev. Cell
, vol.19
, pp. 491-505
-
-
Pan, D.1
-
79
-
-
84875125402
-
Epigenetics of reprogramming to induced pluripotency
-
Papp, B. and Plath, K. (2013). Epigenetics of reprogramming to induced pluripotency. Cell 152, 1324-1343.
-
(2013)
Cell
, vol.152
, pp. 1324-1343
-
-
Papp, B.1
Plath, K.2
-
80
-
-
34249289041
-
Snail, ZEB and bHLH factors in tumour progression: An alliance against the epithelial phenotype?
-
Peinado, H., Olmeda, D. and Cano, A. (2007). Snail, ZEB and bHLH factors in tumour progression: An alliance against the epithelial phenotype? Nat. Rev. Cancer 7, 415-428.
-
(2007)
Nat. Rev. Cancer
, vol.7
, pp. 415-428
-
-
Peinado, H.1
Olmeda, D.2
Cano, A.3
-
81
-
-
71149111905
-
Wnt signaling and the polarity of the primary body axis
-
Petersen, C. P. and Reddien, P. W. (2009). Wnt signaling and the polarity of the primary body axis. Cell 139, 1056-1068.
-
(2009)
Cell
, vol.139
, pp. 1056-1068
-
-
Petersen, C.P.1
Reddien, P.W.2
-
82
-
-
33846193290
-
The many ways of Wnt in cancer
-
Polakis, P. (2007). The many ways of Wnt in cancer. Curr. Opin. Genet. Dev. 17, 45-51.
-
(2007)
Curr. Opin. Genet. Dev.
, vol.17
, pp. 45-51
-
-
Polakis, P.1
-
83
-
-
84858602107
-
Enzymatic targeting of the Stroma ablates physical barriers to treatment of pancreatic ductal adenocarcinoma
-
Provenzano, P. P., Cuevas, C., Chang, A. E., Goel, V. K., Von Hoff, D. D. and Hingorani, S. R. (2012). Enzymatic targeting of the Stroma ablates physical barriers to treatment of pancreatic ductal adenocarcinoma. Cancer Cell 21, 418-429.
-
(2012)
Cancer Cell
, vol.21
, pp. 418-429
-
-
Provenzano, P.P.1
Cuevas, C.2
Chang, A.E.3
Goel, V.K.4
Von Hoff, D.D.5
Hingorani, S.R.6
-
84
-
-
0142259346
-
The role of Notch in tumorigenesis: Oncogene or tumour suppressor?
-
Radtke, F. and Raj, K. (2003). The role of Notch in tumorigenesis: Oncogene or tumour suppressor? Nat. Rev. Cancer 3, 756-767.
-
(2003)
Nat. Rev. Cancer
, vol.3
, pp. 756-767
-
-
Radtke, F.1
Raj, K.2
-
85
-
-
84860517655
-
IPSCs from cancer cells: Challenges and opportunities
-
Ramos-Mejia, V., Fraga, M. F. and Menendez, P. (2012). iPSCs from cancer cells: Challenges and opportunities. Trends Mol. Med. 18, 245-247.
-
(2012)
Trends Mol. Med.
, vol.18
, pp. 245-247
-
-
Ramos-Mejia, V.1
Fraga, M.F.2
Menendez, P.3
-
86
-
-
84856088337
-
EMT and dissemination precede pancreatic tumor formation
-
Rhim, A. D., Mirek, E. T., Aiello, N. M., Maitra, A., Bailey, J. M., McAllister, F., Reichert, M., Beatty, G. L., Rustgi, A. K., Vonderheide, R. H. et al. (2012). EMT and dissemination precede pancreatic tumor formation. Cell 148, 349-361.
-
(2012)
Cell
, vol.148
, pp. 349-361
-
-
Rhim, A.D.1
Mirek, E.T.2
Aiello, N.M.3
Maitra, A.4
Bailey, J.M.5
McAllister, F.6
Reichert, M.7
Beatty, G.L.8
Rustgi, A.K.9
Vonderheide, R.H.10
-
87
-
-
84902435628
-
Stromal elements act to restrain, rather than support, pancreatic ductal adenocarcinoma
-
Rhim, A. D., Oberstein, P. E., Thomas, D. H., Mirek, E. T., Palermo, C. F., Sastra, S. A., Dekleva, E. N., Saunders, T., Becerra, C. P., Tattersa, I. W. et al. (2014). Stromal elements act to restrain, rather than support, pancreatic ductal adenocarcinoma. Cancer Cell 25, 735-747.
