메뉴 건너뛰기




Volumn 30, Issue 30, 2011, Pages 3305-3316

Fasting vs dietary restriction in cellular protection and cancer treatment: From model organisms to patients

Author keywords

chemotherapy; dietary restriction; differential stress resistance; fasting; starvation

Indexed keywords

GLUCOSE; SOMATOMEDIN C;

EID: 79960845908     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/onc.2011.91     Document Type: Review
Times cited : (245)

References (176)
  • 3
    • 48349110303 scopus 로고    scopus 로고
    • A low dose of dietary resveratrol partially mimics caloric restriction and retards aging parameters in mice
    • Barger JL, Kayo T, Vann JM, Arias EB, Wang J, Hacker TA et al. (2008). A low dose of dietary resveratrol partially mimics caloric restriction and retards aging parameters in mice. PLoS One 3: e2264.
    • (2008) PLoS One , vol.3
    • Barger, J.L.1    Kayo, T.2    Vann, J.M.3    Arias, E.B.4    Wang, J.5    Hacker, T.A.6
  • 4
    • 52849134315 scopus 로고    scopus 로고
    • Mechanisms of prolonged longevity: Mutants, knock-outs, and caloric restriction
    • Bartke A, Turyn D. (2001). Mechanisms of prolonged longevity: mutants, knock-outs, and caloric restriction. J Anti-aging Med 4: 197-203.
    • (2001) J Anti-aging Med , vol.4 , pp. 197-203
    • Bartke, A.1    Turyn, D.2
  • 5
    • 0001654493 scopus 로고
    • Fasting as an introduction to the treatment of obesity
    • Bloom WL. (1959). Fasting as an introduction to the treatment of obesity. Metabolism 8: 214-220.
    • (1959) Metabolism , vol.8 , pp. 214-220
    • Bloom, W.L.1
  • 6
    • 84887212549 scopus 로고    scopus 로고
    • Disruption of growth hormone receptor prevents calorie restriction from improving insulin action and longevity
    • Bonkowski MS, Dominici FP, Arum O, Rocha JS, Al Regaiey KA, Westbrook R et al. (2009). Disruption of growth hormone receptor prevents calorie restriction from improving insulin action and longevity. PLoS One 4: e4567.
    • (2009) PLoS One , vol.4
    • Bonkowski, M.S.1    Dominici, F.P.2    Arum, O.3    Rocha, J.S.4    Al Regaiey, K.A.5    Westbrook, R.6
  • 7
    • 61649102451 scopus 로고    scopus 로고
    • Intermittent calorie restriction delays prostate tumor detection and increases survival time in TRAMP mice
    • Bonorden MJ, Rogozina OP, Kluczny CM, Grossmann ME, Grambsch PL, Grande JP et al. (2009). Intermittent calorie restriction delays prostate tumor detection and increases survival time in TRAMP mice. Nutr Cancer 61: 265-275.
    • (2009) Nutr Cancer , vol.61 , pp. 265-275
    • Bonorden, M.J.1    Rogozina, O.P.2    Kluczny, C.M.3    Grossmann, M.E.4    Grambsch, P.L.5    Grande, J.P.6
  • 8
    • 0025933857 scopus 로고
    • Influence of age and long-term dietary restriction on plasma insulin-like growth factor-1 (IGF-1), IGF-1 gene expression, and IGF-1 binding proteins
    • Breese CR, Ingram RL, Sonntag WE. (1991). Influence of age and long-term dietary restriction on plasma insulin-like growth factor-1 (IGF-1), IGF-1 gene expression, and IGF-1 binding proteins. J Gerontol 46: B180-B187.
    • (1991) J Gerontol , vol.46
    • Breese, C.R.1    Ingram, R.L.2    Sonntag, W.E.3
  • 10
    • 0034027841 scopus 로고    scopus 로고
    • Catalase expression in delayed and premature aging mouse models
    • DOI 10.1016/S0531-5565(00)00079-6, PII S0531556500000796
    • Brown-Borg HM, Rakoczy SG. (2000). Catalase expression in delayed and premature aging mouse models. Exp Gerontol 35: 199-212. (Pubitemid 30190085)
    • (2000) Experimental Gerontology , vol.35 , Issue.2 , pp. 199-212
    • Brown-Borg, H.M.1    Rakoczy, S.G.2
  • 11
    • 0036485682 scopus 로고    scopus 로고
    • Effects of growth hormone and insulin-like growth factor-1 on hepatocyte antioxidative enzymes
    • Brown-Borg HM, Rakoczy SG, Romanick MA, Kennedy MA. (2002). Effects of growth hormone and insulin-like growth factor-1 on hepatocyte antioxidative enzymes. Exp Biol Med (Maywood) 227: 94-104.
    • (2002) Exp Biol Med (Maywood) , vol.227 , pp. 94-104
    • Brown-Borg, H.M.1    Rakoczy, S.G.2    Romanick, M.A.3    Kennedy, M.A.4
  • 12
    • 0033024623 scopus 로고    scopus 로고
    • DNA damage in deoxynucleosides and oligonucleotides treated with peroxynitrite
    • DOI 10.1021/tx980254m
    • Burney S, Niles JC, Dedon PC, Tannenbaum SR. (1999). DNA damage in deoxynucleosides and oligonucleotides treated with peroxynitrite. Chem Res Toxicol 12: 513-520. (Pubitemid 29282922)
    • (1999) Chemical Research in Toxicology , vol.12 , Issue.6 , pp. 513-520
    • Burney, S.1    Niles, J.C.2    Dedon, P.C.3    Tannenbaum, S.R.4
  • 13
  • 14
    • 0014946157 scopus 로고
    • Metabolic adaptation to prolonged starvation in man
    • Cahill Jr G, Felig P, Owen O, Wahren J. (1970). Metabolic adaptation to prolonged starvation in man. Nord Med 83: 89.
    • (1970) Nord Med , vol.83 , pp. 89
    • Cahill Jr., G.1    Felig, P.2    Owen, O.3    Wahren, J.4
  • 17
    • 0014954713 scopus 로고
    • Starvation in man
    • Cahill Jr GF. (1970). Starvation in man. N Engl J Med 282: 668-675.
    • (1970) N Engl J Med , vol.282 , pp. 668-675
    • Cahill Jr., G.F.1
  • 18
    • 33750110683 scopus 로고    scopus 로고
    • Fuel metabolism in starvation
    • Cahill Jr GF. (2006). Fuel metabolism in starvation. Annu Rev Nutr 26: 1-22.
    • (2006) Annu Rev Nutr , vol.26 , pp. 1-22
    • Cahill Jr., G.F.1
  • 19
    • 0014378427 scopus 로고
    • The consumption of fuels during prolonged starvation
    • Cahill Jr GJ, Owen OE, Morgan AP. (1968). The consumption of fuels during prolonged starvation. Adv Enzyme Regul 6: 143-150.
    • (1968) Adv Enzyme Regul , vol.6 , pp. 143-150
    • Cahill Jr., G.J.1    Owen, O.E.2    Morgan, A.P.3
  • 20
    • 64949135819 scopus 로고    scopus 로고
    • Does damage to DNA and other macromolecules play a role in aging? if so, how?
    • Campisi J, Vijg J. (2009). Does damage to DNA and other macromolecules play a role in aging? If so, how? J Gerontol A Biol Sci Med Sci 64: 175-178.
    • (2009) J Gerontol A Biol Sci Med Sci , vol.64 , pp. 175-178
    • Campisi, J.1    Vijg, J.2
  • 21
    • 11144242211 scopus 로고    scopus 로고
    • Timeline: Chemotherapy and the war on cancer
    • Chabner BA, Roberts Jr TG. (2005). Timeline: chemotherapy and the war on cancer. Nat Rev Cancer 5: 65-72.
