-
1
-
-
0037054033
-
Relationship between physical activity and inflammation among apparently healthy middle-aged and older US adults
-
Abramson, J.L., Vaccarino, V., Relationship between physical activity and inflammation among apparently healthy middle-aged and older US adults. Arch. Intern. Med. 162 (2002), 1286–1292.
-
(2002)
Arch. Intern. Med.
, vol.162
, pp. 1286-1292
-
-
Abramson, J.L.1
Vaccarino, V.2
-
2
-
-
84918583229
-
Metformin directly acts on mitochondria to alter cellular bioenergetics
-
Andrzejewski, S., Gravel, S.P., Pollak, M., St-Pierre, J., Metformin directly acts on mitochondria to alter cellular bioenergetics. Cancer Metab., 2, 2014, 12.
-
(2014)
Cancer Metab.
, vol.2
, pp. 12
-
-
Andrzejewski, S.1
Gravel, S.P.2
Pollak, M.3
St-Pierre, J.4
-
3
-
-
0022448213
-
Muscle morphology, enzymatic activity, and muscle strength in elderly men: a follow-up study
-
Aniansson, A., Hedberg, M., Henning, G.B., Grimby, G., Muscle morphology, enzymatic activity, and muscle strength in elderly men: a follow-up study. Muscle Nerve 9 (1986), 585–591.
-
(1986)
Muscle Nerve
, vol.9
, pp. 585-591
-
-
Aniansson, A.1
Hedberg, M.2
Henning, G.B.3
Grimby, G.4
-
4
-
-
74549131244
-
Metformin extends life span of HER-2/neu transgenic mice and in combination with melatonin inhibits growth of transplantable tumors in vivo
-
Anisimov, V.N., Egormin, P.A., Piskunova, T.S., Popovich, I.G., Tyndyk, M.L., Yurova, M.N., Zabezhinski, M.A., Anikin, I.V., Karkach, A.S., Romanyukha, A.A., Metformin extends life span of HER-2/neu transgenic mice and in combination with melatonin inhibits growth of transplantable tumors in vivo. Cell Cycle 9 (2010), 188–197.
-
(2010)
Cell Cycle
, vol.9
, pp. 188-197
-
-
Anisimov, V.N.1
Egormin, P.A.2
Piskunova, T.S.3
Popovich, I.G.4
Tyndyk, M.L.5
Yurova, M.N.6
Zabezhinski, M.A.7
Anikin, I.V.8
Karkach, A.S.9
Romanyukha, A.A.10
-
5
-
-
77952878939
-
Subregional hippocampal atrophy predicts Alzheimer's dementia in the cognitively normal
-
Apostolova, L.G., Mosconi, L., Thompson, P.M., Green, A.E., Hwang, K.S., Ramirez, A., Mistur, R., Tsui, W.H., de Leon, M.J., Subregional hippocampal atrophy predicts Alzheimer's dementia in the cognitively normal. Neurobiol. Aging 31 (2010), 1077–1088.
-
(2010)
Neurobiol. Aging
, vol.31
, pp. 1077-1088
-
-
Apostolova, L.G.1
Mosconi, L.2
Thompson, P.M.3
Green, A.E.4
Hwang, K.S.5
Ramirez, A.6
Mistur, R.7
Tsui, W.H.8
de Leon, M.J.9
-
6
-
-
85001741005
-
Alternative rapamycin treatment regimens mitigate the impact of rapamycin on glucose homeostasis and the immune system
-
Arriola Apelo, S.I., Neuman, J.C., Baar, E.L., Syed, F.A., Cummings, N.E., Brar, H.K., Pumper, C.P., Kimple, M.E., Lamming, D.W., Alternative rapamycin treatment regimens mitigate the impact of rapamycin on glucose homeostasis and the immune system. Aging Cell, 2015.
-
(2015)
Aging Cell
-
-
Arriola Apelo, S.I.1
Neuman, J.C.2
Baar, E.L.3
Syed, F.A.4
Cummings, N.E.5
Brar, H.K.6
Pumper, C.P.7
Kimple, M.E.8
Lamming, D.W.9
-
7
-
-
0034663138
-
Effect of a preoperative intervention on preoperative and postoperative outcomes in low-risk patients awaiting elective coronary artery bypass graft surgery. A randomized, controlled trial
-
Arthur, H.M., Daniels, C., McKelvie, R., Hirsh, J., Rush, B., Effect of a preoperative intervention on preoperative and postoperative outcomes in low-risk patients awaiting elective coronary artery bypass graft surgery. A randomized, controlled trial. Ann. Intern. Med. 133 (2000), 253–262.
-
(2000)
Ann. Intern. Med.
, vol.133
, pp. 253-262
-
-
Arthur, H.M.1
Daniels, C.2
McKelvie, R.3
Hirsh, J.4
Rush, B.5
-
8
-
-
84866178861
-
Ageing: mixed results for dieting monkeys
-
Austad, S.N., Ageing: mixed results for dieting monkeys. Nature 489 (2012), 210–211.
-
(2012)
Nature
, vol.489
, pp. 210-211
-
-
Austad, S.N.1
-
9
-
-
33746655748
-
No decline in skeletal muscle oxidative capacity with aging in long-term calorically restricted rats: effects are independent of mitochondrial DNA integrity
-
Baker, D.J., Betik, A.C., Krause, D.J., Hepple, R.T., No decline in skeletal muscle oxidative capacity with aging in long-term calorically restricted rats: effects are independent of mitochondrial DNA integrity. J. Gerontol. A Biol. Sci. Med. Sci. 61 (2006), 675–684.
-
(2006)
J. Gerontol. A Biol. Sci. Med. Sci.
, vol.61
, pp. 675-684
-
-
Baker, D.J.1
Betik, A.C.2
Krause, D.J.3
Hepple, R.T.4
-
10
-
-
84914165449
-
Can people with type 2 diabetes live longer than those without? A comparison of mortality in people initiated with metformin or sulphonylurea monotherapy and matched, non-diabetic controls
-
Bannister, C.A., Holden, S.E., Jenkins-Jones, S., Morgan, C.L., Halcox, J.P., Schernthaner, G., Mukherjee, J., Currie, C.J., Can people with type 2 diabetes live longer than those without? A comparison of mortality in people initiated with metformin or sulphonylurea monotherapy and matched, non-diabetic controls. Diabetes Obes. Metab. 16 (2014), 1165–1173.
-
(2014)
Diabetes Obes. Metab.
, vol.16
, pp. 1165-1173
-
-
Bannister, C.A.1
Holden, S.E.2
Jenkins-Jones, S.3
Morgan, C.L.4
Halcox, J.P.5
Schernthaner, G.6
Mukherjee, J.7
Currie, C.J.8
-
11
-
-
48349110303
-
A low dose of dietary resveratrol partially mimics caloric restriction and retards aging parameters in mice
-
e2264
-
Barger, J.L., Kayo, T., Vann, J.M., Arias, E.B., Wang, J., Hacker, T.A., Wang, Y., Raederstorff, D., Morrow, J.D., Leeuwenburgh, C., Allison, D.B., Saupe, K.W., Cartee, G.D., Weindruch, R., Prolla, T.A., A low dose of dietary resveratrol partially mimics caloric restriction and retards aging parameters in mice. PLoS One, 3, 2008, e2264.
-
(2008)
PLoS One
, vol.3
-
-
Barger, J.L.1
Kayo, T.2
Vann, J.M.3
Arias, E.B.4
Wang, J.5
Hacker, T.A.6
Wang, Y.7
Raederstorff, D.8
Morrow, J.D.9
Leeuwenburgh, C.10
Allison, D.B.11
Saupe, K.W.12
Cartee, G.D.13
Weindruch, R.14
Prolla, T.A.15
-
12
-
-
84861885929
-
The critical role of metabolic pathways in aging
-
Barzilai, N., Huffman, D.M., Muzumdar, R.H., Bartke, A., The critical role of metabolic pathways in aging. Diabetes 61 (2012), 1315–1322.
-
(2012)
Diabetes
, vol.61
, pp. 1315-1322
-
-
Barzilai, N.1
Huffman, D.M.2
Muzumdar, R.H.3
Bartke, A.4
-
13
-
-
33751072349
-
Resveratrol improves health and survival of mice on a high-calorie diet
-
Baur, J.A., Pearson, K.J., Price, N.L., Jamieson, H.A., Lerin, C., Kalra, A., Prabhu, V.V., Allard, J.S., Lopez-Lluch, G., Lewis, K., Pistell, P.J., Poosala, S., Becker, K.G., Boss, O., Gwinn, D., Wang, M., Ramaswamy, S., Fishbein, K.W., Spencer, R.G., Lakatta, E.G., Le Couteur, D., Shaw, R.J., Navas, P., Puigserver, P., Ingram, D.K., de Cabo, R., Sinclair, D.A., Resveratrol improves health and survival of mice on a high-calorie diet. Nature 444 (2006), 337–342.
-
(2006)
Nature
, vol.444
, pp. 337-342
-
-
Baur, J.A.1
Pearson, K.J.2
Price, N.L.3
Jamieson, H.A.4
Lerin, C.5
Kalra, A.6
Prabhu, V.V.7
Allard, J.S.8
Lopez-Lluch, G.9
Lewis, K.10
Pistell, P.J.11
Poosala, S.12
Becker, K.G.13
Boss, O.14
Gwinn, D.15
Wang, M.16
Ramaswamy, S.17
Fishbein, K.W.18
Spencer, R.G.19
Lakatta, E.G.20
Le Couteur, D.21
Shaw, R.J.22
Navas, P.23
Puigserver, P.24
Ingram, D.K.25
de Cabo, R.26
Sinclair, D.A.27
more..
-
14
-
-
84892619153
-
Effects of resveratrol on the recovery of muscle mass following disuse in the plantaris muscle of aged rats
-
e83518
-
Bennett, B.T., Mohamed, J.S., Alway, S.E., Effects of resveratrol on the recovery of muscle mass following disuse in the plantaris muscle of aged rats. PLoS One, 8, 2013, e83518.
-
(2013)
PLoS One
, vol.8
-
-
Bennett, B.T.1
Mohamed, J.S.2
Alway, S.E.3
-
15
-
-
34548393607
-
Frailty: an emerging research and clinical paradigm–issues and controversies
-
Bergman, H., Ferrucci, L., Guralnik, J., Hogan, D.B., Hummel, S., Karunananthan, S., Wolfson, C., Frailty: an emerging research and clinical paradigm–issues and controversies. J. Gerontol. A Biol. Sci. Med. Sci. 62 (2007), 731–737.
-
(2007)
J. Gerontol. A Biol. Sci. Med. Sci.
, vol.62
, pp. 731-737
-
-
Bergman, H.1
Ferrucci, L.2
Guralnik, J.3
Hogan, D.B.4
Hummel, S.5
Karunananthan, S.6
Wolfson, C.7
-
16
-
-
84976406800
-
Resveratrol supplementation confers neuroprotection in cortical brain tissue of nonhuman primates fed a high-fat/sucrose diet
-
(epub ahead of print)
-
Bernier, M., Wahl, D., Ali, A., Allard, J., Faulkner, S., Wnorowski, A., Sanghvi, M., Moaddel, R., Alfaras, I., Mattison, J.A., Tarantini, S., Tucsek, Z., Ungvari, Z., Csiszar, A., Pearson, K.J., de Cabo, R., Resveratrol supplementation confers neuroprotection in cortical brain tissue of nonhuman primates fed a high-fat/sucrose diet. Aging (Albany NY), 2016 (epub ahead of print).
-
(2016)
Aging (Albany NY)
-
-
Bernier, M.1
Wahl, D.2
Ali, A.3
Allard, J.4
Faulkner, S.5
Wnorowski, A.6
Sanghvi, M.7
Moaddel, R.8
Alfaras, I.9
Mattison, J.A.10
Tarantini, S.11
Tucsek, Z.12
Ungvari, Z.13
Csiszar, A.14
Pearson, K.J.15
de Cabo, R.16
-
17
-
-
34547907489
-
Calorie restriction accelerates the catabolism of lean body mass during 2 wk of bed rest
-
Biolo, G., Ciocchi, B., Stulle, M., Bosutti, A., Barazzoni, R., Zanetti, M., Antonione, R., Lebenstedt, M., Platen, P., Heer, M., Guarnieri, G., Calorie restriction accelerates the catabolism of lean body mass during 2 wk of bed rest. Am. J. Clin. Nutr. 86 (2007), 366–372.
-
(2007)
Am. J. Clin. Nutr.
, vol.86
, pp. 366-372
-
-
Biolo, G.1
Ciocchi, B.2
Stulle, M.3
Bosutti, A.4
Barazzoni, R.5
Zanetti, M.6
Antonione, R.7
Lebenstedt, M.8
Platen, P.9
Heer, M.10
Guarnieri, G.11
-
18
-
-
84862234497
-
Lack of exercise is a major cause of chronic diseases
-
Booth, F.W., Roberts, C.K., Laye, M.J., Lack of exercise is a major cause of chronic diseases. Compr. Physiol. 2 (2012), 1143–1211.
-
(2012)
Compr. Physiol.
, vol.2
, pp. 1143-1211
-
-
Booth, F.W.1
Roberts, C.K.2
Laye, M.J.3
-
19
-
-
0035430177
-
Suppression of angiogenesis, tumor growth, and wound healing by resveratrol, a natural compound in red wine and grapes
-
Brakenhielm, E., Cao, R., Cao, Y., Suppression of angiogenesis, tumor growth, and wound healing by resveratrol, a natural compound in red wine and grapes. FASEB J. 15 (2001), 1798–1800.
-
(2001)
FASEB J.
, vol.15
, pp. 1798-1800
-
-
Brakenhielm, E.1
Cao, R.2
Cao, Y.3
-
20
-
-
84883455877
-
Short-term calorie and protein restriction provide partial protection from chemotoxicity but do not delay glioma progression
-
Brandhorst, S., Wei, M., Hwang, S., Morgan, T.E., Longo, V.D., Short-term calorie and protein restriction provide partial protection from chemotoxicity but do not delay glioma progression. Exp. Gerontol. 48 (2013), 1120–1128.
-
(2013)
Exp. Gerontol.
, vol.48
, pp. 1120-1128
-
-
Brandhorst, S.1
Wei, M.2
Hwang, S.3
Morgan, T.E.4
Longo, V.D.5
-
21
-
-
38349138918
-
The effects of sirolimus on wound healing in dermatologic surgery
-
Brewer, J.D., Otley, C.C., Christenson, L.J., Phillips, P.K., Roenigk, R.K., Weaver, A.L., The effects of sirolimus on wound healing in dermatologic surgery. Dermatol. Surg. 34 (2008), 216–223.
-
(2008)
Dermatol. Surg.
, vol.34
, pp. 216-223
-
-
Brewer, J.D.1
Otley, C.C.2
Christenson, L.J.3
Phillips, P.K.4
Roenigk, R.K.5
Weaver, A.L.6
-
22
-
-
50649116617
-
Resistance training and timed essential amino acids protect against the loss of muscle mass and strength during 28 days of bed rest and energy deficit
-
Brooks, N., Cloutier, G.J., Cadena, S.M., Layne, J.E., Nelsen, C.A., Freed, A.M., Roubenoff, R., Castaneda-Sceppa, C., Resistance training and timed essential amino acids protect against the loss of muscle mass and strength during 28 days of bed rest and energy deficit. J. Appl. Physiol. (1985) 105 (2008), 241–248.
-
(2008)
J. Appl. Physiol. (1985)
, vol.105
, pp. 241-248
-
-
Brooks, N.1
Cloutier, G.J.2
Cadena, S.M.3
Layne, J.E.4
Nelsen, C.A.5
Freed, A.M.6
Roubenoff, R.7
Castaneda-Sceppa, C.8
-
23
-
-
74549151265
-
The effects of resveratrol on the healing of left colonic anastomosis
-
Cakmak, G.K., Irkorucu, O., Ucan, B.H., Tascilar, O., Emre, A.U., Karakaya, K., Bahadir, B., Acikgoz, S., Pasaoglu, H., Ankarali, H., Ugurbas, E., Demirtas, C., Comert, M., The effects of resveratrol on the healing of left colonic anastomosis. J. Investig. Surg. 22 (2009), 353–361.
-
(2009)
J. Investig. Surg.
, vol.22
, pp. 353-361
-
-
Cakmak, G.K.1
Irkorucu, O.2
Ucan, B.H.3
Tascilar, O.4
Emre, A.U.5
Karakaya, K.6
Bahadir, B.7
Acikgoz, S.8
Pasaoglu, H.9
Ankarali, H.10
Ugurbas, E.11
Demirtas, C.12
Comert, M.13
-
24
-
-
79958792472
-
Exercise protects against myocardial ischemia-reperfusion injury via stimulation of beta(3)-adrenergic receptors and increased nitric oxide signaling: role of nitrite and nitrosothiols
-
Calvert, J.W., Condit, M.E., Aragon, J.P., Nicholson, C.K., Moody, B.F., Hood, R.L., Sindler, A.L., Gundewar, S., Seals, D.R., Barouch, L.A., Lefer, D.J., Exercise protects against myocardial ischemia-reperfusion injury via stimulation of beta(3)-adrenergic receptors and increased nitric oxide signaling: role of nitrite and nitrosothiols. Circ. Res. 108 (2011), 1448–1458.
-
(2011)
Circ. Res.
, vol.108
, pp. 1448-1458
-
-
Calvert, J.W.1
Condit, M.E.2
Aragon, J.P.3
Nicholson, C.K.4
Moody, B.F.5
Hood, R.L.6
Sindler, A.L.7
Gundewar, S.8
Seals, D.R.9
Barouch, L.A.10
Lefer, D.J.11
-
25
-
-
0023780536
-
Effect of chronic undernutrition on susceptibility to cold stress in young adult and aged rats
-
Campbell, B.A., Richardson, R., Effect of chronic undernutrition on susceptibility to cold stress in young adult and aged rats. Mech. Ageing Dev. 44 (1988), 193–202.
-
(1988)
Mech. Ageing Dev.
, vol.44
, pp. 193-202
-
-
Campbell, B.A.1
Richardson, R.2
-
26
-
-
84902156097
-
Resveratrol improves bone repair by modulation of bone morphogenetic proteins and osteopontin gene expression in rats
-
Casarin, R.C., Casati, M.Z., Pimentel, S.P., Cirano, F.R., Algayer, M., Pires, P.R., Ghiraldini, B., Duarte, P.M., Ribeiro, F.V., Resveratrol improves bone repair by modulation of bone morphogenetic proteins and osteopontin gene expression in rats. Int. J. Oral Maxillofac. Surg. 43 (2014), 900–906.
-
(2014)
Int. J. Oral Maxillofac. Surg.
, vol.43
, pp. 900-906
-
-
Casarin, R.C.1
Casati, M.Z.2
Pimentel, S.P.3
Cirano, F.R.4
Algayer, M.5
Pires, P.R.6
Ghiraldini, B.7
Duarte, P.M.8
Ribeiro, F.V.9
-
27
-
-
79961211386
-
Alternate-day fasting reverses the age-associated hypertrophy phenotype in rat heart by influencing the ERK and PI3K signaling pathways
-
Castello, L., Maina, M., Testa, G., Cavallini, G., Biasi, F., Donati, A., Leonarduzzi, G., Bergamini, E., Poli, G., Chiarpotto, E., Alternate-day fasting reverses the age-associated hypertrophy phenotype in rat heart by influencing the ERK and PI3K signaling pathways. Mech. Ageing Dev. 132 (2011), 305–314.
-
(2011)
Mech. Ageing Dev.
, vol.132
, pp. 305-314
-
-
Castello, L.1
Maina, M.2
Testa, G.3
Cavallini, G.4
Biasi, F.5
Donati, A.6
Leonarduzzi, G.7
Bergamini, E.8
Poli, G.9
Chiarpotto, E.10
-
28
-
-
84881089080
-
Will calorie restriction work in humans?
-
Cava, E., Fontana, L., Will calorie restriction work in humans?. Aging (Albany NY) 5 (2013), 507–514.
