The anti-diabetic drug metformin does not affect bone mass in vivo or fracture healing

Osteoporosis International

Volumn 24, Issue 10, 2013, Pages 2659-2670

  Jeyabalan, J ^a   Viollet, B ^b,c,d   Smitham, P ^e   Ellis, S A ^a   Zaman, G ^a   Bardin, C ^f   Goodship, A ^e   Roux, J P ^g   Pierre, M ^g   Chenu, C ^a  

^a ROYAL VETERINARY COLLEGE   (United Kingdom)

^b INSTITUT COCHIN   (France)

^c CNRS   (France)

^d UNIVERSITÉ PARIS DESCARTES   (France)

^e ROYAL NATIONAL ORTHOPAEDIC HOSPITAL   (United Kingdom)

^f ASSISTANCE PUBLIQUE HÔPITAUX DE PARIS   (France)

^g UNIVERSITÉ DE LYON   (France)

Author keywords

Bone architecture; Fracture healing; Histomorphometry; Metformin; Micro CT

Indexed keywords

DRINKING WATER; METFORMIN; SODIUM CHLORIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BONE MASS; BONE MINERAL; BONE RADIOGRAPHY; CALLUS; CELL ACTIVITY; CONTROLLED STUDY; ENCHONDRAL OSSIFICATION; FEEDING; FEMALE; FRACTURE HEALING; IN VIVO STUDY; MORPHOMETRICS; MOUSE; NONHUMAN; OSSIFICATION; OSTEOLYSIS; OSTEOTOMY; OVARIECTOMY; PRIORITY JOURNAL; RAT; RODENT; SHORT COURSE THERAPY; TRABECULAR BONE; TREATMENT DURATION; X RAY ANALYSIS;

AMP-ACTIVATED PROTEIN KINASES; ANIMALS; BONE DENSITY; BONE REMODELING; BONY CALLUS; ENZYME ACTIVATION; FEMALE; FEMORAL FRACTURES; FEMUR; FRACTURE HEALING; HYPOGLYCEMIC AGENTS; METFORMIN; MICE; MICE, INBRED C57BL; OSTEOPOROSIS; OVARIECTOMY; RATS; RATS, WISTAR; TIBIA; X-RAY MICROTOMOGRAPHY;

EID: 84885426684     PISSN: 0937941X     EISSN: 14332965     Source Type: Journal    
DOI: 10.1007/s00198-013-2371-0     Document Type: Article

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