메뉴 건너뛰기




Volumn 98, Issue 4, 2005, Pages 1154-1162

The anti-inflammatory effect of exercise

Author keywords

Aging; Atherosclerosis; Cytokines; Diabetes; Physical activity

Indexed keywords

C REACTIVE PROTEIN; CYTOKINE; INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; INTERLEUKIN 10; INTERLEUKIN 1BETA; INTERLEUKIN 6; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR ALPHA RECEPTOR;

EID: 15444374348     PISSN: 87507587     EISSN: None     Source Type: Journal    
DOI: 10.1152/japplphysiol.00164.2004     Document Type: Review
Times cited : (2303)

References (162)
  • 1
    • 0037054033 scopus 로고    scopus 로고
    • Relationship between physical activity and inflammation among apparently healthy middle-aged and older US adults
    • Abramson JL and Vaccarino V. Relationship between physical activity and inflammation among apparently healthy middle-aged and older US adults. Arch Intern Med 162: 1286-1292, 2002.
    • (2002) Arch Intern Med , vol.162 , pp. 1286-1292
    • Abramson, J.L.1    Vaccarino, V.2
  • 2
    • 0026611673 scopus 로고
    • IL-6 and NF-IL6 in acute-phase response and viral infection
    • Akira S and Kishimoto T. IL-6 and NF-IL6 in acute-phase response and viral infection. Immunol Rev 127: 25-50, 1992.
    • (1992) Immunol Rev , vol.127 , pp. 25-50
    • Akira, S.1    Kishimoto, T.2
  • 3
    • 0027421831 scopus 로고
    • Interleukin-6 in biology and medicine
    • Akira S, Taga T, and Kishimoto T. Interleukin-6 in biology and medicine. Adv Immunol 54: 1-78, 1993.
    • (1993) Adv Immunol , vol.54 , pp. 1-78
    • Akira, S.1    Taga, T.2    Kishimoto, T.3
  • 5
    • 0035488931 scopus 로고    scopus 로고
    • The relation of markers of inflammation to the development of glucose disorders in the elderly: The Cardiovascular Health Study
    • Barzilay JI, Abraham L, Heckbert SR, Cushman M, Kuller LH, Resnick HE, and Tracy RP. The relation of markers of inflammation to the development of glucose disorders in the elderly: the Cardiovascular Health Study. Diabetes 50: 2384-2389, 2001.
    • (2001) Diabetes , vol.50 , pp. 2384-2389
    • Barzilay, J.I.1    Abraham, L.2    Heckbert, S.R.3    Cushman, M.4    Kuller, L.H.5    Resnick, H.E.6    Tracy, R.P.7
  • 7
    • 0035012889 scopus 로고    scopus 로고
    • Is physical activity or physical fitness more important in defining health benefits?
    • Blair SN, Cheng Y, and Holder JS. Is physical activity or physical fitness more important in defining health benefits? Med Sci Sports Exerc 33: S379-S399, 2001.
    • (2001) Med Sci Sports Exerc , vol.33
    • Blair, S.N.1    Cheng, Y.2    Holder, J.S.3
  • 8
    • 0026457998 scopus 로고
    • Contrasting mechanisms for suppression of macrophage cytokine release by transforming growth factor-beta and interleukin-10
    • Bogdan C, Paik J, Vodovotz Y, and Nathan C. Contrasting mechanisms for suppression of macrophage cytokine release by transforming growth factor-beta and interleukin-10. J Biol Chem 267: 23301-23308, 1992.
    • (1992) J Biol Chem , vol.267 , pp. 23301-23308
    • Bogdan, C.1    Paik, J.2    Vodovotz, Y.3    Nathan, C.4
  • 9
    • 0036345297 scopus 로고    scopus 로고
    • Neutralization of tumor necrosis factor reverses age-induced impairment of insulin responsiveness in skeletal muscle of Sprague-Dawley rats
    • Borst SE and Bagby GJ. Neutralization of tumor necrosis factor reverses age-induced impairment of insulin responsiveness in skeletal muscle of Sprague-Dawley rats. Metabolism 51: 1061-1064, 2002.
    • (2002) Metabolism , vol.51 , pp. 1061-1064
    • Borst, S.E.1    Bagby, G.J.2
  • 11
    • 0035850403 scopus 로고    scopus 로고
    • Effects of exercise on glycemic control and body mass in type 2 diabetes mellitus: A meta-analysis of controlled clinical trials
    • Boule NG, Haddad E, Kenny GP, Wells GA, and Sigal RJ. Effects of exercise on glycemic control and body mass in type 2 diabetes mellitus: a meta-analysis of controlled clinical trials. JAMA 286: 1218-1227, 2001.
    • (2001) JAMA , vol.286 , pp. 1218-1227
    • Boule, N.G.1    Haddad, E.2    Kenny, G.P.3    Wells, G.A.4    Sigal, R.J.5
  • 12
    • 4544259980 scopus 로고    scopus 로고
    • Cytokine regulation of skeletal muscle fatty acid metabolism: Effect of interleukin-6 and tumor necrosis factor-α
    • Bruce CR and Dyck DJ. Cytokine regulation of skeletal muscle fatty acid metabolism: effect of interleukin-6 and tumor necrosis factor-α. Am J Physiol Endocrinol Metab 287: E616-E621, 2004.
    • (2004) Am J Physiol Endocrinol Metab , vol.287
    • Bruce, C.R.1    Dyck, D.J.2
  • 14
    • 0842326601 scopus 로고    scopus 로고
    • The IL-6 -174>C polymorphism is associated with cardiovascular diseases and mortality in 80-year-old humans
    • Bruunsgaard H, Christiansen L, Pedersen AN, Schroll M, Jorgensen T, and Pedersen BK. The IL-6 -174>C polymorphism is associated with cardiovascular diseases and mortality in 80-year-old humans. Exp Gerontol 39: 255-261, 2004.
    • (2004) Exp Gerontol , vol.39 , pp. 255-261
    • Bruunsgaard, H.1    Christiansen, L.2    Pedersen, A.N.3    Schroll, M.4    Jorgensen, T.5    Pedersen, B.K.6
  • 15
    • 0033527714 scopus 로고    scopus 로고
    • Exercise induces recruitment of lymphocytes with an activated phenotype and short telomere lengths in young and elderly humans
    • Bruunsgaard H, Jensen MS, Schjerling P, Halkjaer-Kristensen J, Ogawa K, Skinhoj P, and Pedersen BK. Exercise induces recruitment of lymphocytes with an activated phenotype and short telomere lengths in young and elderly humans. Life Sci 65: 2623-2633, 1999.
    • (1999) Life Sci , vol.65 , pp. 2623-2633
    • Bruunsgaard, H.1    Jensen, M.S.2    Schjerling, P.3    Halkjaer-Kristensen, J.4    Ogawa, K.5    Skinhoj, P.6    Pedersen, B.K.7
  • 18
    • 3142710172 scopus 로고    scopus 로고
    • Interleukin-6 and tumor necrosis factor-alpha are not increased in patients with type 2 diabetes: Evidence that plasma IL-6 is related to fat mass and not insulin responsiveness
    • Carey AL, Bruce CR, Sacchetti M, Anderson MJ, Olson D, Saltin B, Hawley JA, and Febbraio MA. Interleukin-6 and tumor necrosis factor-alpha are not increased in patients with type 2 diabetes: evidence that plasma IL-6 is related to fat mass and not insulin responsiveness. Diabetologia 47: 1029-1037, 2004.
    • (2004) Diabetologia , vol.47 , pp. 1029-1037
    • Carey, A.L.1    Bruce, C.R.2    Sacchetti, M.3    Anderson, M.J.4    Olson, D.5    Saltin, B.6    Hawley, J.A.7    Febbraio, M.A.8
  • 19
    • 0347318052 scopus 로고    scopus 로고
    • The AMP-activated protein kinase cascade - A unifying system for energy control
    • Carling D. The AMP-activated protein kinase cascade - a unifying system for energy control. Trends Biochem Sci 29: 18-24, 2004.
    • (2004) Trends Biochem Sci , vol.29 , pp. 18-24
    • Carling, D.1
  • 23
    • 0034880752 scopus 로고    scopus 로고
    • Pro-inflammatory cytokines and adipose tissue
    • Coppack SW. Pro-inflammatory cytokines and adipose tissue. Proc Nutr Soc 60: 349-356, 2001.
