-
2
-
-
33646546302
-
Aging of the immune system: How much can the adaptive immune system adapt?
-
Weng, N. P. 2006. Aging of the immune system: how much can the adaptive immune system adapt? Immunity 24: 495-499.
-
(2006)
Immunity
, vol.24
, pp. 495-499
-
-
Weng, N.P.1
-
3
-
-
33744996006
-
Why Aging T Cells Fail: Implications for Vaccination
-
DOI 10.1016/j.immuni.2006.06.003, PII S1074761306002706
-
Haynes, L., and S. L. Swain. 2006. Why aging T cells fail: implications for vaccination. Immunity 24: 663-666. (Pubitemid 43867372)
-
(2006)
Immunity
, vol.24
, Issue.6
, pp. 663-666
-
-
Haynes, L.1
Swain, S.L.2
-
4
-
-
1142275269
-
Age-related changes in lymphocyte development and function
-
Linton, P. J., and K. Dorshkind. 2004. Age-related changes in lymphocyte development and function. Nat. Immunol. 5: 133-139.
-
(2004)
Nat. Immunol.
, vol.5
, pp. 133-139
-
-
Linton, P.J.1
Dorshkind, K.2
-
5
-
-
21044451726
-
The influence of age on T cell generation and TCR diversity
-
Naylor, K., G. Li, A. N. Vallejo, W. W. Lee, K. Koetz, E. Bryl, J. Witkowski, J. Fulbright, C. M. Weyand, and J. J. Goronzy. 2005. The influence of age on T cell generation and TCR diversity. J. Immunol. 174: 7446-7452.
-
(2005)
J. Immunol.
, vol.174
, pp. 7446-7452
-
-
Naylor, K.1
Li, G.2
Vallejo, A.N.3
Lee, W.W.4
Koetz, K.5
Bryl, E.6
Witkowski, J.7
Fulbright, J.8
Weyand, C.M.9
Goronzy, J.J.10
-
7
-
-
23944441502
-
T cell development and receptor diversity during aging
-
Goronzy, J. J., and C. M. Weyand. 2005. T cell development and receptor diversity during aging. Curr. Opin. Immunol. 17: 468-475.
-
(2005)
Curr. Opin. Immunol.
, vol.17
, pp. 468-475
-
-
Goronzy, J.J.1
Weyand, C.M.2
-
8
-
-
43449105029
-
T cell homeostasis
-
Sprent, J., J. H. Cho, O. Boyman, and C. D. Surh. 2008. T cell homeostasis. Immunol. Cell Biol. 86: 312-319.
-
(2008)
Immunol. Cell Biol.
, vol.86
, pp. 312-319
-
-
Sprent, J.1
Cho, J.H.2
Boyman, O.3
Surh, C.D.4
-
9
-
-
23044433753
-
Homeostasis and the age-associated defect of CD4 T cells
-
Swain, S., K. Clise-Dwyer, and L. Haynes. 2005. Homeostasis and the age-associated defect of CD4 T cells. Semin. Immunol. 17: 370-307.
-
(2005)
Semin. Immunol.
, vol.17
, pp. 370-1307
-
-
Swain, S.1
Clise-Dwyer, K.2
Haynes, L.3
-
10
-
-
41149170727
-
Age-associated decline in T cell repertoire diversity leads to holes in the repertoire and impaired immunity to influenza virus
-
Yager, E. J., M. Ahmed, K. Lanzer, T. D. Randall, D. L. Woodland, and M. A. Blackman. 2008. Age-associated decline in T cell repertoire diversity leads to holes in the repertoire and impaired immunity to influenza virus. J. Exp. Med. 205: 711-723.
-
(2008)
J. Exp. Med.
, vol.205
, pp. 711-723
-
-
Yager, E.J.1
Ahmed, M.2
Lanzer, K.3
Randall, T.D.4
Woodland, D.L.5
Blackman, M.A.6
-
11
-
-
46249132015
-
Ageing and life-long maintenance of T-cell subsets in the face of latent persistent infections
-
Nikolich-Zugich, J. 2008. Ageing and life-long maintenance of T-cell subsets in the face of latent persistent infections. Nat. Rev. Immunol. 8: 512-522.
-
(2008)
Nat. Rev. Immunol.
, vol.8
, pp. 512-522
-
-
Nikolich-Zugich, J.1
-
13
-
-
33744826033
-
Thymic output in aged mice
-
Hale, J. S., T. E. Boursalian, G. L. Turk, and P. J. Fink. 2006. Thymic output in aged mice. Proc. Natl. Acad. Sci. USA 103: 8447-8452.