-
(2013)
Aging (Albany NY)
, vol.5
, pp. 507-514
-
-
Cava, E.1
Fontana, L.2
-
29
-
-
84954218515
-
Clearance of senescent cells by ABT263 rejuvenates aged hematopoietic stem cells in mice
-
Chang, J., Wang, Y., Shao, L., Laberge, R.M., Demaria, M., Campisi, J., Janakiraman, K., Sharpless, N.E., Ding, S., Feng, W., Luo, Y., Wang, X., Aykin-Burns, N., Krager, K., Ponnappan, U., Hauer-Jensen, M., Meng, A., Zhou, D., Clearance of senescent cells by ABT263 rejuvenates aged hematopoietic stem cells in mice. Nat. Med. 22 (2016), 78–83.
-
(2016)
Nat. Med.
, vol.22
, pp. 78-83
-
-
Chang, J.1
Wang, Y.2
Shao, L.3
Laberge, R.M.4
Demaria, M.5
Campisi, J.6
Janakiraman, K.7
Sharpless, N.E.8
Ding, S.9
Feng, W.10
Luo, Y.11
Wang, X.12
Aykin-Burns, N.13
Krager, K.14
Ponnappan, U.15
Hauer-Jensen, M.16
Meng, A.17
Zhou, D.18
-
30
-
-
85044691446
-
Anti-ageing pill pushed as bona fide drug
-
Check Hayden, E., Anti-ageing pill pushed as bona fide drug. Nature 522 (2015), 265–266.
-
(2015)
Nature
, vol.522
, pp. 265-266
-
-
Check Hayden, E.1
-
31
-
-
77955300350
-
Short-term re-feeding of previously energy-restricted C57BL/6 male mice restores body weight and body fat and attenuates the decline in natural killer cell function after primary influenza infection
-
Clinthorne, J.F., Adams, D.J., Fenton, J.I., Ritz, B.W., Gardner, E.M., Short-term re-feeding of previously energy-restricted C57BL/6 male mice restores body weight and body fat and attenuates the decline in natural killer cell function after primary influenza infection. J. Nutr. 140 (2010), 1495–1501.
-
(2010)
J. Nutr.
, vol.140
, pp. 1495-1501
-
-
Clinthorne, J.F.1
Adams, D.J.2
Fenton, J.I.3
Ritz, B.W.4
Gardner, E.M.5
-
32
-
-
84872189584
-
NK cell maturation and function in C57BL/6 mice are altered by caloric restriction
-
Clinthorne, J.F., Beli, E., Duriancik, D.M., Gardner, E.M., NK cell maturation and function in C57BL/6 mice are altered by caloric restriction. J. Immunol. 190 (2013), 712–722.
-
(2013)
J. Immunol.
, vol.190
, pp. 712-722
-
-
Clinthorne, J.F.1
Beli, E.2
Duriancik, D.M.3
Gardner, E.M.4
-
33
-
-
33845943769
-
Aerobic exercise training increases brain volume in aging humans
-
Colcombe, S.J., Erickson, K.I., Scalf, P.E., Kim, J.S., Prakash, R., McAuley, E., Elavsky, S., Marquez, D.X., Hu, L., Kramer, A.F., Aerobic exercise training increases brain volume in aging humans. J. Gerontol. A Biol. Sci. Med. Sci. 61 (2006), 1166–1170.
-
(2006)
J. Gerontol. A Biol. Sci. Med. Sci.
, vol.61
, pp. 1166-1170
-
-
Colcombe, S.J.1
Erickson, K.I.2
Scalf, P.E.3
Kim, J.S.4
Prakash, R.5
McAuley, E.6
Elavsky, S.7
Marquez, D.X.8
Hu, L.9
Kramer, A.F.10
-
34
-
-
84891713034
-
Senescence-associated secretory phenotypes reveal cell-nonautonomous functions of oncogenic RAS and the p53 tumor suppressor
-
Coppe, J.P., Patil, C.K., Rodier, F., Sun, Y., Munoz, D.P., Goldstein, J., Nelson, P.S., Desprez, P.Y., Campisi, J., Senescence-associated secretory phenotypes reveal cell-nonautonomous functions of oncogenic RAS and the p53 tumor suppressor. PLoS Biol. 6 (2008), 2853–2868.
-
(2008)
PLoS Biol.
, vol.6
, pp. 2853-2868
-
-
Coppe, J.P.1
Patil, C.K.2
Rodier, F.3
Sun, Y.4
Munoz, D.P.5
Goldstein, J.6
Nelson, P.S.7
Desprez, P.Y.8
Campisi, J.9
-
35
-
-
77949458344
-
A human-like senescence-associated secretory phenotype is conserved in mouse cells dependent on physiological oxygen
-
e9188
-
Coppe, J.P., Patil, C.K., Rodier, F., Krtolica, A., Beausejour, C.M., Parrinello, S., Hodgson, J.G., Chin, K., Desprez, P.Y., Campisi, J., A human-like senescence-associated secretory phenotype is conserved in mouse cells dependent on physiological oxygen. PLoS One, 5, 2010, e9188.
-
(2010)
PLoS One
, vol.5
-
-
Coppe, J.P.1
Patil, C.K.2
Rodier, F.3
Krtolica, A.4
Beausejour, C.M.5
Parrinello, S.6
Hodgson, J.G.7
Chin, K.8
Desprez, P.Y.9
Campisi, J.10
-
36
-
-
4043154106
-
Changes in satellite cells in human skeletal muscle after a single bout of high intensity exercise
-
Crameri, R.M., Langberg, H., Magnusson, P., Jensen, C.H., Schroder, H.D., Olesen, J.L., Suetta, C., Teisner, B., Kjaer, M., Changes in satellite cells in human skeletal muscle after a single bout of high intensity exercise. J. Physiol. 558 (2004), 333–340.
-
(2004)
J. Physiol.
, vol.558
, pp. 333-340
-
-
Crameri, R.M.1
Langberg, H.2
Magnusson, P.3
Jensen, C.H.4
Schroder, H.D.5
Olesen, J.L.6
Suetta, C.7
Teisner, B.8
Kjaer, M.9
-
37
-
-
84860131782
-
Pilot study of resveratrol in older adults with impaired glucose tolerance
-
Crandall, J.P., Oram, V., Trandafirescu, G., Reid, M., Kishore, P., Hawkins, M., Cohen, H.W., Barzilai, N., Pilot study of resveratrol in older adults with impaired glucose tolerance. J. Gerontol. A Biol. Sci. Med. Sci. 67 (2012), 1307–1312.
-
(2012)
J. Gerontol. A Biol. Sci. Med. Sci.
, vol.67
, pp. 1307-1312
-
-
Crandall, J.P.1
Oram, V.2
Trandafirescu, G.3
Reid, M.4
Kishore, P.5
Hawkins, M.6
Cohen, H.W.7
Barzilai, N.8
-
38
-
-
67349234999
-
Resveratrol prevents doxorubicin cardiotoxicity through mitochondrial stabilization and the Sirt1 pathway
-
Danz, E.D., Skramsted, J., Henry, N., Bennett, J.A., Keller, R.S., Resveratrol prevents doxorubicin cardiotoxicity through mitochondrial stabilization and the Sirt1 pathway. Free Radic. Biol. Med. 46 (2009), 1589–1597.
-
(2009)
Free Radic. Biol. Med.
, vol.46
, pp. 1589-1597
-
-
Danz, E.D.1
Skramsted, J.2
Henry, N.3
Bennett, J.A.4
Keller, R.S.5
-
39
-
-
0020383969
-
Free radicals and tissue damage produced by exercise
-
Davies, K.J., Quintanilha, A.T., Brooks, G.A., Packer, L., Free radicals and tissue damage produced by exercise. Biochem. Biophys. Res. Commun. 107 (1982), 1198–1205.
-
(1982)
Biochem. Biophys. Res. Commun.
, vol.107
, pp. 1198-1205
-
-
Davies, K.J.1
Quintanilha, A.T.2
Brooks, G.A.3
Packer, L.4
-
40
-
-
0942265634
-
Effects of moderate exercise and oat beta-glucan on innate immune function and susceptibility to respiratory infection
-
Davis, J.M., Murphy, E.A., Brown, A.S., Carmichael, M.D., Ghaffar, A., Mayer, E.P., Effects of moderate exercise and oat beta-glucan on innate immune function and susceptibility to respiratory infection. Am. J. Phys. Regul. Integr. Comp. Phys. 286 (2004), R366–R372.
-
(2004)
Am. J. Phys. Regul. Integr. Comp. Phys.
, vol.286
, pp. R366-R372
-
-
Davis, J.M.1
Murphy, E.A.2
Brown, A.S.3
Carmichael, M.D.4
Ghaffar, A.5
Mayer, E.P.6
-
41
-
-
84859623280
-
Regular and moderate exercise before experimental sepsis reduces the risk of lung and distal organ injury
-
de Araujo, C.C., Silva, J.D., Samary, C.S., Guimaraes, I.H., Marques, P.S., Oliveira, G.P., do Carmo, L.G., Goldenberg, R.C., Bakker-Abreu, I., Diaz, B.L., Rocha, N.N., Capelozzi, V.L., Pelosi, P., Rocco, P.R., Regular and moderate exercise before experimental sepsis reduces the risk of lung and distal organ injury. J. Appl. Physiol. (1985) 112 (2012), 1206–1214.
-
(2012)
J. Appl. Physiol. (1985)
, vol.112
, pp. 1206-1214
-
-
de Araujo, C.C.1
Silva, J.D.2
Samary, C.S.3
Guimaraes, I.H.4
Marques, P.S.5
Oliveira, G.P.6
do Carmo, L.G.7
Goldenberg, R.C.8
Bakker-Abreu, I.9
Diaz, B.L.10
Rocha, N.N.11
Capelozzi, V.L.12
Pelosi, P.13
Rocco, P.R.14
-
42
-
-
84975693015
-
Telomere length maintenance and cardio-metabolic disease prevention through exercise training
-
Denham, J., O'Brien, B.J., Charchar, F.J., Telomere length maintenance and cardio-metabolic disease prevention through exercise training. Sports Med., 2016.
-
(2016)
Sports Med.
-
-
Denham, J.1
O'Brien, B.J.2
Charchar, F.J.3
-
43
-
-
77955845727
-
Caloric restriction leads to high marrow adiposity and low bone mass in growing mice
-
Devlin, M.J., Cloutier, A.M., Thomas, N.A., Panus, D.A., Lotinun, S., Pinz, I., Baron, R., Rosen, C.J., Bouxsein, M.L., Caloric restriction leads to high marrow adiposity and low bone mass in growing mice. J. Bone Miner. Res. 25 (2010), 2078–2088.
-
(2010)
J. Bone Miner. Res.
, vol.25
, pp. 2078-2088
-
-
Devlin, M.J.1
Cloutier, A.M.2
Thomas, N.A.3
Panus, D.A.4
Lotinun, S.5
Pinz, I.6
Baron, R.7
Rosen, C.J.8
Bouxsein, M.L.9
-
44
-
-
33847628737
-
Recent metformin ingestion does not increase in-hospital morbidity or mortality after cardiac surgery
-
Duncan, A.I., Koch, C.G., Xu, M., Manlapaz, M., Batdorf, B., Pitas, G., Starr, N., Recent metformin ingestion does not increase in-hospital morbidity or mortality after cardiac surgery. Anesth. Analg. 104 (2007), 42–50.
-
(2007)
Anesth. Analg.
, vol.104
, pp. 42-50
-
-
Duncan, A.I.1
Koch, C.G.2
Xu, M.3
Manlapaz, M.4
Batdorf, B.5
Pitas, G.6
Starr, N.7
-
45
-
-
84905389709
-
Calorie restriction combined with resveratrol induces autophagy and protects 26-month-old rat hearts from doxorubicin-induced toxicity
-
Dutta, D., Xu, J., Dirain, M.L., Leeuwenburgh, C., Calorie restriction combined with resveratrol induces autophagy and protects 26-month-old rat hearts from doxorubicin-induced toxicity. Free Radic. Biol. Med. 74 (2014), 252–262.
-
(2014)
Free Radic. Biol. Med.
, vol.74
, pp. 252-262
-
-
Dutta, D.1
Xu, J.2
Dirain, M.L.3
Leeuwenburgh, C.4
-
46
-
-
81255157471
-
Interleukin-6 enhances insulin secretion by increasing glucagon-like peptide-1 secretion from L cells and alpha cells
-
Ellingsgaard, H., Hauselmann, I., Schuler, B., Habib, A.M., Baggio, L.L., Meier, D.T., Eppler, E., Bouzakri, K., Wueest, S., Muller, Y.D., Hansen, A.M., Reinecke, M., Konrad, D., Gassmann, M., Reimann, F., Halban, P.A., Gromada, J., Drucker, D.J., Gribble, F.M., Ehses, J.A., Donath, M.Y., Interleukin-6 enhances insulin secretion by increasing glucagon-like peptide-1 secretion from L cells and alpha cells. Nat. Med. 17 (2011), 1481–1489.
-
(2011)
Nat. Med.
, vol.17
, pp. 1481-1489
-
-
Ellingsgaard, H.1
Hauselmann, I.2
Schuler, B.3
Habib, A.M.4
Baggio, L.L.5
Meier, D.T.6
Eppler, E.7
Bouzakri, K.8
Wueest, S.9
Muller, Y.D.10
Hansen, A.M.11
Reinecke, M.12
Konrad, D.13
Gassmann, M.14
Reimann, F.15
Halban, P.A.16
Gromada, J.17
Drucker, D.J.18
Gribble, F.M.19
Ehses, J.A.20
Donath, M.Y.21
more..
-
47
-
-
79952611543
-
Exercise training increases size of hippocampus and improves memory
-
Erickson, K.I., Voss, M.W., Prakash, R.S., Basak, C., Szabo, A., Chaddock, L., Kim, J.S., Heo, S., Alves, H., White, S.M., Wojcicki, T.R., Mailey, E., Vieira, V.J., Martin, S.A., Pence, B.D., Woods, J.A., McAuley, E., Kramer, A.F., Exercise training increases size of hippocampus and improves memory. Proc. Natl. Acad. Sci. U. S. A. 108 (2011), 3017–3022.
-
(2011)
Proc. Natl. Acad. Sci. U. S. A.
, vol.108
, pp. 3017-3022
-
-
Erickson, K.I.1
Voss, M.W.2
Prakash, R.S.3
Basak, C.4
Szabo, A.5
Chaddock, L.6
Kim, J.S.7
Heo, S.8
Alves, H.9
White, S.M.10
Wojcicki, T.R.11
Mailey, E.12
Vieira, V.J.13
Martin, S.A.14
Pence, B.D.15
Woods, J.A.16
McAuley, E.17
Kramer, A.F.18
-
48
-
-
77950485782
-
Skeletal muscle loss: cachexia, sarcopenia, and inactivity
-
Evans, W.J., Skeletal muscle loss: cachexia, sarcopenia, and inactivity. Am. J. Clin. Nutr. 91 (2010), 1123S–1127S.
-
(2010)
Am. J. Clin. Nutr.
, vol.91
, pp. 1123S-1127S
-
-
Evans, W.J.1
-
49
-
-
84922470859
-
Aging and the burden of multimorbidity: associations with inflammatory and anabolic hormonal biomarkers
-
Fabbri, E., An, Y., Zoli, M., Simonsick, E.M., Guralnik, J.M., Bandinelli, S., Boyd, C.M., Ferrucci, L., Aging and the burden of multimorbidity: associations with inflammatory and anabolic hormonal biomarkers. J. Gerontol. A Biol. Sci. Med. Sci. 70 (2015), 63–70.
-
(2015)
J. Gerontol. A Biol. Sci. Med. Sci.
, vol.70
, pp. 63-70
-
-
Fabbri, E.1
An, Y.2
Zoli, M.3
Simonsick, E.M.4
Guralnik, J.M.5
Bandinelli, S.6
Boyd, C.M.7
Ferrucci, L.8
-
50
-
-
84875331396
-
Duration of rapamycin treatment has differential effects on metabolism in mice
-
Fang, Y., Westbrook, R., Hill, C., Boparai, R.K., Arum, O., Spong, A., Wang, F., Javors, M.A., Chen, J., Sun, L.Y., Bartke, A., Duration of rapamycin treatment has differential effects on metabolism in mice. Cell Metab. 17 (2013), 456–462.
-
(2013)
Cell Metab.
, vol.17
, pp. 456-462
-
-
Fang, Y.1
Westbrook, R.2
Hill, C.3
Boparai, R.K.4
Arum, O.5
Spong, A.6
Wang, F.7
Javors, M.A.8
Chen, J.9
Sun, L.Y.10
Bartke, A.11
-
51
-
-
56949104439
-
Mapping the road to resilience: novel math for the study of frailty
-
Ferrucci, L., Giallauria, F., Schlessinger, D., Mapping the road to resilience: novel math for the study of frailty. Mech. Ageing Dev. 129 (2008), 677–679.
-
(2008)
Mech. Ageing Dev.
, vol.129
, pp. 677-679
-
-
Ferrucci, L.1
Giallauria, F.2
Schlessinger, D.3
-
52
-
-
0028341292
-
Exercise training and nutritional supplementation for physical frailty in very elderly people
-
Fiatarone, M.A., O'Neill, E.F., Ryan, N.D., Clements, K.M., Solares, G.R., Nelson, M.E., Roberts, S.B., Kehayias, J.J., Lipsitz, L.A., Evans, W.J., Exercise training and nutritional supplementation for physical frailty in very elderly people. N. Engl. J. Med. 330 (1994), 1769–1775.
-
(1994)
N. Engl. J. Med.
, vol.330
, pp. 1769-1775
-
-
Fiatarone, M.A.1
O'Neill, E.F.2
Ryan, N.D.3
Clements, K.M.4
Solares, G.R.5
Nelson, M.E.6
Roberts, S.B.7
Kehayias, J.J.8
Lipsitz, L.A.9
Evans, W.J.10
-
53
-
-
84885132460
-
Resveratrol prevents beta-cell dedifferentiation in nonhuman primates given a high-fat/high-sugar diet
-
Fiori, J.L., Shin, Y.K., Kim, W., Krzysik-Walker, S.M., Gonzalez-Mariscal, I., Carlson, O.D., Sanghvi, M., Moaddel, R., Farhang, K., Gadkaree, S.K., Doyle, M.E., Pearson, K.J., Mattison, J.A., de Cabo, R., Egan, J.M., Resveratrol prevents beta-cell dedifferentiation in nonhuman primates given a high-fat/high-sugar diet. Diabetes 62 (2013), 3500–3513.
-
(2013)
Diabetes
, vol.62
, pp. 3500-3513
-
-
Fiori, J.L.1
Shin, Y.K.2
Kim, W.3
Krzysik-Walker, S.M.4
Gonzalez-Mariscal, I.5
Carlson, O.D.6
Sanghvi, M.7
Moaddel, R.8
Farhang, K.9
Gadkaree, S.K.10
Doyle, M.E.11
Pearson, K.J.12
Mattison, J.A.13
de Cabo, R.14
Egan, J.M.15
-
54
-
-
33746012931
-
Functional, structural and molecular plasticity of mammalian skeletal muscle in response to exercise stimuli
-
Fluck, M., Functional, structural and molecular plasticity of mammalian skeletal muscle in response to exercise stimuli. J. Exp. Biol. 209 (2006), 2239–2248.
-
(2006)
J. Exp. Biol.
, vol.209
, pp. 2239-2248
-
-
Fluck, M.1
-
55
-
-
2342647592
-
Long-term calorie restriction is highly effective in reducing the risk for atherosclerosis in humans
-
Fontana, L., Meyer, T.E., Klein, S., Holloszy, J.O., Long-term calorie restriction is highly effective in reducing the risk for atherosclerosis in humans. Proc. Natl. Acad. Sci. U. S. A. 101 (2004), 6659–6663.
-
(2004)
Proc. Natl. Acad. Sci. U. S. A.
, vol.101
, pp. 6659-6663
-
-
Fontana, L.1
Meyer, T.E.2
Klein, S.3
Holloszy, J.O.4
-
56
-
-
34250661042
-
Long-term low-calorie low-protein vegan diet and endurance exercise are associated with low cardiometabolic risk
-
Fontana, L., Meyer, T.E., Klein, S., Holloszy, J.O., Long-term low-calorie low-protein vegan diet and endurance exercise are associated with low cardiometabolic risk. Rejuvenation Res. 10 (2007), 225–234.
-
(2007)
Rejuvenation Res.