-
(2014)
Cancer Cell
, vol.25
, pp. 735-747
-
-
Rhim, A.D.1
Oberstein, P.E.2
Thomas, D.H.3
Mirek, E.T.4
Palermo, C.F.5
Sastra, S.A.6
Dekleva, E.N.7
Saunders, T.8
Becerra, C.P.9
Tattersa, I.W.10
-
88
-
-
84940102321
-
An orthotopic glioblastoma mouse model maintaining brain parenchymal physical constraints and suitable for intravital two-photon microscopy
-
Ricard, C., Stanchi, F., Rougon, G. and Debarbieux, F. (2014). An orthotopic glioblastoma mouse model maintaining brain parenchymal physical constraints and suitable for intravital two-photon microscopy. J. Vis. Exp. doi:10.3791/51108.
-
(2014)
J. Vis. Exp.
-
-
Ricard, C.1
Stanchi, F.2
Rougon, G.3
Debarbieux, F.4
-
89
-
-
84868269173
-
Intravital microscopy through an abdominal imaging window reveals a pre-micrometastasis stage during liver metastasis
-
Ritsma, L., Steller, E. J. A., Beerling, E., Loomans, C. J. M., Zomer, A., Gerlach, C., Vrisekoop, N., Seinstra, D., Van Gurp, L., Schafer, R. et al. (2012). Intravital microscopy through an abdominal imaging window reveals a pre-micrometastasis stage during liver metastasis. Sci. Transl. Med. 4, 158ra145.
-
(2012)
Sci. Transl. Med.
, vol.4
, pp. 158-165
-
-
Ritsma, L.1
Steller, E.J.A.2
Beerling, E.3
Loomans, C.J.M.4
Zomer, A.5
Gerlach, C.6
Vrisekoop, N.7
Seinstra, D.8
Van Gurp, L.9
Schafer, R.10
-
90
-
-
0024041732
-
Site-specific DNA recombination in mammalian cells by the Cre recombinase of bacteriophage P1
-
Sauer, B. and Henderson, N. (1988). Site-specific DNA recombination in mammalian cells by the Cre recombinase of bacteriophage P1. Proc. Natl. Acad. Sci. USA 85, 5166-5170.
-
(1988)
Proc. Natl. Acad. Sci. USA
, vol.85
, pp. 5166-5170
-
-
Sauer, B.1
Henderson, N.2
-
91
-
-
84864854371
-
Lineage tracing reveals Lgr5(+) stem cell activity in mouse intestinal adenomas
-
Schepers, A. G., Snippert, H. J., Stange, D. E., Van Den Born, M., Van Es, J. H., Van De Wetering, M. and Clevers, H. (2012). Lineage tracing reveals Lgr5(+) stem cell activity in mouse intestinal adenomas. Science 337, 730-735.
-
(2012)
Science
, vol.337
, pp. 730-735
-
-
Schepers, A.G.1
Snippert, H.J.2
Stange, D.E.3
Van Den Born, M.4
Van Es, J.H.5
Van De Wetering, M.6
Clevers, H.7
-
92
-
-
84900384372
-
Children are not just little adults: Recent advances in understanding of diffuse intrinsic pontine glioma biology
-
Schroeder, K. M., Hoeman, C. M. and Becher, O. J. (2014). Children are not just little adults: Recent advances in understanding of diffuse intrinsic pontine glioma biology. Pediatr. Res. 75, 205-209.
-
(2014)
Pediatr. Res.
, vol.75
, pp. 205-209
-
-
Schroeder, K.M.1
Hoeman, C.M.2
Becher, O.J.3
-
94
-
-
77957223906
-
Intestinal crypt homeostasis results from neutral competition between symmetrically dividing Lgr5 stem cells
-
Snippert, H. J., Van Der Flier, L. G., Sato, T., Van Es, J. H., Van Den Born, M., Kroon-Veenboer, C., Barker, N., Klein, A. M., Van Rheenen, J., Simons, B. D. et al. (2010). Intestinal crypt homeostasis results from neutral competition between symmetrically dividing Lgr5 stem cells. Cell 143, 134-144.