    • (2005) Nat Rev Cancer , vol.5 , pp. 65-72
    • Chabner, B.A.1    Roberts Jr., T.G.2
  • 22
    • 34347394526 scopus 로고    scopus 로고
    • Collateral damage in cancer chemotherapy: Oxidative stress in nontargeted tissues
    • DOI 10.1124/mi.7.3.6
    • Chen Y, Jungsuwadee P, Vore M, Butterfield DA, St Clair DK. (2007). Collateral damage in cancer chemotherapy: oxidative stress in nontargeted tissues. Mol Interv 7: 147-156. (Pubitemid 47026725)
    • (2007) Molecular Interventions , vol.7 , Issue.3 , pp. 147-156
    • Chen, Y.1    Jungsuwadee, P.2    Vore, M.3    Butterfield, D.A.4    St. Clair, D.K.5
  • 23
    • 0035815414 scopus 로고    scopus 로고
    • Extension of life-span by loss of CHICO, a Drosophila insulin receptor substrate protein
    • DOI 10.1126/science.1057991
    • Clancy DJ, Gems D, Harshman LG, Oldham S, Stocker H, Hafen E et al. (2001). Extension of life-span by loss of CHICO, a Drosophila insulin receptor substrate protein. Science 292: 104-106. (Pubitemid 32289136)
    • (2001) Science , vol.292 , Issue.5514 , pp. 104-106
    • Clancy, D.J.1    Gems, D.2    Harshman, L.G.3    Oldham, S.4    Stocker, H.5    Hafen, E.6    Leevers, S.J.7    Partridge, L.8
  • 24
    • 0025817718 scopus 로고
    • Nutritional regulation of IGF-I and IGF binding proteins
    • Clemmons DR, Underwood LE. (1991). Nutritional regulation of IGF-I and IGF binding proteins. Annu Rev Nutr 11: 393-412. (Pubitemid 21903836)
    • (1991) Annual Review of Nutrition , vol.11 , Issue.1 , pp. 393-412
    • Clemmons, D.R.1    Underwood, L.E.2
  • 26
    • 9244261938 scopus 로고    scopus 로고
    • Chemotherapy-associated oxidative stress: Impact on chemotherapeutic effectiveness
    • DOI 10.1177/1534735404270335
    • Conklin KA. (2004). Chemotherapy-associated oxidative stress: impact on chemotherapeutic effectiveness. Integr Cancer Ther 3: 294-300. (Pubitemid 39552423)
    • (2004) Integrative Cancer Therapies , vol.3 , Issue.4 , pp. 294-300
    • Conklin, K.A.1
  • 27
    • 0034455827 scopus 로고    scopus 로고
    • Assessment of growth parameters and life span of GHR/BP gene-disrupted mice
    • DOI 10.1210/en.141.7.2608
    • Coschigano KT, Clemmons D, Bellush LL, Kopchick JJ. (2000). Assessment of growth parameters and life span of GHR/BP gene-disrupted mice. Endocrinology 141: 2608-2613. (Pubitemid 32269083)
    • (2000) Endocrinology , vol.141 , Issue.7 , pp. 2608-2613
    • Coschigano, K.T.1    Clemmons, D.2    Bellush, L.L.3    Kopchick, J.J.4
  • 28
    • 0001628206 scopus 로고
    • Lactic acidosis and death after the treatment of obesity by fasting
    • Cubberley PT, Polster SA, Schulman CL. (1965). Lactic acidosis and death after the treatment of obesity by fasting. N Engl J Med 272: 628-630.
    • (1965) N Engl J Med , vol.272 , pp. 628-630
    • Cubberley, P.T.1    Polster, S.A.2    Schulman, C.L.3
  • 29
    • 34250900982 scopus 로고    scopus 로고
    • Base-excision repair of oxidative DNA damage
    • DOI 10.1038/nature05978, PII NATURE05978
    • David SS, O'Shea VL, Kundu S. (2007). Base-excision repair of oxidative DNA damage. Nature 447: 941-950. (Pubitemid 46975761)
    • (2007) Nature , vol.447 , Issue.7147 , pp. 941-950
    • David, S.S.1    O'Shea, V.L.2    Kundu, S.3
  • 31
    • 0034626769 scopus 로고    scopus 로고
    • The age of cancer
    • DePinho RA. (2000). The age of cancer. Nature 408: 248-254.
    • (2000) Nature , vol.408 , pp. 248-254
    • Depinho, R.A.1
  • 32
    • 33845457114 scopus 로고    scopus 로고
    • Nutrition and physical activity during and after cancer treatment: An
    • American Cancer Society guide for informed choices
    • Doyle C, Kushi LH, Byers T, Courneya KS, Demark-Wahnefried W, Grant B et al. (2006). Nutrition and physical activity during and after cancer treatment: an American Cancer Society guide for informed choices. CA Cancer J Clin 56: 323-353.
    • (2006) CA Cancer J Clin , vol.56 , pp. 323-353
    • Doyle, C.1    Kushi, L.H.2    Byers, T.3    Courneya, K.S.4    Demark-Wahnefried, W.5    Grant, B.6
  • 33
    • 0002194861 scopus 로고
    • Prolonged starvation as treatment for severe obesity
    • Drenick EJ, Swendseid ME, Blahd WH, Tuttle SG. (1964). Prolonged starvation as treatment for severe obesity. JAMA 187: 100-105.
    • (1964) JAMA , vol.187 , pp. 100-105
    • Drenick, E.J.1    Swendseid, M.E.2    Blahd, W.H.3    Tuttle, S.G.4
  • 34
    • 0038242819 scopus 로고    scopus 로고
    • TRB3: A tribbles homolog that inhibits Akt/PKB activation by insulin in liver
    • DOI 10.1126/science.1079817
    • Du K, Herzig S, Kulkarni RN, Montminy M. (2003). TRB3: a tribbles homolog that inhibits Akt/PKB activation by insulin in liver. Science 300: 1574-1577. (Pubitemid 36682889)
    • (2003) Science , vol.300 , Issue.5625 , pp. 1574-1577
    • Du, K.1    Herzig, S.2    Kulkarni, R.N.3    Montminy, M.4
  • 35
    • 0030727705 scopus 로고    scopus 로고
    • Dietary restriction reduces insulin-like growth factor I levels, which modulates apoptosis, cell proliferation, and tumor progression in p53- deficient mice
    • Dunn SE, Kari FW, French J, Leininger JR, Travlos G, Wilson R et al. (1997). Dietary restriction reduces insulin-like growth factor I levels, which modulates apoptosis, cell proliferation, and tumor progression in p53-deficient mice. Cancer Res 57: 4667-4672. (Pubitemid 27468963)
    • (1997) Cancer Research , vol.57 , Issue.21 , pp. 4667-4672
    • Dunn, S.E.1    Kari, F.W.2    French, J.3    Leininger, J.R.4    Travlos, G.5    Wilson, R.6    Barrett, J.C.7
  • 37
    • 0028942050 scopus 로고
    • Lipid peroxidation products, and vitamin and trace element status in patients with cancer before and after chemotherapy, including adriamycin A preliminary study
    • Faber M, Coudray C, Hida H, Mousseau M, Favier A. (1995). Lipid peroxidation products, and vitamin and trace element status in patients with cancer before and after chemotherapy, including adriamycin. A preliminary study. Biol Trace Elem Res 47: 117-123.
    • (1995) Biol Trace Elem Res , vol.47 , pp. 117-123
    • Faber, M.1    Coudray, C.2    Hida, H.3    Mousseau, M.4    Favier, A.5
  • 38
    • 27744596999 scopus 로고    scopus 로고
    • Sir2 blocks extreme life-span extension
    • DOI 10.1016/j.cell.2005.08.042, PII S009286740500913X
    • Fabrizio P, Gattazzo C, Battistella L, Wei M, Cheng C, McGrew K et al. (2005). Sir2 blocks extreme life-span extension (see comment). Cell 123: 655-667. (Pubitemid 41608467)
    • (2005) Cell , vol.123 , Issue.4 , pp. 655-667
    • Fabrizio, P.1    Gattazzo, C.2    Battistella, L.3    Wei, M.4    Cheng, C.5    McGrew, K.6    Longo, V.D.7
  • 40
    • 0035853552 scopus 로고    scopus 로고
    • Regulation of longevity and stress resistance by Sch9 in yeast
    • DOI 10.1126/science.1059497
    • Fabrizio P, Pozza F, Pletcher SD, Gendron CM, Longo VD. (2001). Regulation of longevity and stress resistance by Sch9 in yeast. Science 292: 288-290. (Pubitemid 32295387)
    • (2001) Science , vol.292 , Issue.5515 , pp. 288-290
    • Fabrizio, P.1    Pozza, F.2    Pletcher, S.D.3    Gendron, C.M.4    Longo, V.D.5
  • 44
    • 33845500072 scopus 로고    scopus 로고
    • Long-term low-protein, low-calorie diet and endurance exercise modulate metabolic factors associated with cancer risk
    • Fontana L, Klein S, Holloszy JO. (2006). Long-term low-protein, low-calorie diet and endurance exercise modulate metabolic factors associated with cancer risk. Am J Clin Nutr 84: 1456-1462. (Pubitemid 44912831)
    • (2006) American Journal of Clinical Nutrition , vol.84 , Issue.6 , pp. 1456-1462
    • Fontana, L.1    Klein, S.2    Holloszy, J.O.3
  • 45
    • 77951176737 scopus 로고    scopus 로고
    • Extending healthy life span-from yeast to humans
    • Fontana L, Partridge L, Longo VD. (2010). Extending healthy life span-from yeast to humans. Science 328: 321-326.