-
(2006)
Proc. Natl. Acad. Sci. USA
, vol.103
, pp. 8447-8452
-
-
Hale, J.S.1
Boursalian, T.E.2
Turk, G.L.3
Fink, P.J.4
-
14
-
-
0036198778
-
T cell receptor excision circle assessment of thymopoiesis in aging mice
-
Sempowski, G. D., M. E. Gooding, H. X. Liao, P. T. Le, and B. F. Haynes. 2002. T cell receptor excision circle assessment of thymopoiesis in aging mice. Mol. Immunol. 38: 841-848.
-
(2002)
Mol. Immunol.
, vol.38
, pp. 841-848
-
-
Sempowski, G.D.1
Gooding, M.E.2
Liao, H.X.3
Le, P.T.4
Haynes, B.F.5
-
15
-
-
0345688661
-
Leptin induces growth hormone secretion from peripheral blood mononuclear cells via a protein kinase C and nitric oxide dependent mechanisms
-
Dixit, V. D., M. Mielenz, D. D. Taub, and N. Parvizi. 2003. Leptin induces growth hormone secretion from peripheral blood mononuclear cells via a protein kinase C and nitric oxide dependent mechanisms. Endocrinology 144: 5595-5603.
-
(2003)
Endocrinology
, vol.144
, pp. 5595-5603
-
-
Dixit, V.D.1
Mielenz, M.2
Taub, D.D.3
Parvizi, N.4
-
16
-
-
54249102288
-
The intricate interface between immune and metabolic regulation: A role for leptin in the pathogenesis of multiple sclerosis?
-
Matarese, G., C. Procaccini, and V. De Rosa. 2008. The intricate interface between immune and metabolic regulation: a role for leptin in the pathogenesis of multiple sclerosis? J. Leukocyte Biol. 84: 893-899.
-
(2008)
J. Leukocyte Biol.
, vol.84
, pp. 893-899
-
-
Matarese, G.1
Procaccini, C.2
De Rosa, V.3
-
17
-
-
33847312289
-
A key role of leptin in the control of regulatory T cell proliferation
-
De Rosa, V., C. Procaccini, G. Calì, G. Pirozzi, S. Fontana, S. Zappacosta, A. La Cava, and G. Matarese. 2007. A key role of leptin in the control of regulatory T cell proliferation. Immunity 26: 241-255.
-
(2007)
Immunity
, vol.26
, pp. 241-255
-
-
De Rosa, V.1
Procaccini, C.2
Calì, G.3
Pirozzi, G.4
Fontana, S.5
Zappacosta, S.6
La Cava, A.7
Matarese, G.8
-
18
-
-
36549042103
-
Adipokines as emerging mediators of immune response and inflammation
-
DOI 10.1038/ncprheum0674, PII NCPRHEUM0674
-
Lago, F., C. Dieguez, J. Gómez-Reino, and O. Gualillo. 2007. Adipokines as emerging mediators of immune response and inflammation. Nat. Clin. Pract. Rheumatol. 3: 716-724. (Pubitemid 350187017)
-
(2007)
Nature Clinical Practice Rheumatology
, vol.3
, Issue.12
, pp. 716-724
-
-
Lago, F.1
Dieguez, C.2
Gomez-Reino, J.3
Gualillo, O.4
-
19
-
-
54249149973
-
Adipose-immune interactions during obesity and caloric restriction: Reciprocal mechanisms regulating immunity and health span
-
Dixit, V. D. 2008. Adipose-immune interactions during obesity and caloric restriction: reciprocal mechanisms regulating immunity and health span. J. Leukocyte Biol. 84: 882-892.
-
(2008)
J. Leukocyte Biol.
, vol.84
, pp. 882-892
-
-
Dixit, V.D.1
-
20
-
-
3242749843
-
Ghrelin inhibits leptin- And activation-induced proinflammatory cytokine expression by human monocytes and T cells
-
Dixit, V. D., E. M. Schaffer, R. S. Pyle, G. D. Collins, S. K. Sakthivel, R. Palaniappan, J. W. Lillard, Jr., and D. D. Taub. 2004. Ghrelin inhibits leptin- and activation-induced proinflammatory cytokine expression by human monocytes and T cells. J. Clin. Invest. 114: 57-66.
-
(2004)
J. Clin. Invest.
, vol.114
, pp. 57-66
-
-
Dixit, V.D.1
Schaffer, E.M.2
Pyle, R.S.3
Collins, G.D.4
Sakthivel, S.K.5
Palaniappan, R.6
Lillard Jr., J.W.7
Taub, D.D.8
-
21
-
-
34948853362
-
Ghrelin promotes thymopoiesis during aging
-
Dixit, V. D., H. Yang, Y. Sun, A. T. Weeraratna, Y. H. Youm, R. G. Smith, and D. D. Taub. 2007. Ghrelin promotes thymopoiesis during aging. J. Clin. Invest. 117: 2778-2790.
