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Volumn 70, Issue 12, 2015, Pages 1542-1547

Frailty, inflammation, and mortality among persons aging with HIV infection and injection drug use

Author keywords

Frailty; HIV; Inflammation; Injection drug use; Mortality

Indexed keywords

IL6 PROTEIN, HUMAN; INTERLEUKIN 6; TUMOR NECROSIS FACTOR RECEPTOR 1;

EID: 84959357498     PISSN: 10795006     EISSN: 1758535X     Source Type: Journal    
DOI: 10.1093/gerona/glv107     Document Type: Article
Times cited : (76)

References (46)
  • 1
    • 84864276304 scopus 로고    scopus 로고
    • HIV and aging: State of knowledge and areas of critical need for research. A report to the NIH Offce of AIDS Research by the HIV and Aging Working Group
    • High KP, Brennan-Ing M, Clifford DB, et al. HIV and aging: state of knowledge and areas of critical need for research. A report to the NIH Offce of AIDS Research by the HIV and Aging Working Group. J Acquir Immune Defc Syndr. 2012;60(suppl 1):S1-S18. doi:10.1097/QAI.0b013e31825a3668
    • (2012) J Acquir Immune Defc Syndr. , vol.60 , pp. S1-S18
    • High, K.P.1    Brennan-Ing, M.2    Clifford, D.B.3
  • 2
    • 84859379015 scopus 로고    scopus 로고
    • HIV and aging-preparing for the challenges ahead
    • Mills EJ, Bärnighausen T, Negin J. HIV and aging-preparing for the challenges ahead. N Engl J Med. 2012;366:1270-1273. doi:10.1056/NEJMp1113643
    • (2012) N Engl J Med. , vol.366 , pp. 1270-1273
    • Mills, E.J.1    Bärnighausen, T.2    Negin, J.3
  • 3
    • 84902283746 scopus 로고    scopus 로고
    • Biologic aging, frailty, and age-related disease in chronic HIV infection
    • Brothers TD, Rockwood K. Biologic aging, frailty, and age-related disease in chronic HIV infection. Curr Opin HIV AIDS. 2014;9:412-418. doi:10.1097/COH.0000000000000070
    • (2014) Curr Opin HIV AIDS. , vol.9 , pp. 412-418
    • Brothers, T.D.1    Rockwood, K.2
  • 4
    • 80755123417 scopus 로고    scopus 로고
    • Premature age-related comorbidities among HIV-infected persons compared with the general population
    • Guaraldi G, Orlando G, Zona S, et al. Premature age-related comorbidities among HIV-infected persons compared with the general population. Clin Infect Dis. 2011;53:1120-1126. doi:10.1093/cid/cir627
    • (2011) Clin Infect Dis. , vol.53 , pp. 1120-1126
    • Guaraldi, G.1    Orlando, G.2    Zona, S.3
  • 5
    • 81855191203 scopus 로고    scopus 로고
    • HIV infection, immune suppression, and uncontrolled viremia are associated with increased multimorbidity among aging injection drug users
    • Salter ML, Lau B, Go VF, Mehta SH, Kirk GD. HIV infection, immune suppression, and uncontrolled viremia are associated with increased multimorbidity among aging injection drug users. Clin Infect Dis. 2011;53:1256-1264. doi:10.1093/cid/cir673
    • (2011) Clin Infect Dis. , vol.53 , pp. 1256-1264
    • Salter, M.L.1    Lau, B.2    Go, V.F.3    Mehta, S.H.4    Kirk, G.D.5
  • 6
    • 84893164523 scopus 로고    scopus 로고