    • (2001) Proc Nutr Soc , vol.60 , pp. 349-356
    • Coppack, S.W.1
  • 24
    • 0348222671 scopus 로고    scopus 로고
    • Inflammation: The link between insulin resistance, obesity and diabetes
    • Dandona P, Aljada A, and Bandyopadhyay A. Inflammation: the link between insulin resistance, obesity and diabetes. Trends Immunol 25: 4-7, 2004.
    • (2004) Trends Immunol , vol.25 , pp. 4-7
    • Dandona, P.1    Aljada, A.2    Bandyopadhyay, A.3
  • 25
    • 0025777448 scopus 로고
    • Interleukin-1 and interleukin-1 antagonism
    • Dinarello CA. Interleukin-1 and interleukin-1 antagonism. Blood 77: 1627-1652, 1991.
    • (1991) Blood , vol.77 , pp. 1627-1652
    • Dinarello, C.A.1
  • 26
    • 0026873276 scopus 로고
    • Interleukin-1 and tumor necrosis factor: Effector cytokines in autoimmune diseases
    • Dinarello CA. Interleukin-1 and tumor necrosis factor: effector cytokines in autoimmune diseases. Semin Immunol 4: 133-145, 1992.
    • (1992) Semin Immunol , vol.4 , pp. 133-145
    • Dinarello, C.A.1
  • 27
    • 0034618862 scopus 로고    scopus 로고
    • The role of the interleukin-1-receptor antagonist in blocking inflammation mediated by interleukin-1
    • Dinarello CA. The role of the interleukin-1-receptor antagonist in blocking inflammation mediated by interleukin-1. N Engl J Med 343: 732-734, 2000.
    • (2000) N Engl J Med , vol.343 , pp. 732-734
    • Dinarello, C.A.1
  • 31
    • 0034763480 scopus 로고    scopus 로고
    • The acute phase response and exercise: Court and field sports
    • Fallon KE, Fallon SK, and Boston T. The acute phase response and exercise: court and field sports. Br J Sports Med 35: 170-173, 2001.
    • (2001) Br J Sports Med , vol.35 , pp. 170-173
    • Fallon, K.E.1    Fallon, S.K.2    Boston, T.3
  • 32
    • 3042721664 scopus 로고    scopus 로고
    • Interleukin-6 is a novel factor mediating glucose homeostasis during skeletal muscle contraction
    • Febbraio MA, Hiscock N, Sacchetti M, Fischer CP, and Pedersen BK. Interleukin-6 is a novel factor mediating glucose homeostasis during skeletal muscle contraction. Diabetes 53: 1643-1648, 2004.
    • (2004) Diabetes , vol.53 , pp. 1643-1648
    • Ma, F.1    Hiscock, N.2    Sacchetti, M.3    Fischer, C.P.4    Pedersen, B.K.5
  • 33
    • 0036720342 scopus 로고    scopus 로고
    • Muscle-derived interleukin-6: Mechanisms for activation and possible biological roles
    • Febbraio MA and Pedersen BK. Muscle-derived interleukin-6: mechanisms for activation and possible biological roles. FASEB J 16: 1335-1347, 2002.
    • (2002) FASEB J , vol.16 , pp. 1335-1347
    • Febbraio, M.A.1    Pedersen, B.K.2
  • 35
    • 0026660277 scopus 로고
    • Role of cytokines in inducing hyperlipidemia
    • Feingold KR and Grunfeld C. Role of cytokines in inducing hyperlipidemia. Diabetes 41, Suppl 2: 97-101, 1992.
    • (1992) Diabetes , vol.41 , Issue.SUPPL. 2 , pp. 97-101
    • Feingold, K.R.1    Grunfeld, C.2
  • 36
    • 0036230414 scopus 로고    scopus 로고
    • Elevated levels of acute-phase proteins and plasminogen activator inhibitor-1 predict the development of type 2 diabetes: The insulin resistance atherosclerosis study
    • Festa A, D'Agostino R Jr, Tracy RP, and Haffner SM. Elevated levels of acute-phase proteins and plasminogen activator inhibitor-1 predict the development of type 2 diabetes: the insulin resistance atherosclerosis study. Diabetes 51: 1131-1137, 2002.
    • (2002) Diabetes , vol.51 , pp. 1131-1137
    • Festa, A.1    D'Agostino Jr., R.2    Tracy, R.P.3    Haffner, S.M.4
  • 37
    • 0025884625 scopus 로고
    • Tumor necrosis factor. Characterization at the molecular, cellular and in vivo level
    • Fiers W. Tumor necrosis factor. Characterization at the molecular, cellular and in vivo level. FEBS Lett 285: 199-212, 1991.
    • (1991) FEBS Lett , vol.285 , pp. 199-212
    • Fiers, W.1
  • 38
  • 39
    • 0036140124 scopus 로고    scopus 로고
    • Leukocyte count, erythrocyte sedimentation rate, and diabetes incidence in a national sample of US adults
    • Ford ES. Leukocyte count, erythrocyte sedimentation rate, and diabetes incidence in a national sample of US adults. Am J Epidemiol 155: 57-64, 2002.
    • (2002) Am J Epidemiol , vol.155 , pp. 57-64
    • Ford, E.S.1
  • 40
    • 0036312978 scopus 로고    scopus 로고
    • C-reactive protein is an independent predictor of risk for the development of diabetes in the West of Scotland Coronary Prevention Study
    • Freeman DJ, Norrie J, Caslake MJ, Gaw A, Ford I, Lowe GD, O'Reilly DS, Packard CJ, and Sattar N. C-reactive protein is an independent predictor of risk for the development of diabetes in the West of Scotland Coronary Prevention Study. Diabetes 51: 1596-1600, 2002.
    • (2002) Diabetes , vol.51 , pp. 1596-1600
    • Freeman, D.J.1    Norrie, J.2    Caslake, M.J.3    Gaw, A.4    Ford, I.5    Lowe, G.D.6    O'Reilly, D.S.7    Packard, C.J.8    Sattar, N.9
  • 41
    • 0031762908 scopus 로고    scopus 로고
    • Omental and subcutaneous adipose tissues of obese subjects release interleukin-6: Depot difference and regulation by glucocorticoid
    • Fried SK, Bunkin DA, and Greenberg AS. Omental and subcutaneous adipose tissues of obese subjects release interleukin-6: depot difference and regulation by glucocorticoid. J Clin Endocrinol Metab 83: 847-850, 1998.
    • (1998) J Clin Endocrinol Metab , vol.83 , pp. 847-850
    • Fried, S.K.1    Bunkin, D.A.2    Greenberg, A.S.3
  • 42
    • 0030961241 scopus 로고    scopus 로고
    • Interleukin 1 receptor antagonist (IL-1Ra) is an acute-phase protein
    • Gabay C, Smith MF, Eidlen D, and Arend WP. Interleukin 1 receptor antagonist (IL-1Ra) is an acute-phase protein. J Clin Invest 99: 2930-2940, 1997.
    • (1997) J Clin Invest , vol.99 , pp. 2930-2940
    • Gabay, C.1    Smith, M.F.2    Eidlen, D.3    Arend, W.P.4
  • 43
    • 0032960948 scopus 로고    scopus 로고
    • Leukemia inhibitory factor, Interleukin 6, and other cytokines using the GP130 transducing receptor: Roles in inflammation and injury
    • Gadient RA and Patterson PH. Leukemia inhibitory factor, Interleukin 6, and other cytokines using the GP130 transducing receptor: roles in inflammation and injury. Stem Cells 17: 127-137, 1999.
    • (1999) Stem Cells , vol.17 , pp. 127-137
    • Gadient, R.A.1    Patterson, P.H.2
  • 44
    • 0033525876 scopus 로고    scopus 로고
    • Tumor necrosis factor alpha stimulates lipolysis in adipocytes by decreasing Gi protein concentrations
    • Gasic S, Tian B, and Green A. Tumor necrosis factor alpha stimulates lipolysis in adipocytes by decreasing Gi protein concentrations. J Biol Chem 274: 6770-6775, 1999.