, vol.10
, pp. 225-234
-
-
Fontana, L.1
Meyer, T.E.2
Klein, S.3
Holloszy, J.O.4
-
57
-
-
77949424755
-
Effects of long-term calorie restriction and endurance exercise on glucose tolerance, insulin action, and adipokine production
-
Fontana, L., Klein, S., Holloszy, J.O., Effects of long-term calorie restriction and endurance exercise on glucose tolerance, insulin action, and adipokine production. Age (Dordr.) 32 (2010), 97–108.
-
(2010)
Age (Dordr.)
, vol.32
, pp. 97-108
-
-
Fontana, L.1
Klein, S.2
Holloszy, J.O.3
-
58
-
-
84919615360
-
Metformin: from mechanisms of action to therapies
-
Foretz, M., Guigas, B., Bertrand, L., Pollak, M., Viollet, B., Metformin: from mechanisms of action to therapies. Cell Metab. 20 (2014), 953–966.
-
(2014)
Cell Metab.
, vol.20
, pp. 953-966
-
-
Foretz, M.1
Guigas, B.2
Bertrand, L.3
Pollak, M.4
Viollet, B.5
-
59
-
-
84937768865
-
Metformin beyond diabetes: pleiotropic benefits of metformin in attenuation of atherosclerosis
-
e001202
-
Forouzandeh, F., Salazar, G., Patrushev, N., Xiong, S., Hilenski, L., Fei, B., Alexander, R.W., Metformin beyond diabetes: pleiotropic benefits of metformin in attenuation of atherosclerosis. J. Am. Heart Assoc., 3, 2014, e001202.
-
(2014)
J. Am. Heart Assoc.
, vol.3
-
-
Forouzandeh, F.1
Salazar, G.2
Patrushev, N.3
Xiong, S.4
Hilenski, L.5
Fei, B.6
Alexander, R.W.7
-
60
-
-
2442699834
-
Frailty in older adults: evidence for a phenotype
-
Fried, L.P., Tangen, C.M., Walston, J., Newman, A.B., Hirsch, C., Gottdiener, J., Seeman, T., Tracy, R., Kop, W.J., Burke, G., McBurnie, M.A., Frailty in older adults: evidence for a phenotype. J. Gerontol. A Biol. Sci. Med. Sci. 56 (2001), M146–M156.
-
(2001)
J. Gerontol. A Biol. Sci. Med. Sci.
, vol.56
, pp. M146-M156
-
-
Fried, L.P.1
Tangen, C.M.2
Walston, J.3
Newman, A.B.4
Hirsch, C.5
Gottdiener, J.6
Seeman, T.7
Tracy, R.8
Kop, W.J.9
Burke, G.10
McBurnie, M.A.11
-
61
-
-
84903852206
-
Life-long spontaneous exercise does not prolong lifespan but improves health span in mice
-
Garcia-Valles, R., Gomez-Cabrera, M.C., Rodriguez-Manas, L., Garcia-Garcia, F.J., Diaz, A., Noguera, I., Olaso-Gonzalez, G., Vina, J., Life-long spontaneous exercise does not prolong lifespan but improves health span in mice. Longev. Healthspan, 2, 2013, 14.
-
(2013)
Longev. Healthspan
, vol.2
, pp. 14
-
-
Garcia-Valles, R.1
Gomez-Cabrera, M.C.2
Rodriguez-Manas, L.3
Garcia-Garcia, F.J.4
Diaz, A.5
Noguera, I.6
Olaso-Gonzalez, G.7
Vina, J.8
-
62
-
-
21144439490
-
Caloric restriction decreases survival of aged mice in response to primary influenza infection
-
Gardner, E.M., Caloric restriction decreases survival of aged mice in response to primary influenza infection. J. Gerontol. A Biol. Sci. Med. Sci. 60 (2005), 688–694.
-
(2005)
J. Gerontol. A Biol. Sci. Med. Sci.
, vol.60
, pp. 688-694
-
-
Gardner, E.M.1
-
63
-
-
79960513808
-
Energy intake and response to infection with influenza
-
Gardner, E.M., Beli, E., Clinthorne, J.F., Duriancik, D.M., Energy intake and response to infection with influenza. Annu. Rev. Nutr. 31 (2011), 353–367.
-
(2011)
Annu. Rev. Nutr.
, vol.31
, pp. 353-367
-
-
Gardner, E.M.1
Beli, E.2
Clinthorne, J.F.3
Duriancik, D.M.4
-
64
-
-
84894412290
-
Metformin lowers plasma triglycerides by promoting VLDL-triglyceride clearance by brown adipose tissue in mice
-
Geerling, J.J., Boon, M.R., van der Zon, G.C., van den Berg, S.A., van den Hoek, A.M., Lombes, M., Princen, H.M., Havekes, L.M., Rensen, P.C., Guigas, B., Metformin lowers plasma triglycerides by promoting VLDL-triglyceride clearance by brown adipose tissue in mice. Diabetes 63 (2014), 880–891.
-
(2014)
Diabetes
, vol.63
, pp. 880-891
-
-
Geerling, J.J.1
Boon, M.R.2
van der Zon, G.C.3
van den Berg, S.A.4
van den Hoek, A.M.5
Lombes, M.6
Princen, H.M.7
Havekes, L.M.8
Rensen, P.C.9
Guigas, B.10
-
65
-
-
84914164117
-
Prehabilitation versus rehabilitation: a randomized control trial in patients undergoing colorectal resection for cancer
-
Gillis, C., Li, C., Lee, L., Awasthi, R., Augustin, B., Gamsa, A., Liberman, A.S., Stein, B., Charlebois, P., Feldman, L.S., Carli, F., Prehabilitation versus rehabilitation: a randomized control trial in patients undergoing colorectal resection for cancer. Anesthesiology 121 (2014), 937–947.
-
(2014)
Anesthesiology
, vol.121
, pp. 937-947
-
-
Gillis, C.1
Li, C.2
Lee, L.3
Awasthi, R.4
Augustin, B.5
Gamsa, A.6
Liberman, A.S.7
Stein, B.8
Charlebois, P.9
Feldman, L.S.10
Carli, F.11
-
66
-
-
84922636348
-
Lifespan-extending caloric restriction or mTOR inhibition impair adaptive immunity of old mice by distinct mechanisms
-
Goldberg, E.L., Romero-Aleshire, M.J., Renkema, K.R., Ventevogel, M.S., Chew, W.M., Uhrlaub, J.L., Smithey, M.J., Limesand, K.H., Sempowski, G.D., Brooks, H.L., Nikolich-Zugich, J., Lifespan-extending caloric restriction or mTOR inhibition impair adaptive immunity of old mice by distinct mechanisms. Aging Cell 14 (2015), 130–138.
-
(2015)
Aging Cell
, vol.14
, pp. 130-138
-
-
Goldberg, E.L.1
Romero-Aleshire, M.J.2
Renkema, K.R.3
Ventevogel, M.S.4
Chew, W.M.5
Uhrlaub, J.L.6
Smithey, M.J.7
Limesand, K.H.8
Sempowski, G.D.9
Brooks, H.L.10
Nikolich-Zugich, J.11
-
67
-
-
79951670197
-
Effect of prior treatment with resveratrol on density and structure of rat long bones under tail-suspension
-
Habold, C., Momken, I., Ouadi, A., Bekaert, V., Brasse, D., Effect of prior treatment with resveratrol on density and structure of rat long bones under tail-suspension. J. Bone Miner. Metab. 29 (2011), 15–22.
-
(2011)
J. Bone Miner. Metab.
, vol.29
, pp. 15-22
-
-
Habold, C.1
Momken, I.2
Ouadi, A.3
Bekaert, V.4
Brasse, D.5
-
68
-
-
33947264635
-
Intermittent fasting and caloric restriction ameliorate age-related behavioral deficits in the triple-transgenic mouse model of Alzheimer's disease
-
Halagappa, V.K., Guo, Z., Pearson, M., Matsuoka, Y., Cutler, R.G., Laferla, F.M., Mattson, M.P., Intermittent fasting and caloric restriction ameliorate age-related behavioral deficits in the triple-transgenic mouse model of Alzheimer's disease. Neurobiol. Dis. 26 (2007), 212–220.
-
(2007)
Neurobiol. Dis.
, vol.26
, pp. 212-220
-
-
Halagappa, V.K.1
Guo, Z.2
Pearson, M.3
Matsuoka, Y.4
Cutler, R.G.5
Laferla, F.M.6
Mattson, M.P.7
-
69
-
-
84865525400
-
Chronic inhibition of mammalian target of rapamycin by rapamycin modulates cognitive and non-cognitive components of behavior throughout lifespan in mice
-
Halloran, J., Hussong, S.A., Burbank, R., Podlutskaya, N., Fischer, K.E., Sloane, L.B., Austad, S.N., Strong, R., Richardson, A., Hart, M.J., Galvan, V., Chronic inhibition of mammalian target of rapamycin by rapamycin modulates cognitive and non-cognitive components of behavior throughout lifespan in mice. Neuroscience 223 (2012), 102–113.
-
(2012)
Neuroscience
, vol.223
, pp. 102-113
-
-
Halloran, J.1
Hussong, S.A.2
Burbank, R.3
Podlutskaya, N.4
Fischer, K.E.5
Sloane, L.B.6
Austad, S.N.7
Strong, R.8
Richardson, A.9
Hart, M.J.10
Galvan, V.11
-
70
-
-
84895825386
-
Acarbose, 17-alpha-estradiol, and nordihydroguaiaretic acid extend mouse lifespan preferentially in males
-
Harrison, D.E., Strong, R., Allison, D.B., Ames, B.N., Astle, C.M., Atamna, H., Fernandez, E., Flurkey, K., Javors, M.A., Nadon, N.L., Nelson, J.F., Pletcher, S., Simpkins, J.W., Smith, D., Wilkinson, J.E., Miller, R.A., Acarbose, 17-alpha-estradiol, and nordihydroguaiaretic acid extend mouse lifespan preferentially in males. Aging Cell 13 (2014), 273–282.
-
(2014)
Aging Cell
, vol.13
, pp. 273-282
-
-
Harrison, D.E.1
Strong, R.2
Allison, D.B.3
Ames, B.N.4
Astle, C.M.5
Atamna, H.6
Fernandez, E.7
Flurkey, K.8
Javors, M.A.9
Nadon, N.L.10
Nelson, J.F.11
Pletcher, S.12
Simpkins, J.W.13
Smith, D.14
Wilkinson, J.E.15
Miller, R.A.16
-
71
-
-
77951165669
-
Sirt1 activation protects the mouse renal medulla from oxidative injury
-
He, W., Wang, Y., Zhang, M.Z., You, L., Davis, L.S., Fan, H., Yang, H.C., Fogo, A.B., Zent, R., Harris, R.C., Breyer, M.D., Hao, C.M., Sirt1 activation protects the mouse renal medulla from oxidative injury. J. Clin. Invest. 120 (2010), 1056–1068.
-
(2010)
J. Clin. Invest.
, vol.120
, pp. 1056-1068
-
-
He, W.1
Wang, Y.2
Zhang, M.Z.3
You, L.4
Davis, L.S.5
Fan, H.6
Yang, H.C.7
Fogo, A.B.8
Zent, R.9
Harris, R.C.10
Breyer, M.D.11
Hao, C.M.12
-
72
-
-
84863393597
-
Exercise-induced BCL2-regulated autophagy is required for muscle glucose homeostasis
-
He, C., Bassik, M.C., Moresi, V., Sun, K., Wei, Y., Zou, Z., An, Z., Loh, J., Fisher, J., Sun, Q., Korsmeyer, S., Packer, M., May, H.I., Hill, J.A., Virgin, H.W., Gilpin, C., Xiao, G., Bassel-Duby, R., Scherer, P.E., Levine, B., Exercise-induced BCL2-regulated autophagy is required for muscle glucose homeostasis. Nature 481 (2012), 511–515.
-
(2012)
Nature
, vol.481
, pp. 511-515
-
-
He, C.1
Bassik, M.C.2
Moresi, V.3
Sun, K.4
Wei, Y.5
Zou, Z.6
An, Z.7
Loh, J.8
Fisher, J.9
Sun, Q.10
Korsmeyer, S.11
Packer, M.12
May, H.I.13
Hill, J.A.14
Virgin, H.W.15
Gilpin, C.16
Xiao, G.17
Bassel-Duby, R.18
Scherer, P.E.19
Levine, B.20
more..
-
73
-
-
84867249241
-
Exercise induces autophagy in peripheral tissues and in the brain
-
He, C., Sumpter, R. Jr., Levine, B., Exercise induces autophagy in peripheral tissues and in the brain. Autophagy 8 (2012), 1548–1551.
-
(2012)
Autophagy
, vol.8
, pp. 1548-1551
-
-
He, C.1
Sumpter, R.2
Levine, B.3
-
74
-
-
13744262254
-
Alternate-day fasting in nonobese subjects: effects on body weight, body composition, and energy metabolism
-
Heilbronn, L.K., Smith, S.R., Martin, C.K., Anton, S.D., Ravussin, E., Alternate-day fasting in nonobese subjects: effects on body weight, body composition, and energy metabolism. Am. J. Clin. Nutr. 81 (2005), 69–73.
-
(2005)
Am. J. Clin. Nutr.
, vol.81
, pp. 69-73
-
-
Heilbronn, L.K.1
Smith, S.R.2
Martin, C.K.3
Anton, S.D.4
Ravussin, E.5
-
75
-
-
33748323383
-
Regulation of cardiac hypertrophy by intracellular signalling pathways
-
Heineke, J., Molkentin, J.D., Regulation of cardiac hypertrophy by intracellular signalling pathways. Nat. Rev. Mol. Cell Biol. 7 (2006), 589–600.
-
(2006)
Nat. Rev. Mol. Cell Biol.
, vol.7
, pp. 589-600
-
-
Heineke, J.1
Molkentin, J.D.2
-
76
-
-
23444440082
-
Long-term caloric restriction abrogates the age-related decline in skeletal muscle aerobic function
-
Hepple, R.T., Baker, D.J., Kaczor, J.J., Krause, D.J., Long-term caloric restriction abrogates the age-related decline in skeletal muscle aerobic function. FASEB J. 19 (2005), 1320–1322.
-
(2005)
FASEB J.
, vol.19
, pp. 1320-1322
-
-
Hepple, R.T.1
Baker, D.J.2
Kaczor, J.J.3
Krause, D.J.4
-
77
-
-
33744955359
-
Caloric restriction protects mitochondrial function with aging in skeletal and cardiac muscles
-
Hepple, R.T., Baker, D.J., McConkey, M., Murynka, T., Norris, R., Caloric restriction protects mitochondrial function with aging in skeletal and cardiac muscles. Rejuvenation Res. 9 (2006), 219–222.
-
(2006)
Rejuvenation Res.
, vol.9
, pp. 219-222
-
-
Hepple, R.T.1
Baker, D.J.2
McConkey, M.3
Murynka, T.4
Norris, R.5
-
78
-
-
57349126137
-
Caloric restriction optimizes the proteasome pathway with aging in rat plantaris muscle: implications for sarcopenia
-
Hepple, R.T., Qin, M., Nakamoto, H., Goto, S., Caloric restriction optimizes the proteasome pathway with aging in rat plantaris muscle: implications for sarcopenia. Am. J. Phys. Regul. Integr. Comp. Phys. 295 (2008), R1231–R1237.
-
(2008)
Am. J. Phys. Regul. Integr. Comp. Phys.
, vol.295
, pp. R1231-R1237
-
-
Hepple, R.T.1
Qin, M.2
Nakamoto, H.3
Goto, S.4
-
79
-
-
33644692330
-
Cellular senescence in aging primates
-
Herbig, U., Ferreira, M., Condel, L., Carey, D., Sedivy, J.M., Cellular senescence in aging primates. Science, 311, 2006, 1257.
-
(2006)
Science
, vol.311
, pp. 1257
-
-
Herbig, U.1
Ferreira, M.2
Condel, L.3
Carey, D.4
Sedivy, J.M.5
-
80
-
-
0028599744
-
Simplifying the complex - the paradigms of ecological function and structure
-
Holling, C.S., Simplifying the complex - the paradigms of ecological function and structure. Futures 26 (1994), 598–609.
-
(1994)
Futures
, vol.26
, pp. 598-609
-
-
Holling, C.S.1
-
81
-
-
0022410244
-
Effect of voluntary exercise on longevity of rats
-
(1985)
-
Holloszy, J.O., Smith, E.K., Vining, M., Adams, S., Effect of voluntary exercise on longevity of rats. J. Appl. Physiol. 59 (1985), 826–831 (1985).
-
(1985)
J. Appl. Physiol.
, vol.59
, pp. 826-831
-
-
Holloszy, J.O.1
Smith, E.K.2
Vining, M.3
Adams, S.4
-
82
-
-
46249094677
-
Rapamycin affects early fracture healing in mice
-
Holstein, J.H., Klein, M., Garcia, P., Histing, T., Culemann, U., Pizanis, A., Laschke, M.W., Scheuer, C., Meier, C., Schorr, H., Pohlemann, T., Menger, M.D., Rapamycin affects early fracture healing in mice. Br. J. Pharmacol. 154 (2008), 1055–1062.
-
(2008)
Br. J. Pharmacol.
, vol.154
, pp. 1055-1062
-
-
Holstein, J.H.1
Klein, M.2
Garcia, P.3
Histing, T.4
Culemann, U.5
Pizanis, A.6
Laschke, M.W.7
Scheuer, C.8
Meier, C.9
Schorr, H.10
Pohlemann, T.11
Menger, M.D.12
-
83
-
-
84861680444
-
Therapeutic validity and effectiveness of preoperative exercise on functional recovery after joint replacement: a systematic review and meta-analysis
-
e38031
-
Hoogeboom, T.J., Oosting, E., Vriezekolk, J.E., Veenhof, C., Siemonsma, P.C., de Bie, R.A., van den Ende, C.H., van Meeteren, N.L., Therapeutic validity and effectiveness of preoperative exercise on functional recovery after joint replacement: a systematic review and meta-analysis. PLoS One, 7, 2012, e38031.
-
(2012)
PLoS One
, vol.7
-
-
Hoogeboom, T.J.1
Oosting, E.2
Vriezekolk, J.E.3
Veenhof, C.4
Siemonsma, P.C.5
de Bie, R.A.6
van den Ende, C.H.7
van Meeteren, N.L.8
-
84
-
-
84896404621
-
Merits of exercise therapy before and after major surgery
-
Hoogeboom, T.J., Dronkers, J.J., Hulzebos, E.H., van Meeteren, N.L., Merits of exercise therapy before and after major surgery. Curr. Opin. Anaesthesiol. 27 (2014), 161–166.
-
(2014)
Curr. Opin. Anaesthesiol.
, vol.27
, pp. 161-166
-
-
Hoogeboom, T.J.1
Dronkers, J.J.2
Hulzebos, E.H.3
van Meeteren, N.L.4
-
85
-
-
84880147876
-
Hepatoprotective effects of swimming exercise against D-Galactose-induced senescence rat model
-
Huang, C.C., Chiang, W.D., Huang, W.C., Huang, C.Y., Hsu, M.C., Lin, W.T., Hepatoprotective effects of swimming exercise against D-Galactose-induced senescence rat model. Evid. Based Complement. Alternat. Med., 275431, 2013, 2013.
-
(2013)
Evid. Based Complement. Alternat. Med.
, pp. 2013
-
-
Huang, C.C.1
Chiang, W.D.2
Huang, W.C.3
Huang, C.Y.4
Hsu, M.C.5
Lin, W.T.6
-
86
-
-
84876481175
-
Effect of calorie restriction and refeeding on skin wound healing in the rat
-
Hunt, N.D., Li, G.D., Zhu, M., Miller, M., Levette, A., Chachich, M.E., Spangler, E.L., Allard, J.S., Hyun, D.H., Ingram, D.K., de Cabo, R., Effect of calorie restriction and refeeding on skin wound healing in the rat. Age (Dordr.) 34 (2012), 1453–1458.
-
(2012)
Age (Dordr.)
, vol.34
, pp. 1453-1458
-
-
Hunt, N.D.1
Li, G.D.2
Zhu, M.3
Miller, M.4
Levette, A.5
Chachich, M.E.6
Spangler, E.L.7
Allard, J.S.8
Hyun, D.H.9
Ingram, D.K.10
de Cabo, R.11
-
87
-
-
84901608730
-
Effect of metformin on periimplant wound healing in a rat model of type 2 diabetes
-
Inouye, K.A., Bisch, F.C., Elsalanty, M.E., Zakhary, I., Khashaba, R.M., Borke, J.L., Effect of metformin on periimplant wound healing in a rat model of type 2 diabetes. Implant. Dent. 23 (2014), 319–327.