    • Closing the gap: Increases in life expectancy among treated HIV-positive individuals in the United States and Canada
    • Samji H, Cescon A, Hogg RS, et al. Closing the gap: increases in life expectancy among treated HIV-positive individuals in the United States and Canada. PLoS One. 2013;8:e81355. doi:10.1371/journal.pone.0081355
    • (2013) PLoS One. , vol.8 , pp. e81355
    • Samji, H.1    Cescon, A.2    Hogg, R.S.3
  • 7
    • 1642329318 scopus 로고    scopus 로고
    • Untangling the concepts of disability, frailty, and comorbidity: Implications for improved targeting and care
    • Fried LP, Ferrucci L, Darer J, Williamson JD, Anderson G. Untangling the concepts of disability, frailty, and comorbidity: implications for improved targeting and care. J Gerontol A Biol Sci Med Sci. 2004;59:M255-M263. doi:10.1093/gerona/59.3.M255
    • (2004) J Gerontol A Biol Sci Med Sci. , vol.59 , pp. M255-M263
    • Fried, L.P.1    Ferrucci, L.2    Darer, J.3    Williamson, J.D.4    Anderson, G.5
  • 8
    • 78549256405 scopus 로고    scopus 로고
    • The frailty syndrome: Defnition and natural history
    • Xue QL. The frailty syndrome: defnition and natural history. Clin Geriatr Med. 2011;27:1-15. doi:10.1016/j.cger.2010.08.009
    • (2011) Clin Geriatr Med. , vol.27 , pp. 1-15
    • Xue, Q.L.1
  • 9
    • 33646014444 scopus 로고    scopus 로고
    • Phenotype of frailty: Characterization in the women's health and aging studies
    • Bandeen-Roche K, Xue QL, Ferrucci L, et al. Phenotype of frailty: characterization in the women's health and aging studies. J Gerontol A Biol Sci Med Sci. 2006;61:262-266.
    • (2006) J Gerontol A Biol Sci Med Sci. , vol.61 , pp. 262-266
    • Bandeen-Roche, K.1    Xue, Q.L.2    Ferrucci, L.3
  • 10
    • 2442699834 scopus 로고    scopus 로고
    • Frailty in older adults: Evidence for a phenotype
    • Fried L P, Tangen CM, Walston J, et al. Frailty in older adults: evidence for a phenotype. J Gerontol A Biol Sci Med Sci. 2001;56:M146-M157. doi:10.1093/gerona/56.3.M146
    • (2001) J Gerontol A Biol Sci Med Sci. , vol.56 , pp. M146-M157
    • Fried, L.P.1    Tangen, C.M.2    Walston, J.3
  • 11
    • 84896743037 scopus 로고    scopus 로고
    • Age, comorbidities, and AIDS predict a frailty phenotype in men who have sex with men
    • Althoff KN, Jacobson LP, Cranston RD, et al. Age, comorbidities, and AIDS predict a frailty phenotype in men who have sex with men. J Geron-tol A Biol Sci Med Sci. 2014;69:189-198. doi:10.1093/gerona/glt148
    • (2014) J Geron-tol A Biol Sci Med Sci. , vol.69 , pp. 189-198
    • Althoff, K.N.1    Jacobson, L.P.2    Cranston, R.D.3
  • 12
    • 37349061324 scopus 로고    scopus 로고
    • HIV-1 infection is associated with an earlier occurrence of a phenotype related to frailty
    • Desquilbet L, Jacobson LP, Fried L P, et al. HIV-1 infection is associated with an earlier occurrence of a phenotype related to frailty. J Gerontol A Biol Sci Med Sci. 2007;62:1279-1286.