    • (1999) J Biol Chem , vol.274 , pp. 6770-6775
    • Gasic, S.1    Tian, B.2    Green, A.3
  • 45
    • 0035242622 scopus 로고    scopus 로고
    • Association between physical activity and markers of inflammation in a healthy elderly population
    • Geffken DF, Cushman M, Burke GL, Polak JF, Sakkinen PA, and Tracy RP. Association between physical activity and markers of inflammation in a healthy elderly population. Am J Epidemiol 153: 242-250, 2001.
    • (2001) Am J Epidemiol , vol.153 , pp. 242-250
    • Geffken, D.F.1    Cushman, M.2    Burke, G.L.3    Polak, J.F.4    Sakkinen, P.A.5    Tracy, R.P.6
  • 46
    • 0028302002 scopus 로고
    • Tumor necrosis factor increases the rate of lipolysis in primary cultures of adipocytes without altering levels of hormone-sensitive lipase
    • Green A, Dobias SB, Walters DJ, and Brasier AR. Tumor necrosis factor increases the rate of lipolysis in primary cultures of adipocytes without altering levels of hormone-sensitive lipase. Endocrinology 134: 2581-2588, 1994.
    • (1994) Endocrinology , vol.134 , pp. 2581-2588
    • Green, A.1    Dobias, S.B.2    Walters, D.J.3    Brasier, A.R.4
  • 47
    • 0035034309 scopus 로고    scopus 로고
    • Effects of tumor necrosis factor-alpha on insulin action in cultured human muscle cells
    • Halse R, Pearson SL, McCormack JG, Yeaman SJ, and Taylor R. Effects of tumor necrosis factor-alpha on insulin action in cultured human muscle cells. Diabetes 50: 1102-1109, 2001.
    • (2001) Diabetes , vol.50 , pp. 1102-1109
    • Halse, R.1    Pearson, S.L.2    McCormack, J.G.3    Yeaman, S.J.4    Taylor, R.5
  • 48
    • 0036833814 scopus 로고    scopus 로고
    • Prospective study of C-reactive protein in relation to the development of diabetes and metabolic syndrome in the Mexico City Diabetes Study
    • Han TS, Sattar N, Williams K, Gonzalez-Villalpando C, Lean ME, and Haffner SM. Prospective study of C-reactive protein in relation to the development of diabetes and metabolic syndrome in the Mexico City Diabetes Study. Diabetes Care 25: 2016-2021, 2002.
    • (2002) Diabetes Care , vol.25 , pp. 2016-2021
    • Han, T.S.1    Sattar, N.2    Williams, K.3    Gonzalez-Villalpando, C.4    Lean, M.E.5    Haffner, S.M.6
  • 49
    • 0030819159 scopus 로고    scopus 로고
    • Carrying the burden of cardiovascular risk in old age: Associations of weight and weight change with prevalent cardiovascular disease, risk factors, and health status in the Cardiovascular Health Study
    • Harris TB, Savage PJ, Tell GS, Haan M, Kumanyika S, and Lynch JC. Carrying the burden of cardiovascular risk in old age: associations of weight and weight change with prevalent cardiovascular disease, risk factors, and health status in the Cardiovascular Health Study. Am J Clin Nutr 66: 837-844, 1997.
    • (1997) Am J Clin Nutr , vol.66 , pp. 837-844
    • Harris, T.B.1    Savage, P.J.2    Tell, G.S.3    Haan, M.4    Kumanyika, S.5    Lynch, J.C.6
  • 50
    • 0031033822 scopus 로고    scopus 로고
    • Xanthine oxidase in human skeletal muscle following eccentric exercise: A role of inflammation
    • Hellsten Y, Frandsen U, Orthenblad N, Sjodin N, and Richter EA. Xanthine oxidase in human skeletal muscle following eccentric exercise: a role of inflammation. J Physiol 498: 239-248, 1997.
    • (1997) J Physiol , vol.498 , pp. 239-248
    • Hellsten, Y.1    Frandsen, U.2    Orthenblad, N.3    Sjodin, N.4    Richter, E.A.5
  • 51
    • 4143052910 scopus 로고    scopus 로고
    • Skeletal myocytes are a source of interleukin-6 mRNA expression and protein release during contraction: Evidence of fiber type specificity
    • Hiscock N, Chan MH, Bisucci T, Darby IA, and Febbraio MA. Skeletal myocytes are a source of interleukin-6 mRNA expression and protein release during contraction: evidence of fiber type specificity. FASEB J 18: 992-994, 2004.
    • (2004) FASEB J , vol.18 , pp. 992-994
    • Hiscock, N.1    Chan, M.H.2    Bisucci, T.3    Darby, I.A.4    Febbraio, M.A.5
  • 52
    • 0032925340 scopus 로고    scopus 로고
    • Mechanisms of TNF-alpha-induced insulin resistance
    • Hotamisligil GS. Mechanisms of TNF-alpha-induced insulin resistance. Exp Clin Endocrinol Diabetes 107: 119-125, 1999.
    • (1999) Exp Clin Endocrinol Diabetes , vol.107 , pp. 119-125
    • Hotamisligil, G.S.1
  • 53
    • 0030061922 scopus 로고    scopus 로고
    • IRS-1-mediated inhibition of insulin receptor tyrosine kinase activity in TNF-alpha- and obesity-induced insulin resistance
    • Hotamisligil GS, Peraldi P, Budavari A, Ellis R, White MF, and Spiegelman BM. IRS-1-mediated inhibition of insulin receptor tyrosine kinase activity in TNF-alpha- and obesity-induced insulin resistance. Science 271: 665-668, 1996.
    • (1996) Science , vol.271 , pp. 665-668
    • Hotamisligil, G.S.1    Peraldi, P.2    Budavari, A.3    Ellis, R.4    White, M.F.5    Spiegelman, B.M.6
  • 54
    • 0027459878 scopus 로고
    • Adipose expression of tumor necrosis factor-alpha: Direct role in obesity-linked insulin resistance
    • Hotamisligil GS, Shargill NS, and Spiegelman BM. Adipose expression of tumor necrosis factor-alpha: direct role in obesity-linked insulin resistance. Science 259: 87-91, 1993.
    • (1993) Science , vol.259 , pp. 87-91
    • Hotamisligil, G.S.1    Shargill, N.S.2    Spiegelman, B.M.3
  • 58
    • 0035651023 scopus 로고    scopus 로고
    • Transcriptional activation of the IL-6 gene in human contracting skeletal muscle: Influence of muscle glycogen content
    • Keller C, Steensberg A, Pilegaard H, Osada T, Saltin B, Pedersen BK, and Neufer PD. Transcriptional activation of the IL-6 gene in human contracting skeletal muscle: influence of muscle glycogen content. FASEB J 15: 2748-2750, 2001.
    • (2001) FASEB J , vol.15 , pp. 2748-2750
    • Keller, C.1    Steensberg, A.2    Pilegaard, H.3    Osada, T.4    Saltin, B.5    Pedersen, B.K.6    Neufer, P.D.7
  • 62
    • 0037387196 scopus 로고    scopus 로고
    • Inflammatory markers and exercise: Differences related to exercise type
    • King DE, Carek P, Mainous AG III, and Pearson WS. Inflammatory markers and exercise: differences related to exercise type. Med Sci Sports Exerc 35: 575-581, 2003.
    • (2003) Med Sci Sports Exerc , vol.35 , pp. 575-581
    • King, D.E.1    Carek, P.2    Mainous III, A.G.3    Pearson, W.S.4
  • 63
    • 0030862033 scopus 로고    scopus 로고
    • The -308 tumor necrosis factor-alpha promoter polymorphism effects transcription
    • Kroeger KM, Carville KS, and Abraham LJ. The -308 tumor necrosis factor-alpha promoter polymorphism effects transcription. Mol Immunol 34: 391-399, 1997.
    • (1997) Mol Immunol , vol.34 , pp. 391-399
    • Kroeger, K.M.1    Carville, K.S.2    Abraham, L.J.3
  • 65
    • 0037312898 scopus 로고    scopus 로고
    • The C-174G promoter polymorphism of the IL-6 gene affects energy expenditure and insulin sensitivity
    • Kubaszek A, Pihlajamaki J, Punnonen K, Karhapaa P, Vauhkonen I, and Laakso M. The C-174G promoter polymorphism of the IL-6 gene affects energy expenditure and insulin sensitivity. Diabetes 52: 558-561, 2003.
