-
1
-
-
33746530366
-
Efficacy of sirolimus compared with azathioprine for reduction of acute renal allograft rejection: A randomised multicentre study
-
Kahan BD, The Rapamune US Study Group. Efficacy of sirolimus compared with azathioprine for reduction of acute renal allograft rejection: a randomised multicentre study. Lancet 2000 356 : 194 202.
-
(2000)
Lancet
, vol.356
, pp. 194-202
-
-
Kahan, B.D.1
Study Us T.Rapamune2
-
2
-
-
0032105481
-
Rapamune (RAPA, rapamycin, sirolimus): Mechanism of action immunosuppressive effect results from blockade of signal transduction and inhibition of cell cycle progression
-
Sehgal SN. Rapamune (RAPA, rapamycin, sirolimus): mechanism of action immunosuppressive effect results from blockade of signal transduction and inhibition of cell cycle progression. Clin Biochem 1998 31 : 335 40.
-
(1998)
Clin Biochem
, vol.31
, pp. 335-40
-
-
Sehgal, S.N.1
-
4
-
-
0042768010
-
Dyslipidemia in renal transplant recipients treated with a sirolimus and cyclosporine-based immunosuppressive regimen: Incidence, risk factors, progression, and prognosis
-
Chueh SC, Kahan BD. Dyslipidemia in renal transplant recipients treated with a sirolimus and cyclosporine-based immunosuppressive regimen: incidence, risk factors, progression, and prognosis. Transplantation 2003 76 : 375 82.
-
(2003)
Transplantation
, vol.76
, pp. 375-82
-
-
Chueh, S.C.1
Kahan, B.D.2
-
5
-
-
0034720548
-
Sirolimus-induced thrombocytopenia and leukopenia in renal transplant recipients: Risk factors, incidence, progression, and management
-
Hong JC, Kahan BD. Sirolimus-induced thrombocytopenia and leukopenia in renal transplant recipients: risk factors, incidence, progression, and management. Transplantation 2000 69 : 2085 90.
-
(2000)
Transplantation
, vol.69
, pp. 2085-90
-
-
Hong, J.C.1
Kahan, B.D.2
-
6
-
-
0041766132
-
Higher surgical wound complication rates with sirolimus immunosuppression after kidney transplantation: A matched-pair pilot study
-
Troppmann C, Pierce JL, Gandhi MM, et al. Higher surgical wound complication rates with sirolimus immunosuppression after kidney transplantation: a matched-pair pilot study. Transplantation 2003 76 : 426 9.
-
(2003)
Transplantation
, vol.76
, pp. 426-9
-
-
Troppmann, C.1
Pierce, J.L.2
Gandhi, M.M.3
-
7
-
-
0042863282
-
Comparison of sirolimus vs. mycophenolate mofetil on surgical complications and wound healing in adult kidney transplantation
-
Valente JF, Hricik D, Weigel K, et al. Comparison of sirolimus vs. mycophenolate mofetil on surgical complications and wound healing in adult kidney transplantation. Am J Transplant 2003 3 : 1128 34.
-
(2003)
Am J Transplant
, vol.3
, pp. 1128-34
-
-
Valente, J.F.1
Hricik, D.2
Weigel, K.3
-
8
-
-
0037183874
-
Incidence, therapy, and consequences of lymphocele after sirolimus-cyclosporine-prednisone immunosuppression in renal transplant recipients
-
Langer RM, Kahan BD. Incidence, therapy, and consequences of lymphocele after sirolimus-cyclosporine-prednisone immunosuppression in renal transplant recipients. Transplantation 2002 74 : 804 8.
-
(2002)
Transplantation
, vol.74
, pp. 804-8
-
-
Langer, R.M.1
Kahan, B.D.2
-
9
-
-
0033608450
-
Sirolimus: A potent new immunosuppressant for liver transplantation
-
Watson CJ, Friend PJ, Jamieson NV, et al. Sirolimus: a potent new immunosuppressant for liver transplantation. Transplantation 1999 67 : 505 9.
-
(1999)
Transplantation
, vol.67
, pp. 505-9
-
-
Watson, C.J.1
Friend, P.J.2
Jamieson, N.V.3
-
10
-
-
2542609091
-
Wound-healing complications after kidney transplantation: A prospective, randomized comparison of sirolimus and tacrolimus
-
Dean PG, Lund WJ, Larson TS, et al. Wound-healing complications after kidney transplantation: a prospective, randomized comparison of sirolimus and tacrolimus. Transplantation 2004 77 : 1555 61.
-
(2004)
Transplantation
, vol.77
, pp. 1555-61
-
-
Dean, P.G.1
Lund, W.J.2
Larson, T.S.3
-
11
-
-
0036275356
-
Hypoxia enhances vascular cell proliferation and angiogenesis in vitro via rapamycin (mTOR)-dependent signaling
-
Humar R, Kiefer FN, Berns H, et al. Hypoxia enhances vascular cell proliferation and angiogenesis in vitro via rapamycin (mTOR)-dependent signaling. FASEB J 2002 16 : 771 80.