-
(2010)
Cell
, vol.143
, pp. 134-144
-
-
Snippert, H.J.1
Van Der Flier, L.G.2
Sato, T.3
Van Es, J.H.4
Van Den Born, M.5
Kroon-Veenboer, C.6
Barker, N.7
Klein, A.M.8
Van Rheenen, J.9
Simons, B.D.10
-
95
-
-
80053063127
-
Maintaining embryonic stem cell pluripotency with Wnt signaling
-
Sokol, S. Y. (2011). Maintaining embryonic stem cell pluripotency with Wnt signaling. Development 138, 4341-4350.
-
(2011)
Development
, vol.138
, pp. 4341-4350
-
-
Sokol, S.Y.1
-
96
-
-
0019888368
-
Bacteriophage-P1 site-specific recombination .2. Recombination between loxp and the bacterial chromosome
-
Sternberg, N., Hamilton, D. and Hoess, R. (1981). Bacteriophage-P1 site-specific recombination .2. recombination between loxp and the bacterial chromosome. J. Mol. Biol. 150, 487-507.
-
(1981)
J. Mol. Biol.
, vol.150
, pp. 487-507
-
-
Sternberg, N.1
Hamilton, D.2
Hoess, R.3
-
97
-
-
84875340771
-
Widespread resetting of DNA methylation in glioblastoma-initiating cells suppresses malignant cellular behavior in a lineage-dependent manner
-
Stricker, S. H., Feber, A., Engstrom, P. G., Caren, H., Kurian, K. M., Takashima, Y., Watts, C., Way, M., Dirks, P., Bertone, P. et al. (2013). Widespread resetting of DNA methylation in glioblastoma-initiating cells suppresses malignant cellular behavior in a lineage-dependent manner. Genes Dev. 27, 654-669.
-
(2013)
Genes Dev.
, vol.27
, pp. 654-669
-
-
Stricker, S.H.1
Feber, A.2
Engstrom, P.G.3
Caren, H.4
Kurian, K.M.5
Takashima, Y.6
Watts, C.7
Way, M.8
Dirks, P.9
Bertone, P.10
-
98
-
-
0036233040
-
Role of basic fibroblast growth factor-2 in epithelialmesenchymal transformation
-
Strutz, F., Zeisberg, M., Ziyadeh, F. N., Yang, C.-Q., Kalluri, R., Muller, G. A. and Neilson, E. G. (2002). Role of basic fibroblast growth factor-2 in epithelialmesenchymal transformation. Kidney Int. 61, 1714-1728.
-
(2002)
Kidney Int.
, vol.61
, pp. 1714-1728
-
-
Strutz, F.1
Zeisberg, M.2
Ziyadeh, F.N.3
Yang, C.-Q.4
Kalluri, R.5
Muller, G.A.6
Neilson, E.G.7
-
99
-
-
84937970942
-
Tumorigenesis: It takes a village
-
Tabassum, D. P. and Polyak, K. (2015). Tumorigenesis: It takes a village. Nat. Rev. Cancer 15, 473-483.
-
(2015)
Nat. Rev. Cancer
, vol.15
, pp. 473-483
-
-
Tabassum, D.P.1
Polyak, K.2
-
100
-
-
33747195353
-
Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors
-
Takahashi, K. and Yamanaka, S. (2006). Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell 126, 663-676.
-
(2006)
Cell
, vol.126
, pp. 663-676
-
-
Takahashi, K.1
Yamanaka, S.2
-
101
-
-
0030815478
-
Signalling networks regulating dental development
-
Thesleff, I. and Sharpe, P. (1997). Signalling networks regulating dental development. Mech. Dev. 67, 111-123.
-
(1997)
Mech. Dev.
, vol.67
, pp. 111-123
-
-
Thesleff, I.1
Sharpe, P.2
-
102
-
-
63149124772
-
Hedgehog signaling is restricted to the stromal compartment during pancreatic carcinogenesis
-
Tian, H., Callahan, C. A., DuPree, K. J., Darbonne,W. C., Ahn, C. P., Scales, S. J. and De Sauvage, F. J. (2009). Hedgehog signaling is restricted to the stromal compartment during pancreatic carcinogenesis. Proc. Natl. Acad. Sci. USA 106, 4254-4259.