    • (2003) Diabetes , vol.52 , pp. 558-561
    • Kubaszek, A.1    Pihlajamaki, J.2    Punnonen, K.3    Karhapaa, P.4    Vauhkonen, I.5    Laakso, M.6
  • 67
    • 0036687485 scopus 로고    scopus 로고
    • Substantial elevation of interleukin-6 concentration in peritendinous tissue, in contrast to muscle, following prolonged exercise in humans
    • Langberg H, Olesen JL, Gemmer C, and Kjaer M. Substantial elevation of interleukin-6 concentration in peritendinous tissue, in contrast to muscle, following prolonged exercise in humans. J Physiol 542: 985-990, 2002.
    • (2002) J Physiol , vol.542 , pp. 985-990
    • Langberg, H.1    Olesen, J.L.2    Gemmer, C.3    Kjaer, M.4
  • 68
    • 0037180771 scopus 로고    scopus 로고
    • Inflammation in atherosclerosis
    • Libby P. Inflammation in atherosclerosis. Nature 420: 868-874, 2002.
    • (2002) Nature , vol.420 , pp. 868-874
    • Libby, P.1
  • 69
    • 0037022910 scopus 로고    scopus 로고
    • Inflammation and atherosclerosis
    • Libby P, Ridker PM, and Maseri A. Inflammation and atherosclerosis. Circulation 105: 1135-1143, 2002.
    • (2002) Circulation , vol.105 , pp. 1135-1143
    • Libby, P.1    Ridker, P.M.2    Maseri, A.3
  • 71
    • 0037101936 scopus 로고    scopus 로고
    • Interleukin-6 production in human subcutaneous abdominal adipose tissue: The effect of exercise
    • Lyngso D, Simonsen L, and Bulow J. Interleukin-6 production in human subcutaneous abdominal adipose tissue: the effect of exercise. J Physiol 543: 373-378, 2002.
    • (2002) J Physiol , vol.543 , pp. 373-378
    • Lyngso, D.1    Simonsen, L.2    Bulow, J.3
  • 72
    • 0028937828 scopus 로고
    • Anti-gamma interferon and anti-interleukin-6 antibodies affect staphylococcal enterotoxin B-induced weight loss, hypoglycemia, and cytokine release in D-galactosamine-sensitized and unsensitized mice
    • Matthys P, Mitera T, Heremans H, Van Damme J, and Billiau A. Anti-gamma interferon and anti-interleukin-6 antibodies affect staphylococcal enterotoxin B-induced weight loss, hypoglycemia, and cytokine release in D-galactosamine-sensitized and unsensitized mice. Infect Immun 63: 1158-1164, 1995.
    • (1995) Infect Immun , vol.63 , pp. 1158-1164
    • Matthys, P.1    Mitera, T.2    Heremans, H.3    Van Damme, J.4    Billiau, A.5
  • 73
    • 0033955506 scopus 로고    scopus 로고
    • Reduction of the plasma concentration of C-reactive protein following nine months of endurance training
    • Mattusch F, Dufaux B, Heine O, Mertens I, and Rost R. Reduction of the plasma concentration of C-reactive protein following nine months of endurance training. Int J Sports Med 21: 21-24, 2000.
    • (2000) Int J Sports Med , vol.21 , pp. 21-24
    • Mattusch, F.1    Dufaux, B.2    Heine, O.3    Mertens, I.4    Rost, R.5
  • 74
    • 0035055823 scopus 로고    scopus 로고
    • Relationship between serum tumor necrosis factor-alpha and insulin resistance in obese men with Type 2 diabetes mellitus
    • Mishima Y, Kuyama A, Tada A, Takahashi K, Ishioka T, and Kibata M. Relationship between serum tumor necrosis factor-alpha and insulin resistance in obese men with Type 2 diabetes mellitus. Diabetes Res Clin Pract 52: 119-123, 2001.
    • (2001) Diabetes Res Clin Pract , vol.52 , pp. 119-123
    • Mishima, Y.1    Kuyama, A.2    Tada, A.3    Takahashi, K.4    Ishioka, T.5    Kibata, M.6
  • 77
    • 0033771019 scopus 로고    scopus 로고
    • Exercise elevates plasma levels but not gene expression of IL-1β, IL-6, and TNF-α in blood mononuclear cells
    • Moldoveanu AI, Shephard RJ, and Shek PN. Exercise elevates plasma levels but not gene expression of IL-1β, IL-6, and TNF-α in blood mononuclear cells. J Appl Physiol 89: 1499-1504, 2000.
    • (2000) J Appl Physiol , vol.89 , pp. 1499-1504
    • Moldoveanu, A.I.1    Shephard, R.J.2    Shek, P.N.3
  • 79
    • 0030996001 scopus 로고    scopus 로고
    • Global mortality, disability, and the contribution of risk factors: Global Burden of Disease Study
    • Murray CJ and Lopez AD. Global mortality, disability, and the contribution of risk factors: Global Burden of Disease Study. Lancet 349: 1436-1442, 1997.
    • (1997) Lancet , vol.349 , pp. 1436-1442
    • Murray, C.J.1    Lopez, A.D.2
  • 80
    • 0036164733 scopus 로고    scopus 로고
    • White blood-cell count and the risk of impaired fasting glucose or Type II diabetes in middle-aged Japanese men
    • Nakanishi N, Yoshida H, Matsuo Y, Suzuki K, and Tatara K. White blood-cell count and the risk of impaired fasting glucose or Type II diabetes in middle-aged Japanese men. Diabetologia 45: 42-48, 2002.
    • (2002) Diabetologia , vol.45 , pp. 42-48
    • Nakanishi, N.1    Yoshida, H.2    Matsuo, Y.3    Suzuki, K.4    Tatara, K.5
  • 81
    • 15644366033 scopus 로고    scopus 로고
    • Carbohydrate and the cytokine response to 2.5 hours of running
    • Nehlsen-Canarella SL, Fagoaga OR, and Nieman DC. Carbohydrate and the cytokine response to 2.5 hours of running. J Appl Physiol 82: 1662-1667, 1997.
    • (1997) J Appl Physiol , vol.82 , pp. 1662-1667
    • Nehlsen-Canarella, S.L.1    Fagoaga, O.R.2    Nieman, D.C.3
  • 86
    • 2642558925 scopus 로고    scopus 로고
    • Treatment of rheumatoid arthritis with humanized anti-interleukin-6 receptor antibody: A multicenter, double-blind, placebo-controlled trial
    • Nishimoto N, Yoshizaki K, Miyasaka N, Yamamoto K, Kawai S, Takeuchi T, Hashimoto J, Azuma J, and Kishimoto T. Treatment of rheumatoid arthritis with humanized anti-interleukin-6 receptor antibody: a multicenter, double-blind, placebo-controlled trial. Arthritis Rheum 50: 1761-1769, 2004.
    • (2004) Arthritis Rheum , vol.50 , pp. 1761-1769
    • Nishimoto, N.1    Yoshizaki, K.2    Miyasaka, N.3    Yamamoto, K.4    Kawai, S.5    Takeuchi, T.6    Hashimoto, J.7    Azuma, J.8    Kishimoto, T.9
  • 88
    • 0028073768 scopus 로고
    • The cytokine response to strenuous exercise
    • Northoff H, Weinstock C, and Berg A. The cytokine response to strenuous exercise. Int J Sports Med 15: 167-171, 1994.
    • (1994) Int J Sports Med , vol.15 , pp. 167-171
    • Northoff, H.1    Weinstock, C.2    Berg, A.3
  • 89
    • 0036686906 scopus 로고    scopus 로고
    • Interleukin-6 release from the human brain during prolonged exercise
    • Nybo L, Nielsen B, Pedersen BK, Moller K, and Secher NH. Interleukin-6 release from the human brain during prolonged exercise. J Physiol 542: 991-995, 2002.
    • (2002) J Physiol , vol.542 , pp. 991-995
    • Nybo, L.1    Nielsen, B.2    Pedersen, B.K.3    Moller, K.4    Secher, N.H.5
  • 90
    • 0024405231 scopus 로고
    • Cachectin/tumor necrosis factor and interleukin-1 show different modes of combined effect on lipoprotein lipase activity and intracellular lipolysis in 3T3-L1 cells
    • Ogawa H, Nielsen S, and Kawakami M. Cachectin/tumor necrosis factor and interleukin-1 show different modes of combined effect on lipoprotein lipase activity and intracellular lipolysis in 3T3-L1 cells. Biochim Biophys Acta 1003: 131-135, 1989.