-
(2002)
FASEB J
, vol.16
, pp. 771-80
-
-
Humar, R.1
Kiefer, F.N.2
Berns, H.3
-
12
-
-
0036225178
-
Inhibitors of mammalian target of rapamycin as novel antitumor agents: From bench to clinic
-
Huang S, Houghton PJ. Inhibitors of mammalian target of rapamycin as novel antitumor agents: from bench to clinic. Curr Opin Investig Drugs 2002 3 : 295 304.
-
(2002)
Curr Opin Investig Drugs
, vol.3
, pp. 295-304
-
-
Huang, S.1
Houghton, P.J.2
-
13
-
-
0036860261
-
The macrolide immunosuppressants in dermatology: Mechanisms of action
-
Marsland AM, Griffiths CE. The macrolide immunosuppressants in dermatology: mechanisms of action. Eur J Dermatol 2002 12 : 618 22.
-
(2002)
Eur J Dermatol
, vol.12
, pp. 618-22
-
-
Marsland, A.M.1
Griffiths, C.E.2
-
14
-
-
1942540090
-
Immunosuppressants and skin cancer in transplant patients: Focus on rapamycin
-
Euvrard S, Ulrich C, Lefrancois N. Immunosuppressants and skin cancer in transplant patients: focus on rapamycin. Dermatol Surg 2004 30 : 628 33.
-
(2004)
Dermatol Surg
, vol.30
, pp. 628-33
-
-
Euvrard, S.1
Ulrich, C.2
Lefrancois, N.3
-
16
-
-
27644436740
-
Maintenance immunosuppression with target-of-rapamycin inhibitors is associated with a reduced incidence of de novo malignancies
-
Kauffman HM, Cherikh WS, Cheng Y, et al. Maintenance immunosuppression with target-of-rapamycin inhibitors is associated with a reduced incidence of de novo malignancies. Transplantation 2005 80 : 883 9.
-
(2005)
Transplantation
, vol.80
, pp. 883-9
-
-
Kauffman, H.M.1
Cherikh, W.S.2
Cheng, Y.3
-
17
-
-
4043142865
-
Two-year incidence of malignancy in sirolimus-treated renal transplant recipients: Results from five multicenter studies
-
Mathew T, Kreis H, Friend P. Two-year incidence of malignancy in sirolimus-treated renal transplant recipients: results from five multicenter studies. Clin Transplant 2004 18 : 446 9.
-
(2004)
Clin Transplant
, vol.18
, pp. 446-9
-
-
Mathew, T.1
Kreis, H.2
Friend, P.3
-
18
-
-
0036174289
-
Rapamycin inhibits primary and metastatic tumor growth by antiangiogenesis: Involvement of vascular endothelial growth factor
-
Guba M, von Breitenbuch P, Steinbauer M, et al. Rapamycin inhibits primary and metastatic tumor growth by antiangiogenesis: involvement of vascular endothelial growth factor. Nat Med 2002 8 : 128 35.
-
(2002)
Nat Med
, vol.8
, pp. 128-35
-
-
Guba, M.1
Von Breitenbuch, P.2
Steinbauer, M.3
-
19
-
-
19044395914
-
Calcineurin inhibitor-induced chronic nephrotoxicity in liver transplant patients is reversible using rapamycin as the primary immunosuppressive agent
-
Cotterell AH, Fisher RA, King AL, et al. Calcineurin inhibitor-induced chronic nephrotoxicity in liver transplant patients is reversible using rapamycin as the primary immunosuppressive agent. Clin Transplant 2002 16 (Suppl) : 49 51.
-
(2002)
Clin Transplant
, vol.16
, pp. 49-51
-
-
Cotterell, A.H.1
Fisher, R.A.2
King, A.L.3
-
20
-
-
0037623516
-
Sirolimus therapy without calcineurin inhibitors: Necker Hospital 8-year experience
-
Morelon E, Kreis H. Sirolimus therapy without calcineurin inhibitors: Necker Hospital 8-year experience. Transplant Proc 2003 35 (Suppl) : 52S 7S.
-
(2003)
Transplant Proc
, vol.35
-
-
Morelon, E.1
Kreis, H.2
-
21
-
-
0034075822
-
Therapeutic drug monitoring of sirolimus: Correlations with efficacy and toxicity
-
Kahan BD, Napoli KL, Kelly PA, et al. Therapeutic drug monitoring of sirolimus: correlations with efficacy and toxicity. Clin Transplant 2000 14 : 97 109.
-
(2000)
Clin Transplant
, vol.14
, pp. 97-109
-
-
Kahan, B.D.1
Napoli, K.L.2
Kelly, P.A.3
-
22
-
-
0032410763
-
Hypertriglyceridemia in renal transplant recipients treated with sirolimus
-
Brattstrom C, Wilczek HE, Tyden G, et al. Hypertriglyceridemia in renal transplant recipients treated with sirolimus. Transplant Proc 1998 30 : 3950 1.