    • (2007) J Gerontol A Biol Sci Med Sci. , vol.62 , pp. 1279-1286
    • Desquilbet, L.1    Jacobson, L.P.2    Fried, L.P.3
  • 13
    • 84870618535 scopus 로고    scopus 로고
    • Comparison of functional status instruments in HIV-infected adults on effective antiretroviral therapy
    • Erlandson KM, Allshouse AA, Jankowski CM, et al. Comparison of functional status instruments in HIV-infected adults on effective antiretroviral therapy. HIV Clin Trials. 2012;13:324-334. doi:10.1310/hct1306-324
    • (2012) HIV Clin Trials. , vol.13 , pp. 324-334
    • Erlandson, K.M.1    Allshouse, A.A.2    Jankowski, C.M.3
  • 14
    • 84879128554 scopus 로고    scopus 로고
    • Frailty as a novel predictor of mortality and hospitalization in individuals of all ages undergoing hemodialysis
    • McAdams-DeMarco MA, Law A, Salter ML, et al. Frailty as a novel predictor of mortality and hospitalization in individuals of all ages undergoing hemodialysis. J Am Geriatr Soc. 2013;61:896-901. doi:10.1111/jgs.12266
    • (2013) J Am Geriatr Soc. , vol.61 , pp. 896-901
    • McAdams-DeMarco, M.A.1    Law, A.2    Salter, M.L.3
  • 15
    • 70449730800 scopus 로고    scopus 로고
    • Frailty among HIV-infected persons in an urban outpatient care setting
    • Onen NF, Agbebi A, Shacham E, Stamm KE, Onen AR, Overton ET. Frailty among HIV-infected persons in an urban outpatient care setting. J Infect. 2009;59:346-352. doi:10.1016/j.jinf.2009.08.008
    • (2009) J Infect. , vol.59 , pp. 346-352
    • Onen, N.F.1    Agbebi, A.2    Shacham, E.3    Stamm, K.E.4    Onen, A.R.5    Overton, E.T.6
  • 16
    • 84872075650 scopus 로고    scopus 로고
    • Frailty in HIV-infected adults in South Africa
    • Pathai S, Gilbert C, Weiss HA, et al. Frailty in HIV-infected adults in South Africa. J Acquir Immune Defc Syndr. 2013;62:43-51. doi:10.1097/QAI.0b013e318273b631
    • (2013) J Acquir Immune Defc Syndr. , vol.62 , pp. 43-51
    • Pathai, S.1    Gilbert, C.2    Weiss, H.A.3
  • 17
    • 84873100763 scopus 로고    scopus 로고
    • Frailty HIV infection and mortality in an aging cohort of injection drug users
    • Piggott DA, Muzaale AD, Mehta SH, et al. Frailty, HIV infection, and mortality in an aging cohort of injection drug users. PLoS One. 2013;8:e54910. doi:10.1371/journal.pone.0054910
    • (2013) PLoS One. , vol.8 , pp. e54910
    • Piggott, D.A.1    Muzaale, A.D.2    Mehta, S.H.3
  • 18
    • 79955973916 scopus 로고    scopus 로고
    • Infammatory markers in population studies of aging
    • Singh T, Newman AB. Infammatory markers in population studies of aging. Ageing Res Rev. 2011;10:319-329. doi:10.1016/j.arr.2010.11.002
    • (2011) Ageing Res Rev. , vol.10 , pp. 319-329
    • Singh, T.1    Newman, A.B.2
  • 19
    • 84922470859 scopus 로고    scopus 로고
    • Aging and the burden of multimorbidity: Associations with infammatory and anabolic hormonal biomarkers
    • Fabbri E, An Y, Zoli M, et al. Aging and the burden of multimorbidity: associations with infammatory and anabolic hormonal biomarkers. J Gerontol A Biol Sci Med Sci. 2015;70:63-70. doi:10.1093/gerona/glu127
    • (2015) J Gerontol A Biol Sci Med Sci. , vol.70 , pp. 63-70
    • Fabbri, E.1    An, Y.2    Zoli, M.3
  • 20
    • 84900988267 scopus 로고    scopus 로고
    • Chronic infammation (infammaging) and its potential contribution to age-associated diseases
    • Franceschi C, Campisi J. Chronic infammation (infammaging) and its potential contribution to age-associated diseases. J Gerontol A Biol Sci Med Sci. 2014;69(suppl 1):S4-S9. doi:10.1093/gerona/glu057
    • (2014) J Gerontol A Biol Sci Med Sci. , vol.69 , pp. S4-S9
    • Franceschi, C.1    Campisi, J.2
  • 21
    • 75949090125 scopus 로고    scopus 로고
    • Total and cause-specifc mortality in the cardiovascular health study
    • Newman AB, Sachs MC, Arnold AM, et al. Total and cause-specifc mortality in the cardiovascular health study. J Gerontol A Biol Sci Med Sci. 2009;64:1251-1261. doi:10.1093/gerona/glp127
    • (2009) J Gerontol A Biol Sci Med Sci. , vol.64 , pp. 1251-1261
    • Newman, A.B.1    Sachs, M.C.2    Arnold, A.M.3
  • 22
    • 0141892842 scopus 로고    scopus 로고
    • Cytokines, insulin-like growth factor 1, sarcopenia, and mortality in very old community-dwelling men and women: The Framingham Heart Study
    • Roubenoff R, Parise H, Payette HA, et al. Cytokines, insulin-like growth factor 1, sarcopenia, and mortality in very old community-dwelling men and women: the Framingham Heart Study. Am J Med. 2003;115:429-435.
    • (2003) Am J Med. , vol.115 , pp. 429-435
    • Roubenoff, R.1    Parise, H.2    Payette, H.A.3
  • 23
    • 79551614790 scopus 로고    scopus 로고
    • HIV infection, infammation, immunosenescence, and aging
    • Deeks SG. HIV infection, infammation, immunosenescence, and aging. Annu Rev Med. 2011;62:141-155. doi:10.1146/annurev-med-042909-093756
    • (2011) Annu Rev Med. , vol.62 , pp. 141-155
    • Deeks, S.G.1
  • 24
    • 84879354628 scopus 로고    scopus 로고
    • Association of functional impairment with infammation and immune activation in HIV type 1-infected adults receiving effective antiretroviral therapy
    • Erlandson KM, Allshouse AA, Jankowski CM, et al. Association of functional impairment with infammation and immune activation in HIV type 1-infected adults receiving effective antiretroviral therapy. J Infect Dis. 2013;208:249-259. doi:10.1093/infdis/jit147
    • (2013) J Infect Dis. , vol.208 , pp. 249-259
    • Erlandson, K.M.1    Allshouse, A.A.2    Jankowski, C.M.3
  • 25
    • 84896740080 scopus 로고    scopus 로고
    • Infammatory co-morbidities in HIV+ individuals: Learning lessons from healthy ageing
    • Hearps AC, Martin GE, Rajasuriar R, Crowe SM. Infammatory co-morbidities in HIV+ individuals: learning lessons from healthy ageing. Curr HIV/AIDS Rep. 2014;11:20-34. doi:10.1007/s11904-013-0190-8
    • (2014) Curr HIV/AIDS Rep. , vol.11 , pp. 20-34
    • Hearps, A.C.1    Martin, G.E.2    Rajasuriar, R.3    Crowe, S.M.4
  • 26
    • 55949084601 scopus 로고    scopus 로고
    • Infammatory and coagulation biomarkers and mortality in patients with HIV infection
    • Kuller LH, Tracy R, Belloso W, et al. Infammatory and coagulation biomarkers and mortality in patients with HIV infection. PLoS Med. 2008;5:e203. doi:10.1371/journal.pmed.0050203
    • (2008) PLoS Med. , vol.5 , pp. e203
    • Kuller, L.H.1    Tracy, R.2    Belloso, W.3
  • 27
    • 84892372311 scopus 로고    scopus 로고
    • Can early therapy reduce infammation?
    • Sandler NG, Sereti I. Can early therapy reduce infammation? Curr Opin HIV AIDS. 2014;9:72-79. doi:10.1097/COH.0000000000000020
    • (2014) Curr Opin HIV AIDS. , vol.9 , pp. 72-79
    • Sandler, N.G.1    Sereti, I.2
  • 29
    • 84863092748 scopus 로고    scopus 로고
    • Frailty and the role of infam-mation, immunosenescence and cellular ageing in the very old: Cross-sectional fndings from the Newcastle 85+ Study
    • Collerton J, Martin-Ruiz C, Davies K, et al. Frailty and the role of infam-mation, immunosenescence and cellular ageing in the very old: cross-sectional fndings from the Newcastle 85+ Study. Mech Ageing Dev. 2012;133:456-466. doi:10.1016/j.mad.2012.05.005
    • (2012) Mech Ageing Dev. , vol.133 , pp. 456-466
    • Collerton, J.1    Martin-Ruiz, C.2    Davies, K.3
  • 32
    • 0037111615 scopus 로고    scopus 로고
    • Frailty and activation of the infammation and coagulation systems with and without clinical comorbidities: Results from the Cardiovascular Health Study
    • Walston J, McBurnie MA, Newman A, et al.; Cardiovascular Health Study. Frailty and activation of the infammation and coagulation systems with and without clinical comorbidities: results from the Cardiovascular Health Study. Arch Intern Med. 2002;162:2333-2341. doi:10.1001/archinte.162.20.2333
    • (2002) Arch Intern Med. , vol.162 , pp. 2333-2341
    • Walston, J.1    McBurnie, M.A.2    Newman, A.3
  • 33
    • 84896780657 scopus 로고    scopus 로고
    • Simple biologically informed infam-matory index of two serum cytokines predicts 10 year all-cause mortality in older adults
    • Varadhan R, Yao W, Matteini A, et al. Simple biologically informed infam-matory index of two serum cytokines predicts 10 year all-cause mortality in older adults. J Gerontol A Biol Sci Med Sci. 2014;69:165-173. doi:10.1093/gerona/glt023
    • (2014) J Gerontol A Biol Sci Med Sci. , vol.69 , pp. 165-173
    • Varadhan, R.1    Yao, W.2    Matteini, A.3
  • 34
    • 0026357723 scopus 로고
    • The ALIVE study, a longitudinal study of HIV-1 infection in intravenous drug users: Description of methods and characteristics of participants
    • Vlahov D, Anthony JC, Munoz A, et al. The ALIVE study, a longitudinal study of HIV-1 infection in intravenous drug users: description of methods and characteristics of participants. NIDA Res Monogr. 1991;109:75-100.
    • (1991) NIDA Res Monogr. , vol.109 , pp. 75-100
    • Vlahov, D.1    Anthony, J.C.2    Munoz, A.3
  • 35
    • 84891601622 scopus 로고    scopus 로고
    • Correlates of elevated interleukin-6 and C-reactive protein in persons with or at high risk for HCV and HIV infections
    • Salter ML, Lau B, Mehta SH, Go VF, Leng S, Kirk GD. Correlates of elevated interleukin-6 and C-reactive protein in persons with or at high risk for HCV and HIV infections. J Acquir Immune Defc Syndr. 2013;64:488-495. doi:10.1097/QAI.0b013e3182a7ee2e
    • (2013) J Acquir Immune Defc Syndr. , vol.64 , pp. 488-495
    • Salter, M.L.1    Lau, B.2    Mehta, S.H.3    Go, V.F.4    Leng, S.5    Kirk, G.D.6
  • 36
    • 78549273675 scopus 로고    scopus 로고
    • The biology of aging and frailty
    • Fedarko NS. The biology of aging and frailty. Clin Geriatr Med. 2011;27:27-37. doi:10.1016/j.cger.2010.08.006
    • (2011) Clin Geriatr Med. , vol.27 , pp. 27-37
    • Fedarko, N.S.1
  • 37
    • 84872436943 scopus 로고    scopus 로고
    • Enhanced CD4+ T-cell recovery with earlier HIV-1 antiretroviral therapy
    • Le T, Wright EJ, Smith DM, et al. Enhanced CD4+ T-cell recovery with earlier HIV-1 antiretroviral therapy. N Engl J Med. 2013;368:218-230. doi:10.1056/NEJMoa1110187
    • (2013) N Engl J Med. , vol.368 , pp. 218-230
    • Le Wright T, E.J.1    Smith, D.M.2
  • 38
    • 79953757456 scopus 로고    scopus 로고
    • The spectrum of engagement in HIV care and its relevance to test-and-treat strategies for prevention of HIV infection
    • Gardner EM, McLees MP, Steiner JF, Del Rio C, Burman WJ. The spectrum of engagement in HIV care and its relevance to test-and-treat strategies for prevention of HIV infection. Clin Infect Dis. 2011;52:793-800. doi:10.1093/cid/ciq243
    • (2011) Clin Infect Dis. , vol.52 , pp. 793-800
    • Gardner, E.M.1    McLees, M.P.2    Steiner, J.F.3    Del Rio, C.4    Burman, W.J.5
  • 39
    • 64249167491 scopus 로고    scopus 로고
    • Nonstructured treatment interruptions among injection drug users in Baltimore, MD
    • Kavasery R, Galai N, Astemborski J, et al. Nonstructured treatment interruptions among injection drug users in Baltimore, MD. J Acquir Immune Defc Syndr. 2009;50:360-366. doi:10.1097/QAI.0b013e318198a800
    • (2009) J Acquir Immune Defc Syndr. , vol.50 , pp. 360-366
    • Kavasery, R.1    Galai, N.2    Astemborski, J.3
  • 40
    • 84885425011 scopus 로고    scopus 로고
    • Longitudinal changes in engagement in care and viral suppression for HIV-infected injection drug users
    • Westergaard RP, Hess T, Astemborski J, Mehta SH, Kirk GD. Longitudinal changes in engagement in care and viral suppression for HIV-infected injection drug users. AIDS. 2013;27:2559-2566. doi:10.1097/QAD.0b013e328363bff2
    • (2013) AIDS. , vol.27 , pp. 2559-2566
    • Westergaard, R.P.1    Hess, T.2    Astemborski, J.3    Mehta, S.H.4    Kirk, G.D.5
  • 41
    • 80051744209 scopus 로고    scopus 로고
    • HIV infection in the etiology of lung cancer: Confounding, causality, and consequences
    • Kirk GD, Merlo CA; Lung HIV Study. HIV infection in the etiology of lung cancer: confounding, causality, and consequences. Proc Am Thorac Soc. 2011;8:326-332. doi:10.1513/pats.201009-061WR
    • (2011) Proc Am Thorac Soc. , vol.8 , pp. 326-332
    • Kirk, G.D.1    Merlo, C.A.2
  • 42
    • 33744913541 scopus 로고    scopus 로고
    • Research agenda for frailty in older adults: Toward a better understanding of physiology and etiology: Summary from the American Geriatrics Society/National Institute on Aging Research Conference on Frailty in Older Adults
    • Walston J, Hadley EC, Ferrucci L, et al. Research agenda for frailty in older adults: toward a better understanding of physiology and etiology: summary from the American Geriatrics Society/National Institute on Aging Research Conference on Frailty in Older Adults. J Am Geriatr Soc. 2006;54:991-1001. doi:10.1111/j.1532-5415.2006.00745.x
    • (2006) J Am Geriatr Soc. , vol.54 , pp. 991-1001
    • Walston, J.1    Hadley, E.C.2    Ferrucci, L.3
  • 43
    • 84896756831 scopus 로고    scopus 로고
    • The "cytokine for gerontologists" has some company
    • Roubenoff R. The "cytokine for gerontologists" has some company. J Ger-ontol A Biol Sci Med Sci. 2014;69:163-164. doi:10.1093/gerona/glt184
    • (2014) J Ger-ontol A Biol Sci Med Sci. , vol.69 , pp. 163-164
    • Roubenoff, R.1
  • 44
    • 84896795024 scopus 로고    scopus 로고
    • Do changes in circulating biomark-ers track with each other and with functional changes in older adults?
    • Sanders JL, Ding V, Arnold AM, et al. Do changes in circulating biomark-ers track with each other and with functional changes in older adults? J Gerontol A Biol Sci Med Sci. 2014;69:174-181. doi:10.1093/gerona/glt088
    • (2014) J Gerontol A Biol Sci Med Sci. , vol.69 , pp. 174-181
    • Sanders, J.L.1    Ding, V.2    Arnold, A.M.3
  • 45
    • 84926674717 scopus 로고    scopus 로고
    • Oxidative stress markers and all-cause mortality at older age: A population-based cohort study
    • Schöttker B, Saum KU, Jansen EH, et al. Oxidative stress markers and all-cause mortality at older age: a population-based cohort study. J Gerontol A Biol Sci Med Sci. 2015;70:518-524. doi:10.1093/gerona/glu111
    • (2015) J Gerontol A Biol Sci Med Sci. , vol.70 , pp. 518-524
    • Schöttker, B.1    Saum, K.U.2    Jansen, E.H.3
  • 46
    • 84869116281 scopus 로고    scopus 로고
    • The infuence of sex race/ethnicity and educational attainment on human immunodefciency virus death rates among adults 1993-2007
    • Simard EP, Fransua M, Naishadham D, Jemal A. The infuence of sex, race/ethnicity, and educational attainment on human immunodefciency virus death rates among adults, 1993-2007. Arch Intern Med. 2012;172:1591-1598. doi:10.1001/archinternmed.2012.4508
    • (2012) Arch Intern Med. , vol.172 , pp. 1591-1598
    • Simard, E.P.1    Fransua, M.2    Naishadham, D.3    Jemal, A.4


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