Autophagy stimulation by rapamycin suppresses lung inflammation and infection by Burkholderia cenocepacia in a model of cystic fibrosis

Autophagy

Volumn 7, Issue 11, 2011, Pages 1359-1370

  Abdulrahman, Basant A ^a   Khweek, Arwa Abu ^a   Akhter, Anwari ^a   Caution, Kyle ^a   Kotrange, Sheetal ^a   Abdelaziz, Dalia H A ^a   Newland, Christie ^a   Rosales Reyes, Roberto ^d   Kopp, Benjamin ^c   McCoy, Karen ^c   Montione, Richard ^b   Schlesinger, Larry S ^a   Gavrilin, Mikhail A ^a   Wewers, Mark D ^a   Valvano, Miguel A ^d   Amer, Amal O ^a  

^a Center for Microbial Interface Biology   (United States)

^b OHIO STATE UNIVERSITY   (United States)

^c NATIONWIDE CHILDREN S HOSPITAL   (United States)

^d UNIVERSITY OF WESTERN ONTARIO   (Canada)

Author keywords

Autophagy; Burkholderia cenocepacia; Cystic fibrosis; Host pathogen interaction; Inflammation; Macrophages; Rapamycin

Indexed keywords

AUTOPHAGY PROTEIN 12; AUTOPHAGY PROTEIN 5; AUTOPHAGY PROTEIN 8; AUTOPHAGY PROTEIN 9B; CELL PROTEIN; INTERLEUKIN 1BETA; INTERLEUKIN 6; LC3 PROTEIN; RAPAMYCIN; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBACTERIAL ACTIVITY; ANTIINFLAMMATORY ACTIVITY; ARTICLE; AUTOPHAGOSOME; AUTOPHAGY; BACTERIAL GROWTH; BACTERIAL LOAD; BACTERIAL SURVIVAL; BURKHOLDERIA CENOCEPACIA; BURKHOLDERIA CENOCEPACIA INFECTION; BURKHOLDERIA INFECTION; CELL VACUOLE; CONTROLLED STUDY; CYSTIC FIBROSIS; CYTOKINE PRODUCTION; DOWN REGULATION; GENE EXPRESSION REGULATION; GENE SILENCING; LYSOSOME; MACROPHAGE; MOUSE; NONHUMAN; RNA INTERFERENCE; WILD TYPE;

BACTERIA (MICROORGANISMS); BURKHOLDERIA CENOCEPACIA; MUS;

EID: 80655134731     PISSN: 15548627     EISSN: 15548635     Source Type: Journal    
DOI: 10.4161/auto.7.11.17660     Document Type: Article

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