-
(1998)
Transplant Proc
, vol.30
, pp. 3950-1
-
-
Brattstrom, C.1
Wilczek, H.E.2
Tyden, G.3
-
23
-
-
0032525253
-
Hyperlipidemia in renal transplant recipients treated with sirolimus (rapamycin)
-
Brattstrom C, Wilczek H, Tyden G, et al. Hyperlipidemia in renal transplant recipients treated with sirolimus (rapamycin). Transplantation 1998 65 : 1272 4.
-
(1998)
Transplantation
, vol.65
, pp. 1272-4
-
-
Brattstrom, C.1
Wilczek, H.2
Tyden, G.3
-
24
-
-
0035879342
-
Sirolimus-associated eyelid edema in kidney transplant recipients
-
Mohaupt MG, Vogt B, Frey FJ. Sirolimus-associated eyelid edema in kidney transplant recipients. Transplantation 2001 72 : 162 4.
-
(2001)
Transplantation
, vol.72
, pp. 162-4
-
-
Mohaupt, M.G.1
Vogt, B.2
Frey, F.J.3
-
25
-
-
1942417799
-
Lymphedema associated with sirolimus in renal transplant recipients [Abstract #1311]
-
Aboujaoude WJ, Milgrom ML, Nayee LH, et al. Lymphedema associated with sirolimus in renal transplant recipients [Abstract #1311]. Am J Transplant 2003 3 (Suppl) : 488.
-
(2003)
Am J Transplant
, vol.3
, pp. 488
-
-
Aboujaoude, W.J.1
Milgrom, M.L.2
Nayee, L.H.3
-
26
-
-
0142137909
-
Sirolimus (SRL)-induced angioedema: Report of two cases [Abstract 1310]
-
Wadei H, Gruber S, Garnick J, et al. Sirolimus (SRL)-induced angioedema: report of two cases [Abstract 1310]. Am J Transplant 2003 3 (Suppl) : 488.
-
(2003)
Am J Transplant
, vol.3
, pp. 488
-
-
Wadei, H.1
Gruber, S.2
Garnick, J.3
-
27
-
-
0031006244
-
Effects of rapamycin on apoptosis of rheumatoid synovial cells
-
Migita K, Eguchi K, Ichinose Y, et al. Effects of rapamycin on apoptosis of rheumatoid synovial cells. Clin Exp Immunol 1997 108 : 199 203.
-
(1997)
Clin Exp Immunol
, vol.108
, pp. 199-203
-
-
Migita, K.1
Eguchi, K.2
Ichinose, Y.3
-
28
-
-
0345161813
-
Sirolimus (rapamycin)-based therapy in human renal transplantation: Similar efficacy and different toxicity compared with cyclosporine
-
Sirolimus European Renal Transplant Study Group.
-
Groth CG, Backman L, Morales JM, et al, Sirolimus European Renal Transplant Study Group. Sirolimus (rapamycin)-based therapy in human renal transplantation: similar efficacy and different toxicity compared with cyclosporine. Transplantation 1999 67 : 1036 42.
-
(1999)
Transplantation
, vol.67
, pp. 1036-42
-
-
Groth, C.G.1
Backman, L.2
Morales, J.M.3
-
29
-
-
0036707918
-
Delayed wound healing with sirolimus after liver transplant
-
Guilbeau JM. Delayed wound healing with sirolimus after liver transplant. Ann Pharmacother 2002 36 : 1391 5.
-
(2002)
Ann Pharmacother
, vol.36
, pp. 1391-5
-
-
Guilbeau, J.M.1
-
30
-
-
0032921290
-
Systemic toxicity following administration of sirolimus (formerly rapamycin) for psoriasis: Association of capillary leak syndrome with apoptosis of lesional lymphocytes
-
Kaplan MJ, Ellis CN, Bata-Csorgo Z, et al. Systemic toxicity following administration of sirolimus (formerly rapamycin) for psoriasis: association of capillary leak syndrome with apoptosis of lesional lymphocytes. Arch Dermatol 1999 135 : 553 7.
-
(1999)
Arch Dermatol
, vol.135
, pp. 553-7
-
-
Kaplan, M.J.1
Ellis, C.N.2
Bata-Csorgo, Z.3
-
31
-
-
38349194493
-
Rapamycin impairs the healing of the ureteric anastomosis [abstract]
-
Kahn D, Spearman W, Mall A, et al. Rapamycin impairs the healing of the ureteric anastomosis [abstract]. Transplantation 2004 78 (Suppl) : 259.
-
(2004)
Transplantation
, vol.78
, pp. 259
-
-
Kahn, D.1
Spearman, W.2
Mall, A.3
-
32
-
-
0038586466
-
Airway anastomotic dehiscence associated with use of sirolimus immediately after lung transplantation
-
King-Biggs MB, Dunitz JM, Park SJ, et al. Airway anastomotic dehiscence associated with use of sirolimus immediately after lung transplantation. Transplantation 2003 75 : 1437 43.
-
(2003)
Transplantation
, vol.75
, pp. 1437-43
-
-
King-Biggs, M.B.1
Dunitz, J.M.2
Park, S.J.3
|