-
(2009)
Proc. Natl. Acad. Sci. USA
, vol.106
, pp. 4254-4259
-
-
Tian, H.1
Callahan, C.A.2
DuPree, K.J.3
Darbonne, W.C.4
Ahn, C.P.5
Scales, S.J.6
De Sauvage, F.J.7
-
103
-
-
84921454164
-
Functional reprogramming of polyploidization in megakaryocytes
-
Trakala, M., Rodrguez-Acebes, S., Maroto, M., Symonds, C. E., Santamara, D., Ortega, S., Barbacid, M., Me?ndez, J. and Malumbres, M. (2015). Functional reprogramming of polyploidization in megakaryocytes. Dev. Cell 32, 155-167.
-
(2015)
Dev. Cell
, vol.32
, pp. 155-167
-
-
Trakala, M.1
Rodrguez-Acebes, S.2
Maroto, M.3
Symonds, C.E.4
Santamara, D.5
Ortega, S.6
Barbacid, M.7
Mendez, J.8
Malumbres, M.9
-
104
-
-
36849036401
-
Morphogens and the control of cell proliferation and patterning in the spinal cord
-
Ulloa, F. and Briscoe, J. (2007). Morphogens and the control of cell proliferation and patterning in the spinal cord. Cell Cycle 6, 2640-2649.
-
(2007)
Cell Cycle
, vol.6
, pp. 2640-2649
-
-
Ulloa, F.1
Briscoe, J.2
-
105
-
-
80051474342
-
A simple introduction to multiphoton microscopy
-
Ustione, A. and Piston, D. W. (2011). A simple introduction to multiphoton microscopy. J. Microsc. 243, 221-226.
-
(2011)
J. Microsc.
, vol.243
, pp. 221-226
-
-
Ustione, A.1
Piston, D.W.2
-
106
-
-
70350380887
-
Sox2 is dispensable for the reprogramming of melanocytes and melanoma cells into induced pluripotent stem cells
-
Utikal, J., Maherali, N., Kulalert, W. and Hochedlinger, K. (2009). Sox2 is dispensable for the reprogramming of melanocytes and melanoma cells into induced pluripotent stem cells. J. Cell Sci. 122, 3502-3510.
-
(2009)
J. Cell Sci.
, vol.122
, pp. 3502-3510
-
-
Utikal, J.1
Maherali, N.2
Kulalert, W.3
Hochedlinger, K.4
-
107
-
-
84904264545
-
Quiescent Sox(2+) cells drive hierarchical growth and relapse in sonic hedgehog subgroup medulloblastoma
-
Vanner, R. J., Remke, M., Gallo, M., Selvadurai, H. J., Coutinho, F., Lee, L., Kushida, M., Head, R., Morrissy, S., Zhu, X. et al. (2014). Quiescent Sox(2+) cells drive hierarchical growth and relapse in sonic hedgehog subgroup medulloblastoma. Cancer Cell 26, 33-47.
-
(2014)
Cancer Cell
, vol.26
, pp. 33-47
-
-
Vanner, R.J.1
Remke, M.2
Gallo, M.3
Selvadurai, H.J.4
Coutinho, F.5
Lee, L.6
Kushida, M.7
Head, R.8
Morrissy, S.9
Zhu, X.10
-
108
-
-
0033557147
-
A general model for sitespecific recombination by the integrase family recombinases
-
Voziyanov, Y., Pathania, S. and Jayaram, M. (1999). A general model for sitespecific recombination by the integrase family recombinases. Nucleic Acids Res. 27, 930-941.
-
(1999)
Nucleic Acids Res.
, vol.27
, pp. 930-941
-
-
Voziyanov, Y.1
Pathania, S.2
Jayaram, M.3
-
109
-
-
78651467232
-
Basal cell carcinomas arise from hair follicle stem cells in Ptch1(+/?) mice
-
Wang, G. Y., Wang, J., Mancianti, M.-L. and Epstein, E. H. (2011). Basal cell carcinomas arise from hair follicle stem cells in Ptch1(+/?) mice. Cancer Cell 19, 114-124.
-
(2011)
Cancer Cell
, vol.19
, pp. 114-124
-
-
Wang, G.Y.1
Wang, J.2
Mancianti, M.-L.3
Epstein, E.H.4
-
110
-
-
84979282947
-
Dynamic relationship of the epithelium and mesenchyme during salivary gland initiation: The role of Fgf10
-
Wells, K. L., Gaete, M., Matalova, E., Deutsch, D., Rice, D. and Tucker, A. S. (2013). Dynamic relationship of the epithelium and mesenchyme during salivary gland initiation: The role of Fgf10. Biol. Open 2, 981-989.