    • (2010) Science , vol.328 , pp. 321-326
    • Fontana, L.1    Partridge, L.2    Longo, V.D.3
  • 46
    • 52449087974 scopus 로고    scopus 로고
    • Long-term effects of calorie or protein restriction on serum IGF-1 and IGFBP-3 concentration in humans
    • Fontana L, Weiss EP, Villareal DT, Klein S, Holloszy JO. (2008). Long-term effects of calorie or protein restriction on serum IGF-1 and IGFBP-3 concentration in humans. Aging Cell 7: 681-687.
    • (2008) Aging Cell , vol.7 , pp. 681-687
    • Fontana, L.1    Weiss, E.P.2    Villareal, D.T.3    Klein, S.4    Holloszy, J.O.5
  • 47
    • 68349106982 scopus 로고    scopus 로고
    • Estimation of Cachexia among cancer patients based on four definitions
    • Fox KM, Brooks JM, Gandra SR, Markus R, Chiou CF. (2009). Estimation of Cachexia among cancer patients based on four definitions. J Oncol 2009: 693458.
    • (2009) J Oncol , vol.2009 , pp. 693458
    • Fox, K.M.1    Brooks, J.M.2    Gandra, S.R.3    Markus, R.4    Chiou, C.F.5
  • 49
    • 0014662267 scopus 로고
    • Gross fragmentation of cardiac myofibrils after therapeutic starvation for obesity
    • Garnett ES, Barnard DL, Ford J, Goodbody RA, Woodehouse MA. (1969). Gross fragmentation of cardiac myofibrils after therapeutic starvation for obesity. Lancet 1: 914-916.
    • (1969) Lancet , vol.1 , pp. 914-916
    • Garnett, E.S.1    Barnard, D.L.2    Ford, J.3    Goodbody, R.A.4    Woodehouse, M.A.5
  • 50
    • 34247140294 scopus 로고    scopus 로고
    • Role of insulin-like signalling in Drosophila lifespan
    • DOI 10.1016/j.tibs.2007.02.007, PII S0968000407000643
    • Giannakou ME, Partridge L. (2007). Role of insulin-like signalling in Drosophila lifespan. Trends Biochem Sci 32: 180-188. (Pubitemid 46603282)
    • (2007) Trends in Biochemical Sciences , vol.32 , Issue.4 , pp. 180-188
    • Giannakou, M.E.1    Partridge, L.2
  • 51
    • 0024238665 scopus 로고
    • Protective effect of fasting upon cerebral hypoxic-ischemic injury
    • DOI 10.1007/BF00999535
    • Go KG, Prenen GH, Korf J. (1988). Protective effect of fasting upon cerebral hypoxic-ischemic injury. Metab Brain Dis 3: 257-263. (Pubitemid 19000683)
    • (1988) Metabolic Brain Disease , vol.3 , Issue.4 , pp. 257-263
    • Go, K.G.1    Prenen, G.H.M.2    Korf, J.3
  • 53
    • 0036974137 scopus 로고    scopus 로고
    • Initial cost of care results in medically supervised water-only fasting for treating high blood pressure and diabetes [2]
    • Goldhamer AC. (2002). Initial cost of care results in medically supervised water-only fasting for treating high blood pressure and diabetes. J Altern Complement Med 8: 696-697. (Pubitemid 36159745)
    • (2002) Journal of Alternative and Complementary Medicine , vol.8 , Issue.6 , pp. 696-697
    • Goldhamer, A.C.1
  • 54
    • 0020665205 scopus 로고
    • Differential effects of intermittent feeding and voluntary exercise on body weight and lifespan in adult rats
    • Goodrick CL, Ingram DK, Reynolds MA, Freeman JR, Cider NL. (1983). Differential effects of intermittent feeding and voluntary exercise on body weight and lifespan in adult rats. J Gerontol 38: 36-45. (Pubitemid 13217828)
    • (1983) Journals of Gerontology , vol.38 , Issue.1 , pp. 36-45
    • Goodrick, C.L.1    Ingram, D.K.2    Reynolds, M.A.3
  • 55
    • 69449097339 scopus 로고    scopus 로고
    • Emerging role of insulin-like growth factor receptor inhibitors in oncology: Early clinical trial results and future directions
    • Gualberto A, Pollak M. (2009). Emerging role of insulin-like growth factor receptor inhibitors in oncology: early clinical trial results and future directions. Oncogene 28: 3009-3021.
    • (2009) Oncogene , vol.28 , pp. 3009-3021
    • Gualberto, A.1    Pollak, M.2
  • 56
    • 0034626747 scopus 로고    scopus 로고
    • Genetic pathways that regulate ageing in model organisms
    • Guarente L, Kenyon C. (2000). Genetic pathways that regulate ageing in model organisms. Nature 408: 255-262.
    • (2000) Nature , vol.408 , pp. 255-262
    • Guarente, L.1    Kenyon, C.2
  • 57
    • 0034614637 scopus 로고    scopus 로고
    • The hallmarks of cancer
    • Hanahan D, Weinberg RA. (2000). The hallmarks of cancer. Cell 100: 57-70. (Pubitemid 30046295)
    • (2000) Cell , vol.100 , Issue.1 , pp. 57-70
    • Hanahan, D.1    Weinberg, R.A.2
  • 61
  • 62
    • 0022353888 scopus 로고
    • Lifetime breeding studies in fully fed and dietary restricted female CFY Sprague-Dawley rats. 1. Effect of age, housing conditions and diet on fecundity
    • DOI 10.1016/0047-6374(85)90106-X
    • Holehan AM, Merry BJ. (1985). Lifetime breeding studies in fully fed and dietary restricted female CFY Sprague-Dawley rats. 1. Effect of age, housing conditions and diet on fecundity. Mech Ageing Dev 33: 19-28. (Pubitemid 16206489)
    • (1985) Mechanisms of Ageing and Development , vol.33 , Issue.1 , pp. 19-28
    • Holehan, A.M.1    Merry, B.J.2
  • 63
    • 34447316421 scopus 로고    scopus 로고
    • Caloric restriction in humans
    • DOI 10.1016/j.exger.2007.03.009, PII S0531556507000630
    • Holloszy JO, Fontana L. (2007). Caloric restriction in humans. Exp Gerontol 42: 709-712. (Pubitemid 47058857)
    • (2007) Experimental Gerontology , vol.42 , Issue.8 , pp. 709-712
    • Holloszy, J.O.1    Fontana, L.2
  • 65
    • 59649120539 scopus 로고    scopus 로고
    • Signalling through RHEB-1 mediates intermittent fasting-induced longevity in Celegans
    • Honjoh S, Yamamoto T, Uno M, Nishida E. (2009). Signalling through RHEB-1 mediates intermittent fasting-induced longevity in Celegans. Nature 457: 726-730.