    • (1989) Biochim Biophys Acta , vol.1003 , pp. 131-135
    • Ogawa, H.1    Nielsen, S.2    Kawakami, M.3
  • 93
    • 0033557703 scopus 로고    scopus 로고
    • Pro- and anti-inflammatory cytokine balance in strenuous exercise in humans
    • Ostrowski K, Rohde T, Asp S, Schjerling P, and Pedersen BK. Pro- and anti-inflammatory cytokine balance in strenuous exercise in humans. J Physiol 515: 287-291, 1999.
    • (1999) J Physiol , vol.515 , pp. 287-291
    • Ostrowski, K.1    Rohde, T.2    Asp, S.3    Schjerling, P.4    Pedersen, B.K.5
  • 94
    • 0031895668 scopus 로고    scopus 로고
    • Evidence that IL-6 is produced in skeletal muscle during prolonged running
    • Ostrowski K, Rohde T, Zacho M, Asp S, and Pedersen BK. Evidence that IL-6 is produced in skeletal muscle during prolonged running. J Physiol 508: 949-953, 1998.
    • (1998) J Physiol , vol.508 , pp. 949-953
    • Ostrowski, K.1    Rohde, T.2    Zacho, M.3    Asp, S.4    Pedersen, B.K.5
  • 95
    • 0034537933 scopus 로고    scopus 로고
    • Physical activity and plasma interleukin-6 in humans-effect of intensity of exercise
    • Ostrowski K, Schjerling P, and Pedersen BK. Physical activity and plasma interleukin-6 in humans-effect of intensity of exercise. Eur J Appl Physiol 83: 512-515, 2000.
    • (2000) Eur J Appl Physiol , vol.83 , pp. 512-515
    • Ostrowski, K.1    Schjerling, P.2    Pedersen, B.K.3
  • 97
    • 0035016791 scopus 로고    scopus 로고
    • Human breast adipocytes express interleukin-6 (IL-6) and its receptor system: Increased IL-6 production by beta-adrenergic activation and effects of IL-6 on adipocyte function
    • Path G, Bornstein SR, Gurniak M, Chrousos GP, Scherbaum WA, and Hauner H. Human breast adipocytes express interleukin-6 (IL-6) and its receptor system: increased IL-6 production by beta-adrenergic activation and effects of IL-6 on adipocyte function. J Clin Endocrinol Metab 86: 2281-2288, 2001.
    • (2001) J Clin Endocrinol Metab , vol.86 , pp. 2281-2288
    • Path, G.1    Bornstein, S.R.2    Gurniak, M.3    Chrousos, G.P.4    Scherbaum, W.A.5    Hauner, H.6
  • 98
    • 0033922490 scopus 로고    scopus 로고
    • Exercise and the immune system: Regulation, integration and adaptation
    • Pedersen BK and Hoffman-Goetz L. Exercise and the immune system: regulation, integration and adaptation. Physiol Rev 80: 1055-1081, 2000.
    • (2000) Physiol Rev , vol.80 , pp. 1055-1081
    • Pedersen, B.K.1    Hoffman-Goetz, L.2
  • 100
    • 0035886973 scopus 로고    scopus 로고
    • Muscle-derived interleukin-6: Possible biological effects
    • Pedersen BK, Steensberg A, and Schjerling P. Muscle-derived interleukin-6: possible biological effects. J Physiol 536: 329-337, 2001.
    • (2001) J Physiol , vol.536 , pp. 329-337
    • Pedersen, B.K.1    Steensberg, A.2    Schjerling, P.3
  • 101
    • 0037397789 scopus 로고    scopus 로고
    • Circulating levels of TNF-alpha and IL-6-relation to truncal fat mass and muscle mass in healthy elderly individuals and in patients with type-2 diabetes
    • Pedersen M, Bruunsgaard H, Weis N, Hendel HW, Andreassen BU, Eldrup E, Dela F, and Pedersen BK. Circulating levels of TNF-alpha and IL-6-relation to truncal fat mass and muscle mass in healthy elderly individuals and in patients with type-2 diabetes. Mech Ageing Dev 124: 495-502, 2003.
    • (2003) Mech Ageing Dev , vol.124 , pp. 495-502
    • Pedersen, M.1    Bruunsgaard, H.2    Weis, N.3    Hendel, H.W.4    Andreassen, B.U.5    Eldrup, E.6    Dela, F.7    Pedersen, B.K.8
  • 103
    • 0642364997 scopus 로고    scopus 로고
    • Immunohistochemical detection of interleukin-6 in human skeletal muscle fibers following exercise
    • Penkowa M, Keller C, Keller P, Jauffred S, and Pedersen BK. Immunohistochemical detection of interleukin-6 in human skeletal muscle fibers following exercise. FASEB J 17: 2166-2168, 2003.
    • (2003) FASEB J , vol.17 , pp. 2166-2168
    • Penkowa, M.1    Keller, C.2    Keller, P.3    Jauffred, S.4    Pedersen, B.K.5
  • 104
    • 0029933665 scopus 로고    scopus 로고
    • Tumor necrosis factor (TNF)-alpha inhibits insulin signaling through stimulation of the p55 TNF receptor and activation of sphingomyelinase
    • Peraldi P, Hotamisligil GS, Buurman WA, White MF, and Spiegelman BM. Tumor necrosis factor (TNF)-alpha inhibits insulin signaling through stimulation of the p55 TNF receptor and activation of sphingomyelinase. J Biol Chem 271: 13018-13022, 1996.
    • (1996) J Biol Chem , vol.271 , pp. 13018-13022
    • Peraldi, P.1    Hotamisligil, G.S.2    Buurman, W.A.3    White, M.F.4    Spiegelman, B.M.5
  • 105
    • 11144325623 scopus 로고    scopus 로고
    • Acute IL-6 treatment increases fatty acid turnover in elderly humans in vivo and in tissue culture in vitro: Evidence that IL-6 acts independently of lipolytic hormones
    • Petersen EW, Carey AL, Sacchetti M, Steinberg GR, Macaulay SL, Febbraio MA, and Pedersen BK. Acute IL-6 treatment increases fatty acid turnover in elderly humans in vivo and in tissue culture in vitro: evidence that IL-6 acts independently of lipolytic hormones. Am J Physiol Endocrinol Metab 288: E155-E162, 2005.
    • (2005) Am J Physiol Endocrinol Metab , vol.288
    • Petersen, E.W.1    Carey, A.L.2    Sacchetti, M.3    Steinberg, G.R.4    Macaulay, S.L.5    Febbraio, M.A.6    Pedersen, B.K.7
  • 106
    • 1642377274 scopus 로고    scopus 로고
    • Impaired mitochondrial activity in the insulin-resistant offspring of patients with type 2 diabetes
    • Petersen KF, Dufour S, Befroy D, Garcia R, and Shulman GI. Impaired mitochondrial activity in the insulin-resistant offspring of patients with type 2 diabetes. N Engl J Med 350: 664-671, 2004.
    • (2004) N Engl J Med , vol.350 , pp. 664-671
    • Petersen, K.F.1    Dufour, S.2    Befroy, D.3    Garcia, R.4    Shulman, G.I.5
  • 107
    • 0030731621 scopus 로고    scopus 로고
    • NIDDM as a disease of the innate immune system: Association of acute-phase reactants and interleukin-6 with metabolic syndrome X
    • Pickup JC, Mattock MB, Chusney GD, and Burt D. NIDDM as a disease of the innate immune system: association of acute-phase reactants and interleukin-6 with metabolic syndrome X. Diabetologia 40: 1286-1292, 1997.
    • (1997) Diabetologia , vol.40 , pp. 1286-1292
    • Pickup, J.C.1    Mattock, M.B.2    Chusney, G.D.3    Burt, D.4
  • 108
    • 0742287196 scopus 로고    scopus 로고
    • Exercise training meta-analysis of trials in patients with chronic heart failure (ExTra-MATCH)
    • Piepoli MF, Davos C, Francis DP, and Coats AJ. Exercise training meta-analysis of trials in patients with chronic heart failure (ExTra-MATCH). BMJ 328: 189-195, 2004.
