Cystic fibrosis transmembrane conductance regulator modulators in cystic fibrosis: Current perspectives

Clinical Pharmacology: Advances and Applications

Volumn 8, Issue , 2016, Pages 127-140

  Schmidt, Béla Z ^a   Haaf, Jérémy B ^b   Leal, Teresinha ^b   Noel, Sabrina ^b  

^a UNIVERSITY OF LEUVEN   (Belgium)

^b UNIVERSITÉ CATHOLIQUE DE LOUVAIN   (Belgium)

Author keywords

Correctors; Drug repositioning; High throughput screening; Personalized medicine; Potentiators; Precision medicine

Indexed keywords

ABBV 974; ABC TRANSPORTER; ADENOSINE TRIPHOSPHATE; ATALUREN; CHLORIDE CHANNEL; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; GLPG 1837; IBUPROFEN; IVACAFTOR; IVACAFTOR PLUS LUMACAFTOR; LUMACAFTOR; N 91115; PHOSPHODIESTERASE V INHIBITOR; QBW 251; RESPIRATORY TRACT AGENT; RIOCIGUAT; SILDENAFIL; TEZACAFTOR; UNCLASSIFIED DRUG; VARDENAFIL;

BINDING AFFINITY; CELL MEMBRANE; CFTR GENE; CHLORIDE TRANSPORT; CYSTIC FIBROSIS; DRUG EFFICACY; DRUG ELIMINATION; DRUG MECHANISM; DRUG REPOSITIONING; DRUG RESPONSE; DRUG SAFETY; DRUG TOLERABILITY; ERECTILE DYSFUNCTION; EXON; FORCED EXPIRATORY VOLUME; GENE; GENE EXPRESSION; GENE MUTATION; GENE STRUCTURE; GENOTYPE; HUMAN; NONHUMAN; NONSENSE MUTATION; PERSONALIZED MEDICINE; PHASE 2 CLINICAL TRIAL (TOPIC); PHENOTYPE; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN DEPHOSPHORYLATION; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN PROCESSING; PULMONARY HYPERTENSION; REVIEW; STRUCTURE ACTIVITY RELATION; TREATMENT DURATION;

EID: 84992109815     PISSN: None     EISSN: 11791438     Source Type: Journal    
DOI: 10.2147/CPAA.S100759     Document Type: Review

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