    • (2009) Nature , vol.457 , pp. 726-730
    • Honjoh, S.1    Yamamoto, T.2    Uno, M.3    Nishida, E.4
  • 66
    • 0038701745 scopus 로고    scopus 로고
    • Regulation of aging and age-related disease by DAF-16 and heat-shock factor
    • DOI 10.1126/science.1083701
    • Hsu AL, Murphy CT, Kenyon C. (2003). Regulation of aging and age-related disease by DAF-16 and heat-shock factor. Science 300: 1142-1145. (Pubitemid 36583098)
    • (2003) Science , vol.300 , Issue.5622 , pp. 1142-1145
    • Hsu, A.-L.1    Murphy, C.T.2    Kenyon, C.3
  • 67
    • 0013072999 scopus 로고    scopus 로고
    • Calorie Restriction, Aging, and Cancer Prevention: Mechanisms of Action and Applicability to Humans
    • DOI 10.1146/annurev.med.54.101601.152156
    • Hursting SD, Lavigne JA, Berrigan D, Perkins SN, Barrett JC. (2003). Calorie restriction, aging, and cancer prevention: mechanisms of action and applicability to humans. Annu Rev Med 54: 131-152. (Pubitemid 37386388)
    • (2003) Annual Review of Medicine , vol.54 , pp. 131-152
    • Hursting, S.D.1    Lavigne, J.A.2    Berrigan, D.3    Perkins, S.N.4    Barrett, J.C.5
  • 70
    • 0038363836 scopus 로고    scopus 로고
    • Nutritional and hormonal factors control the gene expression of FoxOs, the mammalian homologues of DAF-16
    • DOI 10.1677/jme.0.0300253
    • Imae M, Fu Z, Yoshida A, Noguchi T, Kato H. (2003). Nutritional and hormonal factors control the gene expression of FoxOs, the mammalian homologues of DAF-16. J Mol Endocrinol 30: 253-262. (Pubitemid 36592517)
    • (2003) Journal of Molecular Endocrinology , vol.30 , Issue.2 , pp. 253-262
    • Imae, M.1    Fu, Z.2    Yoshida, A.3    Noguchi, T.4    Kato, H.5
  • 71
    • 0020691830 scopus 로고
    • Dietary components that regulate serum somatomedin-C concentrations in humans
    • Isley WL, Underwood LE, Clemmons DR. (1983). Dietary components that regulate serum somatomedin-C concentrations in humans. J Clin Invest 1: 175-182. (Pubitemid 13137481)
    • (1983) Journal of Clinical Investigation , vol.71 , Issue.2 , pp. 175-182
    • Isley, W.L.1    Underwood, L.E.2    Clemmons, D.R.3
  • 73
    • 0023761363 scopus 로고
    • Starvation-induced cross protection against heat or H2O2 challenge in Escherichia coli
    • Jenkins DE, Schultz JE, Matin A. (1988). Starvation-induced cross protection against heat or H2O2 challenge in Escherichia coli. J Bacteriol 170: 3910-3914.
    • (1988) J Bacteriol , vol.170 , pp. 3910-3914
    • Jenkins, D.E.1    Schultz, J.E.2    Matin, A.3
  • 74
    • 0025004091 scopus 로고
    • Increased life-span of age-1 mutants in Caenorhabditis elegans and lower Gompertz rate of aging
    • Johnson TE. (1990). Increased life-span of age-1 mutants in Caenorhabditis elegans and lower Gompertz rate of aging. Science 249: 908-912.
    • (1990) Science , vol.249 , pp. 908-912
    • Johnson, T.E.1
  • 75
    • 34247390126 scopus 로고    scopus 로고
    • Fasting - The ultimate diet?
    • Johnstone AM. (2007). Fasting-the ultimate diet? Obes Rev 8: 211-222.
    • (2007) Obes Rev , vol.8 , pp. 211-222
    • Johnstone, A.M.1
  • 76
    • 77956170799 scopus 로고    scopus 로고
    • Preneoplastic changes persist after IGF-IR downregulation and tumor regression
    • Jones RA, Petrik JJ, Moorehead RA. (2010). Preneoplastic changes persist after IGF-IR downregulation and tumor regression. Oncogene 29: 4779-4786.
    • (2010) Oncogene , vol.29 , pp. 4779-4786
    • Jones, R.A.1    Petrik, J.J.2    Moorehead, R.A.3
  • 77
    • 64749108996 scopus 로고    scopus 로고
    • Tumours with PI3K activation are resistant to dietary restriction
    • Kalaany NY, Sabatini DM. (2009). Tumours with PI3K activation are resistant to dietary restriction. Nature 458: 725-731.
    • (2009) Nature , vol.458 , pp. 725-731
    • Kalaany, N.Y.1    Sabatini, D.M.2
  • 78
    • 20444403067 scopus 로고    scopus 로고
    • They starved so that others be better fed: Remembering ancel keys and the Minnesota experiment
    • Kalm LM, Semba RD. (2005). They starved so that others be better fed: remembering Ancel Keys and the Minnesota experiment. J Nutr 135: 1347-1352. (Pubitemid 40799594)
    • (2005) Journal of Nutrition , vol.135 , Issue.6 , pp. 1347-1352
    • Kalm, L.M.1    Semba, R.D.2
  • 79
    • 0033604585 scopus 로고    scopus 로고
    • The regulation and activities of the multifunctional serine/threonine kinase Akt/PKB
    • Kandel ES, Hay N. (1999). The regulation and activities of the multifunctional serine/threonine kinase Akt/PKB. Exp Cell Res 253: 210-229.
    • (1999) Exp Cell Res , vol.253 , pp. 210-229
    • Kandel, E.S.1    Hay, N.2
  • 80
    • 0035917440 scopus 로고    scopus 로고
    • A conserved regulatory system for aging
    • DOI 10.1016/S0092-8674(01)00306-3
    • Kenyon C. (2001). A conserved regulatory system for aging. Cell 105: 165-168. (Pubitemid 32429505)
    • (2001) Cell , vol.105 , Issue.2 , pp. 165-168
    • Kenyon, C.1
  • 83
    • 0030592517 scopus 로고    scopus 로고
    • Lessons from hereditary colorectal cancer
    • DOI 10.1016/S0092-8674(00)81333-1
    • Kinzler KW, Vogelstein B. (1996). Lessons from hereditary colorectal cancer. Cell 87: 159-170. (Pubitemid 26358996)
    • (1996) Cell , vol.87 , Issue.2 , pp. 159-170
    • Kinzler, K.W.1    Vogelstein, B.2
  • 84
    • 0026638153 scopus 로고
    • Mitotic activity in mice is suppressed by energy restriction-induced torpor
    • Koizumi A, Tsukada M, Wada Y, Masuda H, Weindruch R. (1992). Mitotic activity in mice is suppressed by energy restriction-induced torpor. J Nutr 122: 1446-1453.
    • (1992) J Nutr , vol.122 , pp. 1446-1453
    • Koizumi, A.1    Tsukada, M.2    Wada, Y.3    Masuda, H.4    Weindruch, R.5
  • 85
    • 50949120511 scopus 로고    scopus 로고
    • Calorie restriction and susceptibility to intact pathogens
    • Kristan DM. (2008). Calorie restriction and susceptibility to intact pathogens. Age (Dordr) 30: 147-156.
    • (2008) Age (Dordr) , vol.30 , pp. 147-156
    • Kristan, D.M.1
  • 87
    • 78649338141 scopus 로고    scopus 로고
    • Autophagy and the integrated stress response
    • Kroemer G, Marino G, Levine B. (2010). Autophagy and the integrated stress response. Mol Cell 40: 280-293.
    • (2010) Mol Cell , vol.40 , pp. 280-293
    • Kroemer, G.1    Marino, G.2    Levine, B.3
  • 89
    • 76749169812 scopus 로고    scopus 로고
    • Reduced levels of IGF-I mediate differential protection of normal and cancer cells in response to fasting and improve chemotherapeutic index
    • Lee C, Safdie FM, Raffaghello L, Wei M, Madia F, Parrella E et al. (2010). Reduced levels of IGF-I mediate differential protection of normal and cancer cells in response to fasting and improve chemotherapeutic index. Cancer Res 70: 1564-1572.
    • (2010) Cancer Res , vol.70 , pp. 1564-1572
    • Lee, C.1    Safdie, F.M.2    Raffaghello, L.3    Wei, M.4    Madia, F.5    Parrella, E.6
  • 90
    • 70350365110 scopus 로고    scopus 로고
    • Glucose shortens the life span of C. elegans by downregulating DAF-16/FOXO activity and aquaporin gene expression
    • Lee SJ, Murphy CT, Kenyon C. (2009). Glucose shortens the life span of C. elegans by downregulating DAF-16/FOXO activity and aquaporin gene expression. Cell Metab 10: 379-391.
