CRISPR/Cas9 mediated knockout of rb1 and rbl1 leads to rapid and penetrant retinoblastoma development in Xenopus tropicalis

Scientific Reports

Volumn 6, Issue , 2016, Pages

  Naert, Thomas ^a   Colpaert, Robin ^a   Van Nieuwenhuysen, Tom ^a   Dimitrakopoulou, Dionysia ^a   Leoen, Jannick ^b   Haustraete, Jurgen ^b   Boel, Annekatrien ^c   Steyaert, Wouter ^c   Lepez, Trees ^a   Deforce, Dieter ^a   Willaert, Andy ^c   Creytens, David ^c   Vleminckx, Kris ^a,c  

^a GHENT UNIVERSITY   (Belgium)

^b DEPARTMENT OF PLANT SYSTEMS BIOLOGY   (Belgium)

^c GHENT UNIVERSITY HOSPITAL   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN P107; RETINOBLASTOMA BINDING PROTEIN; RETINOBLASTOMA PROTEIN;

ANIMAL; CLUSTERED REGULARLY INTERSPACED SHORT PALINDROMIC REPEAT; CRISPR CAS SYSTEM; DISEASE MODEL; EYE TUMOR; GENE KNOCKOUT; GENETICS; PATHOLOGY; PROCEDURES; RETINOBLASTOMA; XENOPUS;

ANIMALS; CLUSTERED REGULARLY INTERSPACED SHORT PALINDROMIC REPEATS; CRISPR-CAS SYSTEMS; DISEASE MODELS, ANIMAL; EYE NEOPLASMS; GENE KNOCKOUT TECHNIQUES; RETINOBLASTOMA; RETINOBLASTOMA BINDING PROTEINS; RETINOBLASTOMA PROTEIN; RETINOBLASTOMA-LIKE PROTEIN P107; XENOPUS;

EID: 84991730022     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep35264     Document Type: Article

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