-
(2013)
Biol. Open
, vol.2
, pp. 981-989
-
-
Wells, K.L.1
Gaete, M.2
Matalova, E.3
Deutsch, D.4
Rice, D.5
Tucker, A.S.6
-
111
-
-
34047246527
-
Direct visualization of macrophage-assisted tumor cell intravasation in mammary tumors
-
Wyckoff, J. B., Wang, Y., Lin, E. Y., Li, J.-F., Goswami, S., Stanley, E. R., Segall, J. E., Pollard, J. W. and Condeelis, J. (2007). Direct visualization of macrophage-assisted tumor cell intravasation in mammary tumors. Cancer Res. 67, 2649-2656.
-
(2007)
Cancer Res.
, vol.67
, pp. 2649-2656
-
-
Wyckoff, J.B.1
Wang, Y.2
Lin, E.Y.3
Li, J.-F.4
Goswami, S.5
Stanley, E.R.6
Segall, J.E.7
Pollard, J.W.8
Condeelis, J.9
-
112
-
-
2942707848
-
Twist, a master regulator of morphogenesis, plays an essential role in tumor metastasis
-
Yang, J., Mani, S. A., Donaher, J. L., Ramaswamy, S., Itzykson, R. A., Come, C., Savagner, P., Gitelman, I., Richardson, A. andWeinberg, R. A. (2004). Twist, a master regulator of morphogenesis, plays an essential role in tumor metastasis. Cell 117, 927-939.
-
(2004)
Cell
, vol.117
, pp. 927-939
-
-
Yang, J.1
Mani, S.A.2
Donaher, J.L.3
Ramaswamy, S.4
Itzykson, R.A.5
Come, C.6
Savagner, P.7
Gitelman, I.8
Richardson, A.9
Weinberg, R.A.10
-
113
-
-
70449805406
-
Vertebrate limb bud development: Moving towards integrative analysis of organogenesis
-
Zeller, R., Lo?pez-Ros, J. and Zuniga, A. (2009). Vertebrate limb bud development: Moving towards integrative analysis of organogenesis. Nat. Rev. Genet. 10, 845-858.
-
(2009)
Nat. Rev. Genet.
, vol.10
, pp. 845-858
-
-
Zeller, R.1
Lopez-Ros, J.2
Zuniga, A.3
-
114
-
-
84877574727
-
Terminal differentiation and loss of tumorigenicity of human cancers via pluripotency-based reprogramming
-
Zhang, X., Cruz, F. D., Terry, M., Remotti, F. and Matushansky, I. (2013). Terminal differentiation and loss of tumorigenicity of human cancers via pluripotency-based reprogramming. Oncogene 32, 2249-2260.
-
(2013)
Oncogene
, vol.32
, pp. 2249-2260
-
-
Zhang, X.1
Cruz, F.D.2
Terry, M.3
Remotti, F.4
Matushansky, I.5
-
115
-
-
84930225521
-
In vivo imaging reveals extracellular vesicle-mediated phenocopying of metastatic behavior
-
Zomer, A., Maynard, C., Verweij, F. J., Kamermans, A., Scha? fer, R., Beerling, E., Schiffelers, R. M., deWit, E., Berenguer, J., Ellenbroek, S. I. J. et al. (2015). In vivo imaging reveals extracellular vesicle-mediated phenocopying of metastatic behavior. Cell 161, 1046-1057.
-
(2015)
Cell
, vol.161
, pp. 1046-1057
-
-
Zomer, A.1
Maynard, C.2
Verweij, F.J.3
Kamermans, A.4
Schafer, R.5
Beerling, E.6
Schiffelers, R.M.7
De Wit, E.8
Berenguer, J.9
Ellenbroek, S.I.J.10
-
116
-
-
18844421090
-
Mosaic analysis with double markers in mice
-
Zong, H., Espinosa, J. S., Su, H. H., Muzumdar, M. D. and Luo, L. (2005). Mosaic analysis with double markers in mice. Cell 121, 479-492.
-
(2005)
Cell
, vol.121
, pp. 479-492
-
-
Zong, H.1
Espinosa, J.S.2
Su, H.H.3
Muzumdar, M.D.4
Luo, L.5
|