    • (2009) Cell Metab , vol.10 , pp. 379-391
    • Lee, S.J.1    Murphy, C.T.2    Kenyon, C.3
  • 91
    • 45549096918 scopus 로고    scopus 로고
    • SirT1 Inhibition Reduces IGF-I/IRS-2/Ras/ERK1/2 Signaling and Protects Neurons
    • DOI 10.1016/j.cmet.2008.05.004, PII S1550413108001484
    • Li Y, Xu W, McBurney MW, Longo VD. (2008). SirT1 inhibition reduces IGF-I/IRS-2/Ras/ERK1/2 signaling and protects neurons. Cell Metab 8: 38-48. (Pubitemid 351859225)
    • (2008) Cell Metabolism , vol.8 , Issue.1 , pp. 38-48
    • Li, Y.1    Xu, W.2    McBurney, M.W.3    Longo, V.D.4
  • 92
    • 0033014520 scopus 로고    scopus 로고
    • Chemoprotectants: A review of their clinical pharmacology and therapeutic efficacy
    • DOI 10.2165/00003495-199957030-00003
    • Links M, Lewis C. (1999). Chemoprotectants: a review of their clinical pharmacology and therapeutic efficacy. Drugs 57: 293-308. (Pubitemid 29137477)
    • (1999) Drugs , vol.57 , Issue.3 , pp. 293-308
    • Links, M.1    Lewis, C.2
  • 94
    • 0033405860 scopus 로고    scopus 로고
    • Mutations in signal transduction proteins increase stress resistance and longevity in yeast, nematodes, fruit flies, and mammalian neuronal cells
    • DOI 10.1016/S0197-4580(99)00089-5, PII S0197458099000895
    • Longo VD. (1999). Mutations in signal transduction proteins increase stress resistance and longevity in yeast, nematodes, fruit flies, and mammalian neuronal cells. Neurobiol Aging 20: 479-486. (Pubitemid 30001461)
    • (1999) Neurobiology of Aging , vol.20 , Issue.5 , pp. 479-486
    • Longo, V.D.1
  • 95
    • 0031009829 scopus 로고    scopus 로고
    • Human Bcl-2 reverses survival defects in yeast lacking superoxide dismutase and delays death of wild-type yeast
    • DOI 10.1083/jcb.137.7.1581
    • Longo VD, Ellerby LM, Bredesen DE, Valentine JS, Gralla EB. (1997). Human Bcl-2 reverses survival defects in yeast lacking superoxide dismutase and delays death of wild-type yeast. J Cell Biol 137: 1581-1588. (Pubitemid 27282238)
    • (1997) Journal of Cell Biology , vol.137 , Issue.7 , pp. 1581-1588
    • Longo, V.D.1    Ellerby, L.M.2    Bredesen, D.E.3    Valentine, J.S.4    Gralla, E.B.5
  • 96
    • 0037470488 scopus 로고    scopus 로고
    • Evolutionary medicine: From dwarf model systems to healthy centenarians?
    • DOI 10.1126/science.1077991
    • Longo VD, Finch CE. (2003a). Evolutionary medicine: from dwarf model systems to healthy centenarians? Science 299: 1342-1346. (Pubitemid 36254638)
    • (2003) Science , vol.299 , Issue.5611 , pp. 1342-1346
    • Longo, V.D.1    Finch, C.E.2
  • 97
    • 0037470488 scopus 로고    scopus 로고
    • Evolutionary medicine: From dwarf model systems to healthy centenarians?
    • DOI 10.1126/science.1077991
    • Longo VD, Finch CE. (2003b). Evolutionary medicine: from dwarf model systems to healthy centenarians? Science 299: 1342-1346. (Pubitemid 36254638)
    • (2003) Science , vol.299 , Issue.5611 , pp. 1342-1346
    • Longo, V.D.1    Finch, C.E.2
  • 98
    • 75249094454 scopus 로고    scopus 로고
    • Calorie restriction and cancer prevention: Metabolic and molecular mechanisms
    • Longo VD, Fontana L. (2010). Calorie restriction and cancer prevention: metabolic and molecular mechanisms. Trends Pharmacol Sci 31: 89-98.
    • (2010) Trends Pharmacol Sci , vol.31 , pp. 89-98
    • Longo, V.D.1    Fontana, L.2
  • 99
    • 0028366572 scopus 로고
    • Lipid peroxides in the polychemotherapy of cancer patients
    • Look MP, Musch E. (1994). Lipid peroxides in the polychemotherapy of cancer patients. Chemotherapy 40: 8-15. (Pubitemid 23360156)
    • (1994) Chemotherapy , vol.40 , Issue.1 , pp. 8-15
    • Look, M.P.1    Musch, E.2
  • 100
    • 61449182121 scopus 로고    scopus 로고
    • Principles of cancer therapy: Oncogene and non-oncogene addiction
    • Luo J, Solimini NL, Elledge SJ. (2009). Principles of cancer therapy: oncogene and non-oncogene addiction. Cell 136: 823-837.
    • (2009) Cell , vol.136 , pp. 823-837
    • Luo, J.1    Solimini, N.L.2    Elledge, S.J.3
  • 102
    • 0034896661 scopus 로고    scopus 로고
    • Effects of 36 hour fasting on GH/IGF-I axis and metabolic parameters in patients with simple obesity. Comparison with normal subjects and hypopituitary patients with severe GH deficiency
    • DOI 10.1038/sj.ijo.0801671
    • Maccario M, Aimaretti G, Grottoli S, Gauna C, Tassone F, Corneli G et al. (2001). Effects of 36h fasting on GH/IGF-I axis and metabolic parameters in patients with simple obesity. Comparison with normal subjects and hypopituitary patients with severe GH deficiency. Int J Obes Relat Metab Disord 25: 1233-1239. (Pubitemid 32721547)
    • (2001) International Journal of Obesity , vol.25 , Issue.8 , pp. 1233-1239
    • Maccario, M.1    Aimaretti, G.2    Grottoli, S.3    Gauna, C.4    Tassone, F.5    Corneli, G.6    Rossetto, R.7    Wu, Z.8    Strasburger, C.J.9    Ghigo, E.10
  • 103
    • 38349018367 scopus 로고    scopus 로고
    • Longevity mutation in SCH9 prevents recombination errors and premature genomic instability in a Werner/Bloom model system
    • Madia F, Gattazzo C, Wei M, Fabrizio P, Burhans WC, Weinberger M et al. (2008). Longevity mutation in SCH9 prevents recombination errors and premature genomic instability in a Werner/Bloom model system. J Cell Biol 180: 67-81.
    • (2008) J Cell Biol , vol.180 , pp. 67-81
    • Madia, F.1    Gattazzo, C.2    Wei, M.3    Fabrizio, P.4    Burhans, W.C.5    Weinberger, M.6
  • 104
    • 69449102913 scopus 로고    scopus 로고
    • Oncogene homologue Sch9 promotes age-dependent mutations by a superoxide and Rev1/Polzeta-dependent mechanism
    • Madia F, Wei M, Yuan V, Hu J, Gattazzo C, Pham P et al. (2009). Oncogene homologue Sch9 promotes age-dependent mutations by a superoxide and Rev1/Polzeta-dependent mechanism. J Cell Biol 186: 509-523.
    • (2009) J Cell Biol , vol.186 , pp. 509-523
    • Madia, F.1    Wei, M.2    Yuan, V.3    Hu, J.4    Gattazzo, C.5    Pham, P.6
  • 105
    • 0025308684 scopus 로고
    • Fasting prior to transient cerebral ischemia reduces delayed neuronal necrosis
    • DOI 10.1007/BF01001047
    • Marie C, Bralet AM, Gueldry S, Bralet J. (1990). Fasting prior to transient cerebral ischemia reduces delayed neuronal necrosis. Metab Brain Dis 5: 65-75. (Pubitemid 20235307)
    • (1990) Metabolic Brain Disease , vol.5 , Issue.2 , pp. 65-75
    • Marie, C.1    Bralet, A.-M.2    Gueldry, S.3    Bralet, J.4
  • 106
    • 77953849832 scopus 로고    scopus 로고
    • Ammonia: A diffusible factor released by proliferating cells that induces autophagy
    • Marino G, Kroemer G. (2010). Ammonia: a diffusible factor released by proliferating cells that induces autophagy. Sci Signal 3: pe19.
    • (2010) Sci Signal , vol.3
    • Marino, G.1    Kroemer, G.2
  • 107
    • 0006171428 scopus 로고
    • Temporary nutritional stress and infertility in female mice
    • McClure TJ. (1959). Temporary nutritional stress and infertility in female mice. J Physiol 147: 221-225.
    • (1959) J Physiol , vol.147 , pp. 221-225
    • McClure, T.J.1
  • 108
    • 77956334156 scopus 로고    scopus 로고
    • Insulin-like signaling determines survival during stress via posttranscriptional mechanisms in C. elegans
    • McColl G, Rogers AN, Alavez S, Hubbard AE, Melov S, Link CD et al. (2010). Insulin-like signaling determines survival during stress via posttranscriptional mechanisms in C. elegans. Cell Metab 12: 260-272.
    • (2010) Cell Metab , vol.12 , pp. 260-272
    • McColl, G.1    Rogers, A.N.2    Alavez, S.3    Hubbard, A.E.4    Melov, S.5    Link, C.D.6
  • 112
    • 0016166139 scopus 로고
    • Growth hormone secretion in starvation: A reassessment
    • Merimee TJ, Fineberg SE. (1974). Growth hormone secretion in starvation: a reassessment. J Clin Endocrinol Metab 39: 385-386.