    • (2004) BMJ , vol.328 , pp. 189-195
    • Piepoli, M.F.1    Davos, C.2    Francis, D.P.3    Coats, A.J.4
  • 109
    • 29244483678 scopus 로고    scopus 로고
    • Influence of anti-TNF treatment on the cardiovascular risk factors in patients with active rheumatoid arthritis
    • Jul 1 [Epub ahead of print]
    • Popa C, Netea MG, Radstake T, van der Meer JW, Stalenhoef AF, Van Riel PL, and Barrera P. Influence of anti-TNF treatment on the cardiovascular risk factors in patients with active rheumatoid arthritis. Ann Rheum Dis Jul 1 [Epub ahead of print]: 2004.
    • (2004) Ann Rheum Dis
    • Popa, C.1    Netea, M.G.2    Radstake, T.3    Van Der Meer, J.W.4    Stalenhoef, A.F.5    Van Riel, P.L.6    Barrera, P.7
  • 110
    • 0035908632 scopus 로고    scopus 로고
    • C-reactive protein, interleukin 6, and risk of developing type 2 diabetes mellitus
    • Pradhan AD, Manson JE, Rifai N, Buring JE, and Ridker PM. C-reactive protein, interleukin 6, and risk of developing type 2 diabetes mellitus. JAMA 286: 327-334, 2001.
    • (2001) JAMA , vol.286 , pp. 327-334
    • Pradhan, A.D.1    Manson, J.E.2    Rifai, N.3    Buring, J.E.4    Ridker, P.M.5
  • 111
    • 0032817355 scopus 로고    scopus 로고
    • Interleukin-10: An anti-inflammatory cytokine with therapeutic potential
    • Pretolani M. Interleukin-10: an anti-inflammatory cytokine with therapeutic potential. Clin Exp Allergy 29: 1164-1171, 1999.
    • (1999) Clin Exp Allergy , vol.29 , pp. 1164-1171
    • Pretolani, M.1
  • 112
    • 0030023051 scopus 로고    scopus 로고
    • Acute phase levels of C-reactive protein enhance IL-1 beta and IL-1ra production by human blood monocytes but inhibit IL-1 beta and IL-1ra production by alveolar macrophages
    • Pue CA, Mortensen RF, Marsh CB, Pope HA, and Wewers MD. Acute phase levels of C-reactive protein enhance IL-1 beta and IL-1ra production by human blood monocytes but inhibit IL-1 beta and IL-1ra production by alveolar macrophages. J Immunol 156: 1594-1600, 1996.
    • (1996) J Immunol , vol.156 , pp. 1594-1600
    • Pue, C.A.1    Mortensen, R.F.2    Marsh, C.B.3    Pope, H.A.4    Wewers, M.D.5
  • 113
    • 0034161845 scopus 로고    scopus 로고
    • Down-regulation of cyclic-nucleotide phosphodiesterase 3B in 3T3-L1 adipocytes induced by tumour necrosis factor alpha and cAMP
    • Rahn-Landstrom T, Mei J, Karlsson M, Manganiello V, and Degerman E. Down-regulation of cyclic-nucleotide phosphodiesterase 3B in 3T3-L1 adipocytes induced by tumour necrosis factor alpha and cAMP. Biochem J 346: 337-343, 2000.
    • (2000) Biochem J , vol.346 , pp. 337-343
    • Rahn-Landstrom, T.1    Mei, J.2    Karlsson, M.3    Manganiello, V.4    Degerman, E.5
  • 114
    • 0034704893 scopus 로고    scopus 로고
    • Reactive protein and other markers of inflammation in the prediction of cardiovascular disease in women
    • Ridker PM, Hennekens CH, Buring JE, and Rifai NC. Reactive protein and other markers of inflammation in the prediction of cardiovascular disease in women. N Engl J Med 342: 836-843, 2000.
    • (2000) N Engl J Med , vol.342 , pp. 836-843
    • Ridker, P.M.1    Ch, H.2    Buring, J.E.3    Rifai, N.C.4
  • 115
    • 0034681920 scopus 로고    scopus 로고
    • Plasma concentration of interleukin-6 and the risk of future myocardial infarction among apparently healthy men
    • Ridker PM, Rifai N, Stampfer MJ, and Hennekens CH. Plasma concentration of interleukin-6 and the risk of future myocardial infarction among apparently healthy men. Circulation 101: 1767-1772, 2000.
    • (2000) Circulation , vol.101 , pp. 1767-1772
    • Ridker, P.M.1    Rifai, N.2    Stampfer, M.J.3    Hennekens, C.H.4
  • 116
    • 0037078969 scopus 로고    scopus 로고
    • Comparison of C-reactive protein and low-density lipoprotein cholesterol levels in the prediction of first cardiovascular events
    • Ridker PM, Rifai N, Rose L, Buring JE, and Cook NR. Comparison of C-reactive protein and low-density lipoprotein cholesterol levels in the prediction of first cardiovascular events. N Engl J Med 347: 1557-1565, 2002.
    • (2002) N Engl J Med , vol.347 , pp. 1557-1565
    • Ridker, P.M.1    Rifai, N.2    Rose, L.3    Buring, J.E.4    Cook, N.R.5
  • 118
    • 0033552883 scopus 로고    scopus 로고
    • Atherosclerosis-an inflammatory disease
    • Ross R. Atherosclerosis-an inflammatory disease. N Engl J Med 340: 115-126, 1999.
    • (1999) N Engl J Med , vol.340 , pp. 115-126
    • Ross, R.1
  • 119
    • 0017142296 scopus 로고
    • Hyperlipidemia and atherosclerosis
    • Ross R and Harker L. Hyperlipidemia and atherosclerosis. Science 193: 1094-1100, 1976.
    • (1976) Science , vol.193 , pp. 1094-1100
    • Ross, R.1    Harker, L.2
  • 120
    • 0242580711 scopus 로고    scopus 로고
    • Interleukin-6 (IL-6) induces insulin resistance in 3T3-L1 adipocytes and is, like IL-8 and tumor necrosis factor-alpha, overexpressed in human fat cells from insulin-resistant subjects
    • Rotter V, Nagaev I, and Smith U. Interleukin-6 (IL-6) induces insulin resistance in 3T3-L1 adipocytes and is, like IL-8 and tumor necrosis factor-alpha, overexpressed in human fat cells from insulin-resistant subjects. J Biol Chem 278: 45777-45784, 2003.
    • (2003) J Biol Chem , vol.278 , pp. 45777-45784
    • Rotter, V.1    Nagaev, I.2    Smith, U.3
  • 122
    • 0030028606 scopus 로고    scopus 로고
    • The expression of TNF alpha by human muscle. Relationship to insulin resistance
    • Saghizadeh M, Ong JM, Garvey WT, Henry RR, and Kern PA. The expression of TNF alpha by human muscle. Relationship to insulin resistance. J Clin Invest 97: 1111-1116, 1996.
    • (1996) J Clin Invest , vol.97 , pp. 1111-1116
    • Saghizadeh, M.1    Ong, J.M.2    Garvey, W.T.3    Henry, R.R.4    Kern, P.A.5
  • 123
    • 0025176658 scopus 로고
    • Correlations and interactions in the production of interleukin-6 (IL-6), IL-1, and tumor necrosis factor (TNF) in human blood mononuclear cells: IL-6 suppresses IL-1 and TNF
    • Schindler R, Mancilla J, Endres S, Ghorbani R, Clark SC, and Dinarello CA. Correlations and interactions in the production of interleukin-6 (IL-6), IL-1, and tumor necrosis factor (TNF) in human blood mononuclear cells: IL-6 suppresses IL-1 and TNF. Blood 75: 40-47, 1990.
    • (1990) Blood , vol.75 , pp. 40-47
    • Schindler, R.1    Mancilla, J.2    Endres, S.3    Ghorbani, R.4    Clark, S.C.5    Dinarello, C.A.6
  • 124
    • 0033549059 scopus 로고    scopus 로고
    • Long-term exercise and atherogenic activity of blood mononuclear cells in persons at risk of developing ischemic heart disease
    • Smith JK, Dykes R, Douglas JE, Krishnaswamy G, and Berk S. Long-term exercise and atherogenic activity of blood mononuclear cells in persons at risk of developing ischemic heart disease. JAMA 281: 1722-1727, 1999.
    • (1999) JAMA , vol.281 , pp. 1722-1727
    • Smith, J.K.1    Dykes, R.2    Douglas, J.E.3    Krishnaswamy, G.4    Berk, S.5
  • 125
    • 0032544690 scopus 로고    scopus 로고
    • Overexpression of perilipin a and B blocks the ability of tumor necrosis factor alpha to increase lipolysis in 3T3-L1 adipocytes
    • Souza SC, de Vargas LM, Yamamoto MT, Lien P, Franciosa MD, Moss LG, and Greenberg AS. Overexpression of perilipin A and B blocks the ability of tumor necrosis factor alpha to increase lipolysis in 3T3-L1 adipocytes. J Biol Chem 273: 24665-24669, 1998.
    • (1998) J Biol Chem , vol.273 , pp. 24665-24669
    • Souza, S.C.1    De Vargas, L.M.2    Yamamoto, M.T.3    Lien, P.4    Franciosa, M.D.5    Moss, L.G.6    Greenberg, A.S.7
  • 126
    • 0031948947 scopus 로고    scopus 로고
    • BRL 49653 blocks the lipolytic actions of tumor necrosis factor-alpha: A potential new insulin-sensitizing mechanism for thiazolidinediones
    • Souza SC, Yamamoto MT, Franciosa MD, Lien P, and Greenberg AS. BRL 49653 blocks the lipolytic actions of tumor necrosis factor-alpha: a potential new insulin-sensitizing mechanism for thiazolidinediones. Diabetes 47: 691-695, 1998.
    • (1998) Diabetes , vol.47 , pp. 691-695
    • Souza, S.C.1    Yamamoto, M.T.2    Franciosa, M.D.3    Lien, P.4    Greenberg, A.S.5
  • 127
    • 0038322493 scopus 로고    scopus 로고
    • Exercise and IL-6 infusion inhibit endotoxin-induced TNF-α production in humans
    • Starkie R, Ostrowski SR, Jauffred S, Febbraio M, and Pedersen BK. Exercise and IL-6 infusion inhibit endotoxin-induced TNF-α production in humans. FASEB J 17: 884-886, 2003.
    • (2003) FASEB J , vol.17 , pp. 884-886
    • Starkie, R.1    Ostrowski, S.R.2    Jauffred, S.3    Febbraio, M.4    Pedersen, B.K.5
  • 128
    • 0035369080 scopus 로고    scopus 로고
    • Carbohydrate ingestion attenuates the increase in plasma interleukin-6, but not skeletal muscle interleukin-6 mRNA, during exercise in humans
    • Starkie RL, Arkinstall MJ, Koukoulas I, Hawley JA, and Febbraio MA. Carbohydrate ingestion attenuates the increase in plasma interleukin-6, but not skeletal muscle interleukin-6 mRNA, during exercise in humans. J Physiol 533: 585-591, 2001.
    • (2001) J Physiol , vol.533 , pp. 585-591
    • Starkie, R.L.1    Arkinstall, M.J.2    Koukoulas, I.3    Hawley, J.A.4    Febbraio, M.A.5
  • 129
    • 0035006714 scopus 로고    scopus 로고
    • Circulating monocytes are not the source of elevations in plasma IL-6 and TNF-α levels after prolonged running
    • Starkie RL, Rolland J, Angus DJ, Anderson MJ, and Febbraio MA. Circulating monocytes are not the source of elevations in plasma IL-6 and TNF-α levels after prolonged running. Am J Physiol Cell Physiol 280: C769-C774, 2001.
    • (2001) Am J Physiol Cell Physiol , vol.280
    • Starkie, R.L.1    Rolland, J.2    Angus, D.J.3    Anderson, M.J.4    Febbraio, M.A.5
  • 130
    • 0035576798 scopus 로고    scopus 로고
    • Interleukin-6 production in contracting human skeletal muscle is influenced by pre-exercise muscle glycogen content
    • Steensberg A, Febbraio MA, Osada T, Schjerling P, van Hall G, Saltin B, and Pedersen BK. Interleukin-6 production in contracting human skeletal muscle is influenced by pre-exercise muscle glycogen content. J Physiol 537: 633-639, 2001.
    • (2001) J Physiol , vol.537 , pp. 633-639
    • Steensberg, A.1    Febbraio, M.A.2    Osada, T.3    Schjerling, P.4    Van Hall, G.5    Saltin, B.6    Pedersen, B.K.7
  • 135
    • 0034668926 scopus 로고    scopus 로고
    • Production of interleukin-6 in contracting human skeletal muscles can account for the exercise-induced increase in plasma interleukin-6
    • Steensberg A, van Hall G, Osada T, Sacchetti M, Saltin B, and Klarlund PB. Production of interleukin-6 in contracting human skeletal muscles can account for the exercise-induced increase in plasma interleukin-6. J Physiol 529: 237-242, 2000.
    • (2000) J Physiol , vol.529 , pp. 237-242
    • Steensberg, A.1    Van Hall, G.2    Osada, T.3    Sacchetti, M.4    Saltin, B.5    Klarlund, P.B.6
  • 140
    • 0034473259 scopus 로고    scopus 로고
    • Cross-sectional and prospective relationships of interleukin-6 and C-reactive protein with physical performance in elderly persons: MacArthur studies of successful aging
    • Taaffe DR, Harris TB, Ferrucci L, Rowe J, and Seeman TE. Cross-sectional and prospective relationships of interleukin-6 and C-reactive protein with physical performance in elderly persons: MacArthur studies of successful aging. J Gerontol A Biol Sci Med Sci 55: M709-M715, 2000.
    • (2000) J Gerontol a Biol Sci Med Sci , vol.55
    • Taaffe, D.R.1    Harris, T.B.2    Ferrucci, L.3    Rowe, J.4    Seeman, T.E.5
  • 141
    • 0040780540 scopus 로고    scopus 로고
    • Cooperative influence of genetic polymorphisms on interleukin 6 transcriptional regulation
    • Terry CF, Loukaci V, and Green FR. Cooperative influence of genetic polymorphisms on interleukin 6 transcriptional regulation. J Biol Chem 275: 18138-18144, 2000.
    • (2000) J Biol Chem , vol.275 , pp. 18138-18144
    • Terry, C.F.1    Loukaci, V.2    Green, F.R.3
  • 142
    • 0030823183 scopus 로고    scopus 로고
    • IL-6 and APPs: Anti-inflammatory and immunosuppressive mediators
    • Tilg H, Dinarello CA, and Mier JW. IL-6 and APPs: anti-inflammatory and immunosuppressive mediators. Immunol Today 18: 428-432, 1997.
    • (1997) Immunol Today , vol.18 , pp. 428-432
    • Tilg, H.1    Dinarello, C.A.2    Mier, J.W.3
  • 143
    • 0030777881 scopus 로고    scopus 로고
    • Exercise training for intermittent claudication: Does it adversely affect biochemical markers of the exercise-induced inflammatory response?
    • Tisi PV, Hulse M, Chulakadabba A, Gosling P, and Shearman CP. Exercise training for intermittent claudication: does it adversely affect biochemical markers of the exercise-induced inflammatory response? Eur J Vasc Endovasc Surg 14: 344-350, 1997.
    • (1997) Eur J Vasc Endovasc Surg , vol.14 , pp. 344-350
    • Tisi, P.V.1    Hulse, M.2    Chulakadabba, A.3    Gosling, P.4    Shearman, C.P.5
  • 145
    • 0032743517 scopus 로고    scopus 로고
    • Circulating tumour necrosis factor alpha concentrations are higher in abdominal versus peripheral obesity
    • Tsigos C, Kyrou I, Chala E, Tsapogas P, Stavridis JC, and Raptis SA. Circulating tumour necrosis factor alpha concentrations are higher in abdominal versus peripheral obesity. Metabolism 48: 1332-1335, 1999.
    • (1999) Metabolism , vol.48 , pp. 1332-1335
    • Tsigos, C.1    Kyrou, I.2    Chala, E.3    Tsapogas, P.4    Stavridis, J.C.5    Raptis, S.A.6
  • 146
    • 0028276385 scopus 로고
    • Bicycle exercise enhances plasma IL-6 but does not change IL-1α, IL-1β, IL-6, or TNF-α pre-mRNA in BMNC
    • Ullum H, Haahr PM, Diamant M, Palmo J, Halkjaer-Kristensen J, and Pedersen BK. Bicycle exercise enhances plasma IL-6 but does not change IL-1α, IL-1β, IL-6, or TNF-α pre-mRNA in BMNC. J Appl Physiol 77: 93-97, 1994.
    • (1994) J Appl Physiol , vol.77 , pp. 93-97
    • Ullum, H.1    Haahr, P.M.2    Diamant, M.3    Palmo, J.4    Halkjaer-Kristensen, J.5    Pedersen, B.K.6
  • 147
    • 0030756346 scopus 로고    scopus 로고
    • Protection from obesity-induced insulin resistance in mice lacking TNF-alpha function
    • Uysal KT, Wiesbrock SM, Marino MW, and Hotamisligil GS. Protection from obesity-induced insulin resistance in mice lacking TNF-alpha function. Nature 389: 610-614, 1997.
    • (1997) Nature , vol.389 , pp. 610-614
    • Uysal, K.T.1    Wiesbrock, S.M.2    Marino, M.W.3    Hotamisligil, G.S.4
  • 148
    • 0030056373 scopus 로고    scopus 로고
    • Epinephrine inhibits tumor necrosis factor-alpha and potentiates interleukin 10 production during human endotoxemia
    • Van der Poll T, Coyle SM, Barbosa K, Braxton CC, and Lowry SF. Epinephrine inhibits tumor necrosis factor-alpha and potentiates interleukin 10 production during human endotoxemia. J Clin Invest 97: 713-719, 1996.
    • (1996) J Clin Invest , vol.97 , pp. 713-719
    • Van Der Poll, T.1    Coyle, S.M.2    Barbosa, K.3    Braxton, C.C.4    Lowry, S.F.5
  • 150
    • 0034455007 scopus 로고    scopus 로고
    • Sleep apnea and daytime sleepiness and fatigue: Relation to visceral obesity, insulin resistance, and hypercytokinemia
    • Vgontzas AN, Papanicolaou DA, Bixler EO, Hopper K, Lotsikas A, and Lin HM. Sleep apnea and daytime sleepiness and fatigue: relation to visceral obesity, insulin resistance, and hypercytokinemia. J Clin Endocrinol Metab 85: 1151-1158, 2000.
    • (2000) J Clin Endocrinol Metab , vol.85 , pp. 1151-1158
    • Vgontzas, A.N.1    Papanicolaou, D.A.2    Bixler, E.O.3    Hopper, K.4    Lotsikas, A.5    Lin, H.M.6
  • 151
    • 0035916309 scopus 로고    scopus 로고
    • Cardiovascular disease, interleukin-6, and risk of mortality in older women: The women's health and aging study
    • Volpato S, Guralnik JM, Ferrucci L, Balfour J, Chaves P, Fried LP, and Harris TB. Cardiovascular disease, interleukin-6, and risk of mortality in older women: the women's health and aging study. Circulation 103: 947-953, 2001.
    • (2001) Circulation , vol.103 , pp. 947-953
    • Volpato, S.1    Guralnik, J.M.2    Ferrucci, L.3    Balfour, J.4    Chaves, P.5    Fried, L.P.6    Harris, T.B.7
  • 152
    • 0036066485 scopus 로고    scopus 로고
    • High white blood cell count is associated with a worsening of insulin sensitivity and predicts the development of type 2 diabetes
    • Vozarova B, Weyer C, Lindsay RS, Pratley RE, Bogardus C, and Tataranni PA. High white blood cell count is associated with a worsening of insulin sensitivity and predicts the development of type 2 diabetes. Diabetes 51: 455-461, 2002.
    • (2002) Diabetes , vol.51 , pp. 455-461
    • Vozarova, B.1    Weyer, C.2    Lindsay, R.S.3    Pratley, R.E.4    Bogardus, C.5    Tataranni, P.A.6
  • 154
    • 0028281708 scopus 로고
    • Interleukin-10 inhibits interleukin-8 production in human neutrophils
    • Wang P, Wu P, Anthes JC, Siegel MI, Egan RW, and Billah MM. Interleukin-10 inhibits interleukin-8 production in human neutrophils. Blood 83: 2678-2683, 1994.
    • (1994) Blood , vol.83 , pp. 2678-2683
    • Wang, P.1    Wu, P.2    Anthes, J.C.3    Siegel, M.I.4    Egan, R.W.5    Billah, M.M.6
  • 155
    • 0028365152 scopus 로고
    • IL-10 inhibits transcription of cytokine genes in human peripheral blood mononuclear cells
    • Wang P, Wu P, Siegel MI, Egan RW, and Billah MM. IL-10 inhibits transcription of cytokine genes in human peripheral blood mononuclear cells. J Immunol 153: 811-816, 1994.
    • (1994) J Immunol , vol.153 , pp. 811-816
    • Wang, P.1    Wu, P.2    Siegel, M.I.3    Egan, R.W.4    Billah, M.M.5
  • 157
    • 2642561229 scopus 로고    scopus 로고
    • Palmitate, but not unsaturated fatty acids, induces the expression of interleukin-6 in human myotubes through proteasome-dependent activation of nuclear factor kappa B
    • Weigert C, Brodbeck K, Staiger H, Kausch C, Machicao F, Haring HU, and Schleicher ED. Palmitate, but not unsaturated fatty acids, induces the expression of interleukin-6 in human myotubes through proteasome-dependent activation of nuclear factor kappa B. J Biol Chem 279: 23942-23952, 2004.
    • (2004) J Biol Chem , vol.279 , pp. 23942-23952
    • Weigert, C.1    Brodbeck, K.2    Staiger, H.3    Kausch, C.4    Machicao, F.5    Haring, H.U.6    Schleicher, E.D.7
  • 158
    • 0030954180 scopus 로고    scopus 로고
    • Effects of a polymorphism in the human tumor necrosis factor alpha promoter on transcriptional activation
    • Wilson AG, Symons JA, McDowell TL, McDevitt HO, and Duff GW. Effects of a polymorphism in the human tumor necrosis factor alpha promoter on transcriptional activation. Proc Natl Acad Sci USA 94: 3195-3199, 1997.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 3195-3199
    • Wilson, A.G.1    Symons, J.A.2    McDowell, T.L.3    McDevitt, H.O.4    Duff, G.W.5
  • 160
    • 2542421760 scopus 로고    scopus 로고
    • The global burden of chronic diseases: Overcoming impediments to prevention and control
    • Yach D, Hawkes C, Gould CL, and Hofman KJ. The global burden of chronic diseases: overcoming impediments to prevention and control. JAMA 291: 2616-2622, 2004.
    • (2004) JAMA , vol.291 , pp. 2616-2622
    • Yach, D.1    Hawkes, C.2    Gould, C.L.3    Hofman, K.J.4
  • 161
    • 0033761684 scopus 로고    scopus 로고
    • Acute impairment of insulin-mediated capillary recruitment and glucose uptake in rat skeletal muscle in vivo by TNF-alpha
    • Youd JM, Rattigan S, and Clark MG. Acute impairment of insulin-mediated capillary recruitment and glucose uptake in rat skeletal muscle in vivo by TNF-alpha. Diabetes 49: 1904-1909, 2000.
    • (2000) Diabetes , vol.49 , pp. 1904-1909
    • Youd, J.M.1    Rattigan, S.2    Clark, M.G.3
  • 162
    • 0036789186 scopus 로고    scopus 로고
    • Tumor necrosis factor-alpha stimulates lipolysis in differentiated human adipocytes through activation of extracellular signal-related kinase and elevation of intracellular cAMP
    • Zhang HH, Halbleib M, Ahmad F, Manganiello VC, and Greenberg AS. Tumor necrosis factor-alpha stimulates lipolysis in differentiated human adipocytes through activation of extracellular signal-related kinase and elevation of intracellular cAMP. Diabetes 51: 2929-2935, 2002.
    • (2002) Diabetes , vol.51 , pp. 2929-2935
    • Zhang, H.H.1    Halbleib, M.2    Ahmad, F.3    Manganiello, V.C.4    Greenberg, A.S.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.