-
(2007)
J. Clin. Invest.
, vol.117
, pp. 2778-2790
-
-
Dixit, V.D.1
Yang, H.2
Sun, Y.3
Weeraratna, A.T.4
Youm, Y.H.5
Smith, R.G.6
Taub, D.D.7
-
22
-
-
65449128145
-
Deficient ghrelin receptor mediated signaling compromises thymic stromal cell microenvironment by accelerating thymic adiposity
-
Youm, Y. H., H. Yang, Y. Sun, R. G. Smith, N. R. Manley, B. Vandanmagsar, and V. D. Dixit. 2009. Deficient ghrelin receptor mediated signaling compromises thymic stromal cell microenvironment by accelerating thymic adiposity. J. Biol. Chem. 284: 7068-7077.
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 7068-7077
-
-
Youm, Y.H.1
Yang, H.2
Sun, Y.3
Smith, R.G.4
Manley, N.R.5
Vandanmagsar, B.6
Dixit, V.D.7
-
23
-
-
0348047391
-
The retardation of aging by caloric restriction: Its significance in the transgenic era
-
Barger, J. L., R. L. Walford, and R. Weindruch. 2003. The retardation of aging by caloric restriction: its significance in the transgenic era. Exp. Gerontol. 38: 1343-1351.
-
(2003)
Exp. Gerontol.
, vol.38
, pp. 1343-1351
-
-
Barger, J.L.1
Walford, R.L.2
Weindruch, R.3
-
24
-
-
35348972430
-
Genetic links between diet and lifespan: Shared mechanisms from yeast to humans
-
Bishop, N. A., and L. Guarente. 2007. Genetic links between diet and lifespan: shared mechanisms from yeast to humans. Nat. Rev. Genet. 8: 835-844.
-
(2007)
Nat. Rev. Genet.
, vol.8
, pp. 835-844
-
-
Bishop, N.A.1
Guarente, L.2
-
25
-
-
27544454697
-
Mice and flies and monkeys too: Caloric restriction rejuvenates the aging immune system of non-human primates
-
Nikolich-Zugich, J., and I. Messaoudi. 2005. Mice and flies and monkeys too: caloric restriction rejuvenates the aging immune system of non-human primates. Exp. Gerontol. 40: 884-893.
-
(2005)
Exp. Gerontol.
, vol.40
, pp. 884-893
-
-
Nikolich-Zugich, J.1
Messaoudi, I.2
-
26
-
-
34548689861
-
Chronic caloric restriction induces forestomach hypertrophy with enhanced ghrelin levels during aging
-
Yang, H., Y. H. Youm, C. Nakata, and V. D. Dixit. 2007. Chronic caloric restriction induces forestomach hypertrophy with enhanced ghrelin levels during aging. Peptides 10: 1931-1936.
-
(2007)
Peptides
, vol.10
, pp. 1931-1936
-
-
Yang, H.1
Youm, Y.H.2
Nakata, C.3
Dixit, V.D.4
-
27
-
-
0022585737
-
Changes in human thymus during aging
-
Steinmann, G. G. 1986. Changes in human thymus during aging. Curr. Top. Pathol. 75: 43-88.
-
(1986)
Curr. Top. Pathol.
, vol.75
, pp. 43-88
-
-
Steinmann, G.G.1
-
28
-
-
0032718690
-
Analysis of the human thymic perivascular space during aging
-
Flores, K. G., J. Li, G. D. Sempowski, B. F. Haynes, and L. P. Hale. 1999. Analysis of the human thymic perivascular space during aging. J. Clin. Invest. 104: 1031-1039.
-
(1999)
J. Clin. Invest.
, vol.104
, pp. 1031-1039
-
-
Flores, K.G.1
Li, J.2
Sempowski, G.D.3
Haynes, B.F.4
Hale, L.P.5
-
29
-
-
2942700206
-
Reduction in the developmental potential of intrathymic T cell progenitors with age
-
Min, H., E. Montecino-Rodriguez, and K. Dorshkind. 2004. Reduction in the developmental potential of intrathymic T cell progenitors with age. J. Immunol. 173: 245-250. (Pubitemid 38797348)
-
(2004)
Journal of Immunology
, vol.173
, Issue.1
, pp. 245-250
-
-
Min, H.1
Montecino-Rodriguez, E.2
Dorshkind, K.3
-
30
-
-
33644842282
-
From stem cell to T cell: One route or many?