    • (1974) J Clin Endocrinol Metab , vol.39 , pp. 385-386
    • Merimee, T.J.1    Fineberg, S.E.2
  • 114
    • 24644478043 scopus 로고    scopus 로고
    • Incorporation of fasting therapy in an integrative medicine ward: Evaluation of outcome, safety, and effects on lifestyle adherence in a large prospective cohort study
    • DOI 10.1089/acm.2005.11.601
    • Michalsen A, Hoffmann B, Moebus S, Backer M, Langhorst J, Dobos GJ. (2005). Incorporation of fasting therapy in an integrative medicine ward: evaluation of outcome, safety, and effects on lifestyle adherence in a large prospective cohort study. J Altern Complement Med 11: 601-607. (Pubitemid 41279075)
    • (2005) Journal of Alternative and Complementary Medicine , vol.11 , Issue.4 , pp. 601-607
    • Michalsen, A.1    Hoffmann, B.2    Moebus, S.3    Backer, M.4    Langhorst, J.5    Dobos, G.J.6
  • 116
    • 76249106732 scopus 로고    scopus 로고
    • Short-term dietary restriction and fasting precondition against ischemia reperfusion injury in mice
    • Mitchell JR, Verweij M, Brand K, van de Ven M, Goemaere N, van den Engel S et al. (2009). Short-term dietary restriction and fasting precondition against ischemia reperfusion injury in mice. Aging Cell 9: 40-53.
    • (2009) Aging Cell , vol.9 , pp. 40-53
    • Mitchell, J.R.1    Verweij, M.2    Brand, K.3    Van De Ven, M.4    Goemaere, N.5    Van Den Engel, S.6
  • 117
    • 65249171425 scopus 로고    scopus 로고
    • Effects of growth hormone on glucose, lipid, and protein metabolism in human subjects
    • Moller N, Jorgensen JO. (2009). Effects of growth hormone on glucose, lipid, and protein metabolism in human subjects. Endocr Rev 30: 152-177.
    • (2009) Endocr Rev , vol.30 , pp. 152-177
    • Moller, N.1    Jorgensen, J.O.2
  • 118
    • 0000066687 scopus 로고
    • Beziehungen zwischen Ernahrung und Tumor-wachstum
    • Moreschi C. (1909). Beziehungen zwischen Ernahrung und Tumor-wachstum. Z für Immunitätsforsch 2: 651-675.
    • (1909) Z für Immunitätsforsch , vol.2 , pp. 651-675
    • Moreschi, C.1
  • 119
    • 0029768753 scopus 로고    scopus 로고
    • A phosphatidylinositol-3-OH kinase family member regulating longevity and diapause in Caenorhabditis elegans
    • DOI 10.1038/382536a0
    • Morris JZ, Tissenbaum HA, Ruvkun G. (1996). A phospatidylinositol-3-OH kinase family member regulating longevity and diapause in Caenorhbditis elegans. Nature 382: 536-539. (Pubitemid 26260694)
    • (1996) Nature , vol.382 , Issue.6591 , pp. 536-539
    • Morris, J.Z.1    Tissenbaum, H.A.2    Ruvkun, G.3
  • 121
    • 4143146391 scopus 로고    scopus 로고
    • Antiangiogenic and proapoptotic effects of dietary restriction on experimental mouse and human brain tumors
    • DOI 10.1158/1078-0432.CCR-04-0308
    • Mukherjee P, Abate LE, Seyfried TN. (2004). Antiangiogenic and proapoptotic effects of dietary restriction on experimental mouse and human brain tumors. Clin Cancer Res 10: 5622-5629. (Pubitemid 39100504)
    • (2004) Clinical Cancer Research , vol.10 , Issue.16 , pp. 5622-5629
    • Mukherjee, P.1    Abate, L.E.2    Seyfried, T.N.3
  • 122
    • 0032952176 scopus 로고    scopus 로고
    • Neuroendocrine control of growth hormone secretion
    • Muller EE, Locatelli V, Cocchi D. (1999). Neuroendocrine control of growth hormone secretion. Physiol Rev 79: 511-607. (Pubitemid 29210930)
    • (1999) Physiological Reviews , vol.79 , Issue.2 , pp. 511-607
    • Muller, E.E.1    Locatelli, V.2    Cocchi, D.3
  • 123
    • 33751402849 scopus 로고    scopus 로고
    • Stress resistance in long-lived mouse models
    • DOI 10.1016/j.exger.2006.06.061, PII S0531556506002361
    • Murakami S. (2006). Stress resistance in long-lived mouse models. Exp Gerontol 41: 1014-1019. (Pubitemid 44821697)
    • (2006) Experimental Gerontology , vol.41 , Issue.10 , pp. 1014-1019
    • Murakami, S.1
  • 124
    • 0021792065 scopus 로고
    • The role of high rates of glycolysis and glutamine utilization in rapidly dividing cells
    • DOI 10.1007/BF01116556
    • Newsholme EA, Crabtree B, Ardawi MS. (1985). The role of high rates of glycolysis and glutamine utilization in rapidly dividing cells. Biosci Rep 5: 393-400. (Pubitemid 15067685)
    • (1985) Bioscience Reports , vol.5 , Issue.5 , pp. 393-400
    • Newsholme, E.A.1    Crabtree, B.2    Ardawi, M.S.M.3
  • 125
    • 15944407209 scopus 로고    scopus 로고
    • The metabolic role of growth hormone in humans with particular reference to fasting
    • DOI 10.1016/j.ghir.2005.02.005, PII S1096637405000201
    • Norrelund H. (2005). The metabolic role of growth hormone in humans with particular reference to fasting. Growth Horm IGF Res 15: 95-122. (Pubitemid 40443811)
    • (2005) Growth Hormone and IGF Research , vol.15 , Issue.2 , pp. 95-122
    • Norrelund, H.1
  • 126
    • 0017337163 scopus 로고
    • 3 in healthy males
    • Palmblad J, Levi L, Burger A, Melander A, Westgren U, von Schenck H et al. (1977). Effects of total energy withdrawal (fasting) on the levels of growth hormone, thyrotropin, cortisol, adrenaline, noradrenaline, T4, T3, and rT3 in healthy males. Acta Med Scand 201: 15-22. (Pubitemid 8027091)
    • (1977) Acta Medica Scandinavica , vol.201 , Issue.1-2 , pp. 15-22
    • Palmblad, J.1    Levi, L.2    Burger, A.3
  • 127
    • 0033151613 scopus 로고    scopus 로고
    • A PDK1 homolog is necessary and sufficient to transduce AGE-1 PI3 kinase signals that regulate diapause in Caenorhabditis elegans
    • Paradis S, Ailion M, Toker A, Thomas JH, Ruvkun G. (1999). A PDK1 homolog is necessary and sufficient to transduce AGE-1 PI3 kinase signals that regulate diapause in Caenorhabditis elegans. Genes Dev 13: 1438-1452. (Pubitemid 29270248)
    • (1999) Genes and Development , vol.13 , Issue.11 , pp. 1438-1452
    • Paradis, S.1    Ailion, M.2    Toker, A.3    Thomas, J.H.4    Ruvkun, G.5
  • 133
    • 0014958784 scopus 로고
    • Prolonged starvation - A dangerous procedure?
    • Runcie J, Thomson TJ. (1970). Prolonged starvation-a dangerous procedure? Br Med J 3: 432-435.
    • (1970) Br Med J , vol.3 , pp. 432-435
    • Runcie, J.1    Thomson, T.J.2
  • 134
    • 0025935566 scopus 로고
    • Assessment of the role of the glucocorticoid system in aging processes and in the action of food restriction
    • Sabatino F, Masoro EJ, McMahan CA, Kuhn RW. (1991). Assessment of the role of the glucocorticoid system in aging processes and in the action of food restriction. J Gerontol 46: B171-B179.
    • (1991) J Gerontol , vol.46
    • Sabatino, F.1    Masoro, E.J.2    McMahan, C.A.3    Kuhn, R.W.4
  • 135
    • 77953642929 scopus 로고    scopus 로고
    • Fasting and cancer treatments in humans: A case series report
    • Safdie FM, Dorff T, Quinn D, Fontana L, Wei M, Lee C et al. (2009). Fasting and cancer treatments in humans: a case series report. Aging 1: 988-1007.
    • (2009) Aging , vol.1 , pp. 988-1007
    • Safdie, F.M.1    Dorff, T.2    Quinn, D.3    Fontana, L.4    Wei, M.5    Lee, C.6
  • 137
    • 0025055087 scopus 로고
    • Free radical generation in human leukocytes by CIS-unsaturated fatty acids is a calmodulin dependent process
    • DOI 10.1016/0952-3278(90)90167-J
    • Sangeetha P, Das UN, Koratkar R. (1990). Free radical generation in human leukocytes by CIS-unsaturated fatty acids is a calmodulin dependent process. Prostaglandins Leukot Essent Fatty Acids 39: 27-30. (Pubitemid 20068150)
    • (1990) Prostaglandins Leukotrienes and Essential Fatty Acids , vol.39 , Issue.1 , pp. 27-30
    • Sangeetha, P.1    Das, U.N.2    Korathar, R.3
  • 139
    • 0017227340 scopus 로고
    • The metabolic events of starvation
    • Saudek CD, Felig P. (1976). The metabolic events of starvation. Am J Med 60: 117-126.
    • (1976) Am J Med , vol.60 , pp. 117-126
    • Saudek, C.D.1    Felig, P.2
  • 140
    • 0023072659 scopus 로고
    • The phenomenon of famine
    • Scrimshaw NS. (1987). The phenomenon of famine. Annu Rev Nutr 7: 1-21.
    • (1987) Annu Rev Nutr , vol.7 , pp. 1-21
    • Scrimshaw, N.S.1
  • 142
    • 0033796568 scopus 로고    scopus 로고
    • Neurotrophic factors influence upregulation of constitutive isoform of heme oxygenase and cellular stress response in the spinal cord following trauma. An experimental study using immunohistochem-istry in the rat
    • Sharma HS, Nyberg F, Gordh T, Alm P, Westman J. (2000). Neurotrophic factors influence upregulation of constitutive isoform of heme oxygenase and cellular stress response in the spinal cord following trauma. An experimental study using immunohistochem-istry in the rat. Amino Acids 19: 351-361.
    • (2000) Amino Acids , vol.19 , pp. 351-361
    • Sharma, H.S.1    Nyberg, F.2    Gordh, T.3    Alm, P.4    Westman, J.5
  • 143
    • 77956249320 scopus 로고    scopus 로고
    • Calorie restriction as an anti-invasive therapy for malignant brain cancer in the VM mouse
    • Shelton LM, Huysentruyt LC, Mukherjee P, Seyfried TN. (2010). Calorie restriction as an anti-invasive therapy for malignant brain cancer in the VM mouse. ASN Neuro 2: 171-176.
    • (2010) ASN Neuro , vol.2 , pp. 171-176
    • Shelton, L.M.1    Huysentruyt, L.C.2    Mukherjee, P.3    Seyfried, T.N.4
  • 145
    • 0038380473 scopus 로고    scopus 로고
    • Life span extension by reduction of the growth hormone-insulin-like growth factor-1 axis: Relation to caloric restriction
    • Shimokawa I, Higami Y, Tsuchiya T, Otani H, Komatsu T, Chiba T et al. (2003). Life span extension by reduction of the growth hormone-insulin-like growth factor-1 axis: relation to caloric restriction. FASEB J 17: 1108-1109.
    • (2003) FASEB J , vol.17 , pp. 1108-1109
    • Shimokawa, I.1    Higami, Y.2    Tsuchiya, T.3    Otani, H.4    Komatsu, T.5    Chiba, T.6
  • 146
    • 0014425696 scopus 로고
    • Death during therapeutic starvation
    • Spencer IO. (1968). Death during therapeutic starvation. Lancet 2: 679-680.
    • (1968) Lancet , vol.2 , pp. 679-680
    • Spencer, I.O.1
  • 147
    • 0025672628 scopus 로고
    • Dietary energy restriction in mice reduces hepatic expression of glucose-regulated protein 78 (BiP) and 94 mRNA
    • Spindler SR, Crew MD, Mote PL, Grizzle JM, Walford RL. (1990). Dietary energy restriction in mice reduces hepatic expression of glucose-regulated protein 78 (BiP) and 94 mRNA. J Nutr 120: 1412-1417.
    • (1990) J Nutr , vol.120 , pp. 1412-1417
    • Spindler, S.R.1    Crew, M.D.2    Mote, P.L.3    Grizzle, J.M.4    Walford, R.L.5
  • 148
    • 0034536065 scopus 로고    scopus 로고
    • Dietary restriction of single essential amino acids reduces plasma insulin-like growth factor-I (IGF-I) but does not affect plasma IGF-binding protein-1 in rats
    • Takenaka A, Oki N, Takahashi SI, Noguchi T. (2000). Dietary restriction of single essential amino acids reduces plasma insulin-like growth factor-I (IGF-I) but does not affect plasma IGF-binding protein-1 in rats. J Nutr 130: 2910-2914. (Pubitemid 32005316)
    • (2000) Journal of Nutrition , vol.130 , Issue.12 , pp. 2910-2914
    • Takenaka, A.1    Oki, N.2    Takahashi, S.-I.3    Noguchi, T.4
  • 149
    • 84965810269 scopus 로고
    • The dependence of tumor formation on the composition of the calorie-restricted diet as well as on the degree of restriction
    • Tannenbaum A. (1945). The dependence of tumor formation on the composition of the calorie-restricted diet as well as on the degree of restriction. Cancer Res 5: 616-625.
    • (1945) Cancer Res , vol.5 , pp. 616-625
    • Tannenbaum, A.1
  • 150
    • 0018774739 scopus 로고
    • Effects of prolonged food deprivation on the ultradian growth hormone rhythm and immunoreactive somatostatin tissue levels in the rat
    • Tannenbaum GS, Rorstad O, Brazeau P. (1979). Effects of prolonged food deprivation on the ultradian growth hormone rhythm and immunoreactive somatostatin tissue levels in the rat. Endocrinology 104: 1733-1738. (Pubitemid 9194124)
    • (1979) Endocrinology , vol.104 , Issue.6 , pp. 1733-1738
    • Shaffer Tannenbaum, G.1    Rorstad, O.2    Brazeau, P.3
  • 151
    • 23944507152 scopus 로고    scopus 로고
    • Starvation and oxidative stress resistance in Drosophila are mediated through the eIF4E-binding protein, d4E-BP
    • DOI 10.1101/gad.1311805
    • Tettweiler G, Miron M, Jenkins M, Sonenberg N, Lasko PF. (2005). Starvation and oxidative stress resistance in Drosophila are mediated through the eIF4E-binding protein, d4E-BP. Genes Dev 19: 1840-1843. (Pubitemid 41186983)
    • (2005) Genes and Development , vol.19 , Issue.16 , pp. 1840-1843
    • Tettweiler, G.1    Miron, M.2    Jenkins, M.3    Sonenberg, N.4    Lasko, P.F.5
  • 152
    • 0032835137 scopus 로고    scopus 로고
    • Novel sensing mechanisms and targets for the cAMP-protein kinase A pathway in the yeast Saccharomyces cerevisiae
    • DOI 10.1046/j.1365-2958.1999.01538.x
    • Thevelein JM, de Winde JH. (1999). Novel sensing mechanisms and targets for the cAMP-protein kinase A pathway in the yeast Saccharomyces cerevisiae. Mol Microbiol 33: 904-918. (Pubitemid 29425244)
    • (1999) Molecular Microbiology , vol.33 , Issue.5 , pp. 904-918
    • Thevelein, J.M.1    De Winde, J.H.2
  • 153
    • 0032786770 scopus 로고    scopus 로고
    • Regulation of insulin-like growth factor-I in starvation and injury
    • Thissen JP, Underwood LE, Ketelslegers JM. (1999). Regulation of insulin-like growth factor-I in starvation and injury. Nutr Rev 57: 167-176. (Pubitemid 29357674)
    • (1999) Nutrition Reviews , vol.57 , Issue.6 , pp. 167-176
    • Thissen, J.-P.1    Underwood, L.E.2    Ketelslegers, J.-M.3
  • 154
    • 0014007110 scopus 로고
    • Treatment of obesity by total fasting for up to 249 days
    • Thomson TJ, Runcie J, Miller V. (1966). Treatment of obesity by total fasting for up to 249 days. Lancet 2: 992-996.
    • (1966) Lancet , vol.2 , pp. 992-996
    • Thomson, T.J.1    Runcie, J.2    Miller, V.3
  • 155
    • 0036830917 scopus 로고    scopus 로고
    • Cachexia in cancer patients
    • DOI 10.1038/nrc927
    • Tisdale MJ. (2002). Cachexia in cancer patients. Nat Rev Cancer 2: 862-871. (Pubitemid 37328904)
    • (2002) Nature Reviews Cancer , vol.2 , Issue.11 , pp. 862-871
    • Tisdale, M.J.1
  • 156
    • 0005161085 scopus 로고
    • The effects of total starvation upon the levels of circulating glucagon and insulin in man
    • Unger RH, Eisentraut AM, Madison LL. (1963). The effects of total starvation upon the levels of circulating glucagon and insulin in man. J Clin Invest 42: 1031-1039.
    • (1963) J Clin Invest , vol.42 , pp. 1031-1039
    • Unger, R.H.1    Eisentraut, A.M.2    Madison, L.L.3
  • 159
    • 66249108601 scopus 로고    scopus 로고
    • Understanding the Warburg effect: The metabolic requirements of cell proliferation
    • Vander Heiden MG, Cantley LC, Thompson CB. (2009). Understanding the Warburg effect: the metabolic requirements of cell proliferation. Science 324: 1029-1033.
    • (2009) Science , vol.324 , pp. 1029-1033
    • Vander Heiden, M.G.1    Cantley, L.C.2    Thompson, C.B.3
  • 160
    • 34447288233 scopus 로고    scopus 로고
    • Alternate-day fasting and chronic disease prevention: A review of human and animal trials
    • Varady KA, Hellerstein MK. (2007). Alternate-day fasting and chronic disease prevention: a review of human and animal trials. Am J Clin Nutr 86: 7-13. (Pubitemid 47041587)
    • (2007) American Journal of Clinical Nutrition , vol.86 , Issue.1 , pp. 7-13
    • Varady, K.A.1    Hellerstein, M.K.2
  • 161
    • 57049132739 scopus 로고    scopus 로고
    • Glucose metabolism inhibits apoptosis in neurons and cancer cells by redox inactivation of cytochrome c
    • Vaughn AE, Deshmukh M. (2008). Glucose metabolism inhibits apoptosis in neurons and cancer cells by redox inactivation of cytochrome c. Nat Cell Biol 10: 1477-1483.
    • (2008) Nat Cell Biol , vol.10 , pp. 1477-1483
    • Vaughn, A.E.1    Deshmukh, M.2
  • 162
    • 65549123532 scopus 로고    scopus 로고
    • Strong dietary restrictions protect Drosophila against anoxia/reoxygenation injuries
    • Vigne P, Tauc M, Frelin C. (2009). Strong dietary restrictions protect Drosophila against anoxia/reoxygenation injuries. PLoS One 4: e5422.
    • (2009) PLoS One , vol.4
    • Vigne, P.1    Tauc, M.2    Frelin, C.3
  • 163
    • 4043181214 scopus 로고    scopus 로고
    • Cancer genes and the pathways they control
    • DOI 10.1038/nm1087
    • Vogelstein B, Kinzler KW. (2004). Cancer genes and the pathways they control. Nat Med 10: 789-799. (Pubitemid 39070849)
    • (2004) Nature Medicine , vol.10 , Issue.8 , pp. 789-799
    • Vogelstein, B.1    Kinzler, K.W.2
  • 164
    • 33645988855 scopus 로고    scopus 로고
    • The comparative physiology of food deprivation: From feast to famine
    • Wang T, Hung CC, Randall DJ. (2006). The comparative physiology of food deprivation: from feast to famine. Annu Rev Physiol 68: 223-251.
    • (2006) Annu Rev Physiol , vol.68 , pp. 223-251
    • Wang, T.1    Hung, C.C.2    Randall, D.J.3
  • 165
    • 34648864233 scopus 로고    scopus 로고
    • Age, severe comorbidity and functional impairment independently contribute to poor survival in cancer patients
    • DOI 10.1007/s00432-007-0233-x
    • Wedding U, Rohrig B, Klippstein A, Pientka L, Hoffken K. (2007). Age, severe comorbidity and functional impairment independently contribute to poor survival in cancer patients. J Cancer Res Clin Oncol 133: 945-950. (Pubitemid 47561710)
    • (2007) Journal of Cancer Research and Clinical Oncology , vol.133 , Issue.12 , pp. 945-950
    • Wedding, U.1    Rohrig, B.2    Klippstein, A.3    Pientka, L.4    Hoffken, K.5
  • 166
    • 38949137849 scopus 로고    scopus 로고
    • Life span extension by calorie restriction depends on Rim15 and transcription factors downstream of Ras/PKA and Sch9
    • Tor
    • Wei M, Fabrizio P, Hu J, Ge H, Cheng C, Li L et al. (2008). Life span extension by calorie restriction depends on Rim15 and transcription factors downstream of Ras/PKA, Tor, and Sch9. PLoS Genet 4: e13.
    • (2008) PLoS Genet , vol.4
    • Wei, M.1    Fabrizio, P.2    Hu, J.3    Ge, H.4    Cheng, C.5    Li, L.6
  • 167
    • 67149130284 scopus 로고    scopus 로고
    • Tor 1/Sch9-regulated carbon source substitution is as effective as calorie restriction in life span extension
    • Wei M, Fabrizio P, Madia F, Hu J, Ge H, Li LM et al. (2009). Tor1/Sch9-regulated carbon source substitution is as effective as calorie restriction in life span extension. PLoS Genet 5: e1000467.
    • (2009) PLoS Genet , vol.5
    • Wei, M.1    Fabrizio, P.2    Madia, F.3    Hu, J.4    Ge, H.5    Li, L.M.6
  • 169
    • 0022517746 scopus 로고
    • The retardation of aging in mice by dietary restriction: Longevity, cancer, immunity and lifetime energy intake
    • Weindruch R, Walford RL, Fligiel S, Guthrie D. (1986). The retardation of aging in mice by dietary restriction: longevity, cancer, immunity and lifetime energy intake. J Nutr 116: 641-654. (Pubitemid 16066430)
    • (1986) Journal of Nutrition , vol.116 , Issue.4 , pp. 641-654
    • Weindruch, R.1    Walford, R.L.2    Fligiel, S.3    Guthrie, D.4
  • 170
    • 0020044308 scopus 로고
    • Dietary restriction in mice beginning at 1 year of age: Effect on life-span and spontaneous cancer incidence
    • Weindruch R, Walford RL. (1982). Dietary restriction in mice beginning at 1 year of age: effect on life-span and spontaneous cancer incidence. Science 215: 1415-1418. (Pubitemid 12129729)
    • (1982) Science , vol.215 , Issue.4538 , pp. 1415-1418
    • Weindruch, R.1    Walford, R.L.2
  • 171
    • 33645017887 scopus 로고    scopus 로고
    • Long-term starvation and ageing induce AGE-1/PI 3-kinase-dependent trans-location of DAF-16/FOXO to the cytoplasm
    • Weinkove D, Halstead JR, Gems D, Divecha N. (2006). Long-term starvation and ageing induce AGE-1/PI 3-kinase-dependent trans-location of DAF-16/FOXO to the cytoplasm. BMC Biol 4: 1.
    • (2006) BMC Biol , vol.4 , pp. 1
    • Weinkove, D.1    Halstead, J.R.2    Gems, D.3    Divecha, N.4
  • 174
    • 51849111556 scopus 로고    scopus 로고
    • PI3K pathway alterations in cancer: Variations on a theme
    • Yuan TL, Cantley LC. (2008). PI3K pathway alterations in cancer: variations on a theme. Oncogene 27: 5497-5510.
    • (2008) Oncogene , vol.27 , pp. 5497-5510
    • Yuan, T.L.1    Cantley, L.C.2
  • 175
    • 0029076713 scopus 로고
    • Physiological role of the insulin-like growth factor binding proteins
    • Zapf J. (1995). Physiological role of the insulin-like growth factor binding proteins. Eur J Endocrinol 132: 645-654.
    • (1995) Eur J Endocrinol , vol.132 , pp. 645-654
    • Zapf, J.1
  • 176
    • 77952165770 scopus 로고    scopus 로고
    • Ghrelin O-acyltransferase (GOAT) is essential for growth hormone-mediated
    • Zhao TJ, Liang G, Li RL, Xie X, Sleeman MW, Murphy AJ et al. (2010). Ghrelin O-acyltransferase (GOAT) is essential for growth hormone-mediated survival of calorie-restricted mice. Proc Natl Acad Sci USA 107: 7467-7472.
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 7467-7472
    • Zhao, T.J.1    Liang, G.2    Li, R.L.3    Xie, X.4    Sleeman, M.W.5    Murphy, A.J.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.