-
(2014)
Implant. Dent.
, vol.23
, pp. 319-327
-
-
Inouye, K.A.1
Bisch, F.C.2
Elsalanty, M.E.3
Zakhary, I.4
Khashaba, R.M.5
Borke, J.L.6
-
88
-
-
80052981154
-
Perioperative exercise training in elderly subjects
-
Jack, S., West, M., Grocott, M.P., Perioperative exercise training in elderly subjects. Best Pract. Res. Clin. Anaesthesiol. 25 (2011), 461–472.
-
(2011)
Best Pract. Res. Clin. Anaesthesiol.
, vol.25
, pp. 461-472
-
-
Jack, S.1
West, M.2
Grocott, M.P.3
-
89
-
-
0031561513
-
Cancer chemopreventive activity of resveratrol, a natural product derived from grapes
-
Jang, M., Cai, L., Udeani, G.O., Slowing, K.V., Thomas, C.F., Beecher, C.W., Fong, H.H., Farnsworth, N.R., Kinghorn, A.D., Mehta, R.G., Moon, R.C., Pezzuto, J.M., Cancer chemopreventive activity of resveratrol, a natural product derived from grapes. Science 275 (1997), 218–220.
-
(1997)
Science
, vol.275
, pp. 218-220
-
-
Jang, M.1
Cai, L.2
Udeani, G.O.3
Slowing, K.V.4
Thomas, C.F.5
Beecher, C.W.6
Fong, H.H.7
Farnsworth, N.R.8
Kinghorn, A.D.9
Mehta, R.G.10
Moon, R.C.11
Pezzuto, J.M.12
-
90
-
-
0033927851
-
Skeletal muscle mass and distribution in 468 men and women aged 18-88 yr
-
Janssen, I., Heymsfield, S.B., Wang, Z.M., Ross, R., Skeletal muscle mass and distribution in 468 men and women aged 18-88 yr. J. Appl. Physiol. (1985) 89 (2000), 81–88.
-
(2000)
J. Appl. Physiol. (1985)
, vol.89
, pp. 81-88
-
-
Janssen, I.1
Heymsfield, S.B.2
Wang, Z.M.3
Ross, R.4
-
91
-
-
84885426684
-
The anti-diabetic drug metformin does not affect bone mass in vivo or fracture healing
-
Jeyabalan, J., Viollet, B., Smitham, P., Ellis, S.A., Zaman, G., Bardin, C., Goodship, A., Roux, J.P., Pierre, M., Chenu, C., The anti-diabetic drug metformin does not affect bone mass in vivo or fracture healing. Osteoporos. Int. 24 (2013), 2659–2670.
-
(2013)
Osteoporos. Int.
, vol.24
, pp. 2659-2670
-
-
Jeyabalan, J.1
Viollet, B.2
Smitham, P.3
Ellis, S.A.4
Zaman, G.5
Bardin, C.6
Goodship, A.7
Roux, J.P.8
Pierre, M.9
Chenu, C.10
-
92
-
-
84889005964
-
Metformin-stimulated AMPK-alpha1 promotes microvascular repair in acute lung injury
-
Jian, M.Y., Alexeyev, M.F., Wolkowicz, P.E., Zmijewski, J.W., Creighton, J.R., Metformin-stimulated AMPK-alpha1 promotes microvascular repair in acute lung injury. Am. J. Phys. Lung Cell. Mol. Phys. 305 (2013), L844–L855.
-
(2013)
Am. J. Phys. Lung Cell. Mol. Phys.
, vol.305
, pp. L844-L855
-
-
Jian, M.Y.1
Alexeyev, M.F.2
Wolkowicz, P.E.3
Zmijewski, J.W.4
Creighton, J.R.5
-
93
-
-
84885148256
-
Resveratrol improves adipose insulin signaling and reduces the inflammatory response in adipose tissue of rhesus monkeys on high-fat, high-sugar diet
-
Jimenez-Gomez, Y., Mattison, J.A., Pearson, K.J., Martin-Montalvo, A., Palacios, H.H., Sossong, A.M., Ward, T.M., Younts, C.M., Lewis, K., Allard, J.S., Longo, D.L., Belman, J.P., Malagon, M.M., Navas, P., Sanghvi, M., Moaddel, R., Tilmont, E.M., Herbert, R.L., Morrell, C.H., Egan, J.M., Baur, J.A., Ferrucci, L., Bogan, J.S., Bernier, M., de Cabo, R., Resveratrol improves adipose insulin signaling and reduces the inflammatory response in adipose tissue of rhesus monkeys on high-fat, high-sugar diet. Cell Metab. 18 (2013), 533–545.
-
(2013)
Cell Metab.
, vol.18
, pp. 533-545
-
-
Jimenez-Gomez, Y.1
Mattison, J.A.2
Pearson, K.J.3
Martin-Montalvo, A.4
Palacios, H.H.5
Sossong, A.M.6
Ward, T.M.7
Younts, C.M.8
Lewis, K.9
Allard, J.S.10
Longo, D.L.11
Belman, J.P.12
Malagon, M.M.13
Navas, P.14
Sanghvi, M.15
Moaddel, R.16
Tilmont, E.M.17
Herbert, R.L.18
Morrell, C.H.19
Egan, J.M.20
Baur, J.A.21
Ferrucci, L.22
Bogan, J.S.23
Bernier, M.24
de Cabo, R.25
more..
-
94
-
-
84874508918
-
Metformin: a cheap and well-tolerated drug that provides benefits for viral infections
-
Joven, J., Menendez, J.A., Fernandez-Sender, L., Espinel, E., Rull, A., Beltran-Debon, R., Rodriguez-Gallego, E., Riera-Borrull, M., Pedro-Botet, J., Alonso-Villaverde, C., Camps, J., Aragones, G., Metformin: a cheap and well-tolerated drug that provides benefits for viral infections. HIV Med. 14 (2013), 233–240.
-
(2013)
HIV Med.
, vol.14
, pp. 233-240
-
-
Joven, J.1
Menendez, J.A.2
Fernandez-Sender, L.3
Espinel, E.4
Rull, A.5
Beltran-Debon, R.6
Rodriguez-Gallego, E.7
Riera-Borrull, M.8
Pedro-Botet, J.9
Alonso-Villaverde, C.10
Camps, J.11
Aragones, G.12
-
95
-
-
84959930733
-
Impact of longevity interventions on a validated mouse clinical frailty index
-
Kane, A.E., Hilmer, S.N., Boyer, D., Gavin, K., Nines, D., Howlett, S.E., de Cabo, R., Mitchell, S.J., Impact of longevity interventions on a validated mouse clinical frailty index. J. Gerontol. A Biol. Sci. Med. Sci. 71 (2016), 333–339.
-
(2016)
J. Gerontol. A Biol. Sci. Med. Sci.
, vol.71
, pp. 333-339
-
-
Kane, A.E.1
Hilmer, S.N.2
Boyer, D.3
Gavin, K.4
Nines, D.5
Howlett, S.E.6
de Cabo, R.7
Mitchell, S.J.8
-
96
-
-
84887976550
-
The kinase mTOR modulates the antibody response to provide cross-protective immunity to lethal infection with influenza virus
-
Keating, R., Hertz, T., Wehenkel, M., Harris, T.L., Edwards, B.A., McClaren, J.L., Brown, S.A., Surman, S., Wilson, Z.S., Bradley, P., Hurwitz, J., Chi, H., Doherty, P.C., Thomas, P.G., McGargill, M.A., The kinase mTOR modulates the antibody response to provide cross-protective immunity to lethal infection with influenza virus. Nat. Immunol. 14 (2013), 1266–1276.
-
(2013)
Nat. Immunol.
, vol.14
, pp. 1266-1276
-
-
Keating, R.1
Hertz, T.2
Wehenkel, M.3
Harris, T.L.4
Edwards, B.A.5
McClaren, J.L.6
Brown, S.A.7
Surman, S.8
Wilson, Z.S.9
Bradley, P.10
Hurwitz, J.11
Chi, H.12
Doherty, P.C.13
Thomas, P.G.14
McGargill, M.A.15
-
97
-
-
84905970514
-
Metformin suppresses lipopolysaccharide (LPS)-induced inflammatory response in murine macrophages via activating transcription factor-3 (ATF-3) induction
-
Kim, J., Kwak, H.J., Cha, J.Y., Jeong, Y.S., Rhee, S.D., Kim, K.R., Cheon, H.G., Metformin suppresses lipopolysaccharide (LPS)-induced inflammatory response in murine macrophages via activating transcription factor-3 (ATF-3) induction. J. Biol. Chem. 289 (2014), 23246–23255.
-
(2014)
J. Biol. Chem.
, vol.289
, pp. 23246-23255
-
-
Kim, J.1
Kwak, H.J.2
Cha, J.Y.3
Jeong, Y.S.4
Rhee, S.D.5
Kim, K.R.6
Cheon, H.G.7
-
98
-
-
84943269357
-
Sirtuin1 suppresses Osteoclastogenesis by Deacetylating FoxOs
-
Kim, H.N., Han, L., Iyer, S., de Cabo, R., Zhao, H., O'Brien, C.A., Manolagas, S.C., Almeida, M., Sirtuin1 suppresses Osteoclastogenesis by Deacetylating FoxOs. Mol. Endocrinol. 29 (2015), 1498–1509.
-
(2015)
Mol. Endocrinol.
, vol.29
, pp. 1498-1509
-
-
Kim, H.N.1
Han, L.2
Iyer, S.3
de Cabo, R.4
Zhao, H.5
O'Brien, C.A.6
Manolagas, S.C.7
Almeida, M.8
-
99
-
-
67650071007
-
Effects of 7 days of exercise training on insulin sensitivity and responsiveness in type 2 diabetes mellitus
-
Kirwan, J.P., Solomon, T.P., Wojta, D.M., Staten, M.A., Holloszy, J.O., Effects of 7 days of exercise training on insulin sensitivity and responsiveness in type 2 diabetes mellitus. Am. J. Physiol. Endocrinol. Metab. 297 (2009), E151–E156.
-
(2009)
Am. J. Physiol. Endocrinol. Metab.
, vol.297
, pp. E151-E156
-
-
Kirwan, J.P.1
Solomon, T.P.2
Wojta, D.M.3
Staten, M.A.4
Holloszy, J.O.5
-
100
-
-
84881116641
-
Calorie restriction in overweight males ameliorates obesity-related metabolic alterations and cellular adaptations through anti-aging effects, possibly including AMPK and SIRT1 activation
-
Kitada, M., Kume, S., Takeda-Watanabe, A., Tsuda, S., Kanasaki, K., Koya, D., Calorie restriction in overweight males ameliorates obesity-related metabolic alterations and cellular adaptations through anti-aging effects, possibly including AMPK and SIRT1 activation. Biochim. Biophys. Acta 1830 (2013), 4820–4827.
-
(2013)
Biochim. Biophys. Acta
, vol.1830
, pp. 4820-4827
-
-
Kitada, M.1
Kume, S.2
Takeda-Watanabe, A.3
Tsuda, S.4
Kanasaki, K.5
Koya, D.6
-
101
-
-
34547450198
-
Risk factors for impaired wound healing in sirolimus-treated renal transplant recipients
-
Knight, R.J., Villa, M., Laskey, R., Benavides, C., Schoenberg, L., Welsh, M., Kerman, R.H., Podder, H., Van Buren, C.T., Katz, S.M., Kahan, B.D., Risk factors for impaired wound healing in sirolimus-treated renal transplant recipients. Clin. Transpl. 21 (2007), 460–465.
-
(2007)
Clin. Transpl.
, vol.21
, pp. 460-465
-
-
Knight, R.J.1
Villa, M.2
Laskey, R.3
Benavides, C.4
Schoenberg, L.5
Welsh, M.6
Kerman, R.H.7
Podder, H.8
Van Buren, C.T.9
Katz, S.M.10
Kahan, B.D.11
-
102
-
-
84925416071
-
Resveratrol prevents age-related memory and mood dysfunction with increased hippocampal neurogenesis and microvasculature, and reduced glial activation
-
Kodali, M., Parihar, V.K., Hattiangady, B., Mishra, V., Shuai, B., Shetty, A.K., Resveratrol prevents age-related memory and mood dysfunction with increased hippocampal neurogenesis and microvasculature, and reduced glial activation. Sci. Rep., 5, 2015, 8075.
-
(2015)
Sci. Rep.
, vol.5
, pp. 8075
-
-
Kodali, M.1
Parihar, V.K.2
Hattiangady, B.3
Mishra, V.4
Shuai, B.5
Shetty, A.K.6
-
103
-
-
23244443606
-
A single session of resistance exercise enhances insulin sensitivity for at least 24 h in healthy men
-
Koopman, R., Manders, R.J., Zorenc, A.H., Hul, G.B., Kuipers, H., Keizer, H.A., van Loon, L.J., A single session of resistance exercise enhances insulin sensitivity for at least 24 h in healthy men. Eur. J. Appl. Physiol. 94 (2005), 180–187.
-
(2005)
Eur. J. Appl. Physiol.
, vol.94
, pp. 180-187
-
-
Koopman, R.1
Manders, R.J.2
Zorenc, A.H.3
Hul, G.B.4
Kuipers, H.5
Keizer, H.A.6
van Loon, L.J.7
-
104
-
-
17844384537
-
Hormonal responses and adaptations to resistance exercise and training
-
Kraemer, W.J., Ratamess, N.A., Hormonal responses and adaptations to resistance exercise and training. Sports Med. 35 (2005), 339–361.
-
(2005)
Sports Med.
, vol.35
, pp. 339-361
-
-
Kraemer, W.J.1
Ratamess, N.A.2
-
105
-
-
84900969225
-
Ink4a/Arf expression is a biomarker of aging
-
Krishnamurthy, J., Torrice, C., Ramsey, M.R., Kovalev, G.I., Al-Regaiey, K., Su, L., Sharpless, N.E., Ink4a/Arf expression is a biomarker of aging. J. Clin. Invest. 114 (2004), 1299–1307.
-
(2004)
J. Clin. Invest.
, vol.114
, pp. 1299-1307
-
-
Krishnamurthy, J.1
Torrice, C.2
Ramsey, M.R.3
Kovalev, G.I.4
Al-Regaiey, K.5
Su, L.6
Sharpless, N.E.7
-
106
-
-
36248998279
-
Chronic calorie restriction increases susceptibility of laboratory mice (Mus musculus) to a primary intestinal parasite infection
-
Kristan, D.M., Chronic calorie restriction increases susceptibility of laboratory mice (Mus musculus) to a primary intestinal parasite infection. Aging Cell 6 (2007), 817–825.
-
(2007)
Aging Cell
, vol.6
, pp. 817-825
-
-
Kristan, D.M.1
-
107
-
-
50949120511
-
Calorie restriction and susceptibility to intact pathogens
-
Kristan, D.M., Calorie restriction and susceptibility to intact pathogens. Age (Dordr.) 30 (2008), 147–156.
-
(2008)
Age (Dordr.)
, vol.30
, pp. 147-156
-
-
Kristan, D.M.1
-
108
-
-
33748188974
-
Physical exercise prevents age-related decline in precursor cell activity in the mouse dentate gyrus
-
Kronenberg, G., Bick-Sander, A., Bunk, E., Wolf, C., Ehninger, D., Kempermann, G., Physical exercise prevents age-related decline in precursor cell activity in the mouse dentate gyrus. Neurobiol. Aging 27 (2006), 1505–1513.
-
(2006)
Neurobiol. Aging
, vol.27
, pp. 1505-1513
-
-
Kronenberg, G.1
Bick-Sander, A.2
Bunk, E.3
Wolf, C.4
Ehninger, D.5
Kempermann, G.6
-
109
-
-
84859117806
-
Rapamycin-induced insulin resistance is mediated by mTORC2 loss and uncoupled from longevity
-
Lamming, D.W., Ye, L., Katajisto, P., Goncalves, M.D., Saitoh, M., Stevens, D.M., Davis, J.G., Salmon, A.B., Richardson, A., Ahima, R.S., Guertin, D.A., Sabatini, D.M., Baur, J.A., Rapamycin-induced insulin resistance is mediated by mTORC2 loss and uncoupled from longevity. Science 335 (2012), 1638–1643.
-
(2012)
Science
, vol.335
, pp. 1638-1643
-
-
Lamming, D.W.1
Ye, L.2
Katajisto, P.3
Goncalves, M.D.4
Saitoh, M.5
Stevens, D.M.6
Davis, J.G.7
Salmon, A.B.8
Richardson, A.9
Ahima, R.S.10
Guertin, D.A.11
Sabatini, D.M.12
Baur, J.A.13
-
110
-
-
84874611570
-
Rapalogs and mTOR inhibitors as anti-aging therapeutics
-
Lamming, D.W., Ye, L., Sabatini, D.M., Baur, J.A., Rapalogs and mTOR inhibitors as anti-aging therapeutics. J. Clin. Invest. 123 (2013), 980–989.
-
(2013)
J. Clin. Invest.
, vol.123
, pp. 980-989
-
-
Lamming, D.W.1
Ye, L.2
Sabatini, D.M.3
Baur, J.A.4
-
111
-
-
33746419647
-
Effect of calorie restriction with or without exercise on insulin sensitivity, beta-cell function, fat cell size, and ectopic lipid in overweight subjects
-
Larson-Meyer, D.E., Heilbronn, L.K., Redman, L.M., Newcomer, B.R., Frisard, M.I., Anton, S., Smith, S.R., Alfonso, A., Ravussin, E., Effect of calorie restriction with or without exercise on insulin sensitivity, beta-cell function, fat cell size, and ectopic lipid in overweight subjects. Diabetes Care 29 (2006), 1337–1344.
-
(2006)
Diabetes Care
, vol.29
, pp. 1337-1344
-
-
Larson-Meyer, D.E.1
Heilbronn, L.K.2
Redman, L.M.3
Newcomer, B.R.4
Frisard, M.I.5
Anton, S.6
Smith, S.R.7
Alfonso, A.8
Ravussin, E.9
-
112
-
-
84947241738
-
Cellular senescence and the biology of aging, disease, and frailty
-
LeBrasseur, N.K., Tchkonia, T., Kirkland, J.L., Cellular senescence and the biology of aging, disease, and frailty. Nestle Nutr. Inst. Workshop Ser. 83 (2015), 11–18.
-
(2015)
Nestle Nutr. Inst. Workshop Ser.
, vol.83
, pp. 11-18
-
-
LeBrasseur, N.K.1
Tchkonia, T.2
Kirkland, J.L.3
-
113
-
-
79960845908
-
Fasting vs dietary restriction in cellular protection and cancer treatment: from model organisms to patients
-
Lee, C., Longo, V.D., Fasting vs dietary restriction in cellular protection and cancer treatment: from model organisms to patients. Oncogene 30 (2011), 3305–3316.
-
(2011)
Oncogene
, vol.30
, pp. 3305-3316
-
-
Lee, C.1
Longo, V.D.2
-
114
-
-
76749169812
-
Reduced levels of IGF-I mediate differential protection of normal and cancer cells in response to fasting and improve chemotherapeutic index
-
Lee, C., Safdie, F.M., Raffaghello, L., Wei, M., Madia, F., Parrella, E., Hwang, D., Cohen, P., Bianchi, G., Longo, V.D., Reduced levels of IGF-I mediate differential protection of normal and cancer cells in response to fasting and improve chemotherapeutic index. Cancer Res. 70 (2010), 1564–1572.
-
(2010)
Cancer Res.
, vol.70
, pp. 1564-1572
-
-
Lee, C.1
Safdie, F.M.2
Raffaghello, L.3
Wei, M.4
Madia, F.5
Parrella, E.6
Hwang, D.7
Cohen, P.8
Bianchi, G.9
Longo, V.D.10
-
115
-
-
84870605931
-
Chronic resveratrol treatment protects pancreatic islets against oxidative stress in db/db mice
-
e50412
-
Lee, Y.E., Kim, J.W., Lee, E.M., Ahn, Y.B., Song, K.H., Yoon, K.H., Kim, H.W., Park, C.W., Li, G., Liu, Z., Ko, S.H., Chronic resveratrol treatment protects pancreatic islets against oxidative stress in db/db mice. PLoS One, 7, 2012, e50412.
-
(2012)
PLoS One
, vol.7
-
-
Lee, Y.E.1
Kim, J.W.2
Lee, E.M.3
Ahn, Y.B.4
Song, K.H.5
Yoon, K.H.6
Kim, H.W.7
Park, C.W.8
Li, G.9
Liu, Z.10
Ko, S.H.11
-
116
-
-
84863229916
-
Fasting cycles retard growth of tumors and sensitize a range of cancer cell types to chemotherapy
-
124ra127
-
Lee, C., Raffaghello, L., Brandhorst, S., Safdie, F.M., Bianchi, G., Martin-Montalvo, A., Pistoia, V., Wei, M., Hwang, S., Merlino, A., Emionite, L., de Cabo, R., Longo, V.D., Fasting cycles retard growth of tumors and sensitize a range of cancer cell types to chemotherapy. Sci. Transl. Med., 4, 2012, 124ra127.
-
(2012)
Sci. Transl. Med.
, vol.4
-
-
Lee, C.1
Raffaghello, L.2
Brandhorst, S.3
Safdie, F.M.4
Bianchi, G.5
Martin-Montalvo, A.6
Pistoia, V.7
Wei, M.8
Hwang, S.9
Merlino, A.10
Emionite, L.11
de Cabo, R.12
Longo, V.D.13
-
117
-
-
84885451683
-
Inhibition of breast cancer metastasis by resveratrol-mediated inactivation of tumor-evoked regulatory B cells
-
Lee-Chang, C., Bodogai, M., Martin-Montalvo, A., Wejksza, K., Sanghvi, M., Moaddel, R., de Cabo, R., Biragyn, A., Inhibition of breast cancer metastasis by resveratrol-mediated inactivation of tumor-evoked regulatory B cells. J. Immunol. 191 (2013), 4141–4151.
-
(2013)
J. Immunol.
, vol.191
, pp. 4141-4151
-
-
Lee-Chang, C.1
Bodogai, M.2
Martin-Montalvo, A.3
Wejksza, K.4
Sanghvi, M.5
Moaddel, R.6
de Cabo, R.7
Biragyn, A.8
-
118
-
-
84895727751
-
Low protein intake is associated with a major reduction in IGF-1, cancer, and overall mortality in the 65 and younger but not older population
-
Levine, M.E., Suarez, J.A., Brandhorst, S., Balasubramanian, P., Cheng, C.W., Madia, F., Fontana, L., Mirisola, M.G., Guevara-Aguirre, J., Wan, J., Passarino, G., Kennedy, B.K., Wei, M., Cohen, P., Crimmins, E.M., Longo, V.D., Low protein intake is associated with a major reduction in IGF-1, cancer, and overall mortality in the 65 and younger but not older population. Cell Metab. 19 (2014), 407–417.
-
(2014)
Cell Metab.
, vol.19
, pp. 407-417
-
-
Levine, M.E.1
Suarez, J.A.2
Brandhorst, S.3
Balasubramanian, P.4
Cheng, C.W.5
Madia, F.6
Fontana, L.7
Mirisola, M.G.8
Guevara-Aguirre, J.9
Wan, J.10
Passarino, G.11
Kennedy, B.K.12
Wei, M.13
Cohen, P.14
Crimmins, E.M.15
Longo, V.D.16
-
119
-
-
0023856536
-
What is the cause of the ageing atrophy? Total number, size and proportion of different fiber types studied in whole vastus lateralis muscle from 15- to 83-year-old men
-
Lexell, J., Taylor, C.C., Sjostrom, M., What is the cause of the ageing atrophy? Total number, size and proportion of different fiber types studied in whole vastus lateralis muscle from 15- to 83-year-old men. J. Neurol. Sci. 84 (1988), 275–294.
-
(1988)
J. Neurol. Sci.
, vol.84
, pp. 275-294
-
-
Lexell, J.1
Taylor, C.C.2
Sjostrom, M.3
-
120
-
-
76249097841
-
Genetic variation in the murine lifespan response to dietary restriction: from life extension to life shortening
-
Liao, C.Y., Rikke, B.A., Johnson, T.E., Diaz, V., Nelson, J.F., Genetic variation in the murine lifespan response to dietary restriction: from life extension to life shortening. Aging Cell 9 (2010), 92–95.
-
(2010)
Aging Cell
, vol.9
, pp. 92-95
-
-
Liao, C.Y.1
Rikke, B.A.2
Johnson, T.E.3
Diaz, V.4
Nelson, J.F.5
-
121
-
-
84865065336
-
The role of AMPK/mTOR/S6 K1 signaling axis in mediating the physiological process of exercise-induced insulin sensitization in skeletal muscle of C57BL/6 mice
-
Liu, X., Yuan, H., Niu, Y., Niu, W., Fu, L., The role of AMPK/mTOR/S6 K1 signaling axis in mediating the physiological process of exercise-induced insulin sensitization in skeletal muscle of C57BL/6 mice. Biochim. Biophys. Acta 1822 (2012), 1716–1726.
-
(2012)
Biochim. Biophys. Acta
, vol.1822
, pp. 1716-1726
-
-
Liu, X.1
Yuan, H.2
Niu, Y.3
Niu, W.4
Fu, L.5
-
122
-
-
84927961920
-
AMPK binds to Sestrins and mediates the effect of exercise to increase insulin-sensitivity through autophagy
-
Liu, X., Niu, Y., Yuan, H., Huang, J., Fu, L., AMPK binds to Sestrins and mediates the effect of exercise to increase insulin-sensitivity through autophagy. Metabolism 64 (2015), 658–665.
-
(2015)
Metabolism
, vol.64
, pp. 658-665
-
-
Liu, X.1
Niu, Y.2
Yuan, H.3
Huang, J.4
Fu, L.5
-
123
-
-
84956872444
-
Resveratrol protects cardiomyocytes from doxorubicininduced apoptosis through the AMPK/P53 pathway
-
Liu, M.H., Lin, X.L., Guo, D.M., Zhang, Y., Yuan, C., Tan, T.P., Chen, Y.D., Wu, S.J., Ye, Z.F., He, J., Resveratrol protects cardiomyocytes from doxorubicininduced apoptosis through the AMPK/P53 pathway. Mol. Med. Rep. 13 (2016), 1281–1286.
-
(2016)
Mol. Med. Rep.
, vol.13
, pp. 1281-1286
-
-
Liu, M.H.1
Lin, X.L.2
Guo, D.M.3
Zhang, Y.4
Yuan, C.5
Tan, T.P.6
Chen, Y.D.7
Wu, S.J.8
Ye, Z.F.9
He, J.10
-
124
-
-
0036306657
-
Regulation of longevity and stress resistance: a molecular strategy conserved from yeast to humans?
-
Longo, V.D., Fabrizio, P., Regulation of longevity and stress resistance: a molecular strategy conserved from yeast to humans?. Cell. Mol. Life Sci. 59 (2002), 903–908.
-
(2002)
Cell. Mol. Life Sci.
, vol.59
, pp. 903-908
-
-
Longo, V.D.1
Fabrizio, P.2
-
125
-
-
75249094454
-
Calorie restriction and cancer prevention: metabolic and molecular mechanisms
-
Longo, V.D., Fontana, L., Calorie restriction and cancer prevention: metabolic and molecular mechanisms. Trends Pharmacol. Sci. 31 (2010), 89–98.
-
(2010)
Trends Pharmacol. Sci.
, vol.31
, pp. 89-98
-
-
Longo, V.D.1
Fontana, L.2
-
126
-
-
84878864199
-
The hallmarks of aging
-
Lopez-Otin, C., Blasco, M.A., Partridge, L., Serrano, M., Kroemer, G., The hallmarks of aging. Cell 153 (2013), 1194–1217.
-
(2013)
Cell
, vol.153
, pp. 1194-1217
-
-
Lopez-Otin, C.1
Blasco, M.A.2
Partridge, L.3
Serrano, M.4
Kroemer, G.5
-
127
-
-
84938072752
-
Resveratrol prevents doxorubicin-induced cardiotoxicity in H9c2 cells through the inhibition of endoplasmic reticulum stress and the activation of the Sirt1 pathway
-
Lou, Y., Wang, Z., Xu, Y., Zhou, P., Cao, J., Li, Y., Chen, Y., Sun, J., Fu, L., Resveratrol prevents doxorubicin-induced cardiotoxicity in H9c2 cells through the inhibition of endoplasmic reticulum stress and the activation of the Sirt1 pathway. Int. J. Mol. Med. 36 (2015), 873–880.
-
(2015)
Int. J. Mol. Med.
, vol.36
, pp. 873-880
-
-
Lou, Y.1
Wang, Z.2
Xu, Y.3
Zhou, P.4
Cao, J.5
Li, Y.6
Chen, Y.7
Sun, J.8
Fu, L.9
-
128
-
-
84878227058
-
BDNF-based synaptic repair as a disease-modifying strategy for neurodegenerative diseases
-
Lu, B., et al. BDNF-based synaptic repair as a disease-modifying strategy for neurodegenerative diseases. Nature reviews. Neuroscience 14:6 (2013), 401–416.
-
(2013)
Nature reviews. Neuroscience
, vol.14
, Issue.6
, pp. 401-416
-
-
Lu, B.1
-
129
-
-
84919756169
-
mTOR inhibition improves immune function in the elderly
-
268ra179
-
Mannick, J.B., Del Giudice, G., Lattanzi, M., Valiante, N.M., Praestgaard, J., Huang, B., Lonetto, M.A., Maecker, H.T., Kovarik, J., Carson, S., Glass, D.J., Klickstein, L.B., mTOR inhibition improves immune function in the elderly. Sci. Transl. Med., 6, 2014, 268ra179.
-
(2014)
Sci. Transl. Med.
, vol.6
-
-
Mannick, J.B.1
Del Giudice, G.2
Lattanzi, M.3
Valiante, N.M.4
Praestgaard, J.5
Huang, B.6
Lonetto, M.A.7
Maecker, H.T.8
Kovarik, J.9
Carson, S.10
Glass, D.J.11
Klickstein, L.B.12
-
130
-
-
84903530938
-
The anti-diabetic drug metformin protects against chemotherapy-induced peripheral neuropathy in a mouse model
-
e100701
-
Mao-Ying, Q.L., Kavelaars, A., Krukowski, K., Huo, X.J., Zhou, W., Price, T.J., Cleeland, C., Heijnen, C.J., The anti-diabetic drug metformin protects against chemotherapy-induced peripheral neuropathy in a mouse model. PLoS One, 9, 2014, e100701.
-
(2014)
PLoS One
, vol.9
-
-
Mao-Ying, Q.L.1
Kavelaars, A.2
Krukowski, K.3
Huo, X.J.4
Zhou, W.5
Price, T.J.6
Cleeland, C.7
Heijnen, C.J.8
-
131
-
-
84924094844
-
Effect of age on basal muscle protein synthesis and mTORC1 signaling in a large cohort of young and older men and women
-
Markofski, M.M., Dickinson, J.M., Drummond, M.J., Fry, C.S., Fujita, S., Gundermann, D.M., Glynn, E.L., Jennings, K., Paddon-Jones, D., Reidy, P.T., Sheffield-Moore, M., Timmerman, K.L., Rasmussen, B.B., Volpi, E., Effect of age on basal muscle protein synthesis and mTORC1 signaling in a large cohort of young and older men and women. Exp. Gerontol. 65 (2015), 1–7.
-
(2015)
Exp. Gerontol.
, vol.65
, pp. 1-7
-
-
Markofski, M.M.1
Dickinson, J.M.2
Drummond, M.J.3
Fry, C.S.4
Fujita, S.5
Gundermann, D.M.6
Glynn, E.L.7
Jennings, K.8
Paddon-Jones, D.9
Reidy, P.T.10
Sheffield-Moore, M.11
Timmerman, K.L.12
Rasmussen, B.B.13
Volpi, E.14
-
132
-
-
84881347302
-
Metformin improves healthspan and lifespan in mice
-
Martin-Montalvo, A., Mercken, E.M., Mitchell, S.J., Palacios, H.H., Mote, P.L., Scheibye-Knudsen, M., Gomes, A.P., Ward, T.M., Minor, R.K., Blouin, M.J., Schwab, M., Pollak, M., Zhang, Y., Yu, Y., Becker, K.G., Bohr, V.A., Ingram, D.K., Sinclair, D.A., Wolf, N.S., Spindler, S.R., Bernier, M., de Cabo, R., Metformin improves healthspan and lifespan in mice. Nat. Commun., 4, 2013, 2192.
-
(2013)
Nat. Commun.
, vol.4
, pp. 2192
-
-
Martin-Montalvo, A.1
Mercken, E.M.2
Mitchell, S.J.3
Palacios, H.H.4
Mote, P.L.5
Scheibye-Knudsen, M.6
Gomes, A.P.7
Ward, T.M.8
Minor, R.K.9
Blouin, M.J.10
Schwab, M.11
Pollak, M.12
Zhang, Y.13
Yu, Y.14
Becker, K.G.15
Bohr, V.A.16
Ingram, D.K.17
Sinclair, D.A.18
Wolf, N.S.19
Spindler, S.R.20
Bernier, M.21
de Cabo, R.22
more..
-
133
-
-
0031984854
-
Hormesis and the antiaging action of dietary restriction
-
Masoro, E.J., Hormesis and the antiaging action of dietary restriction. Exp. Gerontol. 33 (1998), 61–66.
-
(1998)
Exp. Gerontol.
, vol.33
, pp. 61-66
-
-
Masoro, E.J.1
-
134
-
-
84904063673
-
Resveratrol prevents high fat/sucrose diet-induced central arterial wall inflammation and stiffening in nonhuman primates
-
Mattison, J.A., Wang, M., Bernier, M., Zhang, J., Park, S.S., Maudsley, S., An, S.S., Santhanam, L., Martin, B., Faulkner, S., Morrell, C., Baur, J.A., Peshkin, L., Sosnowska, D., Csiszar, A., Herbert, R.L., Tilmont, E.M., Ungvari, Z., Pearson, K.J., Lakatta, E.G., de Cabo, R., Resveratrol prevents high fat/sucrose diet-induced central arterial wall inflammation and stiffening in nonhuman primates. Cell Metab. 20 (2014), 183–190.
-
(2014)
Cell Metab.
, vol.20
, pp. 183-190
-
-
Mattison, J.A.1
Wang, M.2
Bernier, M.3
Zhang, J.4
Park, S.S.5
Maudsley, S.6
An, S.S.7
Santhanam, L.8
Martin, B.9
Faulkner, S.10
Morrell, C.11
Baur, J.A.12
Peshkin, L.13
Sosnowska, D.14
Csiszar, A.15
Herbert, R.L.16
Tilmont, E.M.17
Ungvari, Z.18
Pearson, K.J.19
Lakatta, E.G.20
de Cabo, R.21
more..
-
135
-
-
84857417374
-
Differential effects of energy balance on experimentally-induced colitis
-
McCaskey, S.J., Rondini, E.A., Langohr, I.M., Fenton, J.I., Differential effects of energy balance on experimentally-induced colitis. World J. Gastroenterol. 18 (2012), 627–636.
-
(2012)
World J. Gastroenterol.
, vol.18
, pp. 627-636
-
-
McCaskey, S.J.1
Rondini, E.A.2
Langohr, I.M.3
Fenton, J.I.4
-
136
-
-
84863393612
-
Cellular adaptation contributes to calorie restriction-induced preservation of skeletal muscle in aged rhesus monkeys
-
McKiernan, S.H., Colman, R.J., Aiken, E., Evans, T.D., Beasley, T.M., Aiken, J.M., Weindruch, R., Anderson, R.M., Cellular adaptation contributes to calorie restriction-induced preservation of skeletal muscle in aged rhesus monkeys. Exp. Gerontol. 47 (2012), 229–236.
-
(2012)
Exp. Gerontol.
, vol.47
, pp. 229-236
-
-
McKiernan, S.H.1
Colman, R.J.2
Aiken, E.3
Evans, T.D.4
Beasley, T.M.5
Aiken, J.M.6
Weindruch, R.7
Anderson, R.M.8
-
137
-
-
30344435943
-
Long-term caloric restriction ameliorates the decline in diastolic function in humans
-
Meyer, T.E., Kovacs, S.J., Ehsani, A.A., Klein, S., Holloszy, J.O., Fontana, L., Long-term caloric restriction ameliorates the decline in diastolic function in humans. J. Am. Coll. Cardiol. 47 (2006), 398–402.
-
(2006)
J. Am. Coll. Cardiol.
, vol.47
, pp. 398-402
-
-
Meyer, T.E.1
Kovacs, S.J.2
Ehsani, A.A.3
Klein, S.4
Holloszy, J.O.5
Fontana, L.6
-
138
-
-
23844464540
-
Methionine-deficient diet extends mouse lifespan, slows immune and lens aging, alters glucose, T4, IGF-I and insulin levels, and increases hepatocyte MIF levels and stress resistance
-
Miller, R.A., Buehner, G., Chang, Y., Harper, J.M., Sigler, R., Smith-Wheelock, M., Methionine-deficient diet extends mouse lifespan, slows immune and lens aging, alters glucose, T4, IGF-I and insulin levels, and increases hepatocyte MIF levels and stress resistance. Aging Cell 4 (2005), 119–125.
-
(2005)
Aging Cell
, vol.4
, pp. 119-125
-
-
Miller, R.A.1
Buehner, G.2
Chang, Y.3
Harper, J.M.4
Sigler, R.5
Smith-Wheelock, M.6
-
139
-
-
76249106732
-
Short-term dietary restriction and fasting precondition against ischemia reperfusion injury in mice
-
Mitchell, J.R., Verweij, M., Brand, K., van de Ven, M., Goemaere, N., van den Engel, S., Chu, T., Forrer, F., Muller, C., de Jong, M., van IJcken, W., IJzermans, J.N., Hoeijmakers, J.H., de Bruin, R.W., Short-term dietary restriction and fasting precondition against ischemia reperfusion injury in mice. Aging Cell 9 (2010), 40–53.
-
(2010)
Aging Cell
, vol.9
, pp. 40-53
-
-
Mitchell, J.R.1
Verweij, M.2
Brand, K.3
van de Ven, M.4
Goemaere, N.5
van den Engel, S.6
Chu, T.7
Forrer, F.8
Muller, C.9
de Jong, M.10
van IJcken, W.11
IJzermans, J.N.12
Hoeijmakers, J.H.13
de Bruin, R.W.14
-
140
-
-
84870267022
-
Leisure time physical activity of moderate to vigorous intensity and mortality: a large pooled cohort analysis
-
e1001335
-
Moore, S.C., Patel, A.V., Matthews, C.E., Berrington de Gonzalez, A., Park, Y., Katki, H.A., Linet, M.S., Weiderpass, E., Visvanathan, K., Helzlsouer, K.J., Thun, M., Gapstur, S.M., Hartge, P., Lee, I.M., Leisure time physical activity of moderate to vigorous intensity and mortality: a large pooled cohort analysis. PLoS Med., 9, 2012, e1001335.
-
(2012)
PLoS Med.
, vol.9
-
-
Moore, S.C.1
Patel, A.V.2
Matthews, C.E.3
Berrington de Gonzalez, A.4
Park, Y.5
Katki, H.A.6
Linet, M.S.7
Weiderpass, E.8
Visvanathan, K.9
Helzlsouer, K.J.10
Thun, M.11
Gapstur, S.M.12
Hartge, P.13
Lee, I.M.14
-
141
-
-
84921405225
-
Metformin in cancer treatment and prevention
-
Morales, D.R., Morris, A.D., Metformin in cancer treatment and prevention. Annu. Rev. Med. 66 (2015), 17–29.
-
(2015)
Annu. Rev. Med.
, vol.66
, pp. 17-29
-
-
Morales, D.R.1
Morris, A.D.2
-
142
-
-
84904702784
-
Cellular senescence: from physiology to pathology
-
Munoz-Espin, D., Serrano, M., Cellular senescence: from physiology to pathology. Nat. Rev. Mol. Cell Biol. 15 (2014), 482–496.
-
(2014)
Nat. Rev. Mol. Cell Biol.
, vol.15
, pp. 482-496
-
-
Munoz-Espin, D.1
Serrano, M.2
-
143
-
-
52949151145
-
Exercise stress increases susceptibility to influenza infection
-
Murphy, E.A., Davis, J.M., Carmichael, M.D., Gangemi, J.D., Ghaffar, A., Mayer, E.P., Exercise stress increases susceptibility to influenza infection. Brain Behav. Immun. 22 (2008), 1152–1155.
-
(2008)
Brain Behav. Immun.
, vol.22
, pp. 1152-1155
-
-
Murphy, E.A.1
Davis, J.M.2
Carmichael, M.D.3
Gangemi, J.D.4
Ghaffar, A.5
Mayer, E.P.6
-
144
-
-
84923303163
-
Importance of exercise capacity in predicting outcomes and determining optimal timing of surgery in significant primary mitral regurgitation
-
e001010
-
Naji, P., Griffin, B.P., Barr, T., Asfahan, F., Gillinov, A.M., Grimm, R.A., Rodriguez, L.L., Mihaljevic, T., Stewart, W.J., Desai, M.Y., Importance of exercise capacity in predicting outcomes and determining optimal timing of surgery in significant primary mitral regurgitation. J. Am. Heart Assoc., 3, 2014, e001010.
-
(2014)
J. Am. Heart Assoc.
, vol.3
-
-
Naji, P.1
Griffin, B.P.2
Barr, T.3
Asfahan, F.4
Gillinov, A.M.5
Grimm, R.A.6
Rodriguez, L.L.7
Mihaljevic, T.8
Stewart, W.J.9
Desai, M.Y.10
-
145
-
-
33847682666
-
Regular exercise reduces 8-oxodG in the nuclear and mitochondrial DNA and modulates the DNA repair activity in the liver of old rats
-
Nakamoto, H., Kaneko, T., Tahara, S., Hayashi, E., Naito, H., Radak, Z., Goto, S., Regular exercise reduces 8-oxodG in the nuclear and mitochondrial DNA and modulates the DNA repair activity in the liver of old rats. Exp. Gerontol. 42 (2007), 287–295.
-
(2007)
Exp. Gerontol.
, vol.42
, pp. 287-295
-
-
Nakamoto, H.1
Kaneko, T.2
Tahara, S.3
Hayashi, E.4
Naito, H.5
Radak, Z.6
Goto, S.7
-
146
-
-
84866731714
-
Wound healing complications and the use of mammalian target of rapamycin inhibitors in kidney transplantation: a critical review of the literature
-
Nashan, B., Citterio, F., Wound healing complications and the use of mammalian target of rapamycin inhibitors in kidney transplantation: a critical review of the literature. Transplantation 94 (2012), 547–561.
-
(2012)
Transplantation
, vol.94
, pp. 547-561
-
-
Nashan, B.1
Citterio, F.2
-
147
-
-
84881247539
-
Rapamycin extends murine lifespan but has limited effects on aging
-
Neff, F., Flores-Dominguez, D., Ryan, D.P., Horsch, M., Schroder, S., Adler, T., Afonso, L.C., Aguilar-Pimentel, J.A., Becker, L., Garrett, L., Hans, W., Hettich, M.M., Holtmeier, R., Holter, S.M., Moreth, K., Prehn, C., Puk, O., Racz, I., Rathkolb, B., Rozman, J., Naton, B., Ordemann, R., Adamski, J., Beckers, J., Bekeredjian, R., Busch, D.H., Ehninger, G., Graw, J., Hofler, H., Klingenspor, M., Klopstock, T., Ollert, M., Stypmann, J., Wolf, E., Wurst, W., Zimmer, A., Fuchs, H., Gailus-Durner, V., Hrabe de Angelis, M., Ehninger, D., Rapamycin extends murine lifespan but has limited effects on aging. J. Clin. Invest. 123 (2013), 3272–3291.
-
(2013)
J. Clin. Invest.
, vol.123
, pp. 3272-3291
-
-
Neff, F.1
Flores-Dominguez, D.2
Ryan, D.P.3
Horsch, M.4
Schroder, S.5
Adler, T.6
Afonso, L.C.7
Aguilar-Pimentel, J.A.8
Becker, L.9
Garrett, L.10
Hans, W.11
Hettich, M.M.12
Holtmeier, R.13
Holter, S.M.14
Moreth, K.15
Prehn, C.16
Puk, O.17
Racz, I.18
Rathkolb, B.19
Rozman, J.20
Naton, B.21
Ordemann, R.22
Adamski, J.23
Beckers, J.24
Bekeredjian, R.25
Busch, D.H.26
Ehninger, G.27
Graw, J.28
Hofler, H.29
Klingenspor, M.30
Klopstock, T.31
Ollert, M.32
Stypmann, J.33
Wolf, E.34
Wurst, W.35
Zimmer, A.36
Fuchs, H.37
Gailus-Durner, V.38
Hrabe de Angelis, M.39
Ehninger, D.40
more..
-
148
-
-
84961231063
-
Metformin induces cell cycle arrest, reduced proliferation, wound healing impairment in vivo and is associated to clinical outcomes in diabetic foot ulcer patients
-
e0150900
-
Ochoa-Gonzalez, F., Cervantes-Villagrana, A.R., Fernandez-Ruiz, J.C., Nava-Ramirez, H.S., Hernandez-Correa, A.C., Enciso-Moreno, J.A., Castaneda-Delgado, J.E., Metformin induces cell cycle arrest, reduced proliferation, wound healing impairment in vivo and is associated to clinical outcomes in diabetic foot ulcer patients. PLoS One, 11, 2016, e0150900.
-
(2016)
PLoS One
, vol.11
-
-
Ochoa-Gonzalez, F.1
Cervantes-Villagrana, A.R.2
Fernandez-Ruiz, J.C.3
Nava-Ramirez, H.S.4
Hernandez-Correa, A.C.5
Enciso-Moreno, J.A.6
Castaneda-Delgado, J.E.7
-
149
-
-
33750918305
-
Exercise training increases insulin-stimulated glucose disposal and GLUT4 (SLC2A4) protein content in patients with type 2 diabetes
-
O'Gorman, D.J., Karlsson, H.K., McQuaid, S., Yousif, O., Rahman, Y., Gasparro, D., Glund, S., Chibalin, A.V., Zierath, J.R., Nolan, J.J., Exercise training increases insulin-stimulated glucose disposal and GLUT4 (SLC2A4) protein content in patients with type 2 diabetes. Diabetologia 49 (2006), 2983–2992.
-
(2006)
Diabetologia
, vol.49
, pp. 2983-2992
-
-
O'Gorman, D.J.1
Karlsson, H.K.2
McQuaid, S.3
Yousif, O.4
Rahman, Y.5
Gasparro, D.6
Glund, S.7
Chibalin, A.V.8
Zierath, J.R.9
Nolan, J.J.10
-
150
-
-
77649311383
-
Metformin induces a dietary restriction-like state and the oxidative stress response to extend C. elegans Healthspan via AMPK, LKB1, and SKN-1
-
e8758
-
Onken, B., Driscoll, M., Metformin induces a dietary restriction-like state and the oxidative stress response to extend C. elegans Healthspan via AMPK, LKB1, and SKN-1. PLoS One, 5, 2010, e8758.
-
(2010)
PLoS One
, vol.5
-
-
Onken, B.1
Driscoll, M.2
-
151
-
-
17144389303
-
The effect of metformin and intensive lifestyle intervention on the metabolic syndrome: the diabetes prevention program randomized trial
-
Orchard, T.J., Temprosa, M., Goldberg, R., Haffner, S., Ratner, R., Marcovina, S., Fowler, S., The effect of metformin and intensive lifestyle intervention on the metabolic syndrome: the diabetes prevention program randomized trial. Ann. Intern. Med. 142 (2005), 611–619.
-
(2005)
Ann. Intern. Med.
, vol.142
, pp. 611-619
-
-
Orchard, T.J.1
Temprosa, M.2
Goldberg, R.3
Haffner, S.4
Ratner, R.5
Marcovina, S.6
Fowler, S.7
-
152
-
-
84962079683
-
Cellular senescence in type 2 diabetes: a therapeutic opportunity
-
Palmer, A.K., Tchkonia, T., LeBrasseur, N.K., Chini, E.N., Xu, M., Kirkland, J.L., Cellular senescence in type 2 diabetes: a therapeutic opportunity. Diabetes 64 (2015), 2289–2298.
-
(2015)
Diabetes
, vol.64
, pp. 2289-2298
-
-
Palmer, A.K.1
Tchkonia, T.2
LeBrasseur, N.K.3
Chini, E.N.4
Xu, M.5
Kirkland, J.L.6
-
153
-
-
78649719816
-
Early life growth hormone treatment shortens longevity and decreases cellular stress resistance in long-lived mutant mice
-
Panici, J.A., Harper, J.M., Miller, R.A., Bartke, A., Spong, A., Masternak, M.M., Early life growth hormone treatment shortens longevity and decreases cellular stress resistance in long-lived mutant mice. FASEB J. 24 (2010), 5073–5079.
-
(2010)
FASEB J.
, vol.24
, pp. 5073-5079
-
-
Panici, J.A.1
Harper, J.M.2
Miller, R.A.3
Bartke, A.4
Spong, A.5
Masternak, M.M.6
-
154
-
-
84864283300
-
Muscles, exercise and obesity: skeletal muscle as a secretory organ
-
Pedersen, B.K., Febbraio, M.A., Muscles, exercise and obesity: skeletal muscle as a secretory organ. Nat. Rev. Endocrinol. 8 (2012), 457–465.
-
(2012)
Nat. Rev. Endocrinol.
, vol.8
, pp. 457-465
-
-
Pedersen, B.K.1
Febbraio, M.A.2
-
155
-
-
33645096520
-
Evidence for prescribing exercise as therapy in chronic disease
-
Pedersen, B.K., Saltin, B., Evidence for prescribing exercise as therapy in chronic disease. Scand. J. Med. Sci. Sports 16:Suppl. 1 (2006), 3–63.
-
(2006)
Scand. J. Med. Sci. Sports
, vol.16
, pp. 3-63
-
-
Pedersen, B.K.1
Saltin, B.2
-
156
-
-
84866548765
-
Exercise speeds cutaneous wound healing in high-fat diet-induced obese mice
-
Pence, B.D., DiPietro, L.A., Woods, J.A., Exercise speeds cutaneous wound healing in high-fat diet-induced obese mice. Med. Sci. Sports Exerc. 44 (2012), 1846–1854.
-
(2012)
Med. Sci. Sports Exerc.
, vol.44
, pp. 1846-1854
-
-
Pence, B.D.1
DiPietro, L.A.2
Woods, J.A.3
-
158
-
-
78851472160
-
Resveratrol in cardiovascular health and disease
-
Petrovski, G., Gurusamy, N., Das, D.K., Resveratrol in cardiovascular health and disease. Ann. N. Y. Acad. Sci. 1215 (2011), 22–33.
-
(2011)
Ann. N. Y. Acad. Sci.
, vol.1215
, pp. 22-33
-
-
Petrovski, G.1
Gurusamy, N.2
Das, D.K.3
-
159
-
-
84959357498
-
Frailty, inflammation, and mortality among persons aging with HIV infection and injection drug use
-
Piggott, D.A., Varadhan, R., Mehta, S.H., Brown, T.T., Li, H., Walston, J.D., Leng, S.X., Kirk, G.D., Frailty, inflammation, and mortality among persons aging with HIV infection and injection drug use. J. Gerontol. A Biol. Sci. Med. Sci. 70 (2015), 1542–1547.
-
(2015)
J. Gerontol. A Biol. Sci. Med. Sci.
, vol.70
, pp. 1542-1547
-
-
Piggott, D.A.1
Varadhan, R.2
Mehta, S.H.3
Brown, T.T.4
Li, H.5
Walston, J.D.6
Leng, S.X.7
Kirk, G.D.8
-
160
-
-
0033679675
-
Transcriptional regulation of gene expression in human skeletal muscle during recovery from exercise
-
Pilegaard, H., Ordway, G.A., Saltin, B., Neufer, P.D., Transcriptional regulation of gene expression in human skeletal muscle during recovery from exercise. Am. J. Physiol. Endocrinol. Metab. 279 (2000), E806–E814.
-
(2000)
Am. J. Physiol. Endocrinol. Metab.
, vol.279
, pp. E806-E814
-
-
Pilegaard, H.1
Ordway, G.A.2
Saltin, B.3
Neufer, P.D.4
-
161
-
-
84896855902
-
Resveratrol: therapeutic potential for improving cardiometabolic health
-
Pollack, R.M., Crandall, J.P., Resveratrol: therapeutic potential for improving cardiometabolic health. Am. J. Hypertens. 26 (2013), 1260–1268.
-
(2013)
Am. J. Hypertens.
, vol.26
, pp. 1260-1268
-
-
Pollack, R.M.1
Crandall, J.P.2
-
162
-
-
84948799622
-
Association of habitual dietary resveratrol exposure with the development of frailty in older age: the Invecchiare in chianti study
-
Rabassa, M., Zamora-Ros, R., Urpi-Sarda, M., Bandinelli, S., Ferrucci, L., Andres-Lacueva, C., Cherubini, A., Association of habitual dietary resveratrol exposure with the development of frailty in older age: the Invecchiare in chianti study. Am. J. Clin. Nutr. 102 (2015), 1534–1542.
-
(2015)
Am. J. Clin. Nutr.
, vol.102
, pp. 1534-1542
-
-
Rabassa, M.1
Zamora-Ros, R.2
Urpi-Sarda, M.3
Bandinelli, S.4
Ferrucci, L.5
Andres-Lacueva, C.6
Cherubini, A.7
-
163
-
-
0036452555
-
Exercise training decreases DNA damage and increases DNA repair and resistance against oxidative stress of proteins in aged rat skeletal muscle
-
Radak, Z., Naito, H., Kaneko, T., Tahara, S., Nakamoto, H., Takahashi, R., Cardozo-Pelaez, F., Goto, S., Exercise training decreases DNA damage and increases DNA repair and resistance against oxidative stress of proteins in aged rat skeletal muscle. Pflugers Arch. 445 (2002), 273–278.
-
(2002)
Pflugers Arch.
, vol.445
, pp. 273-278
-
-
Radak, Z.1
Naito, H.2
Kaneko, T.3
Tahara, S.4
Nakamoto, H.5
Takahashi, R.6
Cardozo-Pelaez, F.7
Goto, S.8
-
164
-
-
34147111884
-
8-Oxoguanosine and uracil repair of nuclear and mitochondrial DNA in red and white skeletal muscle of exercise-trained old rats
-
Radak, Z., Kumagai, S., Nakamoto, H., Goto, S., 8-Oxoguanosine and uracil repair of nuclear and mitochondrial DNA in red and white skeletal muscle of exercise-trained old rats. J. Appl. Physiol. (1985) 102 (2007), 1696–1701.
-
(2007)
J. Appl. Physiol. (1985)
, vol.102
, pp. 1696-1701
-
-
Radak, Z.1
Kumagai, S.2
Nakamoto, H.3
Goto, S.4
-
165
-
-
37749053882
-
Exercise, oxidative stress and hormesis
-
Radak, Z., Chung, H.Y., Koltai, E., Taylor, A.W., Goto, S., Exercise, oxidative stress and hormesis. Ageing Res. Rev. 7 (2008), 34–42.
-
(2008)
Ageing Res. Rev.
, vol.7
, pp. 34-42
-
-
Radak, Z.1
Chung, H.Y.2
Koltai, E.3
Taylor, A.W.4
Goto, S.5
-
166
-
-
84964579558
-
Wound complications and surgical events in de novo heart transplant patients treated with everolimus: post-hoc analysis of the SCHEDULE trial
-
Rashidi, M., Esmaily, S., Fiane, A.E., Gude, E., Tønseth, K.A., Ueland, T., Gustafsson, F., Eiskjaer, H., Radegran, G., Dellgren, G., Wound complications and surgical events in de novo heart transplant patients treated with everolimus: post-hoc analysis of the SCHEDULE trial. Int. J. Cardiol. 210 (2016), 80–84.
-
(2016)
Int. J. Cardiol.
, vol.210
, pp. 80-84
-
-
Rashidi, M.1
Esmaily, S.2
Fiane, A.E.3
Gude, E.4
Tønseth, K.A.5
Ueland, T.6
Gustafsson, F.7
Eiskjaer, H.8
Radegran, G.9
Dellgren, G.10
-
167
-
-
84943239001
-
A 2-year randomized controlled trial of human caloric restriction: feasibility and effects on predictors of health span and longevity
-
Ravussin, E., Redman, L.M., Rochon, J., Das, S.K., Fontana, L., Kraus, W.E., Romashkan, S., Williamson, D.A., Meydani, S.N., Villareal, D.T., Smith, S.R., Stein, R.I., Scott, T.M., Stewart, T.M., Saltzman, E., Klein, S., Bhapkar, M., Martin, C.K., Gilhooly, C.H., Holloszy, J.O., Hadley, E.C., Roberts, S.B., A 2-year randomized controlled trial of human caloric restriction: feasibility and effects on predictors of health span and longevity. J. Gerontol. A Biol. Sci. Med. Sci. 70 (2015), 1097–1104.
-
(2015)
J. Gerontol. A Biol. Sci. Med. Sci.
, vol.70
, pp. 1097-1104
-
-
Ravussin, E.1
Redman, L.M.2
Rochon, J.3
Das, S.K.4
Fontana, L.5
Kraus, W.E.6
Romashkan, S.7
Williamson, D.A.8
Meydani, S.N.9
Villareal, D.T.10
Smith, S.R.11
Stein, R.I.12
Scott, T.M.13
Stewart, T.M.14
Saltzman, E.15
Klein, S.16
Bhapkar, M.17
Martin, C.K.18
Gilhooly, C.H.19
Holloszy, J.O.20
Hadley, E.C.21
Roberts, S.B.22
more..
-
168
-
-
0028968016
-
Effects of aging and caloric restriction on extracellular matrix biosynthesis in a model of injury repair in rats
-
Reiser, K., McGee, C., Rucker, R., McDonald, R., Effects of aging and caloric restriction on extracellular matrix biosynthesis in a model of injury repair in rats. J. Gerontol. A Biol. Sci. Med. Sci. 50A (1995), B40–B47.
-
(1995)
J. Gerontol. A Biol. Sci. Med. Sci.
, vol.50A
, pp. B40-B47
-
-
Reiser, K.1
McGee, C.2
Rucker, R.3
McDonald, R.4
-
169
-
-
84883448345
-
Benefits of short-term dietary restriction in mammals
-
Robertson, L.T., Mitchell, J.R., Benefits of short-term dietary restriction in mammals. Exp. Gerontol. 48 (2013), 1043–1048.
-
(2013)
Exp. Gerontol.
, vol.48
, pp. 1043-1048
-
-
Robertson, L.T.1
Mitchell, J.R.2
-
170
-
-
84935114351
-
Protein and calorie restriction contribute additively to protection from renal ischemia reperfusion injury partly via Leptin reduction in male mice
-
Robertson, L.T., Trevino-Villarreal, J.H., Mejia, P., Grondin, Y., Harputlugil, E., Hine, C., Vargas, D., Zheng, H., Ozaki, C.K., Kristal, B.S., Simpson, S.J., Mitchell, J.R., Protein and calorie restriction contribute additively to protection from renal ischemia reperfusion injury partly via Leptin reduction in male mice. J. Nutr. 145 (2015), 1717–1727.
-
(2015)
J. Nutr.
, vol.145
, pp. 1717-1727
-
-
Robertson, L.T.1
Trevino-Villarreal, J.H.2
Mejia, P.3
Grondin, Y.4
Harputlugil, E.5
Hine, C.6
Vargas, D.7
Zheng, H.8
Ozaki, C.K.9
Kristal, B.S.10
Simpson, S.J.11
Mitchell, J.R.12
-
171
-
-
84860461929
-
TOR signaling and rapamycin influence longevity by regulating SKN-1/Nrf and DAF-16/FoxO
-
Robida-Stubbs, S., Glover-Cutter, K., Lamming, D.W., Mizunuma, M., Narasimhan, S.D., Neumann-Haefelin, E., Sabatini, D.M., Blackwell, T.K., TOR signaling and rapamycin influence longevity by regulating SKN-1/Nrf and DAF-16/FoxO. Cell Metab. 15 (2012), 713–724.
-
(2012)
Cell Metab.
, vol.15
, pp. 713-724
-
-
Robida-Stubbs, S.1
Glover-Cutter, K.2
Lamming, D.W.3
Mizunuma, M.4
Narasimhan, S.D.5
Neumann-Haefelin, E.6
Sabatini, D.M.7
Blackwell, T.K.8
-
172
-
-
50049127614
-
Sarcopenia: its assessment, etiology, pathogenesis, consequences and future perspectives
-
Rolland, Y., Czerwinski, S., Abellan Van Kan, G., Morley, J.E., Cesari, M., Onder, G., Woo, J., Baumgartner, R., Pillard, F., Boirie, Y., Chumlea, W.M., Vellas, B., Sarcopenia: its assessment, etiology, pathogenesis, consequences and future perspectives. J. Nutr. Health Aging 12 (2008), 433–450.
-
(2008)
J. Nutr. Health Aging
, vol.12
, pp. 433-450
-
-
Rolland, Y.1
Czerwinski, S.2
Abellan Van Kan, G.3
Morley, J.E.4
Cesari, M.5
Onder, G.6
Woo, J.7
Baumgartner, R.8
Pillard, F.9
Boirie, Y.10
Chumlea, W.M.11
Vellas, B.12
-
173
-
-
55549130288
-
Bone healing in rats submitted to weight-bearing and non-weight-bearing exercises
-
Rueff-Barroso, C.R., Milagres, D., do Valle, J., Casimiro-Lopes, G., Nogueira-Neto, J.F., Zanier, J.F., Porto, L.C., Bone healing in rats submitted to weight-bearing and non-weight-bearing exercises. Med. Sci. Monit. 14 (2008), BR231–BR236.
-
(2008)
Med. Sci. Monit.
, vol.14
, pp. BR231-BR236
-
-
Rueff-Barroso, C.R.1
Milagres, D.2
do Valle, J.3
Casimiro-Lopes, G.4
Nogueira-Neto, J.F.5
Zanier, J.F.6
Porto, L.C.7
-
174
-
-
77953642929
-
Fasting and cancer treatment in humans: a case series report
-
Safdie, F.M., Dorff, T., Quinn, D., Fontana, L., Wei, M., Lee, C., Cohen, P., Longo, V.D., Fasting and cancer treatment in humans: a case series report. Aging (Albany NY) 1 (2009), 988–1007.
-
(2009)
Aging (Albany NY)
, vol.1
, pp. 988-1007
-
-
Safdie, F.M.1
Dorff, T.2
Quinn, D.3
Fontana, L.4
Wei, M.5
Lee, C.6
Cohen, P.7
Longo, V.D.8
-
175
-
-
84866274799
-
Fasting enhances the response of glioma to chemo- and radiotherapy
-
e44603
-
Safdie, F., Brandhorst, S., Wei, M., Wang, W., Lee, C., Hwang, S., Conti, P.S., Chen, T.C., Longo, V.D., Fasting enhances the response of glioma to chemo- and radiotherapy. PLoS One, 7, 2012, e44603.
-
(2012)
PLoS One
, vol.7
-
-
Safdie, F.1
Brandhorst, S.2
Wei, M.3
Wang, W.4
Lee, C.5
Hwang, S.6
Conti, P.S.7
Chen, T.C.8
Longo, V.D.9
-
176
-
-
21044450084
-
Fibroblast cell lines from young adult mice of long-lived mutant strains are resistant to multiple forms of stress
-
Salmon, A.B., Murakami, S., Bartke, A., Kopchick, J., Yasumura, K., Miller, R.A., Fibroblast cell lines from young adult mice of long-lived mutant strains are resistant to multiple forms of stress. Am. J. Physiol. Endocrinol. Metab. 289 (2005), E23–E29.
-
(2005)
Am. J. Physiol. Endocrinol. Metab.
, vol.289
, pp. E23-E29
-
-
Salmon, A.B.1
Murakami, S.2
Bartke, A.3
Kopchick, J.4
Yasumura, K.5
Miller, R.A.6
-
177
-
-
80755169461
-
Domains of physical activity and all-cause mortality: systematic review and dose-response meta-analysis of cohort studies
-
Samitz, G., Egger, M., Zwahlen, M., Domains of physical activity and all-cause mortality: systematic review and dose-response meta-analysis of cohort studies. Int. J. Epidemiol. 40 (2011), 1382–1400.
-
(2011)
Int. J. Epidemiol.
, vol.40
, pp. 1382-1400
-
-
Samitz, G.1
Egger, M.2
Zwahlen, M.3
-
178
-
-
85070847918
-
Rapamycin increases mortality in db/db mice, a mouse model of type 2 diabetes
-
pii: glv170. (Epub ahead of print)
-
Sataranatarajan, K., Ikeno, Y., Bokov, A., Feliers, D., Yalamanchili, H., Lee, H.J., Mariappan, M.M., Tabatabai-Mir, H., Diaz, V., Prasad, S., Javors, M.A., Ghosh Choudhury, G., Hubbard, G.B., Barnes, J.L., Richardson, A., Kasinath, B.S., Rapamycin increases mortality in db/db mice, a mouse model of type 2 diabetes. J. Gerontol. A Biol. Sci. Med. Sci., 2015 pii: glv170. (Epub ahead of print).
-
(2015)
J. Gerontol. A Biol. Sci. Med. Sci.
-
-
Sataranatarajan, K.1
Ikeno, Y.2
Bokov, A.3
Feliers, D.4
Yalamanchili, H.5
Lee, H.J.6
Mariappan, M.M.7
Tabatabai-Mir, H.8
Diaz, V.9
Prasad, S.10
Javors, M.A.11
Ghosh Choudhury, G.12
Hubbard, G.B.13
Barnes, J.L.14
Richardson, A.15
Kasinath, B.S.16
-
179
-
-
84969872759
-
Exercise Prevents Diet-Induced Cellular Senescence in Adipose Tissue
-
Schafer, M.J., White, T.A., Evans, G., Tonne, J.M., Verzosa, G.C., Stout, M.B., Mazula, D.L., Palmer, A.K., Baker, D.J., Jensen, M.D., Torbenson, M.S., Miller, J.D., Ikeda, Y., Tchkonia, T., Exercise Prevents Diet-Induced Cellular Senescence in Adipose Tissue. Diabetes 65:6 (2016), 1606–1615, 10.2337/db15-0291.
-
(2016)
Diabetes
, vol.65
, Issue.6
, pp. 1606-1615
-
-
Schafer, M.J.1
White, T.A.2
Evans, G.3
Tonne, J.M.4
Verzosa, G.C.5
Stout, M.B.6
Mazula, D.L.7
Palmer, A.K.8
Baker, D.J.9
Jensen, M.D.10
Torbenson, M.S.11
Miller, J.D.12
Ikeda, Y.13
Tchkonia, T.14
-
180
-
-
50849100719
-
Delayed and accelerated aging share common longevity assurance mechanisms
-
e1000161
-
Schumacher, B., van der Pluijm, I., Moorhouse, M.J., Kosteas, T., Robinson, A.R., Suh, Y., Breit, T.M., van Steeg, H., Niedernhofer, L.J., van Ijcken, W., Bartke, A., Spindler, S.R., Hoeijmakers, J.H., van der Horst, G.T., Garinis, G.A., Delayed and accelerated aging share common longevity assurance mechanisms. PLoS Genet., 4, 2008, e1000161.
-
(2008)
PLoS Genet.
, vol.4
-
-
Schumacher, B.1
van der Pluijm, I.2
Moorhouse, M.J.3
Kosteas, T.4
Robinson, A.R.5
Suh, Y.6
Breit, T.M.7
van Steeg, H.8
Niedernhofer, L.J.9
van Ijcken, W.10
Bartke, A.11
Spindler, S.R.12
Hoeijmakers, J.H.13
van der Horst, G.T.14
Garinis, G.A.15
-
181
-
-
84925356673
-
Metformin for primary colorectal cancer prevention in patients with diabetes: a case-control study in a US population
-
Sehdev, A., Shih, Y.C., Vekhter, B., Bissonnette, M.B., Olopade, O.I., Polite, B.N., Metformin for primary colorectal cancer prevention in patients with diabetes: a case-control study in a US population. Cancer 121 (2015), 1071–1078.
-
(2015)
Cancer
, vol.121
, pp. 1071-1078
-
-
Sehdev, A.1
Shih, Y.C.2
Vekhter, B.3
Bissonnette, M.B.4
Olopade, O.I.5
Polite, B.N.6
-
182
-
-
84964917260
-
Resveratrol enhances HBV replication through activating Sirt1-PGC-1alpha-PPARalpha pathway
-
Shi, Y., Li, Y., Huang, C., Ying, L., Xue, J., Wu, H., Chen, Z., Yang, Z., Resveratrol enhances HBV replication through activating Sirt1-PGC-1alpha-PPARalpha pathway. Sci. Rep., 6, 2016, 24744.
-
(2016)
Sci. Rep.
, vol.6
, pp. 24744
-
-
Shi, Y.1
Li, Y.2
Huang, C.3
Ying, L.4
Xue, J.5
Wu, H.6
Chen, Z.7
Yang, Z.8
-
183
-
-
84902436230
-
Metformin attenuates palmitate-induced endoplasmic reticulum stress, serine phosphorylation of IRS-1 and apoptosis in rat insulinoma cells
-
e97868
-
Simon-Szabo, L., Kokas, M., Mandl, J., Keri, G., Csala, M., Metformin attenuates palmitate-induced endoplasmic reticulum stress, serine phosphorylation of IRS-1 and apoptosis in rat insulinoma cells. PLoS One, 9, 2014, e97868.
-
(2014)
PLoS One
, vol.9
-
-
Simon-Szabo, L.1
Kokas, M.2
Mandl, J.3
Keri, G.4
Csala, M.5
-
184
-
-
84860914897
-
Exercise and the aging immune system
-
Simpson, R.J., Lowder, T.W., Spielmann, G., Bigley, A.B., LaVoy, E.C., Kunz, H., Exercise and the aging immune system. Ageing Res. Rev. 11 (2012), 404–420.
-
(2012)
Ageing Res. Rev.
, vol.11
, pp. 404-420
-
-
Simpson, R.J.1
Lowder, T.W.2
Spielmann, G.3
Bigley, A.B.4
LaVoy, E.C.5
Kunz, H.6
-
185
-
-
84878849527
-
A systematic review of pre-surgical exercise intervention studies with cancer patients
-
Singh, F., Newton, R.U., Galvao, D.A., Spry, N., Baker, M.K., A systematic review of pre-surgical exercise intervention studies with cancer patients. Surg. Oncol. 22 (2013), 92–104.
-
(2013)
Surg. Oncol.
, vol.22
, pp. 92-104
-
-
Singh, F.1
Newton, R.U.2
Galvao, D.A.3
Spry, N.4
Baker, M.K.5
-
186
-
-
84911883683
-
Metformin as adjunct antituberculosis therapy
-
263ra159
-
Singhal, A., Jie, L., Kumar, P., Hong, G.S., Leow, M.K., Paleja, B., Tsenova, L., Kurepina, N., Chen, J., Zolezzi, F., Kreiswirth, B., Poidinger, M., Chee, C., Kaplan, G., Wang, Y.T., De Libero, G., Metformin as adjunct antituberculosis therapy. Sci. Transl. Med., 6, 2014, 263ra159.
-
(2014)
Sci. Transl. Med.
, vol.6
-
-
Singhal, A.1
Jie, L.2
Kumar, P.3
Hong, G.S.4
Leow, M.K.5
Paleja, B.6
Tsenova, L.7
Kurepina, N.8
Chen, J.9
Zolezzi, F.10
Kreiswirth, B.11
Poidinger, M.12
Chee, C.13
Kaplan, G.14
Wang, Y.T.15
De Libero, G.16
-
187
-
-
77951908829
-
Metformin supplementation and life span in Fischer-344 rats
-
Smith, D.L. Jr., Elam, C.F. Jr., Mattison, J.A., Lane, M.A., Roth, G.S., Ingram, D.K., Allison, D.B., Metformin supplementation and life span in Fischer-344 rats. J. Gerontol. A Biol. Sci. Med. Sci. 65 (2010), 468–474.
-
(2010)
J. Gerontol. A Biol. Sci. Med. Sci.
, vol.65
, pp. 468-474
-
-
Smith, D.L.1
Elam, C.F.2
Mattison, J.A.3
Lane, M.A.4
Roth, G.S.5
Ingram, D.K.6
Allison, D.B.7
-
188
-
-
0026621437
-
Bone mineral density, muscle strength, and recreational exercise in men
-
Snow-Harter, C., Whalen, R., Myburgh, K., Arnaud, S., Marcus, R., Bone mineral density, muscle strength, and recreational exercise in men. J. Bone Miner. Res. 7 (1992), 1291–1296.
-
(1992)
J. Bone Miner. Res.
, vol.7
, pp. 1291-1296
-
-
Snow-Harter, C.1
Whalen, R.2
Myburgh, K.3
Arnaud, S.4
Marcus, R.5
-
189
-
-
84930637693
-
Effects of combined physical exercise training on DNA damage and repair capacity: role of oxidative stress changes
-
Soares, J.P., Silva, A.M., Oliveira, M.M., Peixoto, F., Gaivao, I., Mota, M.P., Effects of combined physical exercise training on DNA damage and repair capacity: role of oxidative stress changes. Age (Dordr.), 37, 2015, 9799.
-
(2015)
Age (Dordr.)
, vol.37
, pp. 9799
-
-
Soares, J.P.1
Silva, A.M.2
Oliveira, M.M.3
Peixoto, F.4
Gaivao, I.5
Mota, M.P.6
-
190
-
-
84895765028
-
The ratio of macronutrients, not caloric intake, dictates cardiometabolic health, aging, and longevity in ad libitum-fed mice
-
Solon-Biet, S.M., McMahon, A.C., Ballard, J.W., Ruohonen, K., Wu, L.E., Cogger, V.C., Warren, A., Huang, X., Pichaud, N., Melvin, R.G., Gokarn, R., Khalil, M., Turner, N., Cooney, G.J., Sinclair, D.A., Raubenheimer, D., Le Couteur, D.G., Simpson, S.J., The ratio of macronutrients, not caloric intake, dictates cardiometabolic health, aging, and longevity in ad libitum-fed mice. Cell Metab. 19 (2014), 418–430.
-
(2014)
Cell Metab.
, vol.19
, pp. 418-430
-
-
Solon-Biet, S.M.1
McMahon, A.C.2
Ballard, J.W.3
Ruohonen, K.4
Wu, L.E.5
Cogger, V.C.6
Warren, A.7
Huang, X.8
Pichaud, N.9
Melvin, R.G.10
Gokarn, R.11
Khalil, M.12
Turner, N.13
Cooney, G.J.14
Sinclair, D.A.15
Raubenheimer, D.16
Le Couteur, D.G.17
Simpson, S.J.18
-
192
-
-
34247153540
-
Starving for life: what animal studies can and cannot tell us about the use of caloric restriction to prolong human lifespan
-
Speakman, J.R., Hambly, C., Starving for life: what animal studies can and cannot tell us about the use of caloric restriction to prolong human lifespan. J. Nutr. 137 (2007), 1078–1086.
-
(2007)
J. Nutr.
, vol.137
, pp. 1078-1086
-
-
Speakman, J.R.1
Hambly, C.2
-
193
-
-
84870571061
-
Brain volumetric and microstructural correlates of executive and motor performance in aged rhesus monkeys
-
Sridharan, A., Willette, A.A., Bendlin, B.B., Alexander, A.L., Coe, C.L., Voytko, M.L., Colman, R.J., Kemnitz, J.W., Weindruch, R.H., Johnson, S.C., Brain volumetric and microstructural correlates of executive and motor performance in aged rhesus monkeys. Front. Aging Neurosci., 4, 2012, 31.
-
(2012)
Front. Aging Neurosci.
, vol.4
, pp. 31
-
-
Sridharan, A.1
Willette, A.A.2
Bendlin, B.B.3
Alexander, A.L.4
Coe, C.L.5
Voytko, M.L.6
Colman, R.J.7
Kemnitz, J.W.8
Weindruch, R.H.9
Johnson, S.C.10
-
194
-
-
84922388953
-
Risk of developing multimorbidity across all ages in an historical cohort study: differences by sex and ethnicity
-
e006413
-
St Sauver, J.L., Boyd, C.M., Grossardt, B.R., Bobo, W.V., Finney Rutten, L.J., Roger, V.L., Ebbert, J.O., Therneau, T.M., Yawn, B.P., Rocca, W.A., Risk of developing multimorbidity across all ages in an historical cohort study: differences by sex and ethnicity. BMJ Open, 5, 2015, e006413.
-
(2015)
BMJ Open
, vol.5
-
-
St Sauver, J.L.1
Boyd, C.M.2
Grossardt, B.R.3
Bobo, W.V.4
Finney Rutten, L.J.5
Roger, V.L.6
Ebbert, J.O.7
Therneau, T.M.8
Yawn, B.P.9
Rocca, W.A.10
-
195
-
-
84871876229
-
Evaluation of resveratrol, green tea extract, curcumin, oxaloacetic acid, and medium-chain triglyceride oil on life span of genetically heterogeneous mice
-
Strong, R., Miller, R.A., Astle, C.M., Baur, J.A., de Cabo, R., Fernandez, E., Guo, W., Javors, M., Kirkland, J.L., Nelson, J.F., Sinclair, D.A., Teter, B., Williams, D., Zaveri, N., Nadon, N.L., Harrison, D.E., Evaluation of resveratrol, green tea extract, curcumin, oxaloacetic acid, and medium-chain triglyceride oil on life span of genetically heterogeneous mice. J. Gerontol. A Biol. Sci. Med. Sci. 68 (2013), 6–16.
-
(2013)
J. Gerontol. A Biol. Sci. Med. Sci.
, vol.68
, pp. 6-16
-
-
Strong, R.1
Miller, R.A.2
Astle, C.M.3
Baur, J.A.4
de Cabo, R.5
Fernandez, E.6
Guo, W.7
Javors, M.8
Kirkland, J.L.9
Nelson, J.F.10
Sinclair, D.A.11
Teter, B.12
Williams, D.13
Zaveri, N.14
Nadon, N.L.15
Harrison, D.E.16
-
196
-
-
84933523001
-
Relationship between metformin and frailty syndrome in elderly people with type 2 diabetes
-
Sumantri, S., Setiati, S., Purnamasari, D., Dewiasty, E., Relationship between metformin and frailty syndrome in elderly people with type 2 diabetes. Acta Med. Indones. 46 (2014), 183–188.
-
(2014)
Acta Med. Indones.
, vol.46
, pp. 183-188
-
-
Sumantri, S.1
Setiati, S.2
Purnamasari, D.3
Dewiasty, E.4
-
197
-
-
67649660052
-
Life-span extension in mice by preweaning food restriction and by methionine restriction in middle age
-
Sun, L., Sadighi Akha, A.A., Miller, R.A., Harper, J.M., Life-span extension in mice by preweaning food restriction and by methionine restriction in middle age. J. Gerontol. A Biol. Sci. Med. Sci. 64 (2009), 711–722.
-
(2009)
J. Gerontol. A Biol. Sci. Med. Sci.
, vol.64
, pp. 711-722
-
-
Sun, L.1
Sadighi Akha, A.A.2
Miller, R.A.3
Harper, J.M.4
-
198
-
-
84874603171
-
Cellular senescence and the senescent secretory phenotype: therapeutic opportunities
-
Tchkonia, T., Zhu, Y., van Deursen, J., Campisi, J., Kirkland, J.L., Cellular senescence and the senescent secretory phenotype: therapeutic opportunities. J. Clin. Invest. 123 (2013), 966–972.
-
(2013)
J. Clin. Invest.
, vol.123
, pp. 966-972
-
-
Tchkonia, T.1
Zhu, Y.2
van Deursen, J.3
Campisi, J.4
Kirkland, J.L.5
-
199
-
-
84860196977
-
Genetics, life span, health span, and the aging process in Caenorhabditis elegans
-
Tissenbaum, H.A., Genetics, life span, health span, and the aging process in Caenorhabditis elegans. J. Gerontol. A Biol. Sci. Med. Sci. 67 (2012), 503–510.
-
(2012)
J. Gerontol. A Biol. Sci. Med. Sci.
, vol.67
, pp. 503-510
-
-
Tissenbaum, H.A.1
-
200
-
-
84927912561
-
Aging exacerbates hypertension-induced cerebral microhemorrhages in mice: role of resveratrol treatment in vasoprotection
-
Toth, P., Tarantini, S., Springo, Z., Tucsek, Z., Gautam, T., Giles, C.B., Wren, J.D., Koller, A., Sonntag, W.E., Csiszar, A., Ungvari, Z., Aging exacerbates hypertension-induced cerebral microhemorrhages in mice: role of resveratrol treatment in vasoprotection. Aging Cell 14 (2015), 400–408.
-
(2015)
Aging Cell
, vol.14
, pp. 400-408
-
-
Toth, P.1
Tarantini, S.2
Springo, Z.3
Tucsek, Z.4
Gautam, T.5
Giles, C.B.6
Wren, J.D.7
Koller, A.8
Sonntag, W.E.9
Csiszar, A.10
Ungvari, Z.11
-
201
-
-
34250842528
-
Resveratrol increases vascular oxidative stress resistance
-
Ungvari, Z., Orosz, Z., Rivera, A., Labinskyy, N., Xiangmin, Z., Olson, S., Podlutsky, A., Csiszar, A., Resveratrol increases vascular oxidative stress resistance. Am. J. Physiol. Heart Circ. Physiol. 292 (2007), H2417–H2424.
-
(2007)
Am. J. Physiol. Heart Circ. Physiol.
, vol.292
, pp. H2417-H2424
-
-
Ungvari, Z.1
Orosz, Z.2
Rivera, A.3
Labinskyy, N.4
Xiangmin, Z.5
Olson, S.6
Podlutsky, A.7
Csiszar, A.8
-
202
-
-
84901288438
-
The role of senescent cells in ageing
-
van Deursen, J.M., The role of senescent cells in ageing. Nature 509 (2014), 439–446.
-
(2014)
Nature
, vol.509
, pp. 439-446
-
-
van Deursen, J.M.1
-
203
-
-
56949092215
-
Stimulus-response paradigm for characterizing the loss of resilience in homeostatic regulation associated with frailty
-
Varadhan, R., Seplaki, C.L., Xue, Q.L., Bandeen-Roche, K., Fried, L.P., Stimulus-response paradigm for characterizing the loss of resilience in homeostatic regulation associated with frailty. Mech. Ageing Dev. 129 (2008), 666–670.
-
(2008)
Mech. Ageing Dev.
, vol.129
, pp. 666-670
-
-
Varadhan, R.1
Seplaki, C.L.2
Xue, Q.L.3
Bandeen-Roche, K.4
Fried, L.P.5
-
204
-
-
9644270414
-
Hippocampal BDNF mediates the efficacy of exercise on synaptic plasticity and cognition
-
Vaynman, S., Ying, Z., Gomez-Pinilla, F., Hippocampal BDNF mediates the efficacy of exercise on synaptic plasticity and cognition. Eur. J. Neurosci. 20 (2004), 2580–2590.
-
(2004)
Eur. J. Neurosci.
, vol.20
, pp. 2580-2590
-
-
Vaynman, S.1
Ying, Z.2
Gomez-Pinilla, F.3
-
205
-
-
84957442302
-
Effect of two-year caloric restriction on bone metabolism and bone mineral density in non-obese younger adults: a randomized clinical trial
-
Villareal, D.T., Fontana, L., Das, S.K., Redman, L., Smith, S.R., Saltzman, E., Bales, C., Rochon, J., Pieper, C., Huang, M., Lewis, M., Schwartz, A.V., Effect of two-year caloric restriction on bone metabolism and bone mineral density in non-obese younger adults: a randomized clinical trial. J. Bone Miner. Res. 31 (2016), 40–51.
-
(2016)
J. Bone Miner. Res.
, vol.31
, pp. 40-51
-
-
Villareal, D.T.1
Fontana, L.2
Das, S.K.3
Redman, L.4
Smith, S.R.5
Saltzman, E.6
Bales, C.7
Rochon, J.8
Pieper, C.9
Huang, M.10
Lewis, M.11
Schwartz, A.V.12
-
206
-
-
78049404627
-
Regulation of muscle atrophy in aging and disease
-
Vinciguerra, M., Musaro, A., Rosenthal, N., Regulation of muscle atrophy in aging and disease. Adv. Exp. Med. Biol. 694 (2010), 211–233.
-
(2010)
Adv. Exp. Med. Biol.
, vol.694
, pp. 211-233
-
-
Vinciguerra, M.1
Musaro, A.2
Rosenthal, N.3
-
207
-
-
84864020954
-
The number of p16INK4a positive cells in human skin reflects biological age
-
Waaijer, M.E., Parish, W.E., Strongitharm, B.H., van Heemst, D., Slagboom, P.E., de Craen, A.J., Sedivy, J.M., Westendorp, R.G., Gunn, D.A., Maier, A.B., The number of p16INK4a positive cells in human skin reflects biological age. Aging Cell 11 (2012), 722–725.
-
(2012)
Aging Cell
, vol.11
, pp. 722-725
-
-
Waaijer, M.E.1
Parish, W.E.2
Strongitharm, B.H.3
van Heemst, D.4
Slagboom, P.E.5
de Craen, A.J.6
Sedivy, J.M.7
Westendorp, R.G.8
Gunn, D.A.9
Maier, A.B.10
-
208
-
-
84937441058
-
Frailty attenuates the impact of metformin on reducing mortality in older adults with type 2 diabetes
-
Wang, C.P., Lorenzo, C., Espinoza, S.E., Frailty attenuates the impact of metformin on reducing mortality in older adults with type 2 diabetes. J. Endocrinol. Diabetes Obes., 2, 2014.
-
(2014)
J. Endocrinol. Diabetes Obes.
, vol.2
-
-
Wang, C.P.1
Lorenzo, C.2
Espinoza, S.E.3
-
209
-
-
79955161098
-
The athlete's heart vs. the failing heart: can signaling explain the two distinct outcomes?
-
Weeks, K.L., McMullen, J.R., The athlete's heart vs. the failing heart: can signaling explain the two distinct outcomes?. Physiology (Bethesda) 26 (2011), 97–105.
-
(2011)
Physiology (Bethesda)
, vol.26
, pp. 97-105
-
-
Weeks, K.L.1
McMullen, J.R.2
-
210
-
-
0026768421
-
Effect of caloric restriction on age-associated cancers
-
Weindruch, R., Effect of caloric restriction on age-associated cancers. Exp. Gerontol. 27 (1992), 575–581.
-
(1992)
Exp. Gerontol.
, vol.27
, pp. 575-581
-
-
Weindruch, R.1
-
211
-
-
0030466371
-
The retardation of aging by caloric restriction: studies in rodents and primates
-
Weindruch, R., The retardation of aging by caloric restriction: studies in rodents and primates. Toxicol. Pathol. 24 (1996), 742–745.
-
(1996)
Toxicol. Pathol.
, vol.24
, pp. 742-745
-
-
Weindruch, R.1
-
212
-
-
73349128101
-
Physical exercise prevents cellular senescence in circulating leukocytes and in the vessel wall
-
Werner, C., Furster, T., Widmann, T., Poss, J., Roggia, C., Hanhoun, M., Scharhag, J., Buchner, N., Meyer, T., Kindermann, W., Haendeler, J., Bohm, M., Laufs, U., Physical exercise prevents cellular senescence in circulating leukocytes and in the vessel wall. Circulation 120 (2009), 2438–2447.
-
(2009)
Circulation
, vol.120
, pp. 2438-2447
-
-
Werner, C.1
Furster, T.2
Widmann, T.3
Poss, J.4
Roggia, C.5
Hanhoun, M.6
Scharhag, J.7
Buchner, N.8
Meyer, T.9
Kindermann, W.10
Haendeler, J.11
Bohm, M.12
Laufs, U.13
-
213
-
-
56949090811
-
New light on an age-old issue
-
Whitson, H.E., Pieper, C.F., Cohen, H.J., New light on an age-old issue. Mech. Ageing Dev. 129 (2008), 673–674.
-
(2008)
Mech. Ageing Dev.
, vol.129
, pp. 673-674
-
-
Whitson, H.E.1
Pieper, C.F.2
Cohen, H.J.3
-
214
-
-
84867578963
-
Sedentary time in adults and the association with diabetes, cardiovascular disease and death: systematic review and meta-analysis
-
Wilmot, E.G., Edwardson, C.L., Achana, F.A., Davies, M.J., Gorely, T., Gray, L.J., Khunti, K., Yates, T., Biddle, S.J., Sedentary time in adults and the association with diabetes, cardiovascular disease and death: systematic review and meta-analysis. Diabetologia 55 (2012), 2895–2905.
-
(2012)
Diabetologia
, vol.55
, pp. 2895-2905
-
-
Wilmot, E.G.1
Edwardson, C.L.2
Achana, F.A.3
Davies, M.J.4
Gorely, T.5
Gray, L.J.6
Khunti, K.7
Yates, T.8
Biddle, S.J.9
-
215
-
-
84930227319
-
A network flow-based analysis of cognitive Reserve in Normal Ageing and Alzheimer's disease
-
Wook Yoo, S., Han, C.E., Shin, J.S., Won Seo, S., Na, D.L., Kaiser, M., Jeong, Y., Seong, J.K., A network flow-based analysis of cognitive Reserve in Normal Ageing and Alzheimer's disease. Sci. Rep., 5, 2015, 10057.
-
(2015)
Sci. Rep.
, vol.5
, pp. 10057
-
-
Wook Yoo, S.1
Han, C.E.2
Shin, J.S.3
Won Seo, S.4
Na, D.L.5
Kaiser, M.6
Jeong, Y.7
Seong, J.K.8
-
216
-
-
84966397603
-
JAK inhibition alleviates the cellular senescence-associated secretory phenotype and frailty in old age
-
Xu, M., Tchkonia, T., Ding, H., Ogrodnik, M., Lubbers, E.R., Pirtskhalava, T., White, T.A., Johnson, K.O., Stout, M.B., Mezera, V., Giorgadze, N., Jensen, M.D., LeBrasseur, N.K., Kirkland, J.L., JAK inhibition alleviates the cellular senescence-associated secretory phenotype and frailty in old age. Proc. Natl. Acad. Sci. U. S. A. 112 (2015), E6301–E6310.
-
(2015)
Proc. Natl. Acad. Sci. U. S. A.
, vol.112
, pp. E6301-E6310
-
-
Xu, M.1
Tchkonia, T.2
Ding, H.3
Ogrodnik, M.4
Lubbers, E.R.5
Pirtskhalava, T.6
White, T.A.7
Johnson, K.O.8
Stout, M.B.9
Mezera, V.10
Giorgadze, N.11
Jensen, M.D.12
LeBrasseur, N.K.13
Kirkland, J.L.14
-
217
-
-
84892372881
-
Effects of resveratrol on incisional wound healing in rats
-
Yaman, I., Derici, H., Kara, C., Kamer, E., Diniz, G., Ortac, R., Sayin, O., Effects of resveratrol on incisional wound healing in rats. Surg. Today 43 (2013), 1433–1438.
-
(2013)
Surg. Today
, vol.43
, pp. 1433-1438
-
-
Yaman, I.1
Derici, H.2
Kara, C.3
Kamer, E.4
Diniz, G.5
Ortac, R.6
Sayin, O.7
-
218
-
-
70349231092
-
Inhibition of thymic adipogenesis by caloric restriction is coupled with reduction in age-related thymic involution
-
Yang, H., Youm, Y.H., Dixit, V.D., Inhibition of thymic adipogenesis by caloric restriction is coupled with reduction in age-related thymic involution. J. Immunol. 183 (2009), 3040–3052.
-
(2009)
J. Immunol.
, vol.183
, pp. 3040-3052
-
-
Yang, H.1
Youm, Y.H.2
Dixit, V.D.3
-
219
-
-
84881102986
-
Rapamycin doses sufficient to extend lifespan do not compromise muscle mitochondrial content or endurance
-
Ye, L., Widlund, A.L., Sims, C.A., Lamming, D.W., Guan, Y., Davis, J.G., Sabatini, D.M., Harrison, D.E., Vang, O., Baur, J.A., Rapamycin doses sufficient to extend lifespan do not compromise muscle mitochondrial content or endurance. Aging (Albany NY) 5 (2013), 539–550.
-
(2013)
Aging (Albany NY)
, vol.5
, pp. 539-550
-
-
Ye, L.1
Widlund, A.L.2
Sims, C.A.3
Lamming, D.W.4
Guan, Y.5
Davis, J.G.6
Sabatini, D.M.7
Harrison, D.E.8
Vang, O.9
Baur, J.A.10
-
220
-
-
84871445402
-
Resveratrol supplementation does not improve metabolic function in nonobese women with normal glucose tolerance
-
Yoshino, J., Conte, C., Fontana, L., Mittendorfer, B., Imai, S., Schechtman, K.B., Gu, C., Kunz, I., Rossi Fanelli, F., Patterson, B.W., Klein, S., Resveratrol supplementation does not improve metabolic function in nonobese women with normal glucose tolerance. Cell Metab. 16 (2012), 658–664.
-
(2012)
Cell Metab.
, vol.16
, pp. 658-664
-
-
Yoshino, J.1
Conte, C.2
Fontana, L.3
Mittendorfer, B.4
Imai, S.5
Schechtman, K.B.6
Gu, C.7
Kunz, I.8
Rossi Fanelli, F.9
Patterson, B.W.10
Klein, S.11
-
221
-
-
84939443073
-
Modulation of cardiovascular toxicity in Hodgkin lymphoma: potential role and mechanisms of aerobic training
-
Yu, A.F., Jones, L.W., Modulation of cardiovascular toxicity in Hodgkin lymphoma: potential role and mechanisms of aerobic training. Futur. Cardiol. 11 (2015), 441–452.
-
(2015)
Futur. Cardiol.
, vol.11
, pp. 441-452
-
-
Yu, A.F.1
Jones, L.W.2
-
222
-
-
84868008175
-
Dietary intake of resveratrol enhances the adaptive immunity of aged rats
-
Yuan, J., Lu, L., Zhang, Z., Zhang, S., Dietary intake of resveratrol enhances the adaptive immunity of aged rats. Rejuvenation Res. 15 (2012), 507–515.
-
(2012)
Rejuvenation Res.
, vol.15
, pp. 507-515
-
-
Yuan, J.1
Lu, L.2
Zhang, Z.3
Zhang, S.4
-
223
-
-
68149150846
-
Effects of voluntary and forced exercise on plaque deposition, hippocampal volume, and behavior in the Tg2576 mouse model of Alzheimer's disease
-
Yuede, C.M., Zimmerman, S.D., Dong, H., Kling, M.J., Bero, A.W., Holtzman, D.M., Timson, B.F., Csernansky, J.G., Effects of voluntary and forced exercise on plaque deposition, hippocampal volume, and behavior in the Tg2576 mouse model of Alzheimer's disease. Neurobiol. Dis. 35 (2009), 426–432.
-
(2009)
Neurobiol. Dis.
, vol.35
, pp. 426-432
-
-
Yuede, C.M.1
Zimmerman, S.D.2
Dong, H.3
Kling, M.J.4
Bero, A.W.5
Holtzman, D.M.6
Timson, B.F.7
Csernansky, J.G.8
-
224
-
-
84896800569
-
Rapamycin extends life and health in C57BL/6 mice
-
Zhang, Y., Bokov, A., Gelfond, J., Soto, V., Ikeno, Y., Hubbard, G., Diaz, V., Sloane, L., Maslin, K., Treaster, S., Rendon, S., van Remmen, H., Ward, W., Javors, M., Richardson, A., Austad, S.N., Fischer, K., Rapamycin extends life and health in C57BL/6 mice. J. Gerontol. A Biol. Sci. Med. Sci. 69 (2014), 119–130.
-
(2014)
J. Gerontol. A Biol. Sci. Med. Sci.
, vol.69
, pp. 119-130
-
-
Zhang, Y.1
Bokov, A.2
Gelfond, J.3
Soto, V.4
Ikeno, Y.5
Hubbard, G.6
Diaz, V.7
Sloane, L.8
Maslin, K.9
Treaster, S.10
Rendon, S.11
van Remmen, H.12
Ward, W.13
Javors, M.14
Richardson, A.15
Austad, S.N.16
Fischer, K.17
-
225
-
-
0034773404
-
Role of AMP-activated protein kinase in mechanism of metformin action
-
Zhou, G., Myers, R., Li, Y., Chen, Y., Shen, X., Fenyk-Melody, J., Wu, M., Ventre, J., Doebber, T., Fujii, N., Musi, N., Hirshman, M.F., Goodyear, L.J., Moller, D.E., Role of AMP-activated protein kinase in mechanism of metformin action. J. Clin. Invest. 108 (2001), 1167–1174.
-
(2001)
J. Clin. Invest.
, vol.108
, pp. 1167-1174
-
-
Zhou, G.1
Myers, R.2
Li, Y.3
Chen, Y.4
Shen, X.5
Fenyk-Melody, J.6
Wu, M.7
Ventre, J.8
Doebber, T.9
Fujii, N.10
Musi, N.11
Hirshman, M.F.12
Goodyear, L.J.13
Moller, D.E.14
-
226
-
-
84962157654
-
Metformin prevents Cisplatin-induced cognitive impairment and brain damage in mice
-
e0151890
-
Zhou, W., Kavelaars, A., Heijnen, C.J., Metformin prevents Cisplatin-induced cognitive impairment and brain damage in mice. PLoS One, 11, 2016, e0151890.
-
(2016)
PLoS One
, vol.11
-
-
Zhou, W.1
Kavelaars, A.2
Heijnen, C.J.3
-
227
-
-
84928243456
-
The Achilles' heel of senescent cells: from transcriptome to senolytic drugs
-
Zhu, Y., Tchkonia, T., Pirtskhalava, T., Gower, A.C., Ding, H., Giorgadze, N., Palmer, A.K., Ikeno, Y., Hubbard, G.B., Lenburg, M., O'Hara, S.P., LaRusso, N.F., Miller, J.D., Roos, C.M., Verzosa, G.C., LeBrasseur, N.K., Wren, J.D., Farr, J.N., Khosla, S., Stout, M.B., McGowan, S.J., Fuhrmann-Stroissnigg, H., Gurkar, A.U., Zhao, J., Colangelo, D., Dorronsoro, A., Ling, Y.Y., Barghouthy, A.S., Navarro, D.C., Sano, T., Robbins, P.D., Niedernhofer, L.J., Kirkland, J.L., The Achilles' heel of senescent cells: from transcriptome to senolytic drugs. Aging Cell 14 (2015), 644–658.
-
(2015)
Aging Cell
, vol.14
, pp. 644-658
-
-
Zhu, Y.1
Tchkonia, T.2
Pirtskhalava, T.3
Gower, A.C.4
Ding, H.5
Giorgadze, N.6
Palmer, A.K.7
Ikeno, Y.8
Hubbard, G.B.9
Lenburg, M.10
O'Hara, S.P.11
LaRusso, N.F.12
Miller, J.D.13
Roos, C.M.14
Verzosa, G.C.15
LeBrasseur, N.K.16
Wren, J.D.17
Farr, J.N.18
Khosla, S.19
Stout, M.B.20
McGowan, S.J.21
Fuhrmann-Stroissnigg, H.22
Gurkar, A.U.23
Zhao, J.24
Colangelo, D.25
Dorronsoro, A.26
Ling, Y.Y.27
Barghouthy, A.S.28
Navarro, D.C.29
Sano, T.30
Robbins, P.D.31
Niedernhofer, L.J.32
Kirkland, J.L.33
more..
-
228
-
-
84961223640
-
Identification of a novel senolytic agent, Navitoclax, targeting the Bcl-2 family of anti-apoptotic factors
-
Zhu, Y., Tchkonia, T., Fuhrmann-Stroissnigg, H., Dai, H.M., Ling, Y.Y., Stout, M.B., Pirtskhalava, T., Giorgadze, N., Johnson, K.O., Giles, C.B., Wren, J.D., Niedernhofer, L.J., Robbins, P.D., Kirkland, J.L., Identification of a novel senolytic agent, Navitoclax, targeting the Bcl-2 family of anti-apoptotic factors. Aging Cell. 15:3 (2016), 428–435.
-
(2016)
Aging Cell.
, vol.15
, Issue.3
, pp. 428-435
-
-
Zhu, Y.1
Tchkonia, T.2
Fuhrmann-Stroissnigg, H.3
Dai, H.M.4
Ling, Y.Y.5
Stout, M.B.6
Pirtskhalava, T.7
Giorgadze, N.8
Johnson, K.O.9
Giles, C.B.10
Wren, J.D.11
Niedernhofer, L.J.12
Robbins, P.D.13
Kirkland, J.L.14
|