-
Bhandoola, A., and A. Sambandam. 2006. From stem cell to T cell: one route or many? Nat. Rev. Immunol. 6: 117-126.
-
(2006)
Nat. Rev. Immunol.
, vol.6
, pp. 117-126
-
-
Bhandoola, A.1
Sambandam, A.2
-
31
-
-
33745210354
-
Ghrelin and the growth hormone secretagogue receptor constitute a novel autocrine pathway in astrocytoma motility
-
Dixit, V. D., A. T. Weeraratna, H. Yang, D. Bertak, A. Cooper-Jenkins, G. J. Riggins, C. G. Eberhart, and D. D. Taub. 2006. Ghrelin and the growth hormone secretagogue receptor constitute a novel autocrine pathway in astrocytoma motility. J. Biol. Chem. 281: 16681-16690.
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 16681-16690
-
-
Dixit, V.D.1
Weeraratna, A.T.2
Yang, H.3
Bertak, D.4
Cooper-Jenkins, A.5
Riggins, G.J.6
Eberhart, C.G.7
Taub, D.D.8
-
32
-
-
37049010471
-
Unbiased analysis, enrichment and purification of thymic stromal cells
-
Gray, D. H., A. L. Fletcher, M. Hammett, N. Seach, T. Ueno, L. F. Young, J. Barbuto, R. L. Boyd, and A. P. Chidgey. 2008. Unbiased analysis, enrichment and purification of thymic stromal cells. J. Immunol. Methods 329: 56-66.
-
(2008)
J. Immunol. Methods
, vol.329
, pp. 56-66
-
-
Gray, D.H.1
Fletcher, A.L.2
Hammett, M.3
Seach, N.4
Ueno, T.5
Young, L.F.6
Barbuto, J.7
Boyd, R.L.8
Chidgey, A.P.9
-
33
-
-
0036916440
-
Induction of T cell development from hematopoietic progenitor cells by Delta-like-1 in vitro
-
Schmitt, T. M., and J. C. Zuniga-Pflucker. 2002. Induction of T cell development from hematopoietic progenitor cells by Delta-like-1 in vitro. Immunity 17: 749-756.
-
(2002)
Immunity
, vol.17
, pp. 749-756
-
-
Schmitt, T.M.1
Zuniga-Pflucker, J.C.2
-
34
-
-
0027251463
-
The sizes of the CDR3 hypervariable regions of the murine T-cell receptor β chains vary as a function of the recombined germ-line segments
-
Pannetier, C., M. Cochet, S. Darche, A. Casrouge, M. Zöller, and P. Kourilsky. 1993. The sizes of the CDR3 hypervariable regions of the murine T-cell receptor β chains vary as a function of the recombined germ-line segments. Proc. Natl. Acad. Sci. USA 90: 4319-4323.
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 4319-4323
-
-
Pannetier, C.1
Cochet, M.2
Darche, S.3
Casrouge, A.4
Zöller, M.5
Kourilsky, P.6
-
36
-
-
33845898766
-
Delay of T cell senescence by caloric restriction in aged long-lived nonhuman primates
-
Messaoudi, I., J. Warner, M. Fischer, B. Park, B. Hill, J. Mattison, M. A. Lane, G. S. Roth, D. K. Ingram, L. J. Picker, et al. 2006. Delay of T cell senescence by caloric restriction in aged long-lived nonhuman primates. Proc. Natl. Acad. Sci. USA 103: 19448-19453.
-
(2006)
Proc. Natl. Acad. Sci. USA
, vol.103
, pp. 19448-19453
-
-
Messaoudi, I.1
Warner, J.2
Fischer, M.3
Park, B.4
Hill, B.5
Mattison, J.6
Lane, M.A.7
Roth, G.S.8
Ingram, D.K.9
Picker, L.J.10
-
37
-
-
34247170523
-
A unique thymic fibroblast population revealed by the monoclonal antibody MTS-15
-
Gray, D. H., D. Tull, T. Ueno, N. Seach, B. J. Classon, A. Chidgey, M. J. McConville, and R. L. Boyd. 2007. A unique thymic fibroblast population revealed by the monoclonal antibody MTS-15. J. Immunol 178: 4956-4965.
-
(2007)
J. Immunol
, vol.178
, pp. 4956-4965
-
-
Gray, D.H.1
Tull, D.2
Ueno, T.3
Seach, N.4
Classon, B.J.5
Chidgey, A.6
McConville, M.J.7
Boyd, R.L.8
-
38
-
-
33845239216
-
Developmental kinetics, turnover, and stimulatory capacity of thymic epithelial cells
-
Gray, D. H., N. Seach, T. Ueno, M. K. Milton, A. Liston, A. M. Lew, C. C. Goodnow, and R. L. Boyd. 2006. Developmental kinetics, turnover, and stimulatory capacity of thymic epithelial cells. Blood 108: 3777-3785.
-
(2006)
Blood
, vol.108
, pp. 3777-3785
-
-
Gray, D.H.1
Seach, N.2
Ueno, T.3
Milton, M.K.4
Liston, A.5
Lew, A.M.6
Goodnow, C.C.7
Boyd, R.L.8
-
39
-
-
40549126634
-
Architectural changes in the thymus of aging mice
-
Aw, D., A. B. Silva, M. Maddick, T. von Zglinicki, and D. B. Palmer. 2008. Architectural changes in the thymus of aging mice. Aging Cell 7: 158-167.
-
(2008)
Aging Cell
, vol.7
, pp. 158-167
-
-
Aw, D.1
Silva, A.B.2
Maddick, M.3
Von Zglinicki, T.4
Palmer, D.B.5
-
40
-
-
67149098203
-
Axin expression in thymic stromal cells contributes to age-related increase in thymic adiposity and associated with reduced thymopoiesis independently of ghrelin signaling
-
Yang, H., Y. H. Youm, J. S. Rim, C. Galban, B. Vandanmagsar, and V. D. Dixit. 2009. Axin expression in thymic stromal cells contributes to age-related increase in thymic adiposity and associated with reduced thymopoiesis independently of ghrelin signaling. J. Leukocyte Biol. 85: 928-938.
-
(2009)
J. Leukocyte Biol.
, vol.85
, pp. 928-938
-
-
Yang, H.1
Youm, Y.H.2
Rim, J.S.3
Galban, C.4
Vandanmagsar, B.5
Dixit, V.D.6
-
41
-
-
33947192136
-
Sustained thymopoiesis and improvement in functional immunity induced by exogenous KGF administration in murine models of aging
-
Min, D., A. Panoskaltsis-Mortari, M. Kuro-O, G. A. Holländer, B. R. Blazar, and K. I. Weinberg. 2007. Sustained thymopoiesis and improvement in functional immunity induced by exogenous KGF administration in murine models of aging. Blood 109: 2529-2537.
-
(2007)
Blood
, vol.109
, pp. 2529-2537
-
-
Min, D.1
Panoskaltsis-Mortari, A.2
Kuro-O, M.3
Holländer, G.A.4
Blazar, B.R.5
Weinberg, K.I.6
-
42
-
-
34250212481
-
Commitment and developmental potential of extrathymic and intrathymic T cell precursors: Plenty to choose from
-
Bhandoola, A., H. von Boehmer, H. T. Petrie, and J. C. Zuniga-Pflucker. 2007. Commitment and developmental potential of extrathymic and intrathymic T cell precursors: plenty to choose from. Immunity 26: 678-689.
-
(2007)
Immunity
, vol.26
, pp. 678-689
-
-
Bhandoola, A.1
Von Boehmer, H.2
Petrie, H.T.3
Zuniga-Pflucker, J.C.4
-
43
-
-
34247882592
-
Zoned out: Functional mapping of stromal signaling microenvironments in the thymus
-
Petrie, H. T., and J. C. Zuniga-Pflucker. 2007. Zoned out: functional mapping of stromal signaling microenvironments in the thymus. Annu. Rev. Immunol. 25: 649-679.
-
(2007)
Annu. Rev. Immunol.
, vol.25
, pp. 649-679
-
-
Petrie, H.T.1
Zuniga-Pflucker, J.C.2
-
44
-
-
0142149043
-
Critical Role for CXCR4 Signaling in Progenitor Localization and T Cell Differentiation in the Postnatal Thymus
-
Plotkin, J., S. E. Prockop, A. Lepique, and H. T. Petrie. 2003. Critical role for CXCR4 signaling in progenitor localization and T cell differentiation in the post-natal thymus. J. Immunol. 171: 4521-4527. (Pubitemid 37310567)
-
(2003)
Journal of Immunology
, vol.171
, Issue.9
, pp. 4521-4527
-
-
Plotkin, J.1
Prockop, S.E.2
Lepique, A.3
Petrie, H.T.4
-
45
-
-
54049125342
-
CCL25 increases thymopoiesis after androgen withdrawal
-
Williams, K. M., P. J. Lucas, C. V. Bare, J. Wang, Y. W. Chu, E. Tayler, V. Kapoor, and R. E. Gress. 2008. CCL25 increases thymopoiesis after androgen withdrawal. Blood 112: 3255-3263.
-
(2008)
Blood
, vol.112
, pp. 3255-3263
-
-
Williams, K.M.1
Lucas, P.J.2
Bare, C.V.3
Wang, J.4
Chu, Y.W.5
Tayler, E.6
Kapoor, V.7
Gress, R.E.8
-
46
-
-
34547895468
-
Chemokine receptor expression defines heterogeneity in the earliest thymic migrants
-
Jenkinson, W. E., S. W. Rossi, S. M. Parnell, W. W. Agace, Y. Takahama, E. J. Jenkinson, and G. Anderson. 2007. Chemokine receptor expression defines heterogeneity in the earliest thymic migrants. Eur. J. Immunol. 37: 2090-2096.
-
(2007)
Eur. J. Immunol.
, vol.37
, pp. 2090-2096
-
-
Jenkinson, W.E.1
Rossi, S.W.2
Parnell, S.M.3
Agace, W.W.4
Takahama, Y.5
Jenkinson, E.J.6
Anderson, G.7
-
47
-
-
33845325476
-
Adipocyte differentiation from the inside out
-
Rosen, E. D., and O. A. MacDougald. 2006. Adipocyte differentiation from the inside out. Nat. Rev. Mol. Cell Biol. 7: 885-896.
-
(2006)
Nat. Rev. Mol. Cell Biol.
, vol.7
, pp. 885-896
-
-
Rosen, E.D.1
MacDougald, O.A.2
-
48
-
-
0028641559
-
Stimulation of adipogenesis in fibroblasts by PPARγ2, a lipid-activated transcription factor
-
Tontonoz, P., E. Hu, and B. M. Spiegelman. 1994. Stimulation of adipogenesis in fibroblasts by PPARγ2, a lipid-activated transcription factor. Cell 79: 1147-1156.
-
(1994)
Cell
, vol.79
, pp. 1147-1156
-
-
Tontonoz, P.1
Hu, E.2
Spiegelman, B.M.3
-
49
-
-
1942518840
-
PPARs and the complex journey to obesity
-
Evans, R., G. D. Barish, and Y. X. Wang. 2004. PPARs and the complex journey to obesity. Nat. Med. 10: 1-7.
-
(2004)
Nat. Med.
, vol.10
, pp. 1-7
-
-
Evans, R.1
Barish, G.D.2
Wang, Y.X.3
-
50
-
-
33846684242
-
Xanthine oxidoreductase is a regulator of adipogenesis and PPARγ activity
-
Cheung, K. J., I. Tzameli, P. Pissios, I. Rovira, O. Gavrilova, T. Ohtsubo, Z. Chen, T. Finkel, J. S. Flier, and J. M. Friedman. 2007. Xanthine oxidoreductase is a regulator of adipogenesis and PPARγ activity. Cell. Metab. 5: 115-128.
-
(2007)
Cell. Metab.
, vol.5
, pp. 115-128
-
-
Cheung, K.J.1
Tzameli, I.2
Pissios, P.3
Rovira, I.4
Gavrilova, O.5
Ohtsubo, T.6
Chen, Z.7
Finkel, T.8
Flier, J.S.9
Friedman, J.M.10
-
51
-
-
30744465918
-
Cutting edge: Three-dimensional architecture of the thymus is required to maintain delta-like expression necessary for inducing T cell development
-
Mohtashami, M., and J. C. Zuniga-Pflucker. 2006. Cutting edge: Three-dimensional architecture of the thymus is required to maintain Delta-like expression necessary for inducing T cell development. J. Immunol. 176: 730-734. (Pubitemid 43099668)
-
(2006)
Journal of Immunology
, vol.176
, Issue.2
, pp. 730-734
-
-
Mohtashami, M.1
Zuniga-Pflucker, J.C.2
-
52
-
-
0029791412
-
PPARα and PPARγ activators direct a distinct tissue-specific transcriptional response via a PPRE in the lipoprotein lipase gene
-
Schoonjans, K., J. Peinado-Onsurbe, A. M. Lefebvre, R. A. Heyman, M. Briggs, S. Deeb, B. Staels, and J. Auwerx. 1996. PPARα and PPARγ activators direct a distinct tissue-specific transcriptional response via a PPRE in the lipoprotein lipase gene. EMBO J. 15: 5336-5348.
-
(1996)
EMBO J.
, vol.15
, pp. 5336-5348
-
-
Schoonjans, K.1
Peinado-Onsurbe, J.2
Lefebvre, A.M.3
Heyman, R.A.4
Briggs, M.5
Deeb, S.6
Staels, B.7
Auwerx, J.8
-
53
-
-
0028988487
-
PPARγ2 regulates adipose expression of the phosphoenolpyruvate carboxykinase gene
-
Tontonoz, P., E. Hu, J. Devine, E. G. Beale, and B. M. Spiegelman. 1995. PPARγ2 regulates adipose expression of the phosphoenolpyruvate carboxykinase gene. Mol. Cell. Biol. 15: 351-357.
-
(1995)
Mol. Cell. Biol.
, vol.15
, pp. 351-357
-
-
Tontonoz, P.1
Hu, E.2
Devine, J.3
Beale, E.G.4
Spiegelman, B.M.5
-
54
-
-
0031907427
-
+ repertoire during antiviral therapy
-
+ repertoire during antiviral therapy. Nat. Med. 4: 215-221.
-
(1998)
Nat. Med.
, vol.4
, pp. 215-221
-
-
Gorochov, G.1
Neumann, A.U.2
Kereveur, A.3
Parizot, C.4
Li, T.5
Katlama, C.6
Karmochkine, M.7
Raguin, G.8
Autran, B.9
Debré, P.10
-
55
-
-
0030929766
-
Calorie restriction inhibits the age-related dysregulation of the cytokines TNF-α and IL-6 in C3B10RF1 mice
-
Spaulding, C. C., R. L. Walford, and R. B. Effros. 1997. Calorie restriction inhibits the age-related dysregulation of the cytokines TNF-α and IL-6 in C3B10RF1 mice. Mech. Ageing Dev. 93: 87-94.
-
(1997)
Mech. Ageing Dev.
, vol.93
, pp. 87-94
-
-
Spaulding, C.C.1
Walford, R.L.2
Effros, R.B.3
-
56
-
-
0030990963
-
The accumulation of non-replicative, non-functional, senescent T cells with age is avoided in calorically restricted mice by an enhancement of T cell apoptosis
-
Spaulding, C. C., R. L. Walford, and R. B. Effros. 1997. The accumulation of non-replicative, non-functional, senescent T cells with age is avoided in calorically restricted mice by an enhancement of T cell apoptosis. Mech. Ageing Dev. 93: 25-33.
-
(1997)
Mech. Ageing Dev.
, vol.93
, pp. 25-33
-
-
Spaulding, C.C.1
Walford, R.L.2
Effros, R.B.3
-
57
-
-
0343183281
-
Stepwise development of thymic microenvironments in vivo is regulated by thymocyte subsets
-
van Ewijk, W., G. Holländer, C. Terhorst, and B. Wang. 2000. Stepwise development of thymic microenvironments in vivo is regulated by thymocyte subsets. Development 127: 1583-1591.
-
(2000)
Development
, vol.127
, pp. 1583-1591
-
-
Van Ewijk, W.1
Holländer, G.2
Terhorst, C.3
Wang, B.4
-
58
-
-
0030890694
-
Early αβ T cell development in the thymus of normal and genetically altered mice
-
Fehling, H. J., and H. von Boehmer. 1997. Early αβ T cell development in the thymus of normal and genetically altered mice. Curr. Opin. Immunol. 9: 263-275.
-
(1997)
Curr. Opin. Immunol.
, vol.9
, pp. 263-275
-
-
Fehling, H.J.1
Von Boehmer, H.2
-
59
-
-
0031466862
-
An interleukin-2 receptor γ chain mutation with normal thymus morphology
-
Sharfe, N., M. Shahar, and C. M. Roifman. 1997. An interleukin-2 receptor γ chain mutation with normal thymus morphology. J. Clin. Invest. 100: 3036-3043. (Pubitemid 28022841)
-
(1997)
Journal of Clinical Investigation
, vol.100
, Issue.12
, pp. 3036-3043
-
-
Sharfe, N.1
Shahar, M.2
Roifman, C.M.3
-
60
-
-
13344282747
-
Modulation of hematopoiesis in mice with a truncated mutant of the interleukin-2 receptor gamma chain
-
Ohbo, K., T. Suda, M. Hashiyama, A. Mantani, M. Ikebe, K. Miyakawa, M. Moriyama, M. Nakamura, M. Katsuki, K. Takahashi, K. Yamamura, and K. Sugamura. 1996. Modulation of hematopoiesis in mice with a truncated mutant of the interleukin-2 receptor gamma chain. Blood 87: 956-967.
-
(1996)
Blood
, vol.87
, pp. 956-967
-
-
Ohbo, K.1
Suda, T.2
Hashiyama, M.3
Mantani, A.4
Ikebe, M.5
Miyakawa, K.6
Moriyama, M.7
Nakamura, M.8
Katsuki, M.9
Takahashi, K.10
Yamamura, K.11
Sugamura, K.12
-
61
-
-
34249908901
-
In vitro reprogramming of fibroblasts into a pluripotent ES-cell-like state
-
DOI 10.1038/nature05944, PII NATURE05944
-
Wernig, M., A. Meissner, R. Foreman, T. Brambrink, M. Ku, K. Hochedlinger, B. E. Bernstein, and R. Jaenisch. 2007. In vitro reprogramming of fibroblasts into a pluripotent ES-cell-like state. Nature 448: 318-324. (Pubitemid 47080337)
-
(2007)
Nature
, vol.448
, Issue.7151
, pp. 318-324
-
-
Wernig, M.1
Meissner, A.2
Foreman, R.3
Brambrink, T.4
Ku, M.5
Hochedlinger, K.6
Bernstein, B.E.7
Jaenisch, R.8
-
62
-
-
33644856005
-
Obesity and the role of adipose tissue in inflammation and metabolism
-
Greenberg, A. S., and M. S. Obin. 2006. Obesity and the role of adipose tissue in inflammation and metabolism. Am. J. Clin. Nutr. 83: 461-465.
-
(2006)
Am. J. Clin. Nutr.
, vol.83
, pp. 461-465
-
-
Greenberg, A.S.1
Obin, M.S.2
-
63
-
-
43049165453
-
The epithelial-mesenchymal transition generates cells with properties of stem cells
-
Mani, S. A., W. Guo, M. J. Liao, E. N. Eaton, A. Ayyanan, A. Y. Zhou, M. Brooks, F. Reinhard, C. C. Zhang, M. Shipitsin, et al. 2008. The epithelial-mesenchymal transition generates cells with properties of stem cells. Cell 16: 704-715.
-
(2008)
Cell
, vol.16
, pp. 704-715
-
-
Mani, S.A.1
Guo, W.2
Liao, M.J.3
Eaton, E.N.4
Ayyanan, A.5
Zhou, A.Y.6
Brooks, M.7
Reinhard, F.8
Zhang, C.C.9
Shipitsin, M.10
-
64
-
-
23044433753
-
Homeostasis and the age-associated defect of CD4 T cells
-
Swain, S., K. Clise-Dwyer, and L. Haynes. 2005. Homeostasis and the age-associated defect of CD4 T cells. Semin. Immunol. 17: 370-377.
-
(2005)
Semin. Immunol.
, vol.17
, pp. 370-377
-
-
Swain, S.1
Clise-Dwyer, K.2
Haynes, L.3
-
65
-
-
0019402106
-
Lymphokines and aging: Interleukin-2 production and activity in aged animals
-
Thoman, M. L., and W. O. Weigle. 1981. Lymphokines and aging: interleukin-2 production and activity in aged animals. J. Immunol. 127: 2102-2106.
-
(1981)
J. Immunol.
, vol.127
, pp. 2102-2106
-
-
Thoman, M.L.1
Weigle, W.O.2
-
66
-
-
0023950743
-
Decreased proliferation, interleukin 2 synthesis, and interleukin 2 receptor expression are accompanied by decreased mRNA expression in phytohemagglutinin-stimulated cells from elderly donors
-
Nagel, J. E., R. K. Chopra, F. J. Chrest, M. T. McCoy, E. L. Schneider, N. J. Holbrook, and W. H. Adler. 1988. Decreased proliferation, interleukin 2 synthesis, and interleukin 2 receptor expression are accompanied by decreased mRNA expression in phytohemagglutinin-stimulated cells from elderly donors. J. Clin. Invest. 81: 1096-1102.
-
(1988)
J. Clin. Invest.
, vol.81
, pp. 1096-1102
-
-
Nagel, J.E.1
Chopra, R.K.2
Chrest, F.J.3
McCoy, M.T.4
Schneider, E.L.5
Holbrook, N.J.6
Adler, W.H.7
-
67
-
-
0035478646
-
Vitamin E-enhanced IL-2 production in old mice: Naive but not memory T cells show increased cell division cycling and IL-2-producing capacity
-
Adolfsson, O., B. T. Huber, and S. N. Meydani. 2001. Vitamin E-enhanced IL-2 production in old mice: naive but not memory T cells show increased cell division cycling and IL-2-producing capacity. J. Immunol. 167: 3809-3817. (Pubitemid 32910826)
-
(2001)
Journal of Immunology
, vol.167
, Issue.7
, pp. 3809-3817
-
-
Adolfsson, O.1
Huber, B.T.2
Meydani, S.N.3
-
68
-
-
33646391499
-
Malnutrition and energy restriction differentially affect viral immunity
-
Ritz, B. W., and E. M. Gardner. 2006. Malnutrition and energy restriction differentially affect viral immunity. J. Nutr. 136: 1141-1144.
-
(2006)
J. Nutr.
, vol.136
, pp. 1141-1144
-
-
Ritz, B.W.1
Gardner